Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0029 | 0 | 0.5 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.1142 | 1 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trichomonas vaginalis | Sialidase-1 precursor, putative | 0.1123 | 0.9831 | 1 |
Onchocerca volvulus | 4.1 G protein, putative homolog | 0.0029 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0127 | 0.0886 | 0.0886 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0029 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0698 | 0.6016 | 0.6119 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.1142 | 1 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 0.9998 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1123 | 0.9831 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 0.9998 |
Giardia lamblia | Protein tyrosine phosphatase | 0.0029 | 0 | 0.5 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 0.9998 |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0029 | 0 | 0.5 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0029 | 0 | 0.5 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0127 | 0.0886 | 0.0886 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma brucei | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0127 | 0.0886 | 0.0886 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.1142 | 1 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.1142 | 1 | 1 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0029 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 0.9998 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Onchocerca volvulus | 0.0029 | 0 | 0.5 | |
Trypanosoma cruzi | trans-sialidase, putative | 0.0307 | 0.2501 | 1 |
Trypanosoma brucei | trans-sialidase | 0.0307 | 0.2501 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.