Detailed information for compound 288533

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 351.891 | Formula: C19H28ClN2O2-
  • H donors: 0 H acceptors: 1 LogP: 4.08 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(N([C@@H]1CCCC[C@@H]1N1CCCC1)C)COc1ccccc1.[Cl-]
  • InChi: 1S/C19H28N2O2.ClH/c1-20(19(22)15-23-16-9-3-2-4-10-16)17-11-5-6-12-18(17)21-13-7-8-14-21;/h2-4,9-10,17-18H,5-8,11-15H2,1H3;1H/p-1/t17-,18-;/m1./s1
  • InChiKey: YSBFTVWCIQTGEP-JAXOOIEVSA-M  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0029 0.0355 0.0387
Brugia malayi Inositol-1 0.0036 0.0457 0.0503
Schistosoma mansoni hypothetical protein 0.0009 0.0031 0.0031
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0009 0.0031 0.0031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Echinococcus multilocularis cathepsin L cysteine protease 0.0105 0.1556 0.1556
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Plasmodium falciparum serine repeat antigen 5 0.0033 0.0409 0.1608
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0029 0.0355 0.0387
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0051 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0031 0.0031
Toxoplasma gondii cathepsin B 0.0196 0.3005 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Onchocerca volvulus 0.0105 0.1556 0.7359
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni cathepsin S (C01 family) 0.0033 0.0409 0.0409
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0051 0.0041
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Onchocerca volvulus 0.0105 0.1556 0.7359
Giardia lamblia Cysteine protease 0.0033 0.0409 0.0505
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0105 0.1556 1
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0031 0.0031
Onchocerca volvulus 0.0105 0.1556 0.7359
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.4543 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0409 0.0505
Schistosoma mansoni biogenic amine receptor 0.0009 0.0031 0.0031
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.0409 0.0409
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Giardia lamblia Fructose-bisphosphate aldolase 0.0292 0.4543 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0009 0.0031 0.0031
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0652 0.0652
Mycobacterium ulcerans carboxylesterase, LipT 0.0063 0.0897 0.3583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.1091 0.2071
Echinococcus multilocularis cathepsin L 0.0033 0.0409 0.0409
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0409 0.0409
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) RNA binding protein 0.0063 0.0898 0.1006
Echinococcus granulosus dnaJ subfamily B 0.0396 0.6203 0.6203
Leishmania major cysteine peptidase A (CPA) 0.0105 0.1556 0.4854
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Schistosoma mansoni Smad4 0.0008 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0075 0.1091 0.1225
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0009 0.0031 0.0031
Plasmodium falciparum serine repeat antigen 8 0.0033 0.0409 0.1608
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0027 0.0027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0063 0.0897 0.1624
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0031 0.0031
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0009 0.0031 0.0031
Giardia lamblia Cathepsin L-like protease 0.0033 0.0409 0.0505
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0143 0.2163 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0457 1
Brugia malayi Carboxylesterase family protein 0.0374 0.5848 0.6637
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Schistosoma mansoni tyrosinase precursor 0.0093 0.137 0.137
Giardia lamblia Cathepsin L-like protease 0.0033 0.0409 0.0505
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0031 0.0031
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0559 0.8803 0.8803
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0031 0.0031
Giardia lamblia Cysteine protease 0.0033 0.0409 0.0505
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0051 0.0051
Schistosoma mansoni cpg binding protein 0.0029 0.0358 0.0358
Brugia malayi Cathepsin L-like precursor 0.0075 0.1091 0.1225
Loa Loa (eye worm) hypothetical protein 0.0105 0.1556 0.1754
Giardia lamblia Cathepsin B precursor 0.0033 0.0409 0.0505
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.0409 0.1608
Brugia malayi TAR-binding protein 0.0063 0.0898 0.1006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0051 0.0041
Brugia malayi AKH receptor 0.0009 0.0031 0.0018
Schistosoma mansoni cathepsin B (C01 family) 0.0033 0.0409 0.0409
Schistosoma mansoni cathepsin F (C01 family) 0.0105 0.1556 0.1556
Giardia lamblia Cathepsin B precursor 0.0033 0.0409 0.0505
Plasmodium vivax serine-repeat antigen (SERA) 0.0033 0.0409 0.1608
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0457 0.1355
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0051 0.0041
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1722 0.1943
Treponema pallidum fructose-bisphosphate aldolase 0.0292 0.4543 1
Schistosoma mansoni biogenic amine receptor 0.0009 0.0031 0.0031
