Detailed information for compound 254880

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 304.404 | Formula: C17H20O3S
  • H donors: 1 H acceptors: 3 LogP: 3.81 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(c1ccc2c(c1)C(=O)[C@H]1CCCC[C@@H]1CS2)C
  • InChi: 1S/C17H20O3S/c1-10(17(19)20)11-6-7-15-14(8-11)16(18)13-5-3-2-4-12(13)9-21-15/h6-8,10,12-13H,2-5,9H2,1H3,(H,19,20)/t10?,12-,13+/m1/s1
  • InChiKey: FXLVXJUAOPGPAG-SOYIIFOFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.024 0.0355 0.0513
Schistosoma mansoni tar DNA-binding protein 0.0248 0.037 0.0497
Echinococcus multilocularis thyroid hormone receptor alpha 0.0153 0.0203 0.0203
Echinococcus multilocularis dna polymerase kappa 0.0084 0.008 0.008
Toxoplasma gondii exonuclease III APE 0.0056 0.0031 0.0259
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Echinococcus multilocularis histone acetyltransferase MYST2 0.0109 0.0124 0.0124
Echinococcus granulosus histone lysine methyltransferase setb 0.0169 0.0231 0.0318
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0063 0.0689
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Schistosoma mansoni thyroid hormone receptor 0.0153 0.0203 0.0267
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0134 0.0554
Schistosoma mansoni endoplasmin 0.0109 0.0126 0.016
Echinococcus granulosus intermediate filament protein 0.0079 0.0072 0.0099
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.008 0.0074 0.0074
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0072 0.006 0.0262
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0146 0.0612
Trypanosoma brucei DNA polymerase eta, putative 0.0055 0.003 0.0045
Schistosoma mansoni hypothetical protein 0.0286 0.0436 0.0587
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0064 0.0045 0.0049
Loa Loa (eye worm) hypothetical protein 0.0079 0.0072 0.0348
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0031 0.0038
Brugia malayi intermediate filament protein 0.0079 0.0072 0.0568
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0448
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0153 0.0203 0.0279
Trypanosoma brucei lanosterol synthase 0.0065 0.0048 0.0071
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.006 0.0038 0.0274
Schistosoma mansoni intermediate filament proteins 0.0079 0.0072 0.0086
Trypanosoma cruzi ISWI complex protein 0.0091 0.0094 0.0131
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.1207 0.2057 1
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Giardia lamblia Prenyltransferase 0.006 0.0038 0.0608
Schistosoma mansoni hypothetical protein 0.1207 0.2057 0.282
Entamoeba histolytica deoxycytidyl transferase, putative 0.0055 0.003 0.0184
Schistosoma mansoni nuclear receptor 0.0072 0.006 0.0071
Loa Loa (eye worm) hypothetical protein 0.0095 0.0101 0.0492
Echinococcus multilocularis Niemann Pick C1 protein 0.0987 0.1669 0.1669
Echinococcus granulosus endoplasmin 0.0094 0.0098 0.0135
Onchocerca volvulus 0.0074 0.0063 0.0276
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0153 0.0203 0.1719
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0054 0.0572
Loa Loa (eye worm) hypothetical protein 0.0121 0.0147 0.0713
Treponema pallidum fructose-bisphosphate aldolase 0.0313 0.0484 1
Brugia malayi hypothetical protein 0.0081 0.0076 0.0604
Echinococcus granulosus tar DNA binding protein 0.0248 0.037 0.0509
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0146 0.0565
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) mbt repeat family protein 0.0095 0.0101 0.0492
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.008 0.0111
Echinococcus multilocularis L aminoadipate semialdehyde 0.0089 0.009 0.009
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.024 0.0355 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0058 0.0622
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0102 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0095 0.0101 0.0489
Trypanosoma brucei heat shock protein 90, putative 0.0109 0.0126 0.0186
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Brugia malayi nuclear receptor RXR 0.0072 0.006 0.047
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0467 0.0755 0.0755
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0031 0.0282
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0063 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0013 0.0053
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0081 0.0076 0.0368
Loa Loa (eye worm) doublecortin family protein 0.0058 0.0035 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0153 0.0203 0.0267
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0146 0.6857
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0031 0.0887
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0031 0.0046
Schistosoma mansoni lamin 0.0079 0.0072 0.0086
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0031 0.0216
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0095 0.0095
Onchocerca volvulus 0.0103 0.0114 0.0522
Trichomonas vaginalis helicase, putative 0.0066 0.005 0.0517
Trypanosoma brucei DNA polymerase IV, putative 0.0084 0.008 0.0119
Schistosoma mansoni tar DNA-binding protein 0.0248 0.037 0.0497
Brugia malayi jmjC domain containing protein 0.0315 0.0487 0.4209
Echinococcus granulosus microtubule associated protein 2 0.1577 0.2709 0.3725
Schistosoma mansoni jumonji/arid domain-containing protein 0.0222 0.0324 0.0434
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0078 0.0071 0.5899
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Trypanosoma brucei unspecified product 0.0077 0.0068 0.01
Brugia malayi beta-lactamase 0.0074 0.0063 0.0495
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0146 0.0565
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0448
Schistosoma mansoni tar DNA-binding protein 0.0248 0.037 0.0497
Trypanosoma cruzi heat shock protein 85, putative 0.0109 0.0126 0.0178
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0054 0.1706
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0036 0.0306
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0146 0.1219
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0075 0.0065 0.009
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.1207 0.2057 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0701 0.1167 0.1594
Loa Loa (eye worm) hypothetical protein 0.0296 0.0455 0.2209
Brugia malayi nuclear hormone receptor 0.0072 0.006 0.047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Brugia malayi hypothetical protein 0.0058 0.0035 0.0249
Echinococcus multilocularis protein dispatched 1 0.0338 0.0528 0.0528
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.006 0.0038 0.0185
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0052 0.0024 0.0028
Trichomonas vaginalis importin beta-1, putative 0.0048 0.0017 0.0099
Plasmodium falciparum zinc finger protein, putative 0.0046 0.0014 0.026
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0064 0.0045 0.0045
Echinococcus granulosus chromobox protein 1 0.0216 0.0314 0.0432
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0031 0.0887
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0009 0.0009
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0153 0.0203 0.0279
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0035 0.0048
Loa Loa (eye worm) pigment dispersing factor receptor c 0.03 0.0461 0.224
Echinococcus granulosus dna polymerase kappa 0.0084 0.008 0.011
Brugia malayi Bromodomain containing protein 0.0084 0.008 0.0644
Loa Loa (eye worm) DR-78 0.0072 0.006 0.0294
Toxoplasma gondii heat shock protein HSP90 0.0109 0.0126 0.1249
Trypanosoma brucei hypothetical protein, conserved 0.022 0.032 0.0474
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0153 0.0203 0.1719
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.01 0.01
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0075 0.0065 0.0065
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0063 0.0086
Brugia malayi Probable ClpP-like protease 0.0078 0.0071 0.0559
Brugia malayi follicle stimulating hormone receptor 0.023 0.0337 0.2896
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0009 0.0088
Schistosoma mansoni myst-related protein 0.0046 0.0014 0.0007
Mycobacterium tuberculosis Conserved hypothetical protein 0.0055 0.003 0.0044
