Detailed information for compound 944847

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 393.454 | Formula: C23H24FN3O2
  • H donors: 1 H acceptors: 1 LogP: 3.62 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CC1=C(N)O[C@]2([C@H]([C@@H]1c1ccc(cc1)F)CN(CC2)Cc1ccccc1)OC
  • InChi: 1S/C23H24FN3O2/c1-28-23-11-12-27(14-16-5-3-2-4-6-16)15-20(23)21(19(13-25)22(26)29-23)17-7-9-18(24)10-8-17/h2-10,20-21H,11-12,14-15,26H2,1H3/t20-,21+,23+/m0/s1
  • InChiKey: DAEDKSNRFADDAP-QZNHQXDQSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.1329 0.302
Schistosoma mansoni transient receptor potential channel 0.0043 0.0084 0.0084
Toxoplasma gondii cathepsin CPC1 0.0247 0.1329 0.1851
Echinococcus multilocularis calcium activated potassium channel 0.0044 0.0087 0.0087
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0084 0.0084
Brugia malayi Transient-receptor-potential like protein 0.0043 0.0084 0.0084
Echinococcus multilocularis conserved hypothetical protein 0.0043 0.0084 0.0084
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0034 0.0026 0.0026
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0247 0.1329 0.1746
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.1329 0.1329
Plasmodium vivax serine-repeat antigen (SERA) 0.0247 0.1329 0.1746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0247 0.1329 0.1329
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0087 0.0349 0.0349
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0247 0.1329 0.1746
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Loa Loa (eye worm) hypothetical protein 0.1143 0.6815 0.6815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.1329 0.1329
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0087 0.0349 0.0395
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0043 0.0084 0.0084
Plasmodium falciparum serine repeat antigen 6 0.0247 0.1329 0.1746
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Schistosoma mansoni 60S ribosomal protein L21 0.0103 0.0452 0.0452
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0043 0.0084 0.0084
Echinococcus granulosus cathepsin l cysteine peptidase 0.1143 0.6815 0.6815
Echinococcus granulosus potassium voltage gated channel subfamily H 0.019 0.0981 0.0981
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0821 0.4844 0.4844
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Echinococcus granulosus tyrosine protein kinase Src64B 0.0034 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.1664 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.1143 0.6815 0.6788
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.061 0.3553 0.3553
Plasmodium falciparum serine repeat antigen 7 0.0247 0.1329 0.1746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B (C01 family) 0.0247 0.1329 0.1329
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Echinococcus multilocularis hyperpolarization activated cyclic 0.013 0.0613 0.0613
Echinococcus granulosus two pore calcium channel protein 1 0.0043 0.0084 0.0084
Brugia malayi serine/threonine-protein kinase 6 0.0057 0.0169 0.0169
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.1329 0.1746
Schistosoma mansoni tyrosine kinase 0.0034 0.0026 0.0026
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0247 0.1329 0.1329
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0043 0.0084 0.0084
Echinococcus granulosus ryanodine receptor 44f 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.013 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Schistosoma mansoni voltage-gated ion channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.061 0.3553 0.5092
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.013 0.0613 0.0613
Echinococcus granulosus aurora kinase A 0.0057 0.0169 0.0169
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0169 0.0169
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.0087 0.0349 0.0271
Brugia malayi cathepsin L-like precursor 0.078 0.4591 0.4591
Trypanosoma brucei Flagellar Member 6 0.0087 0.0349 0.0395
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Echinococcus granulosus sodium channel protein 0.0043 0.0084 0.0084
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0043 0.0084 0.0084
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0247 0.1329 0.302
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Echinococcus granulosus cysteine protease 0.061 0.3553 0.3553
Onchocerca volvulus Cathepsin F homolog 0.1143 0.6815 1
Giardia lamblia Cysteine protease 0.0247 0.1329 0.302
Loa Loa (eye worm) hypothetical protein 0.078 0.4591 0.4591
Toxoplasma gondii aurora kinase 0.0057 0.0169 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.1329 0.1746
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.006 0.0188 0.0028
Echinococcus granulosus tyrosine protein kinase Lyn 0.0034 0.0028 0.0028
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.0087 0.0349 0.0349
Schistosoma mansoni hypothetical protein 0.0087 0.0349 0.0349
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0043 0.0084 0.0084
