Detailed information for compound 998117

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 409.519 | Formula: C28H27NO2
  • H donors: 2 H acceptors: 2 LogP: 7.58 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCc1ccc(cc1)c1ccc2c(c1)[nH]c1c2CCCc2c1ccc(c2)C(=O)O
  • InChi: 1S/C28H27NO2/c1-2-3-5-18-8-10-19(11-9-18)20-12-15-24-25-7-4-6-21-16-22(28(30)31)13-14-23(21)27(25)29-26(24)17-20/h8-17,29H,2-7H2,1H3,(H,30,31)
  • InChiKey: VKNGMZDVWUHVFQ-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0043 0.0043
Trypanosoma cruzi cysteine proteinase, putative 0.0084 0.1373 0.1704
Mycobacterium tuberculosis Probable galactokinase GalK (galactose kinase) 0.0049 0.0752 0.3559
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Echinococcus multilocularis cathepsin b 0.0452 0.7916 0.7916
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0022 0.0269 0.0268
Onchocerca volvulus Putative 4.1 G protein 0.0021 0.0252 0.0595
Echinococcus granulosus tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit. C. elegans egl-36 ortholog 0.0034 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis voltage gated potassium channel 0.0034 0.0481 0.048
Onchocerca volvulus 0.0012 0.0098 0.023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus multilocularis SPRY domain containing protein 0.0021 0.0252 0.0251
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0008 0.0016 0.0015
Echinococcus granulosus short transient receptor potential channel 6 0.0034 0.0481 0.048
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0034 0.0481 0.048
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0269 0.0268
Leishmania major cysteine peptidase A (CPA) 0.0151 0.2569 0.9019
Plasmodium falciparum serine repeat antigen 9 0.0038 0.0558 0.173
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0269 0.0268
Giardia lamblia Cathepsin L-like protease 0.0038 0.0558 0.154
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0569 1 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Loa Loa (eye worm) glutathione reductase 0.0044 0.066 0.066
Echinococcus multilocularis sodium channel protein 0.0034 0.0481 0.048
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0112 0.1864 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0026 0.0331 0.0331
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus sodium leak channel non selective protein 0.0034 0.0481 0.048
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Brugia malayi neurofibromatosis homolog protein 1 0.0021 0.0252 0.0252
Echinococcus multilocularis cathepsin L cysteine protease 0.0151 0.2569 0.2568
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.1373 0.5162
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0034 0.0481 0.048
Onchocerca volvulus 0.0151 0.2569 0.6058
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0018 0.0196 0.0194
Brugia malayi cathepsin L-like cysteine proteinase 0.0038 0.0558 0.0558
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Loa Loa (eye worm) ryanodine receptor 0.0034 0.0481 0.0481
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0015 0.0147 0.0056
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0015 0.0147 0.0056
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0034 0.0481 0.048
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0034 0.0481 0.048
Echinococcus multilocularis potassium voltage gated channel protein 0.0034 0.0481 0.048
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0034 0.0481 0.048
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0021 0.0252 0.0251
Schistosoma mansoni hypothetical protein 0.0034 0.0481 0.048
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Entamoeba histolytica cysteine protease, putative 0.0151 0.2569 1
Echinococcus granulosus calcium activated potassium channel 0.0034 0.0481 0.048
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0043 0.0042
Brugia malayi cathepsin Z-like cysteine proteinase 0.0038 0.0558 0.0558
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0015 0.0138 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0038 0.0558 0.1884
Brugia malayi Cathepsin L-like precursor 0.0046 0.0691 0.0691
Echinococcus granulosus flap endonuclease 1 0.0024 0.0307 0.0306
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0196 0.0196
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Trypanosoma cruzi cysteine peptidase, putative 0.0084 0.1373 0.1704
Onchocerca volvulus 0.0022 0.0269 0.0634
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0036
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0008 0.0016 0.0015
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0022 0.0269 0.0268
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0026 0.0332 0.0332
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0196 0.021
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0043 0.0043
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0252 0.0251
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0022 0.0269 0.0268
Onchocerca volvulus 0.0022 0.0269 0.0634
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Voltage-gated calcium channel, P/Q-type, alpha subunit. C. elegans unc-2 ortholog 0.0034 0.0481 0.0481
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0038 0.0558 0.173
Brugia malayi Protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Entamoeba histolytica Flap nuclease, putative 0.0024 0.0307 0.0848
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0022 0.0269 0.0487
Toxoplasma gondii GHMP kinase, N-terminal domain-containing protein 0.0023 0.0284 0.0542
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Plasmodium vivax serine-repeat antigen (SERA) 0.0038 0.0558 0.173
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0481 0.048
Leishmania major trypanothione reductase 0.0044 0.066 0.1937
Trypanosoma brucei unspecified product 0.0018 0.0196 0.0363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Leishmania major hypothetical protein, conserved 0.0034 0.0481 0.1273
Onchocerca volvulus Cathepsin L homolog 0.0151 0.2569 0.6058
Schistosoma mansoni terminal deoxycytidyl transferase 0.0018 0.0196 0.0194
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0043 0.0043
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0022 0.0269 0.0269
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0008 0.0016 0.0015
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus multilocularis FERM domain containing protein 5 0.0021 0.0252 0.0251
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0034 0.0481 0.048
Plasmodium falciparum serine repeat antigen 5 0.0038 0.0558 0.173
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0481 0.048
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0022 0.0269 0.0268
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0015 0.0147 0.0056
Plasmodium vivax glutathione reductase, putative 0.0044 0.066 0.2148
Echinococcus granulosus transient receptor potential cation channel 0.0034 0.0481 0.048
Echinococcus multilocularis SPRY domain containing protein 0.0021 0.0252 0.0251
Echinococcus multilocularis transient receptor potential cation channel 0.0034 0.0481 0.048
Giardia lamblia Cathepsin B precursor 0.0166 0.2834 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0147 0.0149
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0043 0.0043
Trichomonas vaginalis galactokinase, putative 0.0023 0.0284 0.0904
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0038 0.0558 0.154
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0332 0.0331
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0138 0.0136
Onchocerca volvulus 0.0038 0.0558 0.1316
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0018 0.0196 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0558 0.1884
