Detailed information for compound 1551300

Basic information

Technical information
  • TDR Targets ID: 1551300
  • Name: N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)acetami de
  • MW: 273.714 | Formula: C15H12ClNO2
  • H donors: 2 H acceptors: 2 LogP: 2.24 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Nc1cc2C(O)c3c(c2cc1Cl)cccc3
  • InChi: 1S/C15H12ClNO2/c1-8(18)17-14-7-12-11(6-13(14)16)9-4-2-3-5-10(9)15(12)19/h2-7,15,19H,1H3,(H,17,18)
  • InChiKey: CASGYINMONDDLS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)ethanamide
  • 6955-66-4
  • NSC67678
  • NCIOpen2_003495
  • Acetamide, N-(3-chloro-9-hydroxy-9H-fluoren-2-yl)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0229 0.2864 0.4211
Schistosoma mansoni 26s proteasome non-ATPase regulatory subunit 4 0.0042 0.0072 0.0051
Trichomonas vaginalis 26S proteasome subunit, putative 0.006 0.0334 0.0491
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.026 0.3323 0.3309
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Toxoplasma gondii proteasome beta subunit 0.0249 0.3167 0.3153
Leishmania major proteasome regulatory non-ATP-ase subunit 5, putative,19S proteasome regulatory subunit 0.0065 0.0418 0.0614
Brugia malayi PCI domain containing protein 0.006 0.0334 0.0313
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0493 0.6801 1
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0197 0.2385 0.3486
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0262 0.3351 0.4927
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 2 0.0077 0.0589 0.0865
Brugia malayi Proteasome regulatory particle, non-atpase-like protein 6 0.0072 0.0517 0.0497
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Plasmodium vivax 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Echinococcus multilocularis DSS1 (SEM1) domain containing protein 0.0173 0.2023 0.2023
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0264 0.3386 0.3372
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0283 0.3674 0.5402
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.026 0.3323 0.4887
Plasmodium vivax 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Echinococcus multilocularis proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Echinococcus granulosus 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Echinococcus granulosus 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0238 0.3005 0.4419
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Toxoplasma gondii Mov34/MPN/PAD-1 family protein 0.006 0.0338 0.0318
Brugia malayi Probable 26S protease regulatory subunit 4 0.004 0.0038 0.0017
Trypanosoma brucei proteasome regulatory ATPase subunit 2 0.004 0.0038 0.0056
Giardia lamblia Proteasome subunit beta type 2 0.0249 0.3167 0.4658
Loa Loa (eye worm) RPT-2 protein 0.004 0.0038 0.0038
Plasmodium falciparum 26S proteasome regulatory subunit RPN3, putative 0.0077 0.0598 0.085
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Giardia lamblia Hypothetical protein 0.0072 0.0517 0.076
Trichomonas vaginalis 26S proteasome regulatory subunit S3, putative 0.0042 0.0073 0.0107
Echinococcus multilocularis 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Toxoplasma gondii PCI domain-containing protein 0.006 0.0334 0.0313
Trypanosoma cruzi 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Plasmodium vivax proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Plasmodium vivax proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Plasmodium vivax 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 3 0.0077 0.0598 0.0879
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0283 0.3674 0.5402
Plasmodium vivax proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Toxoplasma gondii proteasome subunit beta type, putative 0.0493 0.6801 0.6794
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0039 0.0021 0.0031
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0246 0.3118 0.3103
Entamoeba histolytica proteasome regulatory subunit, putative 0.0077 0.0598 0.085
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0249 0.3167 0.4641
Plasmodium falciparum 26S proteasome regulatory subunit RPN7, putative 0.0065 0.0414 0.058
Giardia lamblia 26S protease regulatory subunit 7 0.0039 0.0021 0.0031
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0493 0.6801 0.6794
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0065 0.0414 0.0394
Plasmodium falciparum 26S protease regulatory subunit 6B, putative 0.004 0.0038 0.0025
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Plasmodium falciparum 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0304 0.398 0.5852
