Detailed information for compound 1091486

Basic information

Technical information
  • TDR Targets ID: 1091486
  • Name: 2-cyclohexyl-3-oxo-1H-isoindole-4-carboxamide
  • MW: 258.316 | Formula: C15H18N2O2
  • H donors: 1 H acceptors: 2 LogP: 1.64 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N(Cc2c1c(ccc2)C(=O)N)C1CCCCC1
  • InChi: 1S/C15H18N2O2/c16-14(18)12-8-4-5-10-9-17(15(19)13(10)12)11-6-2-1-3-7-11/h4-5,8,11H,1-3,6-7,9H2,(H2,16,18)
  • InChiKey: AEDVPHAKDUNUHG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-cyclohexyl-3-oxo-isoindoline-4-carboxamide
  • 2-cyclohexyl-3-oxo-4-isoindolinecarboxamide
  • 2-cyclohexyl-3-keto-isoindoline-4-carboxamide
  • MLS000116948
  • SMR000093902
  • ChemDiv2_006582
  • IDI1_005297

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens huntingtin Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens poly (ADP-ribose) polymerase 1 Starlite/ChEMBL References
Homo sapiens estrogen receptor 2 (ER beta) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni poly [ADP-ribose] polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Echinococcus multilocularis poly (ADP ribose) polymerase 1 Get druggable targets OG5_128423 All targets in OG5_128423
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus WGR domain containing protein Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma congolense poly(ADP-ribose) polymerase, putative Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma mansoni poly [ADP-ribose] polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma brucei poly(adp-ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma japonicum Poly [ADP-ribose] polymerase 2, putative Get druggable targets OG5_128423 All targets in OG5_128423
Entamoeba histolytica poly(ADP-ribose) polymerase, putative Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma japonicum Poly [ADP-ribose] polymerase 1, putative Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Neospora caninum hypothetical protein Get druggable targets OG5_128423 All targets in OG5_128423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128423 All targets in OG5_128423
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum Poly [ADP-ribose] polymerase 1, putative Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Brugia malayi WGR domain containing protein Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma japonicum Poly [ADP-ribose] polymerase 2-A, putative Get druggable targets OG5_128423 All targets in OG5_128423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus granulosus poly (ADP ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni poly [ADP-ribose] polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum ko:K00774 NAD ADP-ribosyltransferase [EC2.4.2.30], putative Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus granulosus poly (ADP ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis poly (adp ribose) polymerase 2 Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus granulosus poly ADP ribose polymerase 1 Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus multilocularis poly (ADP ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Loa Loa (eye worm) poly(ADP-ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Brugia malayi WGR domain containing protein Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative Get druggable targets OG5_128423 All targets in OG5_128423
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus poly (ADP ribose) polymerase Get druggable targets OG5_128423 All targets in OG5_128423
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus poly adp ribose polymerase 2 Get druggable targets OG5_128423 All targets in OG5_128423
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Entamoeba histolytica hypothetical protein Get druggable targets OG5_128423 All targets in OG5_128423
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative Get druggable targets OG5_128423 All targets in OG5_128423
Onchocerca volvulus Huntingtin homolog Get druggable targets OG5_132837 All targets in OG5_132837
Schistosoma japonicum Poly [ADP-ribose] polymerase 2, putative Get druggable targets OG5_128423 All targets in OG5_128423
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi hypothetical protein Get druggable targets OG5_132837 All targets in OG5_132837
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei gambiense poly(ADP-ribose) polymerase, putative Get druggable targets OG5_128423 All targets in OG5_128423
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Loa Loa (eye worm) hypothetical protein estrogen receptor 2 (ER beta) 495 aa 418 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0016 0.0229
Trypanosoma cruzi casein kinase, putative 0.0157 0.0087 0.1981
Brugia malayi Inositol-1 0.03 0.0188 0.1108
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0127 0.0065 0.1526
Echinococcus multilocularis thioredoxin glutathione reductase 0.0365 0.0234 0.0234
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0099 0.0045 0.0175
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0169 0.0096 0.2338
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0071 0.0026 0.0098
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.7036 0.4965 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.0026 0.0188
Brugia malayi MH1 domain containing protein 0.0064 0.0021 0.0118
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0059 0.0017 0.0471
Schistosoma mansoni GTP-binding protein alpha subunit 0.0036 0.0001 0.0002
Schistosoma mansoni polycystin 1-related 0.0039 0.0003 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Brugia malayi TAR-binding protein 0.0125 0.0064 0.0376
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.0072 0.0027 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0016 0.0316
Onchocerca volvulus 0.0063 0.002 0.0143
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0106 0.0051 0.0089
Brugia malayi orphan nuclear receptor NR2E1 0.0063 0.002 0.0116
Schistosoma mansoni rab6-interacting 0.0039 0.0003 0.001
Mycobacterium ulcerans dehydrogenase 0.0044 0.0006 0.0009
Echinococcus granulosus casein kinase i 0.0157 0.0087 0.0338
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Echinococcus granulosus cathepsin l1 0.0051 0.0011 0.0042
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0157 0.0087 0.051
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.0073 0.1072
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0123 0.0062 0.0062
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0071 0.0026 0.0149
Mycobacterium leprae conserved hypothetical protein 0.04 0.0259 0.4054
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.03 0.0188 0.4521
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.009 0.0039 0.0151
Brugia malayi MH2 domain containing protein 0.0115 0.0057 0.0334
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0173 0.0098 0.2696
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0536 0.0356 0.2625
Entamoeba histolytica hypothetical protein 0.0367 0.0236 0.3318
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0092 0.004 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Brugia malayi hypothetical protein 0.0152 0.0083 0.0488
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0036 0.0001 0.0002
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0063 0.002 0.002
Echinococcus granulosus replication factor c subunit 1 0.0058 0.0016 0.0061
Onchocerca volvulus 0.0204 0.012 0.0885
Leishmania major prostaglandin f synthase, putative 0.0062 0.002 0.0477
Schistosoma mansoni RAR-like nuclear receptor 0.0134 0.0071 0.0273
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0098 0.0045 0.1192
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Onchocerca volvulus 0.0039 0.0003 0.0019
Onchocerca volvulus 0.0051 0.0011 0.008
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0057 0.0334
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0134 0.0071 0.0273
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0063 0.0114
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0327 0.0207 0.0206
Schistosoma mansoni aspartyl aminopeptidase (M18 family) 0.0072 0.0027 0.0102
Loa Loa (eye worm) hypothetical protein 0.0152 0.0083 0.0488
Echinococcus granulosus Niemann Pick C1 protein 0.1477 0.1023 0.3998
Loa Loa (eye worm) hypothetical protein 0.0444 0.029 0.1709
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0065 0.0253
Mycobacterium leprae Probable pyruvate kinase PykA 0.0352 0.0225 0.35
Loa Loa (eye worm) hypothetical protein 0.0706 0.0476 0.2807
Trypanosoma cruzi DNA polymerase eta, putative 0.0092 0.004 0.0838
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0151 0.0083 0.1876
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0083 0.0034 0.0131
Onchocerca volvulus 0.0051 0.0011 0.008
Echinococcus granulosus jumonji domain containing protein 0.0163 0.0091 0.0353
Mycobacterium ulcerans DNA polymerase IV 0.012 0.006 0.0118
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0062 0.002 0.0477
Trypanosoma cruzi PAB1-binding protein , putative 0.0177 0.0101 0.233
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Trichomonas vaginalis glutaminase, putative 0.054 0.0359 0.2646
Loa Loa (eye worm) hypothetical protein 0.0092 0.004 0.0235
Plasmodium falciparum acyl-CoA synthetase 0.0314 0.0198 0.5522
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Trypanosoma brucei phosphoglycerate kinase 0.0197 0.0115 0.2739
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0123 0.0063 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0016 0.0113
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0093 0.0041 0.024
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Echinococcus multilocularis GPCR, family 2 0.0327 0.0207 0.0206
Echinococcus granulosus phosphoglycerate kinase 1 0.0536 0.0356 0.1389
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0036 0.0001 0.0002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0134 0.0071 0.0273
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0001 0.0002
Echinococcus granulosus sterol regulatory element binding protein 0.0444 0.029 0.1132
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0008 0.0029
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0058 0.0016 0.0113
Plasmodium falciparum lipid/sterol:H+ symporter 0.0063 0.002 0.0475
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0107 0.0052 0.1109
Trichomonas vaginalis penicillin-binding protein, putative 0.04 0.0259 0.1912
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0494 0.0326 0.1921
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0174 0.0099 0.0383
Brugia malayi hypothetical protein 0.0148 0.008 0.0471
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0012 0.0067
Echinococcus granulosus dna polymerase kappa 0.012 0.006 0.0234
Brugia malayi Hexokinase family protein 0.0048 0.001 0.0054
Echinococcus granulosus Immunoglobulin 0.0049 0.001 0.0037
Echinococcus granulosus JmjC domain containing protein 4 0.0053 0.0013 0.0048
Schistosoma mansoni smad 0.0115 0.0057 0.0221
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0134 0.0071 0.0413
Echinococcus multilocularis lysine specific demethylase 6a 0.0053 0.0013 0.0012
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0003 0.001
Schistosoma mansoni nuclear receptor 0.0063 0.002 0.0077
Schistosoma mansoni jumonji/arid domain-containing protein 0.0214 0.0127 0.0495
Loa Loa (eye worm) CXXC zinc finger family protein 0.0207 0.0122 0.0718
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0026 0.0359
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0577 0.0385 0.1503
Loa Loa (eye worm) MBCTL1 0.0052 0.0013 0.0071
Onchocerca volvulus 0.04 0.0259 0.1914
Echinococcus granulosus dnaJ subfamily B 0.1665 0.1156 0.452
Loa Loa (eye worm) hypothetical protein 0.0071 0.0026 0.0148
Echinococcus granulosus ecdysone induced protein 78C 0.0134 0.0071 0.0273
Schistosoma mansoni hypothetical protein 0.0327 0.0207 0.0808
Echinococcus multilocularis pyruvate kinase 0.018 0.0103 0.0103
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.004 0.0235
Brugia malayi hypothetical protein 0.0367 0.0236 0.1388
Echinococcus granulosus translational activator gcn1 0.0039 0.0003 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0134 0.0071 0.0413
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.002 0.0113
Echinococcus multilocularis importin subunit beta 1 0.0207 0.0122 0.0121
Brugia malayi mothers against decapentaplegic homolog 3 0.0051 0.0012 0.0067
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Onchocerca volvulus 0.0063 0.002 0.0143
Echinococcus multilocularis hexokinase 0.0077 0.003 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0134 0.0071 0.007
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Onchocerca volvulus 0.0123 0.0063 0.046
Loa Loa (eye worm) oxidoreductase 0.0062 0.002 0.0113
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0036 0.0001 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.042 0.0273 0.0547
Echinococcus granulosus dual specificity protein kinase clk2 0.0127 0.0065 0.0253
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0134 0.0071 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0134 0.0071 0.0413
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Loa Loa (eye worm) RNA binding protein 0.0125 0.0064 0.0376
Trypanosoma brucei glucosidase, putative 0.0072 0.0026 0.0581
Toxoplasma gondii cathepsin CPL 0.0051 0.0011 0.0305
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Schistosoma mansoni cpg binding protein 0.0222 0.0133 0.0518
Schistosoma mansoni steroid hormone receptor ad4bp 0.0134 0.0071 0.0273
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0053 0.0013 0.0013
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0197 0.0115 0.3231
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0292 0.0183 0.4385
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.0026 0.064
Echinococcus granulosus muscleblind protein 0.0148 0.0081 0.0313
Plasmodium vivax SET domain protein, putative 0.0249 0.0152 0.4215
Loa Loa (eye worm) importin-beta domain-containing protein 0.0039 0.0003 0.0015
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Plasmodium falciparum M18 aspartyl aminopeptidase 0.0072 0.0027 0.0664
Giardia lamblia Replication factor C, subunit 1 0.0058 0.0016 0.0016
Echinococcus granulosus pyruvate kinase 0.0352 0.0225 0.0877
Schistosoma mansoni vesicular amine transporter 0.0057 0.0016 0.0059
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0063 0.002 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0016 0.0109
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0576 0.0384 0.0761
Schistosoma mansoni hypothetical protein 0.0185 0.0107 0.0416
Loa Loa (eye worm) hypothetical protein 0.0094 0.0042 0.0244
Brugia malayi steroid hormone receptor 0.0134 0.0071 0.0413
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0123 0.0063 0.0904
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.009 0.0039 0.0152
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.044
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0003 0.0003
Echinococcus granulosus aldo keto reductase 0.0062 0.002 0.0075
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0107 0.0052 0.0051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0536 0.0356 0.8585
