Detailed information for compound 659958

Basic information

Technical information
  • TDR Targets ID: 659958
  • Name: 3-amino-5-(4-fluorophenyl)-6-methylthieno[3,2 -e]pyrimidin-4-one
  • MW: 275.301 | Formula: C13H10FN3OS
  • H donors: 1 H acceptors: 1 LogP: 2.28 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)c1c(C)sc2c1c(=O)n(cn2)N
  • InChi: 1S/C13H10FN3OS/c1-7-10(8-2-4-9(14)5-3-8)11-12(19-7)16-6-17(15)13(11)18/h2-6H,15H2,1H3
  • InChiKey: HPGVLAYJVYTJED-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-amino-5-(4-fluorophenyl)-6-methyl-thieno[3,2-e]pyrimidin-4-one
  • 3-amino-5-(4-fluorophenyl)-6-methyl-4-thieno[3,2-e]pyrimidinone
  • T0513-5197
  • ZINC04284313

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei Heat shock protein 83, putative 0.0027 0.0124 0.0114
Trichomonas vaginalis rotamase, putative 0.0021 0.0071 0.0117
Schistosoma mansoni cpg binding protein 0.0057 0.04 0.0534
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0027 0.0122 0.0122
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0015 0.0015
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0027 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.013 0.1076 0.1121
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0023 0.009 0.0136
Leishmania major prostaglandin f synthase, putative 0.0028 0.013 0.0121
Echinococcus granulosus sodium and chloride dependent glycine 0.0014 0.0008 0.0008
Echinococcus granulosus GPCR family 2 0.0049 0.0327 0.0327
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis lamin dm0 0.0051 0.0343 0.0343
Schistosoma mansoni hypothetical protein 0.0146 0.122 0.1651
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0023 0.009 0.0136
Echinococcus multilocularis geminin 0.0287 0.252 0.252
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0069 0.0509 0.0509
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0023 0.009 0.0136
Mycobacterium leprae Probable penicillin-binding protein PbpA 0.0128 0.1056 0.6441
Loa Loa (eye worm) CYP4Cod1 0.0023 0.009 0.0095
Trypanosoma brucei prostaglandin f synthase 0.0028 0.013 0.0121
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0122 0.0122
Trypanosoma cruzi heat shock protein 85, putative 0.0021 0.0073 0.0061
Schistosoma mansoni aryl hydrocarbon receptor 0.0046 0.03 0.0398
Echinococcus multilocularis endoplasmin 0.0021 0.0073 0.0073
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0119 0.0975 0.1015
Echinococcus granulosus heat shock protein 0.0027 0.0124 0.0124
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Onchocerca volvulus 0.0117 0.0954 0.2052
Brugia malayi Bromodomain containing protein 0.0078 0.0594 0.0625
Brugia malayi hypothetical protein 0.0019 0.0047 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0122 0.0122
Schistosoma mansoni pol-related 0.0028 0.013 0.0167
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0122 0.0122
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0163 0.0316
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Toxoplasma gondii histone lysine-specific demethylase 0.0021 0.0072 0.0668
Mycobacterium ulcerans penicillin-binding lipoprotein 0.0189 0.1619 0.4085
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0122 0.0122
Echinococcus granulosus biogenic amine 5HT receptor 0.0027 0.0122 0.0122
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Echinococcus multilocularis RUN 0.0019 0.0047 0.0047
Echinococcus multilocularis serotonin receptor 0.0027 0.0122 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Loa Loa (eye worm) oxidoreductase 0.0028 0.013 0.0138
Trypanosoma cruzi Heat shock protein 83, putative 0.0027 0.0124 0.0114
Loa Loa (eye worm) hypothetical protein 0.0024 0.0101 0.0106
Toxoplasma gondii thioredoxin reductase 0.003 0.015 0.147
Echinococcus granulosus neuropeptide receptor 0.0027 0.0122 0.0122
Echinococcus granulosus lysine specific histone demethylase 1A 0.0018 0.0037 0.0037
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0023 0.009 0.0136
Trypanosoma brucei aldo-keto reductase, putative 0.0028 0.013 0.0121
Brugia malayi G protein-coupled receptor 0.0027 0.0122 0.0127
Loa Loa (eye worm) hypothetical protein 0.0414 0.3689 0.3893
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0057 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0163 0.0155
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0023 0.009 0.0136
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.013 0.1076 0.1121
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0068 0.0502 0.12
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0047 0.0311 0.0311
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0015 0.0011
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0031 0.0163 0.1602
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0765 0.0765
Loa Loa (eye worm) hypothetical protein 0.0032 0.0174 0.0184
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0023 0.009 0.0136
Brugia malayi hypothetical protein 0.0155 0.13 0.137
Trypanosoma cruzi aldo-keto reductase 0.0028 0.013 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0316 0.0721
Loa Loa (eye worm) phosphofructokinase 0.011 0.0889 0.0939
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0327 0.0327
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.1305 0.1377
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Echinococcus granulosus Squalene phytoene synthase 0.0146 0.122 0.122
Trypanosoma cruzi heat shock protein 90, putative 0.0021 0.0073 0.0061
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0023 0.009 0.0136
Onchocerca volvulus 0.013 0.1076 0.2318
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0316 0.0648
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0023 0.009 0.0136
Leishmania major aldo-keto reductase-like protein 0.0028 0.013 0.0121
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0023 0.009 0.0136
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0112 0.0112
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0017 0.0036 0.0174
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0033
Giardia lamblia Aldose reductase 0.0028 0.013 0.0634
Schistosoma mansoni hypothetical protein 0.0121 0.0991 0.1339
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0068 0.0502 0.12
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0316 0.0721
Trypanosoma brucei heat shock protein 90, putative 0.0027 0.0124 0.0114
Schistosoma mansoni opsin-like receptor 0.0027 0.0122 0.0156
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0224
Brugia malayi PHD-finger family protein 0.0028 0.0134 0.0139
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.015 0.0142
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Echinococcus granulosus dro:myosuppressin receptor 0.0027 0.0122 0.0122
Mycobacterium leprae Conserved hypothetical protein 0.0023 0.009 0.0332
Schistosoma mansoni hypothetical protein 0.0027 0.0122 0.0156
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0028 0.013 0.0245
Echinococcus multilocularis dnaJ subfamily B 0.0811 0.7355 0.7355
Echinococcus multilocularis transfer RNA-Lys 0.0034 0.0189 0.0189
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0023 0.009 0.0136
Echinococcus multilocularis GPI anchor transamidase 0.0119 0.0975 0.0975
Echinococcus multilocularis neutral alpha glucosidase AB 0.0031 0.0163 0.0163
Echinococcus granulosus histone lysine methyltransferase setb 0.0047 0.0311 0.0311
Trypanosoma cruzi heat shock protein 90, putative 0.0016 0.0022 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Onchocerca volvulus 0.0028 0.013 0.0266
