Detailed information for compound 182708

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 593.633 | Formula: C29H31F4N3O4S
  • H donors: 1 H acceptors: 2 LogP: 5.9 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(O/C(=C/1\C(=NC(=S)N([C@@H]1c1ccccc1C(F)(F)F)C(=O)OC1CCN(CC1)Cc1ccc(cc1)F)C)/O)C
  • InChi: 1S/C29H31F4N3O4S/c1-17(2)39-26(37)24-18(3)34-27(41)36(25(24)22-6-4-5-7-23(22)29(31,32)33)28(38)40-21-12-14-35(15-13-21)16-19-8-10-20(30)11-9-19/h4-11,17,21,25,37H,12-16H2,1-3H3/b26-24+/t25-/m1/s1
  • InChiKey: OTTAZZYTYCBVQV-NPJIAGGLSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0038 0.0038
Echinococcus multilocularis G protein coupled receptor 139 0.0045 0.0105 0.0105
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Toxoplasma gondii hypothetical protein 0.0027 0.005 0.1926
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0105 0.0313
Brugia malayi nuclear hormone receptor 0.0012 0.0009 0.0009
Echinococcus multilocularis serotonin receptor 0.0163 0.0447 0.0447
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0092 0.016
Schistosoma mansoni bromodomain containing protein 0.001 0.0002 0.0002
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0001 0.0001
Echinococcus granulosus 7TM GPCR rhodopsin 0.0045 0.0105 0.0105
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0051 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0051
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0041 0.0092 0.0272
Giardia lamblia Fructose-bisphosphate aldolase 0.0287 0.0806 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0038 0.0038
Echinococcus granulosus GTP binding nuclear protein Ran 0.0041 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0033 0.0069 0.0068
Mycobacterium ulcerans 6-phosphofructokinase 0.0124 0.0333 0.0589
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0045 0.0105 0.0104
Brugia malayi phosphofructokinase 0.0124 0.0333 0.0333
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0038 0.0038
Echinococcus multilocularis importin 5 0.0011 0.0004 0.0004
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.005 0.005
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0066 0.0164 0.0289
Schistosoma mansoni alpha glucosidase 0.0038 0.0083 0.0083
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0037 0.0111
Schistosoma mansoni hypothetical protein 0.06 0.1716 0.1716
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0006 0.0006
Echinococcus multilocularis G-protein coupled receptor, putative 0.0045 0.0105 0.0105
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0014 0.0071
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0259 0.0725 0.2193
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0045 0.0105 0.0104
Brugia malayi serine/threonine-protein kinase plk-2 0.0099 0.0262 0.0262
Brugia malayi regulator of G-protein signaling egl-10 0.0023 0.0038 0.0038
Brugia malayi hypothetical protein 0.0023 0.0038 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0037 0.0111
Loa Loa (eye worm) dihydrofolate reductase 0.0173 0.0474 0.0473
Schistosoma mansoni myosin xvIII 0.0045 0.0105 0.0104
Brugia malayi Calcitonin receptor-like protein seb-1 0.011 0.0291 0.0291
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0336 0.0947 0.0947
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0071 0.0179 0.0178
Brugia malayi Dihydrofolate reductase 0.0173 0.0474 0.0474
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0045 0.0105 0.0104
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0036 0.0077 0.0077
Loa Loa (eye worm) RNA binding protein 0.0143 0.0387 0.0386
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0083 0.0247
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0806 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0012 0.0008 0.0008
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.005 0.005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.005 0.005
Echinococcus granulosus bloom syndrome protein 0.0023 0.004 0.004
Echinococcus multilocularis lamin dm0 0.0088 0.0227 0.0227
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0083 0.3214
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0027
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis RUN 0.0022 0.0038 0.0038
Echinococcus granulosus neuropeptide receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0038 0.0038
Echinococcus multilocularis orexin receptor type 2 0.0045 0.0105 0.0105
Schistosoma mansoni opsin-like receptor 0.0045 0.0105 0.0104
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0023 0.0038 0.0038
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0074 0.0074
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.0568 0.1623 0.1622
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.005 0.005
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0079 0.0078
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.007 0.0332
Brugia malayi DNA-directed RNA polymerase, beta subunit family protein 0.0014 0.0013 0.0013
Brugia malayi hypothetical protein 0.0012 0.0009 0.0009
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Onchocerca volvulus 0.0045 0.0105 0.0615
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0071 0.0179 0.0179
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0011 0.0005 0.0014
Brugia malayi hypothetical protein 0.0022 0.0038 0.0038
Mycobacterium ulcerans glyoxalase GloA 0.0041 0.0092 0.016
Brugia malayi nuclear hormone receptor family member nhr-6 0.0012 0.0009 0.0009
Echinococcus granulosus neuroligin 0.0584 0.1667 0.1667
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0584 0.1667 0.1667
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus transportin 1 0.0011 0.0004 0.0004
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0099 0.0259 0.1252
Onchocerca volvulus Lactoylglutathione lyase homolog 0.0041 0.0092 0.0539
Loa Loa (eye worm) importin-beta domain-containing protein 0.0011 0.0004 0.0003
Schistosoma mansoni rab6-interacting 0.0022 0.0038 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0077 0.0077
Brugia malayi Cytochrome P450 family protein 0.0016 0.002 0.002
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0584 0.1667 0.1667
Schistosoma mansoni dihydrofolate reductase 0.0173 0.0474 0.0474
Loa Loa (eye worm) nuclear hormone receptor 0.0012 0.0009 0.0008
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0014 0.0013 0.0078
Echinococcus multilocularis allatostatin A receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.0104
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0244 0.2993
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Plasmodium vivax aspartyl protease, putative 0.0017 0.0022 0.0096
Plasmodium falciparum histone acetyltransferase GCN5 0.009 0.0236 0.1141
Echinococcus granulosus histone acetyltransferase KAT2B 0.0326 0.092 0.092
Loa Loa (eye worm) TAR-binding protein 0.0143 0.0387 0.0386
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0028 0.0047
Trypanosoma brucei calpain, putative 0.0259 0.0725 0.2193
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.005 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0083 0.0499
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.005 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.005 0.0049
Schistosoma mansoni acetylcholinesterase 0.0584 0.1667 0.1667
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0077 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Onchocerca volvulus 0.0045 0.0105 0.0615
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.005 0.005
Echinococcus multilocularis 6 phosphofructokinase 0.0124 0.0333 0.0333
Echinococcus granulosus g protein coupled receptor 0.0045 0.0105 0.0105
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0105 0.0105
Schistosoma mansoni zinc finger protein 0.001 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Loa Loa (eye worm) DNA-directed RNA polymerase II second largest subunit 0.0014 0.0013 0.0013
Toxoplasma gondii DNA-directed RNA polymerase I RPA2 0.001 0.0002 0.0071
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0014 0.0013 0.0157
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0718 0.2058 0.3663
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.005 0.005
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.007 0.2703
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0023 0.0038 0.0038
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0008 0.0008
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0023 0.0038 0.0228
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0333 0.1995
Schistosoma mansoni biogenic amine (5HT) receptor 0.0163 0.0447 0.0447
Schistosoma mansoni tar DNA-binding protein 0.0143 0.0387 0.0387
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0041 0.0093 0.0093
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0124 0.0333 0.3871
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Brugia malayi hypothetical protein 0.0017 0.0022 0.0022
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0014 0.0128
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Plasmodium falciparum plasmepsin IV 0.0071 0.0179 0.0867
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0034 0.0034
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0155 0.0155
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2193
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0045 0.0105 0.0105
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0584 0.1667 0.1667
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0095
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0014 0.0013 0.0013
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0034 0.0034
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0008 0.0008
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0056 0.0056
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni tar DNA-binding protein 0.0143 0.0387 0.0387
Echinococcus granulosus DNA directed RNA polymerase II subunit RPB2 0.0014 0.0013 0.0013
Brugia malayi Cytochrome P450 family protein 0.0016 0.002 0.002
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0045 0.0105 0.0105
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0265 0.0265
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.005 0.005
Mycobacterium tuberculosis Conserved protein 0.0041 0.0092 0.016
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.1926
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0051 0.0088
Schistosoma mansoni memapsin-2 (A01 family) 0.0017 0.0022 0.0022
