Detailed information for compound 843791

Basic information

Technical information
  • TDR Targets ID: 843791
  • Name: 3-(4-fluorophenyl)-1-propyl-1-(thiophen-2-ylm ethyl)urea
  • MW: 292.372 | Formula: C15H17FN2OS
  • H donors: 1 H acceptors: 1 LogP: 3.31 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN(C(=O)Nc1ccc(cc1)F)Cc1cccs1
  • InChi: 1S/C15H17FN2OS/c1-2-9-18(11-14-4-3-10-20-14)15(19)17-13-7-5-12(16)6-8-13/h3-8,10H,2,9,11H2,1H3,(H,17,19)
  • InChiKey: DGTNAKOGDBUITM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(4-fluorophenyl)-1-propyl-1-(2-thienylmethyl)urea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus tyrosine protein kinase shark 0.0068 0.0583 0.0583
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0089 0.2929 0.2929
Schistosoma mansoni septate junction protein 0.0089 0.2929 0.3629
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0069 0.0624 0.0624
Echinococcus multilocularis leucine rich repeats and immunoglobulin 0.0069 0.0624 0.0624
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0081 0.1945 0.1945
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Echinococcus granulosus nephrin 0.0069 0.0624 0.0624
Onchocerca volvulus Tyrosine kinase homolog 0.0115 0.5766 1
Echinococcus multilocularis Opioid binding protein:cell adhesion molecule 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus neuroglian 0.0132 0.7695 0.7695
Brugia malayi Animal haem peroxidase family protein 0.0069 0.0624 0.0837
Onchocerca volvulus Netrin receptor homolog 0.0069 0.0624 0.0078
Brugia malayi protein-tyrosine kinase 0.0068 0.0583 0.0783
Echinococcus multilocularis neuroglian 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Echinococcus granulosus lachesin 0.0089 0.2929 0.2929
Echinococcus multilocularis titin 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Schistosoma mansoni subfamily M23B non-peptidase homologue (M23 family) 0.0069 0.0624 0.0773
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Echinococcus granulosus tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0089 0.2929 0.2929
Echinococcus granulosus leucine rich repeats and immunoglobulin 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus titin 0.0069 0.0624 0.0624
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0069 0.0624 0.0624
Onchocerca volvulus 0.0069 0.0624 0.0078
Brugia malayi SRC-1 0.0068 0.0583 0.0783
Echinococcus granulosus insulin growth factor binding 0.0069 0.0624 0.0624
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Schistosoma mansoni cell adhesion molecule 0.0069 0.0624 0.0773
Schistosoma mansoni cell adhesion molecule 0.0089 0.2929 0.3629
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Onchocerca volvulus 0.0069 0.0624 0.0078
Schistosoma mansoni cell adhesion molecule 0.0069 0.0624 0.0773
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus multilocularis transfer RNA-Phe 0.0069 0.0624 0.0624
Brugia malayi kettin 0.0069 0.0624 0.0837
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0624 0.0773
Echinococcus granulosus tyrosine kinase 0.0068 0.0583 0.0583
Brugia malayi hypothetical protein 0.0068 0.0583 0.0783
Onchocerca volvulus 0.0069 0.0624 0.0078
Schistosoma mansoni roundabout 0.0089 0.2929 0.3629
Schistosoma mansoni titin 0.0089 0.2929 0.3629
Brugia malayi Protein kinase domain containing protein 0.0068 0.0583 0.0783
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.1352 0.5
Echinococcus granulosus titin 0.0069 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase shark 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Brugia malayi Protein kinase domain containing protein 0.0068 0.0583 0.0783
Brugia malayi Tyrosine-protein kinase abl-1 0.0068 0.0583 0.0783
Onchocerca volvulus Peroxidasin homolog 0.0069 0.0624 0.0078
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0089 0.2929 0.3629
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0081 0.1945 0.1945
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0084 0.2305 0.2305
Schistosoma mansoni neuroglian 0.0089 0.2929 0.3629
Echinococcus granulosus titin 0.0069 0.0624 0.0624
Onchocerca volvulus 0.0069 0.0624 0.0078
Loa Loa (eye worm) TK/ROR protein kinase 0.0115 0.5766 0.5766
Echinococcus multilocularis roundabout 2 0.0089 0.2929 0.2929
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0089 0.2929 0.3629
Onchocerca volvulus 0.0069 0.0624 0.0078
Brugia malayi Prion-like- 0.0069 0.0624 0.0837
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Loa Loa (eye worm) hypothetical protein 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Echinococcus granulosus twitchin 0.0132 0.7695 0.7695
Echinococcus granulosus tyrosine protein kinase Srms 0.0068 0.0583 0.0583
Echinococcus multilocularis titin 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.007 0.0754 0.0754
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Brugia malayi Protein kinase domain containing protein 0.0068 0.0583 0.0783
