Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Brugia malayi | proteasome subunit beta type 2 | 0.0063 | 0.1954 | 0.2205 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0099 | 0.3981 | 0.3981 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0099 | 0.3981 | 0.4492 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.1926 | 0.1926 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0099 | 0.3981 | 0.4492 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0185 | 0.8863 | 1 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0185 | 0.8863 | 1 |
Onchocerca volvulus | Notchless protein homolog | 0.0029 | 0 | 0.5 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0099 | 0.3981 | 0.3981 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0185 | 0.8863 | 0.8863 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0063 | 0.1954 | 0.2205 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0063 | 0.1954 | 0.2205 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0185 | 0.8863 | 1 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0063 | 0.1954 | 0.1954 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0099 | 0.3981 | 0.3981 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0063 | 0.1954 | 0.1954 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0185 | 0.8863 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0029 | 0 | 0.5 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0063 | 0.1954 | 0.2205 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0185 | 0.8863 | 1 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0063 | 0.1954 | 0.2205 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Brugia malayi | Proteasome A-type and B-type family protein | 0.0185 | 0.8863 | 1 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0099 | 0.3981 | 0.4492 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Mycobacterium ulcerans | proteasome PrcB | 0.0185 | 0.8863 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0099 | 0.3981 | 0.4492 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0185 | 0.8863 | 0.8863 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0185 | 0.8863 | 1 |
Echinococcus multilocularis | geminin | 0.0205 | 1 | 1 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0099 | 0.3981 | 0.4492 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0185 | 0.8863 | 1 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0063 | 0.1954 | 0.2205 |
Brugia malayi | proteasome subunit beta type 1 | 0.0099 | 0.3981 | 0.4492 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0063 | 0.1954 | 0.2205 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0063 | 0.1954 | 0.1954 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0099 | 0.3981 | 0.4492 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0185 | 0.8863 | 1 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0063 | 0.1954 | 0.2205 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0063 | 0.1954 | 0.1954 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0185 | 0.8863 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0185 | 0.8863 | 0.8863 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0099 | 0.3981 | 0.4492 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.