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0034 0.0481 0.048
Schistosoma mansoni cathepsin C 0.0038 0.0558 0.0557
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Onchocerca volvulus 0.0034 0.0481 0.1134
Brugia malayi ImpB/MucB/SamB family protein 0.0018 0.0196 0.0196
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Trypanosoma cruzi cysteine peptidase, putative 0.0151 0.2569 0.322
Leishmania major homoserine kinase, putative 0.0015 0.0144 0.0023
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0146
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0269 0.0268
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Echinococcus granulosus thioredoxin glutathione reductase 0.0044 0.066 0.0659
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Giardia lamblia Encystation-specific protease 0.0038 0.0558 0.154
Loa Loa (eye worm) SRC-1 0.0008 0.0016 0.0016
Echinococcus granulosus tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0558 0.1884
Brugia malayi cathepsin F-like cysteine proteinase 0.0038 0.0558 0.0558
Echinococcus granulosus TRP transient receptor potential channel 0.0034 0.0481 0.048
Giardia lamblia Cathepsin B precursor 0.0038 0.0558 0.154
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0558 0.0558
Giardia lamblia Cysteine protease 0.0038 0.0558 0.154
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0038 0.0558 0.154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Trypanosoma cruzi cysteine protease, putative 0.0084 0.1373 0.1704
Echinococcus granulosus protein tyrosine phosphatase n9 0.0022 0.0269 0.0268
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0038 0.0558 0.0558
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0166 0.2834 0.2833
Echinococcus multilocularis protein tyrosine phosphatase, non receptor type 0.0014 0.0125 0.0124
Brugia malayi hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus c src tyrosine kinase 0.0008 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.1373 0.4792
Brugia malayi galactokinase family protein 0.0023 0.0284 0.0284
Schistosoma mansoni cathepsin B (C01 family) 0.0038 0.0558 0.0557
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Toxoplasma gondii NADPH-glutathione reductase 0.0015 0.0147 0.0036
Plasmodium falciparum serine repeat antigen 6 0.0038 0.0558 0.173
Echinococcus granulosus Ezrin radixin moesin ERM 0.0021 0.0252 0.0251
Mycobacterium tuberculosis Possible D-alpha-D-heptose-7-phosphate kinase HddA 0.0015 0.0144 0.0036
Loa Loa (eye worm) GRP1 binding protein 0.0016 0.0158 0.0158
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0269 0.0268
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0036
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0481 0.048
Plasmodium vivax flap endonuclease 1, putative 0.0024 0.0307 0.0699
Echinococcus multilocularis FERM domain containing protein 5 0.0014 0.0125 0.0124
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Onchocerca volvulus Protein ultraspiracle homolog 0.0009 0.0043 0.0102
Plasmodium falciparum serine repeat antigen 8 0.0038 0.0558 0.173
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0008 0.0016 0.0015
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0008 0.0016 0.0015
Echinococcus multilocularis dna polymerase kappa 0.0018 0.0196 0.0194
Echinococcus granulosus talin 0.0012 0.0098 0.0097
Trypanosoma brucei cysteine peptidase C (CPC) 0.0166 0.2834 1
Loa Loa (eye worm) moesin 0.0021 0.0252 0.0252
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0015 0.0147 0.0149
Echinococcus granulosus potassium voltage gated channel protein 0.0034 0.0481 0.048
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0043 0.0042
Mycobacterium tuberculosis Probable dehydrogenase 0.0101 0.1665 0.8844
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0024 0.0307 0.0352
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0008 0.0016 0.0015
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0043 0.0042
Echinococcus granulosus FERM domain containing protein 5 0.0021 0.0252 0.0251
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0018 0.0196 0.0336
Onchocerca volvulus 0.0151 0.2569 0.6058
Schistosoma mansoni cathepsin F (C01 family) 0.0151 0.2569 0.2568
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Loa Loa (eye worm) voltage-dependent calcium channel 0.0034 0.0481 0.0481
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0043 0.0042
Echinococcus multilocularis transient receptor potential cation channel 0.0034 0.0481 0.048
Echinococcus multilocularis talin 2 0.0012 0.0098 0.0097
Schistosoma mansoni flap endonuclease-1 0.0022 0.0266 0.0265
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Schistosoma mansoni voltage-dependent calcium channel 0.0034 0.0481 0.048
Trichomonas vaginalis pten, drome, putative 0.0022 0.0269 0.0852
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0481 0.048
Brugia malayi cation channel family protein 0.0034 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0002
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Echinococcus multilocularis cathepsin L 0.0038 0.0558 0.0557
Giardia lamblia Cathepsin B precursor 0.0166 0.2834 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0691 0.0691
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0015 0.0147 0.0147
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0269 0.0268
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Echinococcus multilocularis FERM domain containing protein 3 0.0021 0.0252 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0043 0.0043
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0269 0.0692
Leishmania major galactokinase-like protein 0.0049 0.0752 0.2279
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0044 0.066 0.3025
Brugia malayi Ferm domain 0.0245 0.4241 0.4241
Schistosoma mansoni voltage-gated ion channel 0.0034 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.0016 0.0158 0.0157
Echinococcus multilocularis FERM central domain 0.0014 0.0125 0.0124
Trypanosoma cruzi galactokinase-like protein, putative 0.0043 0.0638 0.0771
Giardia lamblia Cathepsin B precursor 0.0038 0.0558 0.154
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Leishmania major DNA polymerase kappa, putative 0.0018 0.0196 0.0215
Echinococcus multilocularis transient receptor potential cation channel 0.0034 0.0481 0.048
Toxoplasma gondii hypothetical protein 0.0034 0.0481 0.1273
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0022 0.0269 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0009 0.003 0.0029
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0038 0.0558 0.0558
Echinococcus multilocularis galactokinase 0.0049 0.0752 0.0751
Brugia malayi hypothetical protein 0.0021 0.0252 0.0252
Schistosoma mansoni voltage-gated cation channel 0.0034 0.0481 0.048
Entamoeba histolytica cysteine proteinase, putative 0.0106 0.1754 0.6701
Echinococcus granulosus transient receptor potential gamma protein 0.0034 0.0481 0.048
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Trypanosoma cruzi homoserine kinase 0.0015 0.0144 0.0144
Brugia malayi Isocitrate dehydrogenase 0.0015 0.0138 0.0138
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Brugia malayi hypothetical protein 0.0014 0.0125 0.0125
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0046 0.0691 0.0691
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0112 0.1864 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0481 0.1608
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0038 0.0558 0.1884
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Echinococcus multilocularis potassium voltage gated channel protein 0.0034 0.0481 0.048