Echinococcus granulosus Smad4 0.0008 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0031 0.0031
Brugia malayi Common central domain of tyrosinase family protein 0.0093 0.137 0.1542
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0105 0.1556 0.1754
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0046 0.063 0.07
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Onchocerca volvulus Cathepsin L homolog 0.0105 0.1556 0.7359
Brugia malayi MH2 domain containing protein 0.0115 0.1722 0.1943
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0105 0.1556 0.3139
Loa Loa (eye worm) hypothetical protein 0.0029 0.0355 0.0387
Plasmodium vivax unspecified product 0.0029 0.0355 0.1212
Echinococcus granulosus acetylcholinesterase 0.0374 0.5848 0.5848
Schistosoma mansoni neuropeptide receptor 0.0009 0.0031 0.0031
Echinococcus granulosus smad 0.0008 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0897 0.0897
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.1556 0.3139
Loa Loa (eye worm) hypothetical protein 0.0093 0.137 0.1542
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0898 0.0898
Schistosoma mansoni cpg binding protein 0.0029 0.0358 0.0358
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0457 0.0614
Onchocerca volvulus Cathepsin F homolog 0.0105 0.1556 0.7359
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Echinococcus multilocularis neuropeptide FF receptor 2 0.0009 0.0031 0.0031
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0051 0.0096
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Giardia lamblia Cathepsin B precursor 0.0196 0.3005 0.6467
Echinococcus multilocularis G-protein coupled receptor, putative 0.0009 0.0031 0.0031
Brugia malayi neuropeptide F receptor 0.0009 0.0031 0.0018
Schistosoma mansoni myosin xvIII 0.0009 0.0031 0.0031
Plasmodium falciparum cysteine proteinase falcipain 1 0.0062 0.0874 0.501
Brugia malayi Carboxylesterase family protein 0.0063 0.0897 0.1003
Echinococcus multilocularis smad 0.0008 0.0015 0.0015
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0196 0.3005 0.3005
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0457 0.0614
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Onchocerca volvulus 0.0063 0.0897 0.4177
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1722 0.1943
Entamoeba histolytica cysteine proteinase, putative 0.0062 0.0874 0.1573
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) hypothetical protein 0.0559 0.8803 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0031 0.0031
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0009 0.0031 0.0031
Echinococcus multilocularis acetylcholinesterase 0.0374 0.5848 0.5848
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Loa Loa (eye worm) hypothetical protein 0.0075 0.1091 0.1225
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Plasmodium falciparum serine repeat antigen 9 0.0033 0.0409 0.1608
Loa Loa (eye worm) acetylcholinesterase 1 0.0374 0.5848 0.6637
Brugia malayi hypothetical protein 0.0228 0.3519 0.3987
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0051 0.0051
Echinococcus granulosus neuropeptide receptor 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine proteinase, putative 0.0105 0.1556 0.3139
Brugia malayi neuropeptide F receptor 0.0009 0.0031 0.0018
Plasmodium falciparum cysteine proteinase falcipain 3 0.0105 0.1556 1
Giardia lamblia Encystation-specific protease 0.0033 0.0409 0.0505
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0033 0.0409 0.1608
Echinococcus granulosus cathepsin L cysteine protease 0.0062 0.0874 0.0874
Echinococcus granulosus cathepsin L 0.0062 0.0874 0.0874
Mycobacterium tuberculosis Carboxylesterase LipT 0.0063 0.0897 0.3583
Schistosoma mansoni survival motor neuron protein 0.0046 0.063 0.063
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0897 0.3583
Schistosoma mansoni hypothetical protein 0.0046 0.063 0.063
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0457 0.031
Entamoeba histolytica cysteine protease, putative 0.0105 0.1556 0.3139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0409 0.0409
Brugia malayi Dopamine receptor protein 1 0.0009 0.0031 0.0018
Echinococcus granulosus BC026374 protein S09 family 0.0063 0.0897 0.0897
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0051 0.0051
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0033 0.0409 0.1608
Schistosoma mansoni neuropeptide receptor 0.0009 0.0031 0.0031
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0009 0.0031 0.0031
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0033 0.0409 0.1608
Brugia malayi GnHR receptor homolog 0.0009 0.0031 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0062 0.0874 0.1573
Brugia malayi sulfakinin receptor protein 0.0009 0.0031 0.0018
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0457 0.095
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0009 0.0031 0.0031
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0031 0.0031
Brugia malayi RNA binding protein 0.0063 0.0898 0.1006
Echinococcus multilocularis serotonin receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi putative neuropeptide receptor 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus geminin 0.0156 0.2372 0.2372
