Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | heat shock protein HSP90 | 0.0032 | 0.149 | 0.2911 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0032 | 0.149 | 0.6916 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0017 | 0.0422 | 0.0435 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0013 | 0.0174 | 0.0179 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1785 | 0.1785 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0013 | 0.0174 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0017 | 0.0422 | 0.0422 |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0084 | 0.512 | 0.5279 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.9512 | 0.9512 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3722 | 0.3722 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0017 | 0.0422 | 0.0422 |
Echinococcus granulosus | phd:f box containing protein | 0.0017 | 0.0422 | 0.0435 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.149 | 0.149 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0429 | 0.0442 |
Echinococcus multilocularis | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0063 | 0.3618 | 0.373 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0017 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2954 | 0.2954 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0154 | 1 | 1 |
Plasmodium falciparum | endoplasmin, putative | 0.002 | 0.0628 | 0.1227 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0422 | 0.0422 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.2418 | 0.4723 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.1036 | 0.2024 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.149 | 0.6163 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3722 | 0.3722 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.2954 | 0.2954 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0026 | 0.1036 | 0.2024 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0032 | 0.149 | 0.149 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0026 | 0.1036 | 0.2024 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.1036 | 0.1036 |
Trichomonas vaginalis | endoplasmin, putative | 0.002 | 0.0628 | 0.2597 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0017 | 0.0422 | 0.0435 |
Schistosoma mansoni | phd/f-box containing protein | 0.0017 | 0.0422 | 0.0422 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | phd:f box containing protein | 0.0017 | 0.0422 | 0.0422 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0084 | 0.512 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0084 | 0.512 | 0.512 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0084 | 0.512 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.2418 | 0.4723 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Plasmodium vivax | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0017 | 0.0422 | 0.0824 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | hypothetical protein, conserved | 0.0017 | 0.0422 | 0.0824 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0042 | 0.2155 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.9512 | 0.9512 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0429 | 0.0429 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0017 | 0.0422 | 0.0422 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.2418 | 0.2493 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.2418 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.9512 | 0.9512 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0084 | 0.512 | 1 |
Trypanosoma cruzi | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0013 | 0.0174 | 0.0174 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.149 | 0.149 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0084 | 0.512 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0017 | 0.0422 | 0.0824 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0017 | 0.0422 | 0.0824 |
Schistosoma mansoni | heat shock protein | 0.0013 | 0.0174 | 0.0174 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0084 | 0.512 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0026 | 0.1036 | 0.4808 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0084 | 0.512 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Echinococcus multilocularis | heat shock protein | 0.0032 | 0.149 | 0.149 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3722 | 0.3837 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0017 | 0.0422 | 0.0435 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Loa Loa (eye worm) | endoplasmin | 0.0032 | 0.149 | 0.149 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.149 | 0.149 |
Plasmodium vivax | JmjC domain containing protein | 0.0017 | 0.0422 | 0.0824 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.1036 | 0.1068 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.149 | 0.6916 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0084 | 0.512 | 0.512 |
Echinococcus granulosus | heat shock protein | 0.0032 | 0.149 | 0.1537 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0429 | 0.0429 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Plasmodium vivax | heat shock protein, putative | 0.0013 | 0.0174 | 0.0339 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0013 | 0.0174 | 0.0339 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0429 | 0.0442 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0429 | 0.0429 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Brugia malayi | Hsp90 protein | 0.0013 | 0.0174 | 0.0174 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0063 | 0.3618 | 0.373 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.2418 | 0.4723 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0013 | 0.0174 | 0.0339 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0154 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Plasmodium falciparum | heat shock protein 90 | 0.0032 | 0.149 | 0.2911 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0013 | 0.0174 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0422 | 0.0422 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3722 | 0.3722 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0429 | 0.0429 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | jumonji domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Schistosoma mansoni | protein phosphatase 2C | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Echinococcus granulosus | heat shock protein 90 | 0.0032 | 0.149 | 0.1537 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.015 | 0.9699 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.2954 | 0.2954 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1785 | 0.1785 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0013 | 0.0174 | 0.0719 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0429 | 0.0429 |
Trichomonas vaginalis | heat shock protein, putative | 0.002 | 0.0628 | 0.2597 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0013 | 0.0174 | 0.0174 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0084 | 0.512 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.2418 | 1 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0032 | 0.149 | 0.2911 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.2954 | 0.2954 |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.1036 | 0.1068 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0084 | 0.512 | 0.512 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0017 | 0.0422 | 0.0824 |
Loa Loa (eye worm) | acetyltransferase | 0.0154 | 1 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.1036 | 0.1068 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.9512 | 0.9512 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0042 | 0.2155 | 0.4209 |
Plasmodium vivax | heat shock protein 86, putative | 0.0032 | 0.149 | 0.2911 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.3618 | 0.3618 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.149 | 0.2911 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0429 | 0.0429 |
Brugia malayi | Endoplasmin precursor | 0.0032 | 0.149 | 0.149 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.1036 | 0.2024 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3722 | 0.3722 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0084 | 0.512 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0429 | 0.0429 |
Toxoplasma gondii | methionine aminopeptidase | 0.0084 | 0.512 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0429 | 0.0442 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0019 | 0.0576 | 0.1126 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0026 | 0.1036 | 0.2024 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.9512 | 0.9512 |
Giardia lamblia | Grp94/Hsp90 | 0.0026 | 0.1036 | 0.4808 |
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.3618 | 0.3618 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.1036 | 0.4285 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0032 | 0.149 | 0.6916 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.1036 | 0.1036 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.149 | 0.2911 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3722 | 0.3722 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0084 | 0.512 | 1 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0013 | 0.0174 | 0.0806 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0063 | 0.3618 | 0.3618 |
Trypanosoma brucei | heat shock protein, putative | 0.0032 | 0.149 | 0.2911 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0422 | 0.0435 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3722 | 0.3722 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.149 | 0.149 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0084 | 0.512 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0026 | 0.1036 | 0.2024 |
Plasmodium vivax | endoplasmin, putative | 0.0032 | 0.149 | 0.2911 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.9512 | 0.9807 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Brugia malayi | jmjC domain containing protein | 0.0017 | 0.0422 | 0.0422 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0017 | 0.0422 | 0.0422 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0042 | 0.2155 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1785 | 0.1785 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.