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0043 0.0042
Echinococcus granulosus potassium voltage gated channel protein 0.0034 0.0481 0.048
Echinococcus granulosus cathepsin L cysteine proteinase 0.0151 0.2569 0.2568
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0038 0.0558 0.0557
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0038 0.0558 0.173
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0046 0.0691 0.0691
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0043 0.0042
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0196 0.0363
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0452 0.7916 0.7916
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0022 0.0269 0.0269
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0038 0.0558 0.173
Toxoplasma gondii cathepsin CPC1 0.0038 0.0558 0.156
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0043 0.0043
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0022 0.0269 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Treponema pallidum galactokinase 0.0043 0.0638 1
Brugia malayi mevalonate kinase family protein 0.0015 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Giardia lamblia NADH oxidase lateral transfer candidate 0.0015 0.0147 0.0013
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0043 0.0043
Echinococcus granulosus cathepsin L cysteine protease 0.0084 0.1373 0.1372
Toxoplasma gondii hypothetical protein 0.0034 0.0481 0.1273
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0043 0.0043
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0009 0.0043 0.0102
Toxoplasma gondii cathepsin CPL 0.0151 0.2569 0.9019
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0034 0.0481 0.048
Mycobacterium ulcerans DNA polymerase IV 0.0018 0.0196 0.0851
Echinococcus granulosus potassium voltage gated channel protein 0.0034 0.0481 0.048
Echinococcus multilocularis isocitrate dehydrogenase 0.0015 0.0138 0.0136
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0022 0.0269 0.0268
Echinococcus granulosus FERM domain containing protein 5 0.0014 0.0125 0.0124
Brugia malayi Protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Schistosoma mansoni tyrosine kinase 0.0008 0.0016 0.0015
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0138 0.0136
Echinococcus granulosus protein tyrosine phosphatase non receptor type 0.0014 0.0125 0.0124
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0034 0.0481 0.048
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0015 0.0138 0.0136
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0034 0.0481 0.048
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0034 0.0481 0.0481
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0038 0.0558 0.1863
Echinococcus multilocularis cysteine protease 0.0151 0.2569 0.2568
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Schistosoma mansoni cathepsin S (C01 family) 0.0038 0.0558 0.0557
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0038 0.0558 0.154
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Cathepsin L-like precursor 0.0106 0.1754 0.1754
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0043 0.0042
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Tyrosine-protein kinase abl-1 0.0008 0.0016 0.0016
Echinococcus granulosus transient receptor potential cation channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0252 0.0251
Entamoeba histolytica deoxycytidyl transferase, putative 0.0018 0.0196 0.0396
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0331 0.033
Echinococcus granulosus potassium voltage gated channel protein 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Brugia malayi glutathione reductase 0.0044 0.066 0.066
Brugia malayi Cyclic-nucleotide gated cation channel 0.0034 0.0481 0.0481
Echinococcus multilocularis ryanodine receptor 44f 0.0034 0.0481 0.048
Echinococcus multilocularis ezrin 0.0014 0.0125 0.0124
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0038 0.0558 0.0557
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0034 0.0481 0.0481
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0034 0.0481 0.048
Echinococcus granulosus cathepsin L 0.0038 0.0558 0.0557
Schistosoma mansoni talin 2 0.0012 0.0098 0.0097
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Thioredoxin reductase 0.0044 0.066 0.066
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0043 0.0042
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0015 0.0138 0.0151
Schistosoma mansoni tyrosine kinase 0.0008 0.0016 0.0015
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0038 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0034 0.0481 0.048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0043 0.0043
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0038 0.0558 0.0557
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0481 0.048
Trypanosoma cruzi major cysteine proteinase, putative 0.0038 0.0558 0.067
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0569 1 1
Brugia malayi hypothetical protein 0.0007 0.0003 0.0003
Onchocerca volvulus 0.0022 0.0269 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus multilocularis voltage dependent calcium channel 0.0034 0.0481 0.048
Onchocerca volvulus 0.0106 0.1754 0.4135
Entamoeba histolytica cysteine proteinase 1, putative 0.0084 0.1373 0.5162
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0015 0.0147 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Entamoeba histolytica cysteine proteinase, putative 0.0151 0.2569 1
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0034 0.0481 0.048
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0527 0.0525
Brugia malayi Large-conductance calcium-activated potassium channel Slo-1 (KCNMA) alpha subunit. C. elegans slo-1 ortholog 0.0034 0.0481 0.0481
Trypanosoma cruzi homoserine kinase 0.0015 0.0144 0.0144
Trichomonas vaginalis flap endonuclease-1, putative 0.0024 0.0307 0.0989
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0043 0.0042
Echinococcus granulosus SPRY domain containing protein 0.0021 0.0252 0.0251
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0034 0.0481 0.048
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0146
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0151 0.2569 0.2569
Brugia malayi fibroinase precursor 0.0038 0.0558 0.0558
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0166 0.2834 0.3555
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0034 0.0481 0.048
Plasmodium vivax unspecified product 0.0038 0.0558 0.173
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Schistosoma mansoni vesicular amine transporter 0.0034 0.0481 0.048
Echinococcus multilocularis conserved hypothetical protein 0.0034 0.0481 0.048
Brugia malayi cathepsin B-like cysteine proteinase 0.0452 0.7916 0.7916
Loa Loa (eye worm) ion channel NompC 0.0034 0.0481 0.0481
Plasmodium falciparum thioredoxin reductase 0.0015 0.0147 0.004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0038 0.0558 0.0557
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0038 0.0558 0.173
Trypanosoma brucei inositol 1,4,5-trisphosphate receptor 0.0034 0.0481 0.1405
Echinococcus granulosus two pore calcium channel protein 2 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0046 0.0691 0.0691
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0558 0.0558
Brugia malayi Papain family cysteine protease containing protein 0.0038 0.0558 0.0558
Schistosoma mansoni hypothetical protein 0.0021 0.0252 0.0251
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Toxoplasma gondii transporter, cation channel family protein 0.0034 0.0481 0.1273
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.0481 0.1608