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0015 0.0015
Schistosoma mansoni histamine h1 receptor 0.0009 0.0031 0.0031
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0897 0.0897
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0009 0.0031 0.0018
Echinococcus multilocularis somatostatin receptor 0.0009 0.0031 0.0031
Giardia lamblia Cathepsin B precursor 0.0196 0.3005 0.6467
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.083 0.083
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0652 0.0652
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.073 0.1919
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0652 0.0725
Toxoplasma gondii preprocathepsin c precursor, putative 0.0033 0.0409 0.078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Brugia malayi Papain family cysteine protease containing protein 0.0062 0.0874 0.0978
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0009 0.0031 0.0018
Schistosoma mansoni inositol monophosphatase 0.0036 0.0457 0.0457
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0559 0.8803 0.8803
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0031 0.0031
Schistosoma mansoni thyroid hormone receptor 0.001 0.0051 0.0051
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0652 0.0725
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0031 0.0031
Giardia lamblia Cysteine protease 0.0033 0.0409 0.0505
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.3519 0.3519
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0652 0.0652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Echinococcus multilocularis carboxylesterase 5A 0.0374 0.5848 0.5848
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0009 0.0031 0.0031
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0143 0.2163 1
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0051 0.0051
Brugia malayi hypothetical protein 0.0063 0.0897 0.1003
Onchocerca volvulus 0.0046 0.063 0.2891
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) carboxylesterase 0.0374 0.5848 0.6637
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0031 0.0031
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0898 0.1006
Schistosoma mansoni neuroligin 3 (S09 family) 0.0063 0.0897 0.0897
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0189 0.0189
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0031 0.0031
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0031 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi putative neuropeptide receptor NPR1 0.0009 0.0031 0.0018
Echinococcus multilocularis BC026374 protein (S09 family) 0.0063 0.0897 0.0897
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0031 0.0031
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0105 0.1556 0.1556
Echinococcus granulosus allatostatin A receptor 0.0009 0.0031 0.0031
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0031 0.0031
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0409 0.0505
Echinococcus multilocularis G protein coupled receptor 139 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0409 0.0505
Echinococcus multilocularis dnaJ subfamily B 0.0396 0.6203 0.6203
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0051 0.0051
Schistosoma mansoni inositol monophosphatase 0.0036 0.0457 0.0457
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Onchocerca volvulus 0.0033 0.0409 0.1825
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0051 0.0096
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Loa Loa (eye worm) carboxylesterase 0.0063 0.0897 0.1003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0009 0.0031 0.0018
Brugia malayi G-protein coupled receptor 0.0009 0.0031 0.0018
Loa Loa (eye worm) ShTK domain-containing protein 0.0093 0.137 0.1542
Echinococcus granulosus cathepsin L cysteine proteinase 0.0105 0.1556 0.1556
Entamoeba histolytica cysteine proteinase 2 0.0062 0.0874 0.1573
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0062 0.0874 0.1573
Echinococcus granulosus neuropeptide FF receptor 2 0.0009 0.0031 0.0031
Giardia lamblia Cathepsin B precursor 0.0033 0.0409 0.0505
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0031 0.0031
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0409 0.0409
Schistosoma mansoni biogenic amine receptor 0.0009 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0051 0.0041
Schistosoma mansoni neuropeptide receptor 0.0009 0.0031 0.0031
Schistosoma mansoni alpha-1 adrenergic receptor 0.0009 0.0031 0.0031
Schistosoma mansoni amine GPCR 0.0009 0.0031 0.0031
Brugia malayi Tachykinin-like peptides receptor 99D 0.0009 0.0031 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0062 0.0874 0.0874
Echinococcus granulosus g protein coupled receptor 0.0009 0.0031 0.0031
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0409 0.0449
Echinococcus multilocularis Smad4 0.0008 0.0015 0.0015
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0397 0.1054
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0031 0.0031
Plasmodium vivax unspecified product 0.0033 0.0409 0.1608
