Detailed information for compound 930011

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 203.279 | Formula: C10H21NO3
  • H donors: 2 H acceptors: 3 LogP: 0.26 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC[N+](CC(CC(=O)[O-])O)(CC)CC
  • InChi: 1S/C10H21NO3/c1-4-11(5-2,6-3)8-9(12)7-10(13)14/h9,12H,4-8H2,1-3H3
  • InChiKey: GJFCXKXSMQLCRN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0087 0.0212
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0124 0.0092
Loa Loa (eye worm) RNA binding protein 0.0059 0.0727 0.0724
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0132
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.038 0.038
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.3336 0.838
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni alpha-1 adrenergic receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) fatty acid elongation protein 3 0.067 1 1
Schistosoma mansoni tar DNA-binding protein 0.0059 0.0727 0.1823
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Loa Loa (eye worm) carboxylesterase 0.0046 0.0533 0.053
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni elongation of fatty acids protein 1 0.0135 0.1886 0.4741
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.038 0.0817
Plasmodium falciparum long chain fatty acid elongation enzyme, putative 0.067 1 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0046 0.0533 1
Trypanosoma cruzi GMP reductase 0.0105 0.1434 0.1405
Schistosoma mansoni amine GPCR 0.0032 0.0311 0.0775
Brugia malayi ATP synthase alpha chain, mitochondrial precursor, putative 0.0013 0.0036 0.0033
Echinococcus multilocularis mitochondrial F1F0 ATP synthase subunit epsilon 0.0017 0.0096 0.0161
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0124 0.0121
Brugia malayi G-protein coupled receptor 0.0032 0.0311 0.0308
Schistosoma mansoni ATP synthase alpha subunit mitochondrial 0.0013 0.0036 0.0083
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0055 0.0058
Schistosoma mansoni biogenic amine receptor 0.0032 0.0311 0.0775
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Loa Loa (eye worm) cysteine protease 0.0017 0.0087 0.0084
Loa Loa (eye worm) hypothetical protein 0.0017 0.0087 0.0084
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0047 0.054 0.0537
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0087 0.0087
Leishmania major cathepsin L-like protease 0.0064 0.0802 0.0802
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus granulosus fmrfamide receptor 0.0032 0.0311 0.0775
Brugia malayi hypothetical protein 0.0231 0.3336 0.3334
Echinococcus multilocularis elongation of very long chain fatty acids 0.0135 0.1886 0.4702
Schistosoma mansoni hypothetical protein 0.0047 0.0547 0.137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0032 0.0311 0.1636
Brugia malayi Dopamine receptor 0.0032 0.0311 0.0308
Toxoplasma gondii fatty acid elongase 0.0135 0.1886 0.186
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0124 0.0124
Onchocerca volvulus 0.0032 0.0311 0.1636
Echinococcus granulosus mitochondrial F1F0 ATP synthase subunit epsilon 0.0017 0.0096 0.0234
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0311 0.0706
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0105 0.1434 0.1405
Echinococcus granulosus g protein coupled receptor 0.0032 0.0311 0.0775
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0105 0.1434 0.3296
Schistosoma mansoni neuropeptide receptor 0.0032 0.0311 0.0775
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0533 0.1333
Schistosoma mansoni tar DNA-binding protein 0.0059 0.0727 0.1823
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0124 0.0092
Leishmania major cathepsin L-like protease 0.0064 0.0802 0.0802
Echinococcus granulosus caspase 3 0.0053 0.0631 0.1582
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi Carboxylesterase family protein 0.0046 0.0533 0.053
Schistosoma mansoni histamine h1 receptor 0.0032 0.0311 0.0775
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0087 0.0447
Trypanosoma cruzi fatty acid elongase, putative 0.067 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.038 0.0349
Loa Loa (eye worm) acetylcholinesterase 1 0.0273 0.3975 0.3973
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0087 0.0055
Echinococcus granulosus peptide allatostatin:somatostatin 0.0032 0.0311 0.0775
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0156 0.0153
Echinococcus granulosus elongation of very long chain fatty acids 0.0135 0.1886 0.4741
Echinococcus multilocularis elongation of very long chain fatty acids 0.0135 0.1886 0.4702
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0032 0.0311 0.0775