Echinococcus multilocularis twitchin 0.0069 0.0624 0.0624
Brugia malayi SH2 domain containing protein 0.0068 0.0583 0.0783
Echinococcus multilocularis peroxidasin 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus multilocularis titin 0.0069 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Schistosoma mansoni cell adhesion molecule 0.0089 0.2929 0.3629
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Schistosoma mansoni septate junction protein 0.0089 0.2929 0.3629
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.013 0.7448 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0069 0.0624 0.0624
Onchocerca volvulus 0.0069 0.0624 0.0078
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Loa Loa (eye worm) disorganized muscle protein 1 0.0069 0.0624 0.0624
Onchocerca volvulus 0.0069 0.0624 0.0078
Echinococcus granulosus tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus multilocularis hemicentin 1 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) TK protein kinase 0.0115 0.5766 0.5766
Schistosoma mansoni nephrin 0.0132 0.7695 0.9533
Echinococcus multilocularis insulin growth factor binding 0.0069 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Brugia malayi Peroxidasin 0.0089 0.2929 0.3932
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Brugia malayi protein unc-22 0.0069 0.0624 0.0837
Echinococcus multilocularis 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Schistosoma mansoni cell adhesion molecule 0.0084 0.2305 0.2856
Brugia malayi Myb-like DNA-binding domain containing protein 0.0069 0.0624 0.0837
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.5766 0.7742
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus multilocularis tyrosine protein kinase Abl 0.0068 0.0583 0.0583
Brugia malayi SH2 domain containing protein 0.0068 0.0583 0.0783
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0068 0.0583 0.0583
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Echinococcus multilocularis down syndrome cell adhesion 0.0069 0.0624 0.0624
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0068 0.0583 0.0722
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.2773 0.3436
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0089 0.2929 0.2929
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0089 0.2929 0.2929
Echinococcus multilocularis titin 0.0069 0.0624 0.0624
Brugia malayi Disorganized muscle protein 1 0.0069 0.0624 0.0837
Brugia malayi Protein kinase domain containing protein 0.0068 0.0583 0.0783
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0068 0.0583 0.0583
Echinococcus granulosus tyrosine protein kinase Lyn 0.0068 0.0583 0.0583
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0089 0.2929 0.2929
Echinococcus multilocularis neuroglian 0.0132 0.7695 0.7695
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus granulosus tyrosine protein kinase Blk 0.0068 0.0583 0.0583
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0068 0.0583 0.0583
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Echinococcus granulosus peroxidasin 0.0089 0.2929 0.2929
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Schistosoma mansoni voltage-gated potassium channel 0.0088 0.2773 0.3436
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Schistosoma mansoni cell adhesion molecule 0.0069 0.0624 0.0773
Onchocerca volvulus Peroxidasin homolog 0.0069 0.0624 0.0078
Echinococcus multilocularis tyrosine kinase 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0084 0.2305 0.2305
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0068 0.0583 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0068 0.0583 0.0583
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0068 0.0583 0.0583
Echinococcus multilocularis tyrosine protein kinase Blk 0.0068 0.0583 0.0583
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0115 0.5766 0.5766
Schistosoma mansoni myosin-binding protein-related 0.0069 0.0624 0.0773
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0075 0.1352 0.5
Brugia malayi Prion-like- 0.0089 0.2929 0.3932
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0081 0.1945 0.1945
Echinococcus multilocularis roundabout 2 0.0089 0.2929 0.2929
Schistosoma mansoni cell adhesion molecule 0.0089 0.2929 0.3629
Brugia malayi Prion-like- 0.0069 0.0624 0.0837
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0089 0.2929 0.2929
Schistosoma mansoni hemicentin 0.0069 0.0624 0.0773
Loa Loa (eye worm) projectin 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Schistosoma mansoni slit 0.0069 0.0624 0.0773
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Loa Loa (eye worm) TK/KIN16 protein kinase 0.013 0.7448 0.7448
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Brugia malayi Leucine Rich Repeat family protein 0.0069 0.0624 0.0837
Echinococcus multilocularis roundabout 2 0.0153 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0069 0.0624 0.0773
