Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0108 | 0.01 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.0387 | 0.0387 |
Echinococcus granulosus | methionyl aminopeptidase 2 | 0.0976 | 1 | 1 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Onchocerca volvulus | 0.0035 | 0.0008 | 0.0008 | |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0261 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma brucei | methionine aminopeptidase 2, putative | 0.0976 | 1 | 1 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.0387 | 0.0379 |
Plasmodium vivax | proliferation-associated protein 2g4, putative | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium tuberculosis | Dipeptidase PepE | 0.0121 | 0.0925 | 0.4607 |
Chlamydia trachomatis | aminopeptidase P | 0.0121 | 0.0925 | 0.5 |
Leishmania major | methionine aminopeptidase 2, putative | 0.0976 | 1 | 1 |
Loa Loa (eye worm) | metallopeptidase family M24 containing protein | 0.0121 | 0.0925 | 0.0925 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0925 | 0.0925 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0008 | 0.0008 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | methionine aminopeptidase type I | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Onchocerca volvulus | Dipeptidase C homolog | 0.0121 | 0.0925 | 0.0925 |
Brugia malayi | DNA-binding protein, 42 kDa containing protein | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0925 | 0.0925 |
Plasmodium vivax | FACT complex subunit SPT16, putative | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Leishmania major | transcription factor-like protein | 0.0121 | 0.0925 | 0.0918 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | methionine aminopeptidase, type I | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0008 | 0.0008 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | Proliferation associated protein 2G4 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0121 | 0.0925 | 0.0925 |
Toxoplasma gondii | methionine aminopeptidase | 0.0121 | 0.0925 | 0.0918 |
Plasmodium vivax | methionine aminopeptidase 2, putative | 0.0976 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0108 | 0.01 |
Loa Loa (eye worm) | DNA-binding protein | 0.0121 | 0.0925 | 0.0925 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0121 | 0.0925 | 1 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0108 | 0.01 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0108 | 0.01 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0261 | 0.0254 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0976 | 1 | 1 |
Mycobacterium leprae | Probable cytoplasmic peptidase PepQ | 0.0121 | 0.0925 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0078 | 0.0461 | 0.0454 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0768 | 0.7791 | 0.7789 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0135 | 0.0127 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0121 | 0.0925 | 0.4607 |
Trypanosoma brucei | Facilitates chromatin transcription complex subunit spt16 | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0387 | 0.0379 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0135 | 0.0127 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | Xaa Pro aminopeptidase 3 | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0108 | 0.01 |
Loa Loa (eye worm) | initiation factor 2-associated protein | 0.0976 | 1 | 1 |
Echinococcus multilocularis | Proliferation associated protein 2G4 | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0387 | 0.0379 |
Plasmodium falciparum | methionine aminopeptidase 2 | 0.0976 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase 2, putative | 0.0976 | 1 | 1 |
Trypanosoma cruzi | Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0108 | 0.0108 |
Onchocerca volvulus | 0.0121 | 0.0925 | 0.0925 | |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.2765 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0121 | 0.0925 | 0.0918 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.0387 | 0.0379 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | Xaa-Pro dipeptidase (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.0387 | 0.0387 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.0461 | 0.0454 |
Onchocerca volvulus | Methionine aminopeptidase 2 homolog | 0.0976 | 1 | 1 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0121 | 0.0925 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium tuberculosis | Probable cytoplasmic peptidase PepQ | 0.0121 | 0.0925 | 0.4607 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.01 | 0.0092 |
Trypanosoma cruzi | aminopeptidase P1, putative | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0121 | 0.0925 | 0.4607 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0387 | 0.0379 |
Brugia malayi | RNA binding protein | 0.007 | 0.0387 | 0.0379 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.0461 | 0.0454 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.0387 | 0.0387 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0121 | 0.0925 | 0.0918 |
Brugia malayi | TAR-binding protein | 0.007 | 0.0387 | 0.0379 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.01 | 0.01 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0976 | 1 | 1 |
Echinococcus granulosus | Xaa Pro aminopeptidase 3 | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.0461 | 0.0454 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0121 | 0.0925 | 0.0918 |
