Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0052 | 0.0009 | 0.059 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0001 | 0.0227 |
Mycobacterium tuberculosis | Possible lipase LipU | 0.0302 | 0.0149 | 1 |
Leishmania major | metacaspase, putative | 0.0052 | 0.0009 | 0.059 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0137 | 0.0057 | 0.0057 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0057 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | esterase/lipase | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0007 | 0.0456 |
Mycobacterium ulcerans | carboxylesterase LipQ | 0.0302 | 0.0149 | 1 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0137 | 0.0057 | 0.0057 |
Brugia malayi | aryl-acylamidase | 0.0302 | 0.0149 | 0.9996 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0073 | 0.0021 | 0.0021 |
Trypanosoma brucei | metacaspase | 0.0052 | 0.0009 | 0.059 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0089 | 0.003 | 0.003 |
Treponema pallidum | N-acetylphosphinothricin-tripetide-deacetylase | 0.0302 | 0.0149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.0064 | 0.0064 |
Mycobacterium tuberculosis | Probable carboxylesterase LipQ | 0.0302 | 0.0149 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0052 | 0.0009 | 0.059 |
Brugia malayi | ShTK domain containing protein | 0.0089 | 0.003 | 0.2004 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0137 | 0.0057 | 0.0057 |
Mycobacterium tuberculosis | Probable esterase LipO | 0.0302 | 0.0149 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0047 | 0.2983 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0001 | 0.0001 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0209 | 0.0097 | 0.6496 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0.0049 | 0.0049 |
Echinococcus multilocularis | caspase 3 | 0.0085 | 0.0028 | 0.0028 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0052 | 0.0009 | 0.0589 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0137 | 0.0057 | 0.0057 |
Mycobacterium ulcerans | lipase LipU | 0.0302 | 0.0149 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0001 | 0.0001 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0137 | 0.0057 | 0.0057 |
Mycobacterium ulcerans | hypothetical protein | 0.0302 | 0.0149 | 1 |
Onchocerca volvulus | 0.0047 | 0.0006 | 0.0192 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0009 | 0.0009 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0021 | 0.0021 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0052 | 0.0009 | 0.0009 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.0047 | 0.2983 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.01 | 0.0036 | 0.2225 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0084 | 0.0027 | 0.1814 |
Trichomonas vaginalis | Esterase, putative | 0.0302 | 0.0149 | 0.9996 |
Mycobacterium ulcerans | lipase LipH | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0084 | 0.0027 | 0.1814 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0001 | 0.0001 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0004 | 0.027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Loa Loa (eye worm) | tyrosinase 1 | 0.0089 | 0.003 | 0.003 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0052 | 0.0009 | 0.059 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0052 | 0.0009 | 0.059 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0014 | 0.0928 |
Brugia malayi | Hypothetical tyrosinase-like protein F21C3.2 in chromosome I | 0.0089 | 0.003 | 0.2004 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.0109 | 0.0109 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0006 | 0.0415 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0007 | 0.0007 |
Schistosoma mansoni | lipoxygenase | 0.0114 | 0.0044 | 0.0044 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0089 | 0.003 | 0.2004 |
Brugia malayi | amidase | 0.0123 | 0.0049 | 0.3277 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0137 | 0.0057 | 0.0057 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0004 | 0.027 |
Brugia malayi | Cell death protein 3 precursor | 0.01 | 0.0036 | 0.2401 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1582 | 0.087 | 0.087 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0043 | 0.0004 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0021 | 0.0021 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0001 | 0.0001 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0004 | 0.0004 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0061 | 0.0014 | 0.0014 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0047 | 0.3141 |