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0008
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0024
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0014 0.0037
Brugia malayi cytoplasmic intermediate filament protein 0.0047 0.0109 0.0109
Trypanosoma brucei C-8 sterol isomerase, putative 0.1148 0.3307 1
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi Bromodomain containing protein 0.001 0.0002 0.0002
Onchocerca volvulus 0.0099 0.0261 0.1554
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Echinococcus granulosus acetylcholinesterase 0.3454 1 1
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.1943 0.5615 1
Brugia malayi excitatory GABA receptor EXP-1A 0.0012 0.0008 0.0008
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0169 0.0296
Schistosoma mansoni bromodomain containing protein 0.001 0.0002 0.0002
Loa Loa (eye worm) acetylcholinesterase 1 0.3454 1 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.005 0.005
Chlamydia trachomatis dihydrofolate reductase 0.0173 0.0474 0.2182
Echinococcus granulosus snurportin 1 0.06 0.1716 0.1716
Echinococcus granulosus allatostatin A receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Schistosoma mansoni opsin-like receptor 0.0045 0.0105 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0105 0.0104
Brugia malayi Sulfatase family protein 0.001 0.0002 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0101 0.0265 0.0264
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0045 0.0105 0.0104
Entamoeba histolytica serine/threonine protein kinase, putative 0.0099 0.0262 0.3216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0006 0.0006
Schistosoma mansoni alpha-glucosidase 0.0148 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi Bromodomain containing protein 0.0037 0.008 0.008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0009 0.0009
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0244 0.2993
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0026 0.005 0.005
Brugia malayi NC domain containing protein 0.0048 0.0112 0.0112
Brugia malayi Carboxylesterase family protein 0.3454 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Schistosoma mansoni cpg binding protein 0.0032 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0008 0.0008
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0014 0.0037
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.005 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0039 0.0039
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0074 0.0074
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0038 0.0038
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0136 0.0412
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Echinococcus granulosus hypothetical protein 0.0045 0.0105 0.0105
Brugia malayi hypothetical protein 0.0022 0.0038 0.0038
Echinococcus granulosus dro:myosuppressin receptor 0.0045 0.0105 0.0105
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0023 0.0038 0.0038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0105 0.0105
Brugia malayi intermediate filament protein 0.0088 0.0227 0.0227
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2193
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0012 0.0008 0.0008
Echinococcus multilocularis para nitrobenzyl esterase 0.0584 0.1667 0.1667
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Trypanosoma cruzi lactoylglutathione lyase-like protein, putative 0.0041 0.0092 0.0272
Echinococcus multilocularis serotonin transporter 0.0156 0.0427 0.0427
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Onchocerca volvulus 0.0012 0.0008 0.0035
Echinococcus granulosus 6 phosphofructokinase 0.0124 0.0333 0.0333
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0021
Brugia malayi nuclear receptor RXR 0.0014 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.3454 1 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.007 0.0863
Echinococcus granulosus neuropeptide FF receptor 2 0.0045 0.0105 0.0105
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0077 0.2957
Schistosoma mansoni coup transcription factor 0.0026 0.005 0.005
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.004 0.0239
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0259 0.0725 0.2188
Plasmodium vivax glyoxalase I, putative 0.0041 0.0092 0.0438
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0045 0.0105 0.0615
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus peptide allatostatin:somatostatin 0.0045 0.0105 0.0105
Plasmodium vivax amine transporter, putative 0.0027 0.005 0.0234
Toxoplasma gondii histone lysine methyltransferase SET1 0.0071 0.0178 0.6863
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0009 0.0009
Schistosoma mansoni importin-beta 2 0.0011 0.0004 0.0004
Loa Loa (eye worm) RNA polymerase III 128kD subunit-PA 0.0014 0.0013 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0023 0.0039 0.0039
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.001 0.0002 0.0002
Echinococcus multilocularis lamin 0.0088 0.0227 0.0227
Trichomonas vaginalis bromodomain-containing protein, putative 0.0099 0.0259 0.1555
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0026 0.005 0.0285
Brugia malayi RE15519p 0.0045 0.0105 0.0104
Echinococcus granulosus g-protein coupled receptor 0.0045 0.0105 0.0105
Giardia lamblia PHD finger protein 15 0.0029 0.0056 0.0687
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0262 0.0786
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0039 0.0039
Plasmodium vivax SET domain protein, putative 0.0036 0.0077 0.0364
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0163 0.0447 0.0447
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.005 0.005
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Plasmodium vivax SET domain containing protein 0.001 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0014 0.0083
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0173 0.0474 0.084
Plasmodium falciparum DNA-directed RNA polymerase I subunit RPA2, putative 0.001 0.0002 0.0006
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0066 0.0165 0.0497
Brugia malayi nuclear hormone receptor family member odr-7 0.0012 0.0009 0.0009
Echinococcus granulosus Regulator of G protein signaling 20 0.0023 0.0038 0.0038
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0082 0.0212 0.1272
Schistosoma mansoni cathepsin D (A01 family) 0.0071 0.0179 0.0179
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0008 0.0008
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0718 0.2058 1
Echinococcus multilocularis neuropeptide receptor 0.0045 0.0105 0.0105
Brugia malayi Importin beta-1 subunit 0.0056 0.0136 0.0136
Onchocerca volvulus 0.0027 0.005 0.0287
Schistosoma mansoni jun-related protein 0.0071 0.0179 0.0178
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2188
Echinococcus granulosus importin 5 0.0011 0.0004 0.0004
Onchocerca volvulus 0.0584 0.1667 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0584 0.1667 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Brugia malayi Serotonin receptor 0.1022 0.2941 0.2941
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0471 0.0471
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0037 0.0037
Schistosoma mansoni nuclear receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Trypanosoma brucei DNA-directed RNA polymerase II subunit 2, putative 0.0014 0.0013 0.004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0105 0.063
Loa Loa (eye worm) 4-hydroxyphenylpyruvate dioxygenase 0.0279 0.0784 0.0783
Plasmodium falciparum plasmepsin III 0.0017 0.0022 0.0102
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.005 0.005
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0087 0.0226 0.0226
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1778 0.5136 0.5136
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Echinococcus granulosus regulator of G protein signaling 3 0.0023 0.0038 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0079 0.0079
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0105 0.0105
Echinococcus granulosus thyroid hormone receptor alpha 0.0012 0.0009 0.0009
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0049 0.0117 0.0117
Leishmania major importin beta-1 subunit, putative 0.0046 0.0105 0.0313
Echinococcus granulosus DNA directed RNA polymerase III subunit RPC2 0.0014 0.0013 0.0013
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Onchocerca volvulus 0.0045 0.0105 0.0615
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0041 0.0091 0.009
Brugia malayi hypothetical protein 0.0584 0.1667 0.1667
Brugia malayi Pepsin A precursor 0.0017 0.0022 0.0022
Onchocerca volvulus 0.0045 0.0105 0.0615
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0105 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Brugia malayi tailless protein 0.0012 0.0009 0.0009
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0041 0.0093 0.0281
Echinococcus multilocularis BC026374 protein (S09 family) 0.0584 0.1667 0.1667
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0244 0.2993
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0099 0.0262 0.0261
Onchocerca volvulus UPF0528 protein homolog 0.0048 0.0112 0.066
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0333 0.0333
Onchocerca volvulus Protein ultraspiracle homolog 0.0026 0.005 0.0285
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus dna polymerase kappa 0.0022 0.0037 0.0037
Brugia malayi aspartic protease BmAsp-1, identical 0.0017 0.0022 0.0022
Brugia malayi hypothetical protein 0.0023 0.0038 0.0038
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1148 0.3307 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.005 0.005
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0074 0.0074
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.005 0.005
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0105 0.0104
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0008
Echinococcus multilocularis acetylcholinesterase 0.3454 1 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0099 0.0262 0.0786
Loa Loa (eye worm) hypothetical protein 0.0373 0.1055 0.1054
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2193
Loa Loa (eye worm) melatonin receptor type 1A 0.0045 0.0105 0.0104
Echinococcus multilocularis nAChR subunit 0.0012 0.0008 0.0008
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0082 0.0212 0.1029
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0718 0.2058 1