Brugia malayi Thioredoxin reductase 0.0364 0.0234 0.1377
Entamoeba histolytica protein kinase domain containing protein 0.0184 0.0106 0.1487
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0011 0.0147
Loa Loa (eye worm) DnaJ domain-containing protein 0.0185 0.0107 0.0627
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.03 0.0188 0.5067
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0033 0.0194
Chlamydia trachomatis DNA ligase 0.0057 0.0016 0.0282
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0031 0.0119
Loa Loa (eye worm) beta-lactamase 0.04 0.0259 0.1528
Echinococcus multilocularis casein kinase I alpha 0.0157 0.0087 0.0086
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0001 0.0002
Echinococcus multilocularis mothers against decapentaplegic 6 0.0051 0.0012 0.0011
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0123 0.0063 0.0114
Trypanosoma brucei phosphoglycerate kinase, putative 0.0197 0.0115 0.2739
Trichomonas vaginalis CMGC family protein kinase 0.0127 0.0065 0.0475
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.005 0.0691
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0057 0.0016 0.0113
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0123 0.0063 0.0114
Mycobacterium tuberculosis Conserved protein 0.04 0.0259 0.051
Schistosoma mansoni hypothetical protein 0.004 0.0004 0.0014
Brugia malayi polk-prov protein 0.0056 0.0016 0.0088
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0134 0.0071 0.0273
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0098 0.0045 0.0327
Schistosoma mansoni niemann-pick C1 (NPC1) 0.105 0.072 0.2812
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Brugia malayi N-terminal motif family protein 0.0721 0.0487 0.2872
Schistosoma mansoni aldo-keto reductase 0.0062 0.002 0.0075
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Loa Loa (eye worm) oxidoreductase 0.0062 0.002 0.0113
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0003 0.0003
Echinococcus multilocularis mothers against decapentaplegic 5 0.0115 0.0057 0.0057
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0063 0.002 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Mycobacterium ulcerans pyruvate kinase 0.0352 0.0225 0.0449
Loa Loa (eye worm) pyruvate kinase 0.0352 0.0225 0.1324
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0053 0.0013 0.0074
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0839 0.057 0.3365
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.005 0.0362
Brugia malayi hypothetical protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.008 0.0032 0.0032
Loa Loa (eye worm) hepatopoietin HPO2 0.0107 0.0052 0.03
Entamoeba histolytica acyl-CoA synthetase, putative 0.042 0.0273 0.3845
Brugia malayi intracellular kinase 0.0197 0.0115 0.0677
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0134 0.0071 0.0413
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0003 0.0003
Plasmodium vivax pyruvate kinase, putative 0.0352 0.0225 0.6287
Echinococcus multilocularis translational activator gcn1 0.0039 0.0003 0.0003
Echinococcus granulosus tachykinin peptides receptor 99D 0.0342 0.0218 0.0849
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0197 0.0115 0.0677
Trichomonas vaginalis antibiotic synthetase, putative 0.0123 0.0063 0.0458
Schistosoma mansoni Smad4 0.0051 0.0012 0.0044
Loa Loa (eye worm) cysteine protease 0.0051 0.0011 0.0064
Schistosoma mansoni alpha glucosidase 0.0072 0.0026 0.0101
Brugia malayi hypothetical protein 0.0039 0.0003 0.0016
Toxoplasma gondii isocitrate dehydrogenase 0.0083 0.0034 0.0944
Brugia malayi Muscleblind-like protein 0.0148 0.0081 0.0472
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0296 0.0186 0.0362
Brugia malayi Pre-SET motif family protein 0.0249 0.0152 0.0892
Loa Loa (eye worm) hypothetical protein 0.0078 0.0031 0.0179
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0127 0.0065 0.1446
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0123 0.0062 0.0242
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.042 0.0273 0.4273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0062 0.0122
Loa Loa (eye worm) hexokinase 0.0048 0.001 0.0054
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0036 0.0001 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0006 0.0091
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0924 0.063 0.1258
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.04 0.0259 0.0519
Brugia malayi Calcitonin receptor-like protein seb-1 0.1032 0.0708 0.4175
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0117 0.0058 0.0226
Trichomonas vaginalis bromodomain-containing protein, putative 0.0173 0.0098 0.0719
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0026 0.0188
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0169 0.0096 0.2313
Giardia lamblia Kinase, CMGC GSK 0.0197 0.0115 0.293
Onchocerca volvulus 0.0082 0.0033 0.0243
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0123 0.0063 0.0367
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0115 0.0057 0.0221
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0026 0.0188
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0044 0.0006 0.0091
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0126 0.0065 0.1753
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Onchocerca volvulus Protein ultraspiracle homolog 0.0134 0.0071 0.0517
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0001 0.0002
Toxoplasma gondii PHD-finger domain-containing protein 0.0117 0.0058 0.1627
Brugia malayi MH2 domain containing protein 0.0051 0.0012 0.0067
Onchocerca volvulus Pyruvate kinase homolog 0.0352 0.0225 0.1658
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0075 0.0029 0.0166
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0095 0.0043 0.0902
Plasmodium vivax hypothetical protein, conserved 0.04 0.0259 0.7268
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Schistosoma mansoni phosphoglycerate kinase 0.0536 0.0356 0.1389
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0134 0.0071 0.0413
Onchocerca volvulus 0.0062 0.002 0.0141
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.002 0.002
Trypanosoma brucei aspartyl aminopeptidase, putative 0.0072 0.0027 0.0586
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0016 0.0229
Echinococcus granulosus dnaJ subfamily C 6 0.0185 0.0107 0.0416
Loa Loa (eye worm) hypothetical protein 0.0327 0.0207 0.1219
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0008 0.0029
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0157 0.0087 0.1981
Schistosoma mansoni jumonji/arid domain-containing protein 0.0214 0.0127 0.0495
Loa Loa (eye worm) hypoxia-induced factor 1 0.0155 0.0085 0.05
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.009 0.0039 0.0956
Echinococcus multilocularis musashi 0.0168 0.0095 0.0094
Loa Loa (eye worm) aspartyl aminopeptidase 0.0072 0.0027 0.0153
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0123 0.0063 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.01 0.0046 0.0179
Leishmania major GTP-binding protein, putative 0.0131 0.0068 0.1657
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0126 0.0065 0.0127
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0099 0.0045 0.0079
Brugia malayi Myosin head containing protein 0.0063 0.002 0.0114
Schistosoma mansoni hypothetical protein 0.01 0.0046 0.0179
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Mycobacterium ulcerans glutaminase 0.054 0.0359 0.0719
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.008 0.0032 0.0124
Entamoeba histolytica hypothetical protein 0.0367 0.0236 0.3318
Loa Loa (eye worm) hypothetical protein 0.0165 0.0093 0.0543
Onchocerca volvulus Alhambra homolog 0.0117 0.0058 0.0427
Schistosoma mansoni serine/threonine protein kinase 0.0184 0.0106 0.0413
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.001 0.0055
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0057 0.0016 0.0333
Brugia malayi amine oxidase, flavin-containing family protein 0.0044 0.0006 0.0034
Leishmania major acetyl-CoA synthetase, putative 0.0123 0.0063 0.1521
Schistosoma mansoni smad1 5 8 and 0.0115 0.0057 0.0221
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0087 0.0037 0.0839
Brugia malayi Fibronectin type III domain containing protein 0.0049 0.001 0.0055
Leishmania major cathepsin L-like protease 0.0051 0.0011 0.0276
Schistosoma mansoni importin beta-1 0.0207 0.0122 0.0475
Trichomonas vaginalis importin beta-1, putative 0.0168 0.0094 0.069
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0126 0.0065 0.152
Trypanosoma brucei unspecified product 0.0063 0.002 0.0432
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.005 0.0691
Loa Loa (eye worm) pyruvate kinase 0.0352 0.0225 0.1324
Trypanosoma brucei DNA polymerase kappa, putative 0.0056 0.0016 0.0316
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.005 0.1154
Brugia malayi hypothetical protein 0.0049 0.001 0.0055
Loa Loa (eye worm) latrophilin receptor protein 2 0.0327 0.0207 0.1219
Trypanosoma cruzi cruzipain precursor, putative 0.0193 0.0112 0.2605
Plasmodium vivax acetyl-CoA synthetase, putative 0.0123 0.0063 0.1692
Loa Loa (eye worm) hypothetical protein 0.0314 0.0198 0.1164
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0098 0.0045 0.0327
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Loa Loa (eye worm) MH2 domain-containing protein 0.1691 0.1174 0.6931
Echinococcus multilocularis pyruvate kinase 0.0352 0.0225 0.0224
Toxoplasma gondii HEAT repeat-containing protein 0.0207 0.0122 0.342
Trichomonas vaginalis CK1 family protein kinase 0.0157 0.0087 0.0636
Brugia malayi Niemann-Pick C1 protein precursor 0.1034 0.0708 0.418
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0038 0.0003 0.0056
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0026 0.0188
Leishmania major macrophage migration inhibitory factor-like protein 0.0167 0.0094 0.2266
Loa Loa (eye worm) bromodomain containing protein 0.0049 0.001 0.0055
Entamoeba histolytica protein kinase, putative 0.0197 0.0115 0.1616
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.006 0.1326
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.009 0.0039 0.069
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Onchocerca volvulus 0.0051 0.0011 0.008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0134 0.0071 0.007
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0123 0.0063 0.0904
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0095 0.0043 0.0166
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0134 0.0071 0.0273
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0008 0.0056
Mycobacterium ulcerans oxidoreductase 0.0044 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Plasmodium vivax casein kinase 1, putative 0.0157 0.0087 0.2377
Brugia malayi nuclear receptor RXR 0.0071 0.0026 0.0148
Mycobacterium ulcerans 6-phosphofructokinase 0.0105 0.005 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0123 0.0063 0.0904
Plasmodium vivax phosphoglycerate kinase, putative 0.0536 0.0356 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0126 0.0065 0.152
Trypanosoma cruzi trypanothione reductase, putative 0.0126 0.0065 0.144
Toxoplasma gondii patched family protein 0.0063 0.002 0.0545
Toxoplasma gondii propionate-CoA ligase 0.0123 0.0063 0.1753
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0033 0.0128
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0184 0.0106 0.257
Entamoeba histolytica hypothetical protein 0.0367 0.0236 0.3318
Loa Loa (eye worm) hypothetical protein 0.0064 0.0021 0.0118
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.01 0.0047 0.018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.04 0.0259 0.051
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0068 0.0024 0.0091
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0011 0.0077
Loa Loa (eye worm) isocitrate dehydrogenase 0.0083 0.0034 0.0198
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0003 0.0016
Loa Loa (eye worm) pyruvate kinase 0.0074 0.0028 0.0162
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.005 0.0362
Loa Loa (eye worm) hypothetical protein 0.0071 0.0026 0.0148
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0016 0.0015
Onchocerca volvulus 0.04 0.0259 0.1914
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0036 0.0001 0.0002
Trypanosoma cruzi hexokinase, putative 0.0077 0.003 0.0581
Onchocerca volvulus 0.1942 0.1352 1
Trichomonas vaginalis DNA polymerase eta, putative 0.012 0.006 0.0439
Mycobacterium ulcerans acyl-CoA synthetase 0.042 0.0273 0.0547
Brugia malayi DKFZp564C0469 protein 0.0057 0.0016 0.0092
Onchocerca volvulus 0.0494 0.0326 0.2407
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0134 0.0071 0.007
Brugia malayi Pax transcription activation domain interacting protein 0.0057 0.0016 0.0092
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.042 0.0273 0.0538
Echinococcus granulosus importin subunit beta 1 0.0207 0.0122 0.0475
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.009 0.0039 0.0899
Onchocerca volvulus 0.0063 0.002 0.0143
Onchocerca volvulus 0.0157 0.0087 0.0639
Schistosoma mansoni phosphoglycerate kinase 0.0536 0.0356 0.1389
Plasmodium falciparum histone acetyltransferase GCN5 0.0154 0.0085 0.232
Leishmania major aspartyl aminopeptidase, putative,metallo-peptidase, Clan MH, Family M20 0.0072 0.0027 0.0644
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0327 0.0207 0.1219
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0051 0.0012 0.0134
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0127 0.0065 0.1446
Onchocerca volvulus 0.0197 0.0115 0.0848
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0197 0.0115 0.2677
Mycobacterium ulcerans monoamine oxidase 0.0044 0.0006 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0051 0.0011 0.0233
Echinococcus granulosus hypothetical protein 0.0062 0.002 0.0075
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0131 0.0068 0.1526
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0056 0.0015 0.0057
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.0176 0.4698
Trypanosoma cruzi hypothetical protein, conserved 0.04 0.0259 0.6218
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0036 0.0001 0.0002
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0131 0.0068 0.0401
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0057 0.0016 0.0029
Echinococcus granulosus hexokinase 0.0077 0.003 0.0115
Toxoplasma gondii NADPH-glutathione reductase 0.0126 0.0065 0.1814
Schistosoma mansoni hypothetical protein 0.2206 0.154 0.6019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0001 0.0002
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0044 0.0006 0.0023
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0026 0.0188
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0045 0.1044
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0126 0.0065 0.1753
Echinococcus multilocularis expressed conserved protein 0.0971 0.0664 0.0663
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0044 0.0006 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0134 0.0071 0.0413
Trichomonas vaginalis CK1 family protein kinase 0.0157 0.0087 0.0636
Onchocerca volvulus Protein patched homolog 0.0063 0.002 0.0143
