Detailed information for compound 899485

Basic information

Technical information
  • TDR Targets ID: 899485
  • Name: 5-amino-3-hexylsulfanyl-1H-[1,2,4]triazolo[4, 5-a]pyrimidin-7-one
  • MW: 267.351 | Formula: C11H17N5OS
  • H donors: 2 H acceptors: 4 LogP: 3.34 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCSc1nnc2n1c(N)cc(n2)O
  • InChi: 1S/C11H17N5OS/c1-2-3-4-5-6-18-11-15-14-10-13-9(17)7-8(12)16(10)11/h7H,2-6,12H2,1H3,(H,13,14,17)
  • InChiKey: UPMYLUSDBROLEO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-amino-3-(hexylthio)-1H-[1,2,4]triazolo[4,5-a]pyrimidin-7-one
  • MLS000704563
  • SMR000231899
  • ZINC01803476
  • AP-906/41642040
  • 5-amino-3-(hexylsulfanyl)[1,2,4]triazolo[4,3-a]pyrimidin-7(8H)-one

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Candida albicans hypothetical protein Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references
Homo sapiens snurportin 1 No references
Homo sapiens hydroxyprostaglandin dehydrogenase 15-(NAD) Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium falciparum steroid dehydrogenase, putative hydroxyprostaglandin dehydrogenase 15-(NAD) 266 aa 216 aa 22.2 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1481 0.2276 0.2275
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0151 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0057 0.0065 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.054 0.0816 0.0814
Echinococcus granulosus microtubule associated protein 2 0.4056 0.6277 0.6276
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0052 0.0058 0.0984
Echinococcus granulosus para nitrobenzyl esterase 0.0106 0.0142 0.014
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0048 0.0052 0.0146
Entamoeba histolytica transcription factor BTF3, putative 0.0083 0.0106 0.0459
Echinococcus multilocularis X box binding protein 1 0.0227 0.033 0.0328
Onchocerca volvulus 0.0106 0.0142 0.0617
Toxoplasma gondii NADPH-glutathione reductase 0.0019 0.0006 0.0017
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0109 0.0147 0.2673
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0108 0.0144 0.0142
Loa Loa (eye worm) hypothetical protein 0.0133 0.0184 0.0182
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Trypanosoma brucei metacaspase 0.0019 0.0006 0.0016
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Loa Loa (eye worm) hypothetical protein 0.0103 0.0136 0.0135
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0058 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0049 0.0133
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.005 0.0055 0.0936
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Brugia malayi intermediate filament protein 0.011 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1053 0.1612 0.456
Echinococcus multilocularis lamin 0.011 0.0147 0.0145
Brugia malayi RNA, U transporter 1 0.0099 0.0131 0.0131
Onchocerca volvulus Serine\/threonine kinase homolog 0.0093 0.0122 0.0528
Brugia malayi Furin-like cysteine rich region family protein 0.0979 0.1497 0.1497
Toxoplasma gondii histone lysine methyltransferase SET1 0.0237 0.0345 0.0977
Echinococcus granulosus polycomb protein SCMH1 0.0082 0.0103 0.0102
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0037 0.0035
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0108 0.0144 0.0144
Echinococcus granulosus neuropeptide s receptor 0.1032 0.1579 0.1578
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0151 0.0212 0.0212
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.054 0.0816 0.0816
Brugia malayi Papain family cysteine protease containing protein 0.0853 0.1302 0.1302
Schistosoma mansoni hypothetical protein 0.1237 0.1898 0.1898
Echinococcus granulosus FTZ F1 alpha 0.0151 0.0212 0.021
Brugia malayi PHD-finger family protein 0.0028 0.0021 0.0021
Echinococcus multilocularis cathepsin b 0.6453 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0059 0.0069 0.0069
Echinococcus granulosus X box binding protein 1 0.0227 0.033 0.0328
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Trypanosoma brucei protein kinase, putative 0.0037 0.0034 0.0097
Echinococcus granulosus Polycystic kidney disease protein 0.0061 0.0072 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0019 0.0006 0.0006
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0242 0.0352 0.035
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0141 0.0196 0.0194
Schistosoma mansoni heat shock protein 0.0039 0.0038 0.0038
Brugia malayi Doublecortin family protein 0.0061 0.0072 0.0072
Schistosoma mansoni zinc finger protein 0.0053 0.0059 0.0059
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0049 0.0052 0.0222
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0425 0.0637 0.18
Leishmania major cathepsin L-like protease 0.2278 0.3516 0.9951
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0151 0.0212 0.0212
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0021 0.0019
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0017 0.0015
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0144 0.0144
Brugia malayi PHD-finger family protein 0.0093 0.0122 0.0122
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0088 0.0086
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0151 0.0212 0.021
Plasmodium falciparum thioredoxin reductase 0.0019 0.0006 0.0018
Brugia malayi mbt repeat family protein 0.0082 0.0103 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0093 0.0122 0.0122
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0059 0.0057
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0049 0.0047
Schistosoma mansoni nuclear receptor 0.0071 0.0088 0.0088
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Loa Loa (eye worm) bromodomain containing protein 0.0061 0.0072 0.007
Echinococcus multilocularis neuropeptide s receptor 0.1032 0.1579 0.1578
Loa Loa (eye worm) carboxylesterase 0.063 0.0956 0.0954
Schistosoma mansoni sex comb on midleg homolog 0.0082 0.0103 0.0103
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0041 0.004 0.0167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Brugia malayi nuclear receptor RXR 0.0071 0.0088 0.0088
Onchocerca volvulus 0.0058 0.0066 0.0284
Onchocerca volvulus 0.0061 0.0072 0.0309
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0144 0.0144
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0125 0.0171 0.0169
Echinococcus multilocularis snurportin 1 0.0372 0.0554 0.0552
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.007 0.0085 0.0083
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0679 0.1031 0.292
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0425 0.0637 0.0637
Echinococcus multilocularis acetylcholinesterase 0.063 0.0956 0.0954
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0019 0.0006 0.0017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0046 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0853 0.1302 0.3682
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0425 0.0637 0.0637
Echinococcus multilocularis BC026374 protein (S09 family) 0.0106 0.0142 0.014
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0006 0.0017
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0107 0.0144 0.0142
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0151 0.0212 0.021
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0043 0.0044 0.0715
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0026 0.0024
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0106 0.0142 0.0398
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0247 0.036 0.1014
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0093 0.0122 0.034
Trypanosoma cruzi cruzipain precursor, putative 0.0428 0.0641 0.064
Brugia malayi cathepsin L-like precursor 0.1053 0.1612 0.1612
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0025 0.0067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0056 0.0064 0.0063
Trypanosoma brucei beta lactamase 0.0052 0.0058 0.0165
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0095 0.0125 0.0354
Trypanosoma cruzi heat shock protein 90, putative 0.0031 0.0025 0.0024
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0056 0.0064 0.0182
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0109 0.0147 0.2673
Echinococcus granulosus endoplasmin 0.0031 0.0025 0.0024
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0019 0.0006 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0058 0.0056
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0014 0.0035
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0247 0.036 0.672
Echinococcus multilocularis cathepsin b 0.6453 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Loa Loa (eye worm) hypothetical protein 0.0061 0.0072 0.007
Echinococcus multilocularis endoplasmin 0.0031 0.0025 0.0024
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0044 0.0118
Schistosoma mansoni steroid hormone receptor ad4bp 0.0151 0.0212 0.0212
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Echinococcus multilocularis thyroid hormone receptor alpha 0.0151 0.0212 0.021
Onchocerca volvulus 0.0638 0.0967 0.4244
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0021 0.0053
Schistosoma mansoni microtubule-associated protein tau 0.4056 0.6277 0.6277
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0425 0.0637 0.18
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0151 0.0212 0.0212
Trypanosoma cruzi cysteine peptidase, putative 0.1481 0.2276 0.2275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Trypanosoma cruzi trypanothione reductase, putative 0.0054 0.0061 0.0059
Leishmania major cathepsin L-like protease 0.2278 0.3516 0.9951
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0093 0.0121 0.0119
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0019 0.0006 0.0018
Brugia malayi Smad1 0.0019 0.0006 0.0006
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0043 0.0044 0.0042
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0022 0.0011 0.0042
Trypanosoma cruzi heat shock protein 85, putative 0.0031 0.0025 0.0024
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0853 0.1302 0.1302
Toxoplasma gondii exonuclease III APE 0.0043 0.0044 0.0123
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0071 0.0088 0.0088
Brugia malayi steroid hormone receptor 0.0151 0.0212 0.0212
Schistosoma mansoni hypothetical protein 0.0369 0.055 0.055
Schistosoma mansoni hypothetical protein 0.0171 0.0242 0.0242
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0116 0.0158 0.0156
Loa Loa (eye worm) hypothetical protein 0.0032 0.0027 0.0025
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0023 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0021 0.0019