Onchocerca volvulus 0.0045 0.0105 0.0615
Giardia lamblia DNA-directed RNA polymerase RPB2 0.0014 0.0013 0.0157
Schistosoma mansoni cpg binding protein 0.0034 0.0072 0.0072
Brugia malayi Pre-SET motif family protein 0.0245 0.0685 0.0685
Echinococcus granulosus lamin 0.0088 0.0227 0.0227
Mycobacterium ulcerans carboxylesterase, LipT 0.0584 0.1667 0.2966
Brugia malayi Doublecortin family protein 0.0022 0.0038 0.0038
Onchocerca volvulus 0.0045 0.0105 0.0615
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0034 0.0098
Echinococcus multilocularis somatostatin receptor 0.0045 0.0105 0.0105
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.005 0.005
Echinococcus granulosus translational activator gcn1 0.0011 0.0004 0.0004
Echinococcus granulosus somatostatin receptor 0.0045 0.0105 0.0105
Echinococcus granulosus tm gpcr rhodopsin 0.0549 0.1566 0.1566
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0037 0.0037
Treponema pallidum NAD synthetase 0.0082 0.0212 0.2308
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0027 0.0051 0.0296
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Trypanosoma brucei NAD+ synthase, putative 0.0082 0.0212 0.0642
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0083 0.0247
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2193
Brugia malayi orphan nuclear receptor NR2E1 0.0012 0.0009 0.0009
Brugia malayi regulator of G-protein signaling rgs-7 0.0023 0.0038 0.0038
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0333 0.1006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0045 0.0105 0.0105
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0259 0.0725 0.2188
Onchocerca volvulus Neuropeptide F receptor homolog 0.0045 0.0105 0.0615
Schistosoma mansoni thyroid hormone receptor 0.0026 0.005 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.005 0.0049
Trichomonas vaginalis ran, putative 0.0041 0.0093 0.0557
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0045 0.0105 0.0104
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0014 0.0083
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0045 0.0105 0.0105
Toxoplasma gondii aspartyl protease ASP1 0.0071 0.0179 0.6903
Entamoeba histolytica hypothetical protein 0.0035 0.0076 0.0897
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0099 0.0262 0.0786
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Echinococcus multilocularis beta adrenergic receptor kinase 0.0023 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0008
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0014 0.0083
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.3454 1 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0012 0.0009 0.0009
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0027 0.005 0.005
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0056 0.0055
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0009 0.0009
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0014 0.0013 0.0119
Brugia malayi kap beta 3 protein 0.0011 0.0004 0.0004
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0038 0.0038
Echinococcus granulosus nAChR subunit 0.0012 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0083 0.0993
Echinococcus multilocularis neuropeptide FF receptor 2 0.0045 0.0105 0.0105
Leishmania major glyoxalase I,trypanothione-dependent glyoxalase I 0.0041 0.0092 0.0272
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.005 0.005
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0012 0.0008 0.0008
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0143 0.0387 0.0386
Plasmodium falciparum plasmepsin I 0.0071 0.0179 0.0867
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0037 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.005 0.0049
Trichomonas vaginalis set domain proteins, putative 0.0279 0.0783 0.4694
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.0265 0.0265
Schistosoma mansoni loxhd1 0.0022 0.0038 0.0038
Onchocerca volvulus 0.0045 0.0105 0.0615
Onchocerca volvulus 0.0012 0.0008 0.0035
Brugia malayi G protein-coupled receptor 0.0045 0.0105 0.0104
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0037 0.0111
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0026 0.005 0.005
Mycobacterium ulcerans glyoxalase GloA 0.0041 0.0092 0.016
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0051 0.0051
Echinococcus granulosus sodium and chloride dependent glycine 0.0027 0.005 0.005
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0037 0.0105
Entamoeba histolytica Ran family GTPase 0.0041 0.0093 0.1114
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0037 0.0411
Onchocerca volvulus Putative nachr subunit 0.0012 0.0008 0.0035
Brugia malayi aspartic protease BmAsp-2, identical 0.0017 0.0022 0.0022
Schistosoma mansoni DNA-directed RNA polymerase I subunit 0.001 0.0002 0.0002
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0038 0.0038
Treponema pallidum fructose-bisphosphate aldolase 0.0287 0.0806 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0099 0.0259 0.0259
Echinococcus granulosus neuropeptide s receptor 0.0045 0.0105 0.0105
Schistosoma mansoni amine GPCR 0.0045 0.0105 0.0104
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0071 0.0179 0.6903
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0034 0.0418
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0017 0.0022 0.0833
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0124 0.0333 0.3993
Echinococcus multilocularis neuropeptide receptor A26 0.0045 0.0105 0.0105
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.005
Brugia malayi putative neuropeptide receptor NPR1 0.0045 0.0105 0.0104
Echinococcus granulosus cpg binding protein 0.0034 0.0072 0.0072
Entamoeba histolytica hypothetical protein 0.0023 0.0038 0.043
Brugia malayi hypothetical protein 0.0027 0.005 0.005
Brugia malayi RNA recognition motif domain containing protein 0.0143 0.0387 0.0387
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0041 0.0093 0.0093
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Schistosoma mansoni microtubule-associated protein tau 0.0716 0.2051 0.2051
Echinococcus multilocularis nuclear receptor nhr 48 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Echinococcus multilocularis translational activator gcn1 0.0011 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.005 0.005
Echinococcus granulosus glycine receptor subunit beta 0.0012 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0063 0.0156 0.0156
Schistosoma mansoni intermediate filament proteins 0.0088 0.0227 0.0227
Entamoeba histolytica acetyltransferase, GNAT family 0.009 0.0236 0.2891
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0584 0.1667 0.1667
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.004 0.0239
Schistosoma mansoni nuclear receptor nhr-48 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0038 0.0038
Plasmodium falciparum plasmepsin VII 0.0017 0.0022 0.0102
Onchocerca volvulus 0.0584 0.1667 1
Loa Loa (eye worm) hypothetical protein 0.011 0.0291 0.0291
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0718 0.2058 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0012 0.0008 0.0008
Echinococcus granulosus jun protein 0.0087 0.0226 0.0226
Trypanosoma brucei glucosidase, putative 0.0038 0.0083 0.0252
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0105 0.0105
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0037 0.0037
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0101 0.0265 0.0265
Brugia malayi lactoylglutathione lyase 0.0041 0.0092 0.0092
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0051 0.0088
Brugia malayi Tachykinin-like peptides receptor 99D 0.0045 0.0105 0.0104
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0006 0.0005
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0012 0.0009 0.0009
Plasmodium falciparum transportin 0.0011 0.0004 0.0015
Plasmodium falciparum DNA-directed RNA polymerase III subunit RPC2, putative 0.0014 0.0013 0.0061
Brugia malayi Pre-SET motif family protein 0.0036 0.0077 0.0077
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0027 0.005 0.005
Brugia malayi nuclear hormone receptor 0.0026 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0156 0.0427 0.0426
Schistosoma mansoni cpg binding protein 0.0034 0.0072 0.0072
Schistosoma mansoni 4-hydroxyphenylpyruvate dioxygenase 0.0041 0.0092 0.0092
Toxoplasma gondii glyoxalase I, putative 0.0041 0.0092 0.3543
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0051 0.015
Plasmodium vivax DNA-directed RNA polymerase III subunit, putative 0.0014 0.0013 0.0055
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0007
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0105 0.063
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0041 0.0093 0.0092
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0067 0.0169 0.0296
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0013 0.0013
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0042 0.0096 0.0096
Schistosoma mansoni kinase 0.0051 0.012 0.012
Schistosoma mansoni GMP synthetase 0.0033 0.0069 0.0069
Toxoplasma gondii DNA-directed RNA polymerase II RPB2 0.0014 0.0013 0.0511
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0094 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0574 0.1639 0.1639
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0012 0.0008 0.0035
Plasmodium vivax DNA-directed RNA polymerase II subunit RPB2, putative 0.0014 0.0013 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0085 0.0219 0.0218
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0045 0.0105 0.0105
Onchocerca volvulus 0.0045 0.0105 0.0615
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0038 0.0038
Echinococcus multilocularis DNA directed RNA polymerase III subunit RPC2 0.0014 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.005 0.005
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.005 0.005
Loa Loa (eye worm) RGS-3 protein 0.0023 0.0038 0.0038
Echinococcus granulosus lysine specific demethylase 5A 0.0036 0.0079 0.0079
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0056 0.0056
Echinococcus multilocularis regulator of G protein signaling 0.0023 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Echinococcus multilocularis expressed protein 0.0438 0.1246 0.1246
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0031
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0045 0.0105 0.0105
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Echinococcus granulosus sex peptide receptor 0.0045 0.0105 0.0105
