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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
8243 records found | Showing page 2 of 330 (records 26-50) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
L. major | LmjF.36.2380 | OG5_129172 | sterol 24-c-methyltransferase, putative | 326 |
L. major | LmjF.32.1820 | OG5_126676 | iron superoxide dismutase, putative | 316 |
L. major | LmjF.36.1260 | OG5_127143 | fructose-1,6-bisphosphate aldolase | 316 |
L. major | LmjF.28.2280 | OG5_127113 | DNA topoisomerase ii | 316 |
L. major | LmjF.20.0100 | OG5_126776 | phosphoglycerate kinase C, glycosomal | 316 |
L. major | LmjF.33.1690 | OG5_127429 | DNA polymerase delta catalytic subunit, putative | 316 |
L. major | LmjF.18.0990 | OG5_128034 | UDP-glucose pyrophosphorylase | 316 |
L. major | LmjF.18.0090 | OG5_126880 | alpha glucosidase II subunit, putative | 316 |
L. major | LmjF.35.0030 | OG5_126685 | pyruvate kinase | 316 |
L. major | LmjF.32.1830 | OG5_126676 | iron superoxide dismutase, putative | 316 |
L. major | LmjF.26.0140 | OG5_127379 | adenine phosphoribosyltransferase | 316 |
L. major | LmjF.21.1080 | OG5_126712 | cell division protein kinase 2,cdc2-related kinase | 316 |
L. major | LmjF.05.0970 | OG5_127129 | 3-mercaptopyruvate sulfurtransferase | 316 |
L. major | LmjF.12.0530 | OG5_126980 | glucose-6-phosphate isomerase | 316 |
L. major | LmjF.35.0020 | OG5_126685 | pyruvate kinase | 316 |
L. major | LmjF.16.1540 | OG5_128177 | DNA polymerase I alpha catalytic subunit, putative | 316 |
L. major | LmjF.10.0465 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.10.0460 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.10.0480 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.34.0150 | OG5_126911 | malate dehydrogenase, putative | 311 |
L. major | LmjF.12.0280 | OG5_126750 | ornithine decarboxylase, putative | 311 |
L. major | LmjF.10.0470 | OG5_126749 | GP63, leishmanolysin | 311 |
L. major | LmjF.34.4330 | OG5_131023 | quinonoid dihydropteridine reductase | 311 |
L. major | LmjF.04.0060 | OG5_145769 | DNA topoisomerase type IB small subunit | 306 |
L. major | LmjF.31.1220 | OG5_128905 | vacuolar-type proton translocating pyrophosphatase 1, putative | 306 |