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.003 0.015 0.0291
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0021 0.0072 0.0668
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0087 0.015
Trypanosoma cruzi heat shock protein 90, putative 0.0027 0.0124 0.0114
Trypanosoma brucei polo-like protein kinase 0.0097 0.0765 0.0792
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0014 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0197 0.041
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0765 0.7674
Brugia malayi RE15519p 0.0027 0.0122 0.0127
Brugia malayi Peptidase C13 family protein 0.0514 0.4617 0.4872
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0197 0.0389
Brugia malayi Doublecortin family protein 0.0019 0.0047 0.0048
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Loa Loa (eye worm) peptidase C13 family protein 0.0514 0.4617 0.4873
Echinococcus multilocularis 0.0018 0.0037 0.0037
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0889 0.9046
Wolbachia endosymbiont of Brugia malayi cell division protein FtsI 0.0192 0.1643 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0068 0.0502 0.12
Mycobacterium tuberculosis Possible penicillin-binding lipoprotein 0.0189 0.1619 0.4085
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0122 0.0156
Mycobacterium ulcerans oxidoreductase 0.0028 0.013 0.0241
Echinococcus granulosus g protein coupled receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0112 0.0905 0.0905
Schistosoma mansoni neuropeptide f receptor 76f 0.0027 0.0122 0.0156
Loa Loa (eye worm) norepinephrine transporter 0.0085 0.0656 0.0692
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0889 0.9046
Schistosoma mansoni zinc finger protein 0.0015 0.0016 0.0011
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Echinococcus multilocularis Squalene phytoene synthase 0.0146 0.122 0.122
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0073 0.0121
Onchocerca volvulus 0.0085 0.0656 0.1406
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Echinococcus granulosus 6 phosphofructokinase 0.011 0.0889 0.0889
Schistosoma mansoni chromobox protein 0.0058 0.0408 0.0545
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis neuropeptide receptor A26 0.0027 0.0122 0.0122
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0027 0.0122 0.0156
Loa Loa (eye worm) hypothetical protein 0.0106 0.085 0.0897
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0078 0.0131
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0889 0.12
Loa Loa (eye worm) hypothetical protein 0.0146 0.122 0.1288
Echinococcus multilocularis orexin receptor type 2 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0085 0.0656 0.0692
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0023 0.009 0.0136
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2008 0.4328
Echinococcus granulosus lamin dm0 0.0051 0.0343 0.0343
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0008 0.0006
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0014 0.0008 0.0008
Mycobacterium leprae POSSIBLE PENICILLIN-BINDING LIPOPROTEIN 0.0189 0.1619 1
Echinococcus granulosus lamin 0.0051 0.0343 0.0343
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0058 0.0522
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.009 0.0078
Leishmania major C-8 sterol isomerase-like protein 0.1041 0.9475 1
Plasmodium falciparum thioredoxin reductase 0.003 0.015 0.147
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0027 0.0122 0.0156
Mycobacterium ulcerans bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 0.0022 0.0078 0.0104
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Onchocerca volvulus 0.0028 0.013 0.0266
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0437 0.3909 0.4116
Brugia malayi putative neuropeptide receptor NPR1 0.0027 0.0122 0.0127
Schistosoma mansoni hypothetical protein 0.0027 0.0122 0.0156
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Plasmodium falciparum endoplasmin, putative 0.0017 0.0028 0.0207
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0119 0.0975 0.1317
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0023 0.009 0.0136
Brugia malayi Cytochrome P450 family protein 0.0023 0.009 0.0093
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0122 0.0156
Schistosoma mansoni alpha glucosidase 0.0031 0.0163 0.0211
Schistosoma mansoni opsin-like receptor 0.0027 0.0122 0.0156
Schistosoma mansoni rab6-interacting 0.0019 0.0047 0.0054
Brugia malayi Serotonin receptor 0.0027 0.0122 0.0127
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Trypanosoma cruzi phytoene synthase, putative 0.0146 0.122 0.1274
Schistosoma mansoni cpg binding protein 0.0062 0.0448 0.0599
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0163 0.0316
Echinococcus multilocularis allatostatin A receptor 0.0027 0.0122 0.0122
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0023 0.009 0.0136
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0437 0.3909 0.4116
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0008 0.0006
Mycobacterium tuberculosis Probable dehydrogenase 0.0068 0.0502 0.12
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0316 0.0648
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Onchocerca volvulus 0.0027 0.0122 0.0248
Brugia malayi cytoplasmic intermediate filament protein 0.0027 0.0126 0.0131
Echinococcus multilocularis lysosomal alpha glucosidase 0.0141 0.1171 0.1171
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0018 0.0037 0.004
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni amine GPCR 0.0027 0.0122 0.0156
Loa Loa (eye worm) hypothetical protein 0.0028 0.013 0.0138
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0122 0.0122
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0016 0.0026 0.0019
Echinococcus multilocularis protoporphyrinogen oxidase 0.0018 0.0037 0.0037
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0047 0.005
Echinococcus multilocularis serotonin transporter 0.0085 0.0656 0.0656
Schistosoma mansoni hypothetical protein 0.0049 0.0327 0.0435
Echinococcus multilocularis lamin 0.0051 0.0343 0.0343
Echinococcus granulosus nuclear factor of activated T cells 5 0.0069 0.0509 0.0509
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trypanosoma cruzi aldo/keto reductase, putative 0.0028 0.013 0.0121
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0028 0.013 0.059
Trypanosoma brucei cytochrome P450, putative 0.0023 0.009 0.0078
Echinococcus multilocularis chromobox protein 1 0.0058 0.0408 0.0408
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0027 0.0122 0.0122
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0437 0.3909 0.4116
Schistosoma mansoni hypothetical protein 0.0049 0.0327 0.0435
Schistosoma mansoni lipoxygenase 0.0078 0.0595 0.0799
Chlamydia trachomatis transglycolase/transpeptidase 0.0022 0.0078 0.0428
Brugia malayi Serotonin receptor 0.0027 0.0122 0.0127
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0124 0.0114
Entamoeba histolytica phosphofructokinase, putative 0.011 0.0889 0.9046
Onchocerca volvulus 0.0028 0.013 0.0266
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Onchocerca volvulus Huntingtin homolog 0.0106 0.085 0.1827
Echinococcus granulosus thioredoxin glutathione reductase 0.003 0.0154 0.0154
Schistosoma mansoni heat shock protein 0.0027 0.0124 0.0158
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1041 0.9475 1
Schistosoma mansoni hypothetical protein 0.0019 0.0047 0.0054
Leishmania major hypothetical protein, conserved 0.0146 0.122 0.1274