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0012 0.0008 0.0008
Plasmodium vivax hypothetical protein, conserved 0.0027 0.005 0.0234
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0037 0.0062
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.007 0.2703
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0012 0.0008 0.0007
Entamoeba histolytica hypothetical protein 0.0023 0.0038 0.043
Brugia malayi Intermediate filament tail domain containing protein 0.0088 0.0227 0.0227
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0086 0.0222 0.0222
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0051 0.0594
Schistosoma mansoni hypothetical protein 0.0075 0.0191 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Schistosoma mansoni ran 0.0041 0.0093 0.0093
Schistosoma mansoni growth hormone secretagogue receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis serotonin receptor 0.0163 0.0447 0.0447
Onchocerca volvulus Serine\/threonine kinase homolog 0.0099 0.0262 0.1558
Schistosoma mansoni biogenic amine receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0088 0.0227 0.0226
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0014 0.0013 0.0119
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0034 0.0098
Onchocerca volvulus 0.0045 0.0105 0.0615
Onchocerca volvulus 0.0068 0.0172 0.1017
Loa Loa (eye worm) hypothetical protein 0.0056 0.0136 0.0136
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0074 0.0074
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0012 0.0008 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0163 0.0447 0.0447
Brugia malayi ecdysteroid receptor 0.0026 0.005 0.005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0584 0.1667 0.1667
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0333 0.1995
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.005 0.005
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.06 0.1716 0.1715
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0083 0.0083
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0014 0.0083
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0032 0.0152
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0014 0.0083
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.007 0.0338
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0156 0.0156
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0077 0.0077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0088 0.0227 0.0226
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0013 0.0013
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.014 0.038 0.0672
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0083 0.0499
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0083 0.0499
Loa Loa (eye worm) hypothetical protein 0.0035 0.0074 0.0073
Schistosoma mansoni amine GPCR 0.0045 0.0105 0.0104
Schistosoma mansoni biogenic amine receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis glycine receptor subunit beta 0.0012 0.0008 0.0008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.005 0.005
Brugia malayi hypothetical protein 0.001 0.0002 0.0002
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0077 0.0076
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0067 0.0169 0.0296
Schistosoma mansoni tar DNA-binding protein 0.0143 0.0387 0.0387
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0076 0.0076
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.002 0.0019
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.007 0.019
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.1943 0.5615 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0013
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0038 0.0038
Mycobacterium ulcerans GMP synthase 0.0033 0.0069 0.0118
Brugia malayi Carboxylesterase family protein 0.0584 0.1667 0.1667
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0083 0.0499
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0045 0.0105 0.0105
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0004 0.0144
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) RecQ helicase 0.0023 0.004 0.0039
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0083 0.0499
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Echinococcus granulosus Nuclear hormone receptor HR96 0.0012 0.0009 0.0009
Echinococcus multilocularis snurportin 1 0.06 0.1716 0.1716
Mycobacterium ulcerans NAD synthetase 0.0082 0.0212 0.0374
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0017 0.0051
Schistosoma mansoni BC026374 protein (S09 family) 0.0584 0.1667 0.1667
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.014 0.038 0.0672
Entamoeba histolytica hypothetical protein 0.0035 0.0076 0.0897
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0259 0.0725 0.2193
Trypanosoma brucei unspecified product 0.0015 0.0017 0.0051
Brugia malayi 4-hydroxyphenylpyruvate dioxygenase family protein 0.0279 0.0784 0.0784
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2193
Brugia malayi Serotonin receptor 0.0045 0.0105 0.0104
Brugia malayi G protein-coupled receptor F59B2.13 0.0045 0.0105 0.0104
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0105 0.0104
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.007 0.2703
Echinococcus granulosus serotonin receptor 0.0045 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.094 0.2702 0.2702
Schistosoma mansoni lamin 0.0088 0.0227 0.0227
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0105 0.0105
Brugia malayi sulfakinin receptor protein 0.0045 0.0105 0.0104
Echinococcus granulosus microtubule associated protein 2 0.0716 0.2051 0.2051
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Schistosoma mansoni amine GPCR 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.005 0.005
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0037 0.0219
Schistosoma mansoni sodium/chloride dependent transporter 0.0027 0.0051 0.0051
Echinococcus granulosus peregrin 0.0037 0.008 0.008
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0027 0.005 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0008 0.0007
Echinococcus multilocularis neuropeptide s receptor 0.0045 0.0105 0.0105
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.005 0.005
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0033 0.0069 0.2644
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0051 0.0594
Loa Loa (eye worm) ACC-1 protein 0.0012 0.0008 0.0007
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0034 0.0204
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0045 0.0105 0.0104
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0101 0.0265 0.0265
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0008
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0023 0.0038 0.0038
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0083 0.0499
Schistosoma mansoni alpha-glucosidase 0.0148 0.0402 0.0402
Toxoplasma gondii exonuclease III APE 0.0021 0.0034 0.1319
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0012 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0023 0.0038 0.043
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0014 0.0014
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0009 0.0009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.011 0.0291 0.0291
Onchocerca volvulus 0.0017 0.0022 0.0117
Leishmania major C-8 sterol isomerase-like protein 0.1148 0.3307 1
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.005 0.005
Loa Loa (eye worm) serotonin transporter b 0.0156 0.0427 0.0426
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0259 0.0725 0.2188
Echinococcus multilocularis peregrin 0.0037 0.008 0.008
Brugia malayi larval opioid receptor 0.0045 0.0105 0.0104
Schistosoma mansoni hypothetical protein 0.0022 0.0038 0.0038
Echinococcus multilocularis dihydrofolate reductase 0.0173 0.0474 0.0474
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0004 0.0144
Onchocerca volvulus 0.0045 0.0105 0.0615
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Onchocerca volvulus 0.0045 0.0105 0.0615
Echinococcus multilocularis musashi 0.0088 0.0227 0.0227
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0013 0.0013
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0156 0.0427 0.0427
Echinococcus granulosus g protein coupled receptor 0.0045 0.0105 0.0105
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0041 0.0093 0.1148
Echinococcus granulosus tm gpcr rhodopsin 0.0045 0.0105 0.0105
Brugia malayi TAR-binding protein 0.0143 0.0387 0.0387
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0083 0.0499
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus 7tm_1 domain containing protein 0.0045 0.0105 0.0105
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Brugia malayi DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide 0.0014 0.0013 0.0013
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0012 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0027 0.0051 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.005 0.005
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0017 0.0051
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0089 0.0089
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0105 0.0105
Schistosoma mansoni neuroligin 3 (S09 family) 0.0584 0.1667 0.1667
Brugia malayi Carboxylesterase family protein 0.0584 0.1667 0.1667
Schistosoma mansoni rab6-interacting 0.0022 0.0038 0.0038
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.007 0.0338
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0045 0.0105 0.0105
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0051 0.015
Echinococcus granulosus para nitrobenzyl esterase 0.0584 0.1667 0.1667
Schistosoma mansoni thyroid hormone receptor 0.0026 0.005 0.005
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0051 0.0088
Loa Loa (eye worm) hypothetical protein 0.1148 0.3307 0.3306
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Echinococcus multilocularis dnaJ subfamily B 0.094 0.2702 0.2702
Brugia malayi Eukaryotic aspartyl protease family protein 0.0017 0.0022 0.0022
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0071 0.0179 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.005 0.005
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.027 0.0756 0.1343
Loa Loa (eye worm) hypothetical protein 0.0296 0.0833 0.0832
Leishmania major hypothetical protein, conserved 0.0011 0.0004 0.0006
Schistosoma mansoni tar DNA-binding protein 0.0143 0.0387 0.0387