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Brugia malayi larval opioid receptor 0.0032 0.0311 0.0308
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0311 0.0706
Loa Loa (eye worm) hypothetical protein 0.0231 0.3336 0.3334
Echinococcus granulosus ATP synthase subunit alpha mitochondrial 0.0013 0.0036 0.0083
Loa Loa (eye worm) fatty acid elongation protein 3 0.0135 0.1886 0.1884
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Trypanosoma brucei Fatty acid elongase 0.067 1 1
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0032 0.0311 0.0308
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0055 0.0052
Echinococcus multilocularis caspase 2 0.0019 0.0124 0.0232
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0311 0.0775
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0087 0.0084
Plasmodium vivax vivapain-2 0.0017 0.0087 0.0051
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0323 0.0682
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.038 0.7117
Schistosoma mansoni acetylcholinesterase 0.0046 0.0533 0.1333
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni inositol monophosphatase 0.0036 0.038 0.0949
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis sex peptide receptor 0.0032 0.0311 0.0706
Trypanosoma brucei metacaspase MCA2 0.0019 0.0124 0.0124
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0046 0.0537 0.0534
Brugia malayi G-protein coupled receptor 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0017 0.0087 0.0447
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0311 0.0706
Echinococcus granulosus 7tm_1 domain containing protein 0.0032 0.0311 0.0775
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0311 0.0775
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0087 0.0447
Leishmania major metacaspase, putative 0.0019 0.0124 0.0124
Loa Loa (eye worm) fatty acid elongation protein 3 0.0135 0.1886 0.1884
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0533 0.1177
Onchocerca volvulus 0.0017 0.0087 0.0447
Mycobacterium tuberculosis Carboxylesterase LipT 0.0046 0.0533 0.1177
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus BC026374 protein S09 family 0.0046 0.0533 0.1333
Echinococcus multilocularis G protein coupled receptor 139 0.0032 0.0311 0.0706
Mycobacterium ulcerans carboxylesterase, LipT 0.0046 0.0533 0.1177
Brugia malayi TAR-binding protein 0.0059 0.0727 0.0724
Brugia malayi putative neuropeptide receptor 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Brugia malayi Dopamine receptor protein 2 0.0032 0.0311 0.0308
Brugia malayi ATP synthase epsilon chain, mitochondrial 0.0017 0.0096 0.0093
Echinococcus multilocularis acetylcholinesterase 0.0273 0.3975 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0032 0.0311 0.0775
Toxoplasma gondii IMP dehydrogenas 0.0105 0.1434 0.1405
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0087 0.0212
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis neuroligin 0.0046 0.0533 0.1268
Trypanosoma cruzi fatty acid elongase, putative 0.067 1 1
Echinococcus granulosus orexin receptor type 2 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi Carboxylesterase family protein 0.0273 0.3975 0.3973
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0311 0.0706
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis g-protein coupled receptor 0.0032 0.0311 0.0706
Trypanosoma brucei metacaspase 0.0019 0.0124 0.0124
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0021 0.0156 0.0291
Loa Loa (eye worm) GNS1/SUR4 family protein 0.067 1 1
Plasmodium vivax metacaspase 1, putative 0.0019 0.0124 0.0089
Brugia malayi Carboxylesterase family protein 0.0046 0.0533 0.053
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0311 0.0706
Loa Loa (eye worm) CYP4Cod1 0.0021 0.0156 0.0153
Leishmania major fatty acid elongase, putative 0.067 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0032 0.0311 0.0706
Onchocerca volvulus Neuropeptide F receptor homolog 0.0032 0.0311 0.1636
Echinococcus multilocularis muscleblind protein 1 0.0146 0.2046 0.5107
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Schistosoma mansoni biogenic amine receptor 0.0032 0.0311 0.0775
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0032 0.0311 0.0775
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0047 0.054 0.0537
Trypanosoma cruzi metacaspase, putative 0.0019 0.0124 0.0092
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Schistosoma mansoni opsin-like receptor 0.0032 0.0311 0.0775
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0156 0.0124
Onchocerca volvulus 0.0135 0.1886 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0105 0.1434 0.1405
