Detailed information for compound 113760

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 369.411 | Formula: C21H23NO5
  • H donors: 2 H acceptors: 5 LogP: 2.08 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(NCC(=O)O)CCC(C1=C(C)C(=O)C(=C(C1=O)C)C)c1ccccc1
  • InChi: 1S/C21H23NO5/c1-12-13(2)21(27)19(14(3)20(12)26)16(15-7-5-4-6-8-15)9-10-17(23)22-11-18(24)25/h4-8,16H,9-11H2,1-3H3,(H,22,23)(H,24,25)
  • InChiKey: MJMNSQJLMXSWGU-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) 0.0044 0.0252 0.1642
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 0.1311
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0186 0.0188
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0186 0.0625
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0144 0.1002 0.748
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.1328 0.9886 1
Onchocerca volvulus 0.0017 0.0053 0.0398
Brugia malayi Ras-related protein Rac1 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0041 0.0234 0.0234
Echinococcus granulosus cathepsin l cysteine peptidase 0.0015 0.0038 0.0038
Brugia malayi Calcitonin receptor-like protein seb-1 0.0045 0.0262 0.0262
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0031 0.0031
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0069 0.0069
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0019 0.0069 0.0069
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Loa Loa (eye worm) hypothetical protein 0.0081 0.0529 0.0529
Trypanosoma cruzi cruzipain precursor, putative 0.0058 0.0357 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0186 0.0172
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Entamoeba histolytica eukaryotic initiation factor 4E, putative 0.0158 0.1112 0.1124
Brugia malayi Phosphoribosyl transferase domain containing protein 0.0187 0.1326 0.1326
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0038 0.0038
Onchocerca volvulus 0.0015 0.0038 0.0283
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0147 0.103 0.1027
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0058 0.0361 0.0365
Mycobacterium tuberculosis Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor 0.0143 0.0998 0.6021
Schistosoma mansoni cell polarity protein 0.014 0.0976 0.0987
Trypanosoma brucei hypothetical protein, conserved 0.0058 0.0361 0.033
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Loa Loa (eye worm) hypothetical protein 0.0058 0.0361 0.0361
Echinococcus multilocularis ras gtpase 0.014 0.0976 0.0986
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0186 0.0188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0361 0.2506
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.002
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0058 0.0361 0.0364
Trichomonas vaginalis rho5 protein, putative 0.0012 0.0016 0.0017
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0069 0.0069
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Echinococcus granulosus cathepsin l1 0.0015 0.0038 0.0038
Toxoplasma gondii hypothetical protein 0.0158 0.1112 0.1091
Leishmania major hypothetical protein, conserved 0.0158 0.1112 0.1093
Leishmania major cathepsin L-like protease 0.0058 0.0357 0.0326
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0058 0.0361 0.0365
Giardia lamblia Adenine phosphoribosyltransferase 0.0044 0.0252 0.1801
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0038 0.0038
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.0752 0.4386
Plasmodium vivax hypothetical protein, conserved 0.0158 0.1112 0.8334
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus multilocularis ras C3 botulinum toxin substrate 2 0.0012 0.0016 0.0016
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0361 0.033
Echinococcus granulosus survival motor neuron protein 1 0.0238 0.1708 0.1727
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0186 0.0172
Leishmania major eukaryotic translation initiation factor-like 0.1328 0.9886 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0567 0.0573
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0357 0.0345
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0361 0.0365
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0022 0.0092 0.0093
Leishmania major eukaryotic translation initiation factor-like protein 0.1328 0.9886 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Schistosoma mansoni cathepsin F (C01 family) 0.0015 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0035 0.0186 0.0188
Trichomonas vaginalis Ribose-phosphate pyrophosphokinase, putative 0.0044 0.0252 0.0255
Mycobacterium tuberculosis Conserved protein 0.0035 0.0186 0.0625
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1327
Brugia malayi Bromodomain containing protein 0.0037 0.0203 0.0203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0048 0.0049
Onchocerca volvulus Putative GMP reductase 0.0063 0.04 0.3016
Echinococcus granulosus cathepsin L cysteine proteinase 0.0015 0.0038 0.0038
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0186 0.0186
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0069 0.0034
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0186 0.0625
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0529 0.0529
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0069 0.0069
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Treponema pallidum phosphoribosylpyrophosphate synthetase 0.0044 0.0252 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0094 0.002
Onchocerca volvulus Cathepsin F homolog 0.0015 0.0038 0.0283
