Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0912 | 0.7518 | 0.7224 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome catalytic subunit 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.0231 | 0.1059 | 0.1059 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0912 | 0.7518 | 0.7224 |
Trypanosoma brucei | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit alpha 6 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0912 | 0.7518 | 0.7518 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.3546 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0231 | 0.1059 | 0.5 |
Schistosoma mansoni | proteasome subunit alpha 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0565 | 0.4229 | 0.4229 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit beta type 3 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 7 subunit | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0912 | 0.7518 | 0.7518 |
Trypanosoma brucei | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0912 | 0.7518 | 0.7224 |
Schistosoma mansoni | proteasome subunit alpha 7 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0912 | 0.7518 | 0.7224 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.0231 | 0.1059 | 0.1059 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.3546 |
Leishmania major | proteasome beta 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | ATP-dependent protease subunit HslV, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | 20S proteasome alpha5 subunit | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit alpha type-1, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0565 | 0.4229 | 0.3546 |
Brugia malayi | proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma brucei | ATP-dependent protease subunit HslV | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | PAS-3 protein | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit alpha 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0565 | 0.4229 | 0.4229 |
Onchocerca volvulus | Notchless protein homolog | 0.0231 | 0.1059 | 0.5 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0565 | 0.4229 | 0.3546 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0565 | 0.4229 | 0.4229 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.3546 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome catalytic subunit 1 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta-1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome subunit beta t family | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.4229 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0565 | 0.4229 | 0.3546 |
Schistosoma mansoni | proteasome subunit alpha 4 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | Proteasome subunit alpha type 7-1 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7518 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0912 | 0.7518 | 0.7518 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0565 | 0.4229 | 0.4229 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0565 | 0.4229 | 0.4229 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0565 | 0.4229 | 0.4229 |
Trypanosoma brucei | Proteasome subunit A N-terminal signature/Proteasome subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome alpha 1 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7224 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.0231 | 0.1059 | 0.1059 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0912 | 0.7518 | 0.7224 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 4 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.0231 | 0.1059 | 0.1059 |
Schistosoma mansoni | proteasome subunit beta 4 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome beta 7 subunit | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma brucei | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 3 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0565 | 0.4229 | 0.3546 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0912 | 0.7518 | 0.7518 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.0231 | 0.1059 | 0.1059 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0231 | 0.1059 | 0.1059 |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit alpha type 1 | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0231 | 0.1059 | 0.1059 |
Brugia malayi | proteasome subunit beta type 1 | 0.0912 | 0.7518 | 0.7518 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0231 | 0.1059 | 0.1059 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0912 | 0.7518 | 0.7518 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0231 | 0.1059 | 0.1059 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.