Entamoeba histolytica Ran family GTPase 0.0026 0.0017 0.0065
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Loa Loa (eye worm) glutathione reductase 0.0054 0.0061 0.0059
Brugia malayi ecdysone receptor 0.0071 0.0088 0.0088
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0071 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Leishmania major mitochondrial DNA polymerase beta 0.0679 0.1031 0.2916
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Echinococcus granulosus BC026374 protein S09 family 0.0106 0.0142 0.014
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0006 0.0004
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Loa Loa (eye worm) hypothetical protein 0.0428 0.0641 0.064
Brugia malayi hypothetical protein 0.0071 0.0088 0.0088
Giardia lamblia Kinase, PLK 0.0093 0.0122 0.0329
Mycobacterium ulcerans glutaminase 0.0232 0.0337 0.6296
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0049 0.0138
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0141 0.0196 0.0194
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0268 0.0393 0.0391
Leishmania major hypothetical protein, conserved 0.0019 0.0006 0.0011
Brugia malayi Carboxylesterase family protein 0.0106 0.0142 0.0142
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0046 0.0048 0.0048
Trichomonas vaginalis glutaminase, putative 0.0232 0.0337 0.095
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0151 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Plasmodium falciparum serine repeat antigen 6 0.0425 0.0637 0.2794
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0021 0.0053
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0053 0.0059 0.0057
Echinococcus granulosus cathepsin l1 0.1053 0.1612 0.161
Schistosoma mansoni hypothetical protein 0.1237 0.1898 0.1898
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Loa Loa (eye worm) inositol-1 0.0056 0.0064 0.0063
Onchocerca volvulus 0.0151 0.0212 0.0923
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Echinococcus multilocularis RUN 0.0061 0.0072 0.007
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0034 0.009
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0006 0.0004
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Giardia lamblia Grp94/Hsp90 0.0031 0.0025 0.0055
Trichomonas vaginalis CMGC family protein kinase 0.0037 0.0034 0.0092
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.6453 1 1
Schistosoma mansoni hypothetical protein 0.0171 0.0242 0.0242
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0106 0.0142 0.014
Loa Loa (eye worm) MBCTL1 0.0093 0.0121 0.0119
Schistosoma mansoni jumonji domain containing protein 0.0039 0.0038 0.0038
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0041 0.004 0.004
Schistosoma mansoni cathepsin F (C01 family) 0.1481 0.2276 0.2276
Echinococcus granulosus insulin receptor 0.0313 0.0463 0.0461
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Onchocerca volvulus 0.0018 0.0004 0.0011
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0052 0.0058 0.0056
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0108 0.0144 0.0142
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0026 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1481 0.2276 0.6442
Echinococcus granulosus neuroligin 0.0106 0.0142 0.014
Schistosoma mansoni intermediate filament proteins 0.011 0.0147 0.0147
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Echinococcus multilocularis cathepsin L 0.0425 0.0637 0.0636
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0151 0.0212 0.0212
Trypanosoma cruzi metacaspase, putative 0.0019 0.0006 0.0004
Onchocerca volvulus Alhambra homolog 0.0046 0.0048 0.0202
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0071 0.0088 0.0088
Echinococcus granulosus phd:f box containing protein 0.0039 0.0038 0.0036
Toxoplasma gondii hypothetical protein 0.011 0.0147 0.0416
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0056 0.0064 0.111
Brugia malayi Thioredoxin reductase 0.0054 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.1053 0.1612 0.161
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.033 0.0489 0.0488
Loa Loa (eye worm) glutaminase 0.0232 0.0337 0.0336
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Onchocerca volvulus Protein ultraspiracle homolog 0.0151 0.0212 0.0923
Schistosoma mansoni hypothetical protein 0.0046 0.0048 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.1481 0.2276 1
Trypanosoma cruzi transcription factor btf3, putative 0.0083 0.0106 0.0105
Loa Loa (eye worm) steroid hormone receptor 0.0151 0.0212 0.021
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0124 0.0169 0.5206
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0046 0.0049 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0052 0.0058 0.0246
Loa Loa (eye worm) Smad1 0.0019 0.0006 0.0004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0048 0.0052 0.005
Onchocerca volvulus 0.0364 0.0543 0.2378
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0038 0.0036
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0151 0.0212 0.021
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0088 0.0088
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0313 0.0463 0.0461
Echinococcus granulosus transcription factor Dp 1 0.0027 0.0018 0.0017
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Entamoeba histolytica cysteine proteinase, putative 0.0853 0.1302 0.5715
Brugia malayi jmjC domain containing protein 0.0039 0.0038 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.0037 0.0034 0.0092
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1481 0.2276 0.6442
Schistosoma mansoni endoplasmin 0.0039 0.0038 0.0038
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0037 0.0034 0.0097
Toxoplasma gondii thioredoxin reductase 0.0054 0.0061 0.0173
Schistosoma mansoni BC026374 protein (S09 family) 0.0106 0.0142 0.0142
Schistosoma mansoni phosphatidylserine receptor 0.0039 0.0038 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0212 0.0212
Entamoeba histolytica hypothetical protein 0.0083 0.0106 0.0459
Trypanosoma cruzi cysteine peptidase, putative 0.2278 0.3516 0.3514
Echinococcus multilocularis 0.0303 0.0447 0.0446
Trypanosoma cruzi major cysteine proteinase, putative 0.1223 0.1876 0.1875
Brugia malayi hypothetical protein 0.0071 0.0088 0.0088
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Loa Loa (eye worm) hypothetical protein 0.0034 0.003 0.0028
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0092 0.012 0.3449
Brugia malayi nuclear hormone receptor family member odr-7 0.0071 0.0088 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0151 0.0212 0.021
Brugia malayi glutathione reductase 0.0054 0.0061 0.0061
Plasmodium falciparum endoplasmin, putative 0.0024 0.0014 0.0055
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0041 0.004 0.0038
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0052 0.0058 0.0056
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0043 0.0044 0.0123
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 0.3608
Toxoplasma gondii PHD-finger domain-containing protein 0.0046 0.0048 0.0135
Onchocerca volvulus 0.0077 0.0097 0.0419
Loa Loa (eye worm) latrophilin receptor protein 2 0.0171 0.0242 0.024
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0019 0.0006 0.0017
Leishmania major cysteine peptidase A (CPA) 0.1481 0.2276 0.6442
Schistosoma mansoni cathepsin S (C01 family) 0.0425 0.0637 0.0637
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0044 0.0045 0.0043
Loa Loa (eye worm) DR-78 0.0071 0.0088 0.0086
Loa Loa (eye worm) transcription factor SMAD2 0.0275 0.0404 0.0402
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.0054
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0019 0.0006 0.0018
Trypanosoma brucei ISWI complex protein 0.0053 0.0059 0.0168
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0212 0.021
Plasmodium vivax serine-repeat antigen (SERA) 0.0425 0.0637 0.2794
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0037 0.0034 0.0032
Echinococcus multilocularis smad 0.0019 0.0006 0.0004
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0019 0.0006 0.0018
Giardia lamblia Cathepsin L-like protease 0.0425 0.0637 0.179
Leishmania major cathepsin L-like protease 0.1481 0.2276 0.6442
Brugia malayi Cell death protein 3 precursor 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0114 0.0153 0.0152
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 0.1302 0.3685
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0044 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0037 0.0034 0.0092
Brugia malayi Papain family cysteine protease containing protein 0.1481 0.2276 0.2276
Entamoeba histolytica cysteine proteinase, putative 0.0853 0.1302 0.5715
Onchocerca volvulus 0.0106 0.0142 0.0617
Brugia malayi hypothetical protein 0.0031 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0212 0.021
Brugia malayi ecdysteroid receptor 0.0151 0.0212 0.0212
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0853 0.1302 0.3682
Schistosoma mansoni SET domain protein 0.0018 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Brugia malayi hypothetical protein 0.0638 0.0967 0.0967
Echinococcus granulosus peptidase Clp S14 family 0.0092 0.012 0.0119
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0065
Trypanosoma cruzi metacaspase, putative 0.0019 0.0006 0.0004
Toxoplasma gondii cathepsin B 0.229 0.3533 1
Loa Loa (eye worm) hypothetical protein 0.1053 0.1612 0.161
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.003 0.0028
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0006 0.0004
Trypanosoma brucei polo-like protein kinase 0.0093 0.0122 0.0345
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0052 0.0058 0.0056
Leishmania major basic transcription factor 3a, putative 0.0083 0.0106 0.0296
Schistosoma mansoni smad1 5 8 and 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0006
Brugia malayi nuclear hormone receptor 0.0071 0.0088 0.0088
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0068 0.0066
Toxoplasma gondii cathepsin CPC1 0.0425 0.0637 0.1804
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0425 0.0637 0.2794
Loa Loa (eye worm) hypothetical protein 0.0141 0.0196 0.0194
Plasmodium falciparum importin beta, putative 0.0035 0.0031 0.0128
Echinococcus multilocularis lamin dm0 0.011 0.0147 0.0145
Loa Loa (eye worm) nuclear receptor NHR-67 0.0071 0.0088 0.0086
Giardia lamblia Heat shock protein HSP 90-alpha 0.0031 0.0025 0.0055
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0077 0.0097 0.0097
Brugia malayi RNA binding protein 0.0216 0.0313 0.0313
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0122 0.012
