Detailed information for compound 988009

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 348.481 | Formula: C23H28N2O
  • H donors: 0 H acceptors: 1 LogP: 3.94 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1Cc2c(N1CCCCN1CCCC(C1)c1ccccc1)cccc2
  • InChi: 1S/C23H28N2O/c26-23-17-20-11-4-5-13-22(20)25(23)16-7-6-14-24-15-8-12-21(18-24)19-9-2-1-3-10-19/h1-5,9-11,13,21H,6-8,12,14-18H2
  • InChiKey: ZKPFKNIFSQQQET-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled Starlite/ChEMBL References
Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma mansoni biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis biogenic amine (5HT) receptor Get druggable targets OG5_133074 All targets in OG5_133074
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus multilocularis serotonin receptor Get druggable targets OG5_133249 All targets in OG5_133249
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133074 All targets in OG5_133074
Echinococcus granulosus biogenic amine 5HT receptor Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum Octopamine receptor, putative Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum expressed protein Get druggable targets OG5_133249 All targets in OG5_133249
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133249 All targets in OG5_133249
Schistosoma japonicum ko:K04153 5-hydroxytryptamine (serotonin) receptor 1A, putative Get druggable targets OG5_133249 All targets in OG5_133249
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0267 0.0534
Plasmodium vivax SET domain protein, putative 0.0033 0.0521 0.5554
Brugia malayi Cytochrome P450 family protein 0.0022 0.0267 0.0289
Brugia malayi hypothetical protein 0.0016 0.0137 0.0022
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.3261 0.3242
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0777 0.075
Schistosoma mansoni biogenic amine (5HT) receptor 0.046 1 1
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0022 0.0267 0.0044
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0127 0.0098
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0484 0.0965
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0073 0.1413 0.1388
Onchocerca volvulus 0.0263 0.5631 1
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0484 0.2774
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0126 0.0097
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0836 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0022 0.0267 0.0308
Brugia malayi Pax transcription factor protein 2 0.0235 0.501 1
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0022 0.0267 0.0044
Schistosoma mansoni cytochrome P450 0.0022 0.0267 0.0239
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0331 0.288
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0022 0.0267 0.0308
Brugia malayi Cytochrome P450 family protein 0.0022 0.0267 0.0289
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0022 0.0267 0.0044
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0022 0.0267 0.0308
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0777 0.1333
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0022 0.0267 0.0044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0022 0.0267 0.0044
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0127 0.0253
Echinococcus multilocularis 0.0022 0.0267 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0022 0.0267 0.0308
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0836 0.1092
Loa Loa (eye worm) hypothetical protein 0.0025 0.0331 0.0661
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0161 0.3362 0.3342
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0484 0.0965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0777 0.075
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0248 0.0942
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0073 0.1413 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0126 0.0097
Brugia malayi hypothetical protein 0.0025 0.0331 0.0419
Schistosoma mansoni biogenic amine (5HT) receptor 0.0153 0.3175 0.3155
Loa Loa (eye worm) hypothetical protein 0.0153 0.3175 0.6338
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0073 0.1413 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0022 0.0267 0.0308
Echinococcus granulosus geminin 0.0188 0.3967 0.3949
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0022 0.0267 0.0044
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0126 0.0097
Loa Loa (eye worm) hypothetical protein 0.0049 0.0866 0.1729
Loa Loa (eye worm) hypothetical protein 0.0033 0.0521 0.1039
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0073 0.1413 0.2821
Toxoplasma gondii cytochrome p450 superfamily protein 0.0022 0.0267 0.1982
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0777 0.075
Entamoeba histolytica acetyltransferase, GNAT family 0.0043 0.0748 0.4293
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0248 0.0266
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0248 0.0219
Mycobacterium leprae PROBABLE ATP SYNTHASE A CHAIN ATPB (PROTEIN 6) 0.0221 0.4692 1
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0022 0.0267 0.0308
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0248 0.0616
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0777 0.1551
Schistosoma mansoni hypothetical protein 0.0022 0.0267 0.0239
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0022 0.0267 0.0044
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0231 0.4922 0.9824
Loa Loa (eye worm) acetyltransferase 0.0161 0.3362 0.6711
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0494 0.0466
Mycobacterium tuberculosis Probable ATP synthase a chain AtpB (protein 6) 0.0221 0.4692 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0126 0.0252
Schistosoma mansoni hypothetical protein 0.0104 0.2096 0.2073
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0331 0.3287
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0248 0.0219
Schistosoma mansoni hypothetical protein 0.0188 0.3967 0.3949
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0126 0.0097
Echinococcus granulosus biogenic amine 5HT receptor 0.0153 0.3175 0.3155
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0022 0.0267 0.0044
Toxoplasma gondii exonuclease III APE 0.0021 0.0248 0.1709
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0565 0.0537
Leishmania major cytochrome p450-like protein 0.0022 0.0267 0.1093
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0866 0.1729
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0022 0.0267 0.0308
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0521 0.0493
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0267 0.1093
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0022 0.0267 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0521 0.0493
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0331 0.1588
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0331 0.1037
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0565 0.0537
Brugia malayi Pre-SET motif family protein 0.0231 0.4922 0.982
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0022 0.0267 0.0308
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0248 0.5
