Detailed information for compound 1905836

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 407.481 | Formula: C24H26FN3O2
  • H donors: 0 H acceptors: 2 LogP: 3.24 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)n1c(=O)c(C)nc2c1cccc2
  • InChi: 1S/C24H26FN3O2/c1-17-24(30)28(22-6-3-2-5-21(22)26-17)20-12-15-27(16-13-20)14-4-7-23(29)18-8-10-19(25)11-9-18/h2-3,5-6,8-11,20H,4,7,12-16H2,1H3
  • InChiKey: PNYFUXOIQZKPGY-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1763
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0033 0.0086 0.0086
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Onchocerca volvulus 0.0026 0.0029 0.0078
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Brugia malayi ORL1-like opioid receptor 0.0069 0.0351 0.0351
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0033 0.0086 0.0086
Toxoplasma gondii proteasome subunit beta type, putative 0.0055 0.0248 0.0642
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0026 0.0029 0.0029
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0033 0.0086 0.0086
Schistosoma mansoni neuropeptide receptor 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0069 0.0351 0.154
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0055 0.0248 0.0248
Echinococcus granulosus signal transduction protein lnk realted 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0318 0.2214 0.2214
Brugia malayi hypothetical protein 0.0062 0.0301 0.0301
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0318 0.2214 1
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0076 0.0406 0.0406
Brugia malayi Trypsin family protein 0.0208 0.1392 0.1392
Plasmodium falciparum tubulin beta chain 0.0034 0.0088 0.0313
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0033 0.0086 0.0337
Brugia malayi AKH receptor 0.0069 0.0351 0.0351
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0086 0.0086
Schistosoma mansoni tensin 0.0026 0.0029 0.0029
Entamoeba histolytica cysteine protease, putative 0.0318 0.2214 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0028 0.0043 0.0066
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus granulosus chromobox protein 1 0.0076 0.0406 0.0406
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0055 0.0248 0.0642
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0028 0.0043 0.0107
Onchocerca volvulus 0.0192 0.1273 0.5728
Brugia malayi Associated with TFs and helicases family protein 0.0076 0.0406 0.0406
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0086 0.0086
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni two-pore calcium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis hyperpolarization activated cyclic 0.0033 0.0086 0.0086
Onchocerca volvulus Neuropeptide F receptor homolog 0.0069 0.0351 0.154
Echinococcus granulosus growth factor receptor bound protein 2 0.0026 0.0029 0.0029
Echinococcus multilocularis G-protein coupled receptor, putative 0.0069 0.0351 0.0351
Brugia malayi proteasome subunit beta type 2 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Onchocerca volvulus Cathepsin L homolog 0.0318 0.2214 1
Schistosoma mansoni cathepsin D (A01 family) 0.0775 0.5627 0.5627
Plasmodium falciparum serine repeat antigen 6 0.0116 0.07 0.3102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0069 0.0351 0.154
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0118 0.0716 0.0698
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0517 0.0517
Brugia malayi G protein-coupled receptor F59B2.13 0.0069 0.0351 0.0351
Schistosoma mansoni growth factor receptor-bound protein 0.0026 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Schistosoma mansoni amine GPCR 0.0069 0.0351 0.0351
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0208 0.1392 0.1392
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0118 0.0716 0.0698
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Schistosoma mansoni tensin 0.0026 0.0029 0.0029
Loa Loa (eye worm) calcium channel 0.0033 0.0086 0.0086
Schistosoma mansoni ap endonuclease 0.0028 0.0043 0.0043
Loa Loa (eye worm) animal heme peroxidase 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0026 0.0032 0.0032
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.07 0.3102
Schistosoma mansoni opsin-like receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) SH2 domain-containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0026 0.0032 0.0032
Schistosoma mansoni transient receptor potential channel 0.0033 0.0086 0.0086
Echinococcus multilocularis somatostatin receptor 0.0069 0.0351 0.0351
Schistosoma mansoni suppressor of cytokine signaling 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0208 0.1392 0.6268
Entamoeba histolytica protein kinase, putative 0.0026 0.0029 0.0044
Onchocerca volvulus 0.0076 0.0406 0.1791
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.136 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0517 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0318 0.2214 0.2214
Echinococcus multilocularis Tubulin beta 2C chain 0.0034 0.0088 0.0088
Schistosoma mansoni tyrosine kinase 0.0026 0.0032 0.0032
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis cathepsin L cysteine protease 0.0318 0.2214 0.2214
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Schistosoma mansoni cathepsin B (C01 family) 0.0116 0.07 0.07
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Schistosoma mansoni amine GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus voltage gated hydrogen channel 1 0.0033 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0026 0.0029 0.0078
Entamoeba histolytica hypothetical protein 0.0076 0.0406 0.1763
Echinococcus granulosus 7TM GPCR rhodopsin 0.0069 0.0351 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0069 0.0351 0.0351
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0116 0.07 0.3102
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0121 0.0737 0.0737
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Toxoplasma gondii beta-1 tubulin, putative 0.0034 0.0088 0.0193
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0037 0.011 0.0255
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0116 0.07 0.3102
Echinococcus multilocularis fmrfamide receptor 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine proteinase, putative 0.0318 0.2214 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0033 0.0086 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Plasmodium falciparum plasmepsin X 0.0062 0.0301 0.1282
Brugia malayi cathepsin L-like precursor 0.0318 0.2214 0.2214
Schistosoma mansoni neuropeptide receptor 0.0069 0.0351 0.0351
Echinococcus granulosus hypothetical protein 0.0033 0.0086 0.0086
Schistosoma mansoni amine GPCR 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Schistosoma mansoni neuropeptide F-like receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0318 0.2214 1
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0076 0.0406 0.1088
Loa Loa (eye worm) hypothetical protein 0.0208 0.1392 0.1392
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Protein kinase domain containing protein 0.0026 0.0032 0.0032
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0024 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0517 0.0517
Echinococcus granulosus jumonji domain containing protein 0.0025 0.0024 0.0024
Schistosoma mansoni cathepsin F (C01 family) 0.0318 0.2214 0.2214
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus granulosus tyrosine protein kinase Lyn 0.0026 0.0032 0.0032
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0033 0.0086 0.0086
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0062 0.0301 0.0301
Echinococcus granulosus hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni chromobox protein 0.0076 0.0406 0.0406
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Giardia lamblia Cathepsin B precursor 0.05 0.3576 1
Onchocerca volvulus 0.0069 0.0351 0.154
Trypanosoma cruzi cruzipain precursor, putative 0.0318 0.2214 0.2199
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0028 0.0043 0.0023
Echinococcus granulosus hyperpolarization activated cyclic 0.0033 0.0086 0.0086
Echinococcus multilocularis SH2 motif 0.0026 0.0029 0.0029
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0033 0.0086 0.0086
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0029 0.0029
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Trichomonas vaginalis set domain proteins, putative 0.0147 0.0934 0.2571