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0075 0.1091 0.1047
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0051 0.0051
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0015 0.0015
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0189 0.0199
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0409 0.0505
Schistosoma mansoni amine GPCR 0.0009 0.0031 0.0031
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0033 0.0409 0.1608
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0009 0.0031 0.0031
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0062 0.0874 0.0874
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0105 0.1556 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Giardia lamblia Cathepsin B precursor 0.0196 0.3005 0.6467
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0898 0.1006
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.0409 0.1608
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0033 0.0409 0.1608
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.137 0.1542
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0355 0.0192
Echinococcus multilocularis cathepsin L cysteine protease 0.0105 0.1556 0.1556
Entamoeba histolytica cysteine proteinase 1, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.1556 0.1587
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.0409 0.0255
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0051 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0051 0.0051
Loa Loa (eye worm) inositol-1 0.0036 0.0457 0.0503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0051 0.0041
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0457 0.0457
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0409 0.0505
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0033 0.0409 0.0505
Schistosoma mansoni coup transcription factor 0.001 0.0051 0.0051
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0031 0.0031
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0033 0.0409 0.0449
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0051 0.0041
Trypanosoma cruzi cysteine proteinase, putative 0.0062 0.0874 0.0795
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0051 0.0041
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Brugia malayi ShTK domain containing protein 0.0093 0.137 0.1542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Schistosoma mansoni smad1 5 8 and 0.0008 0.0015 0.0015
Brugia malayi cathepsin L precursor 0.0033 0.0409 0.0449
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0652 0.0652
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0063 0.0897 0.0897
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.137 0.1542
Echinococcus granulosus neuropeptide s receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi ecdysteroid receptor 0.001 0.0051 0.0041
Trypanosoma cruzi cysteine proteinase, putative 0.0062 0.0874 0.0795
Echinococcus granulosus cpg binding protein 0.0029 0.0358 0.0358
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0051 0.0041
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.3519 0.3519
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Brugia malayi nuclear receptor NHR-88 0.001 0.0051 0.0041
Echinococcus multilocularis serotonin receptor 0.0009 0.0031 0.0031
Echinococcus granulosus dro:myosuppressin receptor 0.0009 0.0031 0.0031
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0031 0.0018
Brugia malayi RE15519p 0.0009 0.0031 0.0018
Onchocerca volvulus 0.0063 0.0897 0.4177
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0457 0.0457
Echinococcus granulosus somatostatin receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) fibroinase 0.0105 0.1556 0.1754
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0409 0.0449
Loa Loa (eye worm) melatonin receptor type 1A 0.0009 0.0031 0.0018
Schistosoma mansoni microtubule-associated protein tau 0.0635 1 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0009 0.0031 0.0031
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.0409 0.0449
Echinococcus granulosus G protein coupled receptor 139 0.0009 0.0031 0.0031
Echinococcus multilocularis neuroligin 0.0063 0.0897 0.0897
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0196 0.3005 0.6467
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0029 0.0355 0.0387
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0062 0.0874 0.1573
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0031 0.0031
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0051 0.0051
Brugia malayi Melatonin receptor type 1A 0.0009 0.0031 0.0018
Echinococcus multilocularis cysteine protease 0.0105 0.1556 0.1556
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Loa Loa (eye worm) hypothetical protein 0.0374 0.5848 0.6637
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0051 0.0041
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Plasmodium falciparum serine repeat antigen 4 0.0033 0.0409 0.1608
Schistosoma mansoni cathepsin F (C01 family) 0.0105 0.1556 0.1556
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0051 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Giardia lamblia Hypothetical protein 0.0033 0.0409 0.0505