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.0448 0.0663
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0385 0.061 0.061
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0192 0.0265
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0083 0.0305
Treponema pallidum heat shock protein 90 0.0094 0.0098 0.1468
Brugia malayi ecdysteroid receptor 0.0153 0.0203 0.1719
Onchocerca volvulus 0.0158 0.0211 0.0995
Schistosoma mansoni importin beta-1 0.0059 0.0037 0.0038
Brugia malayi jmjC domain containing protein 0.0052 0.0024 0.0153
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0071 0.0671
Onchocerca volvulus Bile acid receptor homolog 0.0153 0.0203 0.0957
Loa Loa (eye worm) beta-lactamase 0.0074 0.0063 0.0308
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0063 0.0207
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0063 0.0207
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0054 0.0072
Trypanosoma brucei squalene monooxygenase, putative 0.052 0.0849 0.1258
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Loa Loa (eye worm) hypothetical protein 0.0046 0.0013 0.0065
Trypanosoma cruzi protein farnesyltransferase, putative 0.006 0.0038 0.0048
Brugia malayi hypothetical protein 0.0158 0.0211 0.1789
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0063 0.0158
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0169 0.0231 0.0305
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0083 0.0305
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.013 0.013
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Echinococcus granulosus dna polymerase eta 0.0055 0.003 0.0042
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0146 0.0203
Toxoplasma gondii thioredoxin reductase 0.005 0.0021 0.0152
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0059 0.0037 0.0178
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0023 0.0597
Plasmodium vivax multidomain scavenger receptor, putative 0.0058 0.0035 0.1023
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0153 0.0203 0.0267
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus multilocularis frizzled 0.0045 0.0013 0.0013
Schistosoma mansoni transcription factor LCR-F1 0.029 0.0444 0.0598
Entamoeba histolytica hypothetical protein 0.029 0.0444 0.3814
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0315 0.0487 0.0487
Echinococcus multilocularis frizzled 4 0.0045 0.0013 0.0013
Echinococcus granulosus protein farnesyltransferase subunit beta 0.006 0.0038 0.0052
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0177 0.0254
Trypanosoma cruzi heat shock protein 85, putative 0.0109 0.0126 0.0178
Mycobacterium ulcerans beta-lactamase 0.0074 0.0063 0.0158
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0021 0.0123
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi phytoene synthase, putative 0.1207 0.2057 0.3043
Brugia malayi glutathione reductase 0.005 0.0021 0.0127
Echinococcus multilocularis zinc finger protein 0.0145 0.0188 0.0188
Onchocerca volvulus 0.0043 0.0009 0.001
Trypanosoma cruzi heat shock protein 85, putative 0.009 0.0091 0.0127
Brugia malayi Nuclear hormone receptor E75 0.0072 0.006 0.047
Brugia malayi MH2 domain containing protein 0.0139 0.0178 0.1496
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0388 0.0615 0.0846
Echinococcus granulosus jumonji domain containing 1A 0.0052 0.0024 0.0033
Brugia malayi Thioredoxin reductase 0.005 0.0021 0.0127
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.0178 0.0863
Loa Loa (eye worm) PHD-finger family protein 0.0123 0.015 0.073
Echinococcus granulosus RUN 0.0058 0.0035 0.0048
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0081 0.0076 0.0092
Brugia malayi ecdysone receptor 0.0072 0.006 0.047
Entamoeba histolytica hypothetical protein 0.0046 0.0014 0.0042
Echinococcus multilocularis JmjC domain containing protein 4 0.0052 0.0024 0.0024
Onchocerca volvulus 0.0293 0.0448 0.2154
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0063 0.0689
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0146 0.1219
Schistosoma mansoni hypothetical protein 0.417 0.7272 1
Brugia malayi Doublecortin family protein 0.0058 0.0035 0.0249
Brugia malayi beta-lactamase family protein 0.0074 0.0063 0.0495
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Trypanosoma cruzi heat shock protein 90, putative 0.0057 0.0033 0.0041
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0147 0.0192 0.2333
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0063 0.2242
Loa Loa (eye worm) intermediate filament protein 0.0079 0.0072 0.0348
Loa Loa (eye worm) heat shock protein 90 0.0109 0.0126 0.061
Mycobacterium leprae Probable lipase LipE 0.0074 0.0063 0.2242
Loa Loa (eye worm) glutathione reductase 0.005 0.0021 0.0103
Onchocerca volvulus 0.0113 0.0132 0.0611
Schistosoma mansoni heat shock protein 0.0056 0.0033 0.0032
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0153 0.0203 0.0267
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0484 0.4167
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.0007 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0031 0.0282
Loa Loa (eye worm) hypothetical protein 0.0058 0.0035 0.0171
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0056 0.0033 0.0125
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0224 0.0327 0.0449
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Toxoplasma gondii aldehyde dehydrogenase 0.024 0.0355 0.366
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.006 0.0038 0.0367
Brugia malayi Endoplasmin precursor 0.0109 0.0126 0.104
Mycobacterium ulcerans hypothetical protein 0.0154 0.0204 0.0852
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0095 0.0755
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0078 0.0071 0.2299
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0063 0.0207
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Onchocerca volvulus 0.005 0.0021 0.0069
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0153 0.0203 0.0987
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0169 0.0231 0.0305
Schistosoma mansoni cpg binding protein 0.0293 0.0448 0.0605
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Loa Loa (eye worm) hypothetical protein 0.0058 0.0035 0.0171
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0036 0.005
Plasmodium falciparum heat shock protein 90, putative 0.0053 0.0026 0.0684
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Echinococcus multilocularis chromobox protein 1 0.0216 0.0314 0.0314
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0024 0.0118
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Schistosoma mansoni chromobox protein 0.0216 0.0314 0.042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.032 0.0467
Loa Loa (eye worm) hypothetical protein 0.0492 0.08 0.3886
Onchocerca volvulus 0.0058 0.0035 0.0138
Schistosoma mansoni hypothetical protein 0.0592 0.0974 0.1329
Trichomonas vaginalis DNA polymerase eta, putative 0.0084 0.008 0.0904
Trypanosoma cruzi squalene synthase, putative 0.3873 0.6748 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0413 0.066 0.0907
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.03 0.0461 0.3979
Echinococcus granulosus nuclear receptor nhr 48 0.0072 0.006 0.0083
Echinococcus granulosus heat shock protein 90 0.0109 0.0126 0.0173
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0153 0.0203 0.0279
Brugia malayi orphan nuclear receptor NR2E1 0.0072 0.006 0.047
Brugia malayi jmjC domain containing protein 0.0222 0.0324 0.2783
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0448 0.0656
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0146 0.0203
Echinococcus multilocularis nuclear receptor nhr 48 0.0072 0.006 0.006
Loa Loa (eye worm) patched family protein 0.0042 0.0007 0.0033
Brugia malayi chromobox protein homolog 3 0.0121 0.0147 0.1225
Echinococcus granulosus Nuclear hormone receptor HR96 0.0072 0.006 0.0083
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0413 0.066 0.0907
Echinococcus multilocularis dnaJ subfamily B 0.417 0.7272 0.7272
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Entamoeba histolytica heat shock protein 90, putative 0.0109 0.0126 0.1021
Plasmodium falciparum importin beta, putative 0.0059 0.0037 0.1072