Echinococcus granulosus G protein coupled receptor 139 0.0032 0.0311 0.0775
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0087 0.0447
Echinococcus multilocularis neuropeptide receptor A26 0.0032 0.0311 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Echinococcus multilocularis serotonin receptor 0.0032 0.0311 0.0706
Brugia malayi G protein-coupled receptor 0.0032 0.0311 0.0308
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0032 0.0311 0.0308
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0032 0.0311 0.0706
Plasmodium falciparum metacaspase-like protein 0.0019 0.0124 0.0089
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Echinococcus multilocularis somatostatin receptor 0.0032 0.0311 0.0706
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.038 0.038
Echinococcus multilocularis neuropeptide s receptor 0.0032 0.0311 0.0706
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0032 0.0311 0.0775
Leishmania major fatty acid elongase, putative 0.067 1 1
Echinococcus granulosus somatostatin receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0046 0.0533 0.2812
Echinococcus granulosus neuropeptide Y receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Leishmania major cytochrome p450-like protein 0.0013 0.0033 0.0033
Brugia malayi GMP reductase 0.0047 0.054 0.0537
Mycobacterium leprae PROBABLE ATP SYNTHASE ALPHA CHAIN ATPA 0.0013 0.0036 0.0024
Brugia malayi Calcitonin receptor-like protein seb-1 0.0046 0.0537 0.0534
Onchocerca volvulus 0.0032 0.0311 0.1636
Plasmodium vivax vivapain-2 0.0017 0.0087 0.0051
Echinococcus granulosus hypothetical protein 0.0032 0.0311 0.0775
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0046 0.0533 0.1177
Echinococcus multilocularis GPCR, family 2 0.0015 0.0055 0.0058
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni amine GPCR 0.0032 0.0311 0.0775
Trypanosoma cruzi GMP reductase 0.0105 0.1434 0.1405
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Schistosoma mansoni amine GPCR 0.0032 0.0311 0.0775
Schistosoma mansoni neuropeptide receptor 0.0032 0.0311 0.0775
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Onchocerca volvulus 0.0046 0.0533 0.2812
Trypanosoma brucei GMP reductase 0.0105 0.1434 0.1434
Trypanosoma brucei Long chain fatty acyl elongase 0.0135 0.1886 0.1886
Echinococcus granulosus neuropeptide s receptor 0.0032 0.0311 0.0775
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.038 0.2462
Echinococcus multilocularis dro:myosuppressin receptor 0.0032 0.0311 0.0706
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0802 0.0772
Echinococcus multilocularis caspase 8 0.0019 0.0124 0.0232
Schistosoma mansoni hypothetical protein 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0087 0.0138
Schistosoma mansoni elongation of fatty acids protein 1 0.0135 0.1886 0.4741
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0121
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0135 0.1886 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0087 0.2232
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0105 0.1434 0.3296
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0046 0.0533 0.2812
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni caspase-3 (C14 family) 0.0072 0.0923 0.2316
Trypanosoma brucei Fatty acid elongase 0.0135 0.1886 0.1886
Leishmania major cathepsin L-like protease 0.0017 0.0087 0.0087
Trypanosoma brucei elongation of very long chain fatty acids protein, putative 0.0135 0.1886 0.1886
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0105 0.1434 0.1403
Echinococcus multilocularis acetylcholinesterase 0.0273 0.3975 1
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0059 0.0726 0.4952
Echinococcus granulosus g protein coupled receptor 0.0032 0.0311 0.0775
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0105 0.1434 0.1403
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0032 0.0311 0.0706
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Echinococcus granulosus GPCR family 2 0.0015 0.0055 0.0132
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0087 0.0138
Echinococcus multilocularis fmrfamide receptor 0.0032 0.0311 0.0706
Brugia malayi cytochrome P450 0.0013 0.0033 0.003
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi Cytochrome P450 family protein 0.0021 0.0156 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Leishmania major inosine-5-monophosphate dehydrogenase 0.0105 0.1434 0.1434
Onchocerca volvulus 0.0032 0.0311 0.1636
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0105 0.1434 0.3553
Schistosoma mansoni cytochrome P450 0.0013 0.0033 0.0074
