Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0005 | 0.0005 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0012 | 0.0084 | 0.0087 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Toxoplasma gondii | GDP-L-fucose synthetase | 0.0012 | 0.0084 | 0.0088 |
Echinococcus multilocularis | UDP glucose 4 epimerase | 0.0305 | 0.9596 | 1 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus multilocularis | NAD(P) binding domain | 0.0012 | 0.0084 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.5195 | 0.5414 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0011 | 0.0038 | 0.004 |
Loa Loa (eye worm) | oxidoreductase | 0.0012 | 0.0084 | 0.0088 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0088 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0011 | 0.0038 | 0.004 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0011 | 0.0038 | 0.0211 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.1801 | 1 |
Plasmodium falciparum | GDP-L-fucose synthase | 0.0012 | 0.0084 | 1 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0011 | 0.0038 | 0.004 |
Onchocerca volvulus | 0.0012 | 0.0084 | 1 | |
Mycobacterium ulcerans | hypothetical protein | 0.0012 | 0.0084 | 0.0467 |
Trypanosoma cruzi | NAD dependent epimerase/dehydratase family, putative | 0.0012 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.1166 | 0.1216 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0305 | 0.9596 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0011 | 0.0038 | 0.4515 |
Echinococcus multilocularis | 0.0012 | 0.0084 | 0.0087 | |
Mycobacterium leprae | Conserved hypothetical protein | 0.0011 | 0.0038 | 0.4515 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0038 | 0.004 |
Trypanosoma cruzi | NAD dependent epimerase/dehydratase family, putative | 0.0012 | 0.0084 | 0.0088 |
Schistosoma mansoni | NAD dependent epimerase/dehydratase | 0.0012 | 0.0084 | 0.0088 |
Giardia lamblia | Nuclear LIM interactor-interacting factor 1 | 0.0012 | 0.0084 | 0.0084 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus granulosus | UDP glucose 4 epimerase | 0.0305 | 0.9596 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0088 |
Echinococcus granulosus | NADH dehydrogenase ubiquinone 1 alpha | 0.0012 | 0.0084 | 0.0088 |
Trypanosoma brucei | L-threonine 3-dehydrogenase | 0.0012 | 0.0084 | 0.0084 |
Echinococcus granulosus | NADP binding domain | 0.0012 | 0.0084 | 0.0088 |
Toxoplasma gondii | UDP-glucose 4-epimerase | 0.0305 | 0.9596 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0038 | 0.004 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0011 | 0.0038 | 0.0211 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.001 | 0.0005 | 0.0005 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0038 | 0.004 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1166 | 0.1216 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.1166 | 0.1216 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | hypothetical protein | 0.0012 | 0.0084 | 0.0467 |
Mycobacterium ulcerans | UDP-glucose 4-epimerase GalE2 | 0.0012 | 0.0084 | 0.0467 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.1801 | 1 |
Trypanosoma brucei | Mitochondrial import inner membrane translocase subunit TIM50 | 0.0012 | 0.0084 | 0.0084 |
Plasmodium falciparum | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0084 | 0.9957 |
Trypanosoma cruzi | L-threonine 3-dehydrogenase, putative | 0.0012 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.003 | 0.067 | 0.0698 |
Mycobacterium ulcerans | oxidoreductase | 0.0012 | 0.0084 | 0.0467 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0079 | 0.0082 |
Brugia malayi | follicle stimulating hormone receptor | 0.0236 | 0.7346 | 0.7656 |
Onchocerca volvulus | 0.0012 | 0.0084 | 1 | |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0011 | 0.0038 | 0.0211 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0012 | 0.0084 | 0.0087 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Trypanosoma cruzi | L-threonine 3-dehydrogenase, putative | 0.0012 | 0.0084 | 0.0088 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0011 | 0.0038 | 0.004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1166 | 0.1216 |
Mycobacterium leprae | POSSIBLE UDP-GLUCOSE 4-EPIMERASE GALE2 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE | 0.0012 | 0.0084 | 1 |
Toxoplasma gondii | Dullard family phosphatase domain-containing protein | 0.0012 | 0.0084 | 0.0087 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0084 | 0.0088 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0065 | 0.1801 | 0.177 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.1166 | 0.1216 |
