Detailed information for compound 64072

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 821.019 | Formula: C41H57FN10O5S
  • H donors: 8 H acceptors: 6 LogP: 4.22 Rotable bonds: 25
    Rule of 5 violations (Lipinski): 3
  • SMILES: NC(=NCCC[C@@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)NC(=O)[C@@H](NC(=O)c1csc(n1)[C@@H](NC(=O)C(C(C)C)N)Cc1ccc(cc1)F)CC1CCCCC1)N
  • InChi: 1S/C41H57FN10O5S/c1-24(2)34(43)39(57)51-32(22-27-15-17-28(42)18-16-27)40-52-33(23-58-40)38(56)50-31(21-26-12-7-4-8-13-26)37(55)48-29(14-9-19-47-41(45)46)36(54)49-30(35(44)53)20-25-10-5-3-6-11-25/h3,5-6,10-11,15-18,23-24,26,29-32,34H,4,7-9,12-14,19-22,43H2,1-2H3,(H2,44,53)(H,48,55)(H,49,54)(H,50,56)(H,51,57)(H4,45,46,47)/t29-,30-,31-,32-,34?/m0/s1
  • InChiKey: LQJFCDFVAFXCDU-BHBZANMBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor II (thrombin) receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0007
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0024 0.0115 0.0132
Schistosoma mansoni hypothetical protein 0.0015 0.0013 0.0015
Echinococcus granulosus hypothetical protein 0.0021 0.0077 0.0088
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0111 0.1152 0.4899
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0574 0.0657
Schistosoma mansoni biogenic amine receptor 0.0021 0.0077 0.0088
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0075 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0036
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.1042 0.1193
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0479 0.5542 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0077 0.0081
Brugia malayi Thioredoxin reductase 0.0049 0.041 0.046
Brugia malayi GnHR receptor homolog 0.0021 0.0077 0.0082
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Plasmodium vivax vivapain-3 0.0255 0.2866 0.5165
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0109 0.0183
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0077 0.0088
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Giardia lamblia Cathepsin B precursor 0.0264 0.2979 0.8254
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0075 0.0086
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0042 0.0042
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0069 0.0652 0.0746
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0075 0.0086
Plasmodium vivax vivapain-1 0.0255 0.2866 0.5165
Onchocerca volvulus Neuropeptide F receptor homolog 0.0021 0.0077 0.0131
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Echinococcus granulosus cathepsin L cysteine protease 0.0255 0.2866 0.328
Schistosoma mansoni lamin 0.0029 0.0178 0.0204
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trypanosoma cruzi cysteine peptidase, putative 0.0853 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0326 0.3718 0.6704
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0077 0.0088
Onchocerca volvulus 0.0021 0.0077 0.0131
Brugia malayi MH2 domain containing protein 0.0033 0.0221 0.0245
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0029 0.0175 0.0193
Onchocerca volvulus 0.0021 0.0077 0.0131
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0077 0.0081
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0075 0.008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus multilocularis sodium leak channel non selective protein 0.0024 0.0115 0.0121
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0075 0.0086
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0136 0.0232
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0574 0.3402
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0077 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0264 0.2979 0.537
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0034 0.0039
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0077 0.0082
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0075 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Brugia malayi steroid hormone receptor 0.0021 0.0075 0.008
Echinococcus granulosus transient receptor potential gamma protein 0.0024 0.0115 0.0132
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0041 0.0317 0.0354
Brugia malayi larval opioid receptor 0.0021 0.0077 0.0082
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0591 0.0665
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Brugia malayi PHD-finger family protein 0.0028 0.0167 0.0184
Echinococcus multilocularis cathepsin b 0.0627 0.7306 0.7678
Echinococcus granulosus dnaJ subfamily B 0.0416 0.4796 0.5489
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0138 0.0145
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0264 0.2979 0.2974
Echinococcus granulosus sex peptide receptor 0.0021 0.0077 0.0088
Schistosoma mansoni importin beta-1 0.0029 0.0175 0.02
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0136 0.0128
Brugia malayi TATA binding protein associated factor 0.0015 0.0008 0.0004
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0591 0.1059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0024 0.0115 0.0132
Echinococcus granulosus calpain 7 C02 family 0.0022 0.009 0.0103
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Trypanosoma brucei calpain-like protein, putative 0.0022 0.009 0.0082
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0497 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0024 0.0115 0.0121
Brugia malayi hypothetical protein 0.0017 0.0028 0.0026
Echinococcus multilocularis hyperpolarization activated cyclic 0.0028 0.0162 0.0171
Onchocerca volvulus 0.0073 0.0702 0.1259
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.002 0.0012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0005 0.0005
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0479 0.5542 1
Plasmodium falciparum serine repeat antigen 1 0.0102 0.1042 0.1869
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0109 0.0183
Onchocerca volvulus Eukaryotic initiation factor 4A homolog 0.0025 0.0126 0.0218
Echinococcus multilocularis cathepsin L 0.0102 0.1042 0.1095
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0024 0.0115 0.0121
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0077 0.0081
Brugia malayi intermediate filament protein 0.0029 0.0178 0.0197
Loa Loa (eye worm) hypothetical protein 0.0018 0.0049 0.005
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0075 0.008
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.009 0.0103
Brugia malayi Papain family cysteine protease containing protein 0.0479 0.5542 0.6284
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0102 0.1042 0.1178
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0627 0.7306 0.7304
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0062 0.0065
Loa Loa (eye worm) ryanodine receptor 0.0024 0.0115 0.0126
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0075 0.0086
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0162 0.0279
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0381 0.0373
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0077 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0269 0.0261
Onchocerca volvulus 0.0021 0.0077 0.0131
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.1042 0.2831
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0416 0.0476
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0015 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0075 0.008
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0109 0.0183
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0025 0.0126 0.0118
Brugia malayi Serotonin receptor 0.0021 0.0077 0.0082
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.041 0.0726
Giardia lamblia Cathepsin B precursor 0.0264 0.2979 0.8254
Echinococcus granulosus sodium channel protein 0.0024 0.0115 0.0132
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.0115 0.0132
Entamoeba histolytica cysteine proteinase, putative 0.0326 0.3718 0.6704
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Onchocerca volvulus Chorion peroxidase homolog 0.0064 0.0591 0.1059
Brugia malayi beta-lactamase family protein 0.0073 0.0702 0.0791
Echinococcus multilocularis calpain 0.0022 0.009 0.0094
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.006 0.0549 0.0628
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0031 0.0023
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0178 0.0197
Echinococcus multilocularis voltage dependent calcium channel 0.0024 0.0115 0.0121
Onchocerca volvulus Peroxidase homolog 0.0064 0.0591 0.1059
Echinococcus granulosus cathepsin l1 0.0479 0.5542 0.6342
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0102 0.1042 0.1193
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0479 0.0503
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni zinc finger protein 0.0023 0.0103 0.0118
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Onchocerca volvulus 0.0021 0.0075 0.0127
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0268 0.047
Plasmodium vivax unspecified product 0.0255 0.2866 0.5165
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0269 0.0261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0127 0.0215
Entamoeba histolytica protein kinase, putative 0.0015 0.0012 0.0007
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0077 0.0081
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.2052 0.2323
Trypanosoma cruzi cysteine peptidase, putative 0.0255 0.2866 0.2861
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0143 0.0157
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0221 0.0245
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0702 0.0791
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.0115 0.0121
Onchocerca volvulus 0.0057 0.0514 0.0919
Onchocerca volvulus Cathepsin L homolog 0.0102 0.1042 0.1874
Loa Loa (eye worm) hypothetical protein 0.0046 0.0379 0.0424
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0077 0.0082
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0702 0.0694
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0591 0.0665
Echinococcus multilocularis eukaryotic initiation factor 4A 0.0025 0.0126 0.0132
Brugia malayi Muscleblind-like protein 0.0162 0.1759 0.1991
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0075 0.0086
Loa Loa (eye worm) voltage-gated potassium channel 0.0024 0.0115 0.0126
Brugia malayi Cathepsin L-like cysteine proteinase 0.0326 0.3718 0.4214
Trypanosoma cruzi major cysteine proteinase, putative 0.0475 0.5501 0.5497
Giardia lamblia Hypothetical protein 0.0102 0.1042 0.2831
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.006 0.0549 0.0628
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0102 0.1042 0.2831
