Detailed information for compound 2073172

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1295.65 | Formula: C60H102N12O15S2
  • H donors: 6 H acceptors: 10 LogP: 7.06 Rotable bonds: 54
    Rule of 5 violations (Lipinski): 3
  • SMILES: CCCCCC(=O)O[C@@H]1[C@@H](O[C@H]2O[C@H](Cn3nnc(c3)CNC(=S)NCCN)[C@H]([C@@H]([C@H]2OC(=O)CCCCC)OC(=O)CCCCC)OC(=O)CCCCC)O[C@@H]([C@H]([C@@H]1OC(=O)CCCCC)OC(=O)CCCCC)Cn1nnc(c1)CNC(=S)NCCN
  • InChi: 1S/C60H102N12O15S2/c1-7-13-19-25-45(73)81-51-43(39-71-37-41(67-69-71)35-65-59(88)63-33-31-61)79-57(55(85-49(77)29-23-17-11-5)53(51)83-47(75)27-21-15-9-3)87-58-56(86-50(78)30-24-18-12-6)54(84-48(76)28-22-16-10-4)52(82-46(74)26-20-14-8-2)44(80-58)40-72-38-42(68-70-72)36-66-60(89)64-34-32-62/h37-38,43-44,51-58H,7-36,39-40,61-62H2,1-6H3,(H2,63,65,88)(H2,64,66,89)/t43-,44-,51-,52-,53+,54+,55-,56+,57-,58-/m1/s1
  • InChiKey: KDCKBLTYLFMMIQ-VGDWLRJQSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus cathepsin L cysteine proteinase 0.0014 0.0003 0.0002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0018 0.0007 0.0009
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0018 0.0007 0.0007
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0008 0.0007
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0006 0.0008
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0068 0.0069 0.0092
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0077 0.008 0.0079
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0091 0.0122
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0013 0.0002 0.0001
Leishmania major telomerase reverse transcriptase, putative 0.0042 0.0038 0.005
Loa Loa (eye worm) carboxylesterase 0.0019 0.0009 0.0012
Loa Loa (eye worm) nuclear hormone receptor 0.0013 0.0002 0.0002
Schistosoma mansoni nuclear receptor 0.0013 0.0002 0.0001
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Loa Loa (eye worm) fibroinase 0.0014 0.0003 0.0003
Echinococcus granulosus survival motor neuron protein 1 0.0218 0.0252 0.0252
Leishmania major hypothetical protein, conserved 0.0033 0.0026 0.0035
Giardia lamblia Telomerase catalytic subunit 0.0042 0.0038 0.004
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0039 0.0053
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0012 0.0016
Toxoplasma gondii ABC1 family protein 0.0033 0.0026 0.0032
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0019 0.0009 0.0024
Echinococcus granulosus NADH ubiquinone oxidoreductase 42 kDa subunit 0.1431 0.1735 0.1734
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.001
Brugia malayi hypothetical protein 0.0015 0.0004 0.0005
Onchocerca volvulus 0.006 0.006 0.0082
Toxoplasma gondii thioredoxin reductase 0.0048 0.0045 0.0056
Schistosoma mansoni RAR-like nuclear receptor 0.0028 0.002 0.0019
Trichomonas vaginalis conserved hypothetical protein 0.2809 0.3418 0.8705
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0022 0.0027
Toxoplasma gondii RNA-directed DNA polymerase 0.0042 0.0038 0.0047
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0087 0.0092 0.0686
Mycobacterium tuberculosis Probable hydrolase 0.0033 0.0026 0.0026
Giardia lamblia Kinase, PLK 0.0068 0.0069 0.0079
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0042 0.0038 0.005
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.002 0.0019
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Loa Loa (eye worm) inositol-1 0.0064 0.0064 0.0089
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.006 0.006 0.0059
Leishmania major endonuclease/exonuclease protein-like protein 0.0018 0.0007 0.001
Mycobacterium ulcerans thymidylate kinase 0.104 0.1256 0.1444
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0002 0.0001
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0083 0.0088 0.0224
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0134 0.015 0.0149
Brugia malayi CXXC zinc finger family protein 0.0022 0.0012 0.0016
Echinococcus granulosus inositol monophosphatase 1 0.0064 0.0064 0.0064
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0239 0.0278 0.0371
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0007 0.0008
Brugia malayi 6-phosphofructokinase 0.0111 0.0122 0.0168
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0028 0.002 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0018 0.0007 0.001
Echinococcus granulosus ribonuclease H1 0.0381 0.0452 0.0451
Trichomonas vaginalis thymidine kinase, putative 0.3225 0.3926 1
Mycobacterium ulcerans DNA polymerase IV 0.0036 0.003 0.0028
Mycobacterium ulcerans thymidine phosphorylase 0.1909 0.2319 0.2672
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0025 0.0016 0.0016
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0014 0.0019
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0064 0.0064 0.0086
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0028 0.002 0.0027
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0122 0.0121
Trichomonas vaginalis thymidine kinase, putative 0.3225 0.3926 1
Brugia malayi intermediate filament protein 0.0081 0.0085 0.0117
Onchocerca volvulus 0.0013 0.0002 0.0002
Echinococcus multilocularis deoxyribonuclease 1 2 0.0018 0.0007 0.0007
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0028 0.002 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0033 0.0026 0.0035
Entamoeba histolytica Thymidylate kinase, putative 0.104 0.1256 0.3198
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0115 0.016
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0044
Trypanosoma cruzi ribonuclease H1, putative 0.0381 0.0452 0.0603
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0022 0.0027
Loa Loa (eye worm) hypothetical protein 0.008 0.0083 0.0115
Trichomonas vaginalis reverse transcriptases, putative 0.006 0.006 0.0152
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0013 0.0002 0.0002
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0087 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.001
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.006 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0018 0.0007 0.001
Brugia malayi Nuclear hormone receptor-like 1 0.0028 0.002 0.0027
Brugia malayi DNA polymerase family B containing protein 0.0069 0.007 0.0097
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0004 0.0004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0028 0.002 0.0019
Leishmania major cathepsin L-like protease 0.0014 0.0003 0.0003
Mycobacterium ulcerans hypothetical protein 0.0266 0.0311 0.0352
Schistosoma mansoni hypothetical protein 0.0073 0.0074 0.0074
Treponema pallidum exodeoxyribonuclease (exoA) 0.0087 0.0092 0.0686
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Onchocerca volvulus 0.0014 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0002 0.0002
Echinococcus granulosus histone lysine methyltransferase setb 0.0025 0.0016 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0239 0.0278 0.0371
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0006 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0014 0.0003 0.0006
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.0136 0.0152
Loa Loa (eye worm) beta-lactamase 0.0033 0.0026 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Brugia malayi DNA polymerase I family protein 0.0056 0.0054 0.0074
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0002 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.1431 0.1735 0.4418
Brugia malayi ecdysteroid receptor 0.0028 0.002 0.0027
Schistosoma mansoni inositol monophosphatase 0.0064 0.0064 0.0064
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.001
Entamoeba histolytica thymidine kinase, putative 0.3225 0.3926 1
Trypanosoma brucei DNA polymerase alpha catalytic subunit 0.0083 0.0088 0.0117
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0125 0.0124
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0122 0.0133
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0028 0.002 0.0019
Brugia malayi DNA polymerase alpha catalytic subunit 0.0117 0.0129 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0057 0.0058
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.002 0.0027
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0028 0.002 0.0019
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.6144 0.7492 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0077 0.008 0.0079
Schistosoma mansoni hypothetical protein 0.0599 0.0718 0.0717
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0064 0.0064 0.0086
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.003 0.003
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Echinococcus granulosus thymidylate synthase 0.5905 0.7201 0.7201
Leishmania major RNA-editing complex protein MP100, putative 0.0018 0.0007 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Echinococcus multilocularis para nitrobenzyl esterase 0.0019 0.0009 0.0009