Mycobacterium tuberculosis Probable pyrimidine operon regulatory protein PyrR 0.0044 0.0252 0.1067
Brugia malayi N-terminal motif family protein 0.0175 0.1237 0.1237
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0144 0.1002 0.748
Trichomonas vaginalis eukaryotic translation initiation factor 4E type, putative 0.0158 0.1112 0.1124
Loa Loa (eye worm) hypothetical protein 0.0017 0.0048 0.0048
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0529 0.0535
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0185 0.0187
Leishmania major cathepsin L-like protease 0.0058 0.0357 0.0326
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0382 0.0386
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Onchocerca volvulus 0.0015 0.0038 0.0283
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0567 0.0573
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0094 0.0016
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 0.1311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Leishmania major adenine phosphoribosyltransferase 0.0044 0.0252 0.022
Plasmodium falciparum eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.8334
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0529 0.0535
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0017 0.0053 0.0119
Schistosoma mansoni hypothetical protein 0.0031 0.0155 0.0157
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0153 0.107 0.1067
Loa Loa (eye worm) beta-lactamase 0.0035 0.0186 0.0186
Echinococcus multilocularis neuropeptide receptor A26 0.042 0.3078 0.3113
Entamoeba histolytica hypothetical protein 0.0019 0.0069 0.0069
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0069 0.0241
Toxoplasma gondii IMP dehydrogenas 0.0153 0.107 0.1048
Loa Loa (eye worm) hypothetical protein 0.0028 0.0133 0.0133
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.015
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0187 0.1326 0.1341
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Entamoeba histolytica hypothetical protein 0.0023 0.0094 0.0095
Trypanosoma brucei Eukaryotic translation initiation factor 4E-3 0.0158 0.1112 0.1093
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0058 0.0361 0.0349
Schistosoma mansoni cell polarity protein 0.014 0.0976 0.0987
Toxoplasma gondii orotate phosphoribosyltransferase 0.0044 0.0252 0.0218
Brugia malayi latrophilin 2 splice variant baaae 0.0031 0.0155 0.0155
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0019 0.0069 0.0069
Leishmania major inosine-5-monophosphate dehydrogenase 0.0153 0.107 0.105
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0153 0.107 0.107
Echinococcus granulosus expressed protein 0.0375 0.274 0.2771
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Entamoeba histolytica hypothetical protein 0.0158 0.1112 0.1124
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0095 0.0058
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.033
Leishmania major guanosine monophosphate reductase 0.0153 0.107 0.105
Brugia malayi GTP-binding protein 0.014 0.0976 0.0976
Plasmodium vivax translation initiation factor 4E, putative 0.0158 0.1112 0.8334
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0185 0.0187
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0186 0.0188
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0567 0.0573
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0153 0.107 1
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.028 0.2028 0.2038
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0058 0.0361 0.0365
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0069 0.0069
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Schistosoma mansoni gtpase_rho 0.0012 0.0016 0.0017
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Echinococcus multilocularis adenine phosphoribosyltransferase 0.0044 0.0252 0.0255
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0073 0.0468 0.3849
Echinococcus granulosus zinc finger protein 0.0019 0.0066 0.0067
Mycobacterium ulcerans amidophosphoribosyltransferase 0.0044 0.0252 0.1301
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0086 0.0567 0.0573
Onchocerca volvulus 0.0015 0.0038 0.0283
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0095 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Brugia malayi PHD-finger family protein 0.0024 0.0105 0.0105
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0088 0.0088
Trichomonas vaginalis hypothetical protein 0.0158 0.1112 0.1124
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0186 0.0625
Giardia lamblia hypothetical protein 0.0158 0.1112 0.8361
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0069 0.0069
Echinococcus multilocularis regulator of G protein signaling 7 0.0028 0.0133 0.0134
Plasmodium falciparum hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 1
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0081 0.0528 0.0534
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis eukaryotic translation initiation factor 4E type, putative 0.0158 0.1112 0.1124
Schistosoma mansoni hypothetical protein 0.002 0.0074 0.0075
Entamoeba histolytica hypothetical protein 0.0035 0.0186 0.0188
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0053 0.0037
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0147 0.103 0.1041
Brugia malayi regulator of G-protein signaling rgs-7 0.0019 0.0069 0.0069
Loa Loa (eye worm) translation initiation factor 4E 0.1328 0.9886 0.9886
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0186 0.0188