Echinococcus granulosus calcium activated potassium channel 0.0024 0.0115 0.0132
Schistosoma mansoni calcium-activated potassium channel 0.0024 0.0115 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Giardia lamblia Cathepsin B precursor 0.0264 0.2979 0.8254
Onchocerca volvulus 0.0021 0.0077 0.0131
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0075 0.0086
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0702 0.0737
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0259 0.0273
Loa Loa (eye worm) nuclear factor I 0.0018 0.0046 0.0047
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0075 0.008
Schistosoma mansoni hypothetical protein 0.0082 0.0803 0.0919
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Brugia malayi cathepsin B-like cysteine proteinase 0.0627 0.7306 0.8287
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0077 0.0088
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Trypanosoma brucei calpain-like protein, putative 0.0022 0.009 0.0082
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0574 0.3402
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Giardia lamblia Cathepsin B precursor 0.0102 0.1042 0.2831
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0077 0.0088
Brugia malayi Peptidase family M1 containing protein 0.0015 0.0008 0.0004
Trypanosoma brucei kinesin, putative 0.0015 0.0012 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Leishmania major cathepsin L-like protease 0.0479 0.5542 0.5538
Trypanosoma brucei cytochrome P450, putative 0.0016 0.002 0.0012
Echinococcus granulosus cathepsin b 0.0627 0.7306 0.8361
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.0115 0.0132
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.1042 0.2831
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0178 0.0197
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0075 0.0079
Trypanosoma brucei calpain-like protein, putative 0.0022 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0281 0.3177 0.3636
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.0126 0.0118
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1042 0.1869
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0591 0.0665
Mycobacterium ulcerans hypothetical protein 0.0073 0.0702 0.4165
Leishmania major trypanothione reductase 0.0049 0.041 0.0402
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0075 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0077 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0075 0.008
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0136 0.0128
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0024 0.0115 0.0107
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus granulosus calpain 0.0022 0.009 0.0103
Loa Loa (eye worm) hypothetical protein 0.0176 0.1932 0.2188
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0162 0.0186
Brugia malayi Cytochrome P450 family protein 0.0026 0.0143 0.0157
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.0115 0.0132
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.04 0.0714
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0479 0.0538
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.002 0.007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1042 0.1869
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0024 0.0115 0.0126
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0255 0.2866 0.328
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni cathepsin s 0.0153 0.1654 0.1893
Entamoeba histolytica cysteine proteinase, putative 0.0255 0.2866 0.5165
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0497 0.0868
Echinococcus multilocularis conserved hypothetical protein 0.0024 0.0115 0.0121
Brugia malayi Papain family cysteine protease containing protein 0.0255 0.2866 0.3248
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0004
Plasmodium falciparum serine repeat antigen 7 0.0102 0.1042 0.1869
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0036 0.0258 0.0288
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0381 0.0674
Schistosoma mansoni cpg binding protein 0.0062 0.0575 0.0659
Echinococcus multilocularis zinc finger protein 0.0023 0.0103 0.0108
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0077 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0268 0.047
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0102 0.1042 0.1869
Schistosoma mansoni hypothetical protein 0.0082 0.0803 0.0919
Schistosoma mansoni Smad4 0.0033 0.0221 0.0252
Trypanosoma cruzi Aph-1 protein, putative 0.0225 0.2517 0.2511
Echinococcus granulosus tumor protein p63 0.0336 0.3833 0.4387
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0077 0.0088
Echinococcus granulosus ryanodine receptor 44f 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) cathepsin B 0.0264 0.2979 0.3376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0077 0.0088
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0115 0.0194
Loa Loa (eye worm) hypothetical protein 0.0048 0.04 0.0449
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0075 0.0086
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0075 0.0079
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0591 0.0665
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0221 0.0232
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus granulosus snurportin 1 0.0308 0.3507 0.4013
Onchocerca volvulus 0.0479 0.5542 1
Echinococcus granulosus somatostatin receptor 0.0021 0.0077 0.0088
Trypanosoma cruzi kinesin, putative 0.0015 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0077 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0702 0.0486
Leishmania major cathepsin L-like protease 0.0479 0.5542 0.5538
Echinococcus multilocularis geminin 0.0679 0.793 0.8335
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0115 0.0194
Schistosoma mansoni biogenic amine receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0077 0.0081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni vesicular amine transporter 0.0024 0.0115 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Brugia malayi Dopamine receptor protein 2 0.0021 0.0077 0.0082
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0497 0.0559
Brugia malayi Bromodomain containing protein 0.0078 0.0765 0.0863
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Echinococcus multilocularis shaker cognate 0.0024 0.0115 0.0121
Echinococcus granulosus cathepsin b 0.0627 0.7306 0.8361
Giardia lamblia Cathepsin B precursor 0.0102 0.1042 0.2831
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0015 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0069 0.0652 0.1164
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.04 0.042
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0077 0.0082
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0102 0.1042 0.1869
Schistosoma mansoni smad 0.0033 0.0221 0.0252
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.006 0.0549 0.0628
Leishmania major hypothetical protein, conserved 0.0024 0.0115 0.0107
Echinococcus multilocularis sex peptide receptor 0.0021 0.0077 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0162 0.0186
Echinococcus granulosus Smad4 0.0033 0.0221 0.0252
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Trypanosoma brucei Eukaryotic initiation factor 4A-1 0.0025 0.0126 0.0118
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0255 0.2866 0.2861
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.002 0.0017
Loa Loa (eye worm) hypothetical protein 0.0018 0.0046 0.0047
Onchocerca volvulus 0.0326 0.3718 0.6706
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Loa Loa (eye worm) ctsf protein 0.0479 0.5542 0.6284
Brugia malayi Peroxidasin 0.0064 0.0591 0.0665
Schistosoma mansoni voltage-dependent calcium channel 0.0024 0.0115 0.0132
Leishmania major cathepsin L-like protease 0.0853 1 1
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0005 0.0005
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0268 0.047
Onchocerca volvulus 0.0029 0.0178 0.0314
Echinococcus multilocularis transfer RNA-Gly 0.0024 0.0115 0.0121
Mycobacterium leprae Probable lipase LipE 0.0073 0.0702 0.0486
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.04 0.0449
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0381 0.0373
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0497 0.2936
Toxoplasma gondii cathepsin B 0.0264 0.2979 0.537
Brugia malayi Dopamine receptor 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Plasmodium falciparum importin beta, putative 0.0029 0.0175 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Loa Loa (eye worm) ion channel NompC 0.0024 0.0115 0.0126
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0024 0.0115 0.02
Echinococcus multilocularis calcium activated potassium channel 0.0024 0.0115 0.0121
Leishmania major cathepsin L-like protease 0.0479 0.5542 0.5538
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.7306 0.8361
Toxoplasma gondii thioredoxin reductase 0.0049 0.041 0.0726
Echinococcus granulosus cathepsin l1 0.0326 0.3718 0.4254
Onchocerca volvulus 0.0015 0.0008 0.0006
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.04 0.0458
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Schistosoma mansoni intermediate filament proteins 0.0029 0.0178 0.0204
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0702 0.0694
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0162 0.0186
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0077 0.0088
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.04 0.042
Loa Loa (eye worm) hypothetical protein 0.0326 0.3718 0.4214
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0028 0.0162 0.0186
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0102 0.1042 0.1193
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0021 0.0077 0.0131
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.3507 0.3975
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0518 0.0582
Echinococcus multilocularis musashi 0.0029 0.0178 0.0187
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0028 0.0162 0.0186
Loa Loa (eye worm) voltage-gated potassium channel 0.0024 0.0115 0.0126
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0031 0.0023
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.0115 0.0132
Leishmania major cysteine peptidase A (CPA) 0.0479 0.5542 0.5538
Schistosoma mansoni voltage-gated cation channel 0.0024 0.0115 0.0132
Brugia malayi calpain family protein 1 0.0058 0.0518 0.0582
Schistosoma mansoni zinc finger protein 0.0015 0.0013 0.0015
Schistosoma mansoni calpain (C02 family) 0.0022 0.009 0.0103
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0077 0.0082