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Chlamydia trachomatis transglycolase/transpeptidase 0.0192 0.1643 1
Leishmania major cytochrome p450-like protein 0.0023 0.009 0.0078
Leishmania major cytochrome p450-like protein 0.0023 0.009 0.0078
Mycobacterium ulcerans phytoene synthase, CrtB 0.0146 0.122 0.3056
Brugia malayi hypothetical protein 0.002 0.0058 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0302 0.0302
Echinococcus multilocularis Protein lozenge 0.0052 0.0354 0.0354
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0327 0.0327
Mycobacterium tuberculosis Probable reductase 0.0068 0.0502 0.12
Loa Loa (eye worm) hypothetical protein 0.0119 0.0975 0.103
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Mycobacterium ulcerans putative regulatory protein 0.0034 0.0189 0.0393
Loa Loa (eye worm) thioredoxin reductase 0.003 0.015 0.0158
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0014 0.0008 0.0008
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Toxoplasma gondii heat shock protein HSP90 0.0027 0.0124 0.1201
Trypanosoma cruzi squalene monooxygenase, putative 0.0155 0.1308 0.1366
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.002 0.0058 0.0061
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0027 0.0122 0.0127
Schistosoma mansoni amine GPCR 0.0027 0.0122 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Onchocerca volvulus 0.0414 0.3689 0.7985
Toxoplasma gondii peptidase c13 family protein 0.0119 0.0975 1
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0014 0.0008 0.0006
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0025 0.0104 0.0998
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0163 0.0316
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0149 0.0841
Giardia lamblia Aldose reductase 0.0028 0.013 0.0634
Loa Loa (eye worm) hypothetical protein 0.0051 0.0343 0.0362
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.0145 0.1211 0.1278
Schistosoma mansoni alpha-glucosidase 0.0121 0.0991 0.1338
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0047 0.0047
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0023 0.009 0.0136
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0163 0.0316
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0076 0.0572 0.1381
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.004 0.0241 0.0318
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Loa Loa (eye worm) neuropeptide F receptor 0.0027 0.0122 0.0129
Mycobacterium tuberculosis Probable penicillin-binding protein PbpA 0.0128 0.1056 0.2631
Trypanosoma brucei squalene synthase, putative 0.0468 0.4191 0.4414
Loa Loa (eye worm) histone methyltransferase 0.0019 0.0047 0.005
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0047 0.0409
Onchocerca volvulus 0.0027 0.0122 0.0248
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0021 0.0071 0.0059
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0889 0.0939
Schistosoma mansoni rab6-interacting 0.0019 0.0047 0.0054
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Brugia malayi Dopamine receptor protein 2 0.0027 0.0122 0.0127
Brugia malayi G-protein coupled receptor 0.0027 0.0122 0.0127
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus granulosus chromobox protein 1 0.0058 0.0408 0.0408
Brugia malayi Pre-SET motif family protein 0.003 0.0154 0.0161
Echinococcus granulosus 7TM GPCR rhodopsin 0.0027 0.0122 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0087 0.015
Schistosoma mansoni hypothetical protein 0.0106 0.0852 0.115
Brugia malayi hypothetical protein 0.0014 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0765 0.1031
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trypanosoma brucei glucosidase, putative 0.0031 0.0163 0.0155
Echinococcus multilocularis thioredoxin glutathione reductase 0.003 0.0154 0.0154
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0058 0.0522
Loa Loa (eye worm) hypothetical protein 0.0147 0.1229 0.1297
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Plasmodium vivax SET domain protein, putative 0.003 0.0154 0.1512
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0302 0.04
Echinococcus granulosus cpg binding protein 0.0062 0.0448 0.0448
Loa Loa (eye worm) intermediate filament protein 0.0051 0.0343 0.0362
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.013 0.1076 0.1121
Schistosoma mansoni endoplasmin 0.0027 0.0124 0.0158
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0022 0.0076 0.008
Echinococcus multilocularis microtubule associated protein 2 0.0544 0.4888 0.4888
Brugia malayi phosphofructokinase 0.011 0.0889 0.0937
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0047 0.0047
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Onchocerca volvulus 0.0027 0.0122 0.0248
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0018 0.0037 0.004
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0889 0.0923
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0023 0.009 0.0136
Onchocerca volvulus 0.0028 0.013 0.0266
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0122 0.0122
Entamoeba histolytica heat shock protein 90, putative 0.0027 0.0124 0.0583
Echinococcus multilocularis fmrfamide receptor 0.0027 0.0122 0.0122
Brugia malayi heat shock protein 90 0.0027 0.0124 0.0129
Echinococcus granulosus dnaJ subfamily B 0.0811 0.7355 0.7355
Loa Loa (eye worm) hypothetical protein 0.0025 0.0109 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0311 0.0412
Schistosoma mansoni aldo-keto reductase 0.0028 0.013 0.0167
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0163 0.0316
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0154 0.1512
Mycobacterium ulcerans heat shock protein 90 0.0021 0.0073 0.0093
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) solute carrier family 6 member 4 0.0085 0.0656 0.0692
Leishmania major trypanothione reductase 0.003 0.015 0.0142
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0122 0.0122
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0027 0.0122 0.0122
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0027 0.0122 0.0156
Brugia malayi putative neuropeptide receptor 0.0027 0.0122 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Entamoeba histolytica aldose reductase, putative 0.0028 0.013 0.0655
Leishmania major squalene synthase, putative 0.0468 0.4191 0.4414
Echinococcus multilocularis 0.0023 0.009 0.009
Echinococcus granulosus sodium and chloride dependent glycine 0.0014 0.0008 0.0008
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0085 0.0656 0.0882
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0023 0.009 0.0136
Schistosoma mansoni kinase 0.0049 0.0327 0.0435
Schistosoma mansoni hypothetical protein 0.0049 0.0327 0.0435
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Echinococcus multilocularis aldo keto reductase 0.0028 0.013 0.013
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Onchocerca volvulus 0.0147 0.1229 0.2649
Onchocerca volvulus 0.0027 0.0122 0.0248
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0023 0.009 0.0136
Onchocerca volvulus 0.0027 0.0122 0.0248
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0081 0.0139
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0047 0.0047
Schistosoma mansoni lamin 0.0051 0.0343 0.0456
Loa Loa (eye worm) heat shock protein 90 0.0027 0.0124 0.0131
Plasmodium vivax heat shock protein 86, putative 0.0027 0.0124 0.1201
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0437 0.3909 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Onchocerca volvulus 0.0027 0.0122 0.0248