Mycobacterium tuberculosis Conserved protein 0.0035 0.0186 0.0625
Leishmania major hypothetical protein, conserved 0.0035 0.0186 0.0153
Mycobacterium ulcerans hypoxanthine-guanine phosphoribosyltransferase Hpt 0.0187 0.1326 1
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0069 0.0069
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0095 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0015 0.0035 0.0036
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0053 0.0053
Leishmania major orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative 0.0044 0.0252 0.022
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0094 0.0439
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0022 0.0092 0.0093
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0186 0.0188
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0382 0.035
Schistosoma mansoni sensor histidine kinase/response regulator 0.0022 0.0092 0.0093
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.1328 0.9886 1
Plasmodium falciparum phosphodiesterase gamma, putative 0.0058 0.0361 0.2506
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0094 0.0439
Mycobacterium leprae Probable lipase LipE 0.0035 0.0186 0.0962
Mycobacterium ulcerans bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase 0.0044 0.0252 0.1301
Schistosoma mansoni uracil phosphoribosyltransferase 0.0044 0.0252 0.0255
Trypanosoma cruzi Eukaryotic translation initiation factor 4E type 5, putative 0.0158 0.1112 0.111
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0019 0.0069 0.0069
Brugia malayi PXA domain containing protein 0.0019 0.0069 0.0069
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0069 0.0069
Brugia malayi GMP reductase 0.0063 0.04 0.04
Giardia lamblia Hypothetical protein 0.0158 0.1112 0.8361
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0186 0.0188
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.2506
Echinococcus multilocularis expressed protein 0.0375 0.274 0.2771
Onchocerca volvulus 0.0012 0.0016 0.0124
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0063 0.04 0.04
Plasmodium falciparum cysteine repeat modular protein 1 0.0017 0.0053 0.0119
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0382 0.2351
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.1112 0.1124
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0361 0.0364
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0147 0.103 0.103
Schistosoma mansoni DNA helicase recq5 0.0019 0.0069 0.0069
Mycobacterium leprae AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) 0.0044 0.0252 0.1642
Onchocerca volvulus 0.0015 0.0038 0.0283
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0058 0.0361 0.033
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0186 0.0153
Mycobacterium tuberculosis Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) 0.0044 0.0252 0.1067
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0382 0.0386
Echinococcus granulosus GPCR family 2 0.0014 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.0015 0.0038 0.0002
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0045 0.0262 0.0262
Schistosoma mansoni z-protein (S1r protein) 0.0028 0.0133 0.0135
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0361 0.0364
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0529 0.0534
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0069 0.0069
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0153 0.107 0.1082
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0038 0.0037
Echinococcus multilocularis tissue type plasminogen activator 0.0017 0.0053 0.0053
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0058 0.0361 0.0365
Echinococcus multilocularis regulator of G protein signaling 0.0019 0.0069 0.0069
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Schistosoma mansoni survival motor neuron protein 0.0048 0.0288 0.0291
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0069 0.0069
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0361 0.0349
Brugia malayi hypothetical protein 0.0019 0.0069 0.0069
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0015 0.0038 0.0037
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Mycobacterium tuberculosis Conserved protein 0.0035 0.0186 0.0625
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0069 0.0069
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1327
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Giardia lamblia hypothetical protein 0.0058 0.0361 0.2627
Schistosoma mansoni DNA helicase recq1 0.0019 0.0069 0.0069
Trichomonas vaginalis eukaryotic translation initiation factor 4E type, putative 0.0158 0.1112 0.1124
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0147 0.103 0.101
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.028 0.2028 0.2023
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma cruzi ISWI complex protein 0.0015 0.0035 0.0019
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0357 0.0345
Loa Loa (eye worm) hypothetical protein 0.0175 0.1237 0.1237
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0019 0.0069 0.0069
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0044 0.0252 0.0255
Loa Loa (eye worm) hypothetical protein 0.0031 0.0155 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0048 0.0049
Echinococcus multilocularis regulator of G protein signaling 3 0.0019 0.0069 0.0069
Onchocerca volvulus Adenine phosphoribosyltransferase homolog 0.0044 0.0252 0.1902
Loa Loa (eye worm) PDE1B protein 0.0147 0.103 0.103
