Detailed information for compound 1384188

Basic information

Technical information
  • TDR Targets ID: 1384188
  • Name: N'-[[2,4,6-trioxo-1-(4-propan-2-ylphenyl)-1,3 -diazinan-5-ylidene]methyl]pyridine-4-carbohy drazide
  • MW: 393.396 | Formula: C20H19N5O4
  • H donors: 3 H acceptors: 5 LogP: 2.62 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(c1ccc(cc1)N1C(=O)NC(=O)/C(=C\NNC(=O)c2ccncc2)/C1=O)C
  • InChi: 1S/C20H19N5O4/c1-12(2)13-3-5-15(6-4-13)25-19(28)16(18(27)23-20(25)29)11-22-24-17(26)14-7-9-21-10-8-14/h3-12,22H,1-2H3,(H,24,26)(H,23,27,29)/b16-11+
  • InChiKey: OSDPNILRUDVVOR-LFIBNONCSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N'-[(E)-[2,4,6-trioxo-1-(4-propan-2-ylphenyl)-1,3-diazinan-5-ylidene]methyl]pyridine-4-carbohydrazide
  • N'-[[1-(4-isopropylphenyl)-2,4,6-trioxo-hexahydropyrimidin-5-ylidene]methyl]pyridine-4-carbohydrazide
  • N'-[(E)-[1-(4-isopropylphenyl)-2,4,6-trioxo-hexahydropyrimidin-5-ylidene]methyl]pyridine-4-carbohydrazide
  • N'-[(E)-[1-(4-isopropylphenyl)-2,4,6-trioxo-5-hexahydropyrimidinylidene]methyl]-4-pyridinecarbohydrazide
  • N'-[[1-(4-isopropylphenyl)-2,4,6-trioxo-5-hexahydropyrimidinylidene]methyl]-4-pyridinecarbohydrazide
  • N'-[(E)-[1-(4-isopropylphenyl)-2,4,6-triketo-hexahydropyrimidin-5-ylidene]methyl]isonicotinohydrazide
  • N'-[[1-(4-isopropylphenyl)-2,4,6-triketo-hexahydropyrimidin-5-ylidene]methyl]isonicotinohydrazide
  • SMR000217856
  • ZINC04812121
  • STOCK2S-47203
  • Isonicotinic acid N'-[1-(4-isopropyl-phenyl)-2,4,6-trioxo-tetrahydro-pyrimidin-(5E)-ylidenemethyl]-hydrazide
  • MLS000591059