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0028 0.002 0.0019
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0018 0.0007 0.0007
Leishmania major cathepsin L-like protease 0.0014 0.0003 0.0003
Schistosoma mansoni cpg binding protein 0.0023 0.0014 0.0013
Trypanosoma brucei thymidylate kinase, putative 0.104 0.1256 0.1676
Schistosoma mansoni thyroid hormone receptor 0.017 0.0193 0.0193
Brugia malayi reverse transcriptase 0.006 0.006 0.0082
Onchocerca volvulus 0.0033 0.0026 0.0036
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Brugia malayi RNase H family protein 0.0381 0.0452 0.0626
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0006 0.0008
Mycobacterium ulcerans hypothetical protein 0.0033 0.0026 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.003 0.003
Leishmania major trypanothione reductase 0.0048 0.0045 0.006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0125 0.0172
Mycobacterium tuberculosis Probable anthranilate phosphoribosyltransferase TrpD 0.0539 0.0644 0.074
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.006 0.006 0.0059
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0087 0.0092 0.0102
Leishmania major DNA polymerase kappa, putative 0.0036 0.003 0.004
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0122 0.0168
Echinococcus granulosus cathepsin l cysteine peptidase 0.0014 0.0003 0.0002
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0122 0.0162
Trypanosoma brucei trypanothione reductase 0.0048 0.0045 0.006
Brugia malayi hypothetical protein 0.006 0.006 0.0082
Brugia malayi Galactosyltransferase family protein 0.0035 0.0029 0.004
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0009 0.0009
Echinococcus multilocularis cpg binding protein 0.0023 0.0014 0.0013
Plasmodium falciparum LCCL domain-containing protein 0.0018 0.0008 0.0007
Entamoeba histolytica hypothetical protein 0.0033 0.0026 0.0067
Brugia malayi Intermediate filament tail domain containing protein 0.0081 0.0085 0.0117
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0018 0.0007 0.001
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Mycobacterium tuberculosis Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) 0.104 0.1256 0.1447
Leishmania major DNA polymerase delta catalytic subunit, putative 0.0163 0.0185 0.0247
Trypanosoma cruzi ribonuclease H1, putative 0.0381 0.0452 0.0603
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0028 0.002 0.0019
Brugia malayi hypothetical protein 0.0015 0.0004 0.0005
Plasmodium vivax glutathione reductase, putative 0.0048 0.0045 0.0056
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0171 0.0195 0.027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Brugia malayi Pre-SET motif family protein 0.0025 0.0016 0.0022
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.2809 0.3418 0.4562
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0027 0.0026
Schistosoma mansoni hypothetical protein 0.0044 0.004 0.004
Wolbachia endosymbiont of Brugia malayi thymidylate kinase 0.104 0.1256 1
Plasmodium vivax DNA polymerase zeta catalytic subunit, putative 0.0069 0.007 0.009
Echinococcus multilocularis GPCR, family 2 0.0034 0.0027 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0442 0.0525 0.0701
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0122 0.0309
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus multilocularis Metazoa galactosyltransferase 0.003 0.0022 0.0022
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0004 0.0005
Loa Loa (eye worm) CXXC zinc finger family protein 0.0022 0.0012 0.0016
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0034 0.0027 0.0036
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0122 0.0162
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0033 0.0026 0.0026
Loa Loa (eye worm) thymidylate synthase 0.5905 0.7201 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0014 0.0003 0.0002
Trypanosoma brucei DNA polymerase zeta catalytic subunit, putative 0.0069 0.007 0.0094
Brugia malayi hypothetical protein 0.0015 0.0004 0.0005
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.006 0.006 0.0059
Leishmania major hypothetical protein, conserved 0.0018 0.0007 0.001
Leishmania major DNA polymerase epsilon catalytic subunit, putative 0.0069 0.007 0.0094
Schistosoma mansoni hypothetical protein 0.0599 0.0718 0.0717
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0028 0.002 0.0027
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.5905 0.7201 0.8315
Onchocerca volvulus Serine\/threonine kinase homolog 0.0068 0.0069 0.0094
Echinococcus multilocularis dna polymerase eta 0.0036 0.003 0.003
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0038 0.0033 0.0044
Trypanosoma brucei DNA polymerase delta catalytic subunit, putative 0.0163 0.0185 0.0247
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Brugia malayi thymidylate synthase 0.5905 0.7201 1
Loa Loa (eye worm) hypothetical protein 0.0081 0.0085 0.0117
Entamoeba histolytica DNA polymerase alpha catalytic subunit, putative 0.0045 0.0041 0.0104
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0004 0.0003
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Brugia malayi hypothetical protein 0.0018 0.0008 0.001
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0018 0.0007 0.0018
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0018 0.0007 0.001
Mycobacterium ulcerans lipase LipD 0.0033 0.0026 0.0023
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0013 0.0002 0.0002
Leishmania major cytochrome p450-like protein 0.0017 0.0007 0.0009
Treponema pallidum hypothetical protein 0.0018 0.0007 0.0008
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0043
Brugia malayi Thioredoxin reductase 0.0048 0.0045 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0071 0.0073 0.0097
Onchocerca volvulus Cathepsin L homolog 0.0014 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0087 0.0092 0.0119
Brugia malayi beta-lactamase family protein 0.0033 0.0026 0.0036
Echinococcus granulosus geminin 0.0599 0.0718 0.0717
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0006 0.0016
Trichomonas vaginalis set domain proteins, putative 0.0195 0.0224 0.057
Plasmodium falciparum thymidylate kinase 0.104 0.1256 0.1673
Echinococcus granulosus Thymidine kinase 2 mitochondrial 0.8197 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0018 0.0007 0.0007
Echinococcus multilocularis neuroligin 0.0019 0.0009 0.0009
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0004 0.0001
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0018 0.0007 0.0007
Onchocerca volvulus DNA polymerase delta catalytic subunit homolog 0.0163 0.0185 0.0256
Echinococcus multilocularis thymidine kinase 0.8197 1 1
Schistosoma mansoni thymidylate kinase 0.104 0.1256 0.1255
Loa Loa (eye worm) RecQ helicase 0.0022 0.0012 0.0016
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Trypanosoma cruzi DNA polymerase kappa, putative 0.0036 0.003 0.004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0064 0.0064 0.0086
Onchocerca volvulus 0.5905 0.7201 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.0015 0.0014
Echinococcus granulosus nuclear receptor nhr 48 0.0013 0.0002 0.0001
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0018 0.0007 0.0018
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0408 0.0484 0.0646
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0008 0.0007
Plasmodium falciparum DNA polymerase alpha catalytic subunit A 0.0045 0.0041 0.0051
Leishmania major cathepsin L-like protease 0.0052 0.005 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0122 0.0309
Giardia lamblia DNA polymerase delta, catalytic subunit 0.0163 0.0185 0.0227
Trypanosoma brucei SLACS reverse transcriptase, putative 0.006 0.006 0.0079
Brugia malayi reverse transcriptase 0.006 0.006 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0027 0.0068
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0013 0.0002 0.0001
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0048 0.0044 0.0059
Schistosoma mansoni cpg binding protein 0.0022 0.0012 0.0012
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0022 0.013
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Trypanosoma brucei RNA helicase, putative 0.2845 0.3461 0.462
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0122 0.0121
Schistosoma mansoni retinoic acid receptor RXR 0.0028 0.002 0.0019
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.0288 0.0399
Giardia lamblia Deoxyguanosine kinase/deoxyadenosine kinase subunit, putative 0.1431 0.1735 0.22
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0009 0.0009
Echinococcus granulosus para nitrobenzyl esterase 0.0019 0.0009 0.0009
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Echinococcus granulosus Ribosomal protein L34a 0.0026 0.0018 0.0017