Treponema pallidum | aminopeptidase P | 0.0121 | 0.0925 | 0.5 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma cruzi | Metallopeptidase family M24, putative | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0768 | 0.7791 | 0.7789 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium ulcerans | aminopeptidase | 0.0121 | 0.0925 | 1 |
Schistosoma mansoni | aminopeptidase P1 (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0121 | 0.0925 | 0.5 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0121 | 0.0925 | 1 |
Onchocerca volvulus | FACT complex subunit SPT16 homolog | 0.0121 | 0.0925 | 0.0925 |
Trypanosoma brucei | metallo-peptidase, Clan MG, Family M24 | 0.0976 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0387 | 0.0379 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | FACT complex subunit SPT16 | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0387 | 0.0379 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0121 | 0.0925 | 1 |
Toxoplasma gondii | peptidase D, putative | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | proliferation-associated protein 2G4 38kDa (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.0461 | 0.0454 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0925 | 0.0925 |
Toxoplasma gondii | creatinase domain-containing protein | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.2765 |
Leishmania major | hypothetical protein, conserved | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium ulcerans | dipeptidase PepE | 0.0121 | 0.0925 | 1 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.0461 | 0.0454 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.0461 | 0.0454 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.0254 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.0461 | 0.0454 |
Schistosoma mansoni | peptidase | 0.0121 | 0.0925 | 0.0918 |
Toxoplasma gondii | methionine aminopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.0135 | 0.0135 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.2765 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0222 | 0.1998 | 1 |
Onchocerca volvulus | 0.0035 | 0.0008 | 0.0008 | |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | methionyl aminopeptidase 2 (M24 family) | 0.0976 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0078 | 0.0461 | 0.0461 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0121 | 0.0925 | 0.5 |
Onchocerca volvulus | 0.0035 | 0.0008 | 0.0008 | |
Trypanosoma brucei | Metallopeptidase family M24, putative | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma cruzi | aminopeptidase P, putative | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24 | 0.0976 | 1 | 1 |
Toxoplasma gondii | proliferation-associated protein 2G4, putative | 0.0121 | 0.0925 | 0.0918 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0976 | 1 | 1 |
Mycobacterium ulcerans | cytoplasmic peptidase PepQ | 0.0121 | 0.0925 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0261 | 0.0254 |
Wolbachia endosymbiont of Brugia malayi | Xaa-Pro aminopeptidase | 0.0121 | 0.0925 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.0254 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0121 | 0.0925 | 0.0918 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0121 | 0.0925 | 0.0918 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0121 | 0.0925 | 0.5 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0976 | 1 | 1 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0121 | 0.0925 | 0.0918 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0121 | 0.0925 | 0.0918 |
Brugia malayi | chromobox protein homolog 3 | 0.0043 | 0.01 | 0.0092 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0108 | 0.01 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.0461 | 0.0454 |
Echinococcus multilocularis | methionyl aminopeptidase 2 | 0.0976 | 1 | 1 |
Schistosoma mansoni | chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0108 | 0.01 |
Plasmodium vivax | methionine aminopeptidase 1c, putative | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.1274 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Echinococcus granulosus | xaa Pro dipeptidase | 0.0121 | 0.0925 | 0.0918 |
Toxoplasma gondii | transcriptional elongation factor FACT140 | 0.0121 | 0.0925 | 0.0918 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0108 | 0.01 |
Echinococcus multilocularis | xaa Pro dipeptidase | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0261 | 0.0254 |
Plasmodium vivax | peptidase, putative | 0.0121 | 0.0925 | 0.0918 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0768 | 0.7791 | 0.7789 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0976 | 1 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Entamoeba histolytica | methionine aminopeptidase, putative | 0.0976 | 1 | 1 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Leishmania major | aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24 | 0.0121 | 0.0925 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0008 | 0.0008 |
Echinococcus granulosus | FACT complex subunit SPT16 | 0.0121 | 0.0925 | 0.0918 |
Mycobacterium ulcerans | dipeptidase | 0.0121 | 0.0925 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.0387 | 0.0379 |
Trichomonas vaginalis | Clan MG, familly M24, aminopeptidase P-like metallopeptidase | 0.0121 | 0.0925 | 0.0918 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.01 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.01 | 0.01 |
Giardia lamblia | Methionine aminopeptidase | 0.0976 | 1 | 1 |
Trypanosoma cruzi | Metallopeptidase family M24, putative | 0.0121 | 0.0925 | 0.0918 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.