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0075 0.0086
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.0115 0.0132
Echinococcus multilocularis snurportin 1 0.0308 0.3507 0.3685
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis tumor protein p63 0.0336 0.3833 0.4029
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Toxoplasma gondii exonuclease III APE 0.0056 0.0497 0.0883
Brugia malayi sulfakinin receptor protein 0.0021 0.0077 0.0082
Schistosoma mansoni hypothetical protein 0.0308 0.3507 0.4013
Brugia malayi Transient-receptor-potential like protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0326 0.3718 0.4214
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0702 0.0803
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0049 0.0051
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.0115 0.0121
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0024 0.0115 0.0126
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.04 0.0458
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0088
Loa Loa (eye worm) calcium channel 0.0024 0.0115 0.0126
Schistosoma mansoni myosin xvIII 0.0021 0.0077 0.0088
Schistosoma mansoni smad 0.0015 0.0005 0.0005
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0077 0.0081
Brugia malayi hypothetical protein 0.0024 0.0115 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.1042 0.1869
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0015 0.0017
Echinococcus granulosus hyperpolarization activated cyclic 0.0028 0.0162 0.0186
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0702 0.125
Echinococcus granulosus neuropeptide receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0077 0.0081
Schistosoma mansoni cathepsin F (C01 family) 0.0326 0.3718 0.4254
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0077 0.0082
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus multilocularis voltage dependent calcium channel 0.0024 0.0115 0.0121
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0024 0.0115 0.0121
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Toxoplasma gondii eukaryotic initiation factor-4A, putative 0.0025 0.0126 0.0213
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.1042 0.1193
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0088
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0381 0.0373
Entamoeba histolytica cysteine proteinase, putative 0.0255 0.2866 0.5165
Brugia malayi MH1 domain containing protein 0.0033 0.0221 0.0245
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0024 0.0115 0.0194
Schistosoma mansoni amine GPCR 0.0021 0.0077 0.0088
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0221 0.0252
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Echinococcus granulosus hyperpolarization activated cyclic 0.0028 0.0162 0.0186
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0077 0.0081
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0102 0.1042 0.1869
Leishmania major hypothetical protein, unknown function 0.0024 0.0115 0.0107
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0479 0.5542 0.6284
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0075 0.008
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0077 0.0088
Schistosoma mansoni neuropeptide receptor 0.0021 0.0077 0.0088
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Echinococcus granulosus neuropeptide receptor 0.0021 0.0077 0.0088
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0102 0.1042 0.1869
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0024 0.0115 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0075 0.008
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0381 0.0373
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0381 0.0436
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0031 0.0023
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Echinococcus granulosus cysteine protease 0.0255 0.2866 0.328
Toxoplasma gondii transporter, cation channel family protein 0.0024 0.0115 0.0194
Treponema pallidum ATP-dependent RNA helicase 0.0025 0.0126 0.0265
Brugia malayi Cytochrome P450 family protein 0.0016 0.002 0.0017
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.041 0.046
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) blistered cuticle protein 3 0.0064 0.0591 0.0665
Echinococcus multilocularis short transient receptor potential channel 6 0.0024 0.0115 0.0121
Loa Loa (eye worm) hypothetical protein 0.0211 0.2342 0.2653
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0015 0.0012
Plasmodium falciparum serine repeat antigen 8 0.0102 0.1042 0.1869
Loa Loa (eye worm) calpain 0.0022 0.009 0.0096
Toxoplasma gondii preprocathepsin c precursor, putative 0.0102 0.1042 0.1869
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0102 0.1042 0.1869
Schistosoma mansoni hypothetical protein 0.0082 0.0803 0.0919
Brugia malayi Melatonin receptor type 1A 0.0021 0.0077 0.0082
Loa Loa (eye worm) TATA binding protein associated factor 0.0015 0.0008 0.0004
Brugia malayi MH1 domain containing protein 0.0018 0.0046 0.0047
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0075 0.0086
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0028 0.0162 0.0179
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0075 0.008
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0024 0.0115 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0033
Echinococcus granulosus leukotriene A 4 hydrolase 0.0281 0.3177 0.3636
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0479 0.0548
Loa Loa (eye worm) aminopeptidase N 0.0015 0.0008 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.1042 0.1869
Brugia malayi Calcitonin receptor-like protein seb-1 0.0258 0.2905 0.3292
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0024 0.0115 0.0121
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0075 0.008
Echinococcus multilocularis cysteine protease 0.0479 0.5542 0.5824
Loa Loa (eye worm) CYP4Cod1 0.0016 0.002 0.0017
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0075 0.0079
Onchocerca volvulus 0.0049 0.0416 0.0743
Brugia malayi cathepsin L-like cysteine proteinase 0.0102 0.1042 0.1178
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0702 0.0791
Schistosoma mansoni cathepsin F (C01 family) 0.0479 0.5542 0.6342
Echinococcus granulosus cathepsin L 0.0255 0.2866 0.328
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0162 0.0186
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0077 0.0081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2052 0.2348
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Brugia malayi cathepsin L-like precursor 0.0326 0.3718 0.4214
Onchocerca volvulus 0.0021 0.0077 0.0131
Onchocerca volvulus Peroxidase homolog 0.0064 0.0591 0.1059
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0024 0.0115 0.0126
Plasmodium falciparum cysteine proteinase falcipain 3 0.0479 0.5542 1
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0077 0.0088
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0123 0.13 0.2364
Echinococcus multilocularis lamin dm0 0.0029 0.0178 0.0187
Brugia malayi mbt repeat family protein 0.0048 0.04 0.0449
Brugia malayi Peptidase family M1 containing protein 0.0015 0.0008 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0075 0.008
Loa Loa (eye worm) transcription factor SMAD2 0.048 0.5559 0.6305
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Plasmodium vivax serine-repeat antigen (SERA) 0.0102 0.1042 0.1869
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.0179
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0024 0.0115 0.0107
Trypanosoma cruzi hypothetical protein, conserved 0.0228 0.2545 0.2539
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0702 0.125
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Echinococcus granulosus eukaryotic initiation factor 4A III 0.0025 0.0126 0.0144
Echinococcus multilocularis muscleblind protein 1 0.0162 0.1759 0.1848
Plasmodium vivax vivapain-2 0.0479 0.5542 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0138 0.0158
Onchocerca volvulus 0.0048 0.04 0.0714
Brugia malayi calpain 7 0.0022 0.009 0.0096
Schistosoma mansoni hypothetical protein 0.0679 0.793 0.9076
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0702 0.0803
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0128 0.0216
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0028 0.0162 0.0179
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Plasmodium falciparum glutathione reductase 0.0017 0.0031 0.0042
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0042 0.0336 0.0377
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0111 0.1152 0.209
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0075 0.0086
Plasmodium falciparum serine repeat antigen 4 0.0102 0.1042 0.1869
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2052 0.2348
Onchocerca volvulus 0.0021 0.0077 0.0131
Brugia malayi calpain family protein 1 0.0058 0.0518 0.0582
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0007
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0803 0.0844
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0034 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0102 0.1042 0.1869
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0024 0.0115 0.0126
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0075 0.0079
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.0115 0.0132
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0136 0.0128
Plasmodium vivax importin-beta 2, putative 0.0029 0.0175 0.0301
Echinococcus multilocularis calpain A 0.006 0.0549 0.0577
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.0115 0.0132
Plasmodium falciparum glutathione reductase 0.0049 0.041 0.0726
Trypanosoma cruzi cysteine peptidase, putative 0.0153 0.1654 0.1648
Brugia malayi Cyclic-nucleotide gated cation channel 0.0028 0.0162 0.0179
Echinococcus granulosus aminopeptidase N 0.0015 0.0008 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0497 0.0489
Schistosoma mansoni ap endonuclease 0.0056 0.0497 0.0569
Giardia lamblia GTOR 0.0046 0.0381 0.098
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.2052 0.2323
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0127 0.0215
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0136 0.0232
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0038 0.0288 0.0322
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Plasmodium falciparum serine repeat antigen 2 0.0102 0.1042 0.1869
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0102 0.1042 0.1869
Echinococcus granulosus GPCR family 2 0.0082 0.0803 0.0919
Toxoplasma gondii hypothetical protein 0.0024 0.0115 0.0194
Brugia malayi fibroinase precursor 0.0102 0.1042 0.1178