Onchocerca volvulus 0.0074 0.0063 0.0276
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0153 0.0202 0.0843
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.0157 0.0665
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.029 0.0444 0.061
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Echinococcus multilocularis peptidase Clp (S14 family) 0.0051 0.0023 0.0023
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0063 0.0207
Echinococcus multilocularis jumonji domain containing 1A 0.0052 0.0024 0.0024
Echinococcus multilocularis expressed conserved protein 0.0649 0.1074 0.1074
Schistosoma mansoni hypothetical protein 0.0091 0.0094 0.0117
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0056 0.0033 0.0204
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0013 0.002
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.024 0.0355 0.1638
Echinococcus multilocularis lysine specific demethylase 6a 0.0052 0.0024 0.0024
Mycobacterium ulcerans aldehyde dehydrogenase 0.024 0.0355 0.1597
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0071 0.2299
Loa Loa (eye worm) hypothetical protein 0.0121 0.0146 0.0709
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Entamoeba histolytica hypothetical protein 0.0069 0.0054 0.0394
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0021 0.0023
Onchocerca volvulus 0.0089 0.009 0.0405
Schistosoma mansoni hypothetical protein 0.0205 0.0294 0.0392
Loa Loa (eye worm) hypothetical protein 0.0089 0.009 0.0437
Brugia malayi Calcitonin receptor-like protein seb-1 0.03 0.0461 0.3979
Schistosoma mansoni protein phosphatase 2C 0.0052 0.0024 0.0021
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0063 0.0207
Leishmania major DNA polymerase kappa, putative 0.0062 0.0043 0.005
Echinococcus granulosus geminin 0.1167 0.1987 0.2732
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0063 0.0689
Loa Loa (eye worm) hypothetical protein 0.0283 0.0431 0.2093
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0031 0.0195
Brugia malayi nuclear receptor RXR 0.0081 0.0076 0.0604
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0056 0.0033 0.0033
Brugia malayi Importin beta-1 subunit 0.0059 0.0037 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0084 0.0956
Giardia lamblia PHD finger protein 15 0.0058 0.0036 0.0561
Giardia lamblia Heat shock protein HSP 90-alpha 0.009 0.0091 0.1725
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0153 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Schistosoma mansoni bromodomain containing protein 0.0053 0.0027 0.0024
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0072 0.006 0.0083
Schistosoma mansoni retinoic acid receptor RXR 0.0153 0.0203 0.0267
Echinococcus granulosus phd:f box containing protein 0.0052 0.0024 0.0033
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0031 0.0467
Trypanosoma brucei squalene synthase, putative 0.3873 0.6748 1
Schistosoma mansoni coup transcription factor 0.0153 0.0203 0.0267
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0064 0.0045 0.0062
Echinococcus multilocularis musashi 0.0079 0.0072 0.0072
Brugia malayi jmjC domain containing protein 0.0052 0.0024 0.0153
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus granulosus frizzled 4 0.0045 0.0013 0.0018
Leishmania major squalene monooxygenase-like protein 0.052 0.0849 0.1246
Mycobacterium tuberculosis Conserved protein 0.0074 0.0063 0.0207
Echinococcus granulosus SAM and MBT domain containing protein 0.0095 0.0101 0.0139
Schistosoma mansoni nuclear receptor 0.0072 0.006 0.0071
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.01 0.0138
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0079 0.0072 0.0348
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Brugia malayi nuclear hormone receptor family member odr-7 0.0072 0.006 0.047
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0024 0.0118
Plasmodium falciparum glutathione reductase 0.005 0.0021 0.0521
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0153 0.0203 0.0987
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0153 0.0203 0.0203
Brugia malayi Intermediate filament tail domain containing protein 0.0079 0.0072 0.0568
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0023 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0146 0.0203
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0095 0.0775
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0089 0.009 0.0727
Brugia malayi hypothetical protein 0.0051 0.0023 0.0145
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0021 0.0521
Echinococcus multilocularis geminin 0.1167 0.1987 0.1987
Echinococcus multilocularis RUN 0.0058 0.0035 0.0035
Loa Loa (eye worm) hypothetical protein 0.0121 0.0146 0.0709
Leishmania major DNA polymerase eta, putative 0.0055 0.003 0.0031
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.006 0.0038 0.0329
Schistosoma mansoni rab6-interacting 0.0058 0.0035 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0147 0.1749
Brugia malayi hypothetical protein 0.029 0.0444 0.3827
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0055 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0013 0.002
Toxoplasma gondii heat shock protein 75, putative 0.0056 0.0033 0.027
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0153 0.0203 0.1719
Loa Loa (eye worm) CHromoDomain protein family member 0.0064 0.0045 0.0219
Brugia malayi heat shock protein 90 0.0109 0.0126 0.104
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0023 0.0597
Loa Loa (eye worm) patched family protein 0.0042 0.0007 0.0033
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0072 0.006 0.006
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.006 0.0038 0.0367
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0084 0.008 0.0904
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Echinococcus multilocularis lamin dm0 0.0079 0.0072 0.0072
Echinococcus multilocularis GPCR, family 2 0.0095 0.01 0.01
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0036 0.0306
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0023 0.0597
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0413 0.066 0.0896
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Echinococcus multilocularis sterol regulatory element binding protein 0.0296 0.0455 0.0455
Echinococcus granulosus cpg binding protein 0.0321 0.0498 0.0685
Trichomonas vaginalis esterase, putative 0.0074 0.0063 0.0689
Echinococcus multilocularis chromobox protein 1 0.0216 0.0314 0.0314
Trypanosoma cruzi heat shock protein 90, putative 0.009 0.0091 0.0127
Plasmodium falciparum protein farnesyltransferase subunit beta 0.006 0.0038 0.1127
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus multilocularis polycomb protein SCMH1 0.0095 0.0101 0.0101
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0109 0.0124 0.103
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Mycobacterium ulcerans hypothetical protein 0.0074 0.0063 0.0158
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0063 0.2038
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0448
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Echinococcus multilocularis heat shock protein 90 0.009 0.0091 0.0091
Echinococcus granulosus Protein patched homolog 1 0.0296 0.0455 0.0625
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0072 0.006 0.006
Brugia malayi Pre-SET motif family protein 0.0431 0.0691 0.5999
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0146 0.12
Loa Loa (eye worm) hypothetical protein 0.0229 0.0337 0.1637
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.006 0.0038 0.0367
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0095 0.0128
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Trypanosoma brucei DNA polymerase IV, putative 0.0077 0.0068 0.01
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0146 0.12
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0051 0.0023 0.001
Plasmodium falciparum histone acetyltransferase GCN5 0.0122 0.0148 0.5091
Loa Loa (eye worm) hypothetical protein 0.0158 0.0211 0.1025
Echinococcus granulosus FTZ F1 alpha 0.0153 0.0203 0.0279
Schistosoma mansoni ap endonuclease 0.0056 0.0031 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.009 0.0092 0.0348