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Echinococcus granulosus G protein coupled receptor 139 0.0027 0.0122 0.0122
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0027 0.0122 0.0122
Brugia malayi hypothetical protein 0.0019 0.0047 0.0048
Schistosoma mansoni lozenge 0.0052 0.0354 0.0471
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Toxoplasma gondii aldehyde dehydrogenase 0.0048 0.0316 0.3188
Chlamydia trachomatis protoporphyrinogen oxidase 0.0018 0.0037 0.018
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0302 0.0319
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0027 0.0122 0.0122
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0065 0.0068
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Brugia malayi Dopamine receptor 0.0027 0.0122 0.0127
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1098 1 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0525 0.0554
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0302 0.0302
Giardia lamblia Heat shock protein HSP 90-alpha 0.0027 0.0124 0.0561
Echinococcus multilocularis aldehyde reductase 0.002 0.0057 0.0057
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Schistosoma mansoni hemoglobinase (C13 family) 0.0514 0.4617 0.6274
Schistosoma mansoni hypothetical protein 0.0023 0.009 0.0112
Loa Loa (eye worm) cytochrome P450 0.0023 0.009 0.0095
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Brugia malayi sulfakinin receptor protein 0.0027 0.0122 0.0127
Brugia malayi Cytochrome P450 family protein 0.0041 0.0256 0.0269
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0022 0.0076 0.0078
Schistosoma mansoni hypothetical protein 0.0049 0.0327 0.0435
Schistosoma mansoni cytochrome P450 0.0023 0.009 0.0112
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0765 0.1643
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0122 0.0156
Brugia malayi GPI-anchor transamidase 0.0119 0.0975 0.1028
Toxoplasma gondii LsmAD domain-containing protein 0.002 0.0058 0.0522
Toxoplasma gondii heat shock protein 90, putative 0.0027 0.0124 0.1201
Onchocerca volvulus 0.0018 0.0037 0.0064
Onchocerca volvulus 0.0019 0.0047 0.0086
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1041 0.9475 1
Leishmania major squalene monooxygenase-like protein 0.0155 0.1308 0.1366
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0071 0.0059
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0048 0.0316 0.0316
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0019 0.0047 0.0047
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0023 0.009 0.0136
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.0902 0.9237
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus multilocularis aldo keto reductase 0.0028 0.013 0.013
Mycobacterium leprae PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE 0.0022 0.0078 0.0256
Echinococcus multilocularis expressed protein 0.0022 0.0076 0.0076
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0133 0.0133
Entamoeba histolytica GPI-anchor transamidase, putative 0.0119 0.0975 1
Onchocerca volvulus 0.0051 0.0343 0.0727
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0023 0.009 0.0136
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0028 0.013 0.0121
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0889 0.1895
Onchocerca volvulus 0.0081 0.0625 0.1339
Brugia malayi Intermediate filament tail domain containing protein 0.0051 0.0343 0.036
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.0889 0.2201
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0015 0.0015
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Echinococcus granulosus intermediate filament protein 0.0051 0.0343 0.0343
Schistosoma mansoni aldehyde dehydrogenase 0.0048 0.0316 0.042
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0408 0.0849
Brugia malayi PAS domain containing protein 0.0046 0.03 0.0315
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0163 0.1012
Echinococcus granulosus neuropeptide s receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Plasmodium vivax thioredoxin reductase, putative 0.003 0.015 0.147
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0021 0.0073 0.0093
Trichomonas vaginalis chromobox protein, putative 0.0058 0.0408 0.0849
Brugia malayi Cytochrome P450 family protein 0.0023 0.009 0.0093
Echinococcus multilocularis jun protein 0.0149 0.1249 0.1249
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Echinococcus multilocularis heat shock protein 90 0.0027 0.0124 0.0124
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0021 0.0072 0.0668
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0027 0.0122 0.0129
Onchocerca volvulus 0.0034 0.0189 0.0394
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0454 0.0454
Echinococcus granulosus lysine specific histone demethylase 1A 0.0018 0.0037 0.0037
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0085 0.0656 0.069
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0023 0.009 0.0136
Echinococcus multilocularis sodium and chloride dependent glycine 0.0014 0.0008 0.0008
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0122 0.0122
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0122 0.0156
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Schistosoma mansoni growth hormone secretagogue receptor 0.0027 0.0122 0.0156
Echinococcus granulosus expressed protein 0.0022 0.0076 0.0076
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0027 0.0122 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0023 0.009 0.0136
Brugia malayi glutathione reductase 0.003 0.015 0.0156
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Treponema pallidum sodium- and chloride- dependent transporter 0.0085 0.0656 0.3711
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Giardia lamblia Kinase, PLK 0.0097 0.0765 0.7669
Brugia malayi Dopamine receptor protein 1 0.0027 0.0122 0.0127
Schistosoma mansoni alpha-1 adrenergic receptor 0.0027 0.0122 0.0156
Brugia malayi Thioredoxin reductase 0.003 0.015 0.0156
Plasmodium vivax glutathione reductase, putative 0.003 0.015 0.147
Brugia malayi amine oxidase, flavin-containing family protein 0.0018 0.0037 0.0037
Loa Loa (eye worm) TYRA-2 protein 0.0027 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.0024 0.0092 0.0097
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0021 0.0072 0.0668
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0014 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0302 0.04
Echinococcus granulosus serotonin transporter 0.0085 0.0656 0.0656
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0018 0.0037 0.0037
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0027 0.0122 0.0156
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0014 0.0008 0.0008
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0124 0.0114
Treponema pallidum penicillin-binding protein (pbp-3) 0.0086 0.0665 0.3767
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0174 0.034
Schistosoma mansoni sodium/chloride dependent transporter 0.0015 0.0011 0.0004
Schistosoma mansoni endoplasmin 0.0027 0.0124 0.0158
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Brugia malayi GnHR receptor homolog 0.0027 0.0122 0.0127
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.009 0.0136
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0122 0.0122
Echinococcus granulosus tm gpcr rhodopsin 0.0027 0.0122 0.0122
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0027 0.0122 0.0156
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0122 0.0122