Onchocerca volvulus DNA polymerase epsilon catalytic subunit A homolog 0.0069 0.007 0.0097
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0022 0.0027
Plasmodium falciparum thioredoxin reductase 0.0017 0.0006 0.0005
Trypanosoma brucei unspecified product 0.0025 0.0016 0.0022
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Onchocerca volvulus Protein ultraspiracle homolog 0.0028 0.002 0.0027
Schistosoma mansoni phosphoglucomutase 0.0381 0.0452 0.0451
Echinococcus granulosus thymidine phosphorylase 0.1909 0.2319 0.2318
Trichomonas vaginalis DNA polymerase zeta catalytic subunit, putative 0.0163 0.0185 0.0471
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0006 0.0008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0087 0.0092 0.0099
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0038 0.0033 0.0083
Plasmodium falciparum DNA polymerase epsilon catalytic subunit A, putative 0.0038 0.0033 0.004
Schistosoma mansoni neuroligin 3 (S09 family) 0.0019 0.0009 0.0009
Trypanosoma brucei RNA editing exonuclease 2 0.0018 0.0007 0.001
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0007 0.0009
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Leishmania major ribonuclease H1, putative 0.0381 0.0452 0.0603
Echinococcus multilocularis dna polymerase kappa 0.0036 0.003 0.003
Schistosoma mansoni ap endonuclease 0.0087 0.0092 0.0091
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0018 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.006 0.0059
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0036 0.003 0.004
Schistosoma mansoni thymidylate kinase 0.104 0.1256 0.1255
Onchocerca volvulus 0.0195 0.0224 0.031
Schistosoma mansoni NADH-ubiquinone oxidoreductase 0.1431 0.1735 0.1734
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.006 0.006 0.0068
Loa Loa (eye worm) cysteine protease 0.0014 0.0003 0.0003
Brugia malayi conserved hypotetical protein 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Carboxylesterase LipT 0.0019 0.0009 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0014 0.0016
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.003 0.003
Mycobacterium ulcerans DNA polymerase IV 0.0036 0.003 0.0028
Echinococcus multilocularis lamin 0.0081 0.0085 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0013 0.0002 0.0001
Echinococcus multilocularis thymidylate kinase 0.104 0.1256 0.1255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Echinococcus multilocularis musashi 0.0081 0.0085 0.0084
Echinococcus granulosus DNA polymerase alpha catalytic subunit 0.0134 0.015 0.0149
Onchocerca volvulus 0.006 0.006 0.0082
Brugia malayi beta-lactamase family protein 0.0033 0.0026 0.0036
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0028 0.002 0.0027
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.0036 0.0048
Trypanosoma brucei DNA polymerase epsilon catalytic subunit, putative 0.0069 0.007 0.0094
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0064 0.0064 0.0083
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Brugia malayi Dihydrofolate reductase 0.041 0.0486 0.0675
Echinococcus granulosus lamin 0.0081 0.0085 0.0084
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0016 0.0016
Echinococcus granulosus traf and tnf receptor associated protein 0.0018 0.0007 0.0007
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0033 0.0026 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0028 0.002 0.0027
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0122 0.0309
Trichomonas vaginalis esterase, putative 0.0033 0.0026 0.0067
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0018 0.0007 0.0009
Echinococcus multilocularis traf and tnf receptor associated protein 0.0018 0.0007 0.0007
Schistosoma mansoni lamin 0.0081 0.0085 0.0084
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0013 0.0002 0.0001
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Loa Loa (eye worm) steroid hormone receptor 0.0028 0.002 0.0027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0028 0.002 0.0019
Trichomonas vaginalis thymidine kinase, putative 0.3225 0.3926 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0074 0.0103
Trypanosoma cruzi polo-like protein kinase, putative 0.0068 0.0069 0.0092
Onchocerca volvulus DNA polymerase alpha catalytic subunit homolog 0.0168 0.0191 0.0265
Echinococcus granulosus bloom syndrome protein 0.0022 0.0012 0.0012
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0006 0.0008
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0047 0.0043 0.0042
Schistosoma mansoni nocturnin 0.0018 0.0007 0.0007
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Toxoplasma gondii thymidylate kinase 0.104 0.1256 0.1673
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Plasmodium vivax DNA polymerase alpha, putative 0.0117 0.0129 0.0169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0034 0.0033
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0028 0.002 0.0027
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0026
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0058 0.0057 0.0062
Onchocerca volvulus Cathepsin L homolog 0.0014 0.0003 0.0003
Brugia malayi hypothetical protein 0.006 0.006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Loa Loa (eye worm) intermediate filament protein 0.0081 0.0085 0.0117
Loa Loa (eye worm) carboxylesterase 0.0114 0.0125 0.0172
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.5905 0.7201 0.831
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0028 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Brugia malayi isocitrate dehydrogenase 0.0015 0.0004 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0023 0.0014 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.1431 0.1735 0.4418
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0016 0.0022
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0064 0.0064 0.0067
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0014 0.0003 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0122 0.0309
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0045 0.0044
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0239 0.0278 0.0371
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0045 0.0044
Toxoplasma gondii isocitrate dehydrogenase 0.0015 0.0004 0.0001
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.041 0.0486 0.0558
Onchocerca volvulus 0.0014 0.0003 0.0003
Schistosoma mansoni nuclear receptor 0.0013 0.0002 0.0001
Brugia malayi hypothetical protein 0.0019 0.0009 0.0012
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0006 0.0008
Trichomonas vaginalis DNA polymerase II, putative 0.0083 0.0088 0.0224
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Schistosoma mansoni DNA polymerase eta 0.0036 0.003 0.003
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0018 0.0007 0.001
Toxoplasma gondii exonuclease III APE 0.0087 0.0092 0.0119
Brugia malayi follicle stimulating hormone receptor 0.0247 0.0288 0.0399
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0142 0.0159 0.0159
Trypanosoma brucei unspecified product 0.0442 0.0525 0.0701
Leishmania major cathepsin L-like protease 0.0052 0.005 0.0066
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0087 0.0092 0.0109
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0018 0.0007 0.0009
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0025 0.0016 0.0016
Echinococcus multilocularis thyroid hormone receptor alpha 0.017 0.0193 0.0193
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Echinococcus multilocularis Polycystic kidney disease protein 0.0018 0.0008 0.0007
Trypanosoma cruzi thymidine kinase, putative 0.3225 0.3926 0.5241
Giardia lamblia Deoxynucleoside kinase 0.6448 0.7864 1
Giardia lamblia DINP protein human, muc B family 0.0036 0.003 0.0031
Brugia malayi 6-phosphofructokinase 0.0111 0.0122 0.0168
Onchocerca volvulus 0.0044 0.004 0.0055
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0033 0.0026 0.0026
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.012 0.0109
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.6144 0.7492 1
Schistosoma mansoni survival motor neuron protein 0.0044 0.004 0.004
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Giardia lamblia Hypothetical protein 0.1431 0.1735 0.22
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0018 0.0007 0.0007
Trypanosoma cruzi mitochondrial protein 99, putative 0.0018 0.0007 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0015 0.0004 0.0001
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0122 0.011
Leishmania major hypothetical protein, conserved 0.0023 0.0014 0.0019
Onchocerca volvulus 0.0019 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Brugia malayi Carboxylesterase family protein 0.0114 0.0125 0.0172
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0122 0.0309
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0122 0.0136