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus carboxylesterase 5A 0.0273 0.3975 1
Brugia malayi Cell death protein 3 precursor 0.0019 0.0124 0.0121
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0273 0.3975 1
Brugia malayi GNS1/SUR4 family protein 0.0135 0.1886 0.1884
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Loa Loa (eye worm) TYRA-2 protein 0.0032 0.0311 0.0308
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0311 0.0706
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0718 0.0688
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0032 0.0311 0.0775
Trypanosoma brucei cytochrome P450, putative 0.0021 0.0156 0.0156
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Echinococcus multilocularis BC026374 protein (S09 family) 0.0046 0.0533 0.1268
Schistosoma mansoni amine GPCR 0.0032 0.0311 0.0775
Plasmodium falciparum long chain polyunsaturated fatty acid elongation enzyme, putative 0.0135 0.1886 0.1857
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0046 0.0533 0.2812
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0124 0.0305
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Brugia malayi Carboxylesterase family protein 0.0046 0.0533 0.053
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0132
Schistosoma mansoni elongation of fatty acids protein 1 0.0135 0.1886 0.4741
Brugia malayi Tachykinin-like peptides receptor 99D 0.0032 0.0311 0.0308
Brugia malayi AKH receptor 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0047 0.0547 0.289
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Echinococcus granulosus 7TM GPCR rhodopsin 0.0032 0.0311 0.0775
Echinococcus multilocularis muscleblind protein 0.0146 0.2046 0.5107
Trypanosoma cruzi fatty acid elongase, putative 0.067 1 1
Onchocerca volvulus 0.0017 0.0087 0.0447
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0013 0.0033 0.0033
Schistosoma mansoni neuroligin 3 (S09 family) 0.0046 0.0533 0.1333
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Echinococcus multilocularis orexin receptor type 2 0.0032 0.0311 0.0706
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0124 0.0092
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0311 0.0706
Echinococcus multilocularis allatostatin A receptor 0.0032 0.0311 0.0706
Brugia malayi putative neuropeptide receptor NPR1 0.0032 0.0311 0.0308
Brugia malayi RNA recognition motif domain containing protein 0.0059 0.0727 0.0724
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0533 0.1333
Brugia malayi Carboxylesterase family protein 0.0046 0.0533 0.053
Onchocerca volvulus Elongation of very long chain fatty acids protein homolog 0.0135 0.1886 1
Brugia malayi Serotonin receptor 0.0032 0.0311 0.0308
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0802 0.0772
Mycobacterium ulcerans short chain dehydrogenase 0.0293 0.4282 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0293 0.4282 1
Echinococcus multilocularis cysteine protease 0.0017 0.0087 0.0138
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0032 0.0311 0.0706
Echinococcus granulosus g-protein coupled receptor 0.0032 0.0311 0.0775
Schistosoma mansoni growth hormone secretagogue receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis serotonin receptor 0.0032 0.0311 0.0706
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0124 0.0305
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0311 0.0706
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0311 0.0308
Brugia malayi fatty acid elongation protein 3 0.0135 0.1886 0.1884
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0105 0.1434 1
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni fatty acid acyl transferase-related 0.0135 0.1886 0.4741
Brugia malayi Melatonin receptor type 1A 0.0032 0.0311 0.0308
Brugia malayi follicle stimulating hormone receptor 0.0032 0.0311 0.0308
Echinococcus multilocularis para nitrobenzyl esterase 0.0046 0.0533 0.1268
Brugia malayi fatty acid elongation protein 3 0.0135 0.1886 0.1884
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0311 0.0775
Brugia malayi Dopamine receptor protein 1 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Loa Loa (eye worm) IMP dehydrogenase 1 0.0105 0.1434 0.1431
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Echinococcus multilocularis carboxylesterase 5A 0.0273 0.3975 1
Onchocerca volvulus Putative GMP reductase 0.0047 0.054 0.2851
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0105 0.1434 0.3601
Echinococcus granulosus caspase 8 0.0019 0.0124 0.0305
Brugia malayi Cytochrome P450 family protein 0.0021 0.0156 0.0153
Loa Loa (eye worm) fibroinase 0.0017 0.0087 0.0084
Echinococcus granulosus sex peptide receptor 0.0032 0.0311 0.0775