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.001 0.0002 0.0002
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0244 0.2993
Brugia malayi acetyltransferase, GNAT family protein 0.0336 0.0947 0.0947
Brugia malayi Regulator of G protein signaling domain containing protein 0.0023 0.0038 0.0038
Giardia lamblia Histone acetyltransferase GCN5 0.009 0.0236 0.2918
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Schistosoma mansoni adenoreceptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0156 0.0427 0.0426
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0009 0.0009
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0041 0.0093 0.3586
Schistosoma mansoni biogenic amine (5HT) receptor 0.0045 0.0105 0.0104
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0175 0.0175
Brugia malayi PXA domain containing protein 0.0023 0.0038 0.0038
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0169 0.0169
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0071 0.0179 0.0179
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0051 0.0051
Brugia malayi Carboxylesterase family protein 0.0584 0.1667 0.1667
Brugia malayi neuropeptide F receptor 0.0045 0.0105 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0066 0.0165 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.005 0.005
Onchocerca volvulus 0.0045 0.0105 0.0615
Trypanosoma brucei calpain-like protein, putative 0.0259 0.0725 0.2193
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0051 0.015
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0051 0.0088
Onchocerca volvulus 0.0584 0.1667 1
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0002
Schistosoma mansoni biogenic amine receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0032 0.0052
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.0026 0.005 0.0285
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0012 0.0009 0.0009
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0023 0.0038 0.0038
Schistosoma mansoni zinc finger protein 0.0012 0.0009 0.0009
Onchocerca volvulus 0.0012 0.0008 0.0035
Brugia malayi RNA, U transporter 1 0.016 0.0437 0.0437
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0056 0.2156
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.0055
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.005 0.005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0034 0.0103
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.005 0.005
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0045 0.0105 0.0105
Onchocerca volvulus 0.0012 0.0008 0.0035
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0034 0.0157
Onchocerca volvulus 0.0032 0.0067 0.0387
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0038 0.0038
Brugia malayi RNA binding protein 0.0143 0.0387 0.0387
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0038 0.0038
Mycobacterium tuberculosis Cadmium inducible protein CadI 0.0041 0.0092 0.016
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0071 0.0179 0.1073
Schistosoma mansoni hypothetical protein 0.0035 0.0076 0.0076
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Onchocerca volvulus 0.0027 0.005 0.0287
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0014 0.0083
Plasmodium vivax aspartyl proteinase, putative 0.0071 0.0179 0.0862
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0156 0.0427 0.0426
Loa Loa (eye worm) carboxylesterase 0.3454 1 1
Trypanosoma brucei DNA-directed RNA polymerase III, putative 0.0014 0.0013 0.004
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0045 0.0105 0.0104
Entamoeba histolytica hypothetical protein 0.0035 0.0076 0.0897
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0008
Schistosoma mansoni 6-phosphofructokinase 0.0124 0.0333 0.0333
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0051 0.0088
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus G protein coupled receptor 139 0.0045 0.0105 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Brugia malayi small heat shock protein 0.0608 0.1738 0.1738
Loa Loa (eye worm) neuropeptide F receptor 0.0045 0.0105 0.0104
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0012 0.0008 0.0008
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0067 0.0169 0.0168
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.001 0.0002 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0037 0.0062
Brugia malayi PHD-finger family protein 0.0011 0.0005 0.0005
Schistosoma mansoni sodium-dependent amino acid transporter 0.0027 0.005 0.005
Brugia malayi nuclear receptor NHR-67 0.0012 0.0009 0.0009
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0014 0.0013 0.0078
Brugia malayi Carboxylesterase family protein 0.0584 0.1667 0.1667
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.001 0.0002 0.0001
Toxoplasma gondii hypothetical protein 0.0048 0.0112 0.4319
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0045 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Giardia lamblia DNA-directed RNA polymerase subunit B 0.001 0.0002 0.0015
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0027 0.005 0.005
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0033 0.0069 0.033
Mycobacterium tuberculosis Conserved protein 0.0041 0.0092 0.016
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0041 0.0093 0.0443
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0718 0.2058 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0012 0.0009 0.0008
Mycobacterium ulcerans biphenyl-2,3-diol 1,2-dioxygenase 0.0041 0.0092 0.016
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0012 0.0008 0.0008
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus orexin receptor type 2 0.0045 0.0105 0.0105
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0023 0.0039 0.0039
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0027 0.005 0.005
Loa Loa (eye worm) carboxylesterase 0.0584 0.1667 0.1667
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni hypothetical protein 0.0568 0.1623 0.1622
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0012 0.0008 0.0008
Schistosoma mansoni nuclear receptor 0.0012 0.0009 0.0009
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0082 0.0212 0.2283
Loa Loa (eye worm) hypothetical protein 0.0071 0.0179 0.0178
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0035 0.0076 0.0897
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0028 0.0047
Schistosoma mansoni lamin 0.0088 0.0227 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Loa Loa (eye worm) hypothetical protein 0.0048 0.0112 0.0111
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0012 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0587 0.1677 0.1676
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0037 0.0036
Echinococcus granulosus dnaJ subfamily B 0.094 0.2702 0.2702
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0009 0.0063
Brugia malayi Cation transporter family protein 0.0012 0.0008 0.0008
Echinococcus granulosus RUN 0.0022 0.0038 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0075 0.0191 0.019
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.005 0.005
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0012 0.0008 0.0007
Plasmodium falciparum transporter, putative 0.0027 0.005 0.024
Onchocerca volvulus 0.0012 0.0009 0.0042
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0608 0.1738 0.1738
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0105 0.0105
Onchocerca volvulus 0.0022 0.0038 0.0216
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.007 0.0332
Plasmodium falciparum amino acid transporter, putative 0.0027 0.005 0.024
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.005 0.005
Echinococcus multilocularis GPCR, family 2 0.0035 0.0074 0.0074
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.005 0.0049
Echinococcus multilocularis carboxylesterase 5A 0.3454 1 1
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0083 0.0499
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.005 0.005
Loa Loa (eye worm) acetyltransferase 0.0336 0.0947 0.0946
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.3454 1 1
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0333 0.4104
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0014 0.0083
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.0471 0.047
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.002 0.0032
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0045 0.0105 0.0104
Loa Loa (eye worm) DR-78 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0051 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0031
Entamoeba histolytica NAD synthetase, putative 0.0082 0.0212 0.2601
Loa Loa (eye worm) aspartyl protease 6 0.0017 0.0022 0.0021
Plasmodium falciparum plasmepsin VI 0.0071 0.0179 0.0867
Onchocerca volvulus 0.0045 0.0105 0.0615
Brugia malayi hypothetical protein 0.0068 0.0172 0.0171
Giardia lamblia Kinase, PLK 0.0099 0.0262 0.3242
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0333 0.4104
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0099 0.0259 0.1555
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.1926
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Leishmania major DNA-directed RNA polymerase polypeptide, putative 0.0014 0.0013 0.0034
Giardia lamblia Hypothetical protein 0.001 0.0002 0.0019
Echinococcus granulosus importin subunit beta 1 0.0056 0.0136 0.0136
Loa Loa (eye worm) intermediate filament protein 0.0088 0.0227 0.0226
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0001
Plasmodium falciparum plasmepsin V 0.0017 0.0022 0.0102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Echinococcus multilocularis transportin 1 0.0011 0.0004 0.0004
Loa Loa (eye worm) CYP4Cod1 0.0016 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0584 0.1667 0.2966
Schistosoma mansoni histamine h1 receptor 0.0045 0.0105 0.0104
Leishmania major DNA polymerase eta, putative 0.0022 0.0037 0.0105
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0027 0.005 0.005
Brugia malayi AKH receptor 0.0045 0.0105 0.0104
Schistosoma mansoni hypothetical protein 0.0029 0.0056 0.0056
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Plasmodium falciparum glyoxalase I 0.0041 0.0092 0.0444
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Echinococcus granulosus acetylcholinesterase 0.3454 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0092 0.055
Schistosoma mansoni importin beta-1 0.0056 0.0136 0.0136