Brugia malayi G protein-coupled receptor F59B2.13 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus 7TM GPCR rhodopsin 0.0009 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0396 0.6203 0.6203
Brugia malayi Dopamine receptor protein 2 0.0009 0.0031 0.0018
Schistosoma mansoni BC026374 protein (S09 family) 0.0063 0.0897 0.0897
Echinococcus granulosus cathepsin l1 0.0105 0.1556 0.1556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0075 0.1091 0.2071
Onchocerca volvulus 0.0139 0.2104 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0051 0.0051
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.1556 0.1587
Schistosoma mansoni opsin-like receptor 0.0009 0.0031 0.0031
Trypanosoma cruzi cruzipain precursor, putative 0.0105 0.1556 0.1587
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0652 0.0652
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0033 0.0409 0.0505
Entamoeba histolytica cysteine proteinase, putative 0.0062 0.0874 0.1573
Plasmodium falciparum serine repeat antigen 3 0.0033 0.0409 0.1608
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0051 0.0041
Trypanosoma brucei cysteine peptidase C (CPC) 0.0196 0.3005 1
Echinococcus multilocularis cathepsin L 0.0062 0.0874 0.0874
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.0409 0.0505
Echinococcus multilocularis g-protein coupled receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) ctsf protein 0.0105 0.1556 0.1754
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0051 0.0051
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0031 0.0031
Schistosoma mansoni cathepsin s 0.0029 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0075 0.1091 0.1225
Schistosoma mansoni hypothetical protein 0.0156 0.2372 0.2372
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0093 0.137 0.1542
Schistosoma mansoni hypothetical protein 0.0156 0.2372 0.2372
Plasmodium vivax vivapain-3 0.0062 0.0874 0.501
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0051 0.0041
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0033 0.0409 0.0505
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0033 0.0409 0.0449
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.1556 0.1587
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0051 0.0051
Brugia malayi Papain family cysteine protease containing protein 0.0062 0.0874 0.0978
Brugia malayi cathepsin L-like precursor 0.0075 0.1091 0.1225
Echinococcus granulosus peptide allatostatin:somatostatin 0.0009 0.0031 0.0031
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0063 0.0897 0.0897
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Echinococcus granulosus FTZ F1 alpha 0.001 0.0051 0.0051
Echinococcus granulosus acetylcholinesterase 0.0374 0.5848 0.5848
Echinococcus granulosus carboxylesterase 5A 0.0374 0.5848 0.5848
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0031 0.0031
Brugia malayi ORL1-like opioid receptor 0.0009 0.0031 0.0018
Brugia malayi cathepsin L-like cysteine proteinase 0.0033 0.0409 0.0449
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Schistosoma mansoni neuropeptide f receptor 76f 0.0009 0.0031 0.0031
Brugia malayi CXXC zinc finger family protein 0.0028 0.0333 0.0362
Trichomonas vaginalis spcc417.12 protein, putative 0.0063 0.0897 0.1624
Plasmodium falciparum serine repeat antigen 7 0.0033 0.0409 0.1608
Plasmodium vivax vivapain-2 0.0105 0.1556 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0051 0.0051
Onchocerca volvulus 0.0093 0.137 0.646
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Onchocerca volvulus 0.001 0.0051 0.0096
Toxoplasma gondii cathepsin CPC1 0.0033 0.0409 0.078
Schistosoma mansoni gliotactin 0.0063 0.0897 0.0897
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis neuropeptide s receptor 0.0009 0.0031 0.0031
Echinococcus granulosus cathepsin l cysteine peptidase 0.0105 0.1556 0.1556
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0051 0.0051
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0051 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0051 0.0041
Schistosoma mansoni tyrosinase precursor 0.0093 0.137 0.137
Schistosoma mansoni smad1 5 8 and 0.0008 0.0015 0.0015
Onchocerca volvulus 0.0105 0.1556 0.7359
Echinococcus granulosus cathepsin b 0.0559 0.8803 0.8803
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0409 0.0409
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni amine GPCR 0.0009 0.0031 0.0031
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Echinococcus granulosus orexin receptor type 2 0.0009 0.0031 0.0031
Echinococcus multilocularis acetylcholinesterase 0.0374 0.5848 0.5848
Brugia malayi nuclear hormone receptor 0.001 0.0051 0.0041
Echinococcus granulosus tachykinin peptides receptor 99D 0.0009 0.0031 0.0031
Schistosoma mansoni ap endonuclease 0.0019 0.0189 0.0189
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0009 0.0031 0.0031
Brugia malayi Serotonin receptor 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0009 0.0031 0.0031
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0196 0.3005 0.3269
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0652 0.0652
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0033 0.0409 0.0409