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0271 0.3485 0.3471
Echinococcus multilocularis proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Echinococcus granulosus DSS1 SEM1 domain containing protein 0.0173 0.2023 0.2023
Brugia malayi proteasome subunit alpha type 3 0.0264 0.3386 0.3372
Leishmania major proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.0042 0.0074 0.0108
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0246 0.3118 0.3103
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 9 0.006 0.0334 0.0491
Loa Loa (eye worm) proteasome subunit beta type 1 0.0304 0.398 0.398
Plasmodium falciparum 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Trypanosoma brucei proteasome beta 7 subunit 0.0246 0.3118 0.4585
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Echinococcus granulosus 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.006 0.0334 0.0491
Echinococcus granulosus 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Onchocerca volvulus 0.004 0.0038 0.0027
Schistosoma mansoni 26S proteasome regulatory subunit rpn2 0.0052 0.0216 0.0195
Leishmania major proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Onchocerca volvulus 0.004 0.0038 0.0027
Trypanosoma brucei 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Plasmodium vivax 26S proteasome regulatory subunit RPN13, putative 0.011 0.1089 0.1575
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0285 0.3702 0.5429
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0065 0.0414 0.0609
Giardia lamblia 20S proteasome alpha subunit 7 0.0264 0.3386 0.4979
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 7 0.0065 0.0414 0.0609
Plasmodium falciparum proteasome subunit beta type-5 0.0493 0.6801 1
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.026 0.3323 0.4871
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Toxoplasma gondii 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0017
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Toxoplasma gondii proteasome subunit 0.0262 0.3351 0.3336
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0304 0.398 0.398
Echinococcus multilocularis adhesion regulating molecule 1 0.0707 1 1
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0246 0.3118 0.3118
Echinococcus multilocularis 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0589
Loa Loa (eye worm) 26S protease regulatory subunit 6A 0.0042 0.0074 0.0074
Giardia lamblia 20S proteasome alpha subunit 5 0.0283 0.3674 0.5402
Echinococcus granulosus adhesion regulating molecule 1 0.0707 1 1
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0358 0.4791 0.478
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0358 0.4791 0.7035
Leishmania major proteasome beta 2 subunit, putative 0.0249 0.3167 0.4658
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Trypanosoma brucei proteasome regulatory non-ATPase subunit 6 0.0072 0.0517 0.076
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0304 0.398 0.5839
Toxoplasma gondii PCI domain-containing protein 0.0072 0.0517 0.0497
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0261 0.3338 0.3338
Echinococcus granulosus Proteasome subunit alpha beta 0.0264 0.3386 0.3386
Plasmodium vivax proteasome subunit beta type-4, putative 0.0246 0.3118 0.4568
Plasmodium falciparum 26S proteasome regulatory subunit p55, putative 0.0065 0.0418 0.0585
Giardia lamblia 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0609
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 4 0.0042 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0039 0.0021 0.0021
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Echinococcus granulosus proteasome subunit beta type 6 0.0262 0.3351 0.3351
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Echinococcus granulosus 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Trypanosoma brucei proteasome beta 6 subunit 0.0304 0.398 0.5852
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Brugia malayi proteasome subunit beta type 2 0.0249 0.3167 0.3153
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Echinococcus multilocularis proteasome (prosome, macropain) 0.0493 0.6801 0.6801
Loa Loa (eye worm) proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0119
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Giardia lamblia Proteasome subunit beta type 1 0.0304 0.398 0.5852
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0261 0.3338 0.3324
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Giardia lamblia 26S proteasome ATPase subunit S4, putative 0.004 0.0038 0.0056