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.01 0.0487
Loa Loa (eye worm) acetyltransferase 0.0467 0.0755 0.3671
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0153 0.0203 0.0279
Loa Loa (eye worm) jmjC domain-containing protein 0.0222 0.0324 0.1577
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0313 0.0484 0.4167
Schistosoma mansoni jumonji domain containing protein 0.0052 0.0024 0.0021
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0067 0.0052 0.0052
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0153 0.0203 0.0987
Schistosoma mansoni zinc finger protein 0.0072 0.006 0.0071
Schistosoma mansoni hypothetical protein 0.0095 0.01 0.0125
Giardia lamblia Fructose-bisphosphate aldolase 0.0313 0.0484 1
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.0177 0.0262
Echinococcus granulosus frizzled 0.0045 0.0013 0.0018
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0072 0.006 0.0294
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0078 0.0071 0.0071
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0112 0.013 0.1079
Loa Loa (eye worm) hypothetical protein 0.0255 0.0381 0.1853
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0078 0.0071 0.2647
Plasmodium falciparum acyl-CoA synthetase 0.009 0.0092 0.3075
Echinococcus granulosus tumor protein p63 0.0772 0.1292 0.1777
Schistosoma mansoni hypothetical protein 0.0286 0.0436 0.0587
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.0157 0.7454
Brugia malayi Bromodomain containing protein 0.0476 0.0771 0.6695
Echinococcus multilocularis cpg binding protein 0.0321 0.0498 0.0498
Schistosoma mansoni rab6-interacting 0.0058 0.0035 0.0036
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0045 0.0013 0.0054
Brugia malayi CHE-14 protein 0.0296 0.0455 0.3923
Schistosoma mansoni survival motor neuron protein 0.005 0.0021 0.0016
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0021 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0013 0.0018
Brugia malayi Latrophilin receptor protein 2 0.0095 0.01 0.0818
Mycobacterium tuberculosis Probable reductase 0.0114 0.0134 0.0554
Loa Loa (eye worm) hypothetical protein 0.0047 0.0016 0.0079
Trypanosoma cruzi ISWI complex protein 0.0091 0.0094 0.0131
Brugia malayi TAR-binding protein 0.0248 0.037 0.3181
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0113 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0146 0.0565
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0054 0.0572
Brugia malayi latrophilin 2 splice variant baaae 0.0205 0.0294 0.2516
Schistosoma mansoni hypothetical protein 0.0058 0.0035 0.0036
Echinococcus multilocularis protein patched 0.0296 0.0455 0.0455
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0072 0.006 0.006
Plasmodium falciparum heat shock protein 90, putative 0.0199 0.0284 1
Onchocerca volvulus Huntingtin homolog 0.0492 0.08 0.3866
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0153 0.0203 0.0203
Schistosoma mansoni terminal deoxycytidyl transferase 0.0055 0.003 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0063 0.0495
Schistosoma mansoni frizzled-like receptor 0.0045 0.0013 0.0005
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0063 0.0207
Schistosoma mansoni DNA polymerase eta 0.0055 0.003 0.0029
Schistosoma mansoni zinc finger protein 0.0145 0.0188 0.0246
Leishmania major heat shock protein, putative 0.0056 0.0033 0.0034
Brugia malayi Hsp90 protein 0.0056 0.0033 0.0225
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.008 0.0111
Loa Loa (eye worm) hypothetical protein 0.0423 0.0677 0.3291
Entamoeba histolytica hypothetical protein 0.0048 0.0017 0.0068
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.013 0.0486
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0056 0.0033 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0153 0.0203 0.0987
Plasmodium vivax glutathione reductase, putative 0.005 0.0021 0.0521
Echinococcus multilocularis dna polymerase eta 0.0055 0.003 0.003
Onchocerca volvulus Protein ultraspiracle homolog 0.0153 0.0203 0.0957
Schistosoma mansoni patched 1 0.0296 0.0455 0.0613
Trypanosoma brucei heat shock protein 84, putative 0.0056 0.0033 0.0048
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0153 0.0202 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0627 0.1037 0.5042
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0055 0.003 0.0042
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Brugia malayi PHD-finger family protein 0.0177 0.0244 0.2079
Echinococcus granulosus snurportin 1 0.0627 0.1037 0.1426
Brugia malayi mbt repeat family protein 0.0095 0.0101 0.0827
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Plasmodium vivax JmjC domain containing protein 0.0052 0.0024 0.063
Mycobacterium ulcerans DNA polymerase IV 0.0084 0.008 0.0241
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0153 0.0203 0.0957
Loa Loa (eye worm) jmjC domain-containing protein 0.0052 0.0024 0.0118
Entamoeba histolytica acetyltransferase, GNAT family 0.0122 0.0148 0.1219
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0153 0.0203 0.0267
Schistosoma mansoni jumonji/arid domain-containing protein 0.0222 0.0324 0.0434
Brugia malayi Pre-SET motif family protein 0.0067 0.0052 0.0392
Echinococcus granulosus Niemann Pick C1 protein 0.0987 0.1669 0.2296
Echinococcus multilocularis phd:f box containing protein 0.0052 0.0024 0.0024
Brugia malayi Steroid receptor seven-up type 2 0.0153 0.0203 0.1719
Brugia malayi conserved hypotetical protein 0.0072 0.006 0.047
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0095 0.0101 0.0127
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0072 0.006 0.006
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0103 0.0114 0.0144
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) patched family protein 0.0042 0.0007 0.0033
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.0101 0.0127
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0094 0.0099 0.0123
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0146 0.6857
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.006 0.0038 0.0367
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0062 0.0043 0.0105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0153 0.0203 0.1719
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi heat shock protein 85, putative 0.0109 0.0126 0.0178
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0063 0.0086
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0153 0.0203 0.0267
Brugia malayi nuclear receptor NHR-88 0.0072 0.006 0.047
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.0448 0.0656
Schistosoma mansoni hypothetical protein 0.029 0.0444 0.0598
Trichomonas vaginalis chromobox protein, putative 0.0131 0.0163 0.1956
Echinococcus granulosus jumonji domain containing protein 0.0081 0.0076 0.0105
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0473 0.0765 0.3653
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0153 0.0203 0.0987
Giardia lamblia Histone acetyltransferase GCN5 0.0122 0.0148 0.2925
Brugia malayi hypothetical protein 0.0492 0.08 0.6946
Loa Loa (eye worm) hypothetical protein 0.0492 0.08 0.3886
Echinococcus granulosus sterol regulatory element binding protein 0.0296 0.0455 0.0625
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0072 0.006 0.006
Schistosoma mansoni jumonji domain containing protein 0.0276 0.0418 0.0563
Echinococcus multilocularis peregrin 0.0084 0.008 0.008
Plasmodium falciparum endoplasmin, putative 0.0072 0.006 0.1925
Toxoplasma gondii ABC1 family protein 0.0074 0.0063 0.0594
Schistosoma mansoni hypothetical protein 0.0095 0.01 0.0125
Schistosoma mansoni transcription factor btf3 0.0069 0.0054 0.0062
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0009 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0102 0.0112 0.1311
Trichomonas vaginalis heat shock protein, putative 0.0072 0.006 0.0649
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0054 0.1706
Echinococcus multilocularis frizzled 5 0.0045 0.0013 0.0013
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0102 0.0112 0.1311
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0215 0.0311 0.0311
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0052 0.0024 0.0184
Echinococcus multilocularis lysine specific demethylase 5A 0.0194 0.0275 0.0275