Onchocerca volvulus 0.0019 0.0009 0.0012
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0018 0.0007 0.0018
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Schistosoma mansoni phosphoglucomutase 0.0381 0.0452 0.0451
Echinococcus multilocularis FTZ F1 alpha 0.0028 0.002 0.0019
Schistosoma mansoni kinase 0.0034 0.0028 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0028 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0004 0.0001
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0058 0.0057 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Trypanosoma brucei unspecified product 0.0025 0.0016 0.0022
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0002 0.0001
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.0136 0.0126
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0004 0.0005
Loa Loa (eye worm) ctsf protein 0.0014 0.0003 0.0003
Schistosoma mansoni DNA polymerase gamma 0.0056 0.0054 0.0053
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Brugia malayi Carboxylesterase family protein 0.0114 0.0125 0.0172
Mycobacterium tuberculosis Probable thymidine phosphorylase DeoA (tdrpase) (pyrimidine phosphorylase) 0.1909 0.2319 0.2675
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Trichomonas vaginalis DNA polymerase delta catalytic subunit, putative 0.0069 0.007 0.0178
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0007 0.0006
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0122 0.0121
Onchocerca volvulus 0.0081 0.0085 0.0117
Schistosoma mansoni lipoxygenase 0.0051 0.0048 0.0047
Mycobacterium ulcerans FAD-dependent thymidylate synthase 0.7099 0.8659 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0016 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0087 0.0092 0.0102
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Plasmodium falciparum glutathione reductase 0.0048 0.0045 0.0056
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0026 0.0067
Leishmania major DNA polymerase eta, putative 0.0036 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0016 0.0022
Echinococcus multilocularis lamin dm0 0.0081 0.0085 0.0084
Echinococcus granulosus dihydrofolate reductase 0.041 0.0486 0.0486
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.6144 0.7492 1
Schistosoma mansoni inositol monophosphatase 0.0064 0.0064 0.0064
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0006 0.0008
Echinococcus granulosus neuroligin 0.0019 0.0009 0.0009
Schistosoma mansoni polycystin 1-related 0.0018 0.0008 0.0007
Brugia malayi nuclear hormone receptor 0.0028 0.002 0.0027
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0142 0.0159 0.0159
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0027 0.0036
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0009
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0018 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0305 0.0358 0.0357
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0215 0.0249 0.0345
Mycobacterium tuberculosis Conserved protein 0.0033 0.0026 0.0026
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0064 0.0064 0.0086
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0018 0.0007 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0023 0.0014 0.0019
Mycobacterium ulcerans beta-lactamase 0.0033 0.0026 0.0023
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0018 0.0007 0.0018
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0039 0.0053
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0004 0.0002
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Brugia malayi Carboxylesterase family protein 0.0019 0.0009 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0023 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Loa Loa (eye worm) hypothetical protein 0.0038 0.0032 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0069 0.0068
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0028 0.002 0.0027
Echinococcus multilocularis nuclear receptor nhr 48 0.0013 0.0002 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus granulosus RNA directed DNA polymerase 0.006 0.006 0.0059
Echinococcus multilocularis ribonuclease H1 0.0381 0.0452 0.0451
Trichomonas vaginalis inositol monophosphatase, putative 0.0064 0.0064 0.0164
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0057 0.0056
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0057 0.0058
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Conserved protein 0.0033 0.0026 0.0026
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0045 0.006
Giardia lamblia Reverse transcriptase/endonuclease 0.006 0.006 0.0068
Brugia malayi RNase H family protein 0.0381 0.0452 0.0626
Entamoeba histolytica hypothetical protein 0.0033 0.0026 0.0067
Echinococcus granulosus KRAB A domain containing protein 0.006 0.006 0.0059
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0004 0.0005
Mycobacterium tuberculosis Conserved protein 0.0033 0.0026 0.0026
Onchocerca volvulus 0.0033 0.0026 0.0036
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0068 0.0069 0.0068
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0064 0.0064 0.0164
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0087 0.0092 0.0119
Onchocerca volvulus 0.0014 0.0003 0.0003
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0018 0.0007 0.0006
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0008
Loa Loa (eye worm) DR-78 0.0013 0.0002 0.0002
Schistosoma mansoni synaptojanin 0.0018 0.0007 0.0007
Trypanosoma brucei thymidylate kinase, putative 0.104 0.1256 0.1676
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0028 0.002 0.0027
Plasmodium falciparum telomerase reverse transcriptase 0.0042 0.0038 0.0047
Toxoplasma gondii histone lysine methyltransferase SET1 0.0042 0.0037 0.0046
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.006 0.006 0.0059
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0012 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0028 0.002 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.008 0.0079
Echinococcus granulosus neutral sphingomyelinase 0.0018 0.0007 0.0007
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0044 0.004 0.0055
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.012 0.0135
Onchocerca volvulus 0.0019 0.0009 0.0012
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0018 0.0007 0.0006
Onchocerca volvulus 0.0014 0.0003 0.0003
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0122 0.0121
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0006 0.0005
Brugia malayi nuclear receptor RXR 0.0015 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Echinococcus multilocularis transfer RNA-Ile 0.8197 1 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0033 0.0026 0.0026
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0002 0.0001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0004 0.0003
Echinococcus granulosus Metazoa galactosyltransferase 0.0035 0.0029 0.0029
Leishmania major thymidylate kinase-like protein 0.104 0.1256 0.1676
Trypanosoma cruzi DNA polymerase kappa, putative 0.0036 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Brugia malayi Carboxylesterase family protein 0.0019 0.0009 0.0012
Brugia malayi glutathione reductase 0.0048 0.0045 0.0061
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0005
Schistosoma mansoni hypothetical protein 0.2845 0.3461 0.3461
Trypanosoma cruzi thymidylate kinase, putative 0.104 0.1256 0.1676
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0028 0.002 0.0019
Mycobacterium ulcerans carboxylesterase, LipT 0.0019 0.0009 0.0003
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0018 0.0007 0.0018
Brugia malayi hypothetical protein 0.0218 0.0252 0.035
Onchocerca volvulus Cathepsin F homolog 0.0014 0.0003 0.0003
Trypanosoma brucei unspecified product 0.0036 0.003 0.004
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0068 0.0069 0.0094
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0006 0.0005
Schistosoma mansoni DNA polymerase delta catalytic subunit 0.0163 0.0185 0.0184
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0036 0.003 0.0031
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0058 0.0057 0.0076
Schistosoma mansoni BC026374 protein (S09 family) 0.0019 0.0009 0.0009
Echinococcus multilocularis Ribosomal protein L34a 0.0026 0.0018 0.0017
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0022 0.0027
Echinococcus multilocularis DNA polymerase delta catalytic subunit 0.0163 0.0185 0.0184
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0004 0.0005
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Loa Loa (eye worm) acetylcholinesterase 1 0.0114 0.0125 0.0172
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.1431 0.1735 0.4418
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Plasmodium falciparum DNA polymerase delta catalytic subunit 0.0163 0.0185 0.0244
