Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | proteasome beta 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.057 | 0.4519 | 0.4519 |
Plasmodium vivax | proteasome subunit alpha type-1, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit alpha 1 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | proteasome beta 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.092 | 0.7643 | 0.7224 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.1184 | 1 | 1 |
Trypanosoma brucei | proteasome beta 7 subunit | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0233 | 0.1509 | 0.5 |
Leishmania major | proteasome alpha 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.1184 | 1 | 1 |
Onchocerca volvulus | Notchless protein homolog | 0.0233 | 0.1509 | 0.5 |
Echinococcus granulosus | proteasome prosome macropain subunit beta type | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | subfamily T1A non peptidase ue | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit beta type-6, putative | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit alpha type-5, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome subunit beta type 3 | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.1184 | 1 | 1 |
Brugia malayi | Proteasome subunit alpha type 7-1 | 0.0233 | 0.1509 | 0.0463 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Schistosoma mansoni | proteasome catalytic subunit 1 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Toxoplasma gondii | proteasome beta subunit | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit alpha type-2, putative | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.057 | 0.4519 | 0.4519 |
Brugia malayi | proteasome subunit alpha type 1 | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.057 | 0.4519 | 0.3546 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.1184 | 1 | 1 |
Echinococcus granulosus | proteasome subunit alpha type 2 | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.092 | 0.7643 | 0.7643 |
Mycobacterium ulcerans | proteasome PrcB | 0.1184 | 1 | 1 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit alpha type-3, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome alpha 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | ATP-dependent protease subunit HslV | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit beta type-7, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0233 | 0.1509 | 0.1509 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.057 | 0.4519 | 0.3546 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit alpha | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.1184 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.057 | 0.4519 | 0.3845 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.092 | 0.7643 | 0.7643 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.092 | 0.7643 | 0.7643 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.057 | 0.4519 | 0.4519 |
Brugia malayi | proteasome subunit beta type 3 | 0.0233 | 0.1509 | 0.0463 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Echinococcus granulosus | 20S proteasome subunit alpha 6 | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome subunit alpha type 6 | 0.0233 | 0.1509 | 0.1509 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.092 | 0.7643 | 0.7224 |
Trypanosoma cruzi | proteasome beta 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome catalytic subunit 2 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.1184 | 1 | 1 |
Echinococcus granulosus | Proteasome subunit alpha beta | 0.0233 | 0.1509 | 0.1509 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.1184 | 1 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.057 | 0.4519 | 0.3845 |
Loa Loa (eye worm) | proteasome subunit alpha type 7-1 | 0.0233 | 0.1509 | 0.0463 |
Echinococcus granulosus | calcium:calmodulin dependent 3'5' cyclic | 0.0186 | 0.1096 | 0.1096 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta-1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.1184 | 1 | 1 |
Echinococcus granulosus | proteasome subunit beta t family | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.092 | 0.7643 | 0.7643 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Toxoplasma gondii | proteasome subunit alpha type 1, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome subunit alpha type 1 | 0.0233 | 0.1509 | 0.0463 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Schistosoma mansoni | proteasome subunit beta 4 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome subunit alpha type-1, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | ATP-dependent protease subunit ClpQ, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome subunit alpha type-5, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome alpha 7 subunit | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit alpha 7 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | peptidase, T1 family protein | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit beta type 7 precursor, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.092 | 0.7643 | 0.7643 |
Brugia malayi | proteasome subunit alpha type 6 | 0.0233 | 0.1509 | 0.0463 |
Echinococcus multilocularis | proteasome subunit alpha type 2 | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome (prosome macropain) subunit beta type | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit alpha 6 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.092 | 0.7643 | 0.7224 |
Brugia malayi | proteasome subunit beta type 1 | 0.092 | 0.7643 | 0.7352 |
Trypanosoma brucei | proteasome alpha 1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | 20S proteasome subunit beta 7, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome subunit beta type 7 | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.057 | 0.4519 | 0.3546 |
