Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7518 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0912 | 0.7518 | 0.7518 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Onchocerca volvulus | Notchless protein homolog | 0.0231 | 0.1059 | 0.5 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | Proteasome subunit A N-terminal signature/Proteasome subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.1174 | 1 | 1 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit alpha type-1, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0565 | 0.4229 | 0.4229 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.1174 | 1 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.4229 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.3546 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.4229 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0912 | 0.7518 | 0.7518 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.1174 | 1 | 1 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.0231 | 0.1059 | 0.1059 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.1174 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 1 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.1174 | 1 | 1 |
Schistosoma mansoni | proteasome subunit alpha 6 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0565 | 0.4229 | 0.3546 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.0231 | 0.1059 | 0.1059 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0912 | 0.7518 | 0.7224 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0912 | 0.7518 | 0.7224 |
Brugia malayi | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.1174 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.4229 |
Brugia malayi | 20S proteasome alpha5 subunit | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | ATP-dependent protease subunit HslV, putative | 0.0231 | 0.1059 | 0.1059 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0912 | 0.7518 | 0.7224 |
Brugia malayi | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0912 | 0.7518 | 0.7518 |
Schistosoma mansoni | proteasome subunit alpha 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0565 | 0.4229 | 0.4229 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0231 | 0.1059 | 0.5 |
Trypanosoma brucei | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma brucei | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome subunit alpha type 7-1 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 5 subunit, putative | 0.1174 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.1174 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7518 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.1174 | 1 | 1 |
Trypanosoma brucei | proteasome alpha 7 subunit | 0.0231 | 0.1059 | 0.1059 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0565 | 0.4229 | 0.3546 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.1174 | 1 | 1 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.1174 | 1 | 1 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 4 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0912 | 0.7518 | 0.7224 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit beta type 3 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome catalytic subunit 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | ATP-dependent protease subunit HslV | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit alpha 4 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.0231 | 0.1059 | 0.1059 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7224 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.3546 |
Trypanosoma brucei | proteasome beta 7 subunit | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.3546 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.1174 | 1 | 1 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0565 | 0.4229 | 0.3546 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 4 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Mycobacterium ulcerans | proteasome PrcB | 0.1174 | 1 | 1 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0565 | 0.4229 | 0.3546 |
Schistosoma mansoni | proteasome subunit alpha 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.1174 | 1 | 1 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0565 | 0.4229 | 0.4229 |
Echinococcus granulosus | proteasome subunit beta t family | 0.0231 | 0.1059 | 0.1059 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.1174 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0912 | 0.7518 | 0.7518 |
Schistosoma mansoni | proteasome subunit alpha 7 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma cruzi | hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain | 0.1174 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0912 | 0.7518 | 0.7224 |
Leishmania major | proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 3 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | PAS-3 protein | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.1174 | 1 | 1 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.