Mycobacterium ulcerans | UDP-glucose 4-epimerase | 0.0012 | 0.0084 | 0.0467 |
Echinococcus granulosus | Carboxy terminal domain RNA polymerase II | 0.0012 | 0.0084 | 0.0087 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0038 | 0.004 |
Trypanosoma brucei | UDP-galactose 4-epimerase | 0.0318 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1166 | 0.1216 |
Trichomonas vaginalis | dullard protein, putative | 0.0012 | 0.0084 | 0.0087 |
Brugia malayi | cytochrome P450 | 0.0011 | 0.0038 | 0.004 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 27 | 0.0012 | 0.0084 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Treponema pallidum | DNA ligase (lig) | 0.001 | 0 | 0.5 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus granulosus | GDP L fucose synthase | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium tuberculosis | Conserved protein | 0.0012 | 0.0084 | 0.0261 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0038 | 0.004 |
Brugia malayi | UDP galactose 4'-epimerase | 0.0305 | 0.9596 | 1 |
Echinococcus multilocularis | epimerase family protein sdr39u1 | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus granulosus | geminin | 0.017 | 0.5195 | 0.5414 |
Loa Loa (eye worm) | UDP galactose 4'-epimerase | 0.0305 | 0.9596 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.1166 | 0.1216 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0011 | 0.0038 | 0.0211 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0011 | 0.0038 | 0.0211 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0011 | 0.0038 | 0.004 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase | 0.0012 | 0.0084 | 0.0467 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0011 | 0.0038 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.0079 | 0.0082 |
Chlamydia trachomatis | DNA ligase | 0.001 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.001 | 0.0005 | 0.0005 |
Echinococcus multilocularis | geminin | 0.017 | 0.5195 | 0.5414 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0065 | 0.1801 | 0.1877 |
Onchocerca volvulus | 0.0012 | 0.0084 | 1 | |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0088 |
Trichomonas vaginalis | dullard protein, putative | 0.0012 | 0.0084 | 0.0087 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0011 | 0.0038 | 0.004 |
Echinococcus granulosus | CTD small phosphatase protein like | 0.0012 | 0.0084 | 0.0087 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0011 | 0.0038 | 0.004 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0012 | 0.0084 | 0.0087 |
Trypanosoma brucei | NAD dependent epimerase/dehydratase family, putative | 0.0012 | 0.0084 | 0.0084 |
Mycobacterium tuberculosis | Probable nucleotide-sugar epimerase EpiA | 0.0012 | 0.0084 | 0.0261 |
Onchocerca volvulus | 0.0012 | 0.0084 | 1 | |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0084 | 0.0261 |
Echinococcus multilocularis | 0.0011 | 0.0038 | 0.004 | |
Brugia malayi | Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 | 0.0012 | 0.0084 | 0.0087 |
Trichomonas vaginalis | dihydroflavonal-4-reductase, putative | 0.0012 | 0.0084 | 0.0088 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0084 | 0.9957 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0084 | 0.0087 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0011 | 0.0038 | 0.0211 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0088 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Mycobacterium ulcerans | UDP-glucose 4-epimerase | 0.0012 | 0.0084 | 0.0467 |
Trypanosoma cruzi | UDP-galactose 4-epimerase, putative | 0.0305 | 0.9596 | 1 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0305 | 0.9596 | 1 |
Mycobacterium tuberculosis | Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase | 0.0012 | 0.0084 | 0.0261 |
Brugia malayi | Cytochrome P450 family protein | 0.003 | 0.067 | 0.0698 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0011 | 0.0038 | 0.0211 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0011 | 0.0038 | 0.0038 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0065 | 0.1801 | 1 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0011 | 0.0038 | 0.0211 |
Mycobacterium ulcerans | oxidoreductase | 0.0012 | 0.0084 | 0.0467 |
Leishmania major | udp-glc 4-epimerase, putative | 0.0318 | 1 | 1 |
Plasmodium vivax | GDP-L-fucose synthase, putative | 0.0012 | 0.0084 | 1 |
Trypanosoma brucei | GDP-L-fucose synthetase | 0.0012 | 0.0084 | 0.0084 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0065 | 0.1801 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.1801 | 0.1877 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0851 | 0.0886 |