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0242 0.0352 0.035
Trypanosoma brucei metacaspase MCA2 0.0019 0.0006 0.0016
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0019 0.0006 0.0012
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0025 0.0067
Loa Loa (eye worm) RNA binding protein 0.0216 0.0313 0.0311
Brugia malayi hypothetical protein 0.0031 0.0025 0.0025
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0425 0.0637 0.0637
Schistosoma mansoni smad 0.0019 0.0006 0.0006
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0006 0.0017
Brugia malayi N-terminal motif family protein 0.0136 0.0189 0.0189
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0085 0.0109 0.0109
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0038 0.0036
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.008 0.0101 0.0099
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0853 0.1302 0.1302
Loa Loa (eye worm) hypothetical protein 0.008 0.0101 0.0099
Giardia lamblia Cathepsin B precursor 0.229 0.3533 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0037 0.0034 0.0032
Echinococcus multilocularis cysteine protease 0.1481 0.2276 0.2275
Schistosoma mansoni sex comb on midleg homolog 0.0082 0.0103 0.0103
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1256 0.1928 0.1927
Trypanosoma brucei trypanothione reductase 0.0054 0.0061 0.0173
Onchocerca volvulus 0.011 0.0147 0.0638
Loa Loa (eye worm) hypothetical protein 0.038 0.0566 0.0565
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0212 0.0212
Echinococcus multilocularis lysine specific demethylase 5A 0.0147 0.0205 0.0203
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0041 0.004 0.004
Echinococcus multilocularis Smad4 0.0019 0.0006 0.0004
Echinococcus granulosus PHD finger protein rhinoceros 0.0046 0.0048 0.0046
Schistosoma mansoni acetylcholinesterase 0.0106 0.0142 0.0142
Echinococcus multilocularis carboxylesterase 5A 0.063 0.0956 0.0954
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0052 0.0058 0.0246
Echinococcus granulosus cathepsin l1 0.1481 0.2276 0.2275
Echinococcus multilocularis cathepsin L cysteine protease 0.1481 0.2276 0.2275
Trypanosoma cruzi cysteine proteinase, putative 0.0853 0.1302 0.13
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0425 0.0637 0.0636
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0056 0.0064 0.0177
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0425 0.0637 0.2794
Trichomonas vaginalis set domain proteins, putative 0.0364 0.0543 0.1532
Toxoplasma gondii hypothetical protein 0.0049 0.0052 0.0148
Plasmodium falciparum serine repeat antigen 9 0.0425 0.0637 0.2794
Echinococcus granulosus fetal alzheimer antigen falz 0.0085 0.0109 0.0107
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0056 0.0064 0.0177
Onchocerca volvulus 0.0425 0.0637 0.2794
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0425 0.0637 0.18
Echinococcus granulosus importin subunit beta 1 0.0035 0.0031 0.0029
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Brugia malayi MH2 domain containing protein 0.0275 0.0404 0.0404
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0038 0.0102
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0425 0.0637 0.2794
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0017
Mycobacterium ulcerans aldehyde dehydrogenase 0.0247 0.036 0.672
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0006 0.0004
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Plasmodium falciparum cysteine proteinase falcipain 1 0.0853 0.1302 0.5715
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.003 0.003
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0151 0.0212 0.0212
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0151 0.0212 0.021
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0046 0.0049 0.0047
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0425 0.0637 0.179
Onchocerca volvulus Cathepsin F homolog 0.1481 0.2276 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0071 0.0088 0.0086
Loa Loa (eye worm) MH2 domain-containing protein 0.0275 0.0404 0.0402
Echinococcus granulosus cpg binding protein 0.0133 0.0184 0.0182
Brugia malayi MH1 domain containing protein 0.0019 0.0006 0.0006
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0425 0.0637 0.2794
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0023 0.0012 0.0012
Echinococcus multilocularis Polycystic kidney disease protein 0.0061 0.0072 0.007
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0171 0.0242 0.024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0019 0.0006 0.0006
Plasmodium vivax unspecified product 0.0853 0.1302 0.5715
Brugia malayi Probable ATP-dependent helicase DHX35 0.0114 0.0153 0.0153
Schistosoma mansoni zinc finger protein 0.0071 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.1053 0.1612 0.161
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0425 0.0637 0.0637
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0038 0.0036
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0321 0.0476 0.1343
Schistosoma mansoni zinc finger protein 0.0075 0.0093 0.0093
Plasmodium vivax unspecified product 0.0428 0.0641 0.2812
Mycobacterium ulcerans lipoprotein LpqF 0.0052 0.0058 0.0995
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.0047
Echinococcus granulosus epidermal growth factor receptor 0.0526 0.0794 0.0792
Toxoplasma gondii TIM10 family protein, putative 0.0041 0.004 0.0113
Echinococcus multilocularis caspase 2 0.0019 0.0006 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0043 0.0044 0.0184
Echinococcus multilocularis jumonji domain containing protein 0.0064 0.0076 0.0074
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0137 0.019 0.3501
Echinococcus granulosus expressed protein 0.0041 0.004 0.0038
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0052 0.0058 0.1197
Loa Loa (eye worm) hypothetical protein 0.0082 0.0103 0.0102
Loa Loa (eye worm) DEAH box polypeptide 35 0.0114 0.0153 0.0152
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0019 0.0006 0.0017
Echinococcus multilocularis peptidase Clp (S14 family) 0.0092 0.012 0.0119
Echinococcus multilocularis chromobox protein 1 0.0057 0.0066 0.0064
Plasmodium vivax ataxin-2 like protein, putative 0.0019 0.0006 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Giardia lamblia Encystation-specific protease 0.0425 0.0637 0.179
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0049 0.0052 0.073
Loa Loa (eye worm) jmjC domain-containing protein 0.0094 0.0123 0.0121
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.229 0.3533 1
Schistosoma mansoni glutaminase 0.0232 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Brugia malayi Endoplasmin precursor 0.0039 0.0038 0.0038
Loa Loa (eye worm) TK/EGFR protein kinase 0.0979 0.1497 0.1496
Echinococcus multilocularis ecdysone induced protein 78C 0.0151 0.0212 0.021
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0032 0.0027 0.011
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Echinococcus granulosus dnaJ subfamily B 0.1305 0.2004 0.2003
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0425 0.0637 0.0637
Schistosoma mansoni kinase 0.0048 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.008 0.0101 0.0099
Brugia malayi glutaminase DH11.1 0.0232 0.0337 0.0337
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0425 0.0637 0.18
Trypanosoma brucei transcription factor BTF3, putative 0.0083 0.0106 0.0301
Schistosoma mansoni hypothetical protein 0.0072 0.0088 0.0088
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0052 0.0058 0.0058
Schistosoma mansoni nuclear receptor 0.0071 0.0088 0.0088
Schistosoma mansoni loxhd1 0.0061 0.0072 0.0072
Entamoeba histolytica cysteine proteinase 1, putative 0.0853 0.1302 0.5715
Schistosoma mansoni aldehyde dehydrogenase 0.0247 0.036 0.036
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Schistosoma mansoni tar DNA-binding protein 0.0216 0.0313 0.0313
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0171 0.0242 0.024
Schistosoma mansoni rab6-interacting 0.0061 0.0072 0.0072
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0056 0.0064 0.0275
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0151 0.0212 0.021
Onchocerca volvulus Bile acid receptor homolog 0.0151 0.0212 0.0923
Plasmodium falciparum thioredoxin reductase 0.0054 0.0061 0.026
Brugia malayi CXXC zinc finger family protein 0.012 0.0163 0.0163
Brugia malayi fibroinase precursor 0.0425 0.0637 0.0637
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0106 0.0296
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 0.3608
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0137 0.019 0.3501
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0106 0.0142 0.2588
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0427 0.064 0.2808
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Brugia malayi orphan nuclear receptor NR2E1 0.0071 0.0088 0.0088
Trypanosoma brucei Metacaspase-4 0.0019 0.0006 0.0016
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0012 0.0029
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0425 0.0637 0.0637
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0425 0.0637 0.0637
Echinococcus granulosus RUN 0.0061 0.0072 0.007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0247 0.036 0.672
Toxoplasma gondii preprocathepsin c precursor, putative 0.0425 0.0637 0.1804
Brugia malayi SET domain containing protein 0.0018 0.0004 0.0004
Brugia malayi nuclear hormone receptor 0.0151 0.0212 0.0212
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.0554 0.0552
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1481 0.2276 0.2275
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Echinococcus multilocularis cysteine protease 0.1481 0.2276 0.2275
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0031 0.0025 0.102
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0092 0.012 0.2174
Echinococcus granulosus cathepsin b 0.6453 1 1
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Plasmodium falciparum cysteine proteinase falcipain 3 0.1481 0.2276 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0151 0.0212 0.0212
Brugia malayi hypothetical protein 0.0019 0.0006 0.0006
Echinococcus multilocularis neuropeptide receptor A26 0.1032 0.1579 0.1578
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0031 0.0082
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Plasmodium vivax vivapain-2 0.1481 0.2276 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0056 0.0064 0.3077
Loa Loa (eye worm) hypothetical protein 0.008 0.0101 0.0099
Echinococcus granulosus JmjC domain containing protein 4 0.0039 0.0038 0.0036
