Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0343 | 0.706 | 1 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus granulosus | Fibronectin type III | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | titin | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | Phosphotidylinositol phosphatase PTPRQ | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0343 | 0.706 | 0.706 |
Brugia malayi | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | neuroglian | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | UNCoordinated family member | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | neuroglian | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus multilocularis | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 30. | 0.0343 | 0.706 | 1 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Brugia malayi | myotactin form A | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0343 | 0.706 | 1 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Schistosoma mansoni | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Brugia malayi | protein unc-22 | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0343 | 0.706 | 0.706 |
Brugia malayi | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | titin | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | titin | 0.0343 | 0.706 | 0.706 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.706 | 0.706 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | usherin | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | nephrin | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | titin | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | EG95 | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | neuroglian | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0343 | 0.706 | 1 |
Brugia malayi | SPRY domain containing protein | 0.0343 | 0.706 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | Fibronectin, type III | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | titin | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0343 | 0.706 | 1 |
Brugia malayi | myotactin form B | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | myosin-binding protein-related | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | nephrin | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Trypanosoma brucei | Fibronectin type III domain containing protein, putative | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Lethal protein 805 | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 32 | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | projectin | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | hemicentin | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Phosphotidylinositol phosphatase PTPRQ | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | Netrin receptor DCC | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | nephrin | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | G1Y162 protein | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | Netrin receptor DCC | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Phosphotidylinositol phosphatase PTPRQ | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus multilocularis | titin | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus granulosus | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | lethal protein 805 | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | usherin | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | tripartite motif protein trim9 | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Netrin receptor DCC | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | Netrin receptor DCC | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Lethal protein 805 | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | hypothetical protein | 0.0343 | 0.706 | 0.706 |
Echinococcus multilocularis | anosmin 1 | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | titin | 0.0343 | 0.706 | 0.706 |
Onchocerca volvulus | 0.0343 | 0.706 | 1 | |
Echinococcus granulosus | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Echinococcus granulosus | contactin | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0343 | 0.706 | 1 |
Loa Loa (eye worm) | myotactin form A | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0343 | 0.706 | 0.706 |
Loa Loa (eye worm) | hypothetical protein | 0.0343 | 0.706 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0343 | 0.706 | 0.706 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0343 | 0.706 | 0.706 |
Echinococcus granulosus | roundabout 2 | 0.0343 | 0.706 | 0.706 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (ADMET) | > 10 uM | Cytotoxicity against human HuH7 cells infected with HCV1b by Alamar blue fluorescence assay | ChEMBL. | 24521299 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.