Plasmodium vivax ataxin-2 like protein, putative 0.0177 0.0101 0.278
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Echinococcus granulosus death domain containing protein 0.01 0.0046 0.0179
Echinococcus multilocularis jumonji domain containing 1A 0.0053 0.0013 0.0012
Brugia malayi WGR domain containing protein 0.0095 0.0043 0.0251
Plasmodium falciparum replication factor C subunit 1, putative 0.0058 0.0016 0.0371
Toxoplasma gondii patched family protein 0.0063 0.002 0.0545
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1032 0.0708 0.4175
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0314 0.0198 0.548
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.006 0.0018 0.0018
Loa Loa (eye worm) hexokinase 0.0077 0.003 0.0174
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0839 0.057 0.2228
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.04 0.0259 0.1012
Leishmania major protein kinase, putative 0.0127 0.0065 0.1578
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Schistosoma mansoni patched 1 0.0444 0.029 0.1132
Loa Loa (eye worm) hypothetical protein 0.0051 0.0012 0.0067
Loa Loa (eye worm) hexokinase type II 0.0077 0.003 0.0174
Echinococcus granulosus Protein patched homolog 1 0.0444 0.029 0.1132
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0536 0.0356 0.2625
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0197 0.0115 0.2791
Brugia malayi CXXC zinc finger family protein 0.0207 0.0122 0.0718
Plasmodium vivax glycogen synthase kinase 3, putative 0.0197 0.0115 0.3181
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0126 0.0065 0.152
Echinococcus granulosus pyruvate kinase 0.018 0.0103 0.0402
Mycobacterium leprae Probable lipase LipE 0.04 0.0259 0.4054
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0131 0.0068 0.0401
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0134 0.0071 0.0273
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0536 0.0356 1
Plasmodium vivax patched family protein, putative 0.0063 0.002 0.0475
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.0026 0.0188
Trypanosoma brucei PAB1-binding protein , putative 0.0177 0.0101 0.2401
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0123 0.0063 0.1521
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Schistosoma mansoni importin-beta 2 0.0039 0.0003 0.001
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.005 0.0193
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0342 0.0218 0.0217
Schistosoma mansoni smad 0.0051 0.0012 0.0044
Echinococcus multilocularis cysteine protease 0.0051 0.0011 0.0011
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0036 0.0001 0.0002
Trichomonas vaginalis ap endonuclease, putative 0.0169 0.0096 0.07
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0026 0.0148
Echinococcus multilocularis Immunoglobulin 0.0049 0.001 0.0009
Entamoeba histolytica hypothetical protein 0.0184 0.0106 0.1487
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0034 0.0768
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.009 0.0039 0.0076
Trichomonas vaginalis CK1 family protein kinase 0.0157 0.0087 0.0636
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0197 0.0115 0.267
Brugia malayi Protein kinase domain containing protein 0.0106 0.0051 0.0295
Echinococcus granulosus GTP binding nuclear protein Ran 0.0131 0.0068 0.0265
Trypanosoma cruzi casein kinase, putative 0.0157 0.0087 0.1981
Echinococcus granulosus histone acetyltransferase KAT2B 0.0557 0.037 0.1446
Onchocerca volvulus 0.0051 0.0011 0.008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0117 0.0058 0.1565
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0131 0.0068 0.1526
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.1573
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0029 0.0028
Plasmodium falciparum pyruvate kinase 0.0352 0.0225 0.6287
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0011 0.004
Onchocerca volvulus 0.0152 0.0083 0.0611
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0044 0.0006 0.0091
Trichomonas vaginalis myo inositol monophosphatase, putative 0.03 0.0188 0.1386
Onchocerca volvulus 0.0063 0.002 0.0143
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0036 0.0001 0.0002
Schistosoma mansoni DNA polymerase eta 0.0092 0.004 0.0156
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0134 0.0071 0.0273
Schistosoma mansoni zinc finger protein 0.0064 0.0021 0.0079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0839 0.057 0.057
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0617 0.0413 1
Schistosoma mansoni intermediate filament proteins 0.0168 0.0095 0.0368
Leishmania major aldo-keto reductase-like protein 0.0062 0.002 0.0477
Trypanosoma cruzi trypanothione reductase, putative 0.0364 0.0234 0.5589
Trypanosoma cruzi aldo/keto reductase, putative 0.0062 0.002 0.0327
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0134 0.0071 0.0273
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0134 0.0071 0.0517
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0092 0.004 0.0156
Echinococcus granulosus hexokinase 0.0077 0.003 0.0115
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0063 0.0114
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0012 0.0236
Schistosoma mansoni 6-phosphofructokinase 0.0105 0.005 0.0193
Brugia malayi casein kinase I 0.0157 0.0087 0.051
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0059
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0123 0.0062 0.0113
Schistosoma mansoni ets-related 0.0227 0.0137 0.0532
Echinococcus granulosus zinc finger protein 0.0064 0.0021 0.0079
Entamoeba histolytica acyl-CoA synthetase, putative 0.042 0.0273 0.3845
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0143 0.0077 0.0297
Mycobacterium tuberculosis Probable oxidoreductase 0.0062 0.002 0.0027
Entamoeba histolytica aldose reductase, putative 0.0062 0.002 0.0264
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0011 0.008
Entamoeba histolytica protein kinase, putative 0.0184 0.0106 0.1487
Loa Loa (eye worm) TAR-binding protein 0.0125 0.0064 0.0376
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.0073 0.0144
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.009 0.0039 0.0813
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0536 0.0356 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0134 0.0071 0.0413
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0126 0.0065 0.1753
Mycobacterium tuberculosis Probable hydrolase 0.04 0.0259 0.051
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0012 0.0011
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.005 0.0291
Entamoeba histolytica casein kinase, putative 0.0157 0.0087 0.1215
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Leishmania major importin beta-1 subunit, putative 0.0168 0.0094 0.2282
Trichomonas vaginalis penicillin-binding protein, putative 0.04 0.0259 0.1912
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0083 0.0034 0.0877
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.002 0.0113
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0011 0.0011
Echinococcus granulosus fetal alzheimer antigen falz 0.0056 0.0015 0.0057
Brugia malayi PHD-finger family protein 0.0117 0.0058 0.0341
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0134 0.0071 0.0413
Echinococcus multilocularis Niemann Pick C1 protein 0.1034 0.0708 0.0708
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.009 0.0039 0.0229
Toxoplasma gondii aldose reductase, putative 0.0062 0.002 0.0539
Onchocerca volvulus 0.0062 0.002 0.0141
Schistosoma mansoni protein kinase 0.0157 0.0087 0.0338
Brugia malayi hypothetical protein 0.0071 0.0026 0.0148
Loa Loa (eye worm) hypothetical protein 0.0216 0.0128 0.0754
Schistosoma mansoni hypothetical protein 0.0509 0.0336 0.1313
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0364 0.0234 0.0459
Echinococcus granulosus single minded 2 0.0037 0.0002 0.0004
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.011 0.0053 0.0053
Leishmania major hypothetical protein, conserved 0.0107 0.0052 0.1247
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0098 0.0045 0.1257
Schistosoma mansoni hypothetical protein 0.0428 0.0279 0.1087
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0013 0.0047
Trichomonas vaginalis CMGC family protein kinase 0.0197 0.0115 0.0846
Onchocerca volvulus 0.04 0.0259 0.1914
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0012 0.0044
Leishmania major phosphoglycerate kinase C, glycosomal 0.0536 0.0356 0.8607
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.03 0.0188 0.0376
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.044 0.0287 0.1121
Echinococcus granulosus protein kinase shaggy 0.0197 0.0115 0.0449
Brugia malayi hypothetical protein 0.0063 0.002 0.0116
Leishmania major hypothetical protein, conserved 0.0039 0.0003 0.0077
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Brugia malayi Uncoordinated protein 44 0.01 0.0046 0.027
Brugia malayi AMP-binding enzyme family protein 0.042 0.0273 0.1609
Mycobacterium ulcerans esterase/lipase LipP 0.04 0.0259 0.0519
Brugia malayi ecdysteroid receptor 0.0134 0.0071 0.0413
Brugia malayi beta-lactamase 0.04 0.0259 0.1528
Loa Loa (eye worm) intermediate filament protein 0.0168 0.0095 0.0556
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.002 0.0077
Trypanosoma cruzi casein kinase, putative 0.0157 0.0087 0.1981
Toxoplasma gondii macrophage migration inhibitory factor, putative 0.0167 0.0094 0.262
Plasmodium vivax M18 aspartyl aminopeptidase, putative 0.0072 0.0027 0.0664
Brugia malayi Probable ClpP-like protease 0.0079 0.0031 0.018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0003 0.001
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0314 0.0198 0.0395
Echinococcus multilocularis isocitrate dehydrogenase 0.0083 0.0034 0.0033
Brugia malayi hypothetical protein 0.0039 0.0003 0.0016
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0169 0.0096 0.235
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0073 0.0027 0.0027
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Loa Loa (eye worm) hypothetical protein 0.0506 0.0334 0.1971
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.009 0.0039 0.0039
Trypanosoma brucei DNA polymerase eta, putative 0.0092 0.004 0.0923
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0174 0.0099 0.1378
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0839 0.057 0.2228
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Trypanosoma cruzi metallo-peptidase, Clan MH, Family M20 0.0072 0.0027 0.0497
Loa Loa (eye worm) hypothetical protein 0.0148 0.0081 0.0472
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0033 0.0128
Onchocerca volvulus Cathepsin F homolog 0.0051 0.0011 0.008
Toxoplasma gondii patched family protein 0.0063 0.002 0.0545
Schistosoma mansoni Smad4 0.0051 0.0012 0.0044
Trichomonas vaginalis replication factor C large subunit, putative 0.0058 0.0016 0.0113
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0064 0.0249
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0112 0.2605
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0169 0.0096 0.2192
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0016 0.0109
Trypanosoma cruzi hypothetical protein, conserved 0.04 0.0259 0.6218
Trypanosoma cruzi aspartyl aminopeptidase, putative 0.0072 0.0027 0.0497
Echinococcus granulosus hexokinase type 2 0.0077 0.003 0.0115
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0071 0.0026 0.0148
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0002 0.0006
Brugia malayi Phosphoglycerate kinase 0.0197 0.0115 0.0676
Giardia lamblia Macrophage migration inhibitory factor 0.0167 0.0094 0.2292
Loa Loa (eye worm) hypothetical protein 0.0039 0.0003 0.0016
Schistosoma mansoni hypothetical protein 0.0367 0.0236 0.092
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0123 0.0063 0.1468
Onchocerca volvulus Huntingtin homolog 0.0148 0.008 0.059
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0016 0.0113
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0125 0.0064 0.0376
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.007 0.0025 0.0097
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0059
Brugia malayi Ets-domain containing protein 0.0075 0.0029 0.0165
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0001 0.0002
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0235 0.0142 0.0554
Echinococcus multilocularis cpg binding protein 0.0222 0.0133 0.0133
Echinococcus multilocularis snurportin 1 0.2206 0.154 0.1539
Schistosoma mansoni pyruvate kinase 0.0352 0.0225 0.0877
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Brugia malayi jmjC domain containing protein 0.0053 0.0013 0.0073
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Echinococcus granulosus mixed lineage leukemia protein mll 0.006 0.0018 0.0069
Schistosoma mansoni microtubule-associated protein tau 0.3641 0.2557 1
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0026 0.0148
Echinococcus granulosus snurportin 1 0.2206 0.154 0.6019
Echinococcus granulosus histone lysine methyltransferase setb 0.0282 0.0175 0.0684
Entamoeba histolytica aldose reductase, putative 0.0062 0.002 0.0264
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0036 0.0001 0.0002
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2558 0.1789 0.3596
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0839 0.057 0.2228
Echinococcus multilocularis transportin 1 0.0039 0.0003 0.0003
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0013 0.0047
Schistosoma mansoni hypothetical protein 0.0428 0.0279 0.1087
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0072 0.0027 0.0189
Entamoeba histolytica macrophage migration inhibitory factor-like protein 0.0167 0.0094 0.1309
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0169 0.0096 0.0371
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0184 0.0106 0.2524
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Trichomonas vaginalis pyruvate kinase, putative 0.0352 0.0225 0.1656
Leishmania major cathepsin L-like protease 0.0051 0.0011 0.0276
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0079 0.0031 0.0182
Chlamydia trachomatis pyruvate kinase 0.0352 0.0225 0.6253
Leishmania major phosphoglycerate kinase B, cytosolic 0.0536 0.0356 0.8607
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0056 0.0015 0.0014
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0016 0.038
Brugia malayi beta-lactamase family protein 0.04 0.0259 0.1528
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.008 0.0032 0.0124
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0444 0.029 0.1709
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0053 0.0013 0.0048
Brugia malayi MH1 domain containing protein 0.0115 0.0057 0.0334
Toxoplasma gondii aldehyde dehydrogenase 0.0123 0.0062 0.1742
Onchocerca volvulus 0.0036 0.0001 0.0003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0134 0.0071 0.0413
Echinococcus multilocularis PHD finger protein rhinoceros 0.0117 0.0058 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0839 0.057 0.2228
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0131 0.0068 0.1912
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0098 0.0045 0.1248
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0016 0.0089
Onchocerca volvulus 0.0151 0.0083 0.0607