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0151 0.0212 0.021
Treponema pallidum fructose-bisphosphate aldolase 0.0427 0.064 1
Trypanosoma brucei Heat shock protein 83, putative 0.0039 0.0038 0.0107
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.229 0.3533 1
Entamoeba histolytica hypothetical protein 0.0425 0.0637 0.2794
Echinococcus granulosus lamin dm0 0.011 0.0147 0.0145
Leishmania major cathepsin L-like protease 0.1481 0.2276 0.6442
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.0015
Trichomonas vaginalis ran, putative 0.0026 0.0017 0.0042
Giardia lamblia Cathepsin B precursor 0.0425 0.0637 0.179
Loa Loa (eye worm) hypothetical protein 0.008 0.0101 0.0099
Trypanosoma brucei metacaspase MCA3 0.0019 0.0006 0.0016
Schistosoma mansoni tyrosine kinase 0.052 0.0785 0.0785
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0088 0.0377
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6453 1 1
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0241 0.0352 0.035
Plasmodium falciparum serine repeat antigen 1 0.0425 0.0637 0.2794
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0088 0.0086
Echinococcus granulosus cathepsin l cysteine peptidase 0.1481 0.2276 0.2275
Brugia malayi Nuclear hormone receptor E75 0.0071 0.0088 0.0088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0108 0.0144 0.0144
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Brugia malayi TAR-binding protein 0.0216 0.0313 0.0313
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0043 0.0044 0.0715
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.008 0.0101 0.0099
Loa Loa (eye worm) hypothetical protein 0.0022 0.001 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.0057 0.0065 0.0065
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0151 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0425 0.0637 0.18
Schistosoma mansoni neuroligin 3 (S09 family) 0.0106 0.0142 0.0142
Echinococcus granulosus thioredoxin glutathione reductase 0.0055 0.0062 0.006
Giardia lamblia Kinase, CMGC MAPK 0.0037 0.0034 0.008
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0425 0.0637 0.2794
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0425 0.0637 0.0637
Loa Loa (eye worm) hypothetical protein 0.0428 0.0641 0.064
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0006 0.0004
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0247 0.036 0.0358
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Schistosoma mansoni caspase-3 (C14 family) 0.007 0.0085 0.0085
Brugia malayi latrophilin 2 splice variant baaae 0.0369 0.055 0.055
Toxoplasma gondii LsmAD domain-containing protein 0.0019 0.0006 0.0016
Echinococcus granulosus methyl CpG binding domain protein 2 0.0059 0.0069 0.0067
Echinococcus multilocularis histone acetyltransferase MYST2 0.0093 0.0121 0.0119
Brugia malayi nuclear receptor NHR-67 0.0071 0.0088 0.0088
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Toxoplasma gondii Hsp90 domain-containing protein 0.0016 0.0002 0.0005
Echinococcus multilocularis transcription factor Dp 1 0.0027 0.0018 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0106 0.0296
Schistosoma mansoni myst-related protein 0.0021 0.0009 0.0009
Trypanosoma cruzi ISWI complex protein 0.0053 0.0059 0.0057
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0853 0.1302 0.1302
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0124 0.0169 0.3094
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0321 0.0476 0.0474
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Echinococcus multilocularis isocitrate dehydrogenase 0.0052 0.0058 0.0056
Onchocerca volvulus 0.1481 0.2276 1
Brugia malayi jmjC domain containing protein 0.0039 0.0038 0.0038
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0006 0.0006
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.0147 0.0145
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.0015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0037 0.0034 0.0032
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0209 0.0301 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Entamoeba histolytica cysteine proteinase, putative 0.1481 0.2276 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0679 0.1031 0.103
Brugia malayi Nuclear hormone receptor-like 1 0.008 0.0101 0.0101
Echinococcus granulosus caspase 2 0.0019 0.0006 0.0004
Echinococcus granulosus chromobox protein 1 0.0057 0.0066 0.0064
Echinococcus multilocularis tar DNA binding protein 0.0216 0.0313 0.0311
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0428 0.0641 0.064
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Schistosoma mansoni cathepsin F (C01 family) 0.1053 0.1612 0.1612
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0151 0.0212 0.021
Schistosoma mansoni polycystin 1-related 0.0061 0.0072 0.0072
Leishmania major cathepsin L-like protease 0.1481 0.2276 0.6442
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0425 0.0637 0.2794
Loa Loa (eye worm) hypothetical protein 0.011 0.0147 0.0145
Brugia malayi beta-NAC-like protein 0.0083 0.0106 0.0106
Schistosoma mansoni smad1 5 8 and 0.0019 0.0006 0.0006
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0006 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1053 0.1612 0.456
Echinococcus granulosus acetylcholinesterase 0.063 0.0956 0.0954
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0006 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0056 0.0054
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0017 0.0015
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0049 0.0052 0.0977
Schistosoma mansoni thyroid hormone receptor 0.0151 0.0212 0.0212
Echinococcus granulosus Nuclear hormone receptor HR96 0.0071 0.0088 0.0086
Plasmodium vivax glutathione reductase, putative 0.0054 0.0061 0.026
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0425 0.0637 0.179
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0108 0.0144 0.0142
Echinococcus multilocularis phd:f box containing protein 0.0039 0.0038 0.0036
Schistosoma mansoni rab6-interacting 0.0061 0.0072 0.0072
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0095 0.0125 0.0123
Echinococcus granulosus carboxylesterase 5A 0.063 0.0956 0.0954
Trichomonas vaginalis CMGC family protein kinase 0.0037 0.0034 0.0092
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0093 0.0121 0.0119
Toxoplasma gondii cathepsin CPL 0.1481 0.2276 0.6443
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Echinococcus multilocularis polycomb protein SCMH1 0.0082 0.0103 0.0102
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0088 0.0086
Loa Loa (eye worm) ctsf protein 0.1481 0.2276 0.2275
Plasmodium vivax JmjC domain containing protein 0.0039 0.0038 0.0158
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.003 0.0125
Brugia malayi Pre-SET motif family protein 0.032 0.0475 0.0475
Echinococcus granulosus mitogen activated protein kinase 0.0037 0.0034 0.0032
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0031 0.0025 0.0067
Giardia lamblia Cathepsin B precursor 0.0425 0.0637 0.179
Echinococcus multilocularis inositol monophosphatase 1 0.0056 0.0064 0.0063
Loa Loa (eye worm) CHromoDomain protein family member 0.0023 0.0012 0.0011
Loa Loa (eye worm) hypothetical protein 0.0108 0.0144 0.0142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0144 0.0144
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6453 1 1
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0038 0.0158
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0043 0.0044 0.0184
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0679 0.1031 0.103
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0072 0.007
Echinococcus granulosus lamin 0.011 0.0147 0.0145
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0058 0.0056
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0151 0.0212 0.0212
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0046 0.0049 0.0047
Brugia malayi Cathepsin L-like precursor 0.0428 0.0641 0.0641
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0039 0.0038 0.0107
Schistosoma mansoni hypothetical protein 0.0372 0.0554 0.0554
Plasmodium falciparum serine repeat antigen 8 0.0425 0.0637 0.2794
Giardia lamblia Cathepsin B precursor 0.0425 0.0637 0.179
Toxoplasma gondii aldehyde dehydrogenase 0.0247 0.036 0.1018
Giardia lamblia Cysteine protease 0.0425 0.0637 0.179
Loa Loa (eye worm) ICD-1 protein 0.0083 0.0106 0.0105
Loa Loa (eye worm) hypothetical protein 0.0053 0.0059 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Plasmodium vivax vivapain-1 0.0853 0.1302 0.5715
Schistosoma mansoni transcription factor btf3 0.0083 0.0106 0.0106
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0141 0.0196 0.0554
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Echinococcus multilocularis SAM and MBT domain containing protein 0.0082 0.0103 0.0102
Loa Loa (eye worm) isocitrate dehydrogenase 0.0052 0.0058 0.0056
Brugia malayi Heterochromatin protein 1 0.0057 0.0066 0.0066
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0059 0.0069 0.0067
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 0.0853
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0041 0.004 0.0113
Trypanosoma cruzi metacaspase, putative 0.0019 0.0006 0.0004
Brugia malayi chromobox protein homolog 3 0.0032 0.0027 0.0027
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0058 0.0066 0.0066
Plasmodium vivax vivapain-3 0.0853 0.1302 0.5715
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0017 0.0047
Brugia malayi Cathepsin L-like cysteine proteinase 0.1053 0.1612 0.1612
Mycobacterium tuberculosis Probable oxidoreductase 0.0137 0.019 0.3501
Toxoplasma gondii heat shock protein 90, putative 0.0039 0.0038 0.0107
Brugia malayi Papain family cysteine protease containing protein 0.0853 0.1302 0.1302
Echinococcus granulosus neuropeptide receptor A26 0.1032 0.1579 0.1578
Plasmodium falciparum LCCL domain-containing protein 0.0061 0.0072 0.0309
Trichomonas vaginalis ap endonuclease, putative 0.0043 0.0044 0.0118
Brugia malayi RNA recognition motif domain containing protein 0.0216 0.0313 0.0313
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0052 0.0058 0.0056
Echinococcus granulosus jumonji domain containing protein 0.0064 0.0076 0.0074
Onchocerca volvulus 0.011 0.0147 0.0638
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0059 0.0057
Echinococcus multilocularis jumonji domain containing 1A 0.0039 0.0038 0.0036
Brugia malayi MH2 domain containing protein 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0071 0.0088 0.0377
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0321 0.0476 0.1347
Onchocerca volvulus 0.0082 0.0103 0.0447