Onchocerca volvulus 0.0021 0.0077 0.0131
Mycobacterium ulcerans proteasome PrcB 0.0069 0.0652 0.3867
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0126 0.0213
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Echinococcus granulosus importin subunit beta 1 0.0029 0.0175 0.02
Loa Loa (eye worm) hypothetical protein 0.0479 0.5542 0.6284
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0077 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0075 0.008
Echinococcus multilocularis gamma secretase subunit aph 1 0.0578 0.6725 0.7067
Schistosoma mansoni peroxidasin 0.0064 0.0591 0.0676
Echinococcus multilocularis serotonin receptor 0.0021 0.0077 0.0081
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0102 0.1042 0.1178
Treponema pallidum fructose-bisphosphate aldolase 0.0316 0.3603 1
Schistosoma mansoni opsin-like receptor 0.0021 0.0077 0.0088
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0028 0.0162 0.0179
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.0115 0.0132
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis calpain 5 0.0022 0.009 0.0094
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.2052 0.2348
Echinococcus granulosus microtubule associated protein 2 0.0747 0.8738 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0102 0.1042 0.1178
Loa Loa (eye worm) hypothetical protein 0.0049 0.0416 0.0467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0255 0.2866 0.2861
Schistosoma mansoni calpain-7 (C02 family) 0.0022 0.009 0.0103
Onchocerca volvulus 0.0021 0.0077 0.0131
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.7306 0.8361
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0024 0.0115 0.0126
Schistosoma mansoni ap endonuclease 0.0056 0.0497 0.0569
Echinococcus granulosus calpain A 0.0022 0.009 0.0103
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0024 0.0115 0.0121
Brugia malayi glutathione reductase 0.0049 0.041 0.046
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0162 0.0186
Schistosoma mansoni lamin 0.0029 0.0178 0.0204
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0024 0.0115 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0075 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.1042 0.1193
Echinococcus multilocularis potassium large conductance calcium activated 0.0024 0.0115 0.0121
Brugia malayi MH1 domain containing protein 0.0033 0.0221 0.0245
Trypanosoma cruzi cysteine peptidase, putative 0.0853 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0702 0.0694
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0574 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0075 0.008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Echinococcus granulosus cpg binding protein 0.0062 0.0575 0.0659
Echinococcus granulosus neuropeptide s receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis hypothetical protein 0.0022 0.009 0.0094
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0031 0.0138
Onchocerca volvulus Cathepsin L homolog 0.0479 0.5542 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0153 0.1654 0.1872
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0007
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0028 0.0162 0.0179
Leishmania major hypothetical protein, conserved 0.0073 0.0702 0.0694
Giardia lamblia Hypothetical protein 0.0102 0.1042 0.2831
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0178 0.0197
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0156 0.0268
Onchocerca volvulus 0.0064 0.0591 0.1059
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0031 0.0023
Leishmania major eukaryotic initiation factor 4a, putative 0.0025 0.0126 0.0118
Brugia malayi cation channel family protein 0.0024 0.0115 0.0126
Trypanosoma cruzi cysteine proteinase, putative 0.0255 0.2866 0.2861
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0803 0.0919
Brugia malayi G protein-coupled receptor 0.0021 0.0077 0.0082
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0702 0.1253
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0702 0.125
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0024 0.0115 0.0126
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Giardia lamblia Cathepsin B precursor 0.0102 0.1042 0.2831
Echinococcus granulosus two pore calcium channel protein 1 0.0024 0.0115 0.0132
Echinococcus multilocularis calpain 7 (C02 family) 0.0022 0.009 0.0094
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0111 0.1152 0.209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.1673 0.306
Echinococcus granulosus intermediate filament protein 0.0029 0.0178 0.0204
Echinococcus granulosus sodium leak channel non selective protein 0.0024 0.0115 0.0132
Loa Loa (eye worm) peptidase family M1 containing protein 0.0015 0.0008 0.0004
Giardia lamblia Encystation-specific protease 0.0102 0.1042 0.2831
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0021 0.008 0.0091
Loa Loa (eye worm) hypothetical protein 0.0258 0.2905 0.3292
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0013
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0077 0.0088
Toxoplasma gondii subtilisin SUB1 0.0173 0.1897 0.3414
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0082 0.0803 0.0906
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0102 0.1042 0.1869
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0013
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0077 0.0088
Echinococcus granulosus proteasome prosome macropain 0.0069 0.0652 0.0746
Entamoeba histolytica hypothetical protein 0.0023 0.0109 0.0183
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0102 0.1042 0.1869
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0582 0.0612
Brugia malayi Cytochrome P450 family protein 0.0016 0.002 0.0017
Onchocerca volvulus 0.0479 0.5542 1
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0024 0.0115 0.0107
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0497 0.0559
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0102 0.1042 0.1178
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0077 0.0081
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.1673 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0075 0.008
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0077 0.0081
Mycobacterium tuberculosis Conserved protein 0.0073 0.0702 0.125
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0281 0.3177 0.36
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.041 0.0402
Brugia malayi eukaryotic initiation factor 4A 0.0025 0.0126 0.0137
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0031 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0326 0.3718 0.6704
Onchocerca volvulus Peroxidasin homolog 0.0064 0.0591 0.1059
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1042 0.1869
Brugia malayi nuclear hormone receptor 0.0021 0.0075 0.008
Trypanosoma cruzi major cysteine proteinase, putative 0.0102 0.1042 0.1035
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0015 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0187 0.2057 0.3703
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0028 0.0162 0.0171
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0574 0.0567
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0077 0.0082
Echinococcus multilocularis Smad4 0.0033 0.0221 0.0232
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0136 0.0232
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0077 0.0081
Brugia malayi calpain 5 0.0015 0.0012 0.0008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0153 0.1654 0.1872
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0111 0.1152 0.209
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0497 0.0489
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0077 0.0088
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.04 0.0458
Giardia lamblia Translation initiation factor eIF-4A, putative 0.0025 0.0126 0.0265
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis hyperpolarization activated cyclic 0.0028 0.0162 0.0171
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0702 0.1253
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni smad1 5 8 and 0.0033 0.0221 0.0252
Onchocerca volvulus 0.0021 0.0077 0.0131
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0702 0.125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Echinococcus granulosus g protein coupled receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0221 0.0232
Mycobacterium tuberculosis Probable dehydrogenase 0.0111 0.1152 0.209
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0497 0.0569
Echinococcus granulosus lamin dm0 0.0029 0.0178 0.0204
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0162 0.0171
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0077 0.0088
Schistosoma mansoni hypothetical protein 0.0302 0.3428 0.3923
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0753 0.8815 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0162 0.0179
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) fibroinase 0.0479 0.5542 0.6284
Onchocerca volvulus Cathepsin F homolog 0.0479 0.5542 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0028 0.0162 0.0186
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.04 0.0458
Giardia lamblia Cathepsin L-like protease 0.0102 0.1042 0.2831
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.006 0.0549 0.0577
Entamoeba histolytica hypothetical protein 0.0036 0.0259 0.0454
Schistosoma mansoni calpain C (C02 family) 0.0022 0.009 0.0103
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0031 0.0042
Onchocerca volvulus 0.0021 0.0077 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.03 0.0529
Echinococcus multilocularis ryanodine receptor 44f 0.0024 0.0115 0.0121
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Toxoplasma gondii cathepsin CPL 0.0479 0.5542 1
Loa Loa (eye worm) cysteine protease 0.0479 0.5542 0.6284
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0017 0.0014
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Plasmodium falciparum serine repeat antigen 9 0.0102 0.1042 0.1869
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Schistosoma mansoni cathepsin C 0.0102 0.1042 0.1193
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.0115 0.0121
Echinococcus multilocularis serotonin receptor 0.0021 0.0077 0.0081
Echinococcus granulosus hypothetical protein 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0153 0.1654 0.1872
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0069 0.0652 0.0644
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0221 0.0252
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni neuropeptide receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) beta-lactamase 0.0073 0.0702 0.0791