Loa Loa (eye worm) carboxylesterase 0.0019 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Trypanosoma brucei telomerase reverse transcriptase 0.0042 0.0038 0.005
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0003 0.0003
Onchocerca volvulus DNA polymerase homolog 0.0069 0.007 0.0097
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0033 0.0026 0.0036
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0018 0.0007 0.0007
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0087 0.0092 0.0123
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0069 0.007 0.0094
Echinococcus multilocularis acetylcholinesterase 0.0114 0.0125 0.0124
Schistosoma mansoni cpg binding protein 0.0023 0.0014 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.005 0.0066
Trichomonas vaginalis thymidylate kinase, putative 0.104 0.1256 0.3198
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0087 0.0092 0.0123
Echinococcus granulosus DNA polymerase delta catalytic subunit 0.0163 0.0185 0.0184
Giardia lamblia Inositol 5-phosphatase 4 0.0018 0.0007 0.0001
Brugia malayi hypothetical protein 0.0023 0.0014 0.0019
Echinococcus granulosus FTZ F1 alpha 0.0028 0.002 0.0019
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0087 0.0092 0.0234
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0077 0.008 0.0079
Loa Loa (eye worm) cytochrome P450 family protein 0.0017 0.0007 0.0008
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0004 0.0003
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0004 0.0003
Loa Loa (eye worm) hypothetical protein 0.0036 0.003 0.0041
Loa Loa (eye worm) thymidylate kinase 0.104 0.1256 0.1743
Echinococcus multilocularis ecdysone induced protein 78C 0.0028 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0036
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0064 0.0064 0.0164
Schistosoma mansoni phosphoglucomutase 0.0381 0.0452 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0026 0.0067
Brugia malayi RNase H family protein 0.0381 0.0452 0.0626
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0003 0.0003
Trypanosoma cruzi thymidine kinase, putative 0.3225 0.3926 0.5241
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0071 0.0073 0.0097
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Echinococcus granulosus thymidylate kinase 0.104 0.1256 0.1255
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0018 0.0007 0.001
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0006 0.0005
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0505 0.0603 0.0804
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0006 0.0003
Brugia malayi nuclear receptor NHR-67 0.0013 0.0002 0.0002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0002 0.0002
Loa Loa (eye worm) CYP4Cod1 0.0017 0.0007 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0054 0.0052 0.0072
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Brugia malayi Inositol-1 0.0064 0.0064 0.0089
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.003 0.004
Trypanosoma cruzi cytochrome P450, putative 0.0017 0.0007 0.0009
Treponema pallidum ribonuclease H (rnhA) 0.0381 0.0452 0.3564
Loa Loa (eye worm) nuclear receptor NHR-67 0.0013 0.0002 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0057 0.0058
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Brugia malayi nuclear receptor NHR-88 0.0013 0.0002 0.0002
Onchocerca volvulus 0.0025 0.0016 0.0022
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.0136 0.0152
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0442 0.0525 0.0701
Brugia malayi Zinc knuckle family protein 0.006 0.006 0.0082
Onchocerca volvulus 0.0028 0.002 0.0027
Toxoplasma gondii DNA polymerase (pol2) superfamily protein 0.0117 0.0129 0.0169
Schistosoma mansoni loxhd1 0.0018 0.0008 0.0007
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.1431 0.1735 0.4418
Schistosoma mansoni intermediate filament proteins 0.0081 0.0085 0.0084
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0039 0.0034 0.0046
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0006
Plasmodium falciparum DNA polymerase zeta catalytic subunit, putative 0.0031 0.0023 0.0028
Schistosoma mansoni neutral sphingomyelinase 0.0018 0.0007 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.008 0.0079
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Brugia malayi nuclear receptor NHR-88 0.0028 0.002 0.0027
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Schistosoma mansoni beta-14-galactosyltransferase 0.0035 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.1431 0.1735 0.4418
Echinococcus multilocularis inositol monophosphatase 1 0.0064 0.0064 0.0064
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Trichomonas vaginalis ap endonuclease, putative 0.0087 0.0092 0.0234
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0008 0.0007
Onchocerca volvulus Putative neutral sphingomyelinase 0.0018 0.0007 0.0009
Echinococcus granulosus intermediate filament protein 0.0081 0.0085 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Leishmania major mitochondrial DNA polymerase beta 0.0505 0.0603 0.0804
Brugia malayi Doublecortin family protein 0.0018 0.0008 0.001
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2001 0.243 0.243
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0122 0.0168
Schistosoma mansoni lipoxygenase 0.0018 0.0008 0.0007
Mycobacterium tuberculosis Hypothetical protein 0.2809 0.3418 0.3945
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114 0.0125 0.0124
Loa Loa (eye worm) MH2 domain-containing protein 0.0054 0.0052 0.0072
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.006 0.006 0.0152
Giardia lamblia hypothetical protein 0.0018 0.0007 0.0001
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0018 0.0007 0.0018
Echinococcus granulosus lamin dm0 0.0081 0.0085 0.0084
Schistosoma mansoni DNA polymerase alpha catalytic subunit 0.0034 0.0027 0.0027
Trypanosoma brucei PAB1-binding protein , putative 0.0023 0.0014 0.0019
Trypanosoma brucei thymidine kinase 0.3225 0.3926 0.5241
Brugia malayi DNA polymerase family B, exonuclease domain containing protein 0.0069 0.007 0.0097
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.012 0.0135
Toxoplasma gondii DNA polymerase 0.0163 0.0185 0.0244
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0122 0.0168
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0018 0.0007 0.0009
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0028 0.002 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0028 0.002 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0005
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0057 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0015 0.0004 0.0003
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0045 0.0056
Echinococcus multilocularis cathepsin L cysteine protease 0.0014 0.0003 0.0002
Echinococcus multilocularis dna polymerase epsilon catalytic subunit a 0.0069 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Brugia malayi phosphofructokinase 0.0111 0.0122 0.0168
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0019 0.0009 0.0007
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0003 0.0006
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0115 0.016
Trypanosoma cruzi DNA polymerase zeta catalytic subunit, putative 0.0031 0.0023 0.0031
Brugia malayi nuclear hormone receptor family member odr-7 0.0013 0.0002 0.0002
Brugia malayi steroid hormone receptor 0.0028 0.002 0.0027
Loa Loa (eye worm) dihydrofolate reductase 0.041 0.0486 0.0675
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0027 0.0026
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0014 0.0003 0.0002
Leishmania major hypothetical protein, conserved 0.0408 0.0484 0.0646
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0071 0.0073 0.0097
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.1431 0.1735 0.4418
Toxoplasma gondii DNA polymerase family B protein 0.0069 0.007 0.009
Trichomonas vaginalis ap endonuclease, putative 0.0087 0.0092 0.0234
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.1431 0.1735 0.4418
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0505 0.0603 0.0804
Echinococcus granulosus dna polymerase epsilon catalytic subunit a 0.0069 0.007 0.007
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0028 0.002 0.0027
Echinococcus granulosus thymidine kinase 0.8197 1 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0028 0.002 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus multilocularis NADH ubiquinone oxidoreductase 42 kDa subunit 0.1431 0.1735 0.1734
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.002 0.0027
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0071 0.0073 0.0097