Onchocerca volvulus Huntingtin homolog 0.0242 0.0352 0.1539
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0021 0.0053
Schistosoma mansoni ran 0.0026 0.0017 0.0017
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0019 0.0006 0.0006
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0058 0.0164
Brugia malayi Carboxylesterase family protein 0.0106 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Echinococcus granulosus GPCR family 2 0.0171 0.0242 0.024
Echinococcus granulosus lipoxygenase domain containing protein 0.0061 0.0072 0.007
Trypanosoma cruzi ISWI complex protein 0.0053 0.0059 0.0057
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0151 0.0212 0.021
Echinococcus multilocularis mitogen activated protein kinase 0.0037 0.0034 0.0032
Schistosoma mansoni cathepsin F (C01 family) 0.1481 0.2276 0.2276
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0247 0.036 0.0358
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0004
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Echinococcus granulosus cysteine protease 0.0853 0.1302 0.13
Schistosoma mansoni tyrosine kinase 0.0313 0.0463 0.0463
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0048 0.0202
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0043 0.0044 0.0107
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0039 0.0038 0.0107
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0151 0.0212 0.021
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0054 0.0061 0.1045
Plasmodium falciparum glutathione reductase 0.0019 0.0006 0.0018
Brugia malayi Inositol-1 0.0056 0.0064 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Echinococcus multilocularis JmjC domain containing protein 4 0.0039 0.0038 0.0036
Trypanosoma cruzi cysteine peptidase, putative 0.0428 0.0641 0.064
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0142 0.0142
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0043 0.0044 0.0042
Echinococcus multilocularis heat shock protein 90 0.0031 0.0025 0.0024
Trypanosoma cruzi major cysteine proteinase, putative 0.0425 0.0637 0.0636
Toxoplasma gondii heat shock protein 75, putative 0.0016 0.0002 0.0005
Plasmodium falciparum serine repeat antigen 7 0.0425 0.0637 0.2794
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Echinococcus granulosus Smad4 0.0019 0.0006 0.0004
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Loa Loa (eye worm) hypothetical protein 0.6453 1 1
Treponema pallidum heat shock protein 90 0.0031 0.0025 0.0305
Loa Loa (eye worm) jmjC domain-containing protein 0.0039 0.0038 0.0036
Leishmania major GTP-binding protein, putative 0.0026 0.0017 0.0042
Brugia malayi Carboxylesterase family protein 0.063 0.0956 0.0956
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0043 0.0044 0.198
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0428 0.0641 0.0641
Toxoplasma gondii cathepsin CPC2 0.0425 0.0637 0.1804
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Brugia malayi isocitrate dehydrogenase 0.0052 0.0058 0.0058
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 1
Loa Loa (eye worm) hypothetical protein 0.0369 0.055 0.0549
Loa Loa (eye worm) hypothetical protein 0.054 0.0816 0.0814
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0014 0.0035
Brugia malayi jmjC domain containing protein 0.0161 0.0226 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Schistosoma mansoni retinoic acid receptor RXR 0.0151 0.0212 0.0212
Schistosoma mansoni cpg binding protein 0.0133 0.0184 0.0184
Leishmania major metacaspase, putative 0.0019 0.0006 0.0011
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.003 0.003
Brugia malayi hypothetical protein 0.0061 0.0072 0.0072
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0088 0.0088
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0019 0.0006 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0082 0.0103 0.0447
Schistosoma mansoni jumonji domain containing protein 0.0211 0.0304 0.0304
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0212 0.0212
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0043 0.0044 0.0118
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Brugia malayi Cathepsin L-like precursor 0.1053 0.1612 0.1612
Schistosoma mansoni hypothetical protein 0.0227 0.033 0.033
Brugia malayi nuclear receptor RXR 0.008 0.0101 0.0101
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0425 0.0637 0.2794
Schistosoma mansoni myelin transcription factor 1 myt1 0.0093 0.0121 0.0121
Echinococcus multilocularis mitogen activated protein kinase 3 0.0037 0.0034 0.0032
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0313 0.0463 0.0461
Echinococcus multilocularis lysine specific demethylase 6a 0.0039 0.0038 0.0036
Plasmodium falciparum basic transcription factor 3b, putative 0.0083 0.0106 0.0459
Onchocerca volvulus 0.1481 0.2276 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0425 0.0637 0.2794
Loa Loa (eye worm) cysteine protease 0.1481 0.2276 0.2275
Schistosoma mansoni tar DNA-binding protein 0.0216 0.0313 0.0313
Plasmodium vivax SET domain protein, putative 0.0048 0.0052 0.0219
Echinococcus granulosus endonuclease exonuclease phosphatase 0.033 0.0489 0.0488
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Echinococcus multilocularis caspase 8 0.0019 0.0006 0.0004
Entamoeba histolytica hypothetical protein 0.0057 0.0065 0.0278
Mycobacterium ulcerans aldehyde dehydrogenase 0.0247 0.036 0.672
Entamoeba histolytica hypothetical protein 0.0057 0.0065 0.0278
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0052 0.0058 0.0164
Schistosoma mansoni bromodomain containing protein 0.0226 0.0329 0.0329
Brugia malayi conserved hypotetical protein 0.0071 0.0088 0.0088
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0046 0.0049 0.0206
Mycobacterium tuberculosis Probable dehydrogenase 0.0124 0.0169 0.3094
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0066 0.0182
Brugia malayi hypothetical protein 0.038 0.0566 0.0566
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0425 0.0637 0.18
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Brugia malayi Probable ClpP-like protease 0.0141 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Loa Loa (eye worm) endoplasmin 0.0039 0.0038 0.0036
Echinococcus granulosus inositol monophosphatase 1 0.0056 0.0064 0.0063
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0034 0.003 0.0125
Trypanosoma cruzi polo-like protein kinase, putative 0.0093 0.0122 0.012
Onchocerca volvulus 0.1053 0.1612 0.7079
Entamoeba histolytica cysteine proteinase, putative 0.0853 0.1302 0.5715
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.6453 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0151 0.0212 0.021
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0039 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Loa Loa (eye worm) mbt repeat family protein 0.0082 0.0103 0.0102
Trypanosoma cruzi metacaspase, putative 0.0019 0.0006 0.0004
Entamoeba histolytica hypothetical protein 0.0057 0.0065 0.0278
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0427 0.064 0.2808
Schistosoma mansoni tar DNA-binding protein 0.0216 0.0313 0.0313
Brugia malayi cathepsin Z-like cysteine proteinase 0.0425 0.0637 0.0637
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0035 0.0031 0.0127
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0041 0.004 0.0167
Brugia malayi Latrophilin receptor protein 2 0.0171 0.0242 0.0242
Trypanosoma brucei heat shock protein 84, putative 0.0016 0.0002 0.0005
Echinococcus granulosus histone acetyltransferase MYST2 0.0093 0.0121 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Echinococcus multilocularis musashi 0.011 0.0147 0.0145
Brugia malayi hypothetical protein 0.0057 0.0065 0.0065
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Schistosoma mansoni tyrosine kinase 0.0526 0.0794 0.0794
Plasmodium falciparum heat shock protein 90 0.0039 0.0038 0.0158
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0052 0.0058 0.0995
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.008 0.0101 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0151 0.0212 0.021
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0425 0.0637 0.2794
Mycobacterium tuberculosis Conserved hypothetical protein 0.0358 0.0532 1
Brugia malayi cathepsin L precursor 0.0425 0.0637 0.0637
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0171 0.0242 0.024
Loa Loa (eye worm) acetylcholinesterase 1 0.063 0.0956 0.0954
Brugia malayi Papain family cysteine protease containing protein 0.0425 0.0637 0.0637
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0425 0.0637 0.0636
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0031 0.0087
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Leishmania major trypanothione reductase 0.0054 0.0061 0.0168
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0425 0.0637 0.2794
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0151 0.0212 0.021
Echinococcus granulosus cathepsin b 0.6453 1 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0011 0.0026
Trichomonas vaginalis mercuric reductase, putative 0.0019 0.0006 0.0012
Schistosoma mansoni peptidase Clp (S14 family) 0.0141 0.0196 0.0196
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0256 0.0375 0.0375
Brugia malayi Bromodomain containing protein 0.0267 0.0392 0.0392
Echinococcus granulosus ecdysone induced protein 78C 0.0151 0.0212 0.021
Plasmodium vivax serine-repeat antigen (SERA) 0.0425 0.0637 0.2794
Schistosoma mansoni tar DNA-binding protein 0.0216 0.0313 0.0313
Trichomonas vaginalis heat shock protein, putative 0.0031 0.0025 0.0067
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0108 0.0144 0.0142
Giardia lamblia Cathepsin B precursor 0.229 0.3533 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0012 0.0029
Echinococcus multilocularis heat shock protein 90 0.0039 0.0038 0.0036
Loa Loa (eye worm) fibroinase 0.1481 0.2276 0.2275
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0019 0.0006 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Schistosoma mansoni bromodomain containing protein 0.0022 0.001 0.001
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0093 0.0122 0.012
Loa Loa (eye worm) heat shock protein 90 0.0039 0.0038 0.0036
Leishmania major importin beta-1 subunit, putative 0.0028 0.0021 0.0053
Brugia malayi MH2 domain containing protein 0.0019 0.0006 0.0006
Echinococcus multilocularis peregrin 0.0054 0.0061 0.0059
Schistosoma mansoni endoplasmin 0.0039 0.0038 0.0038
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0056 0.0064 0.0182
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0037 0.0034 0.0032
Entamoeba histolytica cysteine proteinase 2 0.0853 0.1302 0.5715