Echinococcus multilocularis mixed lineage leukemia protein mll 0.006 0.0018 0.0018
Echinococcus granulosus Smad4 0.0115 0.0057 0.0221
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0051 0.0012 0.0084
Toxoplasma gondii exonuclease III APE 0.0169 0.0096 0.2676
Toxoplasma gondii HEAT repeat-containing protein 0.0039 0.0003 0.0073
Echinococcus granulosus PHD finger protein rhinoceros 0.0117 0.0058 0.0226
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0036 0.0001 0.0002
Entamoeba histolytica protein kinase, putative 0.0184 0.0106 0.1487
Mycobacterium tuberculosis Conserved protein 0.04 0.0259 0.051
Echinococcus granulosus aldo keto reductase 0.0062 0.002 0.0075
Echinococcus multilocularis dual specificity 0.0184 0.0106 0.0106
Leishmania major pyruvate kinase 0.0352 0.0225 0.544
Trypanosoma brucei aspartyl aminopeptidase, putative 0.0072 0.0027 0.0586
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.0026 0.0101
Leishmania major UDP-galactopyranose mutase 0.0044 0.0006 0.0155
Echinococcus granulosus geminin 0.1221 0.0842 0.3289
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0123 0.0063 0.0114
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0126 0.0065 0.1573
Mycobacterium leprae Conserved hypothetical protein 0.0044 0.0007 0.0008
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.01 0.0046 0.0046
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Echinococcus multilocularis thyroid hormone receptor alpha 0.0264 0.0162 0.0162
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0036 0.0001 0.0002
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.0026 0.0188
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0036 0.0001 0.0002
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0036 0.0001 0.0002
Toxoplasma gondii HEAT repeat-containing protein 0.0039 0.0003 0.0073
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0012 0.0011
Leishmania major cathepsin L-like protease 0.0051 0.0011 0.0276
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Brugia malayi WGR domain containing protein 0.0174 0.0099 0.0578
Schistosoma mansoni terminal deoxycytidyl transferase 0.0092 0.004 0.0156
Plasmodium falciparum ataxin-2 like protein, putative 0.0177 0.0101 0.278
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0105 0.005 0.0698
Plasmodium vivax macrophage migration inhibitory factor, putative 0.0167 0.0094 0.2566
Leishmania major pantothenate kinase subunit, putative 0.0051 0.0012 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Loa Loa (eye worm) pyruvate kinase 0.0352 0.0225 0.1324
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Brugia malayi CHE-14 protein 0.0444 0.029 0.1709
Loa Loa (eye worm) hypothetical protein 0.0071 0.0026 0.0148
Brugia malayi hypothetical protein 0.0036 0.0001 0.0002
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0619 0.0415 0.0832
Echinococcus granulosus RUN 0.0039 0.0003 0.001
Brugia malayi Bromodomain containing protein 0.0136 0.0072 0.0419
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0536 0.0356 1
Echinococcus multilocularis aldo keto reductase 0.0062 0.002 0.0019
Onchocerca volvulus 0.042 0.0273 0.2015
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0063 0.002 0.002
Brugia malayi Immunoglobulin I-set domain containing protein 0.0053 0.0013 0.0074
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Trypanosoma brucei hexokinase 0.0077 0.003 0.0669
Brugia malayi pyruvate kinase, muscle isozyme 0.0074 0.0028 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Echinococcus granulosus tumor protein p63 0.3458 0.2427 0.9491
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0126 0.0065 0.144
Brugia malayi hypothetical protein 0.0177 0.0101 0.0594
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0026 0.0098
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Echinococcus multilocularis FTZ F1 alpha 0.0134 0.0071 0.007
Echinococcus multilocularis aldo keto reductase 0.0062 0.002 0.0019
Treponema pallidum hexokinase (hxk) 0.0077 0.003 0.0406
Onchocerca volvulus 0.0506 0.0334 0.2469
Echinococcus multilocularis dna polymerase kappa 0.012 0.006 0.006
Loa Loa (eye worm) 6-phosphofructokinase 0.0105 0.005 0.0291
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0176 0.01 0.2313
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0134 0.0071 0.0413
Entamoeba histolytica acetyltransferase, GNAT family 0.0154 0.0085 0.1187
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0169 0.0096 0.2265
Echinococcus multilocularis pyruvate kinase 0.018 0.0103 0.0103
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0123 0.0062 0.1511
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.03 0.0188 0.447
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.0026 0.0152
Onchocerca volvulus 0.0063 0.002 0.0145
Echinococcus granulosus neuroglian 0.0049 0.001 0.0037
Trypanosoma cruzi pyruvate kinase 2, putative 0.0352 0.0225 0.5368
Echinococcus granulosus netrin receptor unc 5 0.01 0.0046 0.0179
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Brugia malayi Latrophilin receptor protein 2 0.0327 0.0207 0.1219
Schistosoma mansoni GTP-binding protein alpha subunit 0.0036 0.0001 0.0002
Loa Loa (eye worm) glutathione reductase 0.0364 0.0234 0.1377
Brugia malayi hypothetical protein 0.0114 0.0057 0.0331
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0184 0.0106 0.2453
Plasmodium falciparum importin beta, putative 0.0207 0.0122 0.3371
Loa Loa (eye worm) hypothetical protein 0.01 0.0047 0.0272
Mycobacterium ulcerans oxidoreductase 0.0062 0.002 0.0036
Loa Loa (eye worm) kap beta 3 protein 0.0039 0.0003 0.0015
Onchocerca volvulus 0.0168 0.0095 0.0697
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1032 0.0708 0.4175
Schistosoma mansoni hypothetical protein 0.0428 0.0279 0.1087
Leishmania major hypothetical protein, conserved 0.0177 0.0101 0.2449
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0036 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0112 0.2605
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.002 0.0138
Trypanosoma cruzi cysteine peptidase, putative 0.0193 0.0112 0.2605
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Leishmania major casein kinase, putative 0.0157 0.0087 0.2105
Entamoeba histolytica hypothetical protein 0.0367 0.0236 0.3318
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0039 0.0003 0.0015
Echinococcus multilocularis protein kinase shaggy 0.0197 0.0115 0.0115
Plasmodium vivax glutathione reductase, putative 0.0364 0.0234 0.6542
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0062 0.002 0.0477
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.04 0.0259 0.051
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0197 0.0115 0.267
Echinococcus multilocularis lamin 0.0168 0.0095 0.0094
Echinococcus multilocularis ecdysone induced protein 78C 0.0134 0.0071 0.007
Loa Loa (eye worm) patched family protein 0.0063 0.002 0.0114
Trichomonas vaginalis pyruvate kinase, putative 0.0352 0.0225 0.1656
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0009 0.0057
Echinococcus granulosus poly adp ribose polymerase 2 0.0095 0.0043 0.0166
Brugia malayi hypothetical protein 0.0168 0.0094 0.0554
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0016 0.0059
Entamoeba histolytica pyruvate kinase, putative 0.0245 0.0149 0.2097
Loa Loa (eye worm) hypothetical protein 0.0053 0.0013 0.0073
Echinococcus multilocularis mothers against decapentaplegic 2 0.0051 0.0012 0.0011
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.7036 0.4965 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0003 0.0016
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.002 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Treponema pallidum NADH oxidase 0.0126 0.0065 0.1436
Loa Loa (eye worm) phosphofructokinase 0.0105 0.005 0.0291
Echinococcus granulosus intermediate filament protein 0.0168 0.0095 0.0368
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0063 0.002 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0214 0.0127 0.0747
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Brugia malayi PHD-finger family protein 0.0075 0.0028 0.0164
Echinococcus granulosus WGR domain containing protein 0.0054 0.0014 0.0051
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0123 0.0063 0.1387
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0127 0.0065 0.182
Loa Loa (eye worm) hypothetical protein 0.0052 0.0013 0.0071
Toxoplasma gondii Erv1 / Alr family protein 0.0107 0.0052 0.1434
Loa Loa (eye worm) hypothetical protein 0.0054 0.0014 0.0076
Onchocerca volvulus 0.0062 0.002 0.0141
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0107 0.0052 0.1371
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0169 0.0096 0.0095
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0008 0.0008
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0105 0.005 0.0993
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0049 0.001 0.0037
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Echinococcus multilocularis casein kinase i 0.0157 0.0087 0.0086
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0924 0.063 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0031 0.0862
Trypanosoma cruzi importin beta-1 subunit, putative 0.0168 0.0094 0.216
Onchocerca volvulus 0.0123 0.0063 0.046
Echinococcus granulosus thyroid hormone receptor alpha 0.0063 0.002 0.0077
Brugia malayi MH1 domain containing protein 0.0115 0.0057 0.0334
Brugia malayi Nuclear hormone receptor E75 0.0063 0.002 0.0116
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.0073 0.0135
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0619 0.0415 0.0832
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0011 0.0064
Giardia lamblia Pyruvate kinase 0.0352 0.0225 0.6151
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Brugia malayi jmjC domain containing protein 0.0053 0.0013 0.0073
Brugia malayi Pyruvate kinase, M2 isozyme 0.0352 0.0225 0.1324
Loa Loa (eye worm) jmjC domain-containing protein 0.0241 0.0147 0.0862
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0003 0.001
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Brugia malayi F/Y-rich N-terminus family protein 0.0114 0.0056 0.0329
Brugia malayi mbt repeat family protein 0.0046 0.0008 0.0044
Brugia malayi Intermediate filament tail domain containing protein 0.0168 0.0095 0.0556
Brugia malayi cytoplasmic intermediate filament protein 0.009 0.0039 0.0229
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0079 0.0031 0.0182
Loa Loa (eye worm) hypothetical protein 0.0109 0.0053 0.0309
Trichomonas vaginalis set domain proteins, putative 0.1941 0.1352 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0051 0.0012 0.0236
Schistosoma mansoni loxhd1 0.0039 0.0003 0.001
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.006 0.1326
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.012 0.006 0.0439
Brugia malayi Protein kinase domain containing protein 0.0127 0.0065 0.0381
Schistosoma mansoni rab6-interacting 0.0039 0.0003 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Leishmania major macrophage migration inhibitory factor-like protein 0.0167 0.0094 0.2266
Schistosoma mansoni jumonji domain containing protein 0.0053 0.0013 0.0048
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0003 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.2423 0.1694 0.1693
Plasmodium falciparum thioredoxin reductase 0.0364 0.0234 0.6542
Plasmodium falciparum phosphoglycerate kinase 0.0536 0.0356 1
Trichomonas vaginalis conserved hypothetical protein 0.0444 0.029 0.2139
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0011 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0169 0.0096 0.2192
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus granulosus phd:f box containing protein 0.0053 0.0013 0.0048
Brugia malayi RNA recognition motif domain containing protein 0.0125 0.0064 0.0376
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0106 0.0051 0.0297
Plasmodium falciparum glutathione reductase 0.0364 0.0234 0.6542
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0134 0.0071 0.007
Giardia lamblia Pyruvate kinase 0.018 0.0103 0.2581
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.042 0.0273 0.4273
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0013 0.0012
Echinococcus granulosus aldo keto reductase 0.0062 0.002 0.0075
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0072 0.0027 0.0189
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0134 0.0071 0.0273
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.042 0.0273 0.0538
Schistosoma mansoni aldo-keto reductase 0.0062 0.002 0.0075
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.0176 0.4706
Loa Loa (eye worm) hypothetical protein 0.0071 0.0026 0.0148
Brugia malayi phosphofructokinase 0.0105 0.005 0.0291
Schistosoma mansoni hypothetical protein 0.0314 0.0198 0.0773
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Trichomonas vaginalis inositol monophosphatase, putative 0.03 0.0188 0.1386
Brugia malayi tailless protein 0.0063 0.002 0.0116
Loa Loa (eye worm) hypothetical protein 0.0079 0.0031 0.018
Plasmodium vivax replication factor C subunit 1, putative 0.0058 0.0016 0.0371
Echinococcus multilocularis casein kinase I alpha 0.0157 0.0087 0.0086
Echinococcus multilocularis Niemann Pick C1 protein 0.1477 0.1023 0.1022
Echinococcus multilocularis pyruvate kinase 0.0278 0.0172 0.0172
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0062 0.0122
Trichomonas vaginalis myo inositol monophosphatase, putative 0.03 0.0188 0.1386
Trypanosoma brucei prostaglandin f synthase 0.0062 0.002 0.0417
Echinococcus multilocularis cdgsh iron sulfur domain containing protein 0.048 0.0316 0.0315
Brugia malayi acetyltransferase, GNAT family protein 0.0577 0.0385 0.2269
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0831 0.0565 0.1126
Loa Loa (eye worm) patched family protein 0.0063 0.002 0.0114
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Brugia malayi MH2 domain containing protein 0.1691 0.1174 0.6931
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0126 0.0065 0.1436
Brugia malayi AMP-binding enzyme family protein 0.042 0.0273 0.1609
Brugia malayi ImpB/MucB/SamB family protein 0.0092 0.004 0.0235
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0721 0.0487 0.3598
Onchocerca volvulus 0.0077 0.003 0.0217
Echinococcus granulosus cpg binding protein 0.0222 0.0133 0.0518
Chlamydia trachomatis phosphoglycerate kinase 0.0536 0.0356 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.008 0.0032 0.0032
Mycobacterium ulcerans acetyl-CoA synthetase 0.0123 0.0063 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0327 0.0207 0.0808
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0057 0.0016 0.0113
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.2206 0.154 0.9089
Treponema pallidum phosphoglycerate kinase 0.0536 0.0356 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0157 0.0087 0.051
Brugia malayi 6-phosphofructokinase 0.0105 0.005 0.0291
Loa Loa (eye worm) hypothetical protein 0.0132 0.0069 0.0405
Loa Loa (eye worm) hypothetical protein 0.0036 0.0001 0.0002
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Loa Loa (eye worm) macrophage migration inhibitory factor 0.0167 0.0094 0.0549
Toxoplasma gondii hypothetical protein 0.0063 0.002 0.0545