Brugia malayi hypothetical protein 0.0043 0.0084 0.0084
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0247 0.1329 0.1746
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0084 0.0084
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.0087 0.0349 0.0271
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Leishmania major protein kinase, putative 0.0087 0.0352 0.0399
Loa Loa (eye worm) hypothetical protein 0.0569 0.3299 0.3299
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.0087 0.0349 0.0271
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0084 0.0084
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0087 0.0349 0.0395
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Echinococcus multilocularis potassium large conductance calcium activated 0.0043 0.0084 0.0084
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.1329 0.1329
Leishmania major hypothetical protein, conserved 0.0087 0.0349 0.0395
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.013 0.0613 0.0613
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.0087 0.0349 0.0271
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.013 0.0613 0.0613
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0043 0.0084 0.0084
Schistosoma mansoni tyrosine kinase 0.0034 0.0026 0.0026
Brugia malayi Papain family cysteine protease containing protein 0.1143 0.6815 0.6815
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Giardia lamblia Cathepsin L-like protease 0.0247 0.1329 0.302
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Onchocerca volvulus Cathepsin L homolog 0.1143 0.6815 1
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Giardia lamblia Hypothetical protein 0.0247 0.1329 0.302
Brugia malayi Papain family cysteine protease containing protein 0.061 0.3553 0.3553
Echinococcus granulosus cGMP dependent protein kinase 1 0.0087 0.0352 0.0352
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.019 0.0981 0.0981
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0043 0.0084 0.0084
Mycobacterium tuberculosis Probable transcriptional regulatory protein Cmr 0.0087 0.0349 0.5
Plasmodium vivax vivapain-3 0.061 0.3553 0.5092
Mycobacterium tuberculosis Conserved hypothetical protein 0.0087 0.0349 0.5
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.0087 0.0349 0.0349
Echinococcus multilocularis voltage gated potassium channel 0.0043 0.0084 0.0084
Echinococcus granulosus cGMP dependent protein kinase 0.0087 0.0352 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.078 0.4591 0.6654
Schistosoma mansoni voltage-gated potassium channel 0.019 0.0981 0.0981
Trichomonas vaginalis adenylate cyclase type, putative 0.006 0.0188 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0087 0.0349 0.0271
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0352 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0612 0.3565 0.511
Trichomonas vaginalis adenylate cyclase type, putative 0.006 0.0188 0.0028
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0043 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Giardia lamblia Cysteine protease 0.0247 0.1329 0.302
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.078 0.4591 0.6654
Mycobacterium tuberculosis Probable glutamine-transport ATP-binding protein ABC transporter GlnQ 0.0087 0.0349 0.5
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0247 0.1329 0.1329
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Schistosoma mansoni cathepsin F (C01 family) 0.078 0.4591 0.4591
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0247 0.1329 0.1746
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.061 0.3553 0.3553
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis adenylate cyclase type, putative 0.006 0.0188 0.0028
Giardia lamblia Cathepsin B precursor 0.0685 0.4011 1
Toxoplasma gondii cathepsin CPC2 0.0247 0.1329 0.1851
Echinococcus multilocularis voltage dependent calcium channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Echinococcus multilocularis c src tyrosine kinase 0.0034 0.0026 0.0026
Trichomonas vaginalis adenylate cyclase type IX, putative 0.006 0.0188 0.0028
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0247 0.1329 0.1746
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0084 0.0084
Echinococcus granulosus cathepsin L cysteine proteinase 0.1143 0.6815 0.6815
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Onchocerca volvulus 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Plasmodium falciparum serine repeat antigen 1 0.0247 0.1329 0.1746
Echinococcus multilocularis cathepsin b 0.1664 1 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0349 0.0349
Echinococcus granulosus hypothetical protein 0.0043 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0247 0.1329 0.1746
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.0087 0.0349 0.0349
Schistosoma mansoni transient receptor potential channel 0.0043 0.0084 0.0084
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0084 0.0084
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0247 0.1329 0.1746
