Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0174 | 0.6916 | 0.6916 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0224 | 1 | 1 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0224 | 1 | 0.5 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0108 | 0.283 | 0.283 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Echinococcus granulosus | proteasome prosome macropain | 0.0224 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0174 | 0.6916 | 0.6916 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0224 | 1 | 1 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0108 | 0.283 | 0.283 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0108 | 0.283 | 0.283 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0062 | 0 | 0.5 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0224 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0174 | 0.6916 | 0.5699 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0224 | 1 | 0.5 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0224 | 1 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0174 | 0.6916 | 0.6916 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0174 | 0.6916 | 0.5699 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.6916 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0224 | 1 | 1 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0224 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 2 | 0.0108 | 0.283 | 0.283 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0174 | 0.6916 | 0.5699 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0224 | 1 | 1 |
Mycobacterium ulcerans | proteasome PrcB | 0.0224 | 1 | 0.5 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0224 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0174 | 0.6916 | 0.5699 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0224 | 1 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0174 | 0.6916 | 0.5699 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0174 | 0.6916 | 0.5699 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 | |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0174 | 0.6916 | 0.5699 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0108 | 0.283 | 0.283 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0108 | 0.283 | 0.283 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0062 | 0 | 0.5 |
Brugia malayi | proteasome subunit beta type 1 | 0.0174 | 0.6916 | 0.6916 |
Onchocerca volvulus | 0.0062 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.