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0249 0.0152 0.0591
Brugia malayi Fli-1 protein 0.0227 0.0137 0.0803
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0016 0.0015
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.0026 0.0152
Loa Loa (eye worm) hypothetical protein 0.0051 0.0011 0.0064
Loa Loa (eye worm) hypothetical protein 0.0062 0.002 0.0113
Plasmodium falciparum pyruvate kinase 2 0.018 0.0103 0.2844
Brugia malayi RNA binding protein 0.0125 0.0064 0.0376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Plasmodium falciparum hexokinase 0.0077 0.003 0.0762
Schistosoma mansoni bromodomain containing protein 0.015 0.0082 0.0317
Schistosoma mansoni nuclear hormone receptor 0.0134 0.0071 0.0273
Echinococcus granulosus lysine specific histone demethylase 1A 0.0044 0.0006 0.0023
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0352 0.0225 0.044
Brugia malayi Phosphoglycerate kinase 0.0536 0.0356 0.2097
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.002 0.0138
Plasmodium vivax acyl-CoA synthetase, putative 0.0314 0.0198 0.5522
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0036 0.0001 0.0002
Loa Loa (eye worm) glutaminase 0.054 0.0359 0.2113
Echinococcus granulosus casein kinase I alpha 0.0157 0.0087 0.0338
Trypanosoma cruzi pyruvate kinase 2, putative 0.0352 0.0225 0.5368
Loa Loa (eye worm) hypothetical protein 0.0148 0.008 0.0471
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0169 0.0096 0.0561
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0081 0.0033 0.0127
Loa Loa (eye worm) hypothetical protein 0.0204 0.012 0.0706
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0051 0.0011 0.0064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0134 0.0071 0.0413
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.042 0.0273 0.0547
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0062 0.0242
Brugia malayi Patched related family protein 12 0.0063 0.002 0.0114
Trichomonas vaginalis mercuric reductase, putative 0.0126 0.0065 0.0473
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Giardia lamblia Histone acetyltransferase GCN5 0.0154 0.0085 0.2037
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0016 0.0113
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.002 0.0138
Schistosoma mansoni ran 0.0131 0.0068 0.0265
Giardia lamblia Aldose reductase 0.0062 0.002 0.0118
Schistosoma mansoni nephrin 0.0049 0.001 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0367 0.0236 0.092
Loa Loa (eye worm) hypothetical protein 0.0178 0.0102 0.0598
Schistosoma mansoni alpha-glucosidase 0.0279 0.0173 0.0675
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.009 0.0039 0.0685
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Schistosoma mansoni nuclear hormone receptor 0.0063 0.002 0.0077
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0168 0.0094 0.069
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0044 0.0006 0.0091
Leishmania major cathepsin L-like protease 0.0051 0.0011 0.0276
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0093 0.0041 0.024
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0081 0.0033 0.0032
Leishmania major cysteine peptidase A (CPA) 0.0051 0.0011 0.0276
Schistosoma mansoni hypothetical protein 0.0706 0.0476 0.1859
Echinococcus multilocularis casein kinase I alpha 0.0157 0.0087 0.0086
Brugia malayi hypothetical protein 0.0063 0.002 0.0116
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0839 0.057 0.2228
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0098 0.0045 0.0327
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0049 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0117 0.0058 0.0341
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Toxoplasma gondii ATPase, AAA family protein 0.0058 0.0016 0.0441
Trichomonas vaginalis ap endonuclease, putative 0.0169 0.0096 0.07
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0131 0.0068 0.1852
Schistosoma mansoni ankyrin 23/unc44 0.01 0.0046 0.0179
Brugia malayi Patched related family protein 10 0.0063 0.002 0.0114
Loa Loa (eye worm) fli-1 protein 0.0227 0.0137 0.0803
Onchocerca volvulus 0.0039 0.0003 0.0019
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.008 0.0032 0.0031
Leishmania major acetyl-CoA synthetase, putative 0.0123 0.0063 0.1521
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0036 0.0001 0.0002
Leishmania major hexokinase, putative 0.0077 0.003 0.0727
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0057 0.0016 0.0242
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0282 0.0175 0.0175
Echinococcus granulosus 6 phosphofructokinase 0.0105 0.005 0.0193
Leishmania major cathepsin L-like protease 0.0193 0.0112 0.2719
Plasmodium falciparum thioredoxin reductase 0.0126 0.0065 0.1753
Trypanosoma cruzi aldo-keto reductase 0.0062 0.002 0.0327
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0134 0.0071 0.0413
Brugia malayi hypothetical protein 0.0057 0.0016 0.0092
Schistosoma mansoni cellular tumor antigen P53 0.0506 0.0334 0.1305
Onchocerca volvulus Pyruvate kinase homolog 0.0352 0.0225 0.1658
Schistosoma mansoni retinoic acid receptor RXR 0.0134 0.0071 0.0273
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0105 0.005 0.0088
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0249 0.0152 0.0151
Schistosoma mansoni smad1 5 8 and 0.0115 0.0057 0.0221
Onchocerca volvulus 0.0051 0.0011 0.008
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.002 0.0113
Leishmania major DNA polymerase kappa, putative 0.0099 0.0045 0.1099
Echinococcus multilocularis aldehyde reductase 0.0044 0.0007 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.009 0.0039 0.0152
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.013 0.0067 0.0261
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0063 0.0114
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0617 0.0413 1
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0068 0.0024 0.0138
Giardia lamblia Kinase, CK1 Casein kinase 0.0157 0.0087 0.2096
Trypanosoma brucei trypanothione reductase 0.0364 0.0234 0.563
Toxoplasma gondii histone lysine-specific demethylase 0.0044 0.0006 0.0164
Echinococcus granulosus cathepsin l cysteine peptidase 0.0051 0.0011 0.0042
Schistosoma mansoni transcription factor LCR-F1 0.0367 0.0236 0.092
Schistosoma mansoni inositol monophosphatase 0.03 0.0188 0.0734
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0016 0.0109
Loa Loa (eye worm) hypothetical protein 0.0036 0.0001 0.0002
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0134 0.0071 0.0273
Echinococcus granulosus cathepsin L cysteine proteinase 0.0051 0.0011 0.0042
Brugia malayi topoisomerase 0.0057 0.0016 0.0092
Brugia malayi Isocitrate dehydrogenase 0.0083 0.0034 0.0198
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0064 0.0249
Echinococcus granulosus GPCR family 2 0.0327 0.0207 0.0808
Onchocerca volvulus 0.0123 0.0063 0.046
Schistosoma mansoni zinc finger protein 0.0063 0.002 0.0077
Echinococcus granulosus importin 5 0.0039 0.0003 0.001
Entamoeba histolytica hypothetical protein 0.0057 0.0016 0.0215
Loa Loa (eye worm) hypothetical protein 0.0138 0.0074 0.0431
Toxoplasma gondii pyruvate kinase PyKII 0.018 0.0103 0.2897
Loa Loa (eye worm) calcium channel 0.008 0.0032 0.0188
Mycobacterium ulcerans beta-lactamase 0.04 0.0259 0.0519
Loa Loa (eye worm) hypothetical protein 0.0148 0.008 0.0471
Entamoeba histolytica myo-inositol monophosphatase, putative 0.03 0.0188 0.2647
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0794
Brugia malayi intermediate filament protein 0.0168 0.0095 0.0556
Trypanosoma cruzi casein kinase, putative 0.0157 0.0087 0.1981
Onchocerca volvulus 0.0046 0.0008 0.0056
Loa Loa (eye worm) hypothetical protein 0.042 0.0273 0.1609
Loa Loa (eye worm) hypothetical protein 0.0721 0.0487 0.2872
Echinococcus granulosus Nuclear hormone receptor HR96 0.0063 0.002 0.0077
Loa Loa (eye worm) fibroinase 0.0051 0.0011 0.0064
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0249 0.0152 0.0591
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.0026 0.0026
Echinococcus multilocularis neuroglian 0.0049 0.001 0.0009
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0107 0.0052 0.1192
Schistosoma mansoni netrin receptor unc5 0.01 0.0046 0.0179
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0119
Brugia malayi Death domain containing protein 0.01 0.0046 0.027
Schistosoma mansoni lipoxygenase 0.0039 0.0003 0.001
Echinococcus granulosus lysine specific demethylase 6a 0.0053 0.0013 0.0048
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0123 0.0063 0.0123
Brugia malayi Steroid receptor seven-up type 2 0.0134 0.0071 0.0413
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0033 0.0033
Echinococcus granulosus casein kinase I delta 0.0157 0.0087 0.0338
Echinococcus granulosus arachidonate 5 lipoxygenase 0.011 0.0053 0.0206
Echinococcus multilocularis aldo keto reductase 0.0062 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0038 0.0003 0.0007
Onchocerca volvulus 0.0044 0.0006 0.0043
Schistosoma mansoni DNA ligase IV 0.0057 0.0016 0.0061
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0292 0.0183 0.4332
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0105 0.005 0.107
Toxoplasma gondii PHD-finger domain-containing protein 0.0038 0.0003 0.0056
Brugia malayi Glycosyl hydrolases family 31 protein 0.0324 0.0205 0.1207
Trypanosoma cruzi casein kinase, putative 0.0157 0.0087 0.1981
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0216 0.0128 0.05
Echinococcus multilocularis replication factor c subunit 1 0.0058 0.0016 0.0016
Brugia malayi AF-10 protein 0.0038 0.0003 0.0011
Brugia malayi nuclear hormone receptor 0.0134 0.0071 0.0413
Echinococcus multilocularis lysosomal alpha glucosidase 0.0324 0.0205 0.0204
Brugia malayi Hexokinase family protein 0.0077 0.003 0.0174
Brugia malayi MH2 domain containing protein 0.0115 0.0057 0.0334
Loa Loa (eye worm) hypothetical protein 0.0072 0.0027 0.0153
Schistosoma mansoni coup transcription factor 0.0134 0.0071 0.0273
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.044
Loa Loa (eye worm) patched family protein 0.0063 0.002 0.0114
Echinococcus granulosus lamin dm0 0.0168 0.0095 0.0368
Echinococcus granulosus hypothetical protein 0.0121 0.0061 0.0236
Mycobacterium tuberculosis Conserved protein 0.04 0.0259 0.051
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0011 0.0147
Loa Loa (eye worm) hypothetical protein 0.0168 0.0094 0.0554
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0131 0.0068 0.1605
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0029 0.0109
Loa Loa (eye worm) nuclear receptor NHR-67 0.0063 0.002 0.0116
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Brugia malayi Nuclear hormone receptor E75 0.0063 0.002 0.0116
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.006 0.0018 0.0069
Brugia malayi glutathione reductase 0.0364 0.0234 0.1377
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0034 0.0033
Brugia malayi protein C24B5.3 0.0063 0.002 0.0114
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.008 0.0032 0.0122
Brugia malayi exodeoxyribonuclease III family protein 0.0169 0.0096 0.0561
Schistosoma mansoni glutaminase 0.054 0.0359 0.14
Loa Loa (eye worm) oxidoreductase 0.0062 0.002 0.0113
Brugia malayi conserved hypotetical protein 0.0063 0.002 0.0116
Brugia malayi nuclear receptor RXR 0.0063 0.002 0.0116
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.04 0.0259 0.1528
Onchocerca volvulus Netrin receptor homolog 0.01 0.0046 0.0338
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0126 0.0065 0.0118
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0174 0.0099 0.0098
Echinococcus granulosus cdgsh iron sulfur domain containing protein 0.048 0.0316 0.1233
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0008 0.0029
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0092 0.004 0.0235
Schistosoma mansoni amine oxidase 0.0044 0.0006 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Loa Loa (eye worm) hypothetical protein 0.0314 0.0198 0.1164
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0978 0.0669 0.0668
Trypanosoma brucei importin beta-1 subunit, putative 0.0207 0.0122 0.2908
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.008 0.0032 0.0188
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0016 0.0229
Echinococcus granulosus microtubule associated protein 2 0.3641 0.2557 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0444 0.029 0.0289
Echinococcus multilocularis lysosomal alpha glucosidase 0.0324 0.0205 0.0204
Trypanosoma brucei poly(adp-ribose) polymerase 0.0095 0.0043 0.0987
Onchocerca volvulus 0.0249 0.0152 0.1118
Brugia malayi SWIRM domain containing protein 0.0044 0.0006 0.0034
Giardia lamblia DINP protein human, muc B family 0.0099 0.0045 0.0874
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0095 0.0043 0.0042
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0123 0.0063 0.0243
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0058 0.0016 0.0215
Plasmodium vivax importin-beta 2, putative 0.0207 0.0122 0.3371
Schistosoma mansoni voltage-gated cation channel 0.008 0.0032 0.0124
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0079 0.0031 0.012
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.009 0.0039 0.0151
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0126 0.0065 0.038
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0016 0.0059
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0197 0.0115 0.267
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0709
Toxoplasma gondii hexokinase 0.0077 0.003 0.083
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.0026 0.0359
Loa Loa (eye worm) hypothetical protein 0.0123 0.0063 0.0367
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Entamoeba histolytica protein kinase domain containing protein 0.0197 0.0115 0.1616
Entamoeba histolytica phosphofructokinase, putative 0.0105 0.005 0.0691
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.0071 0.0026 0.0149
Echinococcus multilocularis importin 5 0.0039 0.0003 0.0003
Echinococcus multilocularis hexokinase type 2 0.0077 0.003 0.0029
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.006 0.1326
Trypanosoma brucei casein kinase I, isoform 2 0.0157 0.0087 0.2056
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.144
Mycobacterium ulcerans aldehyde dehydrogenase 0.0123 0.0062 0.0122
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Brugia malayi isocitrate dehydrogenase 0.0083 0.0034 0.0198
Echinococcus granulosus Niemann Pick C1 protein 0.1034 0.0708 0.2768
Echinococcus granulosus beta LACTamase domain containing family member 0.04 0.0259 0.1012
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0123 0.0063 0.1753
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0083 0.0034 0.0131
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Onchocerca volvulus 0.0207 0.0122 0.0899
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0063 0.002 0.0077
Mycobacterium tuberculosis Conserved hypothetical protein 0.0325 0.0206 0.0403
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.002 0.0138
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0528 0.035 0.2064
Echinococcus granulosus peregrin 0.0136 0.0072 0.0277