Schistosoma mansoni calcium-activated potassium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus cathepsin l1 0.1143 0.6815 0.6815
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.0087 0.0349 0.0349
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Brugia malayi serine/threonine protein kinase 6 0.0057 0.0169 0.0169
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Trypanosoma cruzi cysteine proteinase, putative 0.061 0.3553 0.3499
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0034 0.0026 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.0087 0.0349 0.0349
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.0087 0.0349 0.0349
Trichomonas vaginalis adenylyl cyclase type V, putative 0.006 0.0188 0.0028
Echinococcus granulosus calcium activated potassium channel 0.0044 0.0087 0.0087
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0821 0.4844 0.4844
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0034 0.0026 0.0026
Schistosoma mansoni voltage-gated potassium channel 0.0715 0.4197 0.4197
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.013 0.0613 0.0613
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus potassium large conductance calcium activated 0.0043 0.0084 0.0084
Schistosoma mansoni tyrosine kinase 0.0034 0.0026 0.0026
Brugia malayi cation channel family protein 0.0043 0.0084 0.0084
Echinococcus multilocularis two pore calcium channel protein 2 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Echinococcus multilocularis cathepsin L cysteine protease 0.1143 0.6815 0.6815
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trypanosoma cruzi cruzipain precursor, putative 0.0363 0.2044 0.1977
Plasmodium falciparum cysteine proteinase falcipain 2a 0.1143 0.6815 1
Brugia malayi Tyrosine-protein kinase abl-1 0.0034 0.0026 0.0026
Echinococcus multilocularis cathepsin L cysteine protease 0.1143 0.6815 0.6815
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Brugia malayi fibroinase precursor 0.0247 0.1329 0.1329
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.013 0.0613 0.0668
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.0061 0.0191 0.0159
Loa Loa (eye worm) SRC-1 0.0034 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Brugia malayi N-terminal motif family protein 0.0087 0.0349 0.0349
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.013 0.0613 0.0613
Loa Loa (eye worm) ryanodine receptor 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Giardia lamblia Cathepsin B precursor 0.0685 0.4011 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1143 0.6815 1
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.013 0.0613 0.0613
Entamoeba histolytica cysteine proteinase, putative 0.061 0.3553 0.5092
Plasmodium vivax unspecified product 0.0247 0.1329 0.1746
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0685 0.4011 0.3961
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0655 0.3829 0.3829
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0087 0.0349 0.0349
Echinococcus multilocularis two pore calcium channel protein 1 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0087 0.0349 0.0395
Entamoeba histolytica cysteine proteinase, putative 0.061 0.3553 0.5092
Loa Loa (eye worm) AUR protein kinase 0.0057 0.0169 0.0169
Mycobacterium ulcerans transmembrane transport protein 0.0087 0.0349 0.5
Trypanosoma cruzi protein kinase A regulatory subunit 0.0087 0.0349 0.0268
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0034 0.0026 0.0026
Entamoeba histolytica cysteine proteinase, putative 0.061 0.3553 0.5092
Schistosoma mansoni cathepsin F (C01 family) 0.1143 0.6815 0.6815
Schistosoma mansoni voltage-gated cation channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine proteinase, putative 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0247 0.1329 0.1746
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.061 0.3553 0.5092
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0087 0.0349 0.0349
Leishmania major hypothetical protein, conserved 0.0087 0.0349 0.0395
Onchocerca volvulus 0.0087 0.0349 0.0395
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.006 0.0188 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0363 0.2044 0.1977
Toxoplasma gondii preprocathepsin c precursor, putative 0.0247 0.1329 0.1851
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0655 0.3829 0.3829
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0043 0.0084 0.0084
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.013 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.013 0.0613 0.0613
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0084 0.0084
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0043 0.0084 0.0084
Loa Loa (eye worm) cysteine protease 0.1143 0.6815 0.6815
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.019 0.0981 0.0981
Entamoeba histolytica hypothetical protein 0.0247 0.1329 0.1746
Echinococcus granulosus patatin phospholipase domain containing protein 0.0087 0.0349 0.0349
Onchocerca volvulus 0.1143 0.6815 1
