Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Proteasome A-type and B-type family protein | 0.0523 | 0.5487 | 0.5487 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0406 | 0.3964 | 0.7224 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0406 | 0.3964 | 0.7224 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0252 | 0.1946 | 0.1946 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0868 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0406 | 0.3964 | 0.7224 |
Leishmania major | hypothetical protein, conserved | 0.0162 | 0.0777 | 0.0777 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0523 | 0.5487 | 0.5487 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0252 | 0.1946 | 0.3546 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0406 | 0.3964 | 0.3964 |
Trypanosoma cruzi | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0162 | 0.0777 | 0.0777 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0523 | 0.5487 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0523 | 0.5487 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0252 | 0.1946 | 0.3546 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0406 | 0.3964 | 0.3964 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0406 | 0.3964 | 0.7224 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0523 | 0.5487 | 1 |
Leishmania major | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0162 | 0.0777 | 0.0777 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0523 | 0.5487 | 0.5487 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0406 | 0.3964 | 0.3964 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0252 | 0.1946 | 0.1946 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0252 | 0.1946 | 0.3546 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0252 | 0.1946 | 0.3546 |
Loa Loa (eye worm) | hypothetical protein | 0.0868 | 1 | 1 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0523 | 0.5487 | 1 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0523 | 0.5487 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0523 | 0.5487 | 0.5487 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0523 | 0.5487 | 0.5487 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0523 | 0.5487 | 1 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0252 | 0.1946 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0406 | 0.3964 | 0.7224 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0868 | 1 | 1 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0252 | 0.1946 | 0.1946 |
Trypanosoma cruzi | Emopamil binding protein, putative | 0.0162 | 0.0777 | 0.0777 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0868 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0444 | 0.4455 | 0.4455 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0252 | 0.1946 | 0.3546 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0523 | 0.5487 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0406 | 0.3964 | 0.3964 |
Trypanosoma cruzi | 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative | 0.0162 | 0.0777 | 0.0777 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0523 | 0.5487 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0252 | 0.1946 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0252 | 0.1946 | 0.3546 |
Onchocerca volvulus | 0.0162 | 0.0777 | 1 | |
Brugia malayi | proteasome subunit beta type 1 | 0.0406 | 0.3964 | 0.3964 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0406 | 0.3964 | 0.7224 |
Brugia malayi | proteasome subunit beta type 2 | 0.0252 | 0.1946 | 0.1946 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0406 | 0.3964 | 0.7224 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0523 | 0.5487 | 0.5487 |
Trypanosoma brucei | Emopamil binding protein, putative | 0.0162 | 0.0777 | 0.0777 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0252 | 0.1946 | 0.1946 |
Trypanosoma cruzi | Emopamil binding protein, putative | 0.0162 | 0.0777 | 0.0777 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.0103 | 0 | 0.5 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0252 | 0.1946 | 0.1946 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0406 | 0.3964 | 0.7224 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0406 | 0.3964 | 0.7224 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0252 | 0.1946 | 0.3546 |
Mycobacterium ulcerans | proteasome PrcB | 0.0523 | 0.5487 | 1 |
Echinococcus granulosus | proteasome prosome macropain | 0.0523 | 0.5487 | 1 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0523 | 0.5487 | 1 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0523 | 0.5487 | 1 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0406 | 0.3964 | 0.3964 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0252 | 0.1946 | 0.3546 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0252 | 0.1946 | 0.3546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.