Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
730 records found | Showing page 3 of 30 (records 51-75) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0157 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] ... |
| M. tuberculosis | Rv0183 | OG5_127037 | Possible lysophospholipase |
| M. tuberculosis | Rv0189c | OG5_128618 | Probable dihydroxy-acid dehydratase IlvD (dad) |
| M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase |
| M. tuberculosis | Rv0208c | OG5_127179 | Hypothetical methlytransferase (methylase) |
| M. tuberculosis | Rv0211 | OG5_129007 | Probable iron-regulated phosphoenolpyruvate carboxykinase [GTP] PckA (phosphoeno ... |
| M. tuberculosis | Rv0213c | OG5_133749 | Possible methyltransferase (methylase) |
| M. tuberculosis | Rv0220 | OG5_130169 | Probable esterase LipC |
| M. tuberculosis | Rv0222 | OG5_169926 | Probable enoyl-CoA hydratase EchA1 (enoyl hydrase) (unsaturated acyl-CoA hydrata ... |
| M. tuberculosis | Rv0223c | OG5_137356 | Probable aldehyde dehydrogenase |
| M. tuberculosis | Rv0228 | OG5_176236 | Probable integral membrane acyltransferase |
| M. tuberculosis | Rv0231 | OG5_209064 | Probable acyl-CoA dehydrogenase FadE4 |
| M. tuberculosis | Rv0233 | OG5_126823 | Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase ... |
| M. tuberculosis | Rv0234c | OG5_127004 | Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 |
| M. tuberculosis | Rv0247c | No group | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0248c | OG5_126927 | Probable succinate dehydrogenase [iron-sulfur subunit] (succinic dehydrogenase) |
| M. tuberculosis | Rv0252 | OG5_126784 | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB |
| M. tuberculosis | Rv0255c | OG5_133997 | Probable cobyric acid synthase CobQ1 |
| M. tuberculosis | Rv0260c | No group | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0270 | OG5_126609 | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |
| M. tuberculosis | Rv0271c | OG5_145209 | Probable acyl-CoA dehydrogenase FadE6 |
| M. tuberculosis | Rv0291 | OG5_149677 | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like prot ... |
| M. tuberculosis | Rv0294 | OG5_147019 | Probable trans-aconitate methyltransferase Tam |
| M. tuberculosis | Rv0303 | OG5_135402 | Probable dehydrogenase/reductase |
| M. tuberculosis | Rv0306 | OG5_146497 | Putative oxidoreductase |