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0311 0.0775
Schistosoma mansoni hypothetical protein 0.0013 0.0033 0.0074
Plasmodium falciparum fatty acid elongation protein, GNS1/SUR4 family, putative 0.067 1 1
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0132
Brugia malayi hypothetical protein 0.0046 0.0533 0.053
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0105 0.1434 0.1431
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Leishmania major cytochrome p450-like protein 0.0021 0.0156 0.0156
Loa Loa (eye worm) GNS1/SUR4 family protein 0.0135 0.1886 0.1884
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni tar DNA-binding protein 0.0059 0.0727 0.1823
Loa Loa (eye worm) TAR-binding protein 0.0059 0.0727 0.0724
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma cruzi metacaspase, putative 0.0019 0.0124 0.0092
Leishmania major long chain polyunsaturated fatty acid elongation enzyme-like protein 0.0135 0.1886 0.1886
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0802 0.0772
Trypanosoma cruzi metacaspase, putative 0.0019 0.0124 0.0092
Onchocerca volvulus 0.0017 0.0087 0.0447
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0087 0.0051
Loa Loa (eye worm) ATP synthase subunit epsilon 0.0017 0.0096 0.0093
Loa Loa (eye worm) inositol-1 0.0036 0.038 0.0377
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0323 0.207
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0032 0.0311 0.0308
Trypanosoma cruzi fatty acid elongase, putative 0.067 1 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0055 0.0132
Schistosoma mansoni adenoreceptor 0.0032 0.0311 0.0775
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0032 0.0311 0.0775
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Brugia malayi G protein-coupled receptor F59B2.13 0.0032 0.0311 0.0308
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0055 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi Serotonin receptor 0.0032 0.0311 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0032 0.0311 0.0775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Leishmania major cathepsin L-like protease 0.0017 0.0087 0.0087
Echinococcus granulosus caspase 0.0072 0.0923 0.2316
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0032 0.0311 0.0308
Brugia malayi latrophilin 2 splice variant baaae 0.0032 0.0314 0.0311
Echinococcus granulosus caspase 2 0.0019 0.0124 0.0305
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Leishmania major cathepsin L-like protease 0.0064 0.0802 0.0802
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0547 0.0544
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0311 0.0775
Echinococcus multilocularis neuropeptide FF receptor 2 0.0032 0.0311 0.0706
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0072 0.0923 0.2316
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0105 0.1434 0.1405
Mycobacterium tuberculosis Probable ATP synthase beta chain AtpD 0.0013 0.0036 0.0008
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.038 0.7117
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Loa Loa (eye worm) neuropeptide F receptor 0.0032 0.0311 0.0308
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0032 0.0311 0.0775
Leishmania major cathepsin L-like protease 0.0017 0.0087 0.0087
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0032 0.0311 0.0706
Echinococcus multilocularis tar DNA binding protein 0.0059 0.0727 0.1762
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Loa Loa (eye worm) melatonin receptor type 1A 0.0032 0.0311 0.0308
Echinococcus granulosus neuroligin 0.0046 0.0533 0.1333
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0032 0.0311 0.0706
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Schistosoma mansoni opsin-like receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) carboxylesterase 0.0046 0.0533 0.053
Echinococcus granulosus neuropeptide receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni elongation of fatty acids protein 1 0.0135 0.1886 0.4741
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni biogenic amine (5HT) receptor 0.0032 0.0311 0.0775
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0032 0.0311 0.0775
Echinococcus granulosus tar DNA binding protein 0.0059 0.0727 0.1823
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0032 0.0311 0.0775
Onchocerca volvulus ATP synthase subunit alpha, mitochondrial homolog 0.0013 0.0036 0.0175
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Echinococcus granulosus biogenic amine 5HT receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0032 0.0311 0.1636
Plasmodium falciparum metacaspase 1 0.0019 0.0124 0.0089