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0031 0.003
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0077 0.0088
Mycobacterium tuberculosis Probable reductase 0.0111 0.1152 0.209
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni hypothetical protein 0.0024 0.0115 0.0132
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Echinococcus multilocularis muscleblind protein 0.0162 0.1759 0.1848
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0077 0.0088
Brugia malayi cation channel family protein 0.0024 0.0115 0.0126
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.9515 1
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0069 0.0652 0.1164
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0102 0.1042 0.1869
Giardia lamblia Cysteine protease 0.0102 0.1042 0.2831
Echinococcus granulosus zinc finger protein 0.0023 0.0103 0.0118
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.041 0.0469
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0077 0.0088
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0702 0.125
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Toxoplasma gondii proteasome subunit beta type, putative 0.0069 0.0652 0.1164
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.5542 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0034 0.0039
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0075 0.008
Entamoeba histolytica cysteine proteinase 2 0.0255 0.2866 0.5165
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0028 0.0162 0.0279
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0077 0.0081
Trypanosoma brucei calpain-like protein, putative 0.0022 0.009 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0069 0.0652 0.0644
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0075 0.008
Leishmania major cathepsin L-like protease 0.0853 1 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0497 0.0522
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0591 0.0665
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0075 0.0086
Onchocerca volvulus 0.0021 0.0077 0.0131
Loa Loa (eye worm) hypothetical protein 0.0162 0.1759 0.1991
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0028 0.0162 0.0171
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Entamoeba histolytica hypothetical protein 0.0036 0.0259 0.0454
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0004
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0075 0.008
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0175 0.0167
Echinococcus granulosus geminin 0.0679 0.793 0.9076
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Brugia malayi Importin beta-1 subunit 0.0029 0.0175 0.0193
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0029 0.0178 0.0197
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0077 0.0082
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0159 0.0273
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0049 0.0056
Brugia malayi G-protein coupled receptor 0.0021 0.0077 0.0082
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0077 0.0082
Onchocerca volvulus 0.0021 0.0077 0.0131
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0627 0.7306 0.8361
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0031 0.0023
Brugia malayi Cathepsin L-like precursor 0.0326 0.3718 0.4214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Schistosoma mansoni Smad4 0.0015 0.0005 0.0005
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0102 0.1042 0.1193
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0075 0.0086
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0004
Trichomonas vaginalis esterase, putative 0.0073 0.0702 0.1253
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Trypanosoma brucei antigen, putative 0.0022 0.009 0.0082
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0136 0.0232
Plasmodium falciparum serine repeat antigen 5 0.0102 0.1042 0.1869
Echinococcus multilocularis cysteine protease 0.0479 0.5542 0.5824
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0017
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0015 0.0008 0.0008
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0028 0.0162 0.0186
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0028 0.0162 0.0179
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0075 0.0127
Schistosoma mansoni hypothetical protein 0.0036 0.0259 0.0296
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Onchocerca volvulus 0.0479 0.5542 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0128 0.0216
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0479 0.0548
Echinococcus granulosus muscleblind protein 0.0162 0.1759 0.2012
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0077 0.0082
Brugia malayi MH2 domain containing protein 0.048 0.5559 0.6305
Mycobacterium tuberculosis Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) 0.0025 0.0126 0.0176
Echinococcus multilocularis somatostatin receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0479 0.5542 0.6284
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0102 0.1042 0.1869
Schistosoma mansoni cathepsin F (C01 family) 0.0479 0.5542 0.6342
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Echinococcus multilocularis cathepsin L cysteine protease 0.0479 0.5542 0.5824
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0075 0.008
Giardia lamblia Cysteine protease 0.0102 0.1042 0.2831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.2866 0.5165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0077 0.0081
Schistosoma mansoni neuropeptide receptor 0.0021 0.0077 0.0088
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0497 0.0883
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.0115 0.0132
Echinococcus granulosus smad 0.0033 0.0221 0.0252
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0024 0.0115 0.0121
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0182 0.2007 0.3615
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Entamoeba histolytica hypothetical protein 0.0102 0.1042 0.1869
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0024 0.0115 0.0121
Schistosoma mansoni opsin-like receptor 0.0021 0.0077 0.0088
Trypanosoma cruzi cruzipain precursor, putative 0.0153 0.1654 0.1648
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0702 0.1253
Schistosoma mansoni Smad4 0.0015 0.0005 0.0005
Onchocerca volvulus 0.0479 0.5542 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Brugia malayi Peptidase family M1 containing protein 0.0015 0.0008 0.0004
Onchocerca volvulus 0.0479 0.5542 1
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0381 0.0373
Brugia malayi Papain family cysteine protease containing protein 0.0255 0.2866 0.3248
Plasmodium falciparum thioredoxin reductase 0.0049 0.041 0.0726
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0075 0.0079
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0031 0.0042
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0115 0.0132
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0077 0.0088
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0264 0.2979 0.341
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Brugia malayi cathepsin Z-like cysteine proteinase 0.0102 0.1042 0.1178
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.041 0.0431
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0024 0.0115 0.0132
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Echinococcus multilocularis proteasome (prosome, macropain) 0.0069 0.0652 0.0685
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0381 0.0427
Brugia malayi RE15519p 0.0021 0.0077 0.0082
Echinococcus multilocularis GPCR, family 2 0.0082 0.0803 0.0844
Echinococcus multilocularis cathepsin L cysteine protease 0.0479 0.5542 0.5824
Entamoeba histolytica DEAD/DEAH box helicase, putative 0.0025 0.0126 0.0213
Brugia malayi beta-lactamase 0.0073 0.0702 0.0791
Brugia malayi MH1 domain containing protein 0.0018 0.0046 0.0047
Schistosoma mansoni adenoreceptor 0.0021 0.0077 0.0088
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0024 0.0115 0.02
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0015 0.0007
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0077 0.0088
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.0115 0.0121
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0591 0.0665
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0077 0.0081
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0077 0.0081
Echinococcus granulosus cathepsin L cysteine proteinase 0.0479 0.5542 0.6342
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.1042 0.1178
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0077 0.0088
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0497 0.1304
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0479 0.5542 1
Giardia lamblia Cathepsin B precursor 0.0102 0.1042 0.2831
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.0115 0.0121
Entamoeba histolytica hypothetical protein 0.0228 0.2545 0.4584
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0028 0.0162 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.1042 0.1869
Schistosoma mansoni bromodomain containing protein 0.0067 0.0625 0.0715
Plasmodium falciparum proteasome subunit beta type-5 0.0069 0.0652 0.1164
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0049 0.0056
Mycobacterium ulcerans beta-lactamase 0.0073 0.0702 0.4165
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0102 0.1042 0.1869
Plasmodium falciparum subtilisin-like protease 1 0.0173 0.1897 0.3414
Leishmania major hypothetical protein, conserved 0.0026 0.0136 0.0128
Loa Loa (eye worm) hypothetical protein 0.0182 0.2007 0.2272
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Onchocerca volvulus 0.0073 0.0702 0.1259
Brugia malayi Cathepsin L-like precursor 0.0153 0.1654 0.1872
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0102 0.1042 0.2831
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Trypanosoma brucei ISWI complex protein 0.0015 0.0013 0.0005
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0077 0.0088
Brugia malayi AKH receptor 0.0021 0.0077 0.0082
Echinococcus granulosus two pore calcium channel protein 2 0.0024 0.0115 0.0132
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0123 0.13 0.2364
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Onchocerca volvulus Dual oxidase homolog 0.0064 0.0591 0.1059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0514 0.0578
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0007
Brugia malayi RNA, U transporter 1 0.0082 0.081 0.0914
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0803 0.0906