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Echinococcus granulosus intermediate filament protein 0.011 0.0147 0.0145
Entamoeba histolytica hypothetical protein 0.0057 0.0065 0.0278
Brugia malayi nuclear receptor NHR-88 0.0151 0.0212 0.0212
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0107 0.0144 0.0144
Brugia malayi jmjC domain containing protein 0.0039 0.0038 0.0038
Brugia malayi hypothetical protein 0.0242 0.0352 0.0352
Echinococcus multilocularis cathepsin L cysteine protease 0.1481 0.2276 0.2275
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Loa Loa (eye worm) glutaminase 2 0.0232 0.0337 0.0336
Brugia malayi Hsp90 protein 0.0016 0.0002 0.0002
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0031 0.0087
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0049 0.0133
Entamoeba histolytica hypothetical protein 0.0028 0.0021 0.0083
Echinococcus multilocularis caspase 3 0.0051 0.0056 0.0054
Schistosoma mansoni ap endonuclease 0.0043 0.0044 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Schistosoma mansoni coup transcription factor 0.0151 0.0212 0.0212
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Plasmodium falciparum ataxin-2 like protein, putative 0.0019 0.0006 0.0017
Schistosoma mansoni smad1 5 8 and 0.0019 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Plasmodium vivax unspecified product 0.0425 0.0637 0.2794
Loa Loa (eye worm) hypothetical protein 0.0136 0.0189 0.0187
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0026 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Brugia malayi PHD-finger family protein 0.0046 0.0048 0.0048
Schistosoma mansoni tyrosine kinase 0.052 0.0785 0.0785
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0082 0.0103 0.0103
Mycobacterium ulcerans hypothetical protein 0.0358 0.0532 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0151 0.0212 0.0212
Echinococcus multilocularis GPCR, family 2 0.0171 0.0242 0.024
Schistosoma mansoni heat shock protein 0.0016 0.0002 0.0002
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.032 0.0475 0.0473
Schistosoma mansoni hypothetical protein 0.0171 0.0242 0.0242
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Brugia malayi nuclear receptor NHR-88 0.0071 0.0088 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Loa Loa (eye worm) TAR-binding protein 0.0216 0.0313 0.0311
Trypanosoma cruzi cysteine peptidase, putative 0.0853 0.1302 0.13
Brugia malayi heat shock protein 90 0.0039 0.0038 0.0038
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0038 0.0107
Brugia malayi nuclear hormone receptor family member nhr-6 0.0071 0.0088 0.0088
Schistosoma mansoni cathepsin C 0.0425 0.0637 0.0637
Onchocerca volvulus 0.1481 0.2276 1
Brugia malayi mbt repeat family protein 0.0082 0.0103 0.0103
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0019 0.0006 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0106 0.0296
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Plasmodium vivax multidomain scavenger receptor, putative 0.0061 0.0072 0.0309
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0006 0.0004
Onchocerca volvulus Cathepsin L homolog 0.1481 0.2276 1
Plasmodium falciparum serine repeat antigen 5 0.0425 0.0637 0.2794
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0124 0.0169 0.3094
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Trypanosoma brucei PAB1-binding protein , putative 0.0019 0.0006 0.0016
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1481 0.2276 1
Schistosoma mansoni nuclear receptor nhr-48 0.0071 0.0088 0.0088
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0006 0.0006
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1481 0.2276 0.2275
Giardia lamblia Cysteine protease 0.0425 0.0637 0.179
Entamoeba histolytica cysteine protease, putative 0.1481 0.2276 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0053 0.0059 0.0057
Onchocerca volvulus Cathepsin L homolog 0.1481 0.2276 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0017 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0425 0.0637 0.18
Schistosoma mansoni tyrosine kinase 0.0526 0.0794 0.0794
Plasmodium vivax importin-beta 2, putative 0.0035 0.0031 0.0128
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0006 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0043 0.0044 0.0042
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0137 0.019 0.5983
Brugia malayi Bromodomain containing protein 0.0054 0.0061 0.0061
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0093 0.0122 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0425 0.0637 0.18
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Plasmodium falciparum phd finger protein, putative 0.0046 0.0048 0.0202
Plasmodium vivax vivapain-2 0.1481 0.2276 1
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0046 0.0049 0.0133
Brugia malayi Papain family cysteine protease containing protein 0.0425 0.0637 0.0637
Schistosoma mansoni tar DNA-binding protein 0.0216 0.0313 0.0313
Entamoeba histolytica heat shock protein 90, putative 0.0039 0.0038 0.0158
Onchocerca volvulus 0.1481 0.2276 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0016 0.0014
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0108 0.0144 0.0142
Echinococcus multilocularis dnaJ subfamily B 0.1305 0.2004 0.2003
Entamoeba histolytica cysteine proteinase, putative 0.0853 0.1302 0.5715
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Schistosoma mansoni cpg binding protein 0.012 0.0163 0.0163
Schistosoma mansoni hypothetical protein 0.0171 0.0242 0.0242
Echinococcus granulosus acetylcholinesterase 0.063 0.0956 0.0954
Schistosoma mansoni lipoxygenase 0.0157 0.0221 0.0221
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Brugia malayi Carboxylesterase family protein 0.063 0.0956 0.0956
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.008 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0006 0.0004
Plasmodium falciparum JmjC domain-containing protein, putative 0.0039 0.0038 0.0158
Schistosoma mansoni protein phosphatase 2C 0.0039 0.0038 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0161 0.0226 0.0226
Echinococcus multilocularis cpg binding protein 0.0133 0.0184 0.0182
Echinococcus multilocularis microtubule associated protein 2 0.4056 0.6277 0.6276
Brugia malayi Nuclear hormone receptor-like 1 0.0151 0.0212 0.0212
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0037 0.0034 0.0092
Plasmodium falciparum serine repeat antigen 4 0.0425 0.0637 0.2794
Entamoeba histolytica hypothetical protein 0.0021 0.0009 0.0032
Echinococcus multilocularis para nitrobenzyl esterase 0.0106 0.0142 0.014
Echinococcus granulosus zinc finger protein 0.0075 0.0093 0.0091
Trichomonas vaginalis endoplasmin, putative 0.0024 0.0014 0.0035
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0085 0.0109 0.0107
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0052 0.0058 0.0159
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0093 0.0122 0.012
Brugia malayi exodeoxyribonuclease III family protein 0.0043 0.0044 0.0044
Trypanosoma cruzi transcription factor btf3, putative 0.0083 0.0106 0.0105
Leishmania major hypothetical protein, conserved 0.0039 0.0038 0.0102
Plasmodium vivax metacaspase 1, putative 0.0019 0.0006 0.0017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.008 0.0101 0.0101
Echinococcus granulosus lysine specific demethylase 6a 0.0039 0.0038 0.0036
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0006 0.0004
Brugia malayi Cathepsin L-like precursor 0.1053 0.1612 0.1612
Trypanosoma cruzi cysteine protease, putative 0.0853 0.1302 0.13
Plasmodium vivax heat shock protein 86, putative 0.0039 0.0038 0.0158
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Echinococcus multilocularis heat shock protein 0.0039 0.0038 0.0036
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0151 0.0212 0.0212
Schistosoma mansoni cathepsin B (C01 family) 0.0425 0.0637 0.0637
Schistosoma mansoni tyrosine kinase 0.0313 0.0463 0.0463
Giardia lamblia Cathepsin B precursor 0.0425 0.0637 0.179
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0046 0.0049 0.0049
Echinococcus granulosus caspase 8 0.0019 0.0006 0.0004
Loa Loa (eye worm) thioredoxin reductase 0.0054 0.0061 0.0059
Brugia malayi cathepsin Z-like cysteine proteinase 0.0425 0.0637 0.0637
Loa Loa (eye worm) hypothetical protein 0.1481 0.2276 0.2275
Echinococcus granulosus lysine specific demethylase 5A 0.0161 0.0226 0.0224
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Schistosoma mansoni methyl-cpg binding protein mbd 0.0059 0.0069 0.0069
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0093 0.0121 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Echinococcus granulosus mitogen activated protein kinase 3 0.0037 0.0034 0.0032
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0216 0.0313 0.0311
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0037 0.0035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0425 0.0637 0.2794
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0017 0.0015
Loa Loa (eye worm) hypothetical protein 0.0061 0.0072 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0425 0.0637 0.18
Schistosoma mansoni tyrosine kinase 0.0979 0.1497 0.1497
Plasmodium falciparum serine repeat antigen 2 0.0425 0.0637 0.2794
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0031 0.0025 0.0024
Schistosoma mansoni caspase-7 (C14 family) 0.007 0.0085 0.0085
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.229 0.3533 0.3533
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0212 0.0212
Echinococcus multilocularis survival motor neuron protein 1 0.038 0.0566 0.0565
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0425 0.0637 0.0636
Echinococcus multilocularis PHD finger protein rhinoceros 0.0046 0.0048 0.0046
Schistosoma mansoni lamin 0.011 0.0147 0.0147
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0038 0.009
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1481 0.2276 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0151 0.0212 0.021
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0209 0.0301 0.5605
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0092 0.012 0.2174
Loa Loa (eye worm) hypothetical protein 0.0093 0.0121 0.0119
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0136 0.0189 0.0822
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Echinococcus granulosus geminin 0.1237 0.1898 0.1896
Schistosoma mansoni tyrosine kinase 0.052 0.0785 0.0785
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0056 0.0064 0.0063
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0019 0.0006 0.0018
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.6453 1 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0026 0.0024