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0331 0.1588
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0022 0.0267 0.0308
Schistosoma mansoni ap endonuclease 0.0021 0.0248 0.0219
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0022 0.0267 0.0308
Brugia malayi Cytochrome P450 family protein 0.0032 0.0484 0.0732
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0331 0.3287
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Loa Loa (eye worm) pax transcription factor protein 2 0.0235 0.501 1
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0022 0.0267 0.0714
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0248 0.195
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0836 0.0809
Trypanosoma brucei RNA helicase, putative 0.0104 0.2096 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0248 0.0942
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0022 0.0267 0.0044
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0022 0.0267 0.0308
Brugia malayi acetyltransferase, GNAT family protein 0.0161 0.3362 0.6626
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0022 0.0267 0.0308
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0521 0.0493
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0484 0.2774
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0022 0.0267 0.0308
Leishmania major cytochrome p450-like protein 0.0022 0.0267 0.1093
Brugia malayi MH2 domain containing protein 0.0117 0.2376 0.4607
Brugia malayi hypothetical protein 0.0035 0.0565 0.0898
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0127 0.0001
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0727 0.07
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0524 0.0814
Echinococcus granulosus GPCR family 2 0.0015 0.0126 0.0097
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0022 0.0267 0.0044
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0836 1
Mycobacterium ulcerans F0F1 ATP synthase subunit A 0.0221 0.4692 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0484 0.053
Schistosoma mansoni hypothetical protein 0.0188 0.3967 0.3949
Giardia lamblia Histone acetyltransferase GCN5 0.0043 0.0748 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0248 0.0495
Entamoeba histolytica hypothetical protein 0.0035 0.0565 0.272
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0777 0.075
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0127 0.0098
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0073 0.1413 0.2636
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 0.6534
Loa Loa (eye worm) hypothetical protein 0.0033 0.0524 0.1045
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0521 0.5554
Schistosoma mansoni hypothetical protein 0.0035 0.0565 0.0537
Echinococcus multilocularis serotonin receptor 0.0153 0.3175 0.3155
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0022 0.0267 0.0044
Leishmania major hypothetical protein, conserved 0.0025 0.0331 0.1588
Brugia malayi Cytochrome P450 family protein 0.0032 0.0484 0.0732
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0836 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0022 0.0267 0.0044
Schistosoma mansoni ATP synthase F0 subunit 6 0.0221 0.4692 0.4676
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0248 0.0942
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0866 0.1515
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0022 0.0267 0.1093
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0565 0.0537
Brugia malayi isocitrate dehydrogenase 0.0015 0.0127 0.0001
Onchocerca volvulus 0.0235 0.501 0.8784
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0727 0.07
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0022 0.0267 0.0308
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0022 0.0267 0.0308
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0022 0.0267 0.0044
Echinococcus multilocularis biogenic amine (5HT) receptor 0.046 1 1
Schistosoma mansoni ap endonuclease 0.0021 0.0248 0.0219
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0073 0.1413 0.1388
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0022 0.0267 0.0308
Schistosoma mansoni hypothetical protein 0.0033 0.0524 0.0496
Loa Loa (eye worm) hypothetical protein 0.0153 0.3175 0.6338
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.2376 0.4743
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0484 0.1812
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0022 0.0267 0.0308
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0484 0.0965
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0022 0.0267 0.1093
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0073 0.1413 1
Brugia malayi Pre-SET motif family protein 0.0033 0.0521 0.0808
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0022 0.0267 0.0308
Echinococcus granulosus cytochrome P450 2K1 0.0022 0.0267 0.0239
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0022 0.0267 0.0044
Echinococcus multilocularis serotonin receptor 0.0153 0.3175 0.3155
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0161 0.3362 0.3342
Echinococcus multilocularis GPCR, family 2 0.0015 0.0126 0.0097
Loa Loa (eye worm) hypothetical protein 0.0015 0.0126 0.0252
Schistosoma mansoni hypothetical protein 0.0015 0.0126 0.0097
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0777 0.075
Plasmodium falciparum histone acetyltransferase GCN5 0.0043 0.0748 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0521 0.0493
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0521 0.0493
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0248 0.0249
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.2376 0.4743
Brugia malayi cytochrome P450 0.0022 0.0267 0.0289
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0127 0.0098
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0022 0.0267 0.1093
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0022 0.0267 0.0308
Trichomonas vaginalis set domain proteins, putative 0.0263 0.5631 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0836 0.1092
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0022 0.0267 0.0044
Echinococcus multilocularis geminin 0.0188 0.3967 0.3949
Wolbachia endosymbiont of Brugia malayi ATP synthase F0F1 subunit A 0.0221 0.4692 1
Leishmania major cytochrome p450-like protein 0.0032 0.0484 0.2774
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0248 0.1709
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0866 0.1515
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0331 0.288
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0127 0.0098
Loa Loa (eye worm) cytochrome P450 0.0022 0.0267 0.0534
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0022 0.0267 0.0044
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0022 0.0267 0.0044
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0073 0.1413 0.1388

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 193 nM Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHOK1 cells ChEMBL. 19326916
Ki (binding) > 1000 nM Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in HEK293 cells ChEMBL. 19326916

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.