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.128 0.1465
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0702 0.1253
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0077 0.0088
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0381 0.0373
Schistosoma mansoni microtubule-associated protein tau 0.0747 0.8738 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.2052 0.2156
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0075 0.0079
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0031 0.0138
Onchocerca volvulus 0.0015 0.0008 0.0006
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0077 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.02 0.0346
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0175 0.0301
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0031 0.0042
Schistosoma mansoni neuropeptide receptor 0.0021 0.0077 0.0088
Echinococcus granulosus allatostatin A receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0077 0.0081
Echinococcus granulosus TRP transient receptor potential channel 0.0024 0.0115 0.0132
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0077 0.0082
Toxoplasma gondii ABC1 family protein 0.0073 0.0702 0.1253
Brugia malayi hypothetical protein 0.0026 0.0136 0.0149
Echinococcus multilocularis two pore calcium channel protein 2 0.0024 0.0115 0.0121
Loa Loa (eye worm) hypothetical protein 0.0051 0.044 0.0494
Schistosoma mansoni two-pore calcium channel 0.0024 0.0115 0.0132
Giardia lamblia Cathepsin L-like protease 0.0102 0.1042 0.2831
Giardia lamblia Cathepsin B precursor 0.0102 0.1042 0.2831
Entamoeba histolytica cysteine protease, putative 0.0479 0.5542 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0058 0.0518 0.0593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0128 0.0216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0024 0.0115 0.0132
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0075 0.0086
Schistosoma mansoni smad1 5 8 and 0.0033 0.0221 0.0252
Loa Loa (eye worm) hypothetical protein 0.0326 0.3718 0.4214
Plasmodium falciparum cysteine proteinase falcipain 1 0.0255 0.2866 0.5165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0582 0.0666
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0028 0.0162 0.0186
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0077 0.0081
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0024 0.0115 0.0132
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0031 0.5
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.2052 0.2348
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0088
Plasmodium vivax unspecified product 0.0153 0.1654 0.2975
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0702 0.0803
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0059 0.0051
Schistosoma mansoni Mername-AA248 (C02 family) 0.0022 0.009 0.0103
Mycobacterium ulcerans lipase LipD 0.0073 0.0702 0.4165
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0221 0.0245
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0102 0.1042 0.1869
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.04 0.0458
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0015 0.0008 0.0008
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Brugia malayi G-protein coupled receptor 0.0021 0.0077 0.0082
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0031 0.0042
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0091 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0255 0.2866 0.5165
Echinococcus multilocularis sodium channel protein 0.0024 0.0115 0.0121
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0159 0.0273
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0574 0.3402
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0111 0.1152 0.209
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0102 0.1042 0.1869
Loa Loa (eye worm) hypothetical protein 0.0153 0.1654 0.1872
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0497 0.0489
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Entamoeba histolytica cysteine proteinase, putative 0.0255 0.2866 0.5165
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Echinococcus multilocularis neuropeptide receptor A26 0.0021 0.0077 0.0081
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0069 0.0652 0.0644
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0497 0.0883
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.002 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0077 0.0088
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0024 0.0115 0.0126
Plasmodium falciparum eukaryotic initiation factor 4A 0.0025 0.0126 0.0213
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.0077 0.0082
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0077 0.0082
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0028 0.0162 0.0186
Brugia malayi Blistered cuticle protein 3 0.0064 0.0591 0.0665
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Toxoplasma gondii cathepsin CPC1 0.0102 0.1042 0.1869
Echinococcus granulosus voltage gated potassium channel 0.0028 0.0162 0.0186
Echinococcus multilocularis dnaJ subfamily B 0.0416 0.4796 0.5041
Brugia malayi beta-lactamase family protein 0.0073 0.0702 0.0791
Mycobacterium tuberculosis Probable oxidoreductase 0.0123 0.13 0.2364
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0221 0.0252
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0102 0.1042 0.1178
Schistosoma mansoni amine GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0077 0.0088
Leishmania major kinesin, putative 0.0015 0.0012 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0172 0.019
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0479 0.5542 0.5824
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.1153 0.207
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0024 0.0115 0.0121
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0702 0.1253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0077 0.0088
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0075 0.0127
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0024 0.0115 0.0132
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0803 0.0906
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Loa Loa (eye worm) voltage-gated calcium channel 0.0024 0.0115 0.0126
Brugia malayi ORL1-like opioid receptor 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0075 0.0079
Loa Loa (eye worm) voltage-dependent calcium channel 0.0024 0.0115 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0381 0.0674
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0259 0.0296
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0702 0.125
Echinococcus granulosus voltage gated potassium channel 0.0024 0.0115 0.0132
Toxoplasma gondii hypothetical protein 0.0024 0.0115 0.0194
Brugia malayi hypothetical protein 0.0015 0.0008 0.0004
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0574 0.0657
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0031 0.0023
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0138
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0077 0.0088
Brugia malayi Cathepsin L-like precursor 0.0479 0.5542 0.6284
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0803 0.0919
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0015 0.0016
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Onchocerca volvulus 0.0021 0.0077 0.0131
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0281 0.3177 0.3339
Onchocerca volvulus 0.0021 0.0077 0.0131
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus multilocularis two pore calcium channel protein 1 0.0024 0.0115 0.0121
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0075 0.008
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0591 0.0665
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0024 0.0115 0.0132
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0042 0.0048
Echinococcus granulosus voltage dependent calcium channel 0.0024 0.0115 0.0132
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0627 0.7306 0.8361
Trypanosoma cruzi Aph-1 protein, putative 0.0225 0.2517 0.2511
Schistosoma mansoni amine GPCR 0.0021 0.0077 0.0088
Brugia malayi Bromodomain containing protein 0.0038 0.0288 0.0321
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0077 0.0088
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0034 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0049 0.0056
Plasmodium vivax subtilisin-like protease 1 0.0173 0.1897 0.3414
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.1673 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis smad 0.0033 0.0221 0.0232
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0077 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0127 0.0215
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Echinococcus granulosus serotonin receptor 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0077 0.0088
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0077 0.0088
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0211 0.2342 0.2653
Brugia malayi hypothetical protein 0.0129 0.1369 0.1548
Echinococcus granulosus cathepsin l cysteine peptidase 0.0479 0.5542 0.6342
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0075 0.008
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0102 0.1042 0.1869
Brugia malayi CXXC zinc finger family protein 0.0057 0.0514 0.0578
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0022 0.009 0.0082
Plasmodium vivax unspecified product 0.0102 0.1042 0.1869
Brugia malayi hypothetical protein 0.0064 0.0591 0.0665
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Echinococcus granulosus short transient receptor potential channel 6 0.0024 0.0115 0.0132
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Schistosoma mansoni hypothetical protein 0.0416 0.4796 0.5489
Echinococcus granulosus shaker cognate 0.0024 0.0115 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0381 0.0674
Plasmodium falciparum thioredoxin reductase 0.0017 0.0031 0.0042
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0024 0.0115 0.0132
Mycobacterium tuberculosis Conserved protein 0.0073 0.0702 0.125
Brugia malayi Cathepsin L-like precursor 0.0326 0.3718 0.4214
Brugia malayi Proteasome A-type and B-type family protein 0.0069 0.0652 0.0735
Schistosoma mansoni amine GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni hypothetical protein 0.0082 0.0803 0.0919
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0077 0.0088
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0031 0.0042
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0017 0.0014
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0028 0.0162 0.0171