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0149 0.1462
Mycobacterium tuberculosis Possible oxidoreductase 0.0021 0.0072 0.0091
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1751 0.1848
Schistosoma mansoni biogenic amine receptor 0.0027 0.0122 0.0156
Echinococcus multilocularis G-protein coupled receptor, putative 0.0027 0.0122 0.0122
Schistosoma mansoni polycystin 1-related 0.0019 0.0047 0.0054
Brugia malayi G protein-coupled receptor F59B2.13 0.0027 0.0122 0.0127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.005
Trypanosoma brucei Emopamil binding protein, putative 0.013 0.1076 0.1121
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0014 0.0008 0.0008
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0852 0.0898
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0019 0.0047 0.005
Schistosoma mansoni jun-related protein 0.0121 0.0991 0.1339
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0327 0.0327
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0047 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.04 0.0423
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0287 0.252 0.3419
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trypanosoma cruzi squalene synthase, putative 0.0468 0.4191 0.4414
Leishmania major cytochrome p450-like protein 0.0023 0.009 0.0078
Echinococcus multilocularis zinc finger protein 0.0023 0.0085 0.0085
Brugia malayi Bromodomain containing protein 0.0038 0.0227 0.0238
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Trichomonas vaginalis aldo/keto reductase, putative 0.0028 0.013 0.0245
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0023 0.009 0.0136
Brugia malayi CHD4 protein 0.0015 0.001 0.0009
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0027 0.0122 0.0129
Echinococcus granulosus hypothetical protein 0.0027 0.0122 0.0122
Brugia malayi AKH receptor 0.0027 0.0122 0.0127
Plasmodium falciparum glutathione reductase 0.003 0.015 0.147
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0032 0.0032
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0141 0.1171 0.1236
Loa Loa (eye worm) hypothetical protein 0.1041 0.9475 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0027 0.0122 0.0122
Brugia malayi 6-phosphofructokinase 0.011 0.0889 0.0937
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0027 0.0122 0.0122
Schistosoma mansoni sodium/chloride dependent transporter 0.0085 0.0656 0.0882
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.001 0.001
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.0889 0.0889
Echinococcus granulosus aldo keto reductase 0.0028 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus granulosus g protein coupled receptor 0.0027 0.0122 0.0122
Entamoeba histolytica aldose reductase, putative 0.0028 0.013 0.0655
Mycobacterium leprae putative cytochrome p450 0.0023 0.009 0.0332
Echinococcus multilocularis neuropeptide receptor 0.0027 0.0122 0.0122
Entamoeba histolytica aldose reductase, putative 0.0028 0.013 0.0655
Leishmania major ATP-dependent phosphofructokinase 0.011 0.0889 0.0923
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0149 0.0286
Loa Loa (eye worm) hypothetical protein 0.0155 0.1305 0.1377
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0302 0.0317
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0027 0.0122 0.0156
Loa Loa (eye worm) melatonin receptor type 1A 0.0027 0.0122 0.0129
Brugia malayi cytochrome P450 0.0023 0.009 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0092 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Schistosoma mansoni single-minded 0.0046 0.03 0.0398
Echinococcus multilocularis sodium and chloride dependent glycine 0.0014 0.0008 0.0008
Schistosoma mansoni intermediate filament proteins 0.0051 0.0343 0.0456
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0019 0.0047 0.0047
Plasmodium falciparum protoporphyrinogen oxidase 0.0018 0.0037 0.0305
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0302 0.0302
Onchocerca volvulus 0.0025 0.0109 0.0221
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0302 0.0302
Brugia malayi CXXC zinc finger family protein 0.0057 0.04 0.0421
Trichomonas vaginalis aldo/keto reductase, putative 0.0028 0.013 0.0245
Echinococcus granulosus 7tm_1 domain containing protein 0.0027 0.0122 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Brugia malayi ORL1-like opioid receptor 0.0027 0.0122 0.0127
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0889 0.1895
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0027 0.0122 0.0156
Trypanosoma brucei C-8 sterol isomerase, putative 0.1041 0.9475 1
Loa Loa (eye worm) transcription factor SMAD2 0.0094 0.0742 0.0783
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0085 0.0656 0.0692
Loa Loa (eye worm) hypothetical protein 0.0085 0.0656 0.0692
Schistosoma mansoni neuropeptide receptor 0.0027 0.0122 0.0156
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0027 0.0122 0.0156
Echinococcus multilocularis g protein coupled receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis neuropeptide s receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0027 0.0122 0.0129
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0023 0.009 0.0136
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0889 0.1895
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0027 0.0122 0.0122
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0224
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0163 0.0155
Trichomonas vaginalis rotamase, putative 0.0022 0.0076 0.0127
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0037 0.0305
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0076 0.0572 0.338
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0027 0.0122 0.0122
Brugia malayi Heterochromatin protein 1 0.0058 0.0408 0.0429
Trichomonas vaginalis sucrase-isomaltase, putative 0.0031 0.0163 0.0316
Echinococcus granulosus aldo keto reductase 0.0028 0.013 0.013
Brugia malayi hypoxia-induced factor 1 0.0143 0.119 0.1254
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0023 0.009 0.0078
Echinococcus granulosus sex peptide receptor 0.0027 0.0122 0.0122
Schistosoma mansoni amine oxidase 0.0018 0.0037 0.004
Schistosoma mansoni biogenic amine receptor 0.0027 0.0122 0.0156
Trypanosoma cruzi heat shock protein 85, putative 0.0027 0.0124 0.0114
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0122 0.0129
Brugia malayi hypothetical protein 0.0106 0.085 0.0895
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Giardia lamblia GPI-anchor transamidase, putative 0.0119 0.0975 1
Treponema pallidum penicillin-binding protein (pbp-2) 0.0022 0.0078 0.0028
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0021 0.0073 0.0228
Schistosoma mansoni amine GPCR 0.0027 0.0122 0.0156
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Echinococcus multilocularis cpg binding protein 0.0062 0.0448 0.0448
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0149 0.0862
Brugia malayi 6-phosphofructokinase 0.011 0.0889 0.0937
Echinococcus granulosus lysosomal alpha glucosidase 0.0141 0.1171 0.1171
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Echinococcus multilocularis somatostatin receptor 0.0027 0.0122 0.0122
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.1305 0.1375
Schistosoma mansoni neuropeptide receptor 0.0027 0.0122 0.0156
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Schistosoma mansoni neuropeptide receptor 0.0027 0.0122 0.0156