Toxoplasma gondii histone lysine methyltransferase SET1 0.0582 0.0958 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0037 0.0054
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0146 0.1219
Schistosoma mansoni frizzled 0.0045 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0095 0.01 0.0487
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0153 0.0203 0.1719
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0147 0.0192 0.6693
Leishmania major basic transcription factor 3a, putative 0.0069 0.0054 0.0067
Schistosoma mansoni microtubule-associated protein tau 0.1577 0.2709 0.3717
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0078 0.0071 0.0671
Echinococcus multilocularis SAM and MBT domain containing protein 0.0095 0.0101 0.0101
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0017 0.0099
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0052 0.0024 0.0021
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0054 0.0394
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.009 0.0092 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Schistosoma mansoni cellular tumor antigen P53 0.0113 0.0132 0.0169
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.006 0.0038 0.0253
Brugia malayi polk-prov protein 0.0046 0.0013 0.0057
Echinococcus granulosus Squalene phytoene synthase 0.1207 0.2057 0.2829
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.0448 0.065
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0151 0.02 0.02
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0146 0.0565
Mycobacterium tuberculosis Conserved protein 0.0074 0.0063 0.0207
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.003 0.0205
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Brugia malayi jmjC domain containing protein 0.0052 0.0024 0.0153
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0013 0.0018
Echinococcus granulosus peregrin 0.0084 0.008 0.0111
Trichomonas vaginalis chromobox protein, putative 0.0216 0.0314 0.3881
Schistosoma mansoni tar DNA-binding protein 0.0248 0.037 0.0497
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0006 0.0008
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0134 0.0554
Brugia malayi Bromodomain containing protein 0.024 0.0356 0.3055
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.0076 0.0076
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0067 0.0052 0.0058
Echinococcus granulosus mixed lineage leukemia protein mll 0.0075 0.0065 0.009
Onchocerca volvulus Alhambra homolog 0.0058 0.0036 0.0142
Loa Loa (eye worm) histone methyltransferase 0.0093 0.0097 0.0469
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0009 0.0045
Echinococcus granulosus JmjC domain containing protein 4 0.0052 0.0024 0.0033
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.0043 0.0063
Schistosoma mansoni polycystin 1-related 0.0058 0.0035 0.0036
Trypanosoma brucei ISWI complex protein 0.0091 0.0094 0.0139
Brugia malayi beta-lactamase family protein 0.0074 0.0063 0.0495
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0146 0.0565
Loa Loa (eye worm) jmjC domain-containing protein 0.0121 0.0145 0.0707
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Schistosoma mansoni heat shock protein 0.0109 0.0126 0.016
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0104 0.0117 0.0567
Schistosoma mansoni methyl-cpg binding protein mbd 0.0102 0.0113 0.0142
Schistosoma mansoni tar DNA-binding protein 0.0248 0.037 0.0497
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0112 0.013 0.0534
Mycobacterium tuberculosis Conserved protein 0.0074 0.0063 0.0207
Schistosoma mansoni hypothetical protein 0.0286 0.0436 0.0587
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0095 0.0101 0.046
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Plasmodium vivax endoplasmin, putative 0.0109 0.0126 0.428
Onchocerca volvulus 0.0079 0.0072 0.0316
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0009 0.0021
Loa Loa (eye worm) hypothetical protein 0.0081 0.0076 0.0368
Leishmania major hypothetical protein, conserved 0.0074 0.0063 0.008
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0112 0.013 0.0179
Onchocerca volvulus 0.0121 0.0146 0.0678
Toxoplasma gondii hypothetical protein 0.0047 0.0016 0.0098
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0153 0.0203 0.0279
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0031 0.0153
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Brugia malayi ImpB/MucB/SamB family protein 0.0055 0.003 0.0205
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0413 0.066 0.066
Trypanosoma brucei polo-like protein kinase 0.0092 0.0095 0.0141
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0095 0.0118
Trichomonas vaginalis endoplasmin, putative 0.0072 0.006 0.0649
Trypanosoma cruzi lanosterol synthase, putative 0.0065 0.0048 0.0063
Plasmodium vivax heat shock protein 86, putative 0.0109 0.0126 0.428
Echinococcus granulosus zinc finger protein 0.0145 0.0188 0.0259
Loa Loa (eye worm) hypothetical protein 0.0053 0.0027 0.0132
Brugia malayi nuclear hormone receptor family member nhr-6 0.0072 0.006 0.047
Entamoeba histolytica heat shock protein 90, putative 0.0109 0.0126 0.1021
Loa Loa (eye worm) hypothetical protein 0.0094 0.0099 0.0482
Plasmodium falciparum LCCL domain-containing protein 0.0058 0.0035 0.1023
Schistosoma mansoni RAR-like nuclear receptor 0.0153 0.0203 0.0267
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Brugia malayi PHD-finger family protein 0.0058 0.0036 0.0255
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0153 0.0203 0.1719
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.009 0.0091 0.0125
Trypanosoma cruzi squalene synthase, putative 0.3873 0.6748 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0009 0.0006
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0045 0.0013 0.0054
Loa Loa (eye worm) hypothetical protein 0.0081 0.0076 0.0368
Schistosoma mansoni bromodomain containing protein 0.0406 0.0648 0.0879
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.008 0.0111
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0094 0.0098 0.0131
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0062 0.0043 0.005
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0448
Loa Loa (eye worm) hypothetical protein 0.069 0.1148 0.5581
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0072 0.006 0.0071
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0388 0.0615 0.0615
Schistosoma mansoni phosphatidylserine receptor 0.0052 0.0024 0.0021
Toxoplasma gondii HEAT repeat-containing protein 0.0059 0.0037 0.0313
Trypanosoma brucei DNA polymerase IV, putative 0.0084 0.008 0.0119
Loa Loa (eye worm) hypothetical protein 0.0244 0.0363 0.1766
Echinococcus granulosus lysine specific demethylase 5A 0.0222 0.0324 0.0446
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0121 0.0147 0.0682
Schistosoma mansoni hypothetical protein 0.005 0.0021 0.0016
Schistosoma mansoni ap endonuclease 0.0056 0.0031 0.0031
Leishmania major hypothetical protein, conserved 0.0091 0.0094 0.0126
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Trypanosoma cruzi protein farnesyltransferase, putative 0.006 0.0038 0.0048
Echinococcus multilocularis heat shock protein 0.0109 0.0126 0.0126
Onchocerca volvulus 0.0072 0.006 0.0262
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0063 0.0074
Brugia malayi RNA, U transporter 1 0.0167 0.0227 0.1931
Brugia malayi Heterochromatin protein 1 0.0216 0.0314 0.2692
Echinococcus multilocularis frizzled 10 0.0045 0.0013 0.0013
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0413 0.066 0.0896
Onchocerca volvulus Huntingtin homolog 0.0492 0.08 0.3866
Entamoeba histolytica hypothetical protein 0.029 0.0444 0.3814
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Trichomonas vaginalis heat shock protein, putative 0.009 0.0091 0.1042
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0055 0.003 0.0147
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0112 0.013 0.0486
Schistosoma mansoni cpg binding protein 0.0321 0.0498 0.0673
Schistosoma mansoni aldehyde dehydrogenase 0.024 0.0355 0.0476
Trypanosoma cruzi squalene monooxygenase, putative 0.052 0.0849 0.1251
Schistosoma mansoni endoplasmin 0.0109 0.0126 0.016