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0086 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Entamoeba histolytica SH2 domain containing protein 0.0026 0.0029 0.0044
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0318 0.2214 0.2214
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0116 0.07 0.3102
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0033 0.0086 0.0086
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1088
Giardia lamblia Cysteine protease 0.0116 0.07 0.1914
Echinococcus multilocularis tyrosine protein kinase Blk 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0069 0.0351 0.0351
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Trichomonas vaginalis rotamase, putative 0.0118 0.0716 0.1959
Trypanosoma cruzi cysteine peptidase, putative 0.0116 0.07 0.0682
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0118 0.0716 0.1895
Echinococcus multilocularis tyrosine protein kinase Abl 0.0026 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Echinococcus granulosus Tubulin beta 2C chain 0.0034 0.0088 0.0088
Brugia malayi hypothetical protein 0.0076 0.0406 0.0406
Echinococcus granulosus somatostatin receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis Tubulin beta 2C chain 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Leishmania major hypothetical protein, conserved 0.0033 0.0086 0.0181
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0033 0.0086 0.0086
Plasmodium vivax aspartyl protease, putative 0.0062 0.0301 0.1282
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0188 0.0188
Trypanosoma cruzi major cysteine proteinase, putative 0.0116 0.07 0.0682
Schistosoma mansoni tensin-related 0.0034 0.0092 0.0092
Brugia malayi exodeoxyribonuclease III family protein 0.0028 0.0043 0.0043
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0055 0.0248 0.5
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus multilocularis SH2 motif 0.0026 0.0029 0.0029
Echinococcus granulosus alpha 1A adrenergic receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0026 0.0032 0.0032
Echinococcus granulosus tensin 0.0026 0.0029 0.0029
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0076 0.0406 0.1791
Brugia malayi G protein-coupled receptor 0.0069 0.0351 0.0351
Brugia malayi CHD4 protein 0.0076 0.0406 0.0406
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0263 0.18 0.5007
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0026 0.0032 0.0032
Loa Loa (eye worm) voltage-dependent calcium channel 0.0033 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase ABL1 0.0026 0.0032 0.0032
Echinococcus granulosus peroxidasin 0.0023 0.0012 0.0012
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus multilocularis 0.0026 0.0029 0.0029
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Echinococcus multilocularis microtubule associated protein 2 0.0433 0.3071 0.3071
Schistosoma mansoni growth hormone secretagogue receptor 0.0069 0.0351 0.0351
Schistosoma mansoni chromobox protein 0.1307 0.9605 0.9605
Onchocerca volvulus Cathepsin L homolog 0.0116 0.07 0.3125
Loa Loa (eye worm) TK protein kinase 0.0026 0.0032 0.0032
Plasmodium falciparum serine repeat antigen 4 0.0116 0.07 0.3102
Onchocerca volvulus 0.0095 0.0545 0.2419
Brugia malayi Serotonin receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis calcium activated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0092
Giardia lamblia Cathepsin B precursor 0.05 0.3576 1
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0086 0.0086
Echinococcus multilocularis cathepsin b 0.136 1 1
Plasmodium vivax heterochromatin protein 1, putative 0.0076 0.0406 0.1763
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Tyrosine-protein kinase abl-1 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0318 0.2214 1
Plasmodium vivax aspartyl protease, putative 0.0062 0.0301 0.1282
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Onchocerca volvulus 0.0069 0.0351 0.154
Brugia malayi Muscleblind-like protein 0.0312 0.2169 0.2169
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0351 0.0351
Schistosoma mansoni microtubule-associated protein tau 0.0433 0.3071 0.3071
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0086 0.0086
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Onchocerca volvulus 0.0318 0.2214 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0033 0.0086 0.0086
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0208 0.1392 0.1392
Echinococcus granulosus allatostatin A receptor 0.0069 0.0351 0.0351
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0026 0.0029 0.0078
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0043 0.0107
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) animal heme peroxidase 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0351 0.0351
Brugia malayi aspartic protease BmAsp-1, identical 0.0062 0.0301 0.0301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0086 0.0086
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Brugia malayi Melatonin receptor type 1A 0.0069 0.0351 0.0351
Brugia malayi cathepsin F-like cysteine proteinase 0.0116 0.07 0.07
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0033 0.0086 0.0086
Echinococcus granulosus chromobox protein 2 0.1307 0.9605 0.9605
Onchocerca volvulus Cathepsin F homolog 0.0318 0.2214 1
Loa Loa (eye worm) tubulin beta-1 chain 0.0034 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0737 0.2018
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0033 0.0086 0.0086
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0086 0.0086
Trypanosoma brucei beta tubulin 0.0034 0.0088 0.0193
Echinococcus multilocularis g-protein coupled receptor 0.0069 0.0351 0.0351
Plasmodium vivax aspartyl proteinase, putative 0.0062 0.0301 0.1282
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0116 0.07 0.3102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus microtubule associated protein 2 0.0433 0.3071 0.3071
Echinococcus multilocularis cathepsin L 0.0116 0.07 0.07
Echinococcus granulosus calcium activated potassium channel 0.0033 0.0086 0.0086
Schistosoma mansoni ryanodine receptor related 0.0033 0.0086 0.0086
Giardia lamblia Beta tubulin 0.0034 0.0088 0.0193
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0028 0.0043 0.0107
Echinococcus granulosus tachykinin peptides receptor 99D 0.0069 0.0351 0.0351
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus cathepsin l1 0.0318 0.2214 0.2214
Brugia malayi cytokine inducible SH2-containing protein 5 0.0026 0.0029 0.0029
Loa Loa (eye worm) tubulin beta-2A chain 0.0034 0.0088 0.0088
Brugia malayi hypothetical protein 0.0026 0.0032 0.0032
Echinococcus multilocularis Tubulin beta 2C chain 0.0034 0.0088 0.0088
Leishmania major cysteine peptidase A (CPA) 0.0318 0.2214 0.5969
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.05 0.3576 0.3576
Echinococcus multilocularis tensin 0.0034 0.0092 0.0092
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Echinococcus multilocularis cathepsin b 0.136 1 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Plasmodium vivax aspartyl proteinase, putative 0.0263 0.18 0.8115
Brugia malayi Dopamine receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.07 0.07
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Schistosoma mansoni hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0318 0.2214 0.2214
Trichomonas vaginalis Heterochromatin protein, putative 0.0076 0.0406 0.1088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0116 0.07 0.1914
Plasmodium falciparum heterochromatin protein 1 0.0076 0.0406 0.1763
Echinococcus multilocularis voltage gated potassium channel 0.0033 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0351 0.0351
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0116 0.07 0.3102
Echinococcus granulosus two pore calcium channel protein 2 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Plasmodium falciparum cysteine proteinase falcipain 1 0.0116 0.07 0.3102
Loa Loa (eye worm) tubulin beta chain 0.0034 0.0088 0.0088
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0069 0.0351 0.0351
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0029 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.136 1 1
Schistosoma mansoni chromobox protein 0.0076 0.0406 0.0406
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0026 0.0029 0.0029
Echinococcus granulosus NCK adaptor protein 0.0026 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0116 0.07 0.1914
Schistosoma mansoni ap endonuclease 0.0028 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Schistosoma mansoni tensin-related 0.0034 0.0092 0.0092