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0051 0.0051
Brugia malayi hypothetical protein 0.0139 0.2104 0.2377
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0355 0.0387
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0374 0.5848 0.5848
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0033 0.0409 0.0505
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0009 0.0031 0.0018
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0027 0.0014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0409 0.0505
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0009 0.0031 0.0018
Echinococcus granulosus 7tm_1 domain containing protein 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0228 0.3519 0.3987
Brugia malayi G-protein coupled receptor 0.0009 0.0031 0.0018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0874 0.2432
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0051 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0457 0.0614
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0105 0.1556 0.3139
Schistosoma mansoni smad 0.0008 0.0015 0.0015
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Loa Loa (eye worm) hypothetical protein 0.0093 0.137 0.1542
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0009 0.0031 0.0018
Toxoplasma gondii cathepsin CPL 0.0105 0.1556 0.4854
Loa Loa (eye worm) carboxylesterase 0.0063 0.0897 0.1003
Brugia malayi Papain family cysteine protease containing protein 0.0033 0.0409 0.0449
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0033 0.0409 0.0505
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0051 0.0051
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0033 0.0409 0.1608
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0051 0.0096
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Plasmodium vivax vivapain-2 0.0105 0.1556 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0143 0.2163 1
Onchocerca volvulus 0.0063 0.0897 0.4177
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0033 0.0409 0.1608
Echinococcus multilocularis orexin receptor type 2 0.0009 0.0031 0.0031
Echinococcus granulosus g protein coupled receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus multilocularis cpg binding protein 0.0029 0.0358 0.0358
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0062 0.0874 0.0874
Echinococcus granulosus cathepsin l1 0.0075 0.1091 0.1091
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0027 0.0027
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0031 0.0031
Onchocerca volvulus 0.0093 0.137 0.646
Echinococcus granulosus g-protein coupled receptor 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine proteinase, putative 0.0075 0.1091 0.2071
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0457 0.031
Schistosoma mansoni smad1 5 8 and 0.0008 0.0015 0.0015
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0009 0.0031 0.0018
Brugia malayi Cathepsin L-like precursor 0.0075 0.1091 0.1225
Brugia malayi Carboxylesterase family protein 0.0063 0.0897 0.1003
Schistosoma mansoni opsin-like receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0409 0.0505
Echinococcus granulosus neuropeptide receptor A26 0.0009 0.0031 0.0031
Echinococcus multilocularis dro:myosuppressin receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0409 0.0449
Loa Loa (eye worm) cysteine protease 0.0105 0.1556 0.1754
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0033 0.0409 0.0449
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0033 0.0409 0.0409
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0031 0.0031
Echinococcus granulosus cathepsin L 0.0033 0.0409 0.0409
Brugia malayi larval opioid receptor 0.0009 0.0031 0.0018
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0051 0.0041
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0105 0.1556 0.1556
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0051 0.0041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0874 0.2432
Schistosoma mansoni growth hormone secretagogue receptor 0.0009 0.0031 0.0031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0652 0.0652
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0051 0.0041
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Toxoplasma gondii cathepsin CPC2 0.0033 0.0409 0.078
Brugia malayi cathepsin Z-like cysteine proteinase 0.0033 0.0409 0.0449
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0033 0.0409 0.1608
Onchocerca volvulus 0.0063 0.0897 0.4177
Giardia lamblia Cathepsin B precursor 0.0033 0.0409 0.0505
Schistosoma mansoni cpg binding protein 0.0028 0.0333 0.0333
Onchocerca volvulus 0.0028 0.0333 0.1459
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0559 0.8803 0.8803
Onchocerca volvulus 0.0093 0.137 0.646
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0063 0.0897 0.0897
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni adenoreceptor 0.0009 0.0031 0.0031
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0063 0.0897 0.3583
Schistosoma mansoni ap endonuclease 0.0019 0.0189 0.0189
Echinococcus multilocularis cathepsin b 0.0559 0.8803 0.8803
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0898 0.0898