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0031 0.0029
Giardia lamblia Hypothetical protein 0.0425 0.0637 0.179
Brugia malayi Carboxylesterase family protein 0.0106 0.0142 0.0142
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Plasmodium falciparum metacaspase-like protein 0.0019 0.0006 0.0017
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0428 0.0641 0.064
Leishmania major cathepsin L-like protease 0.1481 0.2276 0.6442
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0106 0.0142 0.014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0171 0.0242 0.024
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0151 0.0212 0.0212
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0071 0.0088 0.0086
Echinococcus granulosus heat shock protein 0.0039 0.0038 0.0036
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0049 0.0052 0.0222
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1481 0.2276 0.2275
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Giardia lamblia Cysteine protease 0.0425 0.0637 0.179
Echinococcus granulosus survival motor neuron protein 1 0.038 0.0566 0.0565
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0039 0.0038 0.0036
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0034 0.003 0.003
Mycobacterium ulcerans heat shock protein 90 0.0031 0.0025 0.0368
Loa Loa (eye worm) nuclear hormone receptor 0.0071 0.0088 0.0086
Toxoplasma gondii NAC domain-containing protein 0.0083 0.0106 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Trypanosoma brucei cysteine peptidase C (CPC) 0.229 0.3533 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0071 0.0088 0.0086
Schistosoma mansoni nuclear hormone receptor 0.0151 0.0212 0.0212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0853 0.1302 0.3685
Echinococcus multilocularis epidermal growth factor receptor 0.0979 0.1497 0.1496
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0141 0.0196 0.2993
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0043 0.0044 0.0042
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0046 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0037 0.0034 0.0092
Plasmodium falciparum metacaspase 1 0.0019 0.0006 0.0017
Trypanosoma cruzi Heat shock protein 83, putative 0.0039 0.0038 0.0036
Echinococcus multilocularis transcription factor btf3 0.0083 0.0106 0.0105
Brugia malayi Bromodomain containing protein 0.0133 0.0183 0.0183
Onchocerca volvulus 0.0071 0.0088 0.0377
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0057 0.0065 0.0063
Trypanosoma cruzi trypanothione reductase, putative 0.0019 0.0006 0.0004
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0095 0.0125 0.0123
Leishmania major cathepsin L-like protease 0.1481 0.2276 0.6442
Echinococcus granulosus smad 0.0019 0.0006 0.0004
Trypanosoma cruzi cysteine proteinase, putative 0.0853 0.1302 0.13
Brugia malayi hypothetical protein 0.008 0.0101 0.0101
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0124 0.0169 0.3094
Echinococcus granulosus caspase 0.007 0.0085 0.0083
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0425 0.0637 0.179
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0037 0.0034 0.0032
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.063 0.0956 0.0956
Schistosoma mansoni myst-related protein 0.0021 0.0009 0.0009
Echinococcus multilocularis thioredoxin glutathione reductase 0.0055 0.0062 0.006
Brugia malayi CHD4 protein 0.0023 0.0012 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Giardia lamblia PHD finger protein 15 0.0046 0.0048 0.0118
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0171 0.0242 0.0242
Onchocerca volvulus Huntingtin homolog 0.0242 0.0352 0.1539
Mycobacterium ulcerans carboxylesterase, LipT 0.0106 0.0142 0.2588
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0151 0.0212 0.021
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0006 0.0011
Brugia malayi photoreceptor-specific nuclear receptor 0.0151 0.0212 0.0212
Loa Loa (eye worm) TK/INSR protein kinase 0.0313 0.0463 0.0461
Loa Loa (eye worm) PHD-finger family protein 0.0072 0.0088 0.0086
Schistosoma mansoni lipoxygenase 0.0268 0.0393 0.0393
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0241 0.0352 0.035
Plasmodium vivax thioredoxin reductase, putative 0.0054 0.0061 0.026
Echinococcus granulosus peregrin 0.0054 0.0061 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0034 0.009
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0037 0.0035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0151 0.0212 0.0212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Echinococcus granulosus chromobox protein 1 0.0057 0.0066 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Brugia malayi hypothetical protein 0.0061 0.0072 0.0072
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0017 0.003
Schistosoma mansoni importin beta-1 0.0035 0.0031 0.0031
Onchocerca volvulus 0.1481 0.2276 1
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Onchocerca volvulus 0.1481 0.2276 1
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Loa Loa (eye worm) hypothetical protein 0.0155 0.0217 0.0216
Schistosoma mansoni ran 0.0026 0.0017 0.0017
Echinococcus multilocularis zinc finger protein 0.0075 0.0093 0.0091
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Brugia malayi F/Y-rich N-terminus family protein 0.006 0.007 0.007
Trypanosoma brucei heat shock protein, putative 0.0039 0.0038 0.0107
Loa Loa (eye worm) hypothetical protein 0.0171 0.0242 0.024
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0526 0.0794 0.0792
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0006 0.0016
Trichomonas vaginalis spcc417.12 protein, putative 0.0106 0.0142 0.0398
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0151 0.0212 0.021
Loa Loa (eye worm) intermediate filament protein 0.011 0.0147 0.0145
Giardia lamblia Cysteine protease 0.0425 0.0637 0.179
Schistosoma mansoni cathepsin s 0.0428 0.0641 0.0641
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0151 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.008 0.0101 0.0099
Echinococcus granulosus thyroid hormone receptor alpha 0.0071 0.0088 0.0086
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0038 0.0036
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0122 0.034
Loa Loa (eye worm) hypothetical protein 0.0107 0.0144 0.0142
Echinococcus multilocularis caspase 0.007 0.0085 0.0083
Brugia malayi Pre-SET motif family protein 0.0048 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.0425 0.0637 0.0636
Schistosoma mansoni hypothetical protein 0.1305 0.2004 0.2004
Schistosoma mansoni hypothetical protein 0.0061 0.0072 0.0072
Giardia lamblia Cathepsin L precursor 0.0425 0.0637 0.179
Brugia malayi Calcitonin receptor-like protein seb-1 0.054 0.0816 0.0816
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0031 0.0087
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0151 0.0212 0.0923
Brugia malayi serine/threonine-protein kinase plk-2 0.0093 0.0122 0.0122
Trichomonas vaginalis heat shock protein, putative 0.0024 0.0014 0.0035
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1481 0.2276 0.6442
Brugia malayi cathepsin F-like cysteine proteinase 0.0425 0.0637 0.0637
Schistosoma mansoni lamin 0.011 0.0147 0.0147
Onchocerca volvulus 0.012 0.0163 0.0709
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0006 0.0004
Trichomonas vaginalis helicase, putative 0.0027 0.0019 0.0049
Mycobacterium tuberculosis Probable reductase 0.0124 0.0169 0.3094
Echinococcus granulosus snurportin 1 0.0372 0.0554 0.0552
Plasmodium falciparum serine repeat antigen 3 0.0425 0.0637 0.2794
Loa Loa (eye worm) carboxylesterase 0.0106 0.0142 0.014
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0031 0.0025 0.0368
Echinococcus granulosus histone lysine methyltransferase setb 0.0107 0.0144 0.0142
Brugia malayi hypothetical protein 0.008 0.0101 0.0101
Trypanosoma cruzi heat shock protein 90, putative 0.0023 0.0013 0.0011
Schistosoma mansoni hypothetical protein 0.0077 0.0097 0.0097
Loa Loa (eye worm) carboxylesterase 0.0106 0.0142 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0027 0.0071
Echinococcus granulosus nuclear receptor nhr 48 0.0071 0.0088 0.0086
Brugia malayi Carboxylesterase family protein 0.0106 0.0142 0.0142
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0038 0.0036
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0038 0.0036
Entamoeba histolytica serine/threonine protein kinase, putative 0.0093 0.0122 0.0528
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Onchocerca volvulus 0.0106 0.0142 0.0617
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0012
Echinococcus multilocularis epidermal growth factor receptor 0.0526 0.0794 0.0792
Onchocerca volvulus 0.0106 0.0142 0.0617
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Echinococcus multilocularis neuroligin 0.0106 0.0142 0.014
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0425 0.0637 0.0637
Plasmodium falciparum glutathione reductase 0.0054 0.0061 0.026
Schistosoma mansoni chromobox protein 0.0057 0.0066 0.0066
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0425 0.0637 0.0637
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0006 0.0017
Brugia malayi Cathepsin L-like precursor 0.1481 0.2276 0.2276
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.007 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.0141 0.0196 0.0195
Brugia malayi Papain family cysteine protease containing protein 0.0425 0.0637 0.0637
Schistosoma mansoni phd/f-box containing protein 0.0039 0.0038 0.0038
Trypanosoma cruzi cysteine peptidase, putative 0.2278 0.3516 0.3514
Schistosoma mansoni jumonji/arid domain-containing protein 0.0161 0.0226 0.0226
Giardia lamblia Cathepsin B precursor 0.0425 0.0637 0.179
Schistosoma mansoni cpg binding protein 0.0133 0.0184 0.0184
Leishmania major hypothetical protein, conserved 0.0053 0.0059 0.0163
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0425 0.0637 0.18
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0071 0.0088 0.0086
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.0147 0.0147
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0425 0.0637 0.2794
Toxoplasma gondii PHD-finger domain-containing protein 0.0046 0.0048 0.0135
Echinococcus multilocularis chromobox protein 1 0.0057 0.0066 0.0064
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0006 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Trypanosoma cruzi PAB1-binding protein , putative 0.0019 0.0006 0.0004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0141 0.0196 0.6187
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0071 0.0088 0.0088