Leishmania major hypothetical protein, conserved 0.0017 0.0053 0.0018
Brugia malayi Kringle domain containing protein 0.0017 0.0053 0.0053
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.0031
Brugia malayi Adenine phosphoribosyltransferase 0.0044 0.0252 0.0252
Echinococcus multilocularis geminin 0.0317 0.2306 0.2332
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.1112 0.1124
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0058 0.0361 0.0361
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0069 0.0069
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0361 0.0349
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Plasmodium vivax hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Toxoplasma gondii kringle domain-containing protein 0.0017 0.0053 0.0016
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0094 0.0057
Brugia malayi Papain family cysteine protease containing protein 0.0015 0.0038 0.0038
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0048 0.0049
Echinococcus granulosus neuropeptide receptor A26 0.042 0.3078 0.3113
Loa Loa (eye worm) RGS-3 protein 0.0019 0.0069 0.0069
Plasmodium falciparum phosphodiesterase delta, putative 0.0058 0.0361 0.2506
Toxoplasma gondii ABC1 family protein 0.0035 0.0186 0.0151
Schistosoma mansoni rac gtpase 0.0012 0.0016 0.0017
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0147 0.103 0.1008
Brugia malayi beta-lactamase family protein 0.0035 0.0186 0.0186
Echinococcus multilocularis hypoxanthine guanine phosphoribosyltransferase 0.0187 0.1326 0.1341
Mycobacterium ulcerans orotate phosphoribosyltransferase 0.0044 0.0252 0.1301
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0069 0.0241
Giardia lamblia Guanine phosphoribosyltransferase 0.0187 0.1326 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Echinococcus multilocularis beta adrenergic receptor kinase 0.0019 0.0069 0.0069
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0382 0.2351
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1327
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0382 0.2351
Schistosoma mansoni bromodomain containing protein 0.0061 0.0384 0.0389
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0048 0.0048
Trichomonas vaginalis sensor histidine kinase, putative 0.0022 0.0092 0.0093
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.2506
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0147 0.103 0.1042
Loa Loa (eye worm) fibroinase 0.0015 0.0038 0.0038
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.008 0.0525 0.4436
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0361 0.0365
Trichomonas vaginalis eukaryotic translation initiation factor 4E type, putative 0.0158 0.1112 0.1124
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0095 0.0445
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0147 0.103 0.1008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Mycobacterium tuberculosis Conserved hypothetical protein 0.011 0.0752 0.4386
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0095 0.0061
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0028 0.0133 0.0133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.022
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0069 0.0069
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0031 0.0031
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0153 0.107 0.1067
Leishmania major cathepsin L-like protease 0.0015 0.0038 0.0002
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0094 0.0025
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0045 0.0262 0.0262
Trypanosoma brucei Eukaryotic translation initiation factor 4E type 5 0.0158 0.1112 0.1093
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-4 0.0158 0.1112 0.111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Brugia malayi A-kinase anchor protein 10, precursor 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0038 0.0038
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0361 0.0349
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0069 0.0069
Trypanosoma cruzi major cysteine proteinase, putative 0.0045 0.0264 0.0251
Leishmania major hypothetical protein, conserved 0.0023 0.0095 0.0061
Loa Loa (eye worm) GMP reductase 0.0063 0.04 0.04
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0094 0.006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Onchocerca volvulus 0.0035 0.0186 0.1401
Brugia malayi translation initiation factor 4E 0.1328 0.9886 0.9886
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0069 0.0069
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0069 0.0069
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.033
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Echinococcus granulosus neuropeptide s receptor 0.042 0.3078 0.3113
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0147 0.103 0.101
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0058 0.0361 0.0364
Leishmania major cathepsin L-like protease 0.0015 0.0038 0.0002
Schistosoma mansoni Adenine phosphoribosyltransferase 0.0044 0.0252 0.0255
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0186 0.0625
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0382 0.0386
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0147 0.103 0.1027
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0187 0.1326 0.1342
Entamoeba histolytica cysteine proteinase, putative 0.0015 0.0038 0.0038
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0153 0.107 0.1081
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0015 0.0038 0.0038