Echinococcus granulosus voltage dependent calcium channel 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1664 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0352 0.0352
Echinococcus granulosus voltage gated potassium channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Echinococcus granulosus cyclic nucleotide gated cation channel 0.013 0.0613 0.0613
Chlamydia trachomatis cAMP-dependent protein kinase regulatory subunit 0.0087 0.0349 0.5
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0247 0.1329 0.1329
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.0087 0.0349 0.0349
Trypanosoma cruzi cAMP binding protein, putative 0.0087 0.0349 0.0268
Echinococcus granulosus hyperpolarization activated cyclic 0.013 0.0613 0.0613
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Schistosoma mansoni transient receptor potential channel 4 0.0043 0.0084 0.0084
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.013 0.0613 0.0613
Entamoeba histolytica cysteine proteinase, putative 0.078 0.4591 0.6654
Mycobacterium ulcerans transcriptional regulatory protein 0.0087 0.0349 0.5
Echinococcus multilocularis voltage gated potassium channel 0.019 0.0981 0.0981
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0087 0.0349 0.0395
Plasmodium vivax vivapain-2 0.1143 0.6815 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Schistosoma mansoni hypothetical protein 0.006 0.0188 0.0188
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0084 0.0084
Echinococcus granulosus tyrosine protein kinase Src42A 0.0034 0.0026 0.0026
Echinococcus granulosus cGMP dependent protein kinase 1 0.0087 0.0352 0.0352
Echinococcus multilocularis voltage dependent calcium channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Onchocerca volvulus 0.078 0.4591 0.6696
Brugia malayi Papain family cysteine protease containing protein 0.061 0.3553 0.3553
Echinococcus multilocularis cysteine protease 0.1143 0.6815 0.6815
Mycobacterium tuberculosis Probable conserved transmembrane transport protein 0.0087 0.0349 0.5
Onchocerca volvulus 0.1143 0.6815 1
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.006 0.0188 0.0188
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin S (C01 family) 0.0247 0.1329 0.1329
Trypanosoma cruzi cysteine protease, putative 0.061 0.3553 0.3499
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.1143 0.6815 1
Echinococcus granulosus cathepsin L 0.0247 0.1329 0.1329
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0685 0.4011 0.5835
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.006 0.0188 0.0028
Echinococcus granulosus cathepsin L 0.061 0.3553 0.3553
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1143 0.6815 0.6815
Trypanosoma cruzi cAMP response protein 1 0.0087 0.0349 0.0268
Loa Loa (eye worm) hypothetical protein 0.019 0.0981 0.0981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0247 0.1329 0.1746
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase type IX, putative 0.006 0.0188 0.0028
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Brugia malayi cathepsin L precursor 0.0247 0.1329 0.1329
Echinococcus granulosus two pore calcium channel protein 2 0.0043 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0034 0.0026 0.0026
Echinococcus multilocularis aurora kinase A 0.0057 0.0169 0.0169
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.019 0.0981 0.0981
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Toxoplasma gondii cathepsin CPL 0.1143 0.6815 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Echinococcus multilocularis cathepsin b 0.1664 1 1
Loa Loa (eye worm) AGC/PKG protein kinase 0.0087 0.0352 0.0352
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.1329 0.1329
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.1329 0.1746
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0363 0.2044 0.2044
Trypanosoma cruzi cysteine peptidase, putative 0.1143 0.6815 0.6788
Mycobacterium ulcerans hypothetical protein 0.0087 0.0349 0.5
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-dependent calcium channel 0.0043 0.0084 0.0084
Echinococcus granulosus hyperpolarization activated cyclic 0.013 0.0613 0.0613
Entamoeba histolytica cysteine protease, putative 0.1143 0.6815 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0043 0.0084 0.0084
Echinococcus multilocularis patatin phospholipase domain containing protein 0.0087 0.0349 0.0349
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.0087 0.0349 0.0395
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0247 0.1329 0.1746
Plasmodium falciparum serine repeat antigen 3 0.0247 0.1329 0.1746
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.1329 0.1329
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.1329 0.1329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Mycobacterium leprae Conserved hypothetical protein 0.0087 0.0349 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0043 0.0084 0.0084
Brugia malayi cathepsin Z-like cysteine proteinase 0.0247 0.1329 0.1329