Echinococcus multilocularis transcription factor btf3 0.0069 0.0054 0.0054
Trypanosoma brucei importin beta-1 subunit, putative 0.0059 0.0037 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0086 0.0084 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0147 0.0192 0.1952
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Echinococcus granulosus polycomb protein SCMH1 0.0095 0.0101 0.0139
Loa Loa (eye worm) heterochromatin protein 1 0.0216 0.0314 0.1527
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0147 0.0192 0.1952
Loa Loa (eye worm) MBCTL1 0.0109 0.0124 0.0605
Echinococcus granulosus lamin 0.0079 0.0072 0.0099
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0063 0.0063
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.0157 0.0665
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0134 0.62
Trichomonas vaginalis set domain proteins, putative 0.049 0.0795 1
Onchocerca volvulus 0.0153 0.0203 0.0957
Loa Loa (eye worm) CXXC zinc finger family protein 0.0293 0.0448 0.218
Loa Loa (eye worm) hypothetical protein 0.0081 0.0076 0.0368
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0153 0.0203 0.1719
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0054 0.0072
Leishmania major hypothetical protein, conserved 0.0052 0.0024 0.0022
Schistosoma mansoni peptidase Clp (S14 family) 0.0078 0.0071 0.0084
Loa Loa (eye worm) hypothetical protein 0.0051 0.0023 0.0114
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0023 0.0027
Echinococcus multilocularis FTZ F1 alpha 0.0153 0.0203 0.0203
Echinococcus granulosus heat shock protein 0.0109 0.0126 0.0173
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Trichomonas vaginalis chromobox protein, putative 0.0131 0.0163 0.1956
Loa Loa (eye worm) hypothetical protein 0.0121 0.0146 0.0709
Echinococcus granulosus Niemann Pick C1 protein 0.069 0.1148 0.1579
Schistosoma mansoni nuclear hormone receptor 0.0072 0.006 0.0071
Loa Loa (eye worm) follicle stimulating hormone receptor 0.023 0.0337 0.164
Trypanosoma cruzi importin beta-1 subunit, putative 0.0048 0.0017 0.0017
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0065 0.0048 0.0133
Trichomonas vaginalis heat shock protein, putative 0.0094 0.0098 0.1128
Trypanosoma cruzi DNA polymerase eta, putative 0.0055 0.003 0.0037
Schistosoma mansoni hypothetical protein 0.0095 0.01 0.0125
Loa Loa (eye worm) hypothetical protein 0.0363 0.0572 0.278
Loa Loa (eye worm) hypothetical protein 0.0109 0.0124 0.0605
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0035 0.0035
Toxoplasma gondii Hsp90 domain-containing protein 0.0199 0.0284 0.2917
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0071 0.0193
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Mycobacterium ulcerans DNA polymerase IV 0.0084 0.008 0.0241
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0109 0.0124 0.0124
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0151 0.02 0.0262
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Echinococcus multilocularis Squalene phytoene synthase 0.1207 0.2057 0.2057
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0169 0.0231 0.0231
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0078 0.0071 0.0866
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0009 0.0006
Schistosoma mansoni kinase 0.0047 0.0016 0.0009
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Brugia malayi hypothetical protein 0.0081 0.0076 0.0604
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0054 0.0498
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0112 0.013 0.0179
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0146 0.0565
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0413 0.066 0.0896
Brugia malayi steroid hormone receptor 0.0153 0.0203 0.1719
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0045 0.0013 0.0063
Schistosoma mansoni hypothetical protein 0.0095 0.01 0.0125
Giardia lamblia Grp94/Hsp90 0.0094 0.0098 0.1866
Echinococcus multilocularis tar DNA binding protein 0.0248 0.037 0.037
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0009 0.0013
Schistosoma mansoni eyes absent homolog 0.0094 0.0099 0.0124
Brugia malayi CXXC zinc finger family protein 0.0293 0.0448 0.3869
Giardia lamblia DINP protein human, muc B family 0.0062 0.0043 0.0703
Echinococcus granulosus heat shock protein 90 0.009 0.0091 0.0125
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0021 0.0029
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0153 0.0203 0.0203
Echinococcus granulosus L aminoadipate semialdehyde 0.0089 0.009 0.0123
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0031 0.005
Echinococcus granulosus chromobox protein 1 0.0216 0.0314 0.0432
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0248 0.037 0.1798
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0054 0.008
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.024 0.0355 0.0355
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.01 0.0138
Trichomonas vaginalis conserved hypothetical protein 0.0296 0.0455 0.5669
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0153 0.0203 0.0987
Echinococcus granulosus peptidase Clp S14 family 0.0051 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0986 0.1668 0.8108
Schistosoma mansoni frizzled-like receptor 0.0045 0.0013 0.0005
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0051 0.0023 0.001
Echinococcus multilocularis microtubule associated protein 2 0.1577 0.2709 0.2709
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0083 0.0305
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0093 0.0097 0.0133
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0153 0.0203 0.1719
Loa Loa (eye worm) hypothetical protein 0.0081 0.0076 0.0368
Trypanosoma cruzi heat shock protein, putative 0.0056 0.0033 0.004
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0153 0.0203 0.0267
Leishmania major hypothetical protein, conserved 0.1207 0.2057 0.3039
Trypanosoma brucei trypanothione reductase 0.005 0.0021 0.0031
Schistosoma mansoni myst-related protein 0.0046 0.0014 0.0007
Echinococcus multilocularis Polycystic kidney disease protein 0.0058 0.0035 0.0035
Echinococcus multilocularis endoplasmin 0.0094 0.0098 0.0098
Brugia malayi jmjC domain containing protein 0.0052 0.0024 0.0153
Echinococcus granulosus histone acetyltransferase KAT2B 0.044 0.0708 0.0974
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0045 0.0013 0.0063
Brugia malayi nuclear hormone receptor 0.0153 0.0203 0.1719
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0067 0.0052 0.047
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0077 0.0069 0.0083
Plasmodium vivax heat shock protein, putative 0.0199 0.0284 1
Plasmodium falciparum phd finger protein, putative 0.0058 0.0036 0.1049
Echinococcus multilocularis importin subunit beta 1 0.0059 0.0037 0.0037
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0153 0.0202 0.0888
Brugia malayi Nuclear hormone receptor-like 1 0.0153 0.0203 0.1719
Trypanosoma cruzi heat shock protein 90, putative 0.0109 0.0126 0.0178
Echinococcus granulosus lysine specific demethylase 6a 0.0052 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.009 0.0092 0.0448
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0153 0.0203 0.0279
Toxoplasma gondii heat shock protein 90, putative 0.0109 0.0126 0.1249
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0153 0.0203 0.1719
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus multilocularis lipoxygenase domain containing protein 0.0058 0.0035 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0153 0.0203 0.1719
Onchocerca volvulus 0.0095 0.0101 0.046
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Trypanosoma cruzi DNA polymerase kappa, putative 0.0084 0.008 0.0111
Trypanosoma brucei protein farnesyltransferase beta subunit 0.006 0.0038 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Onchocerca volvulus 0.0079 0.0072 0.0316
Brugia malayi hypothetical protein 0.0058 0.0035 0.0249
Loa Loa (eye worm) hypothetical protein 0.0058 0.0036 0.0175
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0153 0.0203 0.0203
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0031 0.0038
Schistosoma mansoni loxhd1 0.0058 0.0035 0.0036
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Entamoeba histolytica hypothetical protein 0.029 0.0444 0.3814