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0409 0.0505
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0033 0.0409 0.1608
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0874 0.0795
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0051 0.0041
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0559 0.8803 0.8803
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0898 0.0898
Entamoeba histolytica cysteine protease, putative 0.0033 0.0409 0.0505
Brugia malayi cathepsin B-like cysteine proteinase 0.0559 0.8803 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0033 0.0409 0.1608
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0292 0.4543 1
Plasmodium falciparum serine repeat antigen 1 0.0033 0.0409 0.1608
Brugia malayi Serotonin receptor 0.0009 0.0031 0.0018
Loa Loa (eye worm) cathepsin B 0.0196 0.3005 0.3403
Echinococcus granulosus serotonin receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0409 0.0505
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0033 0.0409 0.0505
Onchocerca volvulus 0.0105 0.1556 0.7359
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0051 0.0041
Brugia malayi cathepsin F-like cysteine proteinase 0.0029 0.0355 0.0387
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0898 0.0898
Giardia lamblia Hypothetical protein 0.0033 0.0409 0.0505
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0051 0.0041
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Brugia malayi Carboxylesterase family protein 0.0374 0.5848 0.6637
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0015 0.0015
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0333 0.0362
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Echinococcus multilocularis sex peptide receptor 0.0009 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0033 0.0409 0.1608
Echinococcus granulosus tar DNA binding protein 0.0063 0.0898 0.0898
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0063 0.0897 0.1003
Brugia malayi Dopamine receptor 0.0009 0.0031 0.0018
Giardia lamblia Cathepsin L precursor 0.0033 0.0409 0.0505
Giardia lamblia Cathepsin B precursor 0.0033 0.0409 0.0505
Plasmodium falciparum serine repeat antigen 6 0.0033 0.0409 0.1608
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0009 0.0031 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Brugia malayi Cathepsin L-like cysteine proteinase 0.0075 0.1091 0.1225
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0898 0.1006
Plasmodium vivax unspecified product 0.0062 0.0874 0.501
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Schistosoma mansoni cathepsin F (C01 family) 0.0075 0.1091 0.1091
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) tyrosinase 1 0.0093 0.137 0.1542
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Echinococcus granulosus g protein coupled receptor 0.0009 0.0031 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0031 0.0031
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi Cathepsin L-like precursor 0.0105 0.1556 0.1754
Echinococcus multilocularis microtubule associated protein 2 0.0635 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0033 0.0409 0.0505
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0062 0.0874 0.0795
Echinococcus granulosus para nitrobenzyl esterase 0.0063 0.0897 0.0897
Schistosoma mansoni hypothetical protein 0.0009 0.0031 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0051 0.0041
Echinococcus granulosus hypothetical protein 0.0009 0.0031 0.0031
Brugia malayi Cathepsin L-like precursor 0.0029 0.0355 0.0387
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Brugia malayi follicle stimulating hormone receptor 0.0009 0.0031 0.0018
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0033 0.0409 0.0409
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Plasmodium falciparum serine repeat antigen 2 0.0033 0.0409 0.1608
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0457 0.095
Onchocerca volvulus Cathepsin L homolog 0.0105 0.1556 0.7359
Brugia malayi Carboxylesterase family protein 0.0063 0.0897 0.1003
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0009 0.0031 0.0018
Onchocerca volvulus 0.0093 0.137 0.646
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0031 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0898 0.0898
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0033 0.0409 0.1608
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0062 0.0874 0.1573
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0031 0.0018
Schistosoma mansoni nuclear hormone receptor 0.001 0.0051 0.0051
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Echinococcus granulosus alpha 1A adrenergic receptor 0.0009 0.0031 0.0031
Schistosoma mansoni acetylcholinesterase 0.0063 0.0897 0.0897
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0009 0.0031 0.0018
Entamoeba histolytica hypothetical protein 0.0033 0.0409 0.0505
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0559 0.8803 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0033 0.0409 0.0409
Onchocerca volvulus 0.0063 0.0897 0.4177
Loa Loa (eye worm) hypothetical protein 0.0374 0.5848 0.6637