Leishmania major DNA polymerase I alpha catalytic subunit, putative 0.0083 0.0088 0.0117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Trypanosoma cruzi UMP-CMP kinase, mitochondrial, putative 0.0408 0.0484 0.0646
Echinococcus multilocularis neutral sphingomyelinase 0.0018 0.0007 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0028 0.002 0.0027
Loa Loa (eye worm) doublecortin family protein 0.0018 0.0008 0.001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Brugia malayi hypothetical protein 0.2809 0.3418 0.4747
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0018 0.0007 0.0006
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.003 0.004
Echinococcus multilocularis cysteine protease 0.0014 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0218 0.0252 0.035
Brugia malayi nuclear hormone receptor family member nhr-6 0.0013 0.0002 0.0002
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0006 0.0005
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0068 0.0069 0.0068
Entamoeba histolytica hypothetical protein 0.0033 0.0026 0.0067
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0009
Schistosoma mansoni thyroid hormone receptor 0.017 0.0193 0.0193
Trichomonas vaginalis reverse transcriptases, putative 0.006 0.006 0.0152
Echinococcus multilocularis RUN 0.0018 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0022
Echinococcus granulosus dna polymerase eta 0.0036 0.003 0.003
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.0136 0.0152
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.003 0.003
Mycobacterium ulcerans anthranilate phosphoribosyltransferase 0.0539 0.0644 0.0737
Brugia malayi hypothetical protein 0.0013 0.0002 0.0002
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0018 0.0007 0.0018
Toxoplasma gondii ribonuclease HI protein 0.0381 0.0452 0.06
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0022 0.0027
Mycobacterium ulcerans thymidylate synthase 0.5905 0.7201 0.8314
Brugia malayi Carboxylesterase family protein 0.0019 0.0009 0.0012
Mycobacterium tuberculosis Probable lipase LipD 0.0033 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0027 0.0068
Schistosoma mansoni cript-related 0.0018 0.0007 0.0007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.003 0.0077
Echinococcus multilocularis cysteine protease 0.0014 0.0003 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Leishmania major pantothenate kinase subunit, putative 0.0018 0.0007 0.001
Leishmania major cysteine peptidase A (CPA) 0.0014 0.0003 0.0003
Echinococcus granulosus DNA polymerase subunit gamma 0.0056 0.0054 0.0053
Trypanosoma cruzi DNA polymerase I alpha catalytic subunit, putative 0.0083 0.0088 0.0117
Echinococcus granulosus synaptojanin 1 0.0018 0.0007 0.0007
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0028 0.002 0.0019
Brugia malayi orphan nuclear receptor NR2E1 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.012 0.0135
Plasmodium vivax exodeoxyribonuclease III, putative 0.0018 0.0007 0.0006
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0018 0.0007 0.0018
Loa Loa (eye worm) hypothetical protein 0.0106 0.0115 0.016
Echinococcus multilocularis thymidine kinase 0.8197 1 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0033 0.0026 0.0026
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0018 0.0007 0.0018
Onchocerca volvulus 0.0022 0.0012 0.0016
Onchocerca volvulus 0.0033 0.0026 0.0036
Brugia malayi Deoxynucleoside kinase family protein 0.1431 0.1735 0.2408
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0015 0.0004 0.0003
Plasmodium falciparum glutathione reductase 0.0017 0.0006 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0028 0.002 0.0019
Leishmania major cathepsin L-like protease 0.0052 0.005 0.0066
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0052 0.005 0.0066
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0003 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0028 0.002 0.0027
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0026 0.0026
Trichomonas vaginalis Phospholipase C precursor, putative 0.0018 0.0007 0.0018
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0008 0.0007
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0018 0.0007 0.0009
Echinococcus granulosus DNA polymerase zeta catalytic subunit 0.0069 0.007 0.007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0087 0.0092 0.0091
Brugia malayi hypothetical protein 0.0033 0.0026 0.0036
Schistosoma mansoni lamin 0.0081 0.0085 0.0084
Trypanosoma cruzi telomerase reverse transcriptase, putative 0.0042 0.0038 0.005
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.003 0.0041
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0006 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0009
Echinococcus multilocularis thymidylate synthase 0.5905 0.7201 0.7201
Schistosoma mansoni hypothetical protein 0.0018 0.0007 0.0007
Brugia malayi serine/threonine-protein kinase plk-2 0.0068 0.0069 0.0094
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0018 0.0007 0.001
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0019 0.0009 0.0009
Trypanosoma cruzi polo-like protein kinase, putative 0.0068 0.0069 0.0092
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0018 0.0007 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.041 0.0486 0.0555
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0004 0.0003
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Echinococcus granulosus Polycystic kidney disease protein 0.0018 0.0008 0.0007
Brugia malayi Cytochrome P450 family protein 0.0017 0.0007 0.0008
Brugia malayi hypothetical protein 0.0018 0.0008 0.001
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0122 0.0309
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0009 0.0009
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0018 0.0007 0.0009
Schistosoma mansoni protein kinase 0.006 0.006 0.0059
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0004 0.0003
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0028 0.002 0.0019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0027 0.0036
Loa Loa (eye worm) hypothetical protein 0.0056 0.0054 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0022 0.0057
Schistosoma mansoni hypothetical protein 0.0033 0.0026 0.0026
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0018 0.0007 0.0006
Plasmodium falciparum thioredoxin reductase 0.0048 0.0045 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.1431 0.1735 0.4418
Trypanosoma brucei DNA polymerase IV, putative 0.0036 0.003 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0009
Schistosoma mansoni hypothetical protein 0.104 0.1256 0.1255
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0022 0.0021
Trypanosoma brucei ingi protein (ORF1) 0.0442 0.0525 0.0701
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.003 0.004
Brugia malayi Carboxylesterase family protein 0.0019 0.0009 0.0012
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0125 0.0138 0.0184
Leishmania major cathepsin L-like protease 0.0014 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Schistosoma mansoni cathepsin F (C01 family) 0.0014 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0059
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0045 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.002 0.0027
Mycobacterium leprae probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) 0.104 0.1256 0.1424
Trypanosoma cruzi DNA polymerase kappa, putative 0.0036 0.003 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.006 0.006 0.0079
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0022 0.0027
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.003 0.0041
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0028 0.002 0.0027
Giardia lamblia Hypothetical protein 0.1431 0.1735 0.22
Trypanosoma brucei polo-like protein kinase 0.0068 0.0069 0.0092
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0505 0.0603 0.0804
Loa Loa (eye worm) hypothetical protein 0.0114 0.0125 0.0172
Schistosoma mansoni gliotactin 0.0019 0.0009 0.0009
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0022 0.013
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0036 0.003 0.0077
Echinococcus granulosus carboxylesterase 5A 0.0114 0.0125 0.0124
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0015 0.0004 0.0005
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Possible maturase 0.006 0.006 0.0065
Schistosoma mansoni DNA polymerase zeta catalytic subunit 0.0069 0.007 0.007
Schistosoma mansoni rab6-interacting 0.0018 0.0008 0.0007
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0034 0.0033
Brugia malayi ecdysone receptor 0.0013 0.0002 0.0002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0051 0.0048 0.0047
Entamoeba histolytica cysteine protease, putative 0.0014 0.0003 0.0006
Onchocerca volvulus 0.0018 0.0008 0.001