Mycobacterium ulcerans | lipase/esterase LipN | 0.0302 | 0.0149 | 1 |
Mycobacterium ulcerans | esterase LipO | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0084 | 0.0027 | 0.1814 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0302 | 0.0149 | 0.9996 |
Brugia malayi | hypoxia-induced factor 1 | 0.0176 | 0.0079 | 0.5265 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0052 | 0.0009 | 0.059 |
Trichomonas vaginalis | Esterase, putative | 0.0302 | 0.0149 | 0.9996 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0137 | 0.0057 | 0.0057 |
Mycobacterium ulcerans | lipase LipI | 0.0302 | 0.0149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Echinococcus multilocularis | caspase | 0.0137 | 0.0057 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0006 | 0.0006 |
Mycobacterium ulcerans | hypothetical protein | 0.0084 | 0.0027 | 0.1815 |
Onchocerca volvulus | 0.0089 | 0.003 | 0.1819 | |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0047 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.0109 | 0.0109 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0006 | 0.0006 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0061 | 0.0014 | 0.0014 |
Echinococcus multilocularis | caspase 2 | 0.01 | 0.0036 | 0.0036 |
Plasmodium falciparum | esterase, putative | 0.0084 | 0.0027 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0302 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | aryl-acylamidase | 0.0302 | 0.0149 | 0.0149 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0037 | 0.0037 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0198 | 0.0091 | 0.6007 |
Mycobacterium tuberculosis | Probable lipase/esterase LipN | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0006 | 0.0006 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0123 | 0.0049 | 0.0049 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0089 | 0.003 | 0.2004 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0021 | 0.0021 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0114 | 0.0044 | 0.0044 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0137 | 0.0057 | 0.0057 |
Onchocerca volvulus | 0.0089 | 0.003 | 0.1819 | |
Loa Loa (eye worm) | ammd protein | 0.0302 | 0.0149 | 0.0149 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0014 | 0.0014 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9D | 0.0302 | 0.0149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0004 | 0.0004 |
Toxoplasma gondii | alpha/beta hydrolase fold domain-containing protein | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.003 | 0.003 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0052 | 0.0009 | 0.059 |
Trichomonas vaginalis | Esterase, putative | 0.0302 | 0.0149 | 0.9996 |
Schistosoma mansoni | tyrosinase precursor | 0.0089 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Onchocerca volvulus | 0.0048 | 0.0007 | 0.0234 | |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0006 | 0.0006 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0073 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0149 | 0.0064 | 0.0064 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0073 | 0.0021 | 0.0021 |
Schistosoma mansoni | amidase | 0.0123 | 0.0049 | 0.0049 |
Plasmodium falciparum | lysophospholipase, putative | 0.0084 | 0.0027 | 1 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0043 | 0.0004 | 0.0004 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | carboxylesterase | 0.0073 | 0.0021 | 0.0021 |
Brugia malayi | hypothetical protein | 0.0191 | 0.0087 | 0.5821 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0047 | 0.0047 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Schistosoma mansoni | lipoxygenase | 0.008 | 0.0025 | 0.0025 |
Mycobacterium tuberculosis | Probable esterase LipM | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0021 | 0.0021 |
Mycobacterium tuberculosis | Probable esterase/lipase LipF | 0.0302 | 0.0149 | 1 |
Loa Loa (eye worm) | ShTK domain-containing protein | 0.0089 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0037 | 0.0037 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0004 | 0.027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0084 | 0.0027 | 0.1815 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.7812 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0001 | 0.0227 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | valacyclovir hydrolase, putative | 0.0084 | 0.0027 | 0.1814 |
Echinococcus granulosus | carboxylesterase 5A | 0.0073 | 0.0021 | 0.0021 |
Brugia malayi | PAS domain containing protein | 0.0057 | 0.0012 | 0.0783 |