Loa Loa (eye worm) hypothetical protein 0.0168 0.0095 0.0556
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.0083 0.1885
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.002 0.0145
Onchocerca volvulus Hexokinase homolog 0.0048 0.001 0.0067
Schistosoma mansoni gabp alpha 0.0075 0.0029 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.04 0.0259 0.051
Toxoplasma gondii hypothetical protein 0.0035 0.0001 0.0002
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0169 0.0096 0.018
Echinococcus granulosus FTZ F1 alpha 0.0134 0.0071 0.0273
Loa Loa (eye worm) thioredoxin reductase 0.0364 0.0234 0.1377
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0025 0.0552
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0068 0.0024 0.0023
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0051 0.0011 0.0077
Onchocerca volvulus 0.0051 0.0011 0.008
Echinococcus granulosus twitchin 0.0055 0.0014 0.0053
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0448 0.0293 0.1144
Plasmodium falciparum protoporphyrinogen oxidase 0.0044 0.0006 0.0091
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0126 0.0065 0.144
Trypanosoma brucei pyruvate kinase 1 0.0352 0.0225 0.5412
Entamoeba histolytica protein kinase domain containing protein 0.0197 0.0115 0.1616
Mycobacterium leprae PROBABLE AMINOPEPTIDASE PEPC 0.0072 0.0027 0.0324
Brugia malayi Patched protein homolog 1 0.0063 0.002 0.0114
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0184 0.0106 0.0623
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0126 0.0065 0.0252
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.042 0.0273 0.1609
Schistosoma mansoni survival motor neuron protein 0.0494 0.0326 0.1272
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0197 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Plasmodium vivax pyruvate kinase 2, putative 0.018 0.0103 0.2844
Trichomonas vaginalis D-aminoacylase, putative 0.04 0.0259 0.1912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Giardia lamblia Aldose reductase 0.0062 0.002 0.0118
Echinococcus multilocularis pyruvate kinase 0.018 0.0103 0.0103
Giardia lamblia Kinase, CMGC GSK 0.0197 0.0115 0.293
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0269 0.0166 0.2557
Brugia malayi Bm-MIF-1, identical 0.0167 0.0094 0.0549
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Echinococcus multilocularis 6 phosphofructokinase 0.0105 0.005 0.0049
Echinococcus granulosus casein kinase I alpha 0.0157 0.0087 0.0338
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0249 0.0152 0.4257
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0126 0.0065 0.0127
Echinococcus granulosus lamin 0.0168 0.0095 0.0368
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0617 0.0413 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0013 0.0012
Trypanosoma brucei unspecified product 0.0113 0.0055 0.1287
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.009 0.0039 0.0039
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0016 0.0059
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.042 0.0273 0.0547
Echinococcus granulosus jumonji domain containing 1A 0.0053 0.0013 0.0048
Echinococcus granulosus casein kinase I alpha 0.0157 0.0087 0.0338
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Entamoeba histolytica aldose reductase, putative 0.0062 0.002 0.0264
Echinococcus granulosus lysine specific demethylase 5A 0.0214 0.0127 0.0495
Trypanosoma brucei importin beta-1 subunit, putative 0.0207 0.0122 0.2908
Trypanosoma brucei phosphoglycerate kinase 0.0536 0.0356 0.8598
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0037 0.0753
Treponema pallidum exodeoxyribonuclease (exoA) 0.0169 0.0096 0.2338
Loa Loa (eye worm) ctsf protein 0.0051 0.0011 0.0064
Brugia malayi jmjC domain containing protein 0.0053 0.0013 0.0073
Brugia malayi hypothetical protein 0.0071 0.0026 0.0148
Brugia malayi jmjC domain containing protein 0.044 0.0287 0.1692
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0831 0.0565 0.1126
Onchocerca volvulus 0.0036 0.0001 0.0003
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0134 0.0071 0.0273
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0002 0.0001
Trichomonas vaginalis D-aminoacylase, putative 0.04 0.0259 0.1912
Echinococcus granulosus mothers against decapentaplegic 5 0.0115 0.0057 0.0221
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0092 0.004 0.0156
Brugia malayi Bromodomain containing protein 0.0089 0.0039 0.0224
Schistosoma mansoni pyruvate kinase 0.018 0.0103 0.0402
Toxoplasma gondii Erv1 / Alr family protein 0.0107 0.0052 0.1434
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0071 0.0026 0.0025
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0053 0.0013 0.0349
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0126 0.0065 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Echinococcus multilocularis Immunoglobulin 0.0049 0.001 0.0009
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0063 0.002 0.0145
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0013 0.0073
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0123 0.0063 0.0123
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0031 0.0397
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0126 0.0065 0.1753
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.04 0.0259 0.1012
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0327 0.0207 0.0808
Schistosoma mansoni amine oxidase 0.0044 0.0006 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0292 0.0183 0.442
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0053 0.0013 0.0161
Brugia malayi Aspartyl aminopeptidase 0.0072 0.0027 0.0153
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0134 0.0071 0.007
Loa Loa (eye worm) hypothetical protein 0.0057 0.0016 0.0092
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0536 0.0356 0.5597
Leishmania major cathepsin L-like protease 0.0193 0.0112 0.2719
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0026 0.0492
Brugia malayi photoreceptor-specific nuclear receptor 0.0134 0.0071 0.0413
Loa Loa (eye worm) hypothetical protein 0.0071 0.0026 0.0148
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0127 0.0065 0.1526
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0131 0.0068 0.1552
Brugia malayi Immunoglobulin I-set domain containing protein 0.01 0.0046 0.027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus multilocularis dnaJ subfamily B 0.1665 0.1156 0.1156
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0013 0.0071
Trichomonas vaginalis glutathione reductase, putative 0.0126 0.0065 0.0473
Brugia malayi hypothetical protein 0.0063 0.002 0.0114
Schistosoma mansoni alpha-glucosidase 0.0279 0.0173 0.0675
Schistosoma mansoni ran 0.0131 0.0068 0.0265
Onchocerca volvulus 0.0062 0.002 0.0141
Echinococcus granulosus nibrin 0.0057 0.0016 0.0061
Onchocerca volvulus 0.0063 0.002 0.0143
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0013 0.0047
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0016 0.0426
Loa Loa (eye worm) G protein alpha subunit 3 0.0036 0.0001 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0083 0.0034 0.0033
Echinococcus granulosus thioredoxin glutathione reductase 0.0365 0.0234 0.0915
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0123 0.0063 0.0123
Mycobacterium tuberculosis Probable aminopeptidase PepC 0.0072 0.0027 0.0041
Echinococcus multilocularis aspartyl aminopeptidase 0.0072 0.0027 0.0026
Brugia malayi hypothetical protein 0.0063 0.002 0.0114
Trypanosoma cruzi hexokinase, putative 0.0077 0.003 0.0581
Echinococcus multilocularis JmjC domain containing protein 4 0.0053 0.0013 0.0012
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Schistosoma mansoni single-minded 0.005 0.0011 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0839 0.057 0.057
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0324 0.0205 0.1207
Onchocerca volvulus Bile acid receptor homolog 0.0134 0.0071 0.0517
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.009 0.0039 0.0229
Mycobacterium ulcerans lipase LipD 0.04 0.0259 0.0519
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0034 0.0825
Onchocerca volvulus 0.0037 0.0002 0.0008
Echinococcus multilocularis casein kinase I delta 0.0157 0.0087 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0013 0.0073
Schistosoma mansoni hexokinase 0.0077 0.003 0.0115
Loa Loa (eye worm) hypothetical protein 0.0314 0.0198 0.1164
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0057 0.0016 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Leishmania major cathepsin L-like protease 0.0193 0.0112 0.2719
Brugia malayi RNA, U transporter 1 0.0588 0.0392 0.2312
Loa Loa (eye worm) oxidoreductase 0.0062 0.002 0.0113
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0036 0.0001 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0037 0.0753
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0831 0.0565 0.8946
Leishmania major trypanothione reductase 0.0364 0.0234 0.5657
Echinococcus granulosus hexokinase 0.0077 0.003 0.0115
Schistosoma mansoni hypothetical protein 0.0428 0.0279 0.1087
Loa Loa (eye worm) hypothetical protein 0.0134 0.0071 0.0413
Plasmodium vivax JmjC domain containing protein 0.0053 0.0013 0.0277
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.0176 0.2469
Plasmodium vivax hypothetical protein, conserved 0.0044 0.0006 0.0091
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0036 0.0001 0.0002
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0025 0.0552
Plasmodium falciparum macrophage migration inhibitory factor 0.0167 0.0094 0.2566
Schistosoma mansoni pyruvate kinase 0.0352 0.0225 0.0877
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.006 0.1407
Trichomonas vaginalis ran, putative 0.0131 0.0068 0.0499
Plasmodium falciparum ataxin-2 like protein, putative 0.0177 0.0101 0.278
Brugia malayi PHD-finger family protein 0.0054 0.0014 0.0076
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0031 0.0794
Plasmodium falciparum protein serine/threonine kinase-1 0.0127 0.0065 0.176
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0123 0.0063 0.0874
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Echinococcus granulosus histone acetyltransferase KAT2B 0.0173 0.0098 0.0382
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.002 0.002
Trypanosoma brucei hexokinase, putative 0.0077 0.003 0.0669
Giardia lamblia NADH oxidase lateral transfer candidate 0.0126 0.0065 0.1449
Mycobacterium ulcerans hypothetical protein 0.04 0.0259 0.0519
Leishmania major 4-coumarate:coa ligase-like protein 0.042 0.0273 0.6607
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.0176 0.2469
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0016 0.0113
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0063 0.002 0.0116
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0036 0.0001 0.0002
Brugia malayi nuclear receptor NHR-67 0.0063 0.002 0.0116
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0099 0.0045 0.1099
Echinococcus multilocularis netrin receptor unc 5 0.01 0.0046 0.0046
Brugia malayi follicle stimulating hormone receptor 0.0528 0.035 0.2064
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0134 0.0071 0.007
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0269 0.0166 0.0322
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0008 0.0029
Mycobacterium tuberculosis Probable esterase LipL 0.04 0.0259 0.051
Schistosoma mansoni hypothetical protein 0.0117 0.0058 0.0226
Echinococcus multilocularis peregrin 0.0136 0.0072 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Echinococcus multilocularis voltage dependent calcium channel 0.008 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus granulosus mothers against decapentaplegic 6 0.0051 0.0012 0.0044
Plasmodium vivax hexokinase, putative 0.0077 0.003 0.0762
Toxoplasma gondii LsmAD domain-containing protein 0.0177 0.0101 0.2833
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0216 0.0128 0.0128
Mycobacterium tuberculosis Probable dehydrogenase 0.0831 0.0565 0.1126
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0071 0.0026 0.0098
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0123 0.0063 0.1387
Onchocerca volvulus Protein patched homolog 0.0063 0.002 0.0143
Loa Loa (eye worm) steroid hormone receptor 0.0134 0.0071 0.0413
Trichomonas vaginalis hypothetical protein 0.0039 0.0003 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0039 0.0003 0.001
Schistosoma mansoni phosphatidylserine receptor 0.0053 0.0013 0.0048
Echinococcus multilocularis voltage dependent calcium channel 0.008 0.0032 0.0032
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.008 0.0032 0.0124
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.044 0.0287 0.0287
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0008 0.0029
Schistosoma mansoni nuclear receptor 0.0063 0.002 0.0077
Loa Loa (eye worm) patched family protein 0.0063 0.002 0.0114
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0197 0.0115 0.0677
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0115 0.0057 0.0057
Mycobacterium ulcerans hypothetical protein 0.0325 0.0206 0.0412
Echinococcus granulosus roundabout 2 0.0049 0.001 0.0037
Loa Loa (eye worm) hypothetical protein 0.0082 0.0033 0.0194
Brugia malayi PAS domain containing protein 0.005 0.0011 0.0061
Echinococcus multilocularis beta LACTamase domain containing family member 0.04 0.0259 0.0259
Echinococcus granulosus voltage dependent calcium channel 0.008 0.0032 0.0124
Leishmania major DNA polymerase eta, putative 0.0092 0.004 0.098
Echinococcus granulosus nuclear receptor nhr 48 0.0063 0.002 0.0077
Loa Loa (eye worm) nuclear factor I 0.0064 0.0021 0.0118
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0168 0.0095 0.0556
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Toxoplasma gondii patched family protein 0.0063 0.002 0.0545
Brugia malayi Importin beta-1 subunit 0.0207 0.0122 0.0717
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0082 0.0034 0.013
Onchocerca volvulus 0.0077 0.003 0.0217
Schistosoma mansoni ap endonuclease 0.0169 0.0096 0.0371
Toxoplasma gondii PHD-finger domain-containing protein 0.0117 0.0058 0.1627
Toxoplasma gondii hypothetical protein 0.01 0.0046 0.1281
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.008 0.0032 0.0032
Brugia malayi Augmenter of liver regeneration 0.0107 0.0052 0.03
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0123 0.0063 0.0062
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.0026 0.0492
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.008 0.0032 0.0124
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Onchocerca volvulus Cathepsin L homolog 0.0051 0.0011 0.008
Loa Loa (eye worm) hypothetical protein 0.01 0.0046 0.027
Echinococcus multilocularis phosphoglycerate kinase 1 0.0536 0.0356 0.0355
Schistosoma mansoni chromosome transmission fidelity factor 0.0058 0.0016 0.0061
Echinococcus multilocularis Ankyrin 0.01 0.0047 0.0046
Mycobacterium tuberculosis Probable reductase 0.0831 0.0565 0.1126
Schistosoma mansoni aldehyde dehydrogenase 0.0123 0.0062 0.0242
Brugia malayi Uncharacterized hematopoietic stem/progenitor cells protein MDS029 0.0204 0.012 0.0706
Plasmodium falciparum cysteine proteinase falcipain 3 0.0051 0.0011 0.0233
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0197 0.0115 0.0449