Schistosoma mansoni caspase-7 (C14 family) 0.0072 0.0923 0.2316
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Loa Loa (eye worm) ctsf protein 0.0017 0.0087 0.0084
Toxoplasma gondii atp synthase F1, epsilon subunit, putative 0.0017 0.0096 0.0064
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Onchocerca volvulus 0.0046 0.0533 0.2812
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus rhodopsin orphan GPCR 0.0032 0.0311 0.0775
Echinococcus multilocularis neuropeptides capa receptor 0.0032 0.0311 0.0706
Entamoeba histolytica cysteine protease, putative 0.0017 0.0087 0.2232
Schistosoma mansoni hypothetical protein 0.0032 0.0314 0.0783
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0311 0.0775
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0087 0.1588
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis ATP synthase subunit alpha, mitochondrial 0.0013 0.0036 0.0008
Brugia malayi neuropeptide F receptor 0.0032 0.0311 0.0308
Schistosoma mansoni biogenic amine receptor 0.0032 0.0311 0.0775
Mycobacterium leprae PROBABLE ATP SYNTHASE BETA CHAIN ATPD 0.0013 0.0036 0.0024
Schistosoma mansoni gliotactin 0.0046 0.0533 0.1333
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0124 0.0092
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni inositol monophosphatase 0.0036 0.038 0.0949
Echinococcus granulosus dro:myosuppressin receptor 0.0032 0.0311 0.0775
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.038 0.0349
Plasmodium vivax ATP synthase epsilon chain, mitochondrial , putative 0.0017 0.0096 0.006
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.3336 0.8392
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Mycobacterium tuberculosis Probable ATP synthase alpha chain AtpA 0.0013 0.0036 0.0008
Trypanosoma brucei metacaspase MCA3 0.0019 0.0124 0.0124
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0087 0.0138
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.038 0.0949
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0124 0.0089
Plasmodium vivax long chain polyunsaturated fatty acid elongation enzyme, putative 0.0135 0.1886 0.1857
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni neuropeptide f receptor 76f 0.0032 0.0311 0.0775
Toxoplasma gondii GNS1/SUR4 family protein 0.067 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Brugia malayi RNA binding protein 0.0059 0.0727 0.0724
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0032 0.0311 0.0706
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0072 0.0923 0.2258
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0032 0.0311 0.1636
Schistosoma mansoni neuropeptide receptor 0.0032 0.0311 0.0775
Echinococcus granulosus muscleblind protein 0.0146 0.2046 0.5143
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Schistosoma mansoni hypothetical protein 0.0032 0.0311 0.0775
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0105 0.1434 0.3296
Brugia malayi sulfakinin receptor protein 0.0032 0.0311 0.0308
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Brugia malayi GNS1/SUR4 family protein 0.067 1 1
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Leishmania major guanosine monophosphate reductase 0.0105 0.1434 0.1434
Onchocerca volvulus 0.0032 0.0311 0.1636
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0087 0.0138
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0032 0.0311 0.0706
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0087 0.0212
Brugia malayi fatty acid elongation protein 3 0.0135 0.1886 0.1884
Loa Loa (eye worm) cytochrome P450 family protein 0.0031 0.0302 0.0299
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0059 0.0727 0.0724
Onchocerca volvulus 0.0032 0.0311 0.1636
Loa Loa (eye worm) hypothetical protein 0.0273 0.3975 0.3973
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Loa Loa (eye worm) G-protein coupled receptor 0.0032 0.0311 0.0308
Trypanosoma cruzi metacaspase, putative 0.0019 0.0124 0.0092
Schistosoma mansoni hypothetical protein 0.0017 0.0096 0.0234
Onchocerca volvulus 0.0032 0.0311 0.1636
Loa Loa (eye worm) carboxylesterase 0.0273 0.3975 0.3973
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0087 0.0051
Loa Loa (eye worm) hypothetical protein 0.0019 0.0124 0.0121
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0017 0.0087 0.0447
Onchocerca volvulus 0.0032 0.0311 0.1636
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.038 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0087 0.0051
Onchocerca volvulus 0.0017 0.0087 0.0447
Loa Loa (eye worm) cytochrome P450 0.0013 0.0033 0.003
Brugia malayi Hypothetical 34.1 kDa protein C40H1.4 in chromosome III 0.0135 0.1886 0.1884