Schistosoma mansoni serine/threonine protein kinase 0.0023 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Brugia malayi 6-phosphofructokinase 0.0124 0.0333 0.0333
Brugia malayi 6-phosphofructokinase 0.0124 0.0333 0.0333
Plasmodium falciparum plasmepsin II 0.0071 0.0179 0.0867
Echinococcus multilocularis neuropeptide Y receptor 0.0045 0.0105 0.0105
Echinococcus multilocularis dna polymerase eta 0.0022 0.0037 0.0037
Echinococcus granulosus tachykinin peptides receptor 99D 0.0045 0.0105 0.0105
Echinococcus multilocularis neuroligin 0.0584 0.1667 0.1667
Schistosoma mansoni ran 0.0041 0.0093 0.0093
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0013 0.0013
Onchocerca volvulus Putative protein 0.0279 0.0784 0.4694
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0082 0.0212 0.0374
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.0471 0.0471
Echinococcus multilocularis tar DNA binding protein 0.0143 0.0387 0.0387
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0471 0.0471
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0074 0.0073
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0071 0.0071
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0012 0.0008 0.0008
Plasmodium vivax plasmepsin V, putative 0.0017 0.0022 0.0096
Onchocerca volvulus 0.0012 0.0008 0.0035
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.005 0.005
Schistosoma mansoni neuropeptide f receptor 76f 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0036 0.0077 0.0448
Giardia lamblia DINP protein human, muc B family 0.0022 0.0037 0.0448
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.005 0.005
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0047 0.0109 0.0108
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0045 0.0105 0.0105
Loa Loa (eye worm) kap beta 3 protein 0.0011 0.0004 0.0003
Onchocerca volvulus 0.0012 0.0009 0.0041
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0718 0.2058 0.3663
Loa Loa (eye worm) TYRA-2 protein 0.0045 0.0105 0.0104
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0012 0.0008 0.0008
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.004 0.004
Echinococcus granulosus regulator of G protein signaling 7 0.0023 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Brugia malayi Dopamine receptor protein 2 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0022 0.0038 0.0216
Brugia malayi Melatonin receptor type 1A 0.0045 0.0105 0.0104
Brugia malayi putative neuropeptide receptor 0.0045 0.0105 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Brugia malayi hypothetical protein 0.0014 0.0013 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0189 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0083 0.0247
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0012 0.0008 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0074 0.0074
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0037 0.0037
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0101 0.0265 0.0265
Schistosoma mansoni neuropeptide receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0099 0.0262 0.0262
Echinococcus granulosus geminin 0.0568 0.1623 0.1623
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0092 0.055
Echinococcus granulosus neuropeptide receptor A26 0.0045 0.0105 0.0105
Schistosoma mansoni ap endonuclease 0.0021 0.0034 0.0034
Echinococcus granulosus alpha 1A adrenergic receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0163 0.0447 0.0447
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0056 0.2156
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0051 0.0051
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0042 0.0096 0.0096
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0105 0.063
Echinococcus granulosus neuropeptides capa receptor 0.0045 0.0105 0.0105
Brugia malayi hypothetical protein 0.0012 0.0009 0.0009
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0038 0.0038
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0287 0.0806 0.4831
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0549 0.1566 0.1566
Schistosoma mansoni hypothetical protein 0.0035 0.0074 0.0074
Schistosoma mansoni opsin-like receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) norepinephrine transporter 0.0156 0.0427 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Schistosoma mansoni lipoxygenase 0.0022 0.0038 0.0038
Plasmodium vivax GMP synthetase, putative 0.0033 0.0069 0.0324
Echinococcus multilocularis acetylcholinesterase 0.3454 1 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0014 0.0083
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Plasmodium falciparum DNA-directed RNA polymerase II subunit RPB2, putative 0.0014 0.0013 0.0061
Brugia malayi PHD-finger family protein 0.001 0.0002 0.0002
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0009 0.0052
Schistosoma mansoni DNA polymerase eta 0.0022 0.0037 0.0037
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0259 0.0725 0.2188
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0034 0.0098
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus serotonin transporter 0.0156 0.0427 0.0427
Schistosoma mansoni gynecophoral canal protein 0.0041 0.0092 0.0092
Echinococcus multilocularis cpg binding protein 0.0034 0.0072 0.0072
Loa Loa (eye worm) hypothetical protein 0.0022 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0031
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0009 0.0041
Onchocerca volvulus 0.0088 0.0227 0.1351
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0012 0.0009 0.0009
Toxoplasma gondii hypothetical protein 0.0027 0.005 0.1926
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0012 0.0008 0.0008
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0718 0.2058 0.3663
Brugia malayi DNA-directed RNA polymerase II second largest subunit, putative 0.0014 0.0013 0.0013
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.007 0.019
Brugia malayi G-protein coupled receptor 0.0045 0.0105 0.0104
Onchocerca volvulus Alhambra homolog 0.0029 0.0056 0.0323
Brugia malayi follicle stimulating hormone receptor 0.0574 0.1639 0.1639
Loa Loa (eye worm) G-protein coupled receptor 0.0045 0.0105 0.0104
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0001 0.0001
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0173 0.0474 0.084
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1148 0.3307 0.3307
Onchocerca volvulus 0.0017 0.0022 0.0117
Brugia malayi GMP synthase 0.0033 0.0069 0.0069
Onchocerca volvulus 0.0279 0.0783 0.4688
Brugia malayi hypothetical protein 0.0014 0.0013 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0143 0.0387 0.0387
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Entamoeba histolytica DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide, putative 0.0014 0.0013 0.0119
Entamoeba histolytica fatty acid elongase, putative 0.0093 0.0244 0.2993
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0017 0.0051
Schistosoma mansoni cathepsin D (A01 family) 0.0071 0.0179 0.0179
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.005 0.005
Brugia malayi bZIP transcription factor family protein 0.0087 0.0226 0.0226
Onchocerca volvulus 0.0156 0.0427 0.2552
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0099 0.0262 0.0262
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0156 0.0156
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0076 0.0076
Schistosoma mansoni hypothetical protein 0.0035 0.0074 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Mycobacterium tuberculosis Conserved protein TB27.3 0.0041 0.0092 0.016
Trypanosoma brucei hypothetical protein 0.0259 0.0725 0.2193
Echinococcus granulosus intermediate filament protein 0.0088 0.0227 0.0227
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Schistosoma mansoni z-protein (S1r protein) 0.0023 0.0038 0.0038
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0116 0.0694
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.005 0.0049
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0038 0.0038
Loa Loa (eye worm) DNA-directed RNA polymerase 0.0011 0.0006 0.0005
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0045 0.0105 0.0104
Echinococcus granulosus dna polymerase eta 0.0022 0.0037 0.0037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0076 0.0076
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.005
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Echinococcus multilocularis sex peptide receptor 0.0045 0.0105 0.0105
Onchocerca volvulus 0.0584 0.1667 1
Brugia malayi conserved hypotetical protein 0.0012 0.0009 0.0009
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0099 0.0259 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0265 0.0265
Plasmodium vivax plasmepsin IV, putative 0.0071 0.0179 0.0862
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.007 0.0419
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0034 0.0057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0087 0.0226 0.0226
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0057 0.0056
Brugia malayi nuclear receptor NHR-88 0.0026 0.005 0.005
Loa Loa (eye worm) nuclear receptor NHR-67 0.0012 0.0009 0.0008
Leishmania major GTP-binding protein, putative 0.0041 0.0093 0.0276
Echinococcus granulosus g protein coupled receptor 0.0045 0.0105 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0333 0.1995
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0028 0.0047
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0041 0.0093 0.0449
Schistosoma mansoni hypothetical protein 0.0071 0.0179 0.0178
Plasmodium falciparum plasmepsin VIII, putative 0.0017 0.0022 0.0102
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis neuropeptides capa receptor 0.0045 0.0105 0.0105
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0156 0.0427 0.0427
Loa Loa (eye worm) carboxylesterase 0.0584 0.1667 0.1667
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0012 0.0008 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0116 0.0694
Echinococcus multilocularis DNA directed RNA polymerase II subunit RPB2 0.0014 0.0013 0.0013
Brugia malayi PXA domain containing protein 0.0023 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Toxoplasma gondii aspartyl protease ASP3 0.0017 0.0022 0.0833
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0027 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0041 0.0092 0.0091
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0034 0.0034
Echinococcus multilocularis g-protein coupled receptor 0.0045 0.0105 0.0105