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Echinococcus multilocularis thioredoxin glutathione reductase 0.0044 0.066 0.0659
Echinococcus multilocularis 0.0022 0.0269 0.0268
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0034 0.0481 0.0481
Brugia malayi steroid hormone receptor 0.0009 0.0043 0.0043
Trypanosoma cruzi inositol 1,4,5-trisphosphate receptor, putative 0.0034 0.0481 0.0572
Echinococcus granulosus tyrosine protein kinase Src64B 0.0008 0.0016 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Giardia lamblia Cathepsin B precursor 0.0038 0.0558 0.154
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0331 0.033
Entamoeba histolytica cysteine proteinase, putative 0.0151 0.2569 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Loa Loa (eye worm) neurofibromin 2 isoform 8 0.0012 0.0098 0.0098
Echinococcus granulosus FERM C terminal PH domain 0.0009 0.003 0.0029
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0043 0.0042
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Echinococcus multilocularis H17g protein, tegumental antigen 0.0021 0.0252 0.0251
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0151 0.2569 0.2568
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0481 0.048
Echinococcus multilocularis c src tyrosine kinase 0.0008 0.0016 0.0015
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0269 0.0303
Trypanosoma cruzi mevalonate kinase, putative 0.0015 0.0144 0.0144
Giardia lamblia Cysteine protease 0.0038 0.0558 0.154
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.1373 0.5162
Brugia malayi isocitrate dehydrogenase 0.0015 0.0138 0.0138
Echinococcus multilocularis flap endonuclease 1 0.0024 0.0307 0.0306
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Onchocerca volvulus Cathepsin F homolog 0.0151 0.2569 0.6058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0084 0.1373 0.4792
Onchocerca volvulus 0.0151 0.2569 0.6058
Echinococcus granulosus ryanodine receptor 44f 0.0034 0.0481 0.048
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0038 0.0558 0.173
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0043 0.0043
Loa Loa (eye worm) protein tyrosine phosphatase 0.0022 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0038 0.0558 0.0558
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0043 0.0043
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0026 0.0331 0.0331
Trichomonas vaginalis mercuric reductase, putative 0.0015 0.0147 0.0418
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0043 0.0042
Toxoplasma gondii thioredoxin reductase 0.0044 0.066 0.1937
Echinococcus granulosus short transient receptor potential channel 6 0.0037 0.0527 0.0525
Echinococcus granulosus cathepsin l1 0.0151 0.2569 0.2568
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0014 0.0125 0.0124
Onchocerca volvulus 0.0151 0.2569 0.6058
Echinococcus granulosus SPRY domain containing protein 0.0021 0.0252 0.0251
Loa Loa (eye worm) hypothetical protein 0.0151 0.2569 0.2569
Giardia lamblia Cathepsin L-like protease 0.0038 0.0558 0.154
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Onchocerca volvulus 0.0151 0.2569 0.6058
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0038 0.0558 0.173
Onchocerca volvulus 0.0021 0.0252 0.0595
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0024 0.0307 0.063
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0022 0.0269 0.0268
Giardia lamblia DINP protein human, muc B family 0.0018 0.0196 0.0192
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Echinococcus multilocularis cysteine protease 0.0151 0.2569 0.2568
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0038 0.0558 0.154
Echinococcus granulosus protein 4.1 0.0021 0.0252 0.0251
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0043 0.0042
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0084 0.1373 0.1373
Echinococcus granulosus voltage dependent calcium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis tyrosine protein kinase Abl 0.0008 0.0016 0.0015
Brugia malayi Papain family cysteine protease containing protein 0.0084 0.1373 0.1373
Brugia malayi Cathepsin L-like precursor 0.0106 0.1754 0.1754
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0151 0.2569 1
Onchocerca volvulus Bile acid receptor homolog 0.0009 0.0043 0.0102
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus multilocularis hypothetical protein 0.0022 0.0269 0.0268
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0043 0.0042
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0008 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus radixin 0.0014 0.0125 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0166 0.2834 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0038 0.0558 0.173
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Brugia malayi FERM domain 0.0021 0.0252 0.0252
Loa Loa (eye worm) calcium channel 0.0034 0.0481 0.0481
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0024 0.0307 0.0771
Loa Loa (eye worm) hypothetical protein 0.0452 0.7916 0.7916
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0034 0.0481 0.048
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0007 0.0003 0.0002
Echinococcus multilocularis FERM, C terminal PH domain 0.0009 0.003 0.0029
Trypanosoma cruzi cysteine peptidase, putative 0.0046 0.0691 0.0838
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus granulosus tyrosine protein kinase Fyn 0.0008 0.0016 0.0015
Echinococcus granulosus transient receptor potential cation channel 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus granulosus transient receptor potential cation channel 0.0034 0.0481 0.048
Plasmodium vivax unspecified product 0.0046 0.0691 0.2275
Trypanosoma brucei protein tyrosine phosphatase 1 0.0022 0.0269 0.063
Brugia malayi ion channel NompC 0.0034 0.0481 0.0481
Brugia malayi Ryanodine Receptor TM 4-6 family protein 0.0034 0.0481 0.0481
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0043 0.0042
Onchocerca volvulus 0.0245 0.4241 1
Echinococcus granulosus hypothetical protein 0.0034 0.0481 0.048
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0196 0.021
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0038 0.0558 0.173
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0101 0.1665 0.884
Echinococcus multilocularis short transient receptor potential channel 6 0.0037 0.0527 0.0525
Mycobacterium tuberculosis Conserved hypothetical protein 0.0018 0.0196 0.0336
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Echinococcus granulosus voltage dependent calcium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0186
Echinococcus granulosus sodium channel protein 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0038 0.0558 0.0557
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0138 0.0136
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Giardia lamblia Hypothetical protein 0.0038 0.0558 0.154
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0084 0.1373 0.1704
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0151 0.2569 0.2569
Plasmodium vivax vivapain-2 0.0151 0.2569 1
Echinococcus granulosus FERM domain containing protein 3 0.0014 0.0125 0.0124
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0269 0.0268
Schistosoma mansoni hypothetical protein 0.0009 0.003 0.0029
Plasmodium falciparum thioredoxin reductase 0.0044 0.066 0.2148
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0043 0.0043
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0022 0.0269 0.0268
Brugia malayi hypothetical protein 0.0022 0.0269 0.0269
Brugia malayi voltage-dependent calcium channel 0.0034 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus multilocularis potassium voltage gated channel protein 0.0034 0.0481 0.048