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Schistosoma mansoni nephrin 0.0089 0.2929 0.3629
Onchocerca volvulus 0.0069 0.0624 0.0078
Echinococcus granulosus hemicentin 1 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0153 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Echinococcus granulosus tyrosine protein kinase Src42A 0.0068 0.0583 0.0583
Echinococcus multilocularis tyrosine protein kinase Srms 0.0068 0.0583 0.0583
Onchocerca volvulus 0.0069 0.0624 0.0078
Echinococcus granulosus contactin 0.0089 0.2929 0.2929
Loa Loa (eye worm) TK protein kinase 0.0068 0.0583 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Onchocerca volvulus 0.0069 0.0624 0.0078
Schistosoma mansoni vesicular amine transporter 0.0068 0.0593 0.0735
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0089 0.2929 0.4526
Loa Loa (eye worm) animal heme peroxidase 0.0069 0.0624 0.0624
Loa Loa (eye worm) CAMK protein kinase 0.0069 0.0624 0.0624
Echinococcus multilocularis c src tyrosine kinase 0.0068 0.0583 0.0583
Echinococcus granulosus down syndrome cell adhesion 0.0069 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase otk 0.0089 0.2929 0.2929
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Echinococcus granulosus titin 0.0069 0.0624 0.0624
Echinococcus granulosus neuroglian 0.0089 0.2929 0.2929
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0068 0.0583 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus multilocularis lachesin 0.0089 0.2929 0.2929
Echinococcus granulosus tyrosine protein kinase ABL1 0.0068 0.0583 0.0583
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0068 0.0583 0.0583
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0081 0.1945 0.2611
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Brugia malayi Protein kinase domain containing protein 0.0068 0.0583 0.0783
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0089 0.2929 0.2929
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0153 1 1
Echinococcus multilocularis hemicentin 1 0.0089 0.2929 0.2929
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Onchocerca volvulus Putative titin 0.0069 0.0624 0.0078
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0068 0.0583 0.0583
Echinococcus granulosus roundabout 2 0.0089 0.2929 0.2929
Echinococcus granulosus leucine rich repeat containing protein 4 0.0069 0.0624 0.0624
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Schistosoma mansoni tyrosine kinase 0.0135 0.8072 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0089 0.2929 0.2929
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Loa Loa (eye worm) SRC-1 0.0068 0.0583 0.0583
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0089 0.2929 0.2929
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Echinococcus granulosus tyrosine kinase 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Brugia malayi Wrapper/rega-1/klingon homolog protein 1 0.0069 0.0624 0.0837
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Echinococcus granulosus tyrosine protein kinase Src64B 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0089 0.2929 0.2929
Echinococcus granulosus Opioid binding protein:cell adhesion molecule 0.0069 0.0624 0.0624
Loa Loa (eye worm) one IG domain family member 0.0069 0.0624 0.0624
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0068 0.0583 0.0583
Loa Loa (eye worm) hypothetical protein 0.0069 0.0624 0.0624
Loa Loa (eye worm) TK/ABL protein kinase 0.0068 0.0583 0.0583
Echinococcus granulosus titin 0.0069 0.0624 0.0624
Schistosoma mansoni hypothetical protein 0.0069 0.0624 0.0773
Onchocerca volvulus 0.0069 0.0624 0.0078
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus c src tyrosine kinase 0.0068 0.0583 0.0583
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0068 0.0583 0.0583
Schistosoma mansoni tyrosine kinase 0.0068 0.0583 0.0722
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus granulosus tyrosine protein kinase otk 0.0089 0.2929 0.2929
Schistosoma mansoni nephrin related 0.0069 0.0624 0.0773
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Brugia malayi Prion-like- 0.0069 0.0624 0.0837
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0069 0.0624 0.0624
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0068 0.0583 0.5
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.2929 0.3932
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0583 0.0583
Brugia malayi Immunoglobulin I-set domain containing protein 0.0069 0.0624 0.0837
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0068 0.0583 0.0583
Echinococcus granulosus roundabout 2 0.0089 0.2929 0.2929
Loa Loa (eye worm) TK/FER protein kinase 0.0068 0.0583 0.0583
Schistosoma mansoni titin 0.0069 0.0624 0.0773
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0115 0.5766 0.5766

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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