Leishmania major proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Loa Loa (eye worm) hypothetical protein 0.0424 0.5774 0.5774
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0338
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.3005 0.4419
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0249 0.3167 0.3167
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0493 0.6801 0.6801
Loa Loa (eye worm) hypothetical protein 0.0707 1 1
Brugia malayi proteasome subunit alpha type 1 0.026 0.3323 0.3309
Leishmania major proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Toxoplasma gondii 26s proteasome regulatory complex subunit, putative 0.0065 0.0414 0.0394
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 9, putative 0.006 0.0334 0.0491
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.026 0.3323 0.4887
Echinococcus granulosus Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0238 0.3005 0.4419
Trichomonas vaginalis 26S protease regulatory subunit, putative 0.004 0.0038 0.0056
Trypanosoma cruzi serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Leishmania major proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0249 0.3167 0.3153
Toxoplasma gondii adhesion regulating molecule region protein, putative 0.0707 1 1
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0261 0.3338 0.4892
Plasmodium vivax 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Leishmania major 26S protease regulatory subunit, putative,serine peptidase, Clan SJ, family S16, putative 0.0039 0.0021 0.0031
Brugia malayi Proteasome A-type and B-type family protein 0.0246 0.3118 0.3103
Plasmodium vivax 26S proteasome regulatory subunit RPN8, putative 0.006 0.0338 0.0468
Toxoplasma gondii PCI domain-containing protein 0.0077 0.0598 0.0578
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 7, putative 0.0058 0.0308 0.0453
Loa Loa (eye worm) hypothetical protein 0.0057 0.0293 0.0293
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Giardia lamblia 26S protease regulatory subunit 6B 0.004 0.0038 0.0056
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Trypanosoma cruzi proteasome regulatory ATPase subunit 5, putative 0.0042 0.0074 0.0108
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0318
Schistosoma mansoni 26S protease regulatory subunit 0.004 0.0038 0.0017
Plasmodium falciparum 26S protease regulatory subunit 6A, putative 0.0042 0.0074 0.0077
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Toxoplasma gondii SAC3/GANP family protein 0.0057 0.0293 0.0272
Brugia malayi Proteasome subunit alpha type 7-1 0.0358 0.4791 0.478
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Echinococcus granulosus proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Toxoplasma gondii hypothetical protein 0.0052 0.0228 0.0207
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0249 0.3167 0.4641
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Echinococcus multilocularis 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0197 0.2385 0.3486
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 7 0.006 0.0338 0.0338
Trichomonas vaginalis 26S protease regulatory subunit S10b, putative 0.0039 0.0021 0.0031
Trypanosoma cruzi proteasome regulatory non-ATP-ase subunit 5, putative 0.0065 0.0418 0.0614
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0493 0.6801 1
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0197 0.2385 0.3506
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Schistosoma mansoni hypothetical protein 0.0424 0.5774 0.5764
Brugia malayi proteasome subunit alpha type 6 0.0285 0.3702 0.3688
Trypanosoma brucei proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.006 0.0338 0.0318
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 7, putative 0.0065 0.0414 0.0609
Trypanosoma cruzi proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Trypanosoma brucei proteasome regulatory ATPase subunit 3 0.004 0.0038 0.0056
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0271 0.3485 0.5109
Trypanosoma brucei protease regulatory ATPase subunit 4 0.0039 0.0021 0.0031
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0358 0.4791 0.7045
Trypanosoma cruzi 20S proteasome subunit 0.0249 0.3167 0.4658
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0249 0.3167 0.4641
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Echinococcus granulosus 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Plasmodium vivax 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Loa Loa (eye worm) proteasome subunit alpha type 1 0.026 0.3323 0.3323
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0261 0.3338 0.4908