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.1329 0.302
Plasmodium falciparum serine repeat antigen 9 0.0247 0.1329 0.1746
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0043 0.0084 0.0084
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.013 0.0613 0.0613
Giardia lamblia Cathepsin B precursor 0.0247 0.1329 0.302
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Mycobacterium ulcerans hypothetical protein 0.0087 0.0349 0.5
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.013 0.0613 0.0613
Giardia lamblia Cathepsin B precursor 0.0247 0.1329 0.302
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0087 0.0349 0.0395
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0087 0.0349 0.0349
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0247 0.1329 0.1746
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1664 1 1
Trichomonas vaginalis adenylate cyclase type VI, putative 0.006 0.0188 0.0028
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0247 0.1329 0.1746
Trypanosoma brucei protein kinase A regulatory subunit 0.0087 0.0349 0.0395
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1664 1 1
Trypanosoma brucei aurora B kinase 0.0057 0.0169 0.0127
Brugia malayi cathepsin F-like cysteine proteinase 0.0247 0.1329 0.1329
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.006 0.0188 0.0028
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Schistosoma mansoni voltage-gated potassium channel 0.0103 0.0452 0.0452
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Echinococcus granulosus single minded 2 0.006 0.0188 0.0188
Loa Loa (eye worm) papain family cysteine protease containing protein 0.1143 0.6815 0.6815
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0087 0.0349 0.0349
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.061 0.3553 0.3499
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Brugia malayi cathepsin L-like cysteine proteinase 0.0247 0.1329 0.1329
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0043 0.0084 0.0084
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.0087 0.0349 0.0349
Plasmodium falciparum cGMP-dependent protein kinase 0.0087 0.0352 0.0275
Giardia lamblia Cathepsin B precursor 0.0247 0.1329 0.302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Mycobacterium ulcerans hypothetical protein 0.0087 0.0349 0.5
Trichomonas vaginalis adenylate cyclase type III, putative 0.006 0.0188 0.0028
Trypanosoma cruzi cAMP response protein 1, putative 0.0087 0.0349 0.0268
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0043 0.0084 0.0084
Echinococcus multilocularis transfer RNA-Gly 0.0043 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Brugia malayi cation channel family protein 0.0043 0.0084 0.0084
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0084 0.0084
Giardia lamblia Cathepsin B precursor 0.0247 0.1329 0.302
Mycobacterium ulcerans hypothetical protein 0.0087 0.0349 0.5
Giardia lamblia Hypothetical protein 0.0247 0.1329 0.302
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.0087 0.0352 0.0399
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0043 0.0084 0.0084
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.0087 0.0349 0.0271
Trypanosoma brucei cAMP binding protein, putative 0.0087 0.0349 0.0395
Schistosoma mansoni ryanodine receptor related 0.0043 0.0084 0.0084
Plasmodium vivax unspecified product 0.0363 0.2044 0.2821
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Echinococcus multilocularis ryanodine receptor 44f 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.1329 0.1746
Schistosoma mansoni cathepsin s 0.0363 0.2044 0.2044
Leishmania major cysteine peptidase A (CPA) 0.1143 0.6815 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Plasmodium vivax vivapain-1 0.061 0.3553 0.5092
Plasmodium falciparum cysteine proteinase falcipain 1 0.061 0.3553 0.5092
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0247 0.1329 0.1746
Loa Loa (eye worm) voltage-gated calcium channel 0.0043 0.0084 0.0084
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0247 0.1329 0.1329
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.0087 0.0349 0.0349
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0247 0.1329 0.1746
Brugia malayi olfactory channel protein osm-9 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1664 1 1
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0043 0.0084 0.0084
Plasmodium falciparum serine repeat antigen 2 0.0247 0.1329 0.1746
Echinococcus granulosus cyclic nucleotide gated cation channel 0.013 0.0613 0.0613
Onchocerca volvulus 0.0087 0.0349 0.0395
Loa Loa (eye worm) voltage-dependent calcium channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) AUR protein kinase 0.0057 0.0169 0.0169
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0043 0.0084 0.0084
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.061 0.3553 0.5154
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Toxoplasma gondii cathepsin B 0.0685 0.4011 0.5835
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0247 0.1329 0.1746
