Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | titin | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | titin | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Lethal protein 805 | 0.0378 | 0.586 | 1 |
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0378 | 0.586 | 0.5 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | Netrin receptor DCC | 0.0378 | 0.586 | 0.586 |
Brugia malayi | myotactin form A | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | myosin-binding protein-related | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | hypothetical protein | 0.0378 | 0.586 | 0.586 |
Trypanosoma brucei | Fibronectin type III domain containing protein, putative | 0.0378 | 0.586 | 0.5 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0378 | 0.586 | 0.5 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Schistosoma mansoni | tripartite motif protein trim9 | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0378 | 0.586 | 0.586 |
Brugia malayi | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Brugia malayi | Lethal protein 805 | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | usherin | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 32 | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | nephrin | 0.0378 | 0.586 | 0.586 |
Trypanosoma cruzi | Fibronectin type III domain containing protein, putative | 0.0378 | 0.586 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | Down syndrome cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | usherin | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0378 | 0.586 | 1 |
Brugia malayi | SPRY domain containing protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus granulosus | G1Y162 protein | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | myotactin form A | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | nephrin | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | hypothetical protein | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0489 | 1 | 1 |
Echinococcus granulosus | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | Netrin receptor DCC | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0378 | 0.586 | 1 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | titin | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus granulosus | Phosphotidylinositol phosphatase PTPRQ | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | titin | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | anosmin 1 | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | EG95 | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | factor for adipocyte differentiation | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | neuroglian | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Schistosoma mansoni | nephrin | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | projectin | 0.0378 | 0.586 | 1 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 30. | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | Phosphotidylinositol phosphatase PTPRQ | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | Netrin receptor DCC | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | Netrin receptor DCC | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | titin | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | neuroglian | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | ephrin receptor | 0.0489 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | contactin | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0378 | 0.586 | 0.586 |
Brugia malayi | hypothetical protein | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | hemicentin | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Brugia malayi | protein unc-22 | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | titin | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | Fibronectin, type III | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | Fibronectin type III | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0378 | 0.586 | 0.586 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | Phosphotidylinositol phosphatase PTPRQ | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | lethal protein 805 | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Echinococcus granulosus | Down syndrome cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Echinococcus multilocularis | titin | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | cell adhesion molecule | 0.0378 | 0.586 | 0.586 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 0.586 |
Brugia malayi | myotactin form B | 0.0378 | 0.586 | 1 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0378 | 0.586 | 0.586 |
Leishmania major | hypothetical protein, conserved | 0.0378 | 0.586 | 0.5 |
Echinococcus granulosus | fibronectin type III domain-containing protein | 0.0378 | 0.586 | 0.586 |
Schistosoma mansoni | neuroglian | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.586 | 1 |
Onchocerca volvulus | 0.0378 | 0.586 | 0.5 | |
Echinococcus multilocularis | roundabout 2 | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | UNCoordinated family member | 0.0378 | 0.586 | 1 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0378 | 0.586 | 0.586 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0378 | 0.586 | 1 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0378 | 0.586 | 1 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0378 | 0.586 | 0.586 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Latency time (functional) | = 37 s | Compound was evaluated for brain targeted delivery system by Tail flick latency as an index of spinal cord mediated analgesia in rats | ChEMBL. | 9748352 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.