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Treponema pallidum penicillin-binding protein (pbp-1) 0.0192 0.1643 1
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0119 0.0975 0.2083
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0327 0.0346
Echinococcus granulosus aldo keto reductase 0.0028 0.013 0.013
Brugia malayi Tachykinin-like peptides receptor 99D 0.0027 0.0122 0.0127
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0149 0.1462
Brugia malayi hypothetical protein 0.0023 0.0091 0.0095
Schistosoma mansoni lipoxygenase 0.0112 0.0905 0.1221
Loa Loa (eye worm) endoplasmin 0.0027 0.0124 0.0131
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0028 0.013 0.0136
Schistosoma mansoni aldehyde dehydrogenase 0.0048 0.0316 0.042
Schistosoma mansoni hypothetical protein 0.0023 0.0091 0.0114
Trypanosoma brucei trypanothione reductase 0.003 0.015 0.0142
Echinococcus granulosus neuropeptide receptor 0.0027 0.0122 0.0122
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0027 0.0122 0.0127
Loa Loa (eye worm) hypoxia-induced factor 1 0.0143 0.119 0.1256
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0327 0.0327
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0021 0.0071 0.0059
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni transcription factor LCR-F1 0.0023 0.0091 0.0114
Trichomonas vaginalis heat shock protein, putative 0.0017 0.0028 0.0022
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0146 0.122 0.3056
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0031 0.0163 0.0172
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0765 0.0792
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0112 0.0905 0.0905
Loa Loa (eye worm) hypothetical protein 0.0049 0.0327 0.0346
Trypanosoma brucei PAB1-binding protein , putative 0.002 0.0058 0.0045
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0033
Echinococcus granulosus geminin 0.0287 0.252 0.252
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0048 0.0316 0.0318
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0037 0.004
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.001 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0058 0.0045
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis g-protein coupled receptor 0.0027 0.0122 0.0122
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Onchocerca volvulus 0.0028 0.013 0.0266
Echinococcus multilocularis GPCR, family 2 0.0049 0.0327 0.0327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.009 0.0078
Echinococcus multilocularis neuropeptides capa receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0023 0.009 0.0136
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0027 0.0122 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0023 0.009 0.0136
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0027 0.0122 0.0127
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0765 0.0806
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0224
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0014 0.0008 0.0008
Trypanosoma cruzi squalene monooxygenase, putative 0.0155 0.1308 0.1366
Brugia malayi G-protein coupled receptor 0.0027 0.0122 0.0127
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0048 0.0316 0.0721
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0765 0.0792
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0027 0.0122 0.0122
Entamoeba histolytica heat shock protein 90, putative 0.0027 0.0124 0.0583
Plasmodium vivax endoplasmin, putative 0.0027 0.0124 0.1201
Plasmodium falciparum heat shock protein 90 0.0027 0.0124 0.1201
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0028 0.013 0.0121
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0081 0.0139
Loa Loa (eye worm) oxidoreductase 0.0028 0.013 0.0138
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0028 0.013 0.0136
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0149 0.1462
Leishmania major hypothetical protein, conserved 0.013 0.1076 0.1121
Schistosoma mansoni biogenic amine (5HT) receptor 0.0027 0.0122 0.0156
Echinococcus granulosus tachykinin peptides receptor 99D 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0041 0.0249 0.0263
Echinococcus multilocularis musashi 0.0051 0.0343 0.0343
Echinococcus granulosus serotonin receptor 0.0027 0.0122 0.0122
Onchocerca volvulus 0.0027 0.0122 0.0248
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0197 0.0389
Loa Loa (eye worm) hypothetical protein 0.0038 0.0228 0.024
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0063 0.0065
Echinococcus granulosus endoplasmin 0.0021 0.0073 0.0073
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0122 0.0156
Mycobacterium ulcerans penicillin-binding membrane protein PbpB 0.0086 0.0665 0.1621
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0024 0.0101 0.0101
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0119 0.0975 0.2083
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0119 0.0975 0.2083
Schistosoma mansoni lamin 0.0051 0.0343 0.0456
Schistosoma mansoni hypothetical protein 0.0027 0.0122 0.0156
Brugia malayi Glycosyl hydrolases family 31 protein 0.0141 0.1171 0.1234
Echinococcus granulosus orexin receptor type 2 0.0027 0.0122 0.0122
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0174 0.0361
Schistosoma mansoni 6-phosphofructokinase 0.011 0.0889 0.12
Schistosoma mansoni loxhd1 0.0019 0.0047 0.0054
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Onchocerca volvulus 0.0019 0.0047 0.0086
Brugia malayi Cytochrome P450 family protein 0.0023 0.009 0.0093
Mycobacterium tuberculosis Probable oxidoreductase 0.0076 0.0572 0.1381
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0437 0.3909 0.4116
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0205 0.0205
Brugia malayi bZIP transcription factor family protein 0.0149 0.1249 0.1316
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0024 0.0101 0.0101
Plasmodium falciparum GPI-anchor transamidase, putative 0.0119 0.0975 1
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Loa Loa (eye worm) MH2 domain-containing protein 0.0094 0.0742 0.0783
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0149 0.1249 0.1249
Leishmania major UDP-galactopyranose mutase 0.0018 0.0037 0.0023
Schistosoma mansoni microtubule-associated protein tau 0.0544 0.4888 0.6642
Echinococcus multilocularis serotonin receptor 0.0027 0.0122 0.0122
Brugia malayi bHLH-PAS transcription factor 0.0034 0.0189 0.0198
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0023 0.009 0.0136
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0047 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni amine GPCR 0.0027 0.0122 0.0156
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Loa Loa (eye worm) hypothetical protein 0.0155 0.13 0.1372
Onchocerca volvulus 0.0027 0.0122 0.0248
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0027 0.0122 0.0122
Brugia malayi MH2 domain containing protein 0.0094 0.0742 0.0782
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.0889 0.0939
Onchocerca volvulus Legumain homolog 0.0514 0.4617 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0023 0.009 0.0136
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0023 0.009 0.0136
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0023 0.009 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0047 0.0311 0.0412
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0149 0.0865
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0051 0.0343 0.0362
Trypanosoma brucei heat shock protein 90, putative 0.0027 0.0124 0.0114
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0058 0.0045