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Loa Loa (eye worm) RPN-3 protein 0.0077 0.0598 0.0598
Leishmania major proteasome regulatory ATPase subunit 2, putative 0.004 0.0038 0.0056
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0261 0.3338 0.3338
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Schistosoma mansoni adhesion regulating molecule 1 (110 kD cell membrane glycoprotein) 0.0707 1 1
Toxoplasma gondii 26s proteasome subunit p55, putative 0.0065 0.0418 0.0397
Loa Loa (eye worm) PCI domain-containing protein 0.0065 0.0418 0.0418
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0246 0.3118 0.4585
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Trypanosoma brucei 26S proteasome regulatory non-ATPase subunit 0.0077 0.0589 0.0865
Trypanosoma cruzi 19S proteasome regulatory subunit 0.0039 0.0021 0.0031
Leishmania major proteasome regulatory non-ATP-ase subunit, putative 0.0057 0.0293 0.0431
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0197 0.2385 0.3486
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Toxoplasma gondii proteasome 26S regulatory subunit 0.0041 0.0055 0.0034
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.006 0.0338 0.0468
Leishmania major proteasome beta 7 subunit, putative 0.0246 0.3118 0.4585
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0246 0.3118 0.4585
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0249 0.3167 0.4658
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.026 0.3323 0.4887
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0304 0.398 0.3967
Leishmania major hypothetical protein, conserved 0.0368 0.4943 0.7268
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0262 0.3351 0.4927
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0264 0.3386 0.4979
Schistosoma mansoni proteasome regulatory subunit-related 0.0065 0.0418 0.0397
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.026 0.3323 0.3309
Leishmania major proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Brugia malayi PCI domain containing protein 0.0065 0.0418 0.0397
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Giardia lamblia 20S proteasome alpha subunit 6 0.026 0.3323 0.4887
Plasmodium vivax 26S proteasome regulatory subunit RPN1, putative 0.0077 0.0589 0.0837
Leishmania major proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0261 0.3338 0.4908
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0197 0.2385 0.3506
Plasmodium vivax 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Plasmodium vivax proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Schistosoma mansoni 26S protease regulatory subunit 6a 0.0042 0.0074 0.0052
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0197 0.2385 0.2368
Toxoplasma gondii proteasome subunit alpha1, putative 0.0285 0.3702 0.3688
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Brugia malayi 26S proteasome non-ATPase regulatory subunit 7, putative 0.006 0.0338 0.0318
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0238 0.3005 0.299
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Brugia malayi Proteasome A-type and B-type family protein 0.0493 0.6801 0.6794
Plasmodium falciparum 26S proteasome regulatory subunit RPN9, putative 0.006 0.0334 0.0461
Schistosoma mansoni 26S proteasome non-ATPase regulatory subunit 0.0057 0.0293 0.0272
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Echinococcus multilocularis proteasome subunit beta type 6 0.0262 0.3351 0.3351
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0072 0.0517 0.0517
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0246 0.3118 0.3118
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0057 0.0293 0.0431
Schistosoma mansoni multiubiquitin binding protein S5a 0.0042 0.0072 0.0051
Trypanosoma cruzi 26S proteasome regulatory non-ATPase subunit, putative 0.0041 0.0055 0.0082
Plasmodium vivax 26S proteasome regulatory subunit RPN6, putative 0.0072 0.0517 0.0731
Giardia lamblia 20S proteasome alpha subunit 1 0.0285 0.3702 0.5443
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0493 0.6801 1
Plasmodium falciparum proteasome subunit beta type-4 0.0246 0.3118 0.4568
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Leishmania major proteasome regulatory ATPase subunit 0.0039 0.0021 0.0031
Trypanosoma cruzi proteasome complex subunit Rpn13 ubiquitin receptor, putative 0.011 0.1089 0.1601
Schistosoma mansoni 26s proteasome regulatory particle subunit 0.0077 0.0589 0.0568
Toxoplasma gondii 26S proteasome regulatory subunit 6b, putative 0.004 0.0038 0.0017