Trypanosoma cruzi | metacaspase, putative | 0.0052 | 0.0009 | 0.059 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Mycobacterium ulcerans | lysophospholipase | 0.0084 | 0.0027 | 0.1815 |
Trypanosoma cruzi | Alpha/beta hydrolase domain-containing protein | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0004 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.0087 | 0.0087 |
Mycobacterium ulcerans | esterase LipW | 0.0302 | 0.0149 | 1 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0043 | 0.0004 | 0.149 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0.0049 | 0.0049 |
Brugia malayi | bHLH-PAS transcription factor | 0.0042 | 0.0003 | 0.0227 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Mycobacterium tuberculosis | Probable acetyl-hydrolase/esterase LipR | 0.0302 | 0.0149 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0047 | 0.0006 | 0.0419 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0123 | 0.0049 | 0.0049 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0198 | 0.0091 | 0.6095 |
Schistosoma mansoni | jumonji domain containing protein | 0.0061 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0176 | 0.0079 | 0.0079 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.0109 | 0.0109 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0084 | 0.0027 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0001 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0089 | 0.003 | 0.003 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Echinococcus granulosus | single minded 2 | 0.0042 | 0.0003 | 0.0003 |
Brugia malayi | jmjC domain containing protein | 0.0061 | 0.0014 | 0.0928 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.7812 | 1 | 1 |
Plasmodium falciparum | lysophospholipase, putative | 0.0084 | 0.0027 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0137 | 0.0057 | 0.0057 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0021 | 0.0021 |
Trypanosoma brucei | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0302 | 0.0149 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0047 | 0.0006 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 1.7812 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0021 | 0.0021 |
Plasmodium falciparum | lysophospholipase, putative | 0.0084 | 0.0027 | 1 |
Mycobacterium tuberculosis | Probable lipase LipH | 0.0302 | 0.0149 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0302 | 0.0149 | 0.0149 |
Mycobacterium ulcerans | lipase LipU | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0006 | 0.0006 |
Trypanosoma cruzi | metacaspase, putative | 0.0052 | 0.0009 | 0.059 |
Leishmania major | monoglyceride lipase, putative | 0.0084 | 0.0027 | 0.1815 |
Trypanosoma cruzi | monoglyceride lipase, putative | 0.0084 | 0.0027 | 0.1815 |
Echinococcus granulosus | caspase | 0.0137 | 0.0057 | 0.0057 |
Onchocerca volvulus | 0.0089 | 0.003 | 0.1819 | |
Brugia malayi | hypothetical protein | 0.0231 | 0.0109 | 0.7324 |
Mycobacterium leprae | Possible lipase LipU | 0.0302 | 0.0149 | 1 |
Mycobacterium ulcerans | acetyl hydrolase MbtJ | 0.0302 | 0.0149 | 1 |
Trypanosoma brucei | metacaspase MCA2 | 0.0052 | 0.0009 | 0.059 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0137 | 0.0057 | 0.0057 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0149 | 0.0064 | 0.4252 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0209 | 0.0097 | 0.6496 |
Brugia malayi | Common central domain of tyrosinase family protein | 0.0089 | 0.003 | 0.2004 |
Echinococcus granulosus | caspase 3 | 0.0085 | 0.0028 | 0.0028 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0027 | 0.1814 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0036 | 0.0036 |
Entamoeba histolytica | hydrolase, alpha/beta fold family domain containing protein | 0.0084 | 0.0027 | 1 |
Echinococcus granulosus | caspase 8 | 0.0052 | 0.0009 | 0.0009 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.01 | 0.0036 | 0.0036 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0043 | 0.0004 | 0.0004 |
Onchocerca volvulus | 0.0302 | 0.0149 | 1 | |
Schistosoma mansoni | single-minded | 0.0057 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0049 | 0.0049 |
Echinococcus multilocularis | hormone sensitive lipase | 1.7812 | 1 | 1 |
Trypanosoma cruzi | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Trypanosoma brucei | metacaspase 5, putative | 0.0052 | 0.0009 | 0.059 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Mycobacterium ulcerans | putative regulatory protein | 0.0042 | 0.0003 | 0.0228 |
Toxoplasma gondii | alpha/beta hydrolase fold domain-containing protein | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0084 | 0.0027 | 0.1814 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0137 | 0.0057 | 0.0057 |