Plasmodium falciparum glutathione reductase 0.0015 0.0147 0.004
Loa Loa (eye worm) ctsf protein 0.0151 0.2569 0.2569
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Onchocerca volvulus 0.0151 0.2569 0.6058
Onchocerca volvulus 0.0022 0.0269 0.0634
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0166 0.2834 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.1373 0.1372
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0331 0.033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus transient receptor potential cation channel 0.0034 0.0481 0.048
Schistosoma mansoni ryanodine receptor related 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0022 0.0269 0.0269
Onchocerca volvulus 0.0022 0.0269 0.0634
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Echinococcus multilocularis FERM and pleckstrin domain containing protein 0.0021 0.0252 0.0251
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Toxoplasma gondii preprocathepsin c precursor, putative 0.0038 0.0558 0.156
Echinococcus multilocularis two pore calcium channel protein 2 0.0034 0.0481 0.048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0038 0.0558 0.0557
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Echinococcus granulosus H17g protein tegumental antigen 0.0021 0.0252 0.0251
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0186
Echinococcus multilocularis calcium activated potassium channel 0.0034 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Brugia malayi Moesin/ezrin/radixin homolog 1 0.0021 0.0252 0.0252
Plasmodium falciparum serine repeat antigen 4 0.0038 0.0558 0.173
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0481 0.1273
Echinococcus granulosus tyrosine protein kinase Lyn 0.0008 0.0016 0.0015
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Loa Loa (eye worm) hypothetical protein 0.0106 0.1754 0.1754
Echinococcus multilocularis hyperpolarization activated cyclic 0.0034 0.0481 0.048
Echinococcus granulosus N acetylgalactosamine kinase 0.0023 0.0284 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0252 0.0252
Echinococcus granulosus cathepsin L 0.0084 0.1373 0.1372
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0034 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.0016 0.0158 0.0157
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0038 0.0558 0.173
Trypanosoma brucei DNA polymerase eta, putative 0.0018 0.0196 0.0363
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0026 0.0331 0.033
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0034 0.0481 0.048
Onchocerca volvulus Cathepsin L homolog 0.0151 0.2569 0.6058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0034 0.0481 0.048
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0043 0.0042
Echinococcus granulosus voltage gated hydrogen channel 1 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Trypanosoma cruzi cysteine proteinase, putative 0.0084 0.1373 0.1704
Schistosoma mansoni transient receptor potential channel 0.0034 0.0481 0.048
Brugia malayi cathepsin Z-like cysteine proteinase 0.0038 0.0558 0.0558
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0034 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0015 0.0147 0.004
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0011 0.0075 0.0075
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0038 0.0558 0.173
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0034 0.0481 0.0481
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0038 0.0558 0.1863
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0043 0.0042
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0015 0.0147 0.004
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0034 0.0481 0.1405
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0018 0.0196 0.059
Toxoplasma gondii GHMP kinase, putative 0.0015 0.0144 0.0023
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus granulosus potassium large conductance calcium activated 0.0034 0.0481 0.048
Echinococcus granulosus hyperpolarization activated cyclic 0.0034 0.0481 0.048
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0252 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0034 0.0481 0.048
Trypanosoma cruzi ribonuclease inhibitor, putative 0.0012 0.0098 0.0086
Brugia malayi GRP1 binding protein 0.0021 0.0252 0.0252
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Onchocerca volvulus 0.0022 0.0269 0.0634
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0037 0.0527 0.0527
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0038 0.0558 0.0557
Brugia malayi nuclear hormone receptor 0.0009 0.0043 0.0043
Onchocerca volvulus 0.0151 0.2569 0.6058
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0043 0.0042
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0008 0.0016 0.0015
Plasmodium falciparum cysteine proteinase falcipain 1 0.0084 0.1373 0.5083
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0034 0.0481 0.048
Echinococcus multilocularis potassium large conductance calcium activated 0.0034 0.0481 0.048
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0481 0.048
Echinococcus multilocularis cathepsin b 0.0452 0.7916 0.7916
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0011 0.0075 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0558 0.1884
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Trypanosoma cruzi trypanothione reductase, putative 0.0015 0.0147 0.0149
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Trichomonas vaginalis galactokinase, putative 0.0023 0.0284 0.0904
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0026 0.0332 0.0331
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0043 0.0042
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0018 0.0196 0.0194
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Plasmodium vivax thioredoxin reductase, putative 0.0044 0.066 0.2148
Toxoplasma gondii cathepsin B 0.0166 0.2834 1
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0269 0.0303
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0038 0.0558 0.173
Brugia malayi Papain family cysteine protease containing protein 0.0151 0.2569 0.2569
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0015 0.0147 1
Onchocerca volvulus 0.0022 0.0269 0.0634
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0101 0.1665 0.8844
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Loa Loa (eye worm) voltage-gated calcium channel 0.0034 0.0481 0.0481
Schistosoma mansoni tyrosine kinase 0.0008 0.0016 0.0015
Loa Loa (eye worm) fibroinase 0.0151 0.2569 0.2569
Schistosoma mansoni tyrosine kinase 0.0008 0.0016 0.0015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0452 0.7916 0.7916
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0034 0.0481 0.0481
Echinococcus multilocularis Ezrin radixin moesin ERM 0.0021 0.0252 0.0251
Echinococcus granulosus voltage gated potassium channel 0.0034 0.0481 0.048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Giardia lamblia Cathepsin B precursor 0.0038 0.0558 0.154
Mycobacterium ulcerans DNA polymerase IV 0.0018 0.0196 0.0851
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Giardia lamblia Cysteine protease 0.0038 0.0558 0.154
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0269 0.0268
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0021 0.0252 0.0251
Onchocerca volvulus 0.0021 0.0252 0.0595
Trypanosoma cruzi major cysteine proteinase, putative 0.0038 0.0558 0.067
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0034 0.0481 0.1134
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0026 0.0331 0.033