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0358 0.4791 0.7045
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 5 0.0065 0.0418 0.0614
Onchocerca volvulus Notchless protein homolog 0.0264 0.3386 0.5493
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0705 0.9963 0.9963
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0249 0.3167 0.3167
Leishmania major proteasome alpha 1 subunit, putative 0.026 0.3323 0.4887
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0285 0.3702 0.3688
Trypanosoma brucei proteasome regulatory ATPase subunit 5 0.0042 0.0074 0.0108
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5387
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0271 0.3485 0.3471
Plasmodium falciparum 26S proteasome regulatory subunit RPN2, putative 0.0052 0.0216 0.0287
Entamoeba histolytica 26S protease regulatory subunit, putative 0.0042 0.0074 0.0077
Brugia malayi Proteasome A-type and B-type family protein 0.0262 0.3351 0.3336
Trypanosoma cruzi proteasome regulatory ATPase subunit 3, putative 0.004 0.0038 0.0056
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0197 0.2385 0.5
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0285 0.3702 0.5443
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0304 0.398 0.3967
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Toxoplasma gondii Proteasome/cyclosome repeat-containing protein 0.0052 0.0216 0.0195
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0264 0.3386 0.3386
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0493 0.6801 1
Entamoeba histolytica 19S cap proteasome S2 subunit 0.0041 0.0055 0.005
Leishmania major proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.026 0.3323 0.4871
Loa Loa (eye worm) 26S proteasome non-ATPase regulatory subunit 7 0.006 0.0338 0.0338
Echinococcus granulosus proteasome subunit beta type 7 0.0705 0.9963 0.9963
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0304 0.398 0.398
Loa Loa (eye worm) PAS-3 protein 0.0229 0.2858 0.2858
Giardia lamblia Proteasome subunit beta type 3 0.0249 0.3167 0.4658
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 0.0052 0.0216 0.0216
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 0.0057 0.0293 0.0431
Brugia malayi proteasome subunit alpha type 2 0.0271 0.3485 0.3471
Plasmodium vivax 26S proteasome AAA-ATPase subunit RPT3, putative 0.004 0.0038 0.0025
Entamoeba histolytica proteasome regulatory subunit, putative 0.0057 0.0293 0.0401
Toxoplasma gondii proteasome regulatory subunit 0.006 0.0338 0.0318
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Toxoplasma gondii proteasome subunit alpha type, putative 0.0261 0.3338 0.3324
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0262 0.3351 0.3336
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0246 0.3118 0.4568
Schistosoma mansoni 26S protease regulatory subunit 6b 0.004 0.0038 0.0017
Loa Loa (eye worm) 26S protease regulatory subunit 8 0.0039 0.0021 0.0021
Loa Loa (eye worm) proteasome Regulatory Particle 0.0065 0.0414 0.0414
Trypanosoma brucei proteasome regulatory non-ATP-ase subunit 2 0.0052 0.0216 0.0317
Brugia malayi 26S proteasome subunit P45 family protein 0.004 0.0038 0.0017
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0057 0.0293 0.0431
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0238 0.3005 0.4419
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Trypanosoma brucei Regulatory particle triple-A ATPase subunit 6 0.0039 0.0021 0.0031
Plasmodium falciparum 26S proteasome regulatory subunit RPN12, putative 0.0057 0.0293 0.0401
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0283 0.3674 0.5387
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 6 0.0065 0.0414 0.0394
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0493 0.6801 1
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0283 0.3674 0.366
Echinococcus multilocularis 26s protease regulatory subunit 6a 0.0042 0.0074 0.0074
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0197 0.2385 0.3506
Loa Loa (eye worm) hypothetical protein 0.004 0.0038 0.0038
Plasmodium vivax proteasome subunit beta type-6, putative 0.0262 0.3351 0.4911
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0493 0.6801 1
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0285 0.3702 0.5443
Loa Loa (eye worm) proteasome subunit beta type 2 0.0249 0.3167 0.3167
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0358 0.4791 0.4791
Giardia lamblia 20S proteasome alpha subunit 2 0.0271 0.3485 0.5124
Echinococcus granulosus proteasome prosome macropain 0.0493 0.6801 0.6801