Schistosoma mansoni similar to Protein C20orf152 homolog 0.0087 0.0349 0.0349
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0057 0.0169 0.0169
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0247 0.1329 0.1746
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.0087 0.0349 0.0395
Echinococcus multilocularis transient receptor potential gamma protein 0.0043 0.0084 0.0084
Echinococcus granulosus cathepsin b 0.1664 1 1
Schistosoma mansoni voltage-gated potassium channel 0.0715 0.4197 0.4197
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0247 0.1329 0.1746
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis adenylate cyclase type IX, putative 0.006 0.0188 0.0028
Trypanosoma cruzi cysteine proteinase, putative 0.061 0.3553 0.3499
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Trypanosoma cruzi cysteine peptidase, putative 0.1143 0.6815 0.6788
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis adenylate cyclase type III, putative 0.006 0.0188 0.0028
Treponema pallidum catabolite gene activator (Crp) 0.0087 0.0349 0.5
Echinococcus multilocularis cathepsin L 0.0247 0.1329 0.1329
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0087 0.0349 0.0349
Echinococcus multilocularis potassium voltage gated channel protein 0.0043 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0087 0.0352 0.0352
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Trypanosoma brucei cAMP response protein 1, putative 0.0087 0.0349 0.0395
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.0087 0.0349 0.0349
Trypanosoma cruzi major cysteine proteinase, putative 0.0247 0.1329 0.1256
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0247 0.1329 0.1746
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0685 0.4011 0.5781
Treponema pallidum cyclic nucleotide binding protein 0.0087 0.0349 0.5
Onchocerca volvulus 0.1143 0.6815 1
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Plasmodium vivax serine-repeat antigen (SERA) 0.0247 0.1329 0.1746
Brugia malayi Cathepsin L-like precursor 0.078 0.4591 0.4591
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0034 0.0026 0.0026
Schistosoma mansoni protein kinase 0.0057 0.0169 0.0169
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Schistosoma mansoni transient receptor potential channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) calcium channel 0.0043 0.0084 0.0084
Echinococcus granulosus voltage gated potassium channel 0.019 0.0981 0.0981
Mycobacterium tuberculosis Conserved hypothetical protein 0.0087 0.0349 0.5
Onchocerca volvulus 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.0087 0.0349 0.0349
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.0087 0.0349 0.0468
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0363 0.2044 0.2044
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Schistosoma mansoni two-pore calcium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Onchocerca volvulus Cathepsin L homolog 0.0247 0.1329 0.1851
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.006 0.0188 0.0028
Schistosoma mansoni tyrosine kinase 0.0806 0.4755 0.4755
Schistosoma mansoni serine/threonine protein kinase 0.0087 0.0352 0.0352
Echinococcus granulosus c src tyrosine kinase 0.0034 0.0026 0.0026
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0084 0.0084
Echinococcus granulosus sodium leak channel non selective protein 0.0043 0.0084 0.0084
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0057 0.0169 0.0169
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Echinococcus multilocularis sodium channel protein 0.0043 0.0084 0.0084
Echinococcus granulosus cathepsin L cysteine protease 0.061 0.3553 0.3553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0087 0.0349 0.0349
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0655 0.3829 0.3829
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0349 0.0349
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0084 0.0084
Brugia malayi ion channel NompC 0.0043 0.0084 0.0084
Loa Loa (eye worm) voltage-gated potassium channel 0.0043 0.0084 0.0084
Echinococcus granulosus TRP transient receptor potential channel 0.0043 0.0084 0.0084
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0247 0.1329 0.302
Onchocerca volvulus 0.0247 0.1329 0.1851
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0087 0.0349 0.0271
Echinococcus granulosus shaker cognate 0.0043 0.0084 0.0084
Entamoeba histolytica cysteine proteinase 2 0.061 0.3553 0.5092
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Echinococcus granulosus cathepsin b 0.1664 1 1
Echinococcus granulosus voltage gated hydrogen channel 1 0.0043 0.0084 0.0084
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0247 0.1329 0.1256
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0247 0.1329 0.1329
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0247 0.1329 0.1329
Trypanosoma cruzi aurora B kinase, putative 0.0057 0.0169 0.0086
Brugia malayi Papain family cysteine protease containing protein 0.0247 0.1329 0.1329