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Loa Loa (eye worm) flap endonuclease-1 0.0024 0.0307 0.0307
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0038 0.0558 0.173
Echinococcus multilocularis transient receptor potential cation channel 0.0034 0.0481 0.048
Treponema pallidum NADH oxidase 0.0015 0.0147 0.0069
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Schistosoma mansoni Band 4.1-like protein 0.0021 0.0252 0.0251
Trypanosoma brucei phosphomevalonate kinase protein, putative 0.0015 0.0144 0.0174
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0196 0.021
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit 0.0034 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Plasmodium falciparum serine repeat antigen 2 0.0038 0.0558 0.173
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Giardia lamblia Hypothetical protein 0.0038 0.0558 0.154
Echinococcus granulosus Mevalonate galactokinase 0.0015 0.0144 0.0143
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0022 0.0269 0.0268
Schistosoma mansoni transient receptor potential channel 0.0037 0.0527 0.0525
Leishmania major hypothetical protein, unknown function 0.0034 0.0481 0.1273
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0481 0.0481
Leishmania major mevalonate kinase, putative 0.0015 0.0144 0.0023
Onchocerca volvulus 0.0022 0.0269 0.0634
Echinococcus multilocularis Pleckstrin y 0.0021 0.0252 0.0251
Toxoplasma gondii transporter, cation channel family protein 0.0034 0.0481 0.1273
Giardia lamblia Cathepsin B precursor 0.0166 0.2834 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0043 0.0043
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Echinococcus granulosus merlin:moesin:ezrin:radixin 0.0021 0.0252 0.0251
Plasmodium vivax vivapain-2 0.0151 0.2569 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0569 1 1
Schistosoma mansoni transient receptor potential channel 4 0.0034 0.0481 0.048
Echinococcus multilocularis merlin:moesin:ezrin:radixin 0.0021 0.0252 0.0251
Plasmodium vivax serine-repeat antigen (SERA) 0.0038 0.0558 0.173
Leishmania major DNA polymerase eta, putative 0.0018 0.0196 0.0215
Loa Loa (eye worm) thioredoxin reductase 0.0044 0.066 0.066
Onchocerca volvulus 0.0022 0.0269 0.0634
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0038 0.0558 0.173
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0038 0.0558 0.0557
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0022 0.0269 0.0268
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Trichomonas vaginalis DNA polymerase eta, putative 0.0018 0.0196 0.059
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0034 0.0481 0.048
Schistosoma mansoni cathepsin F (C01 family) 0.0106 0.1754 0.1753
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus granulosus shaker cognate 0.0034 0.0481 0.048
Plasmodium falciparum serine repeat antigen 1 0.0038 0.0558 0.173
Leishmania major phosphomevalonate kinase protein, putative 0.0015 0.0144 0.0023
Onchocerca volvulus 0.0022 0.0269 0.0634
Entamoeba histolytica galactokinase, putative 0.0049 0.0752 0.2647
Schistosoma mansoni cathepsin F (C01 family) 0.0151 0.2569 0.2568
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus granulosus two pore calcium channel protein 1 0.0034 0.0481 0.048
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0022 0.0269 0.0303
Giardia lamblia Cysteine protease 0.0038 0.0558 0.154
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0008 0.0016 0.0015
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0151 0.2569 0.2568
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0034 0.0481 0.1273
Echinococcus granulosus cysteine protease 0.0084 0.1373 0.1372
Brugia malayi Flap endonuclease-1 0.0024 0.0307 0.0307
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0015 0.0138 0.0136
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0269 0.0268
Brugia malayi Voltage-gated calcium channel, alpha subunit 0.0034 0.0481 0.0481
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0558 0.1884
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0043 0.0042
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0043 0.0043
Plasmodium falciparum serine repeat antigen 7 0.0038 0.0558 0.173
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus multilocularis FERM domain containing protein 3 0.0014 0.0125 0.0124
Leishmania major tyrosine specific protein phosphatase, putative 0.0022 0.0269 0.0487
Loa Loa (eye worm) hypothetical protein 0.0018 0.0196 0.0196
Echinococcus multilocularis 0.0021 0.0252 0.0251
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0043 0.0043
Echinococcus granulosus galactokinase 0.0049 0.0752 0.0751
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0452 0.7916 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0146
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0038 0.0558 0.1884
Toxoplasma gondii transporter, cation channel family protein 0.0034 0.0481 0.1273
Loa Loa (eye worm) cysteine protease 0.0151 0.2569 0.2569
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Loa Loa (eye worm) hypothetical protein 0.0038 0.0558 0.0558
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Schistosoma mansoni cathepsin s 0.0046 0.0691 0.069
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0196 0.0363
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0015 0.0147 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0038 0.0558 0.1884
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0034 0.0481 0.0481
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0021 0.0252 0.0251
Echinococcus granulosus talin 2 0.0012 0.0098 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0043 0.0043
Brugia malayi cathepsin F-like cysteine proteinase 0.0046 0.0691 0.0691
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.1754 0.6149
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0481 0.048
Onchocerca volvulus 0.0022 0.0269 0.0634
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0034 0.0481 0.0481
Trypanosoma cruzi DNA polymerase eta, putative 0.0018 0.0196 0.021
Echinococcus granulosus ezrin 0.0014 0.0125 0.0124
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Schistosoma mansoni DNA polymerase eta 0.0018 0.0196 0.0194
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0034 0.0481 0.048
Echinococcus granulosus dna polymerase kappa 0.0018 0.0196 0.0194
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0101 0.1665 0.8844
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0008 0.0016 0.0015
Plasmodium vivax vivapain-1 0.0084 0.1373 0.5083
Brugia malayi Cathepsin L-like cysteine proteinase 0.0106 0.1754 0.1754
Brugia malayi Protein-tyrosine phosphatase 1 0.0026 0.0332 0.0332
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.1373 0.1372
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0015 0.0147 0.0186
Echinococcus multilocularis potassium voltage gated channel protein 0.0034 0.0481 0.048
Trypanosoma brucei homoserine kinase 0.0015 0.0144 0.0174
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0151 0.2569 0.322
Onchocerca volvulus 0.0022 0.0269 0.0634
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0015 0.0147 0.0036
Brugia malayi Talin 1 0.0012 0.0098 0.0098
Echinococcus multilocularis two pore calcium channel protein 1 0.0034 0.0481 0.048
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0022 0.0269 0.0268
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0084 0.1373 0.1372
Schistosoma mansoni hypothetical protein 0.0014 0.0125 0.0124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0022 0.0269 0.0268
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0101 0.1665 0.8844
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0022 0.0269 0.0269
