Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
504 records found | Showing page 2 of 21 (records 26-50) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
| M. tuberculosis | Rv0146 | OG5_135170 | Possible S-adenosylmethionine-dependent methyltransferase |
| M. tuberculosis | Rv0153c | OG5_132308 | Phosphotyrosine protein phosphatase PTPB (protein-tyrosine-phosphatase) (PTPase) |
| M. tuberculosis | Rv0155 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic pa ... |
| M. tuberculosis | Rv0160c | OG5_132981 | PE family protein PE4 |
| M. tuberculosis | Rv0182c | OG5_179275 | Probable alternative RNA polymerase sigma factor SigG (RNA polymerase ECF type s ... |
| M. tuberculosis | Rv0183 | OG5_127037 | Possible lysophospholipase |
| M. tuberculosis | Rv0192 | OG5_204773 | Conserved hypothetical protein |
| M. tuberculosis | Rv0202c | OG5_131048 | Probable conserved transmembrane transport protein MmpL11 |
| M. tuberculosis | Rv0211 | OG5_129007 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoeno ... |
| M. tuberculosis | Rv0222 | OG5_169926 | Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0223c | OG5_137356 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0233 | OG5_126823 | Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase ... |
| M. tuberculosis | Rv0256c | OG5_237726 | PPE family protein PPE2 |
| M. tuberculosis | Rv0263c | OG5_137097 | Conserved hypothetical protein |
| M. tuberculosis | Rv0264c | OG5_138055 | Conserved hypothetical protein |
| M. tuberculosis | Rv0271c | OG5_145209 | Probable acyl-CoA dehydrogenase FadE6 |
| M. tuberculosis | Rv0286 | OG5_173655 | PPE family protein PPE4 |
| M. tuberculosis | Rv0287 | OG5_204582 | ESAT-6 like protein EsxG (conserved protein TB9.8) |
| M. tuberculosis | Rv0288 | OG5_204581 | Low molecular weight protein antigen 7 EsxH (10 kDa antigen) (CFP-7) (protein TB ... |
| M. tuberculosis | Rv0289 | OG5_237817 | ESX-3 secretion-associated protein EspG3 |
| M. tuberculosis | Rv0295c | No group | Conserved protein |
| M. tuberculosis | Rv0300 | No group | Possible antitoxin VapB2 |
| M. tuberculosis | Rv0315 | OG5_130926 | Possible beta-1,3-glucanase precursor |
| M. tuberculosis | Rv0324 | OG5_141282 | Possible transcriptional regulatory protein (possibly ArsR-family) |