Schistosoma mansoni lipoxygenase 0.0224 0.0327 0.0437
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.006 0.0038 0.0367
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0044 0.0011 0.0002
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0072 0.006 0.0083
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0048 0.0017 0.0099
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0094 0.0098 0.4169
Mycobacterium ulcerans aldehyde dehydrogenase 0.024 0.0355 0.1597
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.0076 0.0604
Echinococcus granulosus expressed conserved protein 0.0649 0.1074 0.1478
Loa Loa (eye worm) nuclear receptor NHR-67 0.0072 0.006 0.0294
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0071 0.0058 0.0622
Mycobacterium ulcerans heat shock protein 90 0.0094 0.0098 0.0328
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0385 0.061 0.0839
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0146 0.0612
Loa Loa (eye worm) hypothetical protein 0.0081 0.0076 0.0368
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0296 0.0455 0.2209
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0153 0.0203 0.1719
Mycobacterium ulcerans lipase LipD 0.0074 0.0063 0.0158
Brugia malayi CHD4 protein 0.0064 0.0045 0.0334
Echinococcus multilocularis frizzled 0.0045 0.0013 0.0013
Echinococcus multilocularis lamin 0.0079 0.0072 0.0072
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0081 0.0076 0.0092
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0153 0.0203 0.1719
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0009 0.0014
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.0157 0.0665
Schistosoma mansoni hypothetical protein 0.1167 0.1987 0.2723
Schistosoma mansoni heat shock protein 0.0109 0.0126 0.016
Schistosoma mansoni hypothetical protein 0.0123 0.015 0.0194
Echinococcus granulosus lipoxygenase domain containing protein 0.0058 0.0035 0.0048
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Onchocerca volvulus 0.0074 0.0063 0.0276
Echinococcus granulosus smoothened 0.1007 0.1705 0.2344
Schistosoma mansoni lipoxygenase 0.0119 0.0143 0.0184
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0224 0.0327 0.0327
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0095 0.0463
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0094 0.0099 0.0482
Mycobacterium ulcerans phytoene synthase, CrtB 0.1207 0.2057 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0151 0.02 0.0275
Plasmodium vivax heat shock protein 90, putative 0.0056 0.0033 0.0925
Loa Loa (eye worm) endoplasmin 0.0109 0.0126 0.061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Loa Loa (eye worm) hypothetical protein 0.0077 0.0069 0.0336
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0036 0.0037
Loa Loa (eye worm) hypothetical protein 0.0052 0.0024 0.0118
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0095 0.0431
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0052 0.0024 0.0028
Leishmania major lanosterol synthase, putative 0.0049 0.002 0.0016
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0094 0.0098 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0131 0.0163 0.0761
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Schistosoma mansoni lamin 0.0079 0.0072 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0153 0.0203 0.0987
Echinococcus granulosus frizzled 0.0045 0.0013 0.0018
Trichomonas vaginalis heat shock protein, putative 0.0109 0.0126 0.1481
Schistosoma mansoni aldehyde dehydrogenase 0.024 0.0355 0.0476
Echinococcus granulosus dnaJ subfamily B 0.417 0.7272 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0413 0.066 0.3208
Trypanosoma brucei heat shock protein 90, putative 0.0109 0.0126 0.0186
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0052 0.0024 0.0036
Echinococcus granulosus importin subunit beta 1 0.0059 0.0037 0.005
Plasmodium vivax conserved Plasmodium protein, unknown function 0.0043 0.001 0.0101
Schistosoma mansoni chromobox protein 0.0216 0.0314 0.042
Plasmodium falciparum JmjC domain-containing protein, putative 0.0052 0.0024 0.063
Trypanosoma cruzi lanosterol synthase, putative 0.0065 0.0048 0.0063
Leishmania major squalene synthase, putative 0.3873 0.6748 1
Schistosoma mansoni cpg binding protein 0.0321 0.0498 0.0673
Onchocerca volvulus 0.049 0.0795 0.3842
Mycobacterium ulcerans fatty-acid-CoA ligase 0.009 0.0092 0.03
Loa Loa (eye worm) hypothetical protein 0.0052 0.0024 0.0118
Entamoeba histolytica hypothetical protein 0.029 0.0444 0.3814
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0054 0.0263
Echinococcus multilocularis smoothened 0.1007 0.1705 0.1705
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0134 0.0554
Loa Loa (eye worm) hypothetical protein 0.0055 0.003 0.0147
Leishmania major trypanothione reductase 0.005 0.0021 0.0018
Loa Loa (eye worm) patched family protein 0.0042 0.0007 0.0033
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.01 0.0818
Trichomonas vaginalis heat shock protein, putative 0.0094 0.0098 0.1128
Echinococcus granulosus GPCR family 2 0.0095 0.01 0.0138
Brugia malayi Nuclear hormone receptor-like 1 0.0081 0.0076 0.0604
Leishmania major hypothetical protein, conserved 0.022 0.032 0.0461
Plasmodium falciparum heat shock protein 90 0.0109 0.0126 0.428
Trypanosoma brucei Heat shock protein 83, putative 0.0109 0.0126 0.0186
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0153 0.0203 0.1719
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0063 0.0689
Schistosoma mansoni phd/f-box containing protein 0.0052 0.0024 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0094 0.0098 0.0376
Echinococcus multilocularis Niemann Pick C1 protein 0.069 0.1148 0.1148
Schistosoma mansoni nuclear hormone receptor 0.0072 0.006 0.0071
Schistosoma mansoni steroid hormone receptor ad4bp 0.0153 0.0203 0.0267
Loa Loa (eye worm) RNA binding protein 0.0248 0.037 0.1798
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0431 0.0691 0.3361
Schistosoma mansoni protein farnesyltransferase subunit beta 0.006 0.0038 0.004
Plasmodium vivax farnesyltransferase beta subunit, putative 0.006 0.0038 0.1127
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Onchocerca volvulus 0.0072 0.006 0.0262
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0146 0.12
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0063 0.0074
Echinococcus granulosus transcription factor btf3 0.0069 0.0054 0.0075
Echinococcus granulosus frizzled 0.0045 0.0013 0.0018
Brugia malayi acetyltransferase, GNAT family protein 0.0467 0.0755 0.6557
Echinococcus multilocularis snurportin 1 0.0627 0.1037 0.1037
Trypanosoma cruzi hypothetical protein, conserved 0.022 0.032 0.0467
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0013 0.0053
Brugia malayi RNA binding protein 0.0248 0.037 0.3181
Loa Loa (eye worm) hypothetical protein 0.0074 0.0063 0.0308
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0072 0.006 0.0262
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0036 0.1049
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Leishmania major farnesyltransferase beta subunit 0.006 0.0038 0.0043
Brugia malayi PHD-finger family protein 0.0047 0.0016 0.0082
Echinococcus granulosus thyroid hormone receptor alpha 0.0072 0.006 0.0083
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0023 0.0035
Loa Loa (eye worm) patched family protein 0.0042 0.0007 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.0147 0.1749
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0031 0.0033
Plasmodium falciparum thioredoxin reductase 0.005 0.0021 0.0521
Leishmania major importin beta-1 subunit, putative 0.0048 0.0017 0.0011
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0026 0.0211
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.0178 0.0863
Echinococcus granulosus ecdysone induced protein 78C 0.0153 0.0203 0.0279
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0095 0.0133
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.006 0.0038 0.0038
Onchocerca volvulus 0.0058 0.0035 0.0138
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.0363 0.0363
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.008 0.0074 0.0101
Giardia lamblia Kinase, PLK 0.0092 0.0095 0.1813