Echinococcus granulosus tyrosine protein kinase Src64B 0.0026 0.0032 0.0032
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0318 0.2214 0.2199
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Loa Loa (eye worm) G-protein coupled receptor 0.0069 0.0351 0.0351
Brugia malayi hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine kinase 0.0026 0.0032 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0116 0.07 0.3102
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Trichomonas vaginalis tubulin beta chain, putative 0.0034 0.0088 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) TK/ABL protein kinase 0.0026 0.0032 0.0032
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Echinococcus granulosus shaker cognate 0.0033 0.0086 0.0086
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Schistosoma mansoni neuropeptide receptor 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0318 0.2214 1
Loa Loa (eye worm) blistered cuticle protein 3 0.0023 0.0012 0.0012
Brugia malayi hypothetical protein 0.0023 0.0012 0.0012
Plasmodium falciparum serine repeat antigen 9 0.0116 0.07 0.3102
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus tubulin beta 4A class IVa 0.0034 0.0088 0.0088
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0406 0.1763
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Schistosoma mansoni vav2 0.0026 0.0029 0.0029
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0033 0.0086 0.0086
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0086 0.0086
Echinococcus granulosus Tubulin beta 2C chain 0.0034 0.0088 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Loa Loa (eye worm) ryanodine receptor 0.0033 0.0086 0.0086
Entamoeba histolytica tubulin family protein 0.0034 0.0088 0.0313
Onchocerca volvulus 0.0318 0.2214 1
Toxoplasma gondii aspartyl protease ASP1 0.0263 0.18 0.5007
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0086 0.0086
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0263 0.18 0.18
Leishmania major hypothetical protein, unknown function 0.0033 0.0086 0.0181
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Echinococcus granulosus tyrosine kinase 0.0026 0.0032 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0069 0.0351 0.0351
Echinococcus multilocularis cysteine protease 0.0318 0.2214 0.2214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0351 0.0351
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0033 0.0086 0.0187
Echinococcus multilocularis jumonji domain containing protein 0.0025 0.0024 0.0024
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0033 0.0086 0.0067
Echinococcus granulosus short transient receptor potential channel 6 0.0033 0.0086 0.0086
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Plasmodium vivax plasmepsin IV, putative 0.0263 0.18 0.8115
Plasmodium vivax vivapain-2 0.0318 0.2214 1
Plasmodium falciparum plasmepsin VIII, putative 0.0062 0.0301 0.1282
Echinococcus granulosus sex peptide receptor 0.0069 0.0351 0.0351
Toxoplasma gondii aspartyl protease 0.0062 0.0301 0.0791
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus multilocularis tubulin beta 1 chain 0.0034 0.0088 0.0088
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus multilocularis proteasome (prosome, macropain) 0.0055 0.0248 0.0248
Brugia malayi chromobox protein homolog 3 0.0076 0.0406 0.0406
Echinococcus granulosus Tubulin beta 2C chain 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus neuropeptides capa receptor 0.0069 0.0351 0.0351
Echinococcus granulosus cathepsin l1 0.0318 0.2214 0.2214
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0116 0.07 0.3102
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.07 0.3102
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0026 0.0029 0.0029
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0517 0.0517
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Schistosoma mansoni voltage-gated ion channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi hypothetical protein 0.0033 0.0086 0.0086
Echinococcus multilocularis N chimaerin 0.0026 0.0029 0.0029
Schistosoma mansoni myosin xvIII 0.0069 0.0351 0.0351
Brugia malayi jmjC domain containing protein 0.0059 0.0279 0.0279
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.05 0.3576 0.9674
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0037 0.011 0.0091
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Plasmodium vivax unspecified product 0.0116 0.07 0.3102
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.136 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Brugia malayi cathepsin Z-like cysteine proteinase 0.0116 0.07 0.07
Schistosoma mansoni shc transforming protein 0.0034 0.0092 0.0092
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0026 0.0032 0.0092
Plasmodium falciparum proteasome subunit beta type-5 0.0055 0.0248 0.104
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Plasmodium falciparum plasmepsin V 0.0062 0.0301 0.1282
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Trichomonas vaginalis tubulin, putative 0.0034 0.0088 0.0193
Schistosoma mansoni biogenic amine receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0318 0.2214 0.2214
Brugia malayi Animal haem peroxidase family protein 0.0023 0.0012 0.0012
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0116 0.07 0.3102
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0033 0.0086 0.0086
Plasmodium falciparum serine repeat antigen 7 0.0116 0.07 0.3102
Schistosoma mansoni tyrosine kinase 0.0062 0.0299 0.0299
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Brugia malayi Protein kinase domain containing protein 0.0026 0.0032 0.0032
Echinococcus multilocularis chromobox protein 1 0.0076 0.0406 0.0406
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0116 0.07 0.1914
Echinococcus multilocularis c src tyrosine kinase 0.0026 0.0032 0.0032
Loa Loa (eye worm) melatonin receptor type 1A 0.0069 0.0351 0.0351
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Brugia malayi Pre-SET motif family protein 0.0129 0.0801 0.0801
Echinococcus granulosus ryanodine receptor 44f 0.0033 0.0086 0.0086
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0076 0.0406 0.0406
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Echinococcus granulosus neuropeptide receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0263 0.18 0.18
Brugia malayi Eukaryotic aspartyl protease family protein 0.0062 0.0301 0.0301
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0043 0.0066
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni alpha-1 adrenergic receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis tubulin gamma chain, putative 0.0034 0.0088 0.0193
Toxoplasma gondii hypothetical protein 0.0033 0.0086 0.0187
Treponema pallidum exodeoxyribonuclease (exoA) 0.0028 0.0043 0.5
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Trichomonas vaginalis rotamase, putative 0.0121 0.0737 0.2018
Loa Loa (eye worm) helicase 0.0076 0.0406 0.0406
Trichomonas vaginalis tubulin epsilon chain, putative 0.0034 0.0088 0.0193
Trypanosoma brucei beta tubulin 0.0034 0.0088 0.0193
Onchocerca volvulus 0.0069 0.0351 0.154
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0055 0.0248 0.104
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0069 0.0351 0.0351
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis cathepsin L 0.0116 0.07 0.07
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.0279 0.0279
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0033 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0026 0.0032 0.0032
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0086 0.0086
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0318 0.2214 0.2214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Schistosoma mansoni neuropeptide receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0312 0.2169 0.2169
Loa Loa (eye worm) STAT protein 0.0977 0.7139 0.7139
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Brugia malayi Cyclic-nucleotide gated cation channel 0.0033 0.0086 0.0086
Plasmodium vivax vivapain-2 0.0318 0.2214 1
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) ion channel NompC 0.0033 0.0086 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Onchocerca volvulus 0.0026 0.0029 0.0078
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0033 0.0086 0.0086
Entamoeba histolytica tubulin family protein 0.0034 0.0088 0.0313