Leishmania major eukaryotic translation initiation factor 4e, putative 0.0158 0.1112 0.1093
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Wolbachia endosymbiont of Brugia malayi amidophosphoribosyltransferase 0.0044 0.0252 0.1642
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus tissue type plasminogen activator 0.0017 0.0053 0.0053
Brugia malayi beta-lactamase 0.0035 0.0186 0.0186
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0382 0.1929
Treponema pallidum adenine phosphoribosyltransferase 0.0044 0.0252 1
Plasmodium vivax orotate phosphoribosyltransferase, putative 0.0044 0.0252 0.1666
Leishmania major hypothetical protein, conserved 0.0058 0.0361 0.033
Echinococcus multilocularis bloom syndrome protein 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus geminin 0.0317 0.2306 0.2332
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0069 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0186 0.0625
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Loa Loa (eye worm) RecQ helicase 0.0019 0.0069 0.0069
Loa Loa (eye worm) hypothetical protein 0.0069 0.0438 0.0438
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Brugia malayi hypothetical protein 0.0035 0.0186 0.0186
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0069 0.0399
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0069 0.0069
Echinococcus multilocularis neuropeptide s receptor 0.042 0.3078 0.3113
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.001 0.0001 0.0001
Schistosoma mansoni regulator of G protein signaling 0.0028 0.0133 0.0135
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0069 0.0069
Trypanosoma brucei Eukaryotic translation initiation factor 4E-4 0.0158 0.1112 0.1093
Echinococcus multilocularis cysteine protease 0.0015 0.0038 0.0037
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Leishmania major eukaryotic translation initiation factor, putative 0.0158 0.1112 0.1093
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0015 0.0038 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0186 0.1151
Loa Loa (eye worm) IMP dehydrogenase 1 0.0153 0.107 0.107
Schistosoma mansoni hypothetical protein 0.0035 0.0186 0.0188
Brugia malayi Bromodomain containing protein 0.0073 0.0469 0.0469
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0086 0.0567 0.0567
Onchocerca volvulus 0.0015 0.0038 0.0283
Leishmania major hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 0.1311
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Echinococcus granulosus uridine 5' monophosphate synthase 0.0044 0.0252 0.0255
Treponema pallidum hypothetical protein 0.0044 0.0252 1
Schistosoma mansoni zinc finger protein 0.0019 0.0066 0.0067
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0031 0.0031
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus multilocularis Regulator of G protein signaling 20 0.0019 0.0069 0.0069
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Leishmania major xanthine phosphoribosyltransferase 0.0187 0.1326 0.1311
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0031 0.0031
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0186 0.0625
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0095 0.0445
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Trichomonas vaginalis rho4, putative 0.0012 0.0016 0.0017
Mycobacterium leprae conserved hypothetical protein 0.0035 0.0186 0.0962
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Loa Loa (eye worm) eukaryotic translation initiation factor 4E-1 0.0158 0.1112 0.1112
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0044 0.0252 0.0255
Mycobacterium leprae Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho 0.0143 0.0998 0.9268
Loa Loa (eye worm) hypothetical protein 0.1343 1 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0186 0.0188
Onchocerca volvulus 0.0081 0.0529 0.3988
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0186 0.0762
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0094 0.006
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.1328 0.9886 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0058 0.0361 0.2506
Trichomonas vaginalis rho4, putative 0.0012 0.0016 0.0017
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0088 0.0089
Entamoeba histolytica cysteine protease, putative 0.0015 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0317 0.2306 0.2332
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0048 0.0048
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0186 0.0188
Loa Loa (eye worm) hypothetical protein 0.0238 0.1708 0.1708
Onchocerca volvulus 0.0035 0.0186 0.1401
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Entamoeba histolytica eukaryotic initiation factor 4E, putative 0.0158 0.1112 0.1124
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Echinococcus granulosus ras gtpase 0.014 0.0976 0.0987
Brugia malayi hypothetical protein 0.0015 0.0034 0.0034
Brugia malayi eukaryotic translation initiation factor 4E-1 0.0158 0.1112 0.1112
Schistosoma mansoni orotidine 5'-phosphate decarboxylase 0.0044 0.0252 0.0255
Schistosoma mansoni hypothetical protein 0.0317 0.2306 0.2332
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0058 0.0361 0.0364
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0069 0.0053
Echinococcus multilocularis survival motor neuron protein 1 0.0238 0.1708 0.1727
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0035 0.0186 0.0188
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.0058 0.0361 0.2627