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.013 0.0613 0.0613
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.0087 0.0349 0.0268
Plasmodium falciparum serine repeat antigen 5 0.0247 0.1329 0.1746
Echinococcus multilocularis hyperpolarization activated cyclic 0.013 0.0613 0.0613
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0247 0.1329 0.1746
Onchocerca volvulus 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0043 0.0084 0.0084
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0087 0.0349 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Loa Loa (eye worm) hypothetical protein 0.0363 0.2044 0.2044
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.0087 0.0349 0.0395
Plasmodium vivax unspecified product 0.061 0.3553 0.5092
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0247 0.1329 0.1329
Loa Loa (eye worm) hypothetical protein 0.0363 0.2044 0.2044
Giardia lamblia Cathepsin L-like protease 0.0247 0.1329 0.302
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.061 0.3553 0.3499
Leishmania major protein kinase, putative 0.0087 0.0352 0.0399
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.1143 0.6815 0.6815
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0612 0.3565 0.511
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0247 0.1329 0.1329
Schistosoma mansoni tyrosine kinase 0.0034 0.0026 0.0026
Echinococcus granulosus transient receptor potential gamma protein 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.0087 0.0349 0.0349
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0087 0.0349 0.0349
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Loa Loa (eye worm) ctsf protein 0.1143 0.6815 0.6815
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.0087 0.0349 0.0349
Entamoeba histolytica cysteine protease, putative 0.0247 0.1329 0.1746
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Leishmania major hypothetical protein, unknown function 0.0087 0.0349 0.0395
Leishmania major protein kinase, putative 0.0057 0.0169 0.0127
Trichomonas vaginalis hypothetical protein 0.006 0.0188 0.0028
Trichomonas vaginalis adenylate cyclase type IX, putative 0.006 0.0188 0.0028
Echinococcus granulosus potassium voltage gated channel protein 0.0043 0.0084 0.0084
Onchocerca volvulus 0.1143 0.6815 1
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.061 0.3553 0.3553
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0034 0.0026 0.0026
Plasmodium vivax vivapain-2 0.1143 0.6815 1
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0087 0.0352 0.0352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.1143 0.6815 1
Echinococcus multilocularis short transient receptor potential channel 6 0.0043 0.0084 0.0084
Giardia lamblia Cathepsin B precursor 0.0685 0.4011 1
Trypanosoma cruzi cruzipain precursor, putative 0.1143 0.6815 0.6788
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0034 0.0026 0.0026
Echinococcus granulosus tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Brugia malayi voltage-dependent calcium channel 0.0043 0.0084 0.0084
Plasmodium falciparum serine repeat antigen 8 0.0247 0.1329 0.1746
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Brugia malayi SRC-1 0.0034 0.0026 0.0026
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.1143 0.6815 1
Loa Loa (eye worm) cathepsin B 0.0685 0.4011 0.4011
Brugia malayi Cathepsin L-like precursor 0.1143 0.6815 0.6815
Leishmania major protein kinase A regulatory subunit, putative 0.0087 0.0349 0.0395
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.006 0.0188 0.0028
Brugia malayi Cyclic-nucleotide gated cation channel 0.013 0.0613 0.0613
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0247 0.1329 0.1329
Entamoeba histolytica cysteine proteinase 1, putative 0.061 0.3553 0.5092
Trypanosoma cruzi cysteine peptidase, putative 0.1143 0.6815 0.6788
Onchocerca volvulus Cathepsin L homolog 0.1143 0.6815 1
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0087 0.0349 0.0268
Entamoeba histolytica cysteine protease, putative 0.061 0.3553 0.5092
Echinococcus multilocularis expressed conserved protein 0.0087 0.0352 0.0352
Loa Loa (eye worm) fibroinase 0.1143 0.6815 0.6815
Schistosoma mansoni vesicular amine transporter 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.078 0.4591 0.4591
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0043 0.0084 0.0084
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0247 0.1329 0.1746
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Leishmania major cyclic nucleotide-binding protein-like protein 0.0087 0.0349 0.0395
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0034 0.0026 0.0026
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0043 0.0084 0.0084
Echinococcus multilocularis tyrosine protein kinase Abl 0.0034 0.0026 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0247 0.1329 0.1746
Plasmodium falciparum cysteine proteinase falcipain 2b 0.1143 0.6815 1
Schistosoma mansoni cathepsin F (C01 family) 0.1143 0.6815 0.6815
Brugia malayi Cathepsin L-like precursor 0.078 0.4591 0.4591
