Detailed information for compound 505534

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1626.74 | Formula: C79H95N13O23S
  • H donors: 14 H acceptors: 20 LogP: 1.98 Rotable bonds: 45
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC(=O)CC[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCCCC1C(=O)N1C[C@H](C[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCC(=O)O)CCC(=O)O)O/N=C\C(=C\c1ccccc1)\C)C)[C@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)CCCCNC(=S)Nc1ccc2c(c1)C1(OC2=O)c2ccc(cc2Oc2c1ccc(c2)O)O
  • InChi: 1S/C79H95N13O23S/c1-42(35-45-13-5-4-6-14-45)40-82-115-49-39-60(72(107)86-55(26-29-65(99)100)69(104)85-54(68(80)103)25-28-64(97)98)92(41-49)76(111)59-15-8-10-32-91(59)74(109)43(2)83-73(108)67(44(3)93)88-71(106)58-17-12-34-90(58)75(110)56(27-30-66(101)102)87-70(105)57-16-11-33-89(57)63(96)18-7-9-31-81-78(116)84-46-19-22-50-53(36-46)79(114-77(50)112)51-23-20-47(94)37-61(51)113-62-38-48(95)21-24-52(62)79/h4-6,13-14,19-24,35-38,40,43-44,49,54-60,67,93-95H,7-12,15-18,25-34,39,41H2,1-3H3,(H2,80,103)(H,83,108)(H,85,104)(H,86,107)(H,87,105)(H,88,106)(H,97,98)(H,99,100)(H,101,102)(H2,81,84,116)/b42-35+,82-40-/t43-,44+,49-,54-,55-,56-,57-,58-,59?,60-,67-/m0/s1
  • InChiKey: GSQHNYJFLXGIRF-ABDHXIOESA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0066 0.1614 0.1555
Loa Loa (eye worm) hypothetical protein 0.0085 0.236 0.2306
Schistosoma mansoni hypothetical protein 0.0176 0.5823 0.5715
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0252 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0252 0.0182
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0084 0.2303 0.3682
Brugia malayi nuclear receptor NHR-88 0.003 0.0252 0.0182
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0095 0.2725 0.2538
Loa Loa (eye worm) hypothetical protein 0.0082 0.2218 0.2163
Echinococcus granulosus fructose bisphosphate aldolase class I 0.0095 0.2725 0.4441
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0057 0.128 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0803 0.2948
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0088 0.2452 0.3949
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0095 0.2725 0.4441
Schistosoma mansoni jun-related protein 0.0071 0.1825 0.1614
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0084 0.2303 0.3682
Mycobacterium tuberculosis Conserved protein 0.0039 0.0576 0.0368
Echinococcus multilocularis geminin 0.0176 0.5823 1
Leishmania major hypothetical protein, conserved 0.0039 0.0576 0.0501
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0031 0.0273 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.056 0.0493
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0095 0.2725 0.4441
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0252 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0252 0.0182
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0256 0.0187
Echinococcus multilocularis lamin dm0 0.003 0.0256 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Loa Loa (eye worm) hypothetical protein 0.003 0.0235 0.0166
Loa Loa (eye worm) beta-lactamase 0.0039 0.0576 0.0509
Loa Loa (eye worm) glutaminase 2 0.0286 1 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0087 0.242 0.2557
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0576 0.0509
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0803 0.0241
Loa Loa (eye worm) hypothetical protein 0.0084 0.2303 0.2248
Onchocerca volvulus 0.0069 0.1733 0.7532
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0443 0.0352
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0045 0.0806 0.0647
Brugia malayi beta-lactamase 0.0039 0.0576 0.0509
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0031 0.0273 0.0204
Trypanosoma brucei squalene synthase, putative 0.0262 0.9094 1
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0539 0.0294
Schistosoma mansoni DNA polymerase eta 0.0031 0.0273 0.0022
Trypanosoma brucei DNA polymerase IV, putative 0.0087 0.242 0.2557
Toxoplasma gondii fructose-bisphosphate aldolase, putative 0.0095 0.2725 1
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0252 0.0182
Echinococcus granulosus Squalene phytoene synthase 0.0082 0.2218 0.353
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.4882 0.4845
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0443 0.0352
Brugia malayi fructose-bisphosphate aldolase 1 0.0095 0.2725 0.2674
Trypanosoma cruzi DNA polymerase kappa, putative 0.0087 0.242 0.2557
Schistosoma mansoni lamin 0.003 0.0256 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.1233 0.1171
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0576 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.0035 0.0443 0.0352
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0252 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Schistosoma mansoni hypothetical protein 0.0071 0.1825 0.1614
Brugia malayi steroid hormone receptor 0.003 0.0252 0.0182
Brugia malayi ecdysteroid receptor 0.003 0.0252 0.0182
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0252 0.0182
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0095 0.2725 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0576 0.0368
Echinococcus multilocularis jun protein 0.0088 0.2452 0.3949
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0252 0.0182