Trypanosoma cruzi | ATP-dependent protease subunit HslV, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome beta 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit alpha type-4, putative | 0.0233 | 0.1509 | 0.1509 |
Plasmodium vivax | proteasome subunit alpha type-7, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.057 | 0.4519 | 0.3845 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome prosome macropain subunit alpha | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.1184 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.092 | 0.7643 | 0.7352 |
Plasmodium vivax | proteasome subunit beta type-3, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit alpha 2 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.1184 | 1 | 1 |
Brugia malayi | Proteasome subunit alpha type 1 | 0.0233 | 0.1509 | 0.0463 |
Loa Loa (eye worm) | proteasome subunit alpha type 6 | 0.0233 | 0.1509 | 0.0463 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.092 | 0.7643 | 0.7643 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.092 | 0.7643 | 0.7352 |
Echinococcus multilocularis | proteasome subunit beta type 6 | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome alpha 1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.057 | 0.4519 | 0.3546 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome prosome macropain | 0.1184 | 1 | 1 |
Trypanosoma cruzi | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.057 | 0.4519 | 0.4519 |
Toxoplasma gondii | proteasome subunit alpha1, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | 20s proteasome beta 7 subunit, (putative) | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta 2 subunit, putative | 0.057 | 0.4519 | 0.4519 |
Loa Loa (eye worm) | proteasome subunit alpha type 3 | 0.0233 | 0.1509 | 0.0463 |
Leishmania major | proteasome alpha 7 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome beta 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | PAS-3 protein | 0.0233 | 0.1509 | 0.0463 |
Echinococcus multilocularis | subfamily T1A non peptidase ue | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.092 | 0.7643 | 0.7643 |
Echinococcus multilocularis | Proteasome, subunit alpha beta | 0.0233 | 0.1509 | 0.1509 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.057 | 0.4519 | 0.3546 |
Brugia malayi | proteasome subunit beta type 2 | 0.057 | 0.4519 | 0.3845 |
Schistosoma mansoni | subfamily T1A non-peptidase homologue (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Echinococcus multilocularis | 20S proteasome subunit alpha 6 | 0.0233 | 0.1509 | 0.1509 |
Brugia malayi | proteasome subunit alpha type 3 | 0.0233 | 0.1509 | 0.0463 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.1184 | 1 | 1 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0233 | 0.1509 | 0.0463 |
Echinococcus multilocularis | Proteasome subunit alpha type 7 | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome beta 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome beta 5 subunit, putative | 0.1184 | 1 | 1 |
Schistosoma mansoni | proteasome subunit alpha 4 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Echinococcus multilocularis | calcium:calmodulin dependent 3',5' cyclic | 0.0186 | 0.1096 | 0.1096 |
Schistosoma mansoni | proteasome subunit beta 3 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Toxoplasma gondii | proteasome subunit alpha type 5-2, putative | 0.0233 | 0.1509 | 0.1509 |
Brugia malayi | proteasome subunit alpha type 2 | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.057 | 0.4519 | 0.4519 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.1184 | 1 | 1 |
Trypanosoma cruzi | proteasome alpha 1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma brucei | proteasome beta-1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome subunit beta type 7 | 0.0233 | 0.1509 | 0.1509 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.092 | 0.7643 | 0.7224 |
Toxoplasma gondii | proteasome subunit alpha type, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | 20S proteasome alpha5 subunit | 0.0233 | 0.1509 | 0.0463 |
Toxoplasma gondii | heat shock protein hslv, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus multilocularis | proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta | 0.0233 | 0.1509 | 0.1509 |
Brugia malayi | proteasome subunit alpha type 4 | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.092 | 0.7643 | 0.7643 |
Trypanosoma brucei | Proteasome subunit A N-terminal signature/Proteasome subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome beta-1 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome subunit alpha type-5, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.057 | 0.4519 | 0.4519 |
Echinococcus granulosus | proteasome subunit alpha type 6 | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | proteasome alpha 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.1184 | 1 | 1 |
Plasmodium vivax | proteasome subunit beta type-4, putative | 0.0233 | 0.1509 | 0.1509 |
Leishmania major | proteasome alpha 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | proteasome subunit alpha type 2 | 0.0233 | 0.1509 | 0.0463 |
Echinococcus granulosus | Proteasome subunit alpha type 7 | 0.0233 | 0.1509 | 0.1509 |
Brugia malayi | 20S proteasome alpha5 subunit | 0.0233 | 0.1509 | 0.0463 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.1184 | 1 | 1 |
Trypanosoma brucei | proteasome alpha 3 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Trypanosoma cruzi | 20S proteasome subunit | 0.057 | 0.4519 | 0.4519 |
Plasmodium vivax | proteasome subunit alpha type-6, putative | 0.0233 | 0.1509 | 0.1509 |
Schistosoma mansoni | proteasome subunit alpha 3 (T01 family) | 0.0233 | 0.1509 | 0.0463 |
Trypanosoma cruzi | proteasome alpha 2 subunit, putative | 0.0233 | 0.1509 | 0.1509 |
Echinococcus granulosus | proteasome subunit beta type 6 | 0.0233 | 0.1509 | 0.1509 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.