Echinococcus granulosus lamin dm0 0.0079 0.0072 0.0099
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0066 0.005 0.0513
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0093 0.0097 0.0097
Trypanosoma cruzi squalene monooxygenase, putative 0.052 0.0849 0.1251
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Trypanosoma cruzi Heat shock protein 83, putative 0.0109 0.0126 0.0178
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.006 0.0038 0.0367
Leishmania major hypothetical protein, conserved 0.0051 0.0023 0.0021
Brugia malayi SET domain containing protein 0.0044 0.0011 0.0034
Brugia malayi hypothetical protein 0.0072 0.006 0.047
Brugia malayi hypothetical protein 0.0094 0.0099 0.0809
Echinococcus multilocularis heat shock protein 90 0.0109 0.0126 0.0126
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0063 0.0689
Schistosoma mansoni hypothetical protein 0.0627 0.1037 0.1415
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0095 0.0131
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0153 0.0203 0.0279
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0063 0.0207
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0095 0.0133
Loa Loa (eye worm) hypothetical protein 0.0072 0.006 0.0294
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0146 0.0565
Schistosoma mansoni myelin transcription factor 1 myt1 0.0109 0.0124 0.0159
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0036 0.0049
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0467 0.0755 0.1027
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0112 0.013 0.0166
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Trichomonas vaginalis chromobox protein, putative 0.0216 0.0314 0.3881
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Echinococcus multilocularis ecdysone induced protein 78C 0.0153 0.0203 0.0203
Loa Loa (eye worm) hypothetical protein 0.0113 0.0132 0.0642
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0085 0.0083 0.0305
Brugia malayi hypothetical protein 0.0244 0.0363 0.3124
Schistosoma mansoni nuclear receptor nhr-48 0.0072 0.006 0.0071
Brugia malayi mbt repeat family protein 0.0095 0.0101 0.0827
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0013 0.0018
Brugia malayi photoreceptor-specific nuclear receptor 0.0153 0.0203 0.1719
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0009 0.0026
Giardia lamblia Heat shock protein HSP 90-alpha 0.0109 0.0126 0.2451
Brugia malayi RNA recognition motif domain containing protein 0.0248 0.037 0.3181
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.069 0.1148 1
Schistosoma mansoni hypothetical protein 0.0058 0.0036 0.0037
Plasmodium vivax SET domain protein, putative 0.0067 0.0052 0.1613
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0134 0.0554
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0623 0.103 0.1406
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0054 0.0572
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0081 0.0076 0.0104
Brugia malayi nuclear receptor NHR-88 0.0153 0.0203 0.1719
Loa Loa (eye worm) nuclear hormone receptor 0.0072 0.006 0.0294
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0078 0.0071 0.0193
Brugia malayi Niemann-Pick C1 protein precursor 0.069 0.1148 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0153 0.0203 0.0203
Brugia malayi tailless protein 0.0072 0.006 0.047
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0021 0.0023
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0081 0.0076 0.0076
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0315 0.0487 0.067
Schistosoma mansoni thyroid hormone receptor 0.0153 0.0203 0.0267
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.029 0.0444 0.0444
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0063 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0095 0.1095
Trypanosoma brucei heat shock protein, putative 0.0109 0.0126 0.0186
Trichomonas vaginalis bromodomain-containing protein, putative 0.0147 0.0192 0.2333
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0023 0.0027
Brugia malayi nuclear receptor NHR-67 0.0072 0.006 0.047
Loa Loa (eye worm) hypothetical protein 0.0078 0.0071 0.0343
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0036 0.0175
Echinococcus granulosus histone acetyltransferase MYST2 0.0109 0.0124 0.0171
Brugia malayi hypothetical protein 0.0072 0.006 0.047
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Brugia malayi F/Y-rich N-terminus family protein 0.0122 0.0148 0.1238
Loa Loa (eye worm) TAR-binding protein 0.0248 0.037 0.1798
Loa Loa (eye worm) hypothetical protein 0.0133 0.0167 0.0813
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.0007 0.0036
Mycobacterium ulcerans hypothetical protein 0.0121 0.0146 0.0565
Schistosoma mansoni zinc finger protein 0.0091 0.0094 0.0117
Loa Loa (eye worm) steroid hormone receptor 0.0153 0.0203 0.0987
Echinococcus granulosus frizzled 5 0.0045 0.0013 0.0018
Brugia malayi beta-NAC-like protein 0.0069 0.0054 0.0415
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.0363 0.05
Plasmodium vivax acyl-CoA synthetase, putative 0.009 0.0092 0.3075
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0215 0.0311 0.0428
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0078 0.0071 0.0097
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0102 0.0112 0.1311
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0063 0.0158
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0134 0.0554
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0413 0.066 0.5722
Echinococcus multilocularis tumor protein p63 0.0772 0.1292 0.1292
Loa Loa (eye worm) hypothetical protein 0.0153 0.0203 0.0987
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.0204 0.0898
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0036 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0153 0.0203 0.0267
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0072 0.006 0.047
Brugia malayi Nuclear hormone receptor E75 0.0072 0.006 0.047
Loa Loa (eye worm) hypothetical protein 0.0205 0.0294 0.1429
Echinococcus granulosus methyl CpG binding domain protein 2 0.0102 0.0113 0.0155
Loa Loa (eye worm) hypothetical protein 0.1207 0.2057 1
Echinococcus granulosus Nuclear hormone receptor HR96 0.0072 0.006 0.0083
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0313 0.0484 0.6042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.0177 0.0248
Trypanosoma brucei DNA polymerase kappa, putative 0.0084 0.008 0.0119
Schistosoma mansoni hypothetical protein 0.1167 0.1987 0.2723
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0052 0.0024 0.0184
Loa Loa (eye worm) bromodomain containing protein 0.0117 0.0139 0.0673
Echinococcus granulosus Polycystic kidney disease protein 0.0058 0.0035 0.0048
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0072 0.006 0.0071
Loa Loa (eye worm) heat shock protein 75 0.0056 0.0033 0.0158
Schistosoma mansoni sex comb on midleg homolog 0.0095 0.0101 0.0127
Plasmodium vivax importin-beta 2, putative 0.0059 0.0037 0.1072
Loa Loa (eye worm) hypothetical protein 0.0042 0.0007 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0413 0.066 0.066
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.005 0.0517
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0063 0.0094
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0109 0.0124 0.0171
Mycobacterium ulcerans aldehyde dehydrogenase 0.024 0.0355 0.1597
Leishmania major heat shock protein 83-1 0.0109 0.0126 0.0173
Onchocerca volvulus 0.0095 0.0101 0.0457
Loa Loa (eye worm) hypothetical protein 0.03 0.0461 0.224
Loa Loa (eye worm) hypothetical protein 0.0169 0.0231 0.1123
Schistosoma mansoni hypothetical protein 0.0286 0.0436 0.0587
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0021 0.0021
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0075 0.0065 0.0065
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0089 0.009 0.0111

Activities

Activity type Activity value Assay description Source Reference
ED50 (functional) = 40 mg kg-1 Antiinflammatory activity was determined against rats carrageenan hind paw edema, after oral administration; ca. 40 ChEMBL. 2299620

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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