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0361 0.0365
Mycobacterium ulcerans lipase LipD 0.0035 0.0186 0.0762
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0019 0.0069 0.0069
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0567 0.0573
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0153 0.107 0.105
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0019 0.0069 0.0069
Trichomonas vaginalis hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1342
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0186 0.0187
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Mycobacterium tuberculosis Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) 0.0044 0.0252 0.1067
Brugia malayi Eukaryotic translation initiation factor 4E type 3, putative 0.0158 0.1112 0.1112
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0058 0.0358 0.0362
Schistosoma mansoni axis inhibition protein axin 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0158 0.1112 0.1091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Plasmodium falciparum eukaryotic translation initiation factor 4E 0.0158 0.1112 0.8334
Trypanosoma brucei orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0044 0.0252 0.022
Loa Loa (eye worm) GTP-binding protein 0.014 0.0976 0.0976
Trichomonas vaginalis ribose-phosphate pyrophosphokinase, putative 0.0044 0.0252 0.0255
Loa Loa (eye worm) hypothetical protein 0.0045 0.0262 0.0262
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0147 0.103 0.1042
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0019 0.0069 0.0034
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0038 0.0283
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0153 0.107 0.792
Brugia malayi regulator of G-protein signaling egl-10 0.0028 0.0133 0.0133
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0186 0.0762
Trypanosoma cruzi Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Onchocerca volvulus Cathepsin L homolog 0.0015 0.0038 0.0283
Brugia malayi beta-lactamase family protein 0.0035 0.0186 0.0186
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.2506
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0186 0.0186
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0022 0.0092 0.0093
Echinococcus granulosus Regulator of G protein signaling 20 0.0019 0.0069 0.0069
Leishmania major cAMP-specific phosphodiesterase, putative 0.028 0.2028 0.2023
Mycobacterium tuberculosis Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) 0.0044 0.0252 0.1067
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0153 0.107 1
Echinococcus multilocularis axis inhibition protein axin 0.0019 0.0069 0.0069
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0086 0.0567 0.0573
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0186 0.0188
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.1328 0.9886 1
Brugia malayi hypothetical protein 0.0146 0.1023 0.1023
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0058 0.0361 0.0361
Echinococcus multilocularis Ras C3 botulinum toxin substrate 1 0.0012 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0088 0.0089
Trichomonas vaginalis receptor histidine kinase, putative 0.0022 0.0092 0.0093
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0022 0.0092 0.0093
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0063 0.04 0.04
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0086 0.0567 0.0573
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0048 0.0049
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0069 0.0069
Trichomonas vaginalis esterase, putative 0.0035 0.0186 0.0188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0095 0.0095
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0001
Onchocerca volvulus 0.0187 0.1326 1
Onchocerca volvulus 0.0146 0.1023 0.7713
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Echinococcus granulosus regulator of G protein signaling 7 0.0028 0.0133 0.0135
Trichomonas vaginalis eukaryotic translation initiation factor 4E type, putative 0.0158 0.1112 0.1124
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0144 0.1002 0.7369
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0186 0.0188
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0153 0.107 0.6496
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0153 0.107 0.1067
Loa Loa (eye worm) cysteine protease 0.0015 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0058 0.0361 0.0361
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0058 0.0361 0.0365
Trypanosoma cruzi hypothetical protein, conserved 0.0058 0.0361 0.0349
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0094 0.0025
Mycobacterium leprae conserved hypothetical protein 0.011 0.0752 0.6751
Brugia malayi small GTPase 0.0012 0.0016 0.0016
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0073 0.0468 0.3048
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0094 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0361 0.0365
Brugia malayi PXA domain containing protein 0.0019 0.0069 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0361 0.0365
Giardia lamblia Hypothetical protein 0.0058 0.0361 0.2627
Loa Loa (eye worm) orotate phosphoribosyltransferase 0.0044 0.0252 0.0252
Mycobacterium tuberculosis Conserved protein 0.0044 0.0252 0.1067
Trypanosoma cruzi eukaryotic translation initiation factor 4E (eIF4E) interacting protein, putative 0.0158 0.1112 0.111
Trypanosoma brucei Eukaryotic translation initiation factor 4E-2 0.0158 0.1112 0.1093