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.05 0.3576 1
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.07 0.07
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0516 0.3696 0.3696
Plasmodium vivax serine-repeat antigen (SERA) 0.0116 0.07 0.3102
Echinococcus multilocularis voltage dependent calcium channel 0.0033 0.0086 0.0086
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis ap endonuclease, putative 0.0028 0.0043 0.0066
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0055 0.0248 0.0642
Brugia malayi cation channel family protein 0.0033 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.0318 0.2214 0.2199
Schistosoma mansoni peroxidasin 0.0023 0.0012 0.0012
Giardia lamblia Cathepsin B precursor 0.0116 0.07 0.1914
Onchocerca volvulus 0.0318 0.2214 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Echinococcus granulosus cathepsin b 0.136 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus granulosus tyrosine kinase 0.0026 0.0032 0.0032
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Brugia malayi Valyl-tRNA synthetase 0.0076 0.0406 0.0406
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Brugia malayi larval opioid receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis hypothetical protein 0.0076 0.0406 0.1088
Loa Loa (eye worm) BEN-1 protein 0.0034 0.0088 0.0088
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Giardia lamblia Hypothetical protein 0.0116 0.07 0.1914
Giardia lamblia Cathepsin B precursor 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Protein kinase domain containing protein 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0026 0.0032 0.0092
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0029 0.0029
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0116 0.07 0.3102
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0037 0.011 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus fmrfamide receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Pepsin A precursor 0.0062 0.0301 0.0301
Echinococcus granulosus cathepsin L cysteine protease 0.0116 0.07 0.07
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0069 0.0351 0.0351
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0033 0.0086 0.0086
Schistosoma mansoni histamine h1 receptor 0.0069 0.0351 0.0351
Plasmodium falciparum plasmepsin IV 0.0263 0.18 0.8115
Trypanosoma cruzi cysteine peptidase, putative 0.0318 0.2214 0.2199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Trypanosoma cruzi cysteine protease, putative 0.0116 0.07 0.0682
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0069 0.0351 0.0351
Schistosoma mansoni hypothetical protein 0.0069 0.0351 0.0351
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0076 0.0406 0.1763
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0318 0.2214 0.2214
Plasmodium vivax aspartyl protease, putative 0.0062 0.0301 0.1282
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0086 0.0086
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0263 0.18 0.18
Schistosoma mansoni cathepsin F (C01 family) 0.0318 0.2214 0.2214
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0026 0.0029 0.0029
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0516 0.3696 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.0279 0.0279
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus granulosus peptide allatostatin:somatostatin 0.0069 0.0351 0.0351
Leishmania major proteasome beta 5 subunit, putative 0.0055 0.0248 0.0621
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0026 0.0029 0.0078
Entamoeba histolytica cysteine proteinase 1, putative 0.0116 0.07 0.3102
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Echinococcus multilocularis neuropeptide FF receptor 2 0.0069 0.0351 0.0351
Echinococcus granulosus c src tyrosine kinase 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0026 0.0032 0.0092
Onchocerca volvulus 0.0026 0.0029 0.0078
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0026 0.0029 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0055 0.0248 0.0229
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine proteinase, putative 0.0318 0.2214 1
Schistosoma mansoni adapter molecule crk 0.0026 0.0029 0.0029
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0026 0.0032 0.0058
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0033 0.0086 0.0187
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.011 0.0247
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Echinococcus multilocularis orexin receptor type 2 0.0069 0.0351 0.0351
Entamoeba histolytica hypothetical protein 0.0116 0.07 0.3102
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) SRC-1 0.0026 0.0032 0.0032
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0069 0.0351 0.0351
Plasmodium vivax proteasome subunit beta type-5, putative 0.0055 0.0248 0.104
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0116 0.07 0.3102
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Giardia lamblia Hypothetical protein 0.0116 0.07 0.1914
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0406 0.1763
Echinococcus granulosus G protein coupled receptor 139 0.0069 0.0351 0.0351
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Loa Loa (eye worm) hypothetical protein 0.0263 0.18 0.18
Schistosoma mansoni hypothetical protein 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0318 0.2214 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0026 0.0032 0.0032
Echinococcus granulosus cysteine protease 0.0116 0.07 0.07
Echinococcus multilocularis tubulin subunit beta 0.0034 0.0088 0.0088
Brugia malayi G-protein coupled receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus biogenic amine 5HT receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0076 0.0406 0.0406
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0069 0.0351 0.0351
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Echinococcus multilocularis muscleblind protein 1 0.0312 0.2169 0.2169
Plasmodium falciparum serine repeat antigen 8 0.0116 0.07 0.3102
Echinococcus granulosus SH2 domain containing adapter protein F 0.0026 0.0029 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Brugia malayi RhoGAP domain containing protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) SH2 domain-containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus granulosus Chromobox protein 3 0.0076 0.0406 0.0406
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0121 0.0737 0.0737
Echinococcus granulosus suppressor of cytokine signaling 7 0.0026 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0116 0.07 0.1914
Schistosoma mansoni tyrosine kinase 0.0088 0.0492 0.0492
Toxoplasma gondii preprocathepsin c precursor, putative 0.0116 0.07 0.1914
Echinococcus granulosus sodium leak channel non selective protein 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0069 0.0351 0.154
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0086 0.0086
Echinococcus multilocularis short transient receptor potential channel 6 0.0033 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Brugia malayi Protein cec-1. 0.0076 0.0406 0.0406
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0517 0.0517
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Schistosoma mansoni opsin-like receptor 0.0069 0.0351 0.0351
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Echinococcus multilocularis two pore calcium channel protein 2 0.0033 0.0086 0.0086
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0263 0.18 0.5007
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus multilocularis cysteine protease 0.0318 0.2214 0.2214
Loa Loa (eye worm) aspartyl protease 6 0.0062 0.0301 0.0301
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0033 0.0086 0.0086
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0028 0.0043 0.0043
Giardia lamblia Cathepsin B precursor 0.05 0.3576 1
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Plasmodium falciparum plasmepsin VII 0.0062 0.0301 0.1282
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0069 0.0351 0.154
Toxoplasma gondii cathepsin B 0.05 0.3576 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0069 0.0351 0.0351
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0055 0.0248 0.0248
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0026 0.0032 0.0032
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus multilocularis tyrosine protein kinase Srms 0.0026 0.0032 0.0032