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Loa Loa (eye worm) ion channel NompC 0.0043 0.0084 0.0084
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.0087 0.0349 0.0349
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0247 0.1329 0.1746
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0655 0.3829 0.3829
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.0087 0.0349 0.0349
Echinococcus multilocularis cysteine protease 0.1143 0.6815 0.6815
Echinococcus multilocularis cathepsin L 0.061 0.3553 0.3553
Schistosoma mansoni voltage-gated potassium channel 0.0043 0.0084 0.0084
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.078 0.4591 0.4545
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.013 0.0613 0.0613
Loa Loa (eye worm) AUR protein kinase 0.0057 0.0169 0.0169
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1143 0.6815 1
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Trichomonas vaginalis guanylate cyclase, putative 0.006 0.0188 0.0028
Treponema pallidum cyclic nucleotide binding protein 0.0087 0.0349 0.5
Loa Loa (eye worm) hypothetical protein 0.078 0.4591 0.4591
Mycobacterium tuberculosis Conserved protein 0.0087 0.0349 0.5
Giardia lamblia Encystation-specific protease 0.0247 0.1329 0.302
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0043 0.0084 0.0084
Echinococcus multilocularis sodium leak channel non selective protein 0.0043 0.0084 0.0084
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.013 0.0613 0.0668
Entamoeba histolytica cysteine proteinase, putative 0.1143 0.6815 1
Giardia lamblia Cathepsin L precursor 0.0247 0.1329 0.302
Echinococcus multilocularis transient receptor potential cation channel 0.0043 0.0084 0.0084
Echinococcus granulosus cathepsin l1 0.078 0.4591 0.4591
Echinococcus granulosus short transient receptor potential channel 6 0.0043 0.0084 0.0084
Brugia malayi Cathepsin L-like precursor 0.0363 0.2044 0.2044
Echinococcus multilocularis cathepsin l cysteine peptidase 0.1143 0.6815 0.6815
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0363 0.2044 0.2044
Schistosoma mansoni cathepsin C 0.0247 0.1329 0.1329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.061 0.3553 0.5154
Echinococcus granulosus transient receptor potential cation channel 0.0043 0.0084 0.0084
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.0087 0.0349 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0188 0.0028
Schistosoma mansoni hypothetical protein 0.0043 0.0084 0.0084
Echinococcus granulosus voltage dependent calcium channel 0.0043 0.0084 0.0084
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0043 0.0084 0.0084
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0043 0.0084 0.0084
Brugia malayi cathepsin F-like cysteine proteinase 0.0363 0.2044 0.2044
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0247 0.1329 0.1746
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.0087 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0084
Trypanosoma cruzi Flagellar Member 6 0.0087 0.0349 0.0268
Treponema pallidum catabolite gene activator 0.0087 0.0349 0.5
Brugia malayi Cathepsin L-like cysteine proteinase 0.078 0.4591 0.4591
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0043 0.0084 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0087 0.0349 0.0271
Giardia lamblia Cysteine protease 0.0247 0.1329 0.302
Leishmania major cathepsin L-like protease 0.1143 0.6815 1
Plasmodium falciparum serine repeat antigen 4 0.0247 0.1329 0.1746
Echinococcus multilocularis shaker cognate 0.0043 0.0084 0.0084
Plasmodium falciparum cysteine proteinase falcipain 3 0.1143 0.6815 1
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.006 0.0188 0.0028
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.006 0.0188 0.0028
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.006 0.0188 0.0028
Loa Loa (eye worm) hypothetical protein 0.0247 0.1329 0.1329
Leishmania major hypothetical protein, conserved 0.0087 0.0349 0.0395
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0685 0.4011 0.4011
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0034 0.0026 0.0026
Brugia malayi Egg laying defective protein 4 0.0087 0.0352 0.0352
Brugia malayi serine/threonine kinase 12 0.0057 0.0169 0.0169
Leishmania major regulatory subunit of protein kinase a-like protein 0.0087 0.0349 0.0395
Trypanosoma brucei cysteine peptidase C (CPC) 0.0685 0.4011 0.5835
Mycobacterium ulcerans regulatory protein 0.0087 0.0349 0.5
Giardia lamblia Cathepsin B precursor 0.0247 0.1329 0.302
Giardia lamblia Cysteine protease 0.0247 0.1329 0.302
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0043 0.0084 0.0084
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1664 1 1
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0087 0.0349 0.0268
Trichomonas vaginalis adenylate cyclase, putative 0.006 0.0188 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.061 0.3553 0.5092

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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