Trypanosoma brucei | monoglyceride lipase, putative | 0.0084 | 0.0027 | 0.1815 |
Trypanosoma cruzi | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0302 | 0.0149 | 1 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.7812 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0102 | 0.0037 | 0.2478 |
Leishmania major | hypothetical protein, conserved | 0.0302 | 0.0149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0007 | 0.0007 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0149 | 0.0064 | 0.4252 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0043 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Probable esterase LipC | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0052 | 0.0009 | 0.0589 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0052 | 0.0009 | 0.0589 |
Leishmania major | ecotin, putative | 0.0302 | 0.0149 | 1 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0043 | 0.0004 | 0.0004 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0061 | 0.0014 | 0.0014 |
Mycobacterium tuberculosis | Probable non lipolytic carboxylesterase NlhH | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0048 | 0.0007 | 0.0007 |
Trypanosoma brucei | metacaspase MCA3 | 0.0052 | 0.0009 | 0.059 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0004 | 0.0004 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0114 | 0.0044 | 0.0044 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0004 | 0.027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0302 | 0.0149 | 1 |
Echinococcus granulosus | caspase 2 | 0.01 | 0.0036 | 0.0036 |
Schistosoma mansoni | tyrosinase precursor | 0.0089 | 0.003 | 0.003 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0302 | 0.0149 | 1 |
Mycobacterium tuberculosis | Possible esterase LipW | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0004 | 0.0004 |
Trypanosoma brucei | Metacaspase-4 | 0.0052 | 0.0009 | 0.059 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0001 | 0.0227 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0061 | 0.0014 | 0.0014 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0043 | 0.0004 | 0.5 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0048 | 0.0007 | 0.0007 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0137 | 0.0057 | 0.379 |
Mycobacterium ulcerans | membrane-bound esterase LipM | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0061 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0014 | 0.0014 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0052 | 0.0009 | 0.059 |
Mycobacterium tuberculosis | Putative acetyl hydrolase MbtJ | 0.0302 | 0.0149 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0084 | 0.0027 | 0.1814 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0001 | 0.0041 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0043 | 0.0004 | 0.027 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0006 | 0.0006 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0021 | 0.139 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0137 | 0.0057 | 0.0057 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0084 | 0.0027 | 0.1814 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0123 | 0.0049 | 0.0049 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0004 | 0.027 |
Onchocerca volvulus | 0.0089 | 0.003 | 0.1819 | |
Echinococcus multilocularis | transfer RNA-Lys | 0.0042 | 0.0003 | 0.0003 |
Brugia malayi | Hypothetical tyrosinase-like protein C02C2.1 in chromosome III | 0.0089 | 0.003 | 0.2004 |
Mycobacterium ulcerans | esterase LipC | 0.0302 | 0.0149 | 1 |
Echinococcus multilocularis | caspase 8 | 0.0052 | 0.0009 | 0.0009 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0006 | 0.0006 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0006 | 0.0006 |
Plasmodium vivax | PST-A protein | 0.0084 | 0.0027 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0021 | 0.139 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Rate of hydrolysis (binding) | = 3.43 nM min-1 mg-1 | Tested for hydrolysis by rat brain microsomal anandamide amidohydrolase (AAH). | ChEMBL. | 10072686 |
Rate of hydrolysis (binding) | = 3.43 nM min-1 mg-1 | Tested for hydrolysis by rat brain microsomal anandamide amidohydrolase (AAH). | ChEMBL. | 10072686 |
Relative rate of hydrolysis (binding) | = 264.2 % | Tested for hydrolysis by rat brain microsomal anandamide amidohydrolase (AAH). | ChEMBL. | 10072686 |
Relative rate of hydrolysis (binding) | = 264.2 % | Tested for hydrolysis by rat brain microsomal anandamide amidohydrolase (AAH). | ChEMBL. | 10072686 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.