Onchocerca volvulus 0.0061 0.0072 0.0309
Brugia malayi cathepsin F-like cysteine proteinase 0.0428 0.0641 0.0641
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0019 0.0006 0.0017
Trichomonas vaginalis inositol monophosphatase, putative 0.0056 0.0064 0.0177
Mycobacterium tuberculosis Carboxylesterase LipT 0.0106 0.0142 0.2588
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0425 0.0637 0.2794
Echinococcus granulosus heat shock protein 90 0.0031 0.0025 0.0024
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Loa Loa (eye worm) CXXC zinc finger family protein 0.012 0.0163 0.0161
Brugia malayi hypothetical protein 0.0106 0.0142 0.0142
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0038 0.0036
Toxoplasma gondii isocitrate dehydrogenase 0.0052 0.0058 0.0164
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.1851 0.2851 0.285
Loa Loa (eye worm) cathepsin B 0.229 0.3533 0.3532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0425 0.0637 0.18
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0853 0.1302 0.13
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Loa Loa (eye worm) heterochromatin protein 1 0.0057 0.0066 0.0064
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0006 0.0006
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0425 0.0637 0.2794
Echinococcus granulosus heat shock protein 90 0.0039 0.0038 0.0036
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0425 0.0637 0.179
Loa Loa (eye worm) hypothetical protein 0.0035 0.0031 0.0029
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0006 0.0016
Entamoeba histolytica cysteine protease, putative 0.0425 0.0637 0.2794
Giardia lamblia Fructose-bisphosphate aldolase 0.0427 0.064 0.1799
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0034 0.009
Brugia malayi Importin beta-1 subunit 0.0035 0.0031 0.0031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0151 0.0212 0.0212
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0427 0.064 0.1809
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0004
Giardia lamblia Cathepsin L-like protease 0.0425 0.0637 0.179
Loa Loa (eye worm) hypothetical protein 0.0071 0.0088 0.0086
Echinococcus multilocularis expressed protein 0.0041 0.004 0.0038
Brugia malayi tailless protein 0.0071 0.0088 0.0088
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0071 0.0088 0.0086
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0125 0.0171 0.0169
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0039 0.0038 0.0107
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Echinococcus granulosus epidermal growth factor receptor 0.0979 0.1497 0.1496
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0019 0.0006 0.0004
Echinococcus granulosus tar DNA binding protein 0.0216 0.0313 0.0311
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0046 0.0049 0.0047
Trichomonas vaginalis chromobox protein, putative 0.0057 0.0066 0.0182
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0088 0.0088
Giardia lamblia Cathepsin B precursor 0.229 0.3533 1
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0037 0.0034 0.0097
Echinococcus granulosus jumonji domain containing 1A 0.0039 0.0038 0.0036
Echinococcus granulosus SAM and MBT domain containing protein 0.0082 0.0103 0.0102
Echinococcus granulosus caspase 3 0.0051 0.0056 0.0054
Loa Loa (eye worm) doublecortin family protein 0.0061 0.0072 0.007
Brugia malayi jmjC domain containing protein 0.0039 0.0038 0.0038
Giardia lamblia Hypothetical protein 0.0425 0.0637 0.179
Leishmania major heat shock protein 83-1 0.0039 0.0038 0.0102
Plasmodium vivax endoplasmin, putative 0.0039 0.0038 0.0158
Echinococcus granulosus cathepsin L cysteine protease 0.0853 0.1302 0.13
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0151 0.0212 0.0212
Treponema pallidum exodeoxyribonuclease (exoA) 0.0043 0.0044 0.0593
Brugia malayi Isocitrate dehydrogenase 0.0052 0.0058 0.0058
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0124 0.0169 0.3094
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0023 0.0012 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0019 0.0049
Loa Loa (eye worm) hypothetical protein 0.0151 0.0212 0.021
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0034 0.003 0.0086
Schistosoma mansoni chromobox protein 0.0057 0.0066 0.0066
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0106 0.0142 0.0142
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0072 0.007
Echinococcus multilocularis acetylcholinesterase 0.063 0.0956 0.0954
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.229 0.3533 0.3532
Onchocerca volvulus Cell death protein 3 homolog 0.0019 0.0006 0.0017
Echinococcus multilocularis cathepsin L 0.0853 0.1302 0.13
Onchocerca volvulus 0.0106 0.0142 0.0617
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0088 0.0086
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0043 0.0044 0.0042
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0056 0.0064 0.0177
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0019 0.0006 0.0012
Schistosoma mansoni inositol monophosphatase 0.0056 0.0064 0.0064
Schistosoma mansoni gliotactin 0.0106 0.0142 0.0142
Schistosoma mansoni hypothetical protein 0.0034 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.063 0.0956 0.0954
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.2278 0.3516 0.9951
Plasmodium falciparum zinc finger protein, putative 0.0021 0.0009 0.0032
Schistosoma mansoni heat shock protein 0.0039 0.0038 0.0038
Echinococcus granulosus cathepsin L 0.0853 0.1302 0.13
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0425 0.0637 0.18
Onchocerca volvulus Cathepsin L homolog 0.0425 0.0637 0.2794
Schistosoma mansoni Smad4 0.0019 0.0006 0.0006
Onchocerca volvulus 0.0025 0.0016 0.0062
Trypanosoma brucei heat shock protein 90, putative 0.0039 0.0038 0.0107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0151 0.0212 0.0212
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0214 0.0309 0.0308
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0425 0.0637 0.18
Loa Loa (eye worm) hypothetical protein 0.0245 0.0358 0.0356
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0095 0.0125 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1481 0.2276 0.6442
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0268 0.0393 0.0391
Loa Loa (eye worm) hypothetical protein 0.0106 0.0142 0.014
Plasmodium vivax basic transcription factor 3b, putative 0.0083 0.0106 0.0459
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.005 0.0055 0.1084
Loa Loa (eye worm) PHD-finger family protein 0.0046 0.0048 0.0046
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0141 0.0196 0.0853
Leishmania major cathepsin L-like protease 0.2278 0.3516 0.9951
Echinococcus granulosus cathepsin L cysteine proteinase 0.1481 0.2276 0.2275
Brugia malayi Steroid receptor seven-up type 2 0.0151 0.0212 0.0212
Onchocerca volvulus 0.1481 0.2276 1
Plasmodium vivax hypothetical protein, conserved 0.0022 0.0011 0.0042
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0209 0.0301 0.5605
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0425 0.0637 0.0637
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0141 0.0196 0.0554
Schistosoma mansoni ap endonuclease 0.0043 0.0044 0.0044
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0425 0.0637 0.2794
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0151 0.0212 0.0212
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0214 0.0309 0.0308
Schistosoma mansoni hypothetical protein 0.0053 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.063 0.0956 0.0954
Echinococcus multilocularis geminin 0.1237 0.1898 0.1896
Schistosoma mansoni inositol monophosphatase 0.0056 0.0064 0.0064
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0106 0.0142 0.2588
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0057 0.0065 0.0063
Brugia malayi jmjC domain containing protein 0.0241 0.0352 0.0352
Entamoeba histolytica cysteine proteinase, putative 0.1053 0.1612 0.7079
Trichomonas vaginalis chromobox protein, putative 0.0035 0.0031 0.0082
Loa Loa (eye worm) jmjC domain-containing protein 0.0161 0.0226 0.0224
Schistosoma mansoni aldehyde dehydrogenase 0.0247 0.036 0.036
Brugia malayi MAP kinase sur-1 0.0037 0.0034 0.0034
Schistosoma mansoni survival motor neuron protein 0.0077 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0638 0.0967 0.0966
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0425 0.0637 0.18
Echinococcus granulosus transcription factor btf3 0.0083 0.0106 0.0105
Brugia malayi Protein kinase domain containing protein 0.0313 0.0463 0.0463
Trypanosoma cruzi cruzipain precursor, putative 0.2278 0.3516 0.3514
Loa Loa (eye worm) hypothetical protein 0.0046 0.0048 0.0046
Echinococcus multilocularis FTZ F1 alpha 0.0151 0.0212 0.021
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0071 0.0088 0.0377
Toxoplasma gondii heat shock protein HSP90 0.0039 0.0038 0.0107
Trypanosoma cruzi cysteine peptidase, putative 0.2278 0.3516 0.3514
Entamoeba histolytica cysteine protease, putative 0.0853 0.1302 0.5715
Schistosoma mansoni hypothetical protein 0.0504 0.076 0.076
Toxoplasma gondii isocitrate dehydrogenase 0.0052 0.0058 0.0164
Echinococcus granulosus cathepsin L 0.0425 0.0637 0.0636
Echinococcus multilocularis lipoxygenase domain containing protein 0.0061 0.0072 0.007
Trichomonas vaginalis glutathione reductase, putative 0.0019 0.0006 0.0012
Echinococcus multilocularis insulin receptor 0.0313 0.0463 0.0461

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 1.149 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Based Secondary Assay to Identify Inhibitors of Resistant C. albicans Growth in the Presence of Fluconazole. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1979, AID2007] ChEMBL. No reference
EC50 (functional) > 150 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Based Secondary Assay to Measure Toxicity of Compounds Not in the Presence of Fluconazole. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1979, AID2007, AID434946] ChEMBL. No reference
EC50 (functional) > 150 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Hsp90. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1979, AID2007, AID434938] ChEMBL. No reference
EC50 (functional) > 180 uM PUBCHEM_BIOASSAY: Luminescence Cell-Based Secondary Assay to Identify Inhibitors of Calcineurin. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1979, AID2007] ChEMBL. No reference
Potency (functional) 5.2213 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 6.5131 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.7157 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.