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0493 0.6801 1
Trichomonas vaginalis 26S proteasome subunit S9, putative 0.0072 0.0517 0.076
Echinococcus granulosus proteasome subunit beta t family 0.0249 0.3167 0.3167
Entamoeba histolytica hypothetical protein 0.0052 0.0216 0.0287
Toxoplasma gondii heat shock protein hslv, putative 0.0197 0.2385 0.2368
Echinococcus granulosus 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0598
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.026 0.3323 0.3323
Loa Loa (eye worm) hypothetical protein 0.0052 0.0228 0.0228
Toxoplasma gondii proteasome subunit alpha type, putative 0.0161 0.1851 0.1834
Trichomonas vaginalis 26S protease regulatory subunit 6A, putative 0.004 0.0038 0.0056
Schistosoma mansoni hypothetical protein 0.0173 0.2023 0.2006
Plasmodium vivax 26S protease regulatory subunit 6a, putative 0.0042 0.0074 0.0077
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0264 0.3386 0.4979
Brugia malayi Proteasome A-type and B-type family protein 0.0705 0.9963 0.9963
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0283 0.3674 0.5402
Plasmodium falciparum 26S proteasome regulatory subunit RPN6 0.0072 0.0517 0.0731
Giardia lamblia 26S protease regulatory subunit 6A 0.0042 0.0074 0.0108
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0238 0.3005 0.4402
Toxoplasma gondii peptidase, T1 family protein 0.0264 0.3386 0.3372
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0262 0.3351 0.4927
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0238 0.3005 0.4402
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0264 0.3386 0.4963
Brugia malayi proteasome subunit beta type 1 0.0304 0.398 0.3967
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0246 0.3118 0.3118
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0249 0.3167 0.3153
Schistosoma mansoni 26S proteasome subunit S9 0.0072 0.0517 0.0497
Toxoplasma gondii 26S proteasome regulatory subunit, S6a family AAA ATpase 0.0042 0.0074 0.0052
Entamoeba histolytica proteasome regulatory subunit, putative 0.006 0.0334 0.0461
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0262 0.3351 0.4911
Echinococcus multilocularis 26S proteasome regulatory subunit N1 0.006 0.0334 0.0334
Schistosoma mansoni 26S proteasome regulatory subunit S3 0.0077 0.0598 0.0578
Brugia malayi Probable 26S proteasome non-ATPase regulatory subunit 3 0.0077 0.0598 0.0578
Entamoeba histolytica proteasome regulatory subunit, putative 0.0072 0.0517 0.0731
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Giardia lamblia 20S proteasome alpha subunit 3 0.0261 0.3338 0.4908
Leishmania major proteasome beta 5 subunit, putative 0.0493 0.6801 1
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Trypanosoma brucei proteasome alpha 7 subunit 0.0264 0.3386 0.4979
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0261 0.3338 0.4892
Brugia malayi Ubiquitin interaction motif family protein 0.0042 0.0072 0.0051
Giardia lamblia 20S proteasome alpha subunit 4 0.0358 0.4791 0.7045
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0249 0.3167 0.3153
Leishmania major proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Echinococcus granulosus proteasome subunit alpha type 2 0.0271 0.3485 0.3485
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0246 0.3118 0.4585
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 6 0.0065 0.0414 0.0414
Trypanosoma cruzi 19S proteasome non-atpase subunit 8 0.006 0.0338 0.0497
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.3005 0.3005
Brugia malayi proteasome subunit alpha type 4 0.0229 0.2858 0.2843
Onchocerca volvulus Proteasomal ubiquitin receptor ADRM1 homolog 0.0449 0.6146 1
Brugia malayi 26S proteasome non-ATPase regulatory subunit Nin1/mts3 family protein 0.0057 0.0293 0.0272
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0077 0.0589 0.0865
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Leishmania major proteasome regulatory non-ATP-ase subunit 8, putative,26S proteasome regulatory subunit, putative 0.006 0.0338 0.0497
Plasmodium falciparum 26S proteasome regulatory subunit RPN13, putative 0.0368 0.4943 0.7259
Echinococcus multilocularis 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038
Entamoeba histolytica proteasome regulatory subunit, putative 0.0042 0.0072 0.0074
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0283 0.3674 0.3674
Brugia malayi Proteasome subunit alpha type 1 0.0228 0.2844 0.2828
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0249 0.3167 0.3167
Leishmania major proteasome regulatory non-ATPase subunit 6, putative 0.0072 0.0517 0.076