Trypanosoma cruzi | GDP-mannose 4,6 dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0236 | 0.7346 | 0.7656 |
Entamoeba histolytica | NLI interacting factor-like phosphatase domain-containing protein | 0.0012 | 0.0084 | 0.0087 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0012 | 0.0084 | 0.0088 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0851 | 0.0886 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0084 | 0.0088 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0065 | 0.1801 | 0.1877 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | nucleoside-diphosphate-sugar epimerase | 0.0012 | 0.0084 | 0.0467 |
Mycobacterium ulcerans | hypothetical protein | 0.0012 | 0.0084 | 0.0467 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1166 | 0.1216 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus granulosus | epimerase family protein sdr39u1 | 0.0012 | 0.0084 | 0.0088 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0012 | 0.0084 | 0.0087 |
Brugia malayi | GDP-L-fucose synthetase | 0.0012 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Possible dTDP-glucose 4,6-dehydratase | 0.0012 | 0.0084 | 0.0261 |
Toxoplasma gondii | NAD dependent epimerase/dehydratase family protein | 0.0012 | 0.0084 | 0.0088 |
Echinococcus multilocularis | GDP L fucose synthase | 0.0012 | 0.0084 | 0.0088 |
Wolbachia endosymbiont of Brugia malayi | nucleoside-diphosphate-sugar epimerase | 0.0012 | 0.0084 | 1 |
Trichomonas vaginalis | UDP-glucose 4-epimerase, putative | 0.0305 | 0.9596 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.1166 | 0.1216 |
Trypanosoma cruzi | GDP-L-fucose synthetase, putative | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0011 | 0.0038 | 0.0211 |
Brugia malayi | Cytochrome P450 family protein | 0.0011 | 0.0038 | 0.004 |
Plasmodium vivax | NLI interacting factor-like phosphatase, putative | 0.0012 | 0.0084 | 0.9957 |
Schistosoma mansoni | cytochrome P450 | 0.0011 | 0.0038 | 0.004 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0012 | 0.0084 | 0.0261 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0065 | 0.1801 | 0.1877 |
Entamoeba histolytica | UDP-glucose 4-epimerase, putative | 0.0305 | 0.9596 | 1 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0012 | 0.0084 | 0.0087 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0011 | 0.0038 | 0.0211 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0011 | 0.0038 | 0.0211 |
Schistosoma mansoni | UDP-glucose 4-epimerase | 0.0305 | 0.9596 | 1 |
Brugia malayi | NAD dependent epimerase/dehydratase family protein | 0.0012 | 0.0084 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0851 | 0.0886 |
Trichomonas vaginalis | dullard protein, putative | 0.0012 | 0.0084 | 0.0087 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus multilocularis | NADH dehydrogenase (ubiquinone) 1 alpha | 0.0012 | 0.0084 | 0.0088 |
Trypanosoma cruzi | hypothetical protein | 0.0012 | 0.0084 | 0.0088 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0038 | 0.004 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0012 | 0.0084 | 0.0087 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0011 | 0.0038 | 0.0211 |
Trypanosoma brucei | cytochrome P450, putative | 0.0011 | 0.0038 | 0.0038 |
Trichomonas vaginalis | NAD dependent epimerase/dehydratase, putative | 0.0012 | 0.0084 | 0.0088 |
Brugia malayi | epimerase/reductase | 0.0012 | 0.0084 | 0.0088 |
Mycobacterium ulcerans | hypothetical protein | 0.0012 | 0.0084 | 0.0467 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0087 |
Echinococcus multilocularis | Carboxy terminal domain RNA polymerase II | 0.0012 | 0.0084 | 0.0087 |
Trypanosoma cruzi | UDP-galactose 4-epimerase | 0.0305 | 0.9596 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0046 |
Leishmania major | hypothetical protein, conserved | 0.0012 | 0.0084 | 0.0046 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0011 | 0.0038 | 0.0211 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0851 | 0.0886 |
Mycobacterium leprae | conserved hypothetical protein | 0.0012 | 0.0084 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.5195 | 0.5414 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0065 | 0.1801 | 0.1877 |
Trypanosoma brucei | NAD dependent epimerase/dehydratase family, putative | 0.0012 | 0.0084 | 0.0084 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0038 | 0.004 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0011 | 0.0038 | 0.0211 |
Giardia lamblia | Nucleoside-diphosphate-sugar epimerases | 0.0012 | 0.0084 | 0.0084 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.