Echinococcus granulosus geminin 0.0176 0.5823 1
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0576 0.0368
Echinococcus multilocularis Squalene phytoene synthase 0.0082 0.2218 0.353
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0576 0.0368
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0576 0.0501
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Schistosoma mansoni hypothetical protein 0.0082 0.2218 0.2018
Trypanosoma brucei DNA polymerase eta, putative 0.0031 0.0273 0.0163
Trypanosoma cruzi phytoene synthase, putative 0.0082 0.2218 0.2332
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.4882 0.8311
Onchocerca volvulus 0.003 0.0256 0.0024
Echinococcus multilocularis musashi 0.003 0.0256 0.0008
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0095 0.2725 0.2897
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0252 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Toxoplasma gondii ABC1 family protein 0.0039 0.0576 0.2115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0252 0.0182
Brugia malayi beta-lactamase family protein 0.0039 0.0576 0.0509
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0095 0.2725 0.4441
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0252 0.0182
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0576 0.0501
Trichomonas vaginalis glutaminase, putative 0.0286 1 1
Echinococcus multilocularis dna polymerase eta 0.0031 0.0273 0.0039
Loa Loa (eye worm) follicle stimulating hormone receptor 0.026 0.8995 0.8988
Loa Loa (eye worm) acetyltransferase 0.0152 0.4882 0.4845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0252 0.0182
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0803 0.0991
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0088 0.2452 0.3949
Schistosoma mansoni hypothetical protein 0.0038 0.056 0.0316
Echinococcus multilocularis lamin 0.003 0.0256 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.1614 0.1658
Loa Loa (eye worm) hypothetical protein 0.0031 0.0273 0.0204
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0095 0.2725 0.4441
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Onchocerca volvulus 0.0039 0.0576 0.1652
Loa Loa (eye worm) intermediate filament protein 0.003 0.0256 0.0187
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0031 0.0273 0.0022
Schistosoma mansoni glutaminase 0.0286 1 1
Echinococcus multilocularis fructose 1,6 bisphosphate aldolase 0.0095 0.2725 0.4441
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0252 0.0182
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0576 0.0368
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0082 0.2218 1
Schistosoma mansoni fructose 16-bisphosphate aldolase 0.0095 0.2725 0.2538
Schistosoma mansoni tsg101-related 0.007 0.1768 0.1555
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0252 0.0182
Toxoplasma gondii fructose-1,6-bisphosphate aldolase 0.0095 0.2725 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0576 0.0333
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0252 0.0182
Brugia malayi beta-lactamase family protein 0.0039 0.0576 0.0509
Schistosoma mansoni tsg101-related 0.0057 0.128 0.1055
Trypanosoma brucei fructose-bisphosphate aldolase, glycosomal, putative 0.0095 0.2725 0.2897
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0576 0.0368
Onchocerca volvulus 0.003 0.0256 0.0024
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0576 0.0583
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0256 0.0187
Echinococcus multilocularis dna polymerase kappa 0.0087 0.242 0.3892
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0576 0.0509
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Leishmania major DNA polymerase kappa, putative 0.0045 0.0806 0.0757
Trypanosoma brucei DNA polymerase IV, putative 0.0087 0.242 0.2557
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Leishmania major hypothetical protein, conserved 0.0082 0.2218 0.2332
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.4719 0.802
Echinococcus granulosus fructose 16 bisphosphate aldolase 0.0095 0.2725 0.4441
Brugia malayi ImpB/MucB/SamB family protein 0.0031 0.0273 0.0204
Brugia malayi nuclear hormone receptor 0.003 0.0252 0.0182
Brugia malayi hypothetical protein 0.0069 0.1733 0.1674
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0252 0.0182
Mycobacterium ulcerans DNA polymerase IV 0.0087 0.242 0.1956
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0095 0.2725 0.2897
Plasmodium vivax fructose 1,6-bisphosphate aldolase, putative 0.0095 0.2725 1
Leishmania major fructose-1,6-bisphosphate aldolase 0.0095 0.2725 0.2897
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0803 0.1056
Trypanosoma brucei DNA polymerase kappa, putative 0.0045 0.0806 0.0757
Mycobacterium ulcerans phytoene synthase, CrtB 0.0082 0.2218 0.1742
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0095 0.2725 0.2897
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0252 0.0182
Brugia malayi hypothetical protein 0.0084 0.2303 0.2248
Schistosoma mansoni hypothetical protein 0.0176 0.5823 0.5715
Onchocerca volvulus 0.0039 0.0576 0.1652
Schistosoma mansoni intermediate filament proteins 0.003 0.0256 0.0005
Entamoeba histolytica hypothetical protein 0.0038 0.0539 0.2636