Schistosoma mansoni hypothetical protein 0.0327 0.0207 0.0808
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0123 0.0063 0.1753
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0079 0.0031 0.0031
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Echinococcus multilocularis 0.0044 0.0006 0.0006
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0107 0.0052 0.1109
Plasmodium vivax vivapain-2 0.0051 0.0011 0.0233
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0352 0.0225 0.1324
Loa Loa (eye worm) Smad1 0.0115 0.0057 0.0334
Brugia malayi DnaJ domain containing protein 0.0185 0.0107 0.0627
Mycobacterium ulcerans hypothetical protein 0.042 0.0273 0.0547
Brugia malayi hypothetical protein 0.0063 0.002 0.0114
Onchocerca volvulus 0.0187 0.0108 0.0796
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0134 0.0071 0.0413
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0008 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0296 0.0186 0.0362
Schistosoma mansoni lipoxygenase 0.011 0.0053 0.0206
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0282 0.0175 0.0684
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0296 0.0186 0.0362
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0123 0.0063 0.0114
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0924 0.063 0.1258
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.021 0.0124 0.2897
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0176 0.1293
Trypanosoma cruzi DNA polymerase kappa, putative 0.012 0.006 0.1326
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.005 0.0362
Echinococcus multilocularis nibrin 0.0057 0.0016 0.0016
Brugia malayi hypoxia-induced factor 1 0.0155 0.0085 0.05
Echinococcus multilocularis protein dispatched 1 0.0506 0.0334 0.0334
Echinococcus multilocularis tar DNA binding protein 0.0125 0.0064 0.0064
Plasmodium vivax vivapain-2 0.0051 0.0011 0.0233
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0123 0.0063 0.0123
Loa Loa (eye worm) acetyltransferase 0.0577 0.0385 0.2269
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0107 0.0052 0.1371
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0012 0.0067
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Trypanosoma cruzi PAB1-binding protein , putative 0.0177 0.0101 0.233
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Schistosoma mansoni ap endonuclease 0.0169 0.0096 0.0371
Schistosoma mansoni protein phosphatase 2C 0.0053 0.0013 0.0048
Loa Loa (eye worm) oxidoreductase 0.0062 0.002 0.0113
Loa Loa (eye worm) hypothetical protein 0.0081 0.0033 0.0192
Trypanosoma brucei DNA polymerase IV, putative 0.0113 0.0055 0.1287
Brugia malayi latrophilin 2 splice variant baaae 0.0706 0.0476 0.2807
Loa Loa (eye worm) hypothetical protein 0.0064 0.0021 0.0119
Schistosoma mansoni topbp1 0.0057 0.0016 0.0061
Brugia malayi nuclear hormone receptor 0.0063 0.002 0.0116
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0107 0.0052 0.0199
Echinococcus multilocularis nuclear receptor nhr 48 0.0063 0.002 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.042 0.0273 0.3845
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0051 0.0011 0.0077
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0126 0.0065 0.1677
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0157 0.0087 0.051
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0064 0.0249
Echinococcus multilocularis smad 0.0115 0.0057 0.0057
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0036 0.0001 0.0002
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0057 0.0016 0.0092
Loa Loa (eye worm) hypothetical protein 0.042 0.0273 0.1609
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Loa Loa (eye worm) hypothetical protein 0.0177 0.0101 0.0594
Leishmania major cathepsin L-like protease 0.0051 0.0011 0.0276
Brugia malayi Nuclear hormone receptor-like 1 0.0134 0.0071 0.0413
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Echinococcus granulosus pyruvate kinase 0.018 0.0103 0.0402
Trypanosoma brucei hypothetical protein, conserved 0.04 0.0259 0.6254
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0056 0.0015 0.0416
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0036 0.0001 0.0002
Onchocerca volvulus 0.0057 0.0016 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0134 0.0071 0.0413
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0169 0.0096 0.0189
Entamoeba histolytica phosphoglycerate kinase, putative 0.0536 0.0356 0.5013
Echinococcus granulosus dual specificity 0.0184 0.0106 0.0413
Loa Loa (eye worm) histone methyltransferase 0.0073 0.0027 0.0157
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Echinococcus multilocularis 0.0121 0.0061 0.006
Echinococcus multilocularis roundabout 2 0.0049 0.001 0.0009
Brugia malayi MAP kinase sur-1 0.0057 0.0016 0.0089
Echinococcus multilocularis hexokinase 0.0077 0.003 0.0029
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0839 0.057 0.3365
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0167 0.0094 0.0685
Mycobacterium tuberculosis Probable oxidoreductase 0.0924 0.063 0.1258
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0134 0.0071 0.0273
Echinococcus multilocularis dna polymerase eta 0.0092 0.004 0.004
Onchocerca volvulus 0.0127 0.0065 0.048
Loa Loa (eye worm) hypothetical protein 0.0072 0.0027 0.0153
Echinococcus granulosus Ankyrin 0.01 0.0047 0.018
Plasmodium falciparum casein kinase 1 0.0157 0.0087 0.2377
Echinococcus granulosus lysine specific histone demethylase 1A 0.0044 0.0006 0.0023
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0123 0.0063 0.1692
Mycobacterium ulcerans DNA polymerase IV 0.012 0.006 0.0118
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0831 0.0565 0.1126
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0123 0.0063 0.0123
Echinococcus granulosus aldehyde reductase 0.0044 0.0007 0.0024
Brugia malayi hypothetical protein 0.0057 0.0016 0.0092
Loa Loa (eye worm) patched family protein 0.0063 0.002 0.0114
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1706 0.1185 0.6996
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0044 0.0006 0.0006
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0016 0.0109
Onchocerca volvulus 0.0048 0.001 0.0067
Schistosoma mansoni hypothetical protein 0.1665 0.1156 0.452
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0031 0.0862
Schistosoma mansoni pol-related 0.0062 0.002 0.0075
Schistosoma mansoni inositol monophosphatase 0.03 0.0188 0.0734
Schistosoma mansoni CDGSH-type Zn finger-containing protein-like protein 0.0509 0.0336 0.1313
Trypanosoma brucei DNA polymerase IV, putative 0.012 0.006 0.1407
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0536 0.0356 0.8585
Leishmania major hypothetical protein, conserved 0.04 0.0259 0.6277
Onchocerca volvulus 0.0063 0.002 0.0143
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0036 0.0001 0.0002
Echinococcus granulosus pyruvate kinase 0.0352 0.0225 0.0877
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0536 0.0356 0.0704
Brugia malayi mbt repeat family protein 0.0046 0.0008 0.0044
Echinococcus multilocularis dual specificity protein kinase clk2 0.0127 0.0065 0.0065
Onchocerca volvulus Huntingtin homolog 0.0148 0.008 0.059
Brugia malayi nuclear receptor NHR-88 0.0134 0.0071 0.0413
Onchocerca volvulus 0.0036 0.0001 0.0003
Echinococcus granulosus defective proboscis extension response 0.0049 0.001 0.0037
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0044 0.0006 0.0091
Loa Loa (eye worm) nuclear hormone receptor 0.0063 0.002 0.0116
Schistosoma mansoni hypothetical protein 0.1221 0.0842 0.3289
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0011 0.0042
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0134 0.0071 0.0273
Brugia malayi Patched related family protein 4 0.0063 0.002 0.0114
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.021 0.0124 0.3007
Loa Loa (eye worm) hypothetical protein 0.0178 0.0102 0.0598
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.01 0.0046 0.027
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0123 0.0063 0.1387
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0831 0.0565 0.1126
Entamoeba histolytica hypothetical protein 0.0168 0.0094 0.1318
Loa Loa (eye worm) hypothetical protein 0.0543 0.0361 0.2127
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0049 0.001 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0051 0.0011 0.0233
Brugia malayi ecdysone receptor 0.0063 0.002 0.0116
Echinococcus granulosus lysosomal alpha glucosidase 0.0324 0.0205 0.08
Echinococcus multilocularis inositol monophosphatase 1 0.03 0.0188 0.0188
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0062 0.002 0.0113
Loa Loa (eye worm) hypothetical protein 0.0044 0.0006 0.0034
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Loa Loa (eye worm) hypothetical protein 0.008 0.0032 0.0188
Loa Loa (eye worm) hypothetical protein 0.0036 0.0001 0.0002
Leishmania major protein kinase, putative 0.0127 0.0065 0.1578
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0197 0.0115 0.0449
Echinococcus multilocularis pyruvate kinase 0.0352 0.0225 0.0224
Leishmania major pyruvate kinase 0.0352 0.0225 0.544
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0053 0.0013 0.0161
Trypanosoma brucei unspecified product 0.0063 0.002 0.0432
Loa Loa (eye worm) pyruvate kinase-PB 0.0245 0.0149 0.0878
Loa Loa (eye worm) hypothetical protein 0.1032 0.0708 0.4175
Loa Loa (eye worm) hypothetical protein 0.009 0.0039 0.0228
Echinococcus multilocularis poly (ADP ribose) polymerase 0.004 0.0004 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.1691 0.1174 0.6931
Schistosoma mansoni nuclear hormone receptor 0.0063 0.002 0.0077
Echinococcus multilocularis protoporphyrinogen oxidase 0.0044 0.0006 0.0006
Trypanosoma cruzi FHA domain containing protein, putative 0.0057 0.0016 0.0242
Brugia malayi glucose-6-phosphate dehydrogenase 0.009 0.0039 0.0229
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.007 0.0025 0.0025
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Loa Loa (eye worm) PHD-finger family protein 0.004 0.0004 0.002
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0173 0.0098 0.2749
Loa Loa (eye worm) hypothetical protein 0.0314 0.0198 0.1164
Toxoplasma gondii isocitrate dehydrogenase 0.0083 0.0034 0.0944
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0087 0.0338
Loa Loa (eye worm) hypothetical protein 0.0121 0.0061 0.0356
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0034 0.0033
Brugia malayi nuclear hormone receptor family member odr-7 0.0063 0.002 0.0116
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0126 0.0065 0.1436
Plasmodium falciparum glutathione reductase 0.0126 0.0065 0.1753
Leishmania major ATP-dependent phosphofructokinase 0.0105 0.005 0.1208
Mycobacterium tuberculosis Probable conserved lipoprotein 0.04 0.0259 0.051
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0083 0.0034 0.0768
Brugia malayi hypothetical protein 0.0044 0.0006 0.0034
Echinococcus multilocularis muscleblind protein 1 0.0148 0.0081 0.008
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0131 0.0068 0.0068
Loa Loa (eye worm) inositol-1 0.03 0.0188 0.1108
Brugia malayi nuclear hormone receptor family member nhr-6 0.0063 0.002 0.0116
Loa Loa (eye worm) hypothetical protein 0.0036 0.0001 0.0002
Entamoeba histolytica aspartyl aminopeptidase, putative 0.0072 0.0027 0.0362
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0123 0.0063 0.0123
Schistosoma mansoni cell adhesion molecule 0.0049 0.001 0.0037
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.03 0.0188 0.5285
Schistosoma mansoni acetyl-CoA synthetase 0.0123 0.0063 0.0243
Mycobacterium ulcerans acyl-CoA synthetase 0.042 0.0273 0.0547
Echinococcus multilocularis tumor protein p63 0.3458 0.2427 0.2427
Onchocerca volvulus 0.0077 0.003 0.0217
Brugia malayi Cathepsin L-like precursor 0.0051 0.0011 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0127 0.0065 0.1446
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0123 0.0063 0.0123
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0169 0.0096 0.2622
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0173 0.0098 0.2749
Giardia lamblia PHD finger protein 15 0.0117 0.0058 0.1254
Loa Loa (eye worm) hypothetical protein 0.0056 0.0016 0.0088
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.1034 0.0708 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0051 0.0011 0.0011
Schistosoma mansoni lamin 0.0168 0.0095 0.0368
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0282 0.0175 0.0684
Brugia malayi kap beta 3 protein 0.0039 0.0003 0.0015
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0098 0.0045 0.1192
Onchocerca volvulus 0.0051 0.0011 0.008
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0123 0.0063 0.1387
Onchocerca volvulus 0.0063 0.002 0.0145
Trypanosoma brucei DNA polymerase kappa, putative 0.007 0.0025 0.0552
Echinococcus granulosus aspartyl aminopeptidase 0.0072 0.0027 0.0102
Echinococcus granulosus expressed conserved protein 0.0971 0.0664 0.2594
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0062 0.002 0.0019
Schistosoma mansoni smad1 5 8 and 0.0115 0.0057 0.0221
Loa Loa (eye worm) hypothetical protein 0.0245 0.0149 0.0878
Loa Loa (eye worm) hypothetical protein 0.0123 0.0063 0.0367
Brugia malayi Smad1 0.0115 0.0057 0.0334
Onchocerca volvulus 0.0062 0.002 0.0141
Plasmodium falciparum phd finger protein, putative 0.0117 0.0058 0.1565
Leishmania major hypothetical protein, conserved 0.0053 0.0013 0.0314
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0173 0.0098 0.0719
Brugia malayi Protein kinase domain containing protein 0.0184 0.0106 0.0623
Echinococcus granulosus poly (ADP ribose) polymerase 0.0054 0.0014 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0105 0.005 0.0362
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0049 0.001 0.0037
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0062 0.002 0.0138
Brugia malayi G-protein alpha subunit 0.0036 0.0001 0.0002
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0123 0.0063 0.0114
Loa Loa (eye worm) oxidoreductase 0.0123 0.0063 0.0367
Onchocerca volvulus 0.0168 0.0095 0.0697
Schistosoma mansoni cpg binding protein 0.0207 0.0122 0.0475
Echinococcus granulosus nuclear factor of activated T cells 5 0.0978 0.0669 0.2614
Echinococcus multilocularis dnaJ subfamily C 6 0.0185 0.0107 0.0106
Loa Loa (eye worm) hypothetical protein 0.0095 0.0043 0.0251
Brugia malayi AMP-binding enzyme family protein 0.0123 0.0063 0.0367
Plasmodium falciparum glycogen synthase kinase 3 0.0197 0.0115 0.3181
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0053 0.0013 0.0253
Loa Loa (eye worm) hypothetical protein 0.0078 0.0031 0.0179
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0126 0.0065 0.0064
Echinococcus multilocularis muscleblind protein 0.0148 0.0081 0.008
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0011 0.0042
Trichomonas vaginalis antibiotic synthetase, putative 0.0123 0.0063 0.0458
Echinococcus multilocularis microtubule associated protein 2 0.3641 0.2557 0.2557
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0134 0.0071 0.0413
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0016 0.0229
Schistosoma mansoni thyroid hormone receptor 0.0264 0.0162 0.0632