Leishmania major cathepsin L-like protease 0.0015 0.0038 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0015 0.0038 0.0021
Onchocerca volvulus 0.0048 0.0288 0.217
Onchocerca volvulus Putative eukaryotic translation initiation factor 4e 0.0158 0.1112 0.8382
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma brucei Adenine phosphoribosyltransferase, putative 0.0044 0.0252 0.022
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.1328 0.9886 1
Loa Loa (eye worm) hypothetical protein 0.1285 0.9563 0.9563
Brugia malayi Protein kinase domain containing protein 0.0017 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0037 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0017 0.0053 0.0053
Brugia malayi hypothetical protein 0.0238 0.1708 0.1708
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0361 0.0361
Loa Loa (eye worm) hypothetical protein 0.0039 0.022 0.022
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) ctsf protein 0.0015 0.0038 0.0038
Echinococcus multilocularis zinc finger protein 0.0019 0.0066 0.0066
Trypanosoma cruzi GMP reductase 0.0153 0.107 0.1067
Giardia lamblia Translation elongation factor 0.0158 0.1112 0.8361
Loa Loa (eye worm) hypothetical protein 0.0146 0.1023 0.1023
Mycobacterium ulcerans adenine phosphoribosyltransferase 0.0044 0.0252 0.1301
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0153 0.107 0.1082
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0069 0.0069
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.1328 0.9886 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0019 0.0069 0.0069
Brugia malayi hypothetical protein 0.0019 0.0069 0.0069
Plasmodium vivax phosphodiesterase gamma, putative 0.0058 0.0361 0.2506
Loa Loa (eye worm) hypothetical protein 0.0058 0.0361 0.0361
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0019 0.0069 0.0069
Trichomonas vaginalis sensor histidine kinase, putative 0.0022 0.0092 0.0093
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0052 0.0052
Echinococcus granulosus eukaryotic translation initiation factor 4E type 0.0158 0.1112 0.1124
Loa Loa (eye worm) eukaryotic translation initiation factor 4E type 3 0.0158 0.1112 0.1112
Echinococcus granulosus beta-adrenergic receptor kinase 0.0019 0.0069 0.0069
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 0.1342
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0175 0.1237 0.9326
Echinococcus granulosus adenine phosphoribosyltransferase 0.0044 0.0252 0.0255
Echinococcus multilocularis uridine 5' monophosphate synthase 0.0044 0.0252 0.0255
Echinococcus multilocularis GPCR, family 2 0.0014 0.0031 0.0031
Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT 0.0187 0.1326 0.1309
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0038 0.0037
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.1328 0.9886 1
Plasmodium falciparum orotate phosphoribosyltransferase 0.0044 0.0252 0.1666
Loa Loa (eye worm) adenine phosphoribosyltransferase 0.0044 0.0252 0.0252
Loa Loa (eye worm) hypothetical protein 0.0035 0.0186 0.0186
Echinococcus granulosus regulator of G protein signaling 7 0.0028 0.0133 0.0135
Giardia lamblia Hypothetical protein 0.0158 0.1112 0.8361
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0031 0.0031
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-3 0.0158 0.1112 0.111
Entamoeba histolytica translation initiation factor 4e, putative 0.0158 0.1112 0.1124
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0058 0.0361 0.0349
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0058 0.0358 0.0362
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Entamoeba histolytica Rho family GTPase 0.0012 0.0016 0.0017
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0044 0.0252 0.0255
Mycobacterium leprae conserved hypothetical protein 0.011 0.0752 0.6751
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0017 0.0053 0.0053
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0058 0.0361 0.0361
Entamoeba histolytica hypothetical protein 0.0158 0.1112 0.1124
Onchocerca volvulus 0.0015 0.0038 0.0283
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0058 0.0361 0.0365
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0382 0.0386
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferase 0.0187 0.1326 0.1342
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0015 0.0038 0.0038
Loa Loa (eye worm) PXA domain-containing protein 0.0019 0.0069 0.0069
Leishmania major cysteine peptidase A (CPA) 0.0015 0.0038 0.0002
Echinococcus multilocularis regulator of G protein signaling 7 0.0028 0.0133 0.0134
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Echinococcus granulosus hypoxanthine guanine phosphoribosyltransferase 0.0187 0.1326 0.1342
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0069 0.0069
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.2506
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0147 0.103 0.1041
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0058 0.0361 0.0364
Brugia malayi orotate phosphoribosyltransferase family protein 0.0044 0.0252 0.0252
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0019 0.0069 0.0069
Brugia malayi Bloom's syndrome protein homolog 0.0019 0.0069 0.0069
Entamoeba histolytica hypothetical protein 0.0019 0.0069 0.0069
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0382 0.0352
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0031 0.0031
Mycobacterium ulcerans hypothetical protein 0.0035 0.0186 0.0762
Echinococcus granulosus regulator of G protein signaling 3 0.0019 0.0069 0.0069