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0481 0.048
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Mycobacterium tuberculosis Probable reductase 0.0101 0.1665 0.8844
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0022 0.0269 0.0692
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0106 0.1754 0.6149
Trichomonas vaginalis galactokinase, putative 0.0023 0.0284 0.0904
Echinococcus multilocularis talin 0.0012 0.0098 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0151 0.2569 0.322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0022 0.0269 0.0692
Plasmodium falciparum flap endonuclease 1 0.0024 0.0307 0.0699
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Brugia malayi hypothetical protein 0.0022 0.0269 0.0269
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0043 0.0043
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0022 0.0269 0.0268
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0022 0.0269 0.0268
Echinococcus granulosus FERM central domain 0.0014 0.0125 0.0124
Echinococcus granulosus cathepsin b 0.0452 0.7916 0.7916
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0015 0.0147 0.0036
Trypanosoma cruzi trypanothione reductase, putative 0.0044 0.066 0.0799
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus multilocularis cathepsin L cysteine protease 0.0151 0.2569 0.2568
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0018 0.0196 0.0194
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0101 0.1665 0.8844
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Echinococcus granulosus SPRY domain containing protein 0.0021 0.0252 0.0251
Schistosoma mansoni Radixin 0.0014 0.0125 0.0124
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0022 0.0269 0.0268
Echinococcus multilocularis sodium leak channel non selective protein 0.0034 0.0481 0.048
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0038 0.0558 0.1884
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0034 0.0481 0.048
Brugia malayi Ferm domain (protein4.1-ezrin-radixin-moesin) family protein 4-like 0.0014 0.0125 0.0125
Brugia malayi ecdysteroid receptor 0.0009 0.0043 0.0043
Echinococcus granulosus transient receptor potential cation channel 0.0037 0.0527 0.0525
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Echinococcus granulosus dna polymerase eta 0.0018 0.0196 0.0194
Loa Loa (eye worm) hypothetical protein 0.0007 0.0003 0.0003
Trypanosoma brucei galactokinase-like protein, putative 0.0033 0.0458 0.1321
Schistosoma mansoni 60S ribosomal protein L21 0.0034 0.0481 0.048
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0015 0.0147 0.0186
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0018 0.0196 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Loa Loa (eye worm) cathepsin B 0.0166 0.2834 0.2834
Trypanosoma cruzi cruzipain precursor, putative 0.0151 0.2569 0.322
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0034 0.0481 0.048
Trypanosoma brucei mevalonate kinase, putative 0.0015 0.0144 0.0174
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0452 0.7916 0.7916
Mycobacterium tuberculosis Probable oxidoreductase 0.0112 0.1864 1
Loa Loa (eye worm) voltage-gated potassium channel 0.0034 0.0481 0.0481
Trypanosoma brucei trypanothione reductase 0.0044 0.066 0.2059
Loa Loa (eye worm) voltage-gated potassium channel 0.0034 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Plasmodium vivax vivapain-3 0.0084 0.1373 0.5083
Schistosoma mansoni talin 0.0012 0.0098 0.0097
Brugia malayi hypothetical protein 0.0022 0.0269 0.0269
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0015 0.0147 0.0149
Giardia lamblia Protein tyrosine phosphatase 0.0022 0.0269 0.0465
Trypanosoma cruzi ribonuclease inhibitor, putative 0.0012 0.0098 0.0086
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0015 0.0147 1
Trypanosoma cruzi galactokinase, putative 0.0043 0.0638 0.0771
Brugia malayi cathepsin L-like precursor 0.0106 0.1754 0.1754
Giardia lamblia Cathepsin L precursor 0.0038 0.0558 0.154
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0034 0.0481 0.048
Echinococcus multilocularis shaker cognate 0.0034 0.0481 0.048
Schistosoma mansoni coup transcription factor 0.0009 0.0043 0.0042
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0022 0.0269 0.0268
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Entamoeba histolytica cysteine protease, putative 0.0038 0.0558 0.1863
Plasmodium falciparum glutathione reductase 0.0044 0.066 0.2148
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0038 0.0558 0.0557
Schistosoma mansoni hypothetical protein 0.0009 0.003 0.0029
Echinococcus multilocularis transient receptor potential gamma protein 0.0034 0.0481 0.048
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.1373 0.4666
Trypanosoma cruzi galactokinase, putative 0.0049 0.0752 0.0916
Trypanosoma cruzi DNA polymerase kappa, putative 0.0018 0.0196 0.021
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0024 0.0307 0.063
Brugia malayi Transient-receptor-potential like protein 0.0034 0.0481 0.0481
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0015 0.0138 0.0151
Brugia malayi hypothetical protein 0.0022 0.0269 0.0269
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0015 0.0147 0.004
Echinococcus granulosus FERM domain containing protein 3 0.0021 0.0252 0.0251
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Brugia malayi cathepsin L precursor 0.0038 0.0558 0.0558
Loa Loa (eye worm) hypothetical protein 0.0046 0.0691 0.0691
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0015 0.0138 0.0136
Schistosoma mansoni hypothetical protein 0.0021 0.0252 0.0251
Schistosoma mansoni galactokinase 0.0023 0.0284 0.0282
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0252 0.0252
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0034 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0043 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0043 0.0042
Plasmodium vivax unspecified product 0.0084 0.1373 0.5083
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Onchocerca volvulus Cathepsin L homolog 0.0038 0.0558 0.1316
Trichomonas vaginalis glutathione reductase, putative 0.0015 0.0147 0.0418
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Trypanosoma cruzi cysteine peptidase, putative 0.0151 0.2569 0.322
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus multilocularis transient receptor potential cation channel 0.0037 0.0527 0.0525
Echinococcus granulosus cathepsin b 0.0452 0.7916 0.7916
Trypanosoma cruzi cruzipain precursor, putative 0.0046 0.0691 0.0838
Onchocerca volvulus 4.1 G protein, putative homolog 0.0035 0.0491 0.1158
Echinococcus multilocularis transfer RNA-Gly 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0009 0.0043 0.0043
Onchocerca volvulus 0.0009 0.0043 0.0102
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0034 0.0481 0.0481
Plasmodium falciparum cysteine proteinase falcipain 3 0.0151 0.2569 1
Echinococcus multilocularis dna polymerase eta 0.0018 0.0196 0.0194
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0452 0.7916 0.7916
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Echinococcus granulosus tyrosine protein kinase Src42A 0.0008 0.0016 0.0015
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Echinococcus granulosus potassium voltage gated channel protein 0.0034 0.0481 0.048
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0569 1 1
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0015 0.0147 0.004
Brugia malayi olfactory channel protein osm-9 0.0037 0.0527 0.0527
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0112 0.1864 1
Schistosoma mansoni mevalonate kinase 0.0015 0.0144 0.0143