Leishmania major cytochrome p450-like protein 0.0013 0.0033 0.0033
Echinococcus granulosus neuropeptide receptor A26 0.0032 0.0311 0.0775
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Mycobacterium ulcerans F0F1 ATP synthase subunit alpha 0.0013 0.0036 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0055 0.0052
Echinococcus granulosus elongation of very long chain fatty acids 0.0135 0.1886 0.4741
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0032 0.0311 0.0706
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0311 0.0706
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0124 0.0092
Echinococcus granulosus cytochrome P450 2K1 0.0013 0.0033 0.0074
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0055 0.0058
Schistosoma mansoni tar DNA-binding protein 0.0059 0.0727 0.1823
Echinococcus multilocularis neuropeptide Y receptor 0.0032 0.0311 0.0706
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Echinococcus multilocularis G-protein coupled receptor, putative 0.0032 0.0311 0.0706
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0032 0.0311 0.0706
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0032 0.0311 0.1636
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0032 0.0311 0.1636
Echinococcus multilocularis neuropeptide receptor 0.0032 0.0311 0.0706
Onchocerca volvulus Elongation of very long chain fatty acids protein 5 homolog 0.0135 0.1886 1
Schistosoma mansoni myosin xvIII 0.0032 0.0311 0.0775
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi GnHR receptor homolog 0.0032 0.0311 0.0308
Schistosoma mansoni neuropeptide receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.038 0.0881
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Onchocerca volvulus 0.0032 0.0311 0.1636
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0013 0.0033 0.0033
Brugia malayi Inositol-1 0.0036 0.038 0.0377
Trypanosoma brucei Fatty acid elongase 0.0135 0.1886 0.1886
Echinococcus granulosus alpha 1A adrenergic receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis g protein coupled receptor 0.0032 0.0311 0.0706
Schistosoma mansoni hypothetical protein 0.0032 0.0311 0.0775
Plasmodium vivax GNS1/SUR4 domain containing protein 0.067 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0055 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Loa Loa (eye worm) hypothetical protein 0.0273 0.3975 0.3973
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0046 0.0533 0.1333
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0032 0.0311 0.0308
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0032 0.0311 0.0308
Echinococcus granulosus acetylcholinesterase 0.0273 0.3975 1
Brugia malayi fatty acid elongation protein 3 0.0135 0.1886 0.1884
Brugia malayi Carboxylesterase family protein 0.0273 0.3975 0.3973
Echinococcus granulosus para nitrobenzyl esterase 0.0046 0.0533 0.1333
Loa Loa (eye worm) hypothetical protein 0.0135 0.1886 0.1884
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0047 0.054 0.1194
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Brugia malayi ORL1-like opioid receptor 0.0032 0.0311 0.0308
Onchocerca volvulus 0.0032 0.0311 0.1636
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Brugia malayi neuropeptide F receptor 0.0032 0.0311 0.0308
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0124 0.2288
Loa Loa (eye worm) ELO-9 protein 0.0135 0.1886 0.1884
Schistosoma mansoni hypothetical protein 0.0015 0.0055 0.0132
Echinococcus granulosus cathepsin l1 0.0017 0.0087 0.0212
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0032 0.0311 0.0706
Brugia malayi Cathepsin L-like precursor 0.0017 0.0087 0.0084
Schistosoma mansoni survival motor neuron protein 0.0047 0.0547 0.137
Schistosoma mansoni opsin-like receptor 0.0032 0.0311 0.0775
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0087 0.0212
Schistosoma mansoni BC026374 protein (S09 family) 0.0046 0.0533 0.1333
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0105 0.1434 0.1434
Onchocerca volvulus 0.0032 0.0311 0.1636
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0087 0.1588
Schistosoma mansoni tar DNA-binding protein 0.0059 0.0727 0.1823
Onchocerca volvulus Elongation of very long chain fatty acids protein homolog 0.0135 0.1886 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0032 0.0311 0.0775
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0105 0.1434 1
Brugia malayi RE15519p 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0047 0.054 0.3622
Leishmania major fatty acid elongase, putative 0.067 1 1
Plasmodium falciparum mitochondrial ATP synthase F1, epsilon subunit, putative 0.0017 0.0096 0.006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0087 0.1588