Brugia malayi Protein kinase domain containing protein 0.0026 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Echinococcus multilocularis chromobox protein 2 0.1307 0.9605 0.9605
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi neuropeptide F receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0031 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0062 0.0301 0.0301
Plasmodium falciparum serine repeat antigen 3 0.0116 0.07 0.3102
Brugia malayi Animal haem peroxidase family protein 0.0023 0.0012 0.0012
Echinococcus multilocularis hyperpolarization activated cyclic 0.0033 0.0086 0.0086
Echinococcus multilocularis transfer RNA-Gly 0.0033 0.0086 0.0086
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Trypanosoma cruzi major cysteine proteinase, putative 0.0116 0.07 0.0682
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0076 0.0406 0.1791
Brugia malayi Tensin 0.0026 0.0029 0.0029
Loa Loa (eye worm) voltage-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0517 0.0517
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0076 0.0406 0.1763
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0069 0.0351 0.0351
Echinococcus granulosus Tubulin beta 2C chain 0.0034 0.0088 0.0088
Brugia malayi sulfakinin receptor protein 0.0069 0.0351 0.0351
Brugia malayi Angiotensin-converting enzyme family protein 0.0605 0.4356 0.4356
Echinococcus granulosus suppressor of cytokine signaling 6 0.0026 0.0029 0.0029
Plasmodium vivax unspecified product 0.0116 0.07 0.3102
Echinococcus granulosus muscleblind protein 0.0312 0.2169 0.2169
Onchocerca volvulus 0.0116 0.07 0.3125
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) BEN-1 protein 0.0034 0.0088 0.0088
Schistosoma mansoni tyrosine kinase 0.0026 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Echinococcus multilocularis neuropeptides capa receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0026 0.0032 0.0032
Brugia malayi putative neuropeptide receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0034 0.0088 0.0088
Echinococcus granulosus cathepsin l cysteine peptidase 0.0318 0.2214 0.2214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus granulosus voltage gated potassium channel 0.0033 0.0086 0.0086
Giardia lamblia Cysteine protease 0.0116 0.07 0.1914
Schistosoma mansoni chromobox protein 0.0076 0.0406 0.0406
Mycobacterium ulcerans proteasome PrcB 0.0055 0.0248 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.07 0.07
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0116 0.07 0.07
Onchocerca volvulus 0.0076 0.0406 0.1791
Schistosoma mansoni hypothetical protein 0.0076 0.0406 0.0406
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0076 0.0406 0.1088
Plasmodium vivax plasmepsin V, putative 0.0062 0.0301 0.1282
Toxoplasma gondii cathepsin CPC1 0.0116 0.07 0.1914
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0069 0.0351 0.0351
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0517 0.0517
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0033 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Echinococcus granulosus tm gpcr rhodopsin 0.0069 0.0351 0.0351
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Schistosoma mansoni nck2/grb4 0.0026 0.0029 0.0029
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0069 0.0351 0.0351
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Echinococcus granulosus hyperpolarization activated cyclic 0.0033 0.0086 0.0086
Brugia malayi Peroxidasin 0.0023 0.0012 0.0012
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0026 0.0029 0.0029
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0026 0.0029 0.0029
Echinococcus granulosus short transient receptor potential channel 6 0.0033 0.0086 0.0086
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi neuropeptide F receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi olfactory channel protein osm-9 0.0033 0.0086 0.0086
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0116 0.07 0.1914
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0029 0.0029
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0086 0.0187
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0208 0.1392 0.1392
Echinococcus granulosus neuropeptide receptor A26 0.0069 0.0351 0.0351
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0026 0.0032 0.0032
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0118 0.0716 0.1959
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) cysteine protease 0.0318 0.2214 0.2214
Echinococcus granulosus cathepsin L 0.0116 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0033 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.0318 0.2214 0.2199
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0116 0.07 0.1914
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Schistosoma mansoni vesicular amine transporter 0.0033 0.0086 0.0086
Echinococcus granulosus serotonin receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) animal heme peroxidase 0.0023 0.0012 0.0012
Echinococcus granulosus SH2 motif 0.0026 0.0029 0.0029
Schistosoma mansoni growth factor receptor-bound protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0116 0.07 0.07
Loa Loa (eye worm) SH2 domain-containing protein 0.0026 0.0029 0.0029
Brugia malayi cathepsin L-like cysteine proteinase 0.0116 0.07 0.07
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Schistosoma mansoni transient receptor potential channel 4 0.0033 0.0086 0.0086
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Giardia lamblia Cathepsin L-like protease 0.0116 0.07 0.1914
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0318 0.2214 0.617
Trypanosoma brucei beta tubulin 0.0034 0.0088 0.0193
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Echinococcus granulosus neuropeptides capa receptor 0.0069 0.0351 0.0351
Trypanosoma cruzi beta tubulin, putative 0.0034 0.0088 0.0069
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0116 0.07 0.07
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Onchocerca volvulus 0.0026 0.0032 0.0092
Trichomonas vaginalis tubulin alpha chain, putative 0.0034 0.0088 0.0193
Echinococcus multilocularis allatostatin A receptor 0.0069 0.0351 0.0351
Brugia malayi Blistered cuticle protein 3 0.0023 0.0012 0.0012
Toxoplasma gondii aspartyl protease ASP3 0.0062 0.0301 0.0791
Brugia malayi hypothetical protein 0.0062 0.0301 0.0301
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0033 0.0086 0.0086
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.011 0.0255
Plasmodium falciparum plasmepsin VI 0.0263 0.18 0.8115
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Schistosoma mansoni amine GPCR 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Brugia malayi Heterochromatin protein 1 0.0076 0.0406 0.0406
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0116 0.07 0.07
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0062 0.0301 0.1311
Echinococcus granulosus voltage dependent calcium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0033 0.0086 0.0086
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0033 0.0086 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis Chromobox protein 3 0.0076 0.0406 0.0406
Echinococcus multilocularis sex peptide receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) voltage-gated potassium channel 0.0033 0.0086 0.0086
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0033 0.0086 0.0086
Plasmodium vivax vivapain-3 0.0116 0.07 0.3102
Entamoeba histolytica cysteine proteinase 2 0.0116 0.07 0.3102
Echinococcus granulosus N chimaerin 0.0026 0.0029 0.0029
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Onchocerca volvulus 0.0033 0.0086 0.0337
Schistosoma mansoni biogenic amine receptor 0.0069 0.0351 0.0351
Toxoplasma gondii cathepsin CPL 0.0318 0.2214 0.617
Schistosoma mansoni memapsin-2 (A01 family) 0.0062 0.0301 0.0301
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.136 1 1
Brugia malayi Animal haem peroxidase family protein 0.0023 0.0012 0.0012
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0351 0.0351
Onchocerca volvulus Cathepsin L homolog 0.0318 0.2214 1
Schistosoma mansoni rotamase 0.0121 0.0737 0.0737
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0086 0.0187
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0026 0.0029 0.0029
Echinococcus granulosus g-protein coupled receptor 0.0069 0.0351 0.0351
Brugia malayi Papain family cysteine protease containing protein 0.0318 0.2214 0.2214
Brugia malayi SH2 domain containing protein 0.0026 0.0032 0.0032
Brugia malayi beta-tubulin, identical 0.0034 0.0088 0.0088