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0034 0.0481 0.0572
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0034 0.0481 0.048
Echinococcus granulosus cathepsin l1 0.0106 0.1754 0.1753
Brugia malayi protein-tyrosine-phosphatase 0.0014 0.0125 0.0125
Toxoplasma gondii cathepsin CPC2 0.0038 0.0558 0.156
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0043 0.0043
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0034 0.0481 0.048
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0034 0.0481 0.048
Schistosoma mansoni transient receptor potential channel 0.0034 0.0481 0.048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0043 0.0043
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus FERM and pleckstrin domain containing protein 0.0021 0.0252 0.0251
Trypanosoma brucei DNA polymerase IV, putative 0.0018 0.0196 0.0363
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0022 0.0269 0.0268
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.1373 0.5162
Plasmodium falciparum serine repeat antigen 3 0.0038 0.0558 0.173
Trypanosoma cruzi galactokinase, putative 0.0049 0.0752 0.0916
Schistosoma mansoni protein tyrosine phosphatase 0.0022 0.0269 0.0268
Echinococcus multilocularis radixin 0.0014 0.0125 0.0124
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0043 0.0042
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Giardia lamblia Flap structure-specific endonuclease 0.0024 0.0307 0.0608
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0038 0.0558 0.1884
Echinococcus multilocularis short transient receptor potential channel 6 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0043 0.0042
Echinococcus granulosus cathepsin l cysteine peptidase 0.0151 0.2569 0.2568
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0043 0.0042
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0034 0.0481 0.048
Schistosoma mansoni two-pore calcium channel 0.0034 0.0481 0.048
Brugia malayi cation channel family protein 0.0034 0.0481 0.0481
Loa Loa (eye worm) hypothetical protein 0.0106 0.1754 0.1754
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0015 0.0138 0.0136
Loa Loa (eye worm) isocitrate dehydrogenase 0.0015 0.0138 0.0138
Loa Loa (eye worm) galactokinase 0.0023 0.0284 0.0284
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Loa Loa (eye worm) hypothetical protein 0.0021 0.0252 0.0252
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0043 0.0042
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Echinococcus multilocularis N acetylgalactosamine kinase 0.0023 0.0284 0.0282
Brugia malayi hypothetical protein 0.0034 0.0481 0.0481
Schistosoma mansoni pcd6 interacting protein-related 0.0022 0.0269 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0022 0.0269 0.0269
Onchocerca volvulus 0.0022 0.0269 0.0634
Trypanosoma cruzi hypothetical protein 0.0012 0.0098 0.0086
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0151 0.2569 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0151 0.2569 0.9057
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0034 0.0481 0.048
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0043 0.0043
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0022 0.0269 0.0269
Schistosoma mansoni calcium-activated potassium channel 0.0034 0.0481 0.048
Loa Loa (eye worm) hypothetical protein 0.0012 0.0098 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0018 0.0196 0.0363
Schistosoma mansoni hypothetical protein 0.0009 0.003 0.0029
Giardia lamblia Cathepsin B precursor 0.0038 0.0558 0.154
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Brugia malayi Ferm domain 0.0021 0.0252 0.0252
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0043 0.0043
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0034 0.0481 0.048
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0043 0.0042
Onchocerca volvulus Transient receptor potential cation channel trpm homolog 0.0034 0.0481 0.1134
Schistosoma mansoni hypothetical protein 0.0012 0.0098 0.0097
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0015 0.0147 0.5
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0043 0.0042
Echinococcus multilocularis voltage gated potassium channel 0.0034 0.0481 0.048
Schistosoma mansoni hypothetical protein 0.0021 0.0252 0.0251
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Echinococcus granulosus Pleckstrin y 0.0021 0.0252 0.0251
Entamoeba histolytica cysteine proteinase 2 0.0084 0.1373 0.5162
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0022 0.0269 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0151 0.2569 0.9034
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0034 0.0481 0.048
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0106 0.1754 0.2186
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Schistosoma mansoni hypothetical protein 0.0007 0.0003 0.0002
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0022 0.0269 0.0268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0151 0.2569 0.9057
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0007 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0144 0.0144
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0008 0.0016 0.0015
Entamoeba histolytica cysteine protease, putative 0.0084 0.1373 0.5162
Schistosoma mansoni merlin/moesin/ezrin/radixin 0.0021 0.0252 0.0251
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0034 0.0481 0.048
Schistosoma mansoni voltage-gated potassium channel 0.0034 0.0481 0.048
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0034 0.0481 0.0481
Brugia malayi nuclear receptor NHR-88 0.0009 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Brugia malayi SRC-1 0.0008 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0014 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0022 0.0269 0.0269
Loa Loa (eye worm) hypothetical protein 0.0245 0.4241 0.4241
Loa Loa (eye worm) hypothetical protein 0.0106 0.1754 0.1754
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0022 0.0269 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0151 0.2569 0.9057
Mycobacterium ulcerans galactokinase 0.0049 0.0752 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.1373 0.4666
Echinococcus granulosus voltage gated potassium channel 0.0034 0.0481 0.048
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0034 0.0481 0.1273
Loa Loa (eye worm) hypothetical protein 0.0034 0.0481 0.0481
Entamoeba histolytica cysteine proteinase, putative 0.0084 0.1373 0.5162
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0022 0.0269 0.0268
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0043 0.0042
Brugia malayi Cathepsin L-like precursor 0.0151 0.2569 0.2569
Echinococcus multilocularis cathepsin L 0.0084 0.1373 0.1372
Trichomonas vaginalis galactokinase, putative 0.0023 0.0284 0.0904
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0038 0.0558 0.1884
Leishmania major cathepsin L-like protease 0.0151 0.2569 0.9019
Echinococcus multilocularis voltage gated hydrogen channel 1 0.0034 0.0481 0.048
Entamoeba histolytica hypothetical protein 0.0038 0.0558 0.1863
Echinococcus multilocularis Mevalonate galactokinase 0.0015 0.0144 0.0143

Activities

Activity type Activity value Assay description Source Reference
Efficacy (functional) = 0.332 % Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells in presence of 1 mM Zinc by kinase activation based reporter gene assay ChEMBL. 18783949
Efficacy (functional) = 71 % Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells in presence of 1 mM Zinc by kinase activation based reporter gene assay relative to 30 ng/mL thrombopoietin ChEMBL. 18783949

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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