Echinococcus granulosus serotonin receptor 0.0032 0.0311 0.0775
Trypanosoma cruzi cytochrome P450, putative 0.0021 0.0156 0.0124
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0032 0.0311 0.0308
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Leishmania major fatty acid elongase, putative 0.0135 0.1886 0.1886
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0087 0.0084
Schistosoma mansoni hypothetical protein 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0314 0.0311
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.038 0.7117
Brugia malayi Cytochrome P450 family protein 0.0013 0.0033 0.003
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0156 0.0153
Leishmania major cathepsin L-like protease 0.0017 0.0087 0.0087
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0032 0.0311 0.1636
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus neuropeptides capa receptor 0.0032 0.0311 0.0775
Echinococcus multilocularis caspase 0.0072 0.0923 0.2258
Brugia malayi Cytochrome P450 family protein 0.0031 0.0302 0.0299
Loa Loa (eye worm) hypothetical protein 0.0146 0.2046 0.2043
Loa Loa (eye worm) fatty acid elongation protein 3 0.0135 0.1886 0.1884
Loa Loa (eye worm) hypothetical protein 0.0046 0.0537 0.0534
Toxoplasma gondii integral membrane protein, GNS1/SUR4 family protein, putative 0.067 1 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0046 0.0533 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0124 0.2288
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0055 0.0052
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0032 0.0311 0.0308
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0046 0.0533 0.1268
Echinococcus multilocularis cysteine protease 0.0017 0.0087 0.0138
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0105 0.1434 0.3601
Echinococcus granulosus acetylcholinesterase 0.0273 0.3975 1
Onchocerca volvulus 0.0032 0.0311 0.1636
Echinococcus granulosus tachykinin peptides receptor 99D 0.0032 0.0311 0.0775
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0046 0.0533 0.1333
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0059 0.0726 0.1632
Brugia malayi Muscleblind-like protein 0.0146 0.2046 0.2043
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0311 0.0775
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Trypanosoma brucei Metacaspase-4 0.0019 0.0124 0.0124
Loa Loa (eye worm) hypothetical protein 0.0146 0.2046 0.2043
Toxoplasma gondii cathepsin CPL 0.0017 0.0087 0.0055
Onchocerca volvulus 0.0032 0.0311 0.1636
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.038 0.0349
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0032 0.0311 0.0775
Echinococcus granulosus neuropeptide receptor 0.0032 0.0311 0.0775
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus g protein coupled receptor 0.0032 0.0311 0.0775
Onchocerca volvulus 0.0017 0.0087 0.0447
Echinococcus multilocularis rhodopsin orphan GPCR 0.0032 0.0311 0.0706
Plasmodium vivax elongation of very long chain fatty acids protein 3, putative 0.0135 0.1886 0.1857
Leishmania major cathepsin L-like protease 0.0017 0.0087 0.0087
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0595 0.0564
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus granulosus allatostatin A receptor 0.0032 0.0311 0.0775
Brugia malayi hypothetical protein 0.0032 0.0311 0.0308
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0087 0.0084
Trypanosoma cruzi fatty acid elongase, putative 0.0135 0.1886 0.186
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0046 0.0537 0.0534
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Onchocerca volvulus Cell death protein 3 homolog 0.0019 0.0124 0.0643
Echinococcus granulosus tm gpcr rhodopsin 0.0032 0.0311 0.0775
Schistosoma mansoni neuropeptide F-like receptor 0.0032 0.0311 0.0775
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0087 0.2232
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0802 0.0772
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0802 0.0802
Loa Loa (eye worm) GMP reductase 0.0047 0.054 0.0537
Schistosoma mansoni amine GPCR 0.0032 0.0311 0.0775
Loa Loa (eye worm) hypothetical protein 0.0032 0.0311 0.0308
Echinococcus multilocularis caspase 3 0.0053 0.0631 0.1519
Loa Loa (eye worm) hypothetical protein 0.0046 0.0533 0.053

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 70 % TP_TRANSPORTER: inhibition of carnitine uptake by Carnitine-related compound-14 at 20uM in Xenopus laevis oocytes ChEMBL. 12089149

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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