Target list

Search results for query: PLoS NTD Query 9 (M. tuberculosis persistence)

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  • Score for genes in query #508 (Murphy & Brown scores): weighted list
  • Score for genes in query #507 (Mtu genes w/ PDB structures): 5
  • Score for genes in query #509 (Hasan et al. persistence scores): weighted list

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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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2253 records found | Showing page 3 of 91 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv3334   OG5_132018   Probable transcriptional regulatory protein (probably MerR-family) 435
M. tuberculosis   Rv1168c   OG5_135481   PPE family protein PPE17 429
M. tuberculosis   Rv1221   OG5_132054   Alternative RNA polymerase sigma factor SigE 424
M. tuberculosis   Rv0752c   OG5_136059   Probable acyl-CoA dehydrogenase FadE9 422
M. tuberculosis   Rv1331   OG5_181191   Conserved hypothetical protein 420
M. tuberculosis   Rv2878c   OG5_129566   Soluble secreted antigen Mpt53 precursor 418
M. tuberculosis   Rv0082   OG5_143851   Probable oxidoreductase 418
M. tuberculosis   Rv3841   OG5_127547   Bacterioferritin BfrB 412
M. tuberculosis   Rv1954c     No group Hypothetical protein 412
M. tuberculosis   Rv0137c   OG5_126847   Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... 410
M. tuberculosis   Rv3406   OG5_129515   Probable dioxygenase 402
M. tuberculosis   Rv3616c   OG5_237581   ESX-1 secretion-associated protein A, EspA 402
M. tuberculosis   Rv3416   OG5_237579   Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster. 402
M. tuberculosis   Rv1404   OG5_160441   Probable transcriptional regulatory protein 397
M. tuberculosis   Rv3484   OG5_213861   Possible conserved protein CpsA 396
M. tuberculosis   Rv1998c   OG5_146820   Conserved protein 394
M. tuberculosis   Rv2295   OG5_230482   Conserved hypothetical protein 393
M. tuberculosis   Rv3437     No group Possible conserved transmembrane protein 391
M. tuberculosis   Rv3134c   OG5_126997   Universal stress protein family protein 389
M. tuberculosis   Rv3556c   OG5_147360   Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) 388
M. tuberculosis   Rv0886   OG5_217326   Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (fer ... 388
M. tuberculosis   Rv2359   OG5_130371   Probable zinc uptake regulation protein Zur 377
M. tuberculosis   Rv2429   OG5_165107   Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D) 376
M. tuberculosis   Rv0834c   OG5_129879   PE-PGRS family protein PE_PGRS14 376
M. tuberculosis   Rv3572     No group Unknown protein 375

Showing page 3 (records 51-75) of 91