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus granulosus cathepsin L 0.0102 0.1042 0.1193
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0102 0.1042 0.1869
Onchocerca volvulus 0.0029 0.0178 0.0314
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0109 0.0102
Brugia malayi gamma-secretase subunit aph-1 0.0578 0.6725 0.7627
Echinococcus multilocularis cpg binding protein 0.0062 0.0575 0.0605
Brugia malayi ion channel NompC 0.0024 0.0115 0.0126
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0077 0.0082
Schistosoma mansoni gamma-secretase subunit aph-1 0.0578 0.6725 0.7696
Trypanosoma cruzi cysteine proteinase, putative 0.0255 0.2866 0.2861
Entamoeba histolytica calpain large subunit domain III containing protein 0.0015 0.0012 0.0007
Trypanosoma brucei Aph-1 protein, putative 0.0225 0.2517 0.2511
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Brugia malayi cathepsin F-like cysteine proteinase 0.0102 0.1042 0.1178
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0041 0.0041
Schistosoma mansoni voltage-gated ion channel 0.0024 0.0115 0.0132
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0075 0.0079
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Trypanosoma cruzi cruzipain precursor, putative 0.0853 1 1
Entamoeba histolytica cysteine proteinase 1, putative 0.0255 0.2866 0.5165
Onchocerca volvulus 0.0021 0.0077 0.0131
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0255 0.2866 0.328
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0126 0.0144
Plasmodium vivax calpain, putative 0.0022 0.009 0.0147
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus short transient receptor potential channel 6 0.0024 0.0115 0.0132
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Echinococcus multilocularis calpain family protein 1, d 0.0042 0.0336 0.0354
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0042 0.0044
Brugia malayi hypothetical protein 0.0015 0.0008 0.0004
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0077 0.0088
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0031 0.0042
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.07 0.8176 0.8174
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0077 0.0082
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0005 0.0005
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Trypanosoma brucei cysteine peptidase C (CPC) 0.0264 0.2979 0.2974
Brugia malayi neuropeptide F receptor 0.0021 0.0077 0.0082
Giardia lamblia Cysteine protease 0.0102 0.1042 0.2831
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0077 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0075 0.008
Loa Loa (eye worm) hypothetical protein 0.0073 0.0702 0.0791
Loa Loa (eye worm) animal heme peroxidase 0.0064 0.0591 0.0665
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0803 0.0844
Brugia malayi Smad1 0.0033 0.0221 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0803 0.0906
Echinococcus multilocularis lamin 0.0029 0.0178 0.0187
Brugia malayi hypothetical protein 0.0036 0.0259 0.0289
Echinococcus multilocularis short transient receptor potential channel 6 0.0024 0.0115 0.0121
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.002 0.0017
Leishmania major importin beta-1 subunit, putative 0.0023 0.0109 0.0102
Schistosoma mansoni cpg binding protein 0.0057 0.0514 0.0588
Loa Loa (eye worm) hypothetical protein 0.0627 0.7306 0.8287
Plasmodium vivax vivapain-2 0.0479 0.5542 1
Schistosoma mansoni peroxidasin 0.0064 0.0591 0.0676
Onchocerca volvulus 0.0479 0.5542 1
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0126 0.0213
Echinococcus granulosus calpain 5 0.0022 0.009 0.0103
Loa Loa (eye worm) hypothetical protein 0.0026 0.0136 0.0149
Echinococcus multilocularis eukaryotic initiation factor 4A III 0.0025 0.0126 0.0132
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0077 0.0082
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0479 0.0548
Echinococcus granulosus neuropeptide receptor A26 0.0021 0.0077 0.0088
Giardia lamblia Fructose-bisphosphate aldolase 0.0316 0.3603 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0023
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0702 0.1253
Echinococcus multilocularis transient receptor potential gamma protein 0.0024 0.0115 0.0121
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Brugia malayi Angiotensin-converting enzyme family protein 0.0753 0.8815 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0028 0.0162 0.0186
Brugia malayi Serotonin receptor 0.0021 0.0077 0.0082
Trypanosoma cruzi Eukaryotic initiation factor 4A-1 0.0025 0.0126 0.0118
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0024 0.0115 0.0121
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0024 0.0115 0.0132
Brugia malayi follicle stimulating hormone receptor 0.0021 0.0077 0.0082
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0102 0.1042 0.1869
Brugia malayi ecdysteroid receptor 0.0021 0.0075 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0075 0.008
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0264 0.2979 0.2974
Brugia malayi Animal haem peroxidase family protein 0.0064 0.0591 0.0665
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0022 0.009 0.0082
Loa Loa (eye worm) hypothetical protein 0.0054 0.0479 0.0538
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0077 0.0088
Schistosoma mansoni cpg binding protein 0.0062 0.0575 0.0659
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0075 0.0086
Schistosoma mansoni 60S ribosomal protein L21 0.0024 0.0115 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0013
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0024 0.0115 0.0132
Loa Loa (eye worm) calpain family protein 1 0.0042 0.0336 0.0377
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0138 0.0158
Schistosoma mansoni transient receptor potential channel 0.0024 0.0115 0.0132
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0031 0.0023
Echinococcus granulosus endonuclease exonuclease phosphatase 0.02 0.221 0.2529
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0077 0.0081
Echinococcus granulosus potassium voltage gated channel protein 0.0024 0.0115 0.0132
Onchocerca volvulus 0.0036 0.0258 0.0458
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0123 0.13 0.6344
Trypanosoma cruzi kinesin, putative 0.0015 0.0012 0.0004
Echinococcus granulosus fmrfamide receptor 0.0021 0.0077 0.0088
Trypanosoma cruzi cysteine protease, putative 0.0255 0.2866 0.2861
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.041 0.0706
Brugia malayi putative neuropeptide receptor 0.0021 0.0077 0.0082
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0381 0.0427
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0115 0.0126
Echinococcus granulosus gamma secretase subunit aph 1 0.0578 0.6725 0.7696
Echinococcus multilocularis microtubule associated protein 2 0.0747 0.8738 0.9184
Onchocerca volvulus 0.0015 0.0008 0.0006
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Trypanosoma cruzi ISWI complex protein 0.0015 0.0013 0.0005
Entamoeba histolytica hypothetical protein 0.0036 0.0259 0.0454
Loa Loa (eye worm) calpain 5 0.0015 0.0012 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Schistosoma mansoni voltage-gated potassium channel 0.0024 0.0115 0.0132
Echinococcus multilocularis neuropeptide s receptor 0.0021 0.0077 0.0081
Brugia malayi cathepsin L precursor 0.0102 0.1042 0.1178
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0075 0.008
Schistosoma mansoni histamine h1 receptor 0.0021 0.0077 0.0088
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0102 0.1042 0.1869
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0077 0.0081
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.1042 0.1178
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.2052 0.2156
Echinococcus multilocularis aminopeptidase N 0.0015 0.0008 0.0008
Schistosoma mansoni biogenic amine receptor 0.0021 0.0077 0.0088
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0075 0.0086
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0069 0.0652 0.1738
Brugia malayi N-terminal motif family protein 0.0182 0.2007 0.2272
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0015 0.0008 0.0009
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0077 0.0081
Schistosoma mansoni cathepsin B (C01 family) 0.0102 0.1042 0.1193
Brugia malayi neuropeptide F receptor 0.0021 0.0077 0.0082
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0075 0.008
Loa Loa (eye worm) Smad1 0.0033 0.0221 0.0245
Toxoplasma gondii cathepsin CPC2 0.0102 0.1042 0.1869
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.024 0.0419
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0015 0.0008 0.0009
Echinococcus multilocularis cathepsin L 0.0255 0.2866 0.3012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.024 0.0419
Trypanosoma cruzi cysteine peptidase, putative 0.0479 0.5542 0.5538
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0259 0.0272
Plasmodium falciparum serine repeat antigen 6 0.0102 0.1042 0.1869
Echinococcus granulosus potassium large conductance calcium activated 0.0024 0.0115 0.0132
Schistosoma mansoni transient receptor potential channel 0.0024 0.0115 0.0132
Plasmodium falciparum serine repeat antigen 3 0.0102 0.1042 0.1869
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0077 0.0081
Leishmania major cathepsin L-like protease 0.0479 0.5542 0.5538
Trypanosoma cruzi ISWI complex protein 0.0015 0.0013 0.0005
Brugia malayi olfactory channel protein osm-9 0.0024 0.0115 0.0126
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0497 0.0489
Loa Loa (eye worm) hypothetical protein 0.0153 0.1654 0.1872
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis cathepsin b 0.0627 0.7306 0.7678
Leishmania major proteasome beta 5 subunit, putative 0.0069 0.0652 0.0644
Plasmodium vivax serine-repeat antigen (SERA) 0.0102 0.1042 0.1869
Entamoeba histolytica cysteine protease, putative 0.0102 0.1042 0.1869
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0024 0.0115 0.0132
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0497 0.0883
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0024 0.0115 0.0107
Plasmodium vivax glutathione reductase, putative 0.0049 0.041 0.0726
Brugia malayi Papain family cysteine protease containing protein 0.0102 0.1042 0.1178
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0115 0.0121
Schistosoma mansoni transient receptor potential channel 0.0024 0.0115 0.0132
Onchocerca volvulus 0.0021 0.0077 0.0131
Schistosoma mansoni hypothetical protein 0.0679 0.793 0.9076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) calpain family protein 1 0.0058 0.0518 0.0582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0128 0.0216