Loa Loa (eye worm) hypothetical protein 0.003 0.0252 0.0182
Loa Loa (eye worm) glutaminase 0.0286 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0087 0.242 0.1956
Mycobacterium tuberculosis Conserved protein 0.0039 0.0576 0.0368
Entamoeba histolytica hypothetical protein 0.0038 0.0539 0.2636
Trypanosoma brucei DNA polymerase IV, putative 0.0073 0.1887 0.1963
Brugia malayi intermediate filament protein 0.003 0.0256 0.0187
Echinococcus multilocularis fructose bisphosphate aldolase class I 0.0095 0.2725 0.4441
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0252 0.0182
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0082 0.2218 0.2362
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.1233 0.1171
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0252 0.0182
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0662 0.3861
Leishmania major squalene synthase, putative 0.0262 0.9094 1
Brugia malayi bZIP transcription factor family protein 0.0088 0.2452 0.2398
Plasmodium falciparum fructose-bisphosphate aldolase 0.0095 0.2725 1
Mycobacterium ulcerans glutaminase 0.0286 1 1
Brugia malayi polk-prov protein 0.0066 0.1614 0.1555
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Echinococcus granulosus intermediate filament protein 0.003 0.0256 0.0008
Echinococcus granulosus lamin 0.003 0.0256 0.0008
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0539 0.0515
Trichomonas vaginalis DNA polymerase eta, putative 0.0087 0.242 0.1956
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0576 0.0583
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0045 0.0806 0.0757
Loa Loa (eye worm) hypothetical protein 0.003 0.0256 0.0187
Entamoeba histolytica hypothetical protein 0.0038 0.0539 0.2636
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0576 0.0368
Mycobacterium leprae Probable lipase LipE 0.0039 0.0576 0.5
Trichomonas vaginalis hypothetical protein 0.0041 0.0662 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0087 0.242 0.2557
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Echinococcus granulosus lamin dm0 0.003 0.0256 0.0008
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.4882 0.4749
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0252 0.0182
Trypanosoma cruzi fructose-bisphosphate aldolase, glycosomal, putative 0.0095 0.2725 0.2897
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0576 0.0501
Echinococcus granulosus dna polymerase eta 0.0031 0.0273 0.0039
Echinococcus granulosus dna polymerase kappa 0.0087 0.242 0.3892
Schistosoma mansoni hypothetical protein 0.0038 0.0539 0.0294
Echinococcus granulosus jun protein 0.0088 0.2452 0.3949
Loa Loa (eye worm) hypothetical protein 0.0039 0.0576 0.0509
Schistosoma mansoni tsg101-related 0.007 0.1768 0.1555
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0803 0.2948
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.1233 0.1171
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0539 0.0515
Entamoeba histolytica hypothetical protein 0.0038 0.0539 0.2636
Trypanosoma brucei unspecified product 0.0073 0.1887 0.1963
Onchocerca volvulus 0.0039 0.0576 0.1652
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0031 0.0273 0.0039
Trypanosoma cruzi squalene synthase, putative 0.0262 0.9094 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0576 0.0368
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0576 0.0333
Brugia malayi ImpB/MucB/SamB family protein 0.0031 0.0273 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0252 0.0182
Loa Loa (eye worm) hypothetical protein 0.0056 0.1233 0.1171
Loa Loa (eye worm) fructose-bisphosphate aldolase 1 0.0095 0.2725 0.2674
Loa Loa (eye worm) hypothetical protein 0.0038 0.056 0.0493
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0087 0.242 0.1956
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.242 0.2557
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0252 0.0182
Brugia malayi follicle stimulating hormone receptor 0.026 0.8995 0.8988
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0273 0.0163
Leishmania major DNA polymerase eta, putative 0.0031 0.0273 0.0163
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0803 0.0241
Schistosoma mansoni terminal deoxycytidyl transferase 0.0031 0.0273 0.0022
Trypanosoma cruzi DNA polymerase kappa, putative 0.0087 0.242 0.2557
Trypanosoma cruzi squalene synthase, putative 0.0262 0.9094 1
Brugia malayi fructose-bisphosphate aldolase 2 0.0095 0.2725 0.2674
Schistosoma mansoni lamin 0.003 0.0256 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0066 0.1614 0.1658
Brugia malayi hypothetical protein 0.0038 0.0539 0.0471
Mycobacterium tuberculosis Conserved protein 0.0039 0.0576 0.0368
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0247 0.8508 1
Giardia lamblia DINP protein human, muc B family 0.0045 0.0806 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0252 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0252 0.0182
Loa Loa (eye worm) fructose-bisphosphate aldolase 2 0.0095 0.2725 0.2674

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 58 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557
IC50 (binding) = 58 uM Binding affinity to Tsg101 (unknown origin) ChEMBL. 18083557

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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