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0023 0.0039 0.0039
Echinococcus granulosus lamin dm0 0.0088 0.0227 0.0227
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0287 0.0806 1
Giardia lamblia Hypothetical protein 0.001 0.0002 0.0019
Giardia lamblia NH3-dependent NAD+ synthetase 0.0082 0.0212 0.263
Echinococcus granulosus expressed protein 0.0438 0.1246 0.1246
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0045 0.0105 0.0105
Plasmodium falciparum glyoxalase I 0.0041 0.0092 0.0444
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0032 0.015
Brugia malayi Dopamine receptor protein 1 0.0045 0.0105 0.0104
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0092 0.0575
Loa Loa (eye worm) solute carrier family 6 member 4 0.0156 0.0427 0.0426
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0051 0.0594
Brugia malayi PHD-finger family protein 0.0029 0.0056 0.0056
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0001 0.0024
Onchocerca volvulus 0.0045 0.0105 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Brugia malayi hypothetical protein 0.0035 0.0076 0.0076
Schistosoma mansoni DNA helicase recq5 0.001 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0101 0.0265 0.0265
Echinococcus granulosus biogenic amine 5HT receptor 0.0045 0.0105 0.0105
Plasmodium falciparum importin beta, putative 0.0056 0.0136 0.0658
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0066 0.0165 0.634
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0012 0.0008 0.0008
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0037 0.0219
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0037 0.0105
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Onchocerca volvulus 0.0045 0.0105 0.0615
Echinococcus granulosus nuclear receptor nhr 48 0.0012 0.0009 0.0009
Schistosoma mansoni gliotactin 0.0584 0.1667 0.1667
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0037 0.0111
Loa Loa (eye worm) hypothetical protein 0.0026 0.005 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0077 0.0077
Loa Loa (eye worm) PXA domain-containing protein 0.0023 0.0038 0.0038
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0046 0.0105 0.1266
Plasmodium falciparum plasmepsin X 0.0017 0.0022 0.0102
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.1926
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0017 0.0022 0.0021
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0144 0.0144
Echinococcus granulosus beta-adrenergic receptor kinase 0.0023 0.0039 0.0039
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.0104
Plasmodium falciparum phd finger protein, putative 0.0029 0.0056 0.0269
Trichomonas vaginalis hypothetical protein 0.0011 0.0004 0.0021
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0031
Schistosoma mansoni amine GPCR 0.0045 0.0105 0.0104
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0038 0.0038
Plasmodium vivax aspartyl proteinase, putative 0.0017 0.0022 0.0096
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.007 0.0419
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Plasmodium vivax aspartyl protease, putative 0.0017 0.0022 0.0096
Leishmania major cytochrome p450-like protein 0.0016 0.002 0.0054
Trichomonas vaginalis DNA-directed RNA polymerase III subunit, putative 0.0014 0.0013 0.0078
Loa Loa (eye worm) hypothetical protein 0.0027 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0038 0.0038
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0045 0.0105 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Trypanosoma brucei unspecified product 0.0015 0.0017 0.0051
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.005 0.005
Echinococcus multilocularis dro:myosuppressin receptor 0.0045 0.0105 0.0105
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0033 0.0069 0.0069
Onchocerca volvulus 0.0027 0.005 0.0287
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0034 0.0163
Echinococcus multilocularis microtubule associated protein 2 0.0716 0.2051 0.2051
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0124 0.0333 0.0589
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0034 0.0034
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0027 0.005 0.005
Brugia malayi Dopamine receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) LGC-31 protein 0.0012 0.0008 0.0007
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0045 0.0105 0.0104
Leishmania major NAD synthase, putative 0.0082 0.0212 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0093 0.0276
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.027 0.0756 0.3575
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0045 0.0105 0.0615
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0006 0.0025
Trypanosoma cruzi DNA-directed RNA polymerase III, putative 0.0014 0.0013 0.0034
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0333 0.0332
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus jumonji domain containing protein 0.004 0.0089 0.0089
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0262 0.1568
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0012 0.0008 0.0008
Brugia malayi nuclear receptor RXR 0.0012 0.0009 0.0009
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0083 0.0993
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0066 0.0165 0.0492
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0067 0.0169 0.0168
Echinococcus granulosus axis inhibition protein axin 0.0023 0.0038 0.0038
Trypanosoma cruzi NAD+ synthase, putative 0.0082 0.0212 0.0637
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0105 0.0105
Brugia malayi G-protein coupled receptor 0.0045 0.0105 0.0104
Echinococcus multilocularis sodium and chloride dependent glycine 0.0027 0.005 0.005
Plasmodium vivax glyoxalase I, putative 0.0041 0.0092 0.0438
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0082 0.0212 0.0212
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.005 0.0049
Trypanosoma brucei cytochrome P450, putative 0.0016 0.002 0.006
Echinococcus multilocularis DNA directed RNA polymerase I subunit RPA2 0.0014 0.0013 0.0013
Mycobacterium ulcerans hypothetical protein 0.0041 0.0092 0.016
Plasmodium vivax aspartyl protease, putative 0.0017 0.0022 0.0096
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.005 0.005
Brugia malayi hypothetical protein 0.0143 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus histone lysine methyltransferase setb 0.0036 0.0077 0.0077
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0014 0.0037
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.007 0.0828
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0012 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0262 0.0262
Schistosoma mansoni ap endonuclease 0.0021 0.0034 0.0034
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0028 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis geminin 0.0568 0.1623 0.1623
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0012 0.0009 0.0009
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0012 0.0008 0.0008
Echinococcus granulosus tar DNA binding protein 0.0143 0.0387 0.0387
Echinococcus multilocularis regulator of G protein signaling 3 0.0023 0.0038 0.0038
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0033 0.0069 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2188
Schistosoma mansoni polycystin 1-related 0.0022 0.0038 0.0038
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0191 0.0191
Schistosoma mansoni neuropeptide receptor 0.0045 0.0105 0.0104
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0584 0.1667 0.2966
Brugia malayi neuropeptide F receptor 0.0045 0.0105 0.0104
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0032 0.0144
Echinococcus granulosus carboxylesterase 5A 0.3454 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0245 0.0685 0.0684
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0082 0.0212 0.1023
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0037 0.0111
Loa Loa (eye worm) hypothetical protein 0.0049 0.0115 0.0115
Leishmania major DNA polymerase kappa, putative 0.0022 0.0037 0.0105
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0038 0.0182
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0045 0.0105 0.0104
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0037 0.0062
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0045 0.0105 0.0105
Schistosoma mansoni regulator of G protein signaling 0.0023 0.0038 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0012 0.0008 0.0008
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0033 0.0069 0.0069
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.005 0.005
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0011 0.0004 0.0011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0051 0.0088
Brugia malayi hypothetical protein 0.0017 0.0022 0.0022
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0033 0.0069 0.0207
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.014 0.038 0.4657
Echinococcus multilocularis jun protein 0.0087 0.0226 0.0226
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.0104
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0067 0.0169 0.0504
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0013 0.0013
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0083 0.0083
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.027 0.0756 1
Schistosoma mansoni neuropeptide receptor 0.0045 0.0105 0.0104
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0014 0.0013 0.0013
Toxoplasma gondii glyoxalase family protein 0.0041 0.0092 0.3543
Brugia malayi nuclear receptor NHR-88 0.0012 0.0009 0.0009
Echinococcus granulosus GPCR family 2 0.0035 0.0074 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Schistosoma mansoni hypothetical protein 0.0035 0.0074 0.0074
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0718 0.2058 0.3663
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Brugia malayi Cytochrome P450 family protein 0.0029 0.0057 0.0057
Trypanosoma brucei importin beta-1 subunit, putative 0.0056 0.0136 0.0412
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0074 0.0074
Echinococcus multilocularis zinc finger protein 0.001 0.0002 0.0002
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0006 0.0019
Trypanosoma brucei polo-like protein kinase 0.0099 0.0262 0.0791
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0034 0.038
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0051 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.005 0.005