Onchocerca volvulus 0.0019 0.0009 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Mycobacterium tuberculosis Probable exported protein 0.0018 0.0007 0.0004
Echinococcus multilocularis synaptojanin 1 0.0018 0.0007 0.0007
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.012 0.0135
Schistosoma mansoni rab6-interacting 0.0018 0.0008 0.0007
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0003 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0004 0.0005
Echinococcus multilocularis dihydrofolate reductase 0.041 0.0486 0.0486
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0004 0.0005
Giardia lamblia CDC8 0.104 0.1256 0.159
Trypanosoma brucei ribonuclease H1 0.0381 0.0452 0.0603
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0019 0.0009 0.0009
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0074 0.0103
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Onchocerca volvulus 0.0018 0.0008 0.001
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0028 0.002 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0077 0.008 0.0079
Leishmania major dihydrofolate reductase-thymidylate synthase 0.6144 0.7492 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Onchocerca volvulus 0.0018 0.0007 0.0009
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0015 0.0004 0.0003
Schistosoma mansoni ap endonuclease 0.0087 0.0092 0.0091
Echinococcus granulosus cathepsin l1 0.0014 0.0003 0.0002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0028 0.002 0.0019
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0077 0.008 0.0079
Trypanosoma cruzi thymidylate kinase, putative 0.104 0.1256 0.1676
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0018 0.0007 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Onchocerca volvulus 0.0018 0.0007 0.0009
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0077 0.008 0.011
Trypanosoma cruzi DNA polymerase epsilon catalytic subunit, putative 0.0069 0.007 0.0094
Leishmania major hypothetical protein, conserved 0.0018 0.0007 0.001
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0027 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0028 0.002 0.0027
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0018 0.0007 0.0009
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0022 0.0057
Trichomonas vaginalis DNA polymerase alpha catalytic subunit, putative 0.0069 0.007 0.0178
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.041 0.0486 0.0533
Entamoeba histolytica DNA polymerase zeta catalytic subunit, putative 0.0031 0.0023 0.0059
Onchocerca volvulus 0.0019 0.0009 0.0012
Schistosoma mansoni thymidine kinase 0.8197 1 1
Echinococcus granulosus cpg binding protein 0.0023 0.0014 0.0013
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0018 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0023 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0033 0.0026 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0077 0.008 0.011
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.006 0.006 0.0059
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0006 0.0008
Loa Loa (eye worm) DNA polymerase epsilon catalytic subunit 0.0031 0.0023 0.0032
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.006 0.006 0.0068
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0064 0.0064 0.0164
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0006
Chlamydia trachomatis thymidylate kinase 0.104 0.1256 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.012 0.0135
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0007 0.0006
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0015 0.0004 0.0003
Trypanosoma cruzi DNA polymerase delta catalytic subunit, putative 0.0163 0.0185 0.0247
Schistosoma mansoni synaptojanin 0.0018 0.0007 0.0007
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Brugia malayi Pao retrotransposon peptidase family protein 0.006 0.006 0.0082
Onchocerca volvulus 0.0014 0.0003 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0023 0.0014 0.0016
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0212 0.0245 0.0279
Schistosoma mansoni hypothetical protein 0.006 0.006 0.0059
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Trichomonas vaginalis spcc417.12 protein, putative 0.0019 0.0009 0.0024
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0033 0.0026 0.0026
Trichomonas vaginalis D-aminoacylase, putative 0.0033 0.0026 0.0067
Plasmodium vivax telomerase reverse transcriptase, putative 0.0042 0.0038 0.0047
Brugia malayi Telomerase reverse transcriptase 0.0113 0.0123 0.0171
Brugia malayi Zinc knuckle family protein 0.006 0.006 0.0082
Trypanosoma brucei cytochrome P450, putative 0.0017 0.0007 0.0009
Leishmania major cathepsin L-like protease 0.0014 0.0003 0.0003
Brugia malayi exodeoxyribonuclease III family protein 0.0087 0.0092 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Echinococcus granulosus acetylcholinesterase 0.0114 0.0125 0.0124
Brugia malayi dihydrofolate reductase family protein 0.041 0.0486 0.0675
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0007 0.001
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0019 0.0009 0.0009
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0018 0.0007 0.0007
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0058 0.0056 0.0035
Echinococcus multilocularis DNA polymerase alpha catalytic subunit 0.0134 0.015 0.0149
Brugia malayi hypothetical protein 0.006 0.006 0.0082
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0018 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0148 0.0167 0.0167
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.0014 0.0003 0.0003
Loa Loa (eye worm) DNA-directed DNA polymerase III 0.0163 0.0185 0.0256
Entamoeba histolytica hypothetical protein 0.1431 0.1735 0.4418
Echinococcus multilocularis thymidine phosphorylase 0.1909 0.2319 0.2318
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0018 0.0007 0.001
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYX (TS) (TSase) 0.7099 0.8659 1
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0026
Loa Loa (eye worm) deoxynucleoside kinase 0.1431 0.1735 0.2408
Echinococcus multilocularis geminin 0.0599 0.0718 0.0717
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0087 0.0092 0.0123
Echinococcus multilocularis RNA directed DNA polymerase 0.006 0.006 0.0059
Echinococcus granulosus ecdysone induced protein 78C 0.0028 0.002 0.0019
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0028 0.002 0.0019
Chlamydia trachomatis dihydrofolate reductase 0.041 0.0486 0.3843
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0028 0.002 0.0019
Schistosoma mansoni DNA polymerase epsilon catalytic subunit 0.0069 0.007 0.007
Brugia malayi DNA polymerase delta catalytic subunit 0.0163 0.0185 0.0256
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0004 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.0218 0.0252 0.0252
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Onchocerca volvulus Putative thymidylate kinase 0.104 0.1256 0.1743
Schistosoma mansoni hypothetical protein 0.0034 0.0027 0.0026
Trichomonas vaginalis ribonuclease H1, putative 0.0381 0.0452 0.115
Toxoplasma gondii hypothetical protein 0.0081 0.0085 0.011
Echinococcus granulosus acetylcholinesterase 0.0114 0.0125 0.0124
Toxoplasma gondii aldehyde dehydrogenase 0.0058 0.0057 0.0072
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0022 0.0027
Mycobacterium tuberculosis Probable reductase 0.011 0.012 0.0135
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0002 0.0002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0087 0.0092 0.0091
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0064 0.0064 0.0465
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.006 0.006 0.0068
Plasmodium vivax hypothetical protein, conserved 0.0033 0.0026 0.0032
Onchocerca volvulus Bile acid receptor homolog 0.0028 0.002 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0026 0.0035
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0005
Plasmodium vivax DNA polymerase epsilon, catalytic subunit a, putative 0.0069 0.007 0.009
Schistosoma mansoni carbon catabolite repressor protein 0.0018 0.0007 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0033 0.0026 0.0026
Onchocerca volvulus 0.0014 0.0003 0.0003
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0012 0.0012
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.0381 0.0452 0.3564
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0026 0.0035
Trypanosoma cruzi DNA polymerase kappa, putative 0.0036 0.003 0.004
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0012 0.0032
Giardia lamblia DNA polymerase alpha subunit A 0.0096 0.0103 0.0123
Trypanosoma brucei DNA polymerase kappa, putative 0.0036 0.003 0.004
Brugia malayi beta-lactamase 0.0033 0.0026 0.0036
Schistosoma mansoni acetylcholinesterase 0.0019 0.0009 0.0009
Brugia malayi hypothetical protein 0.006 0.006 0.0082
