Detailed information for compound 1475230

Basic information

Technical information
  • TDR Targets ID: 1475230
  • Name: ethyl 4-carbamoyl-5-methyl-3-(4,5,6,7-tetrahy dro-3H-azepin-2-ylamino)thiophene-2-carboxyla te
  • MW: 323.411 | Formula: C15H21N3O3S
  • H donors: 2 H acceptors: 2 LogP: 1.85 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1sc(c(c1NC1=NCCCCC1)C(=O)N)C
  • InChi: 1S/C15H21N3O3S/c1-3-21-15(20)13-12(11(14(16)19)9(2)22-13)18-10-7-5-4-6-8-17-10/h3-8H2,1-2H3,(H2,16,19)(H,17,18)
  • InChiKey: CWOLYEAWYFDDKD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-carbamoyl-5-methyl-3-(4,5,6,7-tetrahydro-3H-azepin-2-ylamino)-2-thiophenecarboxylic acid ethyl ester
  • 4-carbamoyl-5-methyl-3-(4,5,6,7-tetrahydro-3H-azepin-2-ylamino)thiophene-2-carboxylic acid ethyl ester
  • ethyl 4-aminocarbonyl-5-methyl-3-(4,5,6,7-tetrahydro-3H-azepin-2-ylamino)thiophene-2-carboxylate
  • MLS000039223
  • SMR000036373
  • AH-262/37288015
  • ZINC00478659
  • ZINC00478660
  • STOCK1S-42598

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 2 Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma congolense ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR015063,Domain of unknown function DUF1873,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei gambiense ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum IPR001394,Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2,domain-containing Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania infantum ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium hominis ubiquitin specific protease 66 Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania mexicana ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum ko:K01072 ubiquitin thiolesterase [EC3.1.2.15], putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 Get druggable targets OG5_127431 All targets in OG5_127431
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Cryptosporidium parvum ubiquitin C-terminal hydrolase of the cysteine proteinase fold Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum Ubiquitin carboxyl-terminal hydrolase 8, putative Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Candida albicans ubiquitin-specific protease Get druggable targets OG5_127431 All targets in OG5_127431
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus ubiquitin specific protease 41 Get druggable targets OG5_127431 All targets in OG5_127431
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein Get druggable targets OG5_127431 All targets in OG5_127431
Leishmania donovani ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Schistosoma japonicum expressed protein Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 Get druggable targets OG5_127431 All targets in OG5_127431
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_127431 All targets in OG5_127431
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Leishmania braziliensis ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative Get druggable targets OG5_127431 All targets in OG5_127431
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Plasmodium falciparum ubiquitin specific protease, putative ubiquitin specific peptidase 2 362 aa 378 aa 25.7 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis aldo keto reductase 0.0033 0.0056 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0358 0.0358
Mycobacterium tuberculosis Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) 0.0574 0.75 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Brugia malayi Muscleblind-like protein 0.018 0.208 0.208
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0212 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0212 0.0212
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0756 1 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0045 0.0212 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0045 0.0212 0.0212
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0033 0.0056 0.2652
Mycobacterium leprae Isocitrate lyase 0.0269 0.3302 0.436
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0045 0.0212 0.0212
Echinococcus granulosus aldo keto reductase 0.0033 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0212 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase 0.0033 0.0056 0.0056
Toxoplasma gondii aldose reductase, putative 0.0033 0.0056 1
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0756 1 1
Loa Loa (eye worm) oxidoreductase 0.0033 0.0056 0.0056
Mycobacterium leprae PROBABLE ISOCITRATE LYASE AceA (ISOCITRASE) (ISOCITRATASE) (ICL) 0.0574 0.75 1
Mycobacterium tuberculosis Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) 0.0574 0.75 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0358 0.0358
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0045 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0033 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.018 0.208 0.208
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0358 0.0358
Leishmania major prostaglandin f synthase, putative 0.0033 0.0056 0.2652
Onchocerca volvulus 0.0033 0.0056 0.5
Schistosoma mansoni pol-related 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0358 0.0358
Echinococcus granulosus ubiquitin specific protease 41 0.0045 0.0212 0.0212
Onchocerca volvulus 0.0033 0.0056 0.5
Onchocerca volvulus 0.0033 0.0056 0.5
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0212 0.0212
Loa Loa (eye worm) oxidoreductase 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase 0.0033 0.0056 0.0056
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0045 0.0212 1
Echinococcus multilocularis muscleblind protein 1 0.018 0.208 0.208
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0756 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0212 1
Loa Loa (eye worm) oxidoreductase 0.0033 0.0056 0.0056
Mycobacterium tuberculosis Isocitrate lyase Icl (isocitrase) (isocitratase) 0.0574 0.75 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0358 0.0358
Trypanosoma cruzi aldo/keto reductase, putative 0.0033 0.0056 0.2652
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0358 0.0358
Echinococcus granulosus hypothetical protein 0.0033 0.0056 0.0056
Plasmodium falciparum carbonic anhydrase 0.0029 0 0.5
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0212 1
Mycobacterium ulcerans isocitrate lyase AceAb 0.0574 0.75 1
Loa Loa (eye worm) oxidoreductase 0.0033 0.0056 0.0056
Schistosoma mansoni aldo-keto reductase 0.0033 0.0056 0.0056
Trypanosoma brucei prostaglandin f synthase 0.0033 0.0056 0.2652
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0045 0.0212 0.0212
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0756 1 1
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Echinococcus granulosus muscleblind protein 0.018 0.208 0.208
Leishmania major aldo-keto reductase-like protein 0.0033 0.0056 0.2652
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0358 0.0358
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0045 0.0212 0.0212
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0045 0.0212 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0358 0.0358
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0358 0.0358
Schistosoma mansoni aldo-keto reductase 0.0033 0.0056 0.0056
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0045 0.0212 1
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0033 0.0056 0.2652
Onchocerca volvulus 0.0033 0.0056 0.5
Trypanosoma brucei aldo-keto reductase, putative 0.0033 0.0056 0.2652
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis muscleblind protein 0.018 0.208 0.208
Mycobacterium ulcerans isocitrate lyase Icl 0.0574 0.75 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0056 0.0056
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.018 0.208 0.208
Echinococcus multilocularis aldo keto reductase 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0033 0.0056 0.0056
Onchocerca volvulus 0.0033 0.0056 0.5
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0056 0.0056
Echinococcus multilocularis ubiquitin specific protease 41 0.0045 0.0212 0.0212
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0045 0.0212 1
Trypanosoma cruzi aldo-keto reductase 0.0033 0.0056 0.2652
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0033 0.0056 0.0056
Onchocerca volvulus 0.0033 0.0056 0.5
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0033 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0045 0.0212 0.0212
Loa Loa (eye worm) oxidoreductase 0.0033 0.0056 0.0056

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a Using CHOP2 as the Reporter. (Class of assay: confirmatory) [Related pubchem assays: 2281 (Summary of qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a), 463106 (LOPAC Validation Assay for Inhibitors of Ubiquitin-specific Protease USP2a)] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 14.1254 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 20.5962 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. qHTS Assay for Activators of ClpP. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 31.6228 uM PubChem BioAssay. Inhibitors of Secretory Acid Sphingomyelinase (S-ASM): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 37.933 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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