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens multiple endocrine neoplasia I No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific demethylase 4E Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), beta Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania braziliensis mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Mycobacterium tuberculosis Conserved hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Trypanosoma congolense mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma brucei mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Leishmania infantum mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania major mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium ulcerans hypothetical protein Get druggable targets OG5_130965 All targets in OG5_130965
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Leishmania donovani mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative Get druggable targets OG5_130965 All targets in OG5_130965
Leishmania mexicana mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Trypanosoma brucei gambiense mitochondrial DNA polymerase beta Get druggable targets OG5_130965 All targets in OG5_130965
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative polymerase (DNA directed), beta 335 aa 303 aa 32.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0298 0.0326
Schistosoma mansoni cpg binding protein 0.0035 0.0276 0.03
Echinococcus granulosus muscleblind protein 0.018 0.1776 0.207
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0671 0.0766
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0062 0.0563 0.126
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0173 0.1696 0.4444
Loa Loa (eye worm) hypothetical protein 0.018 0.1776 0.3203
Toxoplasma gondii hypothetical protein 0.0059 0.0525 0.0769
Brugia malayi dUTP diphosphatase 0.0538 0.5453 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0298 0.0326
Schistosoma mansoni cpg binding protein 0.0037 0.0296 0.0324
Schistosoma mansoni cpg binding protein 0.0037 0.0296 0.0324
Echinococcus granulosus microtubule associated protein 2 0.0833 0.8498 1
Brugia malayi Pre-SET motif family protein 0.0252 0.2514 0.4569
Echinococcus multilocularis cpg binding protein 0.0037 0.0296 0.0276
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.3674 1
Brugia malayi jmjC domain containing protein 0.0019 0.0114 0.0134
Brugia malayi jmjC domain containing protein 0.0019 0.0114 0.0134
Echinococcus multilocularis dUTP pyrophosphatase 0.0538 0.5453 0.5444
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0071 0.065 0.0742
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0134 0.0113
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0671 0.0766
Brugia malayi jmjC domain containing protein 0.0071 0.065 0.1124
Toxoplasma gondii deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0538 0.5453 1
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0114 0.0109
Brugia malayi jmjC domain containing protein 0.0019 0.0114 0.0134
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0447 0.0935
Brugia malayi Pre-SET motif family protein 0.0037 0.0298 0.0473
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0043 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0114 0.0131
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0114 0.0109
Entamoeba histolytica hypothetical protein 0.0351 0.3532 0.4682
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.065 0.063
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0326
Wolbachia endosymbiont of Brugia malayi dUTPase 0.0538 0.5453 1
Schistosoma mansoni hypothetical protein 0.0494 0.5004 0.5878
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.069 0.0789
Loa Loa (eye worm) hypothetical protein 0.0019 0.0114 0.0131
Schistosoma mansoni jumonji domain containing protein 0.0071 0.065 0.0742
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0326
Plasmodium vivax SET domain protein, putative 0.0037 0.0298 0.0344
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0447 0.0935
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0114 0.0093
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0114 0.0131
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0114 0.0093
Chlamydia trachomatis deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0538 0.5453 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0051 0.0447 0.0935
Mycobacterium tuberculosis Conserved hypothetical protein 0.0192 0.1897 1
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0114 0.0109
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0114 0.0109
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0051 0.0447 0.0935
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0043 0.0026
Mycobacterium ulcerans hypothetical protein 0.0192 0.1897 1
Loa Loa (eye worm) dUTP diphosphatase 0.0538 0.5453 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1696 0.4444
Plasmodium vivax deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0538 0.5453 1
Echinococcus granulosus phd:f box containing protein 0.0019 0.0114 0.0109
Mycobacterium leprae PROBABLE DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE DCD (DCTP DEAMINASE) 0.0187 0.1841 0.5
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0114 0.0109
Brugia malayi jmjC domain containing protein 0.0073 0.0671 0.1162
Echinococcus granulosus cpg binding protein 0.0037 0.0296 0.0324
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0114 0.0093
Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0538 0.5453 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0671 0.116
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0276 0.0431
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5004 0.4993
Entamoeba histolytica hypothetical protein 0.0538 0.5453 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0134 0.0133
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0671 0.0766
Loa Loa (eye worm) hypothetical protein 0.0037 0.0298 0.0471
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0298 0.0344
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0114 0.0131
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0538 0.5453 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0365 0.3674 1
Trichomonas vaginalis deoxyuridine 5'-triphosphate nucleotidohydrolase, putative 0.0538 0.5453 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0298 0.0277
Onchocerca volvulus 0.0037 0.0298 0.0084
Schistosoma mansoni deoxyuridine 5'-triphosphate nucleotidohydrolase 0.0538 0.5453 0.6408
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0071 0.065 0.063
Echinococcus granulosus dUTP pyrophosphatase 0.0538 0.5453 0.6408
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0277 0.0301
Leishmania major mitochondrial DNA polymerase beta 0.0365 0.3674 1
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0538 0.5453 1
Onchocerca volvulus 0.0287 0.2872 1
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0538 0.5453 1
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5004 0.5878
Echinococcus multilocularis muscleblind protein 1 0.018 0.1776 0.1758
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0538 0.5453 1
Schistosoma mansoni microtubule-associated protein tau 0.0833 0.8498 1
Trichomonas vaginalis set domain proteins, putative 0.0287 0.2872 0.5266
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0298 0.0277
Echinococcus multilocularis muscleblind protein 0.018 0.1776 0.1758
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.2514 0.4567
Entamoeba histolytica hypothetical protein 0.0538 0.5453 1
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0173 0.1696 0.4444
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0114 0.0109
Loa Loa (eye worm) hypothetical protein 0.0019 0.0114 0.0131
Treponema pallidum deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) 0.0538 0.5453 0.5
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.0538 0.5453 1
Entamoeba histolytica hypothetical protein 0.0351 0.3532 0.4682
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0114 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0326
Brugia malayi Muscleblind-like protein 0.018 0.1776 0.3205
Brugia malayi CXXC zinc finger family protein 0.0035 0.0276 0.0433
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0114 0.0109
Echinococcus multilocularis microtubule associated protein 2 0.0833 0.8498 0.8495
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial precursor, putative 0.0538 0.5453 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0365 0.3674 1
Brugia malayi jmjC domain containing protein 0.0019 0.0114 0.0134
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0609 0.0927
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0114 0.0093
Loa Loa (eye worm) hypothetical protein 0.018 0.1776 0.3203
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0114 0.0109

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (binding) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 15.8489 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 997 ] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human alpha-Glucosidase as a Potential Chaperone Treatment of Pompe Disease. (Class of assay: confirmatory) [Related pubchem assays: 1467, 2100, 2112, 1473, 1466 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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