Echinococcus multilocularis allatostatin A receptor 0.0009 0.0031 0.0031
Schistosoma mansoni thyroid hormone receptor 0.001 0.0051 0.0051
Brugia malayi steroid hormone receptor 0.001 0.0051 0.0041
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0196 0.3005 1
Brugia malayi Papain family cysteine protease containing protein 0.0105 0.1556 0.1754
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Schistosoma mansoni amine GPCR 0.0009 0.0031 0.0031
Brugia malayi F/Y-rich N-terminus family protein 0.0008 0.0025 0.0012
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0041
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0009 0.0031 0.0031
Trypanosoma cruzi cruzipain precursor, putative 0.0029 0.0355 0.0192
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Giardia lamblia Cysteine protease 0.0033 0.0409 0.0505
Schistosoma mansoni hypothetical protein 0.0009 0.0031 0.0031
Schistosoma mansoni cathepsin C 0.0033 0.0409 0.0409
Onchocerca volvulus 0.0105 0.1556 0.7359
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0457 0.0614
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Trypanosoma cruzi major cysteine proteinase, putative 0.0033 0.0409 0.0255
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0031 0.0031
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Loa Loa (eye worm) TYRA-2 protein 0.0009 0.0031 0.0018
Brugia malayi G protein-coupled receptor 0.0009 0.0031 0.0018
Echinococcus granulosus neuropeptide receptor 0.0009 0.0031 0.0031
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0457 0.095
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Plasmodium vivax vivapain-1 0.0062 0.0874 0.501
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0031 0.0018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0105 0.1556 0.3139
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0033 0.0409 0.0505
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0105 0.1556 0.3139
Brugia malayi fibroinase precursor 0.0033 0.0409 0.0449
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0009 0.0031 0.0031
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0033 0.0409 0.0505
Onchocerca volvulus 0.0075 0.1091 0.5116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0105 0.1556 0.4854
Echinococcus multilocularis cathepsin b 0.0559 0.8803 0.8803
Brugia malayi Carboxylesterase family protein 0.0063 0.0897 0.1003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0051 0.0041
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0105 0.1556 0.1754
Echinococcus granulosus sex peptide receptor 0.0009 0.0031 0.0031
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0051 0.0051
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0189 0.0199
Schistosoma mansoni hypothetical protein 0.0009 0.0031 0.0031
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0031 0.0018
Brugia malayi cathepsin F-like cysteine proteinase 0.0033 0.0409 0.0449
Schistosoma mansoni amine GPCR 0.0009 0.0031 0.0031
Onchocerca volvulus Cathepsin L homolog 0.0033 0.0409 0.1825
Loa Loa (eye worm) hypothetical protein 0.0139 0.2104 0.2377
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0009 0.0031 0.0031
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0093 0.137 0.1542
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.0009 0.0031 0.0031
Echinococcus granulosus fmrfamide receptor 0.0009 0.0031 0.0031
Echinococcus multilocularis neuropeptide receptor A26 0.0009 0.0031 0.0031
Leishmania major cathepsin L-like protease 0.0105 0.1556 0.4854
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0033 0.0409 0.0505
Echinococcus multilocularis geminin 0.0156 0.2372 0.2372
Loa Loa (eye worm) ShTK domain-containing protein 0.0093 0.137 0.1542
Schistosoma mansoni opsin-like receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0051 0.0041
Brugia malayi hypothetical protein 0.0009 0.0031 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.0105 0.1556 0.1587
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0898 0.0898
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0031 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0292 0.4543 1
Trypanosoma cruzi cysteine protease, putative 0.0062 0.0874 0.0795
Echinococcus granulosus cysteine protease 0.0062 0.0874 0.0874
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0031 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0409 0.0449
Echinococcus granulosus cathepsin b 0.0559 0.8803 0.8803
Onchocerca volvulus 0.0105 0.1556 0.7359
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0031 0.0031
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0031 0.0031
Echinococcus granulosus neuroligin 0.0063 0.0897 0.0897
Echinococcus multilocularis cysteine protease 0.0105 0.1556 0.1556
Entamoeba histolytica cysteine protease, putative 0.0062 0.0874 0.1573
Echinococcus multilocularis para nitrobenzyl esterase 0.0063 0.0897 0.0897

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 360 nM Binding affinity for the Opioid receptor kappa 1 ChEMBL. 2832603
Ki (binding) > 1000 nM Binding affinity for the Opioid receptor mu 1 ChEMBL. 2832603

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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