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0106 0.005 0.1084
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Trichomonas vaginalis D-aminoacylase, putative 0.04 0.0259 0.1912
Trichomonas vaginalis esterase, putative 0.04 0.0259 0.1912
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0051 0.0011 0.0011
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.03 0.0188 0.4555
Echinococcus multilocularis jumonji domain containing protein 0.0163 0.0091 0.009
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0087 0.0037 0.0753
Schistosoma mansoni phd/f-box containing protein 0.0053 0.0013 0.0048
Leishmania major mitochondrial DNA polymerase beta 0.0617 0.0413 1
Echinococcus granulosus pyruvate kinase 0.018 0.0103 0.0402
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0134 0.0071 0.0413
Loa Loa (eye worm) jmjC domain-containing protein 0.0053 0.0013 0.0073
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0026 0.0188
Mycobacterium ulcerans phosphoglycerate kinase 0.0536 0.0356 0.0713
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0327 0.0207 0.0206
Schistosoma mansoni Smad4 0.0115 0.0057 0.0221
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Leishmania major 4-coumarate:coa ligase-like protein 0.042 0.0273 0.6607
Toxoplasma gondii ABC1 family protein 0.04 0.0259 0.7288
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Brugia malayi AMP-binding enzyme family protein 0.042 0.0273 0.1609
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0127 0.0065 0.1446
Giardia lamblia Kinase, CMGC CLK 0.0127 0.0065 0.1456
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0011 0.0123
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0063 0.002 0.002
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0031 0.0709
Loa Loa (eye worm) MH1 domain-containing protein 0.0115 0.0057 0.0334
Brugia malayi Papain family cysteine protease containing protein 0.0051 0.0011 0.0064
Trichomonas vaginalis CMGC family protein kinase 0.0197 0.0115 0.0846
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0131 0.0068 0.1852
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.009 0.0039 0.0151
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0231 0.0139 0.3907
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0016 0.0242
Trichomonas vaginalis macrophage migration inhibitory factor, mif, putative 0.0167 0.0094 0.0685
Trypanosoma brucei aldo-keto reductase, putative 0.0062 0.002 0.0417
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0168 0.0094 0.069
Onchocerca volvulus 0.0063 0.002 0.0143
Echinococcus multilocularis geminin 0.1221 0.0842 0.0841
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0107 0.0052 0.1109
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Trypanosoma brucei DNA polymerase kappa, putative 0.012 0.006 0.1407
Brugia malayi protein C24B5.3 0.0063 0.002 0.0114
Echinococcus granulosus mothers against decapentaplegic 2 0.0051 0.0012 0.0044
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Echinococcus granulosus tar DNA binding protein 0.0125 0.0064 0.0249
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Loa Loa (eye worm) hypothetical protein 0.1034 0.0708 0.418
Echinococcus granulosus casein kinase I delta 0.0157 0.0087 0.0338
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0126 0.0065 0.1573
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0083 0.0034 0.0681
Echinococcus multilocularis Smad4 0.0115 0.0057 0.0057
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0064 0.0249
Plasmodium vivax serine/threonine kinase-1, putative 0.0127 0.0065 0.176
Loa Loa (eye worm) PHD-finger family protein 0.0117 0.0058 0.0341
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0009 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Loa Loa (eye worm) hypothetical protein 0.2423 0.1694 1
Entamoeba histolytica cysteine protease, putative 0.0051 0.0011 0.0147
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0051 0.0012 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0134 0.0071 0.0413
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0123 0.0063 0.0367
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0016 0.0113
Trypanosoma brucei phosphoglycerate kinase 0.0536 0.0356 0.8598
Onchocerca volvulus 0.0134 0.0071 0.0517
Brugia malayi hypothetical protein 0.2423 0.1694 1
Loa Loa (eye worm) hypothetical protein 0.04 0.0259 0.1528
Entamoeba histolytica aminopeptidase, putative 0.0072 0.0027 0.0362
Leishmania major 4-coumarate:coa ligase-like protein 0.042 0.0273 0.6607
Entamoeba histolytica hexokinase 1 0.0077 0.003 0.041
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0114
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0169 0.0096 0.2622
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0169 0.0096 0.1337
Loa Loa (eye worm) hypothetical protein 0.0046 0.0008 0.0044
Brugia malayi nuclear receptor NHR-88 0.0063 0.002 0.0116
Mycobacterium ulcerans acyl-CoA synthetase 0.0123 0.0063 0.0123
Schistosoma mansoni hypothetical protein 0.008 0.0032 0.0122
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0314 0.0198 0.0386
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0036 0.0001 0.0002
Echinococcus multilocularis cysteine protease 0.0051 0.0011 0.0011
Leishmania major hexokinase, putative 0.0077 0.003 0.0727
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.03 0.0188 0.447
Echinococcus multilocularis casein kinase I delta 0.0157 0.0087 0.0086
Plasmodium vivax thioredoxin reductase, putative 0.0364 0.0234 0.6542
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0296 0.0186 0.0362
Trypanosoma brucei hexokinase 0.0077 0.003 0.0669
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.04 0.0259 0.1528
Schistosoma mansoni jumonji domain containing protein 0.0361 0.0231 0.0903
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0123 0.0063 0.0114
Brugia malayi Ets-domain containing protein 0.0075 0.0029 0.0165
Loa Loa (eye worm) hypothetical protein 0.0063 0.002 0.0116
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Schistosoma mansoni thyroid hormone receptor 0.0264 0.0162 0.0632
Brugia malayi Doublecortin family protein 0.0039 0.0003 0.0016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Onchocerca volvulus Pyruvate kinase homolog 0.0352 0.0225 0.1658
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.008 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Entamoeba histolytica casein kinase 1, putative 0.0157 0.0087 0.1215
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0062 0.002 0.0213
Entamoeba histolytica hexokinase 2 0.0077 0.003 0.041
Schistosoma mansoni hypothetical protein 0.0494 0.0326 0.1272
Echinococcus granulosus TGF beta signal transducer SmadC 0.0115 0.0057 0.0221
Trypanosoma brucei protein kinase, putative 0.0057 0.0016 0.032
Trichomonas vaginalis helicase, putative 0.0047 0.0009 0.0057
Echinococcus multilocularis lysine specific demethylase 5A 0.0198 0.0116 0.0115
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0083 0.0034 0.0877
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.042 0.0273 0.0547
Echinococcus multilocularis RUN 0.0039 0.0003 0.0003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0134 0.0071 0.0413
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0127 0.0065 0.0381
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.009 0.0039 0.0039
Brugia malayi jmjC domain containing protein 0.0053 0.0013 0.0073
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0036 0.0001 0.0002
Loa Loa (eye worm) DR-78 0.0063 0.002 0.0116
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.008 0.0032 0.0124
Schistosoma mansoni hypothetical protein 0.0327 0.0207 0.0808
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0123 0.0063 0.1468
Brugia malayi MH1 domain containing protein 0.0064 0.0021 0.0118
Schistosoma mansoni hypothetical protein 0.1221 0.0842 0.3289
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0073 0.0027 0.0104
Echinococcus multilocularis phd:f box containing protein 0.0053 0.0013 0.0012
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0126 0.0065 0.1814
Brugia malayi jmjC domain containing protein 0.0214 0.0127 0.0747
Schistosoma mansoni tar DNA-binding protein 0.0125 0.0064 0.0249
Echinococcus multilocularis lamin dm0 0.0168 0.0095 0.0094
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0577 0.0385 0.0384
Trichomonas vaginalis aldo/keto reductase, putative 0.0062 0.002 0.0138
Brugia malayi Pre-SET motif family protein 0.1706 0.1185 0.6996
Echinococcus multilocularis protein patched 0.0444 0.029 0.0289
Echinococcus granulosus transportin 1 0.0039 0.0003 0.001
Brugia malayi hexokinase 0.0077 0.003 0.0174
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0126 0.0065 0.152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0011 0.0077
Loa Loa (eye worm) hypothetical protein 0.0536 0.0356 0.2097
Brugia malayi pyruvate kinase 0.0074 0.0028 0.0162
Brugia malayi beta-lactamase family protein 0.04 0.0259 0.1528
Schistosoma mansoni lamin 0.0168 0.0095 0.0368
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.0026 0.0728
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0044 0.0006 0.0009
Onchocerca volvulus 0.0062 0.002 0.0141
Loa Loa (eye worm) hypothetical protein 0.0053 0.0013 0.0073
Trypanosoma brucei pyruvate kinase 1, putative 0.0352 0.0225 0.5412
Loa Loa (eye worm) hexokinase 0.0077 0.003 0.0174
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0016 0.032
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0053 0.0013 0.0349
Echinococcus granulosus inositol monophosphatase 1 0.03 0.0188 0.0734
Echinococcus granulosus smad 0.0115 0.0057 0.0221
Schistosoma mansoni hypothetical protein 0.0327 0.0207 0.0808
Mycobacterium tuberculosis Probable lipase LipE 0.04 0.0259 0.051
Loa Loa (eye worm) hypothetical protein 0.0282 0.0175 0.1032
Toxoplasma gondii thioredoxin reductase 0.0364 0.0234 0.6567
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0065 0.0253
Schistosoma mansoni hypothetical protein 0.013 0.0067 0.0261
Toxoplasma gondii casein kinase I 0.0157 0.0087 0.2433
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0143 0.0077 0.0076
Brugia malayi casein kinase 1, delta 0.0157 0.0087 0.051
Brugia malayi 6-phosphofructokinase 0.0105 0.005 0.0291
Loa Loa (eye worm) hypothetical protein 0.0207 0.0122 0.0717
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0083 0.0034 0.0681
Trypanosoma brucei protein kinase, putative 0.0197 0.0115 0.2746
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.021 0.0124 0.2897
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0095 0.0043 0.0902
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.009 0.0039 0.0948
Brugia malayi Pyruvate kinase, muscle isozyme 0.0352 0.0225 0.1324
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0039 0.0003 0.0009
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0029 0.0165
Trichomonas vaginalis aldo-keto reductase, putative 0.0062 0.002 0.0138
Loa Loa (eye worm) hypothetical protein 0.0314 0.0198 0.1164
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0134 0.0071 0.0273
Entamoeba histolytica HEAT repeat domain containing protein 0.0039 0.0003 0.0031
Echinococcus multilocularis zinc finger protein 0.0064 0.0021 0.002
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0036 0.0001 0.0002
Trypanosoma cruzi hypothetical protein, conserved 0.0057 0.0016 0.0242
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0016 0.038
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.013 0.0067 0.0067
Echinococcus granulosus dna polymerase eta 0.0092 0.004 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0367 0.0236 0.0235
Echinococcus granulosus expressed protein 0.0036 0.0001 0.0002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0193 0.0112 0.2674
Brugia malayi glutaminase DH11.1 0.054 0.0359 0.2113
Toxoplasma gondii pyruvate kinase PyK1 0.0352 0.0225 0.6315
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0134 0.0071 0.0413
Echinococcus granulosus poly ADP ribose polymerase 1 0.0174 0.0099 0.0383
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0008 0.0008
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0083 0.0034 0.0033
Brugia malayi Bromodomain containing protein 0.0173 0.0098 0.0574
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0123 0.0063 0.0114
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0126 0.0065 0.0127
Loa Loa (eye worm) hypothetical protein 0.0148 0.0081 0.0472
Toxoplasma gondii histone lysine methyltransferase SET1 0.042 0.0273 0.7674
Schistosoma mansoni cpg binding protein 0.0222 0.0133 0.0518
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0184 0.0106 0.2453
Brugia malayi Patched family protein 0.0063 0.002 0.0114
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0083 0.0034 0.0056
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0045 0.0007 0.0119
Plasmodium falciparum JmjC domain-containing protein, putative 0.0053 0.0013 0.0277
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.0026 0.0188
Giardia lamblia Phosphoglycerate kinase 0.0536 0.0356 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0013 0.0071
Loa Loa (eye worm) glutaminase 2 0.054 0.0359 0.2113
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0058 0.0016 0.0113
Entamoeba histolytica Ran family GTPase 0.0131 0.0068 0.0953
Trichomonas vaginalis protein kinase inhibitor, putative 0.0185 0.0107 0.0784
Mycobacterium ulcerans fatty-acid-CoA ligase 0.042 0.0273 0.0547
Mycobacterium tuberculosis Conserved hypothetical protein 0.0092 0.004 0.0069
Echinococcus multilocularis aldo keto reductase 0.0062 0.002 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0009 0.0057
Schistosoma mansoni topbp1 0.0057 0.0016 0.0061
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0126 0.0065 0.1573
Trichomonas vaginalis Clan MH, family M18, aspartyl aminopeptidase-like metallopeptidase 0.0072 0.0027 0.0189
Echinococcus granulosus survival motor neuron protein 1 0.2423 0.1694 0.6623
Echinococcus multilocularis hexokinase 0.0077 0.003 0.0029
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0098 0.0045 0.0868
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0062 0.002 0.0075
Schistosoma mansoni nuclear receptor nhr-48 0.0063 0.002 0.0077
Entamoeba histolytica deoxycytidyl transferase, putative 0.0092 0.004 0.0558
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0009 0.0057
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0059 0.0017 0.0031

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) > 1000 nM Inhibition of PARP1 in human C41 cells ChEMBL. 20045315
IC50 (binding) = 12.45658 um PUBCHEM_BIOASSAY: Estrogen Receptor-beta Coactivator Binding Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 633 (Primary screen preceding this dose response confirmation assay.)] ChEMBL. No reference
Ki (binding) = 172 nM Inhibition of PARP1 by microplate scintillation counting ChEMBL. 20045315
Potency (functional) 1 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 7.3078 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 9.2 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493106, AID493143] ChEMBL. No reference
Potency (functional) 9.285 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 17.7828 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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