Onchocerca volvulus Huntingtin homolog 0.0106 0.085 0.1827
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.009 0.0095
Schistosoma mansoni rotamase 0.0022 0.0076 0.0093
Echinococcus granulosus neuropeptide receptor A26 0.0027 0.0122 0.0122
Echinococcus granulosus jun protein 0.0149 0.1249 0.1249
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus multilocularis chromobox protein 1 0.0058 0.0408 0.0408
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Echinococcus granulosus heat shock protein 90 0.0021 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.0889 0.2201
Schistosoma mansoni neuropeptide receptor 0.0027 0.0122 0.0156
Echinococcus granulosus chromobox protein 1 0.0058 0.0408 0.0408
Loa Loa (eye worm) heterochromatin protein 1 0.0058 0.0408 0.0431
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) hypothetical protein 0.0414 0.3689 0.3893
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0149 0.0286
Trypanosoma cruzi Emopamil binding protein, putative 0.013 0.1076 0.1121
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0765 0.0765
Echinococcus multilocularis aldo keto reductase 0.0028 0.013 0.013
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0021 0.0073 0.0061
Mycobacterium tuberculosis Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen 0.0022 0.0078 0.0104
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Mycobacterium leprae PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN 0.0022 0.0078 0.0256
Brugia malayi intermediate filament protein 0.0051 0.0343 0.036
Schistosoma mansoni hemoglobinase (C13 family) 0.0514 0.4617 0.6274
Brugia malayi hypothetical protein 0.0147 0.1229 0.1295
Schistosoma mansoni hypothetical protein 0.0395 0.3517 0.4776
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0047 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0023 0.009 0.0136
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0514 0.4617 1
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0076 0.0572 0.1381
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.0889 0.5387
Echinococcus granulosus hypothetical protein 0.0028 0.013 0.013
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0514 0.4617 0.6274
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.0889 0.1895
Brugia malayi hypothetical protein 0.0018 0.0037 0.0037
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0027 0.0122 0.0122
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0119 0.0975 0.1015
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Brugia malayi chromobox protein homolog 3 0.0032 0.0174 0.0182
Mycobacterium ulcerans aldehyde dehydrogenase 0.0048 0.0316 0.0721
Loa Loa (eye worm) hypothetical protein 0.0047 0.0311 0.0328
Onchocerca volvulus Neuropeptide F receptor homolog 0.0027 0.0122 0.0248
Mycobacterium tuberculosis Probable oxidoreductase 0.0028 0.013 0.0241
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0048 0.0316 0.0316
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0027 0.0122 0.0127
Mycobacterium ulcerans penicillin-binding protein PbpA 0.0128 0.1056 0.2631
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0149 0.1249 0.1249
Schistosoma mansoni hypothetical protein 0.0027 0.0122 0.0156
Plasmodium vivax GPI-anchor transamidase, putative 0.0119 0.0975 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0023 0.0091 0.0091
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.1305 0.1375
Echinococcus granulosus neutral alpha glucosidase AB 0.0031 0.0163 0.0163
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0027 0.0126 0.0133
Onchocerca volvulus 0.0231 0.2009 0.4342
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0014 0.0008 0.0006
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0327 0.0344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Onchocerca volvulus 0.004 0.0241 0.0507
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0028 0.013 0.0136
Echinococcus multilocularis aldo keto reductase 0.0028 0.013 0.013
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0765 0.0792
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0027 0.0122 0.0156
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0028 0.013 0.0136
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0302 0.04
Onchocerca volvulus 0.0027 0.0122 0.0248
Schistosoma mansoni cpg binding protein 0.0062 0.0448 0.0599
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0174 0.034
Schistosoma mansoni bromodomain containing protein 0.0066 0.0486 0.0652
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus granulosus fmrfamide receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis sex peptide receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis heat shock protein 90 0.0021 0.0073 0.0073
Trichomonas vaginalis aldo/keto reductase, putative 0.0028 0.013 0.0245
Echinococcus granulosus aldehyde reductase 0.002 0.0057 0.0057
Mycobacterium ulcerans bifunctional penicillin-binding protein 1A/1B PonA1 0.0022 0.0078 0.0104
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0027 0.0122 0.0156
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0454 0.0454
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0149 0.1462
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0149 0.1462
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0205 0.0205
Brugia malayi neuropeptide F receptor 0.0027 0.0122 0.0127
Trypanosoma cruzi UDP-galactopyranose mutase 0.0021 0.0072 0.006
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0149 0.0865
Loa Loa (eye worm) hypothetical protein 0.005 0.0334 0.0353
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Onchocerca volvulus 0.0027 0.0122 0.0248
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.009 0.0095
Brugia malayi Endoplasmin precursor 0.0027 0.0124 0.0129
Loa Loa (eye worm) hypothetical protein 0.0532 0.4782 0.5047
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0163 0.0316
Trypanosoma cruzi Emopamil binding protein, putative 0.013 0.1076 0.1121
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Echinococcus granulosus heat shock protein 90 0.0027 0.0124 0.0124
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.001 0.001
Onchocerca volvulus 0.0028 0.013 0.0266
Echinococcus granulosus RUN 0.0019 0.0047 0.0047
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0014 0.0008 0.0008
Trichomonas vaginalis endoplasmin, putative 0.0017 0.0028 0.0022
Echinococcus granulosus single minded 2 0.0034 0.0189 0.0189
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0073 0.0121
Toxoplasma gondii aldose reductase, putative 0.0028 0.013 0.1269
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Plasmodium vivax ataxin-2 like protein, putative 0.002 0.0058 0.0522
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0245 0.213 0.2248
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0047 0.0409
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0023 0.009 0.0136
Leishmania major alpha glucosidase II subunit, putative 0.0031 0.0163 0.0155
Schistosoma mansoni myosin xvIII 0.0027 0.0122 0.0156
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0023 0.0091 0.0091
Brugia malayi Pre-SET motif family protein 0.0203 0.1751 0.1846
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0018 0.0037 0.0305
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.0889 0.0923
Loa Loa (eye worm) hypothetical protein 0.0106 0.0852 0.09
Echinococcus multilocularis neuropeptide FF receptor 2 0.0027 0.0122 0.0122
Schistosoma mansoni adenoreceptor 0.0027 0.0122 0.0156