Echinococcus multilocularis tyrosine protein kinase shark 0.0088 0.0492 0.0492
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0095 0.0545 0.0545
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0033 0.0086 0.0086
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0033 0.0086 0.0086
Echinococcus granulosus hypothetical protein 0.0069 0.0351 0.0351
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0076 0.0406 0.1088
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0055 0.0248 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0086 0.0086
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0028 0.0043 0.0023
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Brugia malayi Sex muscle abnormal protein 5 0.0026 0.0029 0.0029
Echinococcus multilocularis growth factor receptor bound protein 2 0.0026 0.0029 0.0029
Onchocerca volvulus 0.0069 0.0351 0.154
Loa Loa (eye worm) animal heme peroxidase 0.0023 0.0012 0.0012
Echinococcus multilocularis neuropeptide receptor A26 0.0069 0.0351 0.0351
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0026 0.0029 0.0029
Echinococcus multilocularis tyrosine kinase 0.0026 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus sodium channel protein 0.0516 0.3696 0.3696
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.07 0.07
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Schistosoma mansoni neuropeptide f receptor 76f 0.0069 0.0351 0.0351
Entamoeba histolytica hypothetical protein 0.0076 0.0406 0.1763
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1763
Echinococcus granulosus neuropeptide s receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis SH2 domain containing protein 7 0.0026 0.0029 0.0029
Schistosoma mansoni biogenic amine receptor 0.0069 0.0351 0.0351
Echinococcus granulosus cathepsin b 0.136 1 1
Echinococcus granulosus tyrosine protein kinase Srms 0.0026 0.0032 0.0032
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Schistosoma mansoni transient receptor potential channel 0.0033 0.0086 0.0086
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0028 0.0043 0.0066
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0517 0.0517
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0116 0.07 0.3102
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0116 0.07 0.07
Trypanosoma cruzi cysteine proteinase, putative 0.0116 0.07 0.0682
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0069 0.0351 0.0351
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0116 0.07 0.3102
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0033 0.0086 0.0086
Plasmodium falciparum serine repeat antigen 2 0.0116 0.07 0.3102
Schistosoma mansoni hypothetical protein 0.0026 0.0029 0.0029
Echinococcus multilocularis SH2 motif 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Brugia malayi tRNA modification GTPase TrmE family protein 0.0026 0.0029 0.0029
Echinococcus multilocularis neuropeptide Y receptor 0.0069 0.0351 0.0351
Schistosoma mansoni hypothetical protein 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.136 1 1
Toxoplasma gondii beta tubulin 0.0034 0.0088 0.0193
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni cathepsin S (C01 family) 0.0116 0.07 0.07
Echinococcus granulosus cathepsin L 0.0116 0.07 0.07
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0116 0.07 0.3102
Loa Loa (eye worm) cathepsin B 0.05 0.3576 0.3576
Loa Loa (eye worm) G-protein coupled receptor 0.0069 0.0351 0.0351
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0069 0.0351 0.0351
Schistosoma mansoni calcium-activated potassium channel 0.0033 0.0086 0.0086
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0033 0.0086 0.0086
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0033 0.0086 0.0086
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0033 0.0086 0.0086
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0076 0.0406 0.0406
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0263 0.18 0.18
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Echinococcus multilocularis voltage gated potassium channel 0.0033 0.0086 0.0086
Echinococcus granulosus potassium large conductance calcium activated 0.0033 0.0086 0.0086
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1088
Trypanosoma cruzi cysteine peptidase, putative 0.0318 0.2214 0.2199
Schistosoma mansoni signal transduction protein lnk-related 0.0026 0.0029 0.0029
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0069 0.0351 0.0351
Schistosoma mansoni voltage-dependent calcium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) tubulin beta-4 chain 0.0034 0.0088 0.0088
Schistosoma mansoni amine GPCR 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0033 0.0086 0.0086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0069 0.0351 0.0351
Echinococcus multilocularis shaker cognate 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0026 0.0029 0.0029
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0086 0.0086
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0033 0.0086 0.0086
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1088
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0033 0.0086 0.0086
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0076 0.0406 0.1088
Loa Loa (eye worm) CHromoDomain protein family member 0.0076 0.0406 0.0406
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.07 0.3102
Brugia malayi SH2 domain containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0026 0.0029 0.0029
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0076 0.0406 0.0406
Loa Loa (eye worm) voltage-gated calcium channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0062 0.0301 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Echinococcus multilocularis cathepsin L cysteine protease 0.0318 0.2214 0.2214
Giardia lamblia Cathepsin B precursor 0.0116 0.07 0.1914
Onchocerca volvulus 0.0026 0.0032 0.0092
Brugia malayi GnHR receptor homolog 0.0069 0.0351 0.0351
Echinococcus multilocularis potassium large conductance calcium activated 0.0033 0.0086 0.0086
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0024 0.002 0.002
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0076 0.0406 0.0406
Trypanosoma brucei beta tubulin 0.0034 0.0088 0.0193
Giardia lamblia Beta tubulin 0.0034 0.0088 0.0193
Echinococcus granulosus tyrosine protein kinase Src42A 0.0026 0.0032 0.0032
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Onchocerca volvulus 0.0026 0.0032 0.0092
Echinococcus granulosus neuropeptide Y receptor 0.0069 0.0351 0.0351
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.07 0.07
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0026 0.0029 0.0029
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Brugia malayi M-phase phosphoprotein, mpp8 0.0076 0.0406 0.0406
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0069 0.0351 0.0351
Brugia malayi putative neuropeptide receptor NPR1 0.0069 0.0351 0.0351
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0318 0.2214 1
Brugia malayi Cathepsin L-like precursor 0.0318 0.2214 0.2214
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Echinococcus granulosus g protein coupled receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0086 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Plasmodium falciparum plasmepsin IX 0.0062 0.0301 0.1282
Echinococcus multilocularis G protein coupled receptor 139 0.0069 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0116 0.07 0.1914
Entamoeba histolytica cysteine proteinase, putative 0.0318 0.2214 1
Entamoeba histolytica hypothetical protein 0.0076 0.0406 0.1763
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Echinococcus multilocularis peroxidasin 0.0023 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase shark 0.0088 0.0492 0.0492
Toxoplasma gondii exonuclease III APE 0.0028 0.0043 0.0066
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0026 0.0032 0.0032
Echinococcus multilocularis tensin 0.0026 0.0029 0.0029
Echinococcus granulosus SHC transforming protein 3 0.0227 0.1532 0.1532
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0033 0.0086 0.0337
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Trypanosoma cruzi cysteine proteinase, putative 0.0116 0.07 0.0682
Trypanosoma brucei cysteine peptidase C (CPC) 0.05 0.3576 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0026 0.0029 0.0029
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0033 0.0086 0.0086
Onchocerca volvulus 0.0026 0.0029 0.0078
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0033 0.0086 0.0187