Toxoplasma gondii DNA-directed RNA polymerase III RPC2 0.0014 0.0013 0.0511
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0013 0.0013
Echinococcus granulosus glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0022 0.0021
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0012 0.0008 0.0008
Echinococcus granulosus BC026374 protein S09 family 0.0584 0.1667 0.1667
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0082 0.0212 0.8184
Schistosoma mansoni jumonji/arid domain-containing protein 0.0036 0.0079 0.0079
Trichomonas vaginalis phosphofructokinase, putative 0.0124 0.0333 0.1995
Trypanosoma brucei unspecified product 0.0022 0.0037 0.0111
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0012 0.0009 0.0041
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.007 0.0465
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0259 0.0725 0.2188
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0094 0.0245 0.0245
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0045 0.0105 0.0104
Echinococcus granulosus DNA directed RNA polymerase I subunit RPA2 0.0014 0.0013 0.0013
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0045 0.0105 0.0105
Brugia malayi CXXC zinc finger family protein 0.0032 0.0067 0.0067
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0012 0.0008 0.0008
Schistosoma mansoni sodium/chloride dependent transporter 0.0156 0.0427 0.0427
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0259 0.0725 0.2188
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0045 0.0105 0.0104
Echinococcus granulosus fmrfamide receptor 0.0045 0.0105 0.0105
Leishmania major ATP-dependent phosphofructokinase 0.0124 0.0333 0.1001
Echinococcus granulosus zinc finger protein 0.001 0.0002 0.0002
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0045 0.0105 0.0105
Schistosoma mansoni alpha-1 adrenergic receptor 0.0045 0.0105 0.0104
Toxoplasma gondii HEAT repeat-containing protein 0.0056 0.0136 0.5248
Echinococcus multilocularis fmrfamide receptor 0.0045 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0038 0.0228
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0045 0.0105 0.0105
Echinococcus multilocularis importin subunit beta 1 0.0056 0.0136 0.0136
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0056 0.0263
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Mycobacterium tuberculosis Carboxylesterase LipT 0.0584 0.1667 0.2966
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi A-kinase anchor protein 10, precursor 0.0023 0.0038 0.0038
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0022 0.0037 0.0036
Treponema pallidum sodium- and chloride- dependent transporter 0.0156 0.0427 0.5093
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Echinococcus multilocularis g protein coupled receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Schistosoma mansoni DNA helicase recq1 0.001 0.0001 0.0001
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0045 0.0105 0.0104
Brugia malayi hypothetical protein 0.0045 0.0105 0.0104
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0037 0.0037
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0336 0.0947 0.0947
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Brugia malayi dihydrofolate reductase family protein 0.0173 0.0474 0.0474
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0021
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0066 0.0165 0.0791
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0584 0.1667 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0091 0.009
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0124 0.0333 0.1001
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.005 0.005
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0038 0.0176
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.002 0.0054
Brugia malayi ORL1-like opioid receptor 0.0045 0.0105 0.0104
Echinococcus granulosus neuropeptide receptor 0.0045 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0012 0.0008 0.0008
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0027 0.005 0.005
Plasmodium vivax transportin, putative 0.0011 0.0004 0.0009
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0083 0.0499
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0031
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0173 0.0474 0.5995
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0012 0.0008 0.0008
Onchocerca volvulus 0.0026 0.005 0.0285
Trypanosoma cruzi NAD+ synthase, putative 0.0082 0.0212 0.0637
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0034 0.0057
Loa Loa (eye worm) phosphofructokinase 0.0124 0.0333 0.0332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0032 0.0052
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0037 0.0105
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0008
Brugia malayi Nuclear hormone receptor E75 0.0012 0.0009 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0124 0.0333 0.4104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0012 0.0008 0.0008
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0012 0.0008 0.0008
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0034 0.0204
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0045 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0105 0.0104
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0014 0.0042
Echinococcus granulosus FTZ F1 alpha 0.0026 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0038 0.0038
Schistosoma mansoni axis inhibition protein axin 0.0023 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.005 0.005
Schistosoma mansoni DNA-directed rna polymerase II subunit 0.0014 0.0013 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0027 0.0027
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Echinococcus multilocularis bloom syndrome protein 0.0023 0.004 0.004
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.027 0.0756 0.3567
Echinococcus multilocularis regulator of G protein signaling 7 0.0023 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Brugia malayi GnHR receptor homolog 0.0045 0.0105 0.0104
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0027 0.005 0.0091
Schistosoma mansoni neuropeptide receptor 0.0045 0.0105 0.0104
Onchocerca volvulus 0.0088 0.0227 0.1351
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0027 0.005 0.005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0022 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0002 0.0012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0037 0.0062
Onchocerca volvulus 0.0045 0.0105 0.0615
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.002 0.0054
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.0073 0.0186 0.09
Onchocerca volvulus 0.0584 0.1667 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0045 0.0105 0.0104
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.001 0.0002 0.0012
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0584 0.1667 0.1667
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0018 0.008
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0099 0.0259 1
Echinococcus granulosus dihydrofolate reductase 0.0173 0.0474 0.0474
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0083 0.0083
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0067 0.0169 0.0169
Brugia malayi ecdysone receptor 0.0012 0.0009 0.0009
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0045 0.0105 0.0104
Trypanosoma brucei RNA polymerase I second largest subunit 0.001 0.0002 0.0006
Brugia malayi jmjC domain containing protein 0.0094 0.0245 0.0245
Schistosoma mansoni hypothetical protein 0.0035 0.0074 0.0074
Brugia malayi steroid hormone receptor 0.0026 0.005 0.005
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0045 0.0105 0.0105
Toxoplasma gondii aspartyl protease 0.0017 0.0022 0.0833
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0074 0.0074
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0027 0.005 0.0049
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0045 0.0105 0.0104
Loa Loa (eye worm) 6-phosphofructokinase 0.0124 0.0333 0.0332
Onchocerca volvulus 0.0012 0.0009 0.0041
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0067 0.0066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0018 0.0686
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.0471 0.0471
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0066 0.0165 0.0796
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0012 0.0009 0.0009
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0012 0.0008 0.0008
Schistosoma mansoni nAChR subunit 0.0012 0.0008 0.0008
Echinococcus multilocularis Regulator of G protein signaling 20 0.0023 0.0038 0.0038
Echinococcus multilocularis axis inhibition protein axin 0.0023 0.0038 0.0038
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.027 0.0756 0.9361
Brugia malayi jmjC domain containing protein 0.0036 0.0079 0.0079
Plasmodium vivax importin-beta 2, putative 0.0056 0.0136 0.0653
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.011 0.0291 0.0291
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.005 0.005
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0041 0.0093 0.0276
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.005 0.005
Plasmodium falciparum plasmepsin IX 0.0017 0.0022 0.0102

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 15 nM In vitro inhibition of potassium-contracted rabbit aorta strips ChEMBL. 1387168
Max/average (functional) = 0 In vivo evaluation for the antihypertensive effect in the spontaneously hypertensive rat is % decrease in blood pressure during post drug administration at 45 umol/kg peroral; 80/46 ChEMBL. 1387168
Max/average (functional) = 0 In vivo evaluation for the antihypertensive effect in the spontaneously hypertensive rat is % decrease in blood pressure during post drug administration at 15 uM/kg peroral; 50/28 ChEMBL. 1387168
Max/average (functional) = 0 In vivo evaluation for the antihypertensive effect in the spontaneously hypertensive rat is % decrease in blood pressure during post drug administration at 5 umol/kg ; 40/18 ChEMBL. 1387168
Max/average (functional) = 0 In vivo evaluation for the antihypertensive effect in the spontaneously hypertensive rat is % decrease in blood pressure during post drug administration at 1.7 umol/kg peroral; 33/16 ChEMBL. 1387168

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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