Brugia malayi Dopamine receptor protein 1 0.0021 0.0077 0.0082
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0024 0.0115 0.0132
Onchocerca volvulus 0.0073 0.0702 0.1259
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0077 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0255 0.2866 0.2861
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0574 0.0604
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0268 0.047
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.1042 0.1193
Brugia malayi mbt repeat family protein 0.0048 0.04 0.0449
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Onchocerca volvulus 0.0064 0.0591 0.1059
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.02 0.221 0.2322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0159 0.0273
Echinococcus granulosus eukaryotic initiation factor 4A 0.0025 0.0126 0.0144
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni aminopeptidase A (M01 family) 0.0015 0.0008 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0188 0.0325
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0381 0.0674
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0024 0.0115 0.0126
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0024 0.0115 0.0121
Giardia lamblia Cysteine protease 0.0102 0.1042 0.2831
Onchocerca volvulus 0.0479 0.5542 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0102 0.1042 0.1193
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0024 0.0115 0.0194
Entamoeba histolytica cysteine protease, putative 0.0255 0.2866 0.5165
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0015 0.0008 0.0009
Echinococcus granulosus calpain A 0.006 0.0549 0.0628
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0075 0.0086
Schistosoma mansoni smad1 5 8 and 0.0033 0.0221 0.0252
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0153 0.1654 0.1872
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0258 0.2905 0.3292
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0479 0.5542 1
Loa Loa (eye worm) glutathione reductase 0.0049 0.041 0.046
Leishmania major hypothetical protein, conserved 0.0015 0.0013 0.0005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Trypanosoma brucei trypanothione reductase 0.0049 0.041 0.0402
Echinococcus granulosus g protein coupled receptor 0.0021 0.0077 0.0088
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0479 0.0503
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0162 0.1759 0.1991
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0259 0.0296
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0381 0.0436
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0077 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0102 0.1042 0.1869
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0028 0.0162 0.0186
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Echinococcus multilocularis voltage gated potassium channel 0.0028 0.0162 0.0171
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0268 0.047
Plasmodium vivax RNA helicase-1, putative 0.0025 0.0126 0.0213
Leishmania major cytochrome p450-like protein 0.0016 0.002 0.0012
Echinococcus granulosus g protein coupled receptor 0.0021 0.0077 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0381 0.0674
Loa Loa (eye worm) hypothetical protein 0.0025 0.0126 0.0137
Echinococcus multilocularis potassium voltage gated channel protein 0.0024 0.0115 0.0121
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0075 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0075 0.008
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0497 0.1304
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0075 0.008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0015 0.0013
Schistosoma mansoni voltage-gated potassium channel 0.0028 0.0162 0.0186
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0024 0.0115 0.0126
Schistosoma mansoni ryanodine receptor related 0.0024 0.0115 0.0132
Brugia malayi MH2 domain containing protein 0.0033 0.0221 0.0245
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0077 0.0082
Leishmania major cathepsin L-like protease 0.0479 0.5542 0.5538
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0077 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0028 0.0162 0.0186
Loa Loa (eye worm) MBCTL1 0.0054 0.0479 0.0538
Brugia malayi voltage-dependent calcium channel 0.0024 0.0115 0.0126
Schistosoma mansoni hypothetical protein 0.0021 0.0077 0.0088
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0102 0.1042 0.1193
Entamoeba histolytica cysteine proteinase, putative 0.0255 0.2866 0.5165
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0077 0.0082
Echinococcus granulosus transient receptor potential cation channel 0.0024 0.0115 0.0132
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni hypothetical protein 0.0176 0.1932 0.2211
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0023
Entamoeba histolytica cysteine proteinase, putative 0.0479 0.5542 1
Onchocerca volvulus 0.0024 0.0115 0.02
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0702 0.4165
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0702 0.125
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0069 0.0652 0.0735
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0574 0.1013
Entamoeba histolytica hypothetical protein 0.0036 0.0259 0.0454
Onchocerca volvulus 0.0021 0.0077 0.0131
Loa Loa (eye worm) hypothetical protein 0.0102 0.1042 0.1178
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0156 0.0268
Mycobacterium tuberculosis Conserved protein 0.0073 0.0702 0.125
Onchocerca volvulus 0.0102 0.1042 0.1874
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0024 0.0115 0.0132
Echinococcus granulosus voltage gated hydrogen channel 1 0.0024 0.0115 0.0132
Schistosoma mansoni opsin-like receptor 0.0021 0.0077 0.0088
Schistosoma mansoni amine GPCR 0.0021 0.0077 0.0088
Loa Loa (eye worm) hypothetical protein 0.0064 0.0591 0.0665
Brugia malayi latrophilin 2 splice variant baaae 0.0176 0.1932 0.2188
Schistosoma mansoni transient receptor potential channel 4 0.0024 0.0115 0.0132
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0024 0.0115 0.0126
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0077 0.0081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0075 0.0086
Onchocerca volvulus Cathepsin L homolog 0.0479 0.5542 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0479 0.5542 0.5824
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0258 0.2905 0.3292
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0259 0.0297
Plasmodium vivax proteasome subunit beta type-5, putative 0.0069 0.0652 0.1164
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0077 0.0082
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0028 0.0162 0.0171
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0578 0.6725 0.7627
Echinococcus multilocularis peroxidasin 0.0064 0.0591 0.0621
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0702 0.4165
Echinococcus granulosus lamin 0.0029 0.0178 0.0204
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0497 0.0883
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0175 0.0167
Onchocerca volvulus 0.0064 0.0591 0.1059
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0467 0.5397 1
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0024 0.0115 0.0132
Trypanosoma cruzi hypothetical protein, conserved 0.0228 0.2545 0.2539
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0077 0.0081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 1 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0077 0.0088
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0075 0.0086
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0102 0.1042 0.1869
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0381 0.04
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2052 0.2348
Loa Loa (eye worm) MH2 domain-containing protein 0.048 0.5559 0.6305
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0269 0.0261
Loa Loa (eye worm) hypothetical protein 0.0071 0.0675 0.0761
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0069 0.0652 0.1157
Brugia malayi hypothetical protein 0.0021 0.0077 0.0082
Schistosoma mansoni DEAD box ATP-dependent RNA helicase 0.0025 0.0126 0.0144
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0077 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0479 0.5542 1
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0574 0.1024
Echinococcus multilocularis voltage gated potassium channel 0.0024 0.0115 0.0121
Schistosoma mansoni cathepsin S (C01 family) 0.0102 0.1042 0.1193
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0015 0.0007
Giardia lamblia Cathepsin L precursor 0.0102 0.1042 0.2831
Brugia malayi nuclear receptor NHR-88 0.0021 0.0075 0.008
Schistosoma mansoni coup transcription factor 0.0021 0.0075 0.0086
Echinococcus granulosus orexin receptor type 2 0.0021 0.0077 0.0088
Trichomonas vaginalis DEAD box ATP-dependent RNA helicase, putative 0.0025 0.0126 0.0213
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0175 0.0183
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0077 0.0088
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0077 0.0081
Trypanosoma cruzi cysteine peptidase, putative 0.0853 1 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0255 0.2866 0.328
Echinococcus granulosus peroxidasin 0.0064 0.0591 0.0676
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0024 0.0115 0.0107
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3603 0.6497
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0497 0.0883
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0022 0.009 0.0082

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 2.7 uM Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation. ChEMBL. 9873407
IC50 (binding) = 2.7 uM Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to a thrombin receptor (PAR-1) membrane preparation. ChEMBL. 9873407
IC50 (functional) = 4.6 uM Inhibition of TRAP-6 (SFLLRN-NH2)-induced human gel filtered platelet aggregation (GFP). ChEMBL. 9873407
IC50 (functional) = 4.6 uM Inhibition of TRAP-6 (SFLLRN-NH2)-induced human gel filtered platelet aggregation (GFP). ChEMBL. 9873407
IC50 (functional) = 22 uM Inhibition of alpha-thrombin-induced human gel filtered platelet aggregation (GFP). ChEMBL. 9873407
IC50 (functional) = 22 uM Inhibition of alpha-thrombin-induced human gel filtered platelet aggregation (GFP). ChEMBL. 9873407

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9873407

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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