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0118 0.0716 0.3175
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.07 0.07
Schistosoma mansoni cathepsin D (A01 family) 0.0775 0.5627 0.5627
Echinococcus granulosus chromobox protein 1 0.0076 0.0406 0.0406
Echinococcus multilocularis beta tubulin 0.0034 0.0088 0.0088
Echinococcus granulosus expressed protein 0.0121 0.0737 0.0737
Giardia lamblia Cathepsin B precursor 0.0116 0.07 0.1914
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Toxoplasma gondii cathepsin CPC2 0.0116 0.07 0.1914
Echinococcus multilocularis conserved hypothetical protein 0.0033 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Echinococcus granulosus beta tubulin 0.0034 0.0088 0.0088
Schistosoma mansoni adenoreceptor 0.0069 0.0351 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0033 0.0086 0.0187
Brugia malayi aspartic protease BmAsp-2, identical 0.0062 0.0301 0.0301
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0076 0.0406 0.0406
Brugia malayi Proteasome A-type and B-type family protein 0.0055 0.0248 0.0248
Plasmodium falciparum serine repeat antigen 5 0.0116 0.07 0.3102
Schistosoma mansoni suppressor of cytokine signaling 0.0026 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1088
Onchocerca volvulus 0.0318 0.2214 1
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Brugia malayi RE15519p 0.0069 0.0351 0.0351
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0033 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0116 0.07 0.0682
Loa Loa (eye worm) ctsf protein 0.0318 0.2214 0.2214
Schistosoma mansoni 60S ribosomal protein L21 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Toxoplasma gondii transporter, cation channel family protein 0.0033 0.0086 0.0187
Loa Loa (eye worm) hypothetical protein 0.0076 0.0406 0.0406
Brugia malayi Tachykinin-like peptides receptor 99D 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus granulosus 7tm_1 domain containing protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Echinococcus multilocularis Chromo domain 0.0076 0.0406 0.0406
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0026 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.07 0.1914
Schistosoma mansoni peroxidasin 0.0023 0.0012 0.0012
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0116 0.07 0.07
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0069 0.0351 0.0351
Schistosoma mansoni GTPase activating protein 0.0026 0.0029 0.0029
Schistosoma mansoni tensin 0.0026 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Echinococcus granulosus tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0116 0.07 0.1914
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0116 0.07 0.07
Giardia lamblia Cathepsin L precursor 0.0116 0.07 0.1914
Giardia lamblia Cysteine protease 0.0116 0.07 0.1914
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0028 0.0043 0.0043
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0033 0.0086 0.0086
Plasmodium falciparum plasmepsin II 0.0263 0.18 0.8115
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Schistosoma mansoni cathepsin F (C01 family) 0.0318 0.2214 0.2214
Echinococcus multilocularis fmrfamide receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis sodium channel protein 0.0516 0.3696 0.3696
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0116 0.07 0.07
Schistosoma mansoni transient receptor potential channel 0.0033 0.0086 0.0086
Echinococcus granulosus neuropeptide Y receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis expressed protein 0.0121 0.0737 0.0737
Echinococcus multilocularis short transient receptor potential channel 6 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0026 0.0029 0.0029
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0116 0.07 0.3102
Echinococcus multilocularis dro:myosuppressin receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Toxoplasma gondii hypothetical protein 0.0033 0.0086 0.0187
Echinococcus multilocularis beta tubulin 0.0034 0.0088 0.0088
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0037 0.011 0.0091
Plasmodium vivax serine-repeat antigen (SERA) 0.0116 0.07 0.3102
Brugia malayi cation channel family protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis Tubulin beta 2C chain 0.0034 0.0088 0.0088
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0026 0.0032 0.0032
Echinococcus multilocularis NCK adaptor protein 0.0026 0.0029 0.0029
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0033 0.0086 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0069 0.0351 0.0351
Brugia malayi Dopamine receptor protein 1 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Echinococcus multilocularis ryanodine receptor 44f 0.0033 0.0086 0.0086
Giardia lamblia Cathepsin L-like protease 0.0116 0.07 0.1914
Echinococcus multilocularis transient receptor potential cation channel 0.0033 0.0086 0.0086
Echinococcus multilocularis SHC transforming protein 3 0.0227 0.1532 0.1532
Echinococcus granulosus transient receptor potential cation channel 0.0033 0.0086 0.0086
Echinococcus multilocularis two pore calcium channel protein 1 0.0033 0.0086 0.0086
Loa Loa (eye worm) beta-tubulin 0.0034 0.0088 0.0088
Brugia malayi SRC-1 0.0026 0.0032 0.0032
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0605 0.4356 0.4356
Brugia malayi Protein kinase domain containing protein 0.0026 0.0032 0.0032
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Echinococcus granulosus TRP transient receptor potential channel 0.0033 0.0086 0.0086
Loa Loa (eye worm) heterochromatin protein 1 0.0076 0.0406 0.0406
Brugia malayi Transient-receptor-potential like protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0312 0.2169 0.2169
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0024 0.002 0.002
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Echinococcus granulosus neuropeptide FF receptor 2 0.0069 0.0351 0.0351
Echinococcus multilocularis transient receptor potential gamma protein 0.0033 0.0086 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0115 0.0115
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0033 0.0086 0.0086
Plasmodium vivax tubulin beta chain, putative 0.0034 0.0088 0.0313
Brugia malayi Tubulin beta-1 chain 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0026 0.0032 0.0032
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0055 0.0248 0.0229
Loa Loa (eye worm) neuropeptide F receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0026 0.0029 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus granulosus tyrosine protein kinase Blk 0.0026 0.0032 0.0032
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0076 0.0406 0.0406
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Echinococcus granulosus g protein coupled receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0026 0.0029 0.0029
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Echinococcus granulosus cathepsin L cysteine proteinase 0.0318 0.2214 0.2214
Onchocerca volvulus 0.0147 0.0934 0.4186
Echinococcus multilocularis serotonin receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0026 0.0029 0.0029
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0024 0.002 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi fibroinase precursor 0.0116 0.07 0.07
Echinococcus granulosus SH2 domain containing protein 7 0.0026 0.0029 0.0029
Schistosoma mansoni opsin-like receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0318 0.2214 0.2214
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0517 0.0517
Trichomonas vaginalis tubulin epsilon chain, putative 0.0034 0.0088 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0116 0.07 0.1914
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0033 0.0086 0.0086
Echinococcus granulosus Tubulin beta 2C chain 0.0034 0.0088 0.0088
Loa Loa (eye worm) neuropeptide F receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis neuropeptide receptor 0.0069 0.0351 0.0351
Echinococcus multilocularis sodium leak channel non selective protein 0.0033 0.0086 0.0086
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0116 0.07 0.3102
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0069 0.0351 0.0351
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Onchocerca volvulus 0.0062 0.0301 0.1311
Schistosoma mansoni biogenic amine (5HT) receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0116 0.07 0.1914
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Brugia malayi G-protein coupled receptor 0.0069 0.0351 0.0351
