Target list

Search results for query: PLoS NTD Query 11 (S. mansoni)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #253 (Sma EC numbers - uploaded list): 10
  • Score for genes in query #273 (Sma uploaded list of targets similar to known human targets (Berriman et al, 2009)): 10
  • Score for genes in query #254 (Orthologs of D. melanogaster genes with mutant phenotype lethal): 10
  • Score for genes in query #267 (expressed in any relevant stage (ESTs)): 10
  • Score for genes in query #272 (Sma uploaded list of targets identified by STARlite search (Berriman et al, 2009)): 10
  • Score for genes in query #263 (druggable genes inferred by sequence simiarity): 10
  • Score for genes in query #270 (Sma in Cel): 10
  • Score for genes in query #264 (expressed in adult worm (ESTs)): 3
  • Score for genes in query #257 (Growth Defect in C. elegans): 3
  • Score for genes in query #268 (Sma all proteins): 1
  • Score for genes in query #265 ( expressed in egg stage (ESTs)): 3
  • Score for genes in query #260 (Sterility in C. elegans): 3
  • Score for genes in query #262 (structural model available): 10
  • Score for genes in query #271 (Sma uploaded list of metabolic chokepoint enzymes (Berriman et al, 2009)): 10
  • Score for genes in query #255 (Orthologs of D. melanogaster genes with mutant phenotype neurophysiological defect): 10
  • Score for genes in query #258 (Larval/Adult Lethal/Arrest in C. elegans): 10
  • Score for genes in query #256 (Embryonic Lethal/Arrest in C. elegans): 10
  • Score for genes in query #261 (any essentiality evidence): 3
  • Score for genes in query #266 ( expressed in schistosomula stage (ESTs)): 3
  • Score for genes in query #259 (Morphology Defect in C. elegans): 3

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

12561 records found | Showing page 503 of 503 (records 12551-12561) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
S. mansoni   Smp_119560   OG5_186356   hypothetical protein 1
S. mansoni   Smp_028150     No group hypothetical protein 1
S. mansoni   Smp_182020   OG5_169625   hypothetical protein 1
S. mansoni   Smp_180700     No group hypothetical protein 1
S. mansoni   Smp_129880     No group hypothetical protein 1
S. mansoni   Smp_108680     No group ring-infested erythrocyte surface antigen 1
S. mansoni   Smp_155760   OG5_144737   hypothetical protein 1
S. mansoni   Smp_151360     No group hypothetical protein 1
S. mansoni   Smp_191750     No group hypothetical protein 1
S. mansoni   Smp_169220     No group hypothetical protein 1
S. mansoni   Smp_131160     No group hypothetical protein 1