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0262 0.3351 0.3351
Trichomonas vaginalis 26S proteasome non-ATPase regulatory subunit, putative 0.0042 0.0072 0.0106
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0271 0.3485 0.5109
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0414 0.058
Echinococcus multilocularis 26s protease regulatory subunit s10b 0.0039 0.0021 0.0021
Plasmodium vivax proteasome subunit beta type-1, putative 0.0304 0.398 0.5839
Brugia malayi 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0568
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0264 0.3386 0.3386
Echinococcus granulosus subfamily T1A non peptidase ue 0.0283 0.3674 0.3674
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0358 0.4791 0.7035
Giardia lamblia 26S protease regulatory subunit 8 0.0039 0.0021 0.0031
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0271 0.3485 0.5124
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0358 0.4791 0.4791
Echinococcus multilocularis proteasome subunit alpha type 6 0.0285 0.3702 0.3702
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0249 0.3167 0.4641
Trichomonas vaginalis cop9 signalosome complex subunit, putative 0.0065 0.0414 0.0609
Trichomonas vaginalis 26S proteasome regulatory subunit, putative 0.0045 0.0119 0.0176
Trichomonas vaginalis proteasome regulatory subunits, putative 0.0065 0.0418 0.0614
Schistosoma mansoni hypothetical protein 0.006 0.0334 0.0313
Plasmodium vivax proteasome subunit beta type-5, putative 0.0493 0.6801 1
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.006 0.0338 0.0338
Plasmodium falciparum 26S protease regulatory subunit 4, putative 0.004 0.0038 0.0025
Trichomonas vaginalis regulatory particle non-ATPase, putative 0.006 0.0334 0.0491
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0264 0.3386 0.4963
Loa Loa (eye worm) PCI domain-containing protein 0.006 0.0334 0.0334
Trypanosoma cruzi proteasome regulatory non-ATPase subunit, putative 0.0042 0.0072 0.0106
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0249 0.3167 0.4658
Entamoeba histolytica proteasome regulatory subunit, putative 0.0065 0.0418 0.0585
Entamoeba histolytica 26S protease regulatory subunit, putative 0.004 0.0038 0.0025
Echinococcus granulosus 26S proteasome non ATPase regulatory subunit 8 0.0057 0.0293 0.0293
Echinococcus multilocularis proteasome subunit beta type 7 0.0705 0.9963 0.9963
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0251 0.3194 0.318
Echinococcus multilocularis 26S proteasome non ATPase regulatory subunit 12 0.0065 0.0418 0.0418
Echinococcus granulosus proteasome 26s subunit subunit 4 atpase 0.004 0.0038 0.0038
Brugia malayi 20S proteasome alpha5 subunit 0.0283 0.3674 0.366
Loa Loa (eye worm) 26S proteasome regulatory complex subunit p97 0.0077 0.0589 0.0589
Loa Loa (eye worm) proteasome 26S subunit 0.0039 0.0021 0.0021
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0238 0.3005 0.4419
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0285 0.3702 0.5429
Brugia malayi Chain A, Structure Of A Brca2-Dss1 Complex. 0.0424 0.5774 0.5764
Leishmania major proteasome regulatory non-ATPase subunit, putative 0.0077 0.0589 0.0865
Mycobacterium ulcerans proteasome PrcB 0.0493 0.6801 1
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit, putative 0.006 0.0338 0.0468
Brugia malayi proteasome subunit beta type 3 0.0249 0.3167 0.3153
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0283 0.3674 0.366
Loa Loa (eye worm) proteasome regulatory particle 0.0072 0.0517 0.0517
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.006 0.0338 0.0468
Leishmania major proteasome regulatory non-ATP-ase subunit 3, putative 0.0077 0.0598 0.0879
Loa Loa (eye worm) proteasome subunit beta type 3 0.0249 0.3167 0.3167
Leishmania major proteasome regulatory ATPase subunittcc1l8.3, putative 0.004 0.0038 0.0056
Trichomonas vaginalis Clan MP, family M67, Poh1-like metallopeptidase 0.006 0.0338 0.0497
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0304 0.398 0.5852
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 3, putative 0.0077 0.0598 0.0879
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0249 0.3167 0.4658
Brugia malayi Proteasome/cyclosome repeat family protein 0.0045 0.0119 0.0098
Brugia malayi 26S protease regulatory subunit 6A 0.0042 0.0074 0.0052
Brugia malayi 26S proteasome regulatory subunit rpn11 0.006 0.0338 0.0318
Echinococcus granulosus 26S proteasome regulatory subunit T3 0.004 0.0038 0.0038

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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