Brugia malayi cathepsin Z-like cysteine proteinase 0.0116 0.07 0.07
Echinococcus multilocularis Tubulin beta 2C chain 0.0034 0.0088 0.0088
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0028 0.0043 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0069 0.0351 0.0351
Loa Loa (eye worm) proteasome subunit beta type 2 0.0024 0.002 0.002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.05 0.3576 0.3564
Echinococcus granulosus transient receptor potential gamma protein 0.0033 0.0086 0.0086
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0033 0.0086 0.0086
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0116 0.07 0.07
Echinococcus granulosus dro:myosuppressin receptor 0.0069 0.0351 0.0351
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Giardia lamblia Cathepsin B precursor 0.0116 0.07 0.1914
Loa Loa (eye worm) hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0116 0.07 0.1914
Echinococcus granulosus g protein coupled receptor 0.0069 0.0351 0.0351
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0028 0.0043 0.0064
Plasmodium falciparum cysteine proteinase falcipain 3 0.0318 0.2214 1
Entamoeba histolytica cysteine proteinase, putative 0.0116 0.07 0.3102
Echinococcus granulosus beta tubulin 0.0034 0.0088 0.0088
Brugia malayi ion channel NompC 0.0033 0.0086 0.0086
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0116 0.07 0.1914
Schistosoma mansoni voltage-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis neuropeptide Y receptor 0.0069 0.0351 0.0351
Entamoeba histolytica cysteine protease, putative 0.0116 0.07 0.3102
Echinococcus multilocularis neuropeptides capa receptor 0.0069 0.0351 0.0351
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Echinococcus multilocularis neuropeptide receptor 0.0069 0.0351 0.0351
Brugia malayi cathepsin L precursor 0.0116 0.07 0.07
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0026 0.0029 0.0078
Giardia lamblia Cysteine protease 0.0116 0.07 0.1914
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0069 0.0351 0.0351
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0033 0.0086 0.0086
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0086 0.0086
Echinococcus multilocularis muscleblind protein 0.0312 0.2169 0.2169
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor 0.0069 0.0351 0.0351
Toxoplasma gondii peptidylprolyl isomerase 0.0118 0.0716 0.1959
Schistosoma mansoni tubulin subunit beta 0.0034 0.0088 0.0088
Brugia malayi Serotonin receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) TK/FER protein kinase 0.0026 0.0032 0.0032
Brugia malayi STAT protein, DNA binding domain containing protein 0.0977 0.7139 0.7139
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0026 0.0029 0.0029
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0026 0.0029 0.0029
Plasmodium falciparum plasmepsin III 0.0062 0.0301 0.1282
Brugia malayi SET domain containing protein 0.0077 0.0412 0.0412
Echinococcus multilocularis potassium voltage gated channel protein 0.0033 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0116 0.07 0.1914
Brugia malayi protein-tyrosine kinase 0.0026 0.0032 0.0032
Leishmania major beta tubulin 0.0034 0.0088 0.0187
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0033 0.0086 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus granulosus two pore calcium channel protein 1 0.0033 0.0086 0.0086
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Brugia malayi Dopamine receptor protein 2 0.0069 0.0351 0.0351
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0069 0.0351 0.0351
Plasmodium vivax vivapain-1 0.0116 0.07 0.3102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0026 0.0032 0.0032
Loa Loa (eye worm) TYRA-2 protein 0.0069 0.0351 0.0351
Brugia malayi Animal haem peroxidase family protein 0.0023 0.0012 0.0012
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0026 0.0029 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.136 1 1
Giardia lamblia Encystation-specific protease 0.0116 0.07 0.1914
Echinococcus granulosus SH2 motif 0.0026 0.0029 0.0029
Brugia malayi Papain family cysteine protease containing protein 0.0116 0.07 0.07
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0033 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0023 0.0012 0.0012
Onchocerca volvulus 0.0069 0.0351 0.154
Onchocerca volvulus 0.0069 0.0351 0.154
Echinococcus granulosus orexin receptor type 2 0.0069 0.0351 0.0351
Loa Loa (eye worm) fibroinase 0.0318 0.2214 0.2214
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0069 0.0351 0.0351
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0318 0.2214 0.617
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0076 0.0406 0.0406
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0026 0.0029 0.0029
Echinococcus granulosus proteasome prosome macropain 0.0055 0.0248 0.0248
Brugia malayi follicle stimulating hormone receptor 0.0069 0.0351 0.0351
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus multilocularis serotonin receptor 0.0069 0.0351 0.0351
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0129 0.0801 0.0801
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0318 0.2214 0.617
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0026 0.0029 0.0029
Giardia lamblia Beta tubulin 0.0034 0.0088 0.0193
Echinococcus granulosus expressed conserved protein 0.0026 0.0029 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0351 0.0351
Brugia malayi Variant SH3 domain containing protein 0.0026 0.0029 0.0029
Brugia malayi voltage-dependent calcium channel 0.0033 0.0086 0.0086
Schistosoma mansoni cathepsin C 0.0116 0.07 0.07
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0026 0.0032 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0076 0.0406 0.1088
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0076 0.0406 0.1763
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0033 0.0086 0.0086
Schistosoma mansoni voltage-gated cation channel 0.0033 0.0086 0.0086
Echinococcus granulosus Chromo domain 0.0076 0.0406 0.0406
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0055 0.0248 0.0642
Schistosoma mansoni biogenic amine (5HT) receptor 0.0069 0.0351 0.0351
Brugia malayi hypothetical protein 0.0069 0.0351 0.0351
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0069 0.0351 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0076 0.0406 0.1088
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0116 0.07 0.07
Echinococcus granulosus voltage gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis chromobox protein 1 0.0076 0.0406 0.0406
Brugia malayi Cathepsin L-like cysteine proteinase 0.0318 0.2214 0.2214
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0033 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0026 0.0032 0.0032
Echinococcus multilocularis signal transduction protein lnk realted 0.0026 0.0029 0.0029
Echinococcus granulosus tubulin beta 1 chain 0.0034 0.0088 0.0088
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0069 0.0351 0.0351
Plasmodium falciparum serine repeat antigen 1 0.0116 0.07 0.3102
Schistosoma mansoni SH2A 0.0026 0.0029 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0116 0.07 0.1914
Plasmodium falciparum plasmepsin I 0.0263 0.18 0.8115
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0062 0.0301 0.0301
Leishmania major cathepsin L-like protease 0.0318 0.2214 0.5969
Echinococcus granulosus tubulin subunit beta 0.0034 0.0088 0.0088
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0033 0.0086 0.0086
Echinococcus granulosus biogenic amine 5HT receptor 0.0069 0.0351 0.0351
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0062 0.0301 0.0791
Brugia malayi Animal haem peroxidase family protein 0.0023 0.0012 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0069 0.0351 0.0351
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0033 0.0086 0.0086
Echinococcus granulosus potassium voltage gated channel protein 0.0033 0.0086 0.0086
Toxoplasma gondii beta-tubulin, putative 0.0034 0.0088 0.0193
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0026 0.0029 0.0029
Brugia malayi SH2 domain containing protein 0.0026 0.0032 0.0032

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 14.1 mg kg-1 Neuroleptic activity in po dosed STD-ddY mouse assessed as inhibition of spontaneous motor activity by measuring number of revolution of cage for 5 mins ChEMBL. 31476

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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