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.5905 0.7201 0.7201
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus granulosus BC026374 protein S09 family 0.0019 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0018 0.0008 0.0007
Schistosoma mansoni coup transcription factor 0.0028 0.002 0.0019
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.6144 0.7492 1
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.005 0.0066
Leishmania major thymidine kinase, putative 0.3225 0.3926 0.5241
Loa Loa (eye worm) glutathione reductase 0.0048 0.0045 0.0061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0025 0.0016 0.0016
Entamoeba histolytica serine/threonine protein kinase, putative 0.0068 0.0069 0.0175
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0028 0.002 0.0027
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0122 0.0923
Trichomonas vaginalis thymidylate kinase, putative 0.104 0.1256 0.3198
Echinococcus granulosus GPCR family 2 0.0034 0.0027 0.0026
Mycobacterium tuberculosis Conserved hypothetical protein 0.0266 0.0311 0.0355
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Trypanosoma cruzi cruzipain precursor, putative 0.0052 0.005 0.0066
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0005
Schistosoma mansoni beta-14-galactosyltransferase 0.0035 0.0029 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0002 0.0001
Brugia malayi Pre-SET motif family protein 0.0171 0.0195 0.027
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0025 0.0016 0.0018
Echinococcus granulosus dna polymerase kappa 0.0036 0.003 0.003
Brugia malayi MH2 domain containing protein 0.0054 0.0052 0.0072
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.006 0.006 0.0152
Trypanosoma cruzi cysteine peptidase, putative 0.0052 0.005 0.0066
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.006 0.006 0.0068
Brugia malayi nuclear receptor RXR 0.0013 0.0002 0.0002
Mycobacterium tuberculosis Probable lipase LipE 0.0033 0.0026 0.0026
Entamoeba histolytica deoxyuridine 5-triphosphate nucleotidohydrolase domain containing protein 0.1431 0.1735 0.4418
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0028 0.002 0.0027
Plasmodium vivax multidomain scavenger receptor, putative 0.0018 0.0008 0.0007
Brugia malayi Cytochrome P450 family protein 0.0017 0.0007 0.0008
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0022 0.013
Plasmodium vivax ataxin-2 like protein, putative 0.0023 0.0014 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.003 0.0031
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0002
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0115 0.016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0018 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Echinococcus multilocularis DNA polymerase zeta catalytic subunit 0.0069 0.007 0.007
Trypanosoma cruzi mitochondrial protein 99, putative 0.0018 0.0007 0.001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0013 0.0002 0.0001
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0018 0.0007 0.0009
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0033 0.0026 0.0036
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0058 0.0057 0.0056
Loa Loa (eye worm) hypothetical protein 0.0038 0.0033 0.0044
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.003 0.0041
Onchocerca volvulus Ribonuclease H1 homolog 0.0381 0.0452 0.0626
Toxoplasma gondii LsmAD domain-containing protein 0.0023 0.0014 0.0016
Mycobacterium tuberculosis Probable thymidylate synthase ThyX (ts) (TSase) 0.7099 0.8659 1
Treponema pallidum thymidylate kinase (tmk) 0.104 0.1256 1
Plasmodium vivax DNA polymerase delta catalytic subunit, putative 0.0163 0.0185 0.0244
Brugia malayi reverse transcriptase 0.006 0.006 0.0082
Loa Loa (eye worm) hypothetical protein 0.0028 0.002 0.0027
Entamoeba histolytica hypothetical protein 0.0033 0.0026 0.0067
Giardia lamblia Ribonuclease H 0.0381 0.0452 0.0567
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.003 0.004
Mycobacterium ulcerans esterase/lipase LipP 0.0033 0.0026 0.0023
Echinococcus multilocularis hypothetical protein 0.0056 0.0054 0.0053
Toxoplasma gondii DNA polymerase family B protein 0.0031 0.0023 0.0028
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0069 0.0175
Brugia malayi tailless protein 0.0013 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Schistosoma mansoni scy1(yeast) protein kinase-like 0.006 0.006 0.0059
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0033 0.0026 0.0023
Giardia lamblia DNA polymerase epsilon, catalytic subunit 0.0069 0.007 0.0081
Giardia lamblia Thymidine kinase 0.3225 0.3926 0.4989
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.6144 0.7492 1
Plasmodium vivax SET domain protein, putative 0.0025 0.0016 0.0018
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0018 0.0007 0.0006
Trypanosoma brucei ingi protein (ORF1) 0.0442 0.0525 0.0701
Loa Loa (eye worm) hypothetical protein 0.0015 0.0004 0.0005
Schistosoma mansoni nuclear hormone receptor 0.0028 0.002 0.0019
Onchocerca volvulus 0.0014 0.0003 0.0003
Plasmodium falciparum DNase I-like protein, putative 0.0018 0.0007 0.0006
Plasmodium vivax thymidylate kinase, putative 0.104 0.1256 0.1673
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0012
Echinococcus granulosus thyroid hormone receptor alpha 0.0013 0.0002 0.0001
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0006 0.0008
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0018 0.0007 0.0018
Schistosoma mansoni hypothetical protein 0.0142 0.0159 0.0159
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0019 0.0009 0.0007
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0015 0.0004 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0087 0.0092 0.0123
Brugia malayi CCR4 0.0018 0.0007 0.0009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0003 0.0006
Echinococcus multilocularis Metazoa galactosyltransferase 0.0035 0.0029 0.0029
Leishmania major hypothetical protein, conserved 0.0018 0.0007 0.001
Mycobacterium leprae Probable anthranilate phosphoribosyltransferase TrpD 0.0539 0.0644 0.0716
Schistosoma mansoni nuclear receptor nhr-48 0.0013 0.0002 0.0001
Loa Loa (eye worm) galactosyltransferase 0.0035 0.0029 0.004
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0028 0.002 0.0019
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.006 0.006 0.0079
Entamoeba histolytica DNA polymerase delta catalytic subunit, putative 0.0163 0.0185 0.0471
Brugia malayi nuclear hormone receptor 0.0013 0.0002 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0002 0.0001
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0122 0.0309
Echinococcus multilocularis beta LACTamase domain containing family member 0.0033 0.0026 0.0026
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0051 0.0048 0.0047
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0058 0.0056 0.0061
Leishmania major cathepsin L-like protease 0.0014 0.0003 0.0003
Leishmania major DNA polymerase zeta catalytic subunit, putative 0.0031 0.0023 0.0031
Brugia malayi Nuclear hormone receptor-like 1 0.0015 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0168 0.0191 0.0265
Onchocerca volvulus 0.0013 0.0002 0.0002
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0026 0.0067
Schistosoma mansoni dihydrofolate reductase 0.041 0.0486 0.0486
Echinococcus granulosus RUN 0.0018 0.0008 0.0007
Brugia malayi thymidylate kinase 0.104 0.1256 0.1743
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0006 0.0008
Onchocerca volvulus 0.0081 0.0085 0.0117
Trichomonas vaginalis DNA polymerase eta, putative 0.0036 0.003 0.0077
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0122 0.0162
Echinococcus multilocularis carboxylesterase 5A 0.0114 0.0125 0.0124
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0045 0.0061
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0018 0.0007 0.0018
Trichomonas vaginalis penicillin-binding protein, putative 0.0033 0.0026 0.0067
Echinococcus multilocularis BC026374 protein (S09 family) 0.0019 0.0009 0.0009
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0022 0.0057
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0081 0.0085 0.0117
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0025 0.0016 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0002 0.0001
Mycobacterium tuberculosis Probable esterase LipL 0.0033 0.0026 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.0028 0.002 0.0027
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.006 0.006 0.0079
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1675 0.2032 0.2032
Schistosoma mansoni zinc finger protein 0.0013 0.0002 0.0001
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0006 0.0005

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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