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0015 0.0015
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0327 0.0344
Echinococcus granulosus cytochrome P450 2K1 0.0023 0.009 0.009
Leishmania major hypothetical protein, conserved 0.002 0.0058 0.0045
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0023 0.009 0.0136
Brugia malayi Melatonin receptor type 1A 0.0027 0.0122 0.0127
Echinococcus granulosus allatostatin A receptor 0.0027 0.0122 0.0122
Echinococcus granulosus GPI anchor transamidase 0.0119 0.0975 0.0975
Trichomonas vaginalis heat shock protein, putative 0.0027 0.0124 0.0231
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0149 0.0484
Loa Loa (eye worm) runx1 0.0052 0.0354 0.0373
Trypanosoma cruzi UDP-galactopyranose mutase 0.0018 0.0037 0.0023
Brugia malayi hypothetical protein 0.0414 0.3689 0.3892
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni opsin-like receptor 0.0027 0.0122 0.0156
Toxoplasma gondii cytochrome p450 superfamily protein 0.0023 0.009 0.0848
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0149 0.1462
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Entamoeba histolytica hypothetical protein 0.0023 0.0091 0.0224
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0037 0.0305
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0068 0.0502 0.2938
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0163 0.1012
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0765 0.0808
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0026 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0027 0.0122 0.0156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0765 0.1625
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0028 0.013 0.0245
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.001 0.0003
Echinococcus granulosus neuropeptides capa receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis neuropeptide Y receptor 0.0027 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0021 0.0065 0.0078
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0149 0.1462
Trichomonas vaginalis heat shock protein, putative 0.0021 0.0073 0.0121
Echinococcus granulosus g protein coupled receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni zinc finger protein 0.0023 0.0085 0.0105
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.0889 0.5198
Brugia malayi hypothetical protein 0.0027 0.0122 0.0127
Onchocerca volvulus 0.0051 0.0343 0.0727
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0023 0.009 0.0136
Brugia malayi hypothetical protein 0.0117 0.0954 0.1005
Loa Loa (eye worm) oxidoreductase 0.0028 0.013 0.0138
Schistosoma mansoni hypothetical protein 0.0811 0.7355 1
Loa Loa (eye worm) G-protein coupled receptor 0.0027 0.0122 0.0129
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0081 0.0139
Schistosoma mansoni aldo-keto reductase 0.0028 0.013 0.0167
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0028 0.013 0.013
Brugia malayi SWIRM domain containing protein 0.0018 0.0037 0.0037
Toxoplasma gondii peptidylprolyl isomerase 0.0021 0.0071 0.0656
Echinococcus granulosus somatostatin receptor 0.0027 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0015 0.0016 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0068 0.0502 0.12
Schistosoma mansoni neuropeptide F-like receptor 0.0027 0.0122 0.0156
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Loa Loa (eye worm) hypothetical protein 0.0046 0.0297 0.0313
Echinococcus granulosus g-protein coupled receptor 0.0027 0.0122 0.0122
Loa Loa (eye worm) oxidoreductase 0.0028 0.013 0.0138
Echinococcus multilocularis rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0163 0.017
Schistosoma mansoni amine GPCR 0.0027 0.0122 0.0156
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Schistosoma mansoni histamine h1 receptor 0.0027 0.0122 0.0156
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0023 0.009 0.0136
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0021 0.0073 0.0073
Echinococcus granulosus zinc finger protein 0.0023 0.0085 0.0085
Schistosoma mansoni amine oxidase 0.0021 0.0072 0.0088
Echinococcus granulosus peptide allatostatin:somatostatin 0.0027 0.0122 0.0122
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0023 0.009 0.0136
Echinococcus granulosus neuropeptide FF receptor 2 0.0027 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0106 0.085 0.0897
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0112 0.0142
Trypanosoma brucei heat shock protein, putative 0.0027 0.0124 0.0114
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Onchocerca volvulus 0.0027 0.0122 0.0248
Schistosoma mansoni heat shock protein 0.0027 0.0124 0.0158
Schistosoma mansoni biogenic amine receptor 0.0027 0.0122 0.0156
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0146 0.122 0.2631
Trypanosoma brucei squalene monooxygenase, putative 0.0155 0.1308 0.1366
Loa Loa (eye worm) hypothetical protein 0.0018 0.0037 0.0039
Brugia malayi follicle stimulating hormone receptor 0.0245 0.213 0.2247
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0027 0.0122 0.0248
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.0256 0.0271
Schistosoma mansoni hypothetical protein 0.0287 0.252 0.3419
Trichomonas vaginalis aldo-keto reductase, putative 0.0028 0.013 0.0245
Loa Loa (eye worm) oxidoreductase 0.0028 0.013 0.0138
Loa Loa (eye worm) glutathione reductase 0.003 0.015 0.0158
Echinococcus multilocularis heat shock protein 0.0027 0.0124 0.0124
Trypanosoma cruzi squalene synthase, putative 0.0468 0.4191 0.4414
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0999 0.1349
Loa Loa (eye worm) serotonin transporter b 0.0085 0.0656 0.0692
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0028 0.013 0.013
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0023 0.009 0.0136
Leishmania major heat shock protein 83-1 0.0027 0.0124 0.0114
Echinococcus multilocularis lysosomal alpha glucosidase 0.0141 0.1171 0.1171
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0154 0.0154
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0023 0.009 0.0136
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Echinococcus granulosus neuropeptide Y receptor 0.0027 0.0122 0.0122
Echinococcus multilocularis G protein coupled receptor 139 0.0027 0.0122 0.0122
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0163 0.0316
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0008
Echinococcus multilocularis dro:myosuppressin receptor 0.0027 0.0122 0.0122
Schistosoma mansoni chromobox protein 0.0058 0.0408 0.0545
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0021 0.0071 0.0059
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0023 0.009 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0076 0.0127
Schistosoma mansoni alpha-glucosidase 0.0121 0.0991 0.1338
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0028 0.013 0.0245
Echinococcus granulosus rhodopsin orphan GPCR 0.0027 0.0122 0.0122
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0119 0.0975 0.1015
Onchocerca volvulus 0.0057 0.04 0.0852
Echinococcus granulosus microtubule associated protein 2 0.0544 0.4888 0.4888
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0129
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0154 0.0199
Brugia malayi larval opioid receptor 0.0027 0.0122 0.0127
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0437 0.3909 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0163 0.0316
Brugia malayi neuropeptide F receptor 0.0027 0.0122 0.0127

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.