Echinococcus multilocularis cysteine protease 0.0015 0.0038 0.0037
Brugia malayi hypothetical protein 0.0023 0.0095 0.0095
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0147 0.103 0.77
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0058 0.0361 0.0365
Brugia malayi Cathepsin L-like precursor 0.0015 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0058 0.0357 0.0326
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Entamoeba histolytica hypothetical protein 0.0019 0.0069 0.0069
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0031 0.0031
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0048 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.1112 0.1124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0069 0.0069
Trypanosoma cruzi GMP reductase 0.0153 0.107 0.1067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Echinococcus granulosus ras C3 botulinum toxin substrate 2 0.0012 0.0016 0.0017
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0147 0.103 0.1042
Trypanosoma brucei hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1311
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-4 0.0158 0.1112 0.111
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0058 0.0361 0.0365
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0223 0.1597 1
Trypanosoma cruzi Eukaryotic translation initiation factor 4E type 5, putative 0.0158 0.1112 0.111
Echinococcus multilocularis cathepsin L cysteine protease 0.0015 0.0038 0.0037
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0058 0.0361 0.0365
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0186 0.0187
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0048 0.0049
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0094 0.0057
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0058 0.0361 0.0361
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0074 0.0074
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0058 0.0361 0.0365
Entamoeba histolytica hypothetical protein 0.0035 0.0186 0.0188
Leishmania major cathepsin L-like protease 0.0015 0.0038 0.0002
Trypanosoma cruzi hypoxanthine-guanine phosphoribosyltransferase, putative 0.0187 0.1326 0.1327
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Trypanosoma brucei GMP reductase 0.0153 0.107 0.105
Trypanosoma cruzi cysteine peptidase, putative 0.0058 0.0357 0.0345
Echinococcus granulosus bloom syndrome protein 0.0019 0.0069 0.0069
Loa Loa (eye worm) small GTPase 0.0012 0.0016 0.0016
Leishmania major hypothetical protein, conserved 0.0058 0.0361 0.033
Brugia malayi GTP-binding protein, identical 0.014 0.0976 0.0976
Mycobacterium tuberculosis Conserved protein 0.0044 0.0252 0.1067
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0095 0.0445
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.1328 0.9886 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0086 0.0567 0.0567
Echinococcus granulosus axis inhibition protein axin 0.0019 0.0069 0.0069
Mycobacterium ulcerans beta-lactamase 0.0035 0.0186 0.0762
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0069 0.0069
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.008 0.0525 0.2882
Trypanosoma cruzi ISWI complex protein 0.0015 0.0035 0.0019
Wolbachia endosymbiont of Brugia malayi orotate phosphoribosyltransferase 0.0044 0.0252 0.1642
Trichomonas vaginalis GTPase_rho, putative 0.0012 0.0016 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Trypanosoma cruzi orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative 0.0044 0.0252 0.0239
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0053 0.0319 0.0307
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.0031
Trichomonas vaginalis DNA helicase recq, putative 0.0019 0.0069 0.0069
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0015 0.0038 0.0038
Brugia malayi Regulator of G protein signaling domain containing protein 0.0019 0.0069 0.0069
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0058 0.0361 0.0328
Schistosoma mansoni regulator of G protein signaling 0.0019 0.0069 0.0069
Trypanosoma cruzi eukaryotic translation initiation factor 4E (eIF4E) interacting protein, putative 0.0158 0.1112 0.111
Loa Loa (eye worm) rac GTPase 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0015 0.0038 0.0038
Onchocerca volvulus 0.0035 0.0186 0.1401
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0186 0.0625
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.0252 0.1067
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.1328 0.9886 1
Schistosoma mansoni hypothetical protein 0.0048 0.0288 0.0291
Onchocerca volvulus 0.0015 0.0038 0.0283
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0058 0.0361 0.0365
Leishmania major cathepsin L-like protease 0.0058 0.0357 0.0326
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0158 0.1112 0.1124
Schistosoma mansoni zinc finger protein 0.0015 0.0035 0.0036
Leishmania major hypothetical protein, conserved 0.0158 0.1112 0.1093
Trichomonas vaginalis receptor histidine kinase, putative 0.0022 0.0092 0.0093
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0069 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0015 0.0038 0.0038
Mycobacterium ulcerans hypothetical protein 0.0044 0.0252 0.1301

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 0 % In vitro percent inhibition against U-44,069 (10e-7 M) induced contraction of rabbit aorta at 10e-5 M concentration. ChEMBL. 2769691

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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