Target list

Search results for query: PLoS NTD Query 5 (M. tuberculosis)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #68 (Mtb any genetic validation): 50
  • Score for genes in query #70 (Mtb dindex >=0.6): 35
  • Score for genes in query #67 (Mtb in Mle): 25
  • Score for genes in query #71 (Mtb Compd desirability >0.3): 35
  • Score for genes in query #65 (Mtb modbase): 30
  • Score for genes in query #63 (Mtb no TM domain): 20
  • Score for genes in query #69 (Mtb any essentiality evidence): 50
  • Score for genes in query #66 (Mtb not in humans): 25
  • Score for genes in query #61 (Mtb Pubmed): 35
  • Score for genes in query #62 (Mtb mwt <100kDa): 20
  • Score for genes in query #72 (Mtb assayable): 35
  • Score for genes in query #64 (Mtb PDB): 50
  • Score for genes in query #60 (Mtb enz (EC + func. Categ.)): 100
  • Score for genes in query #74 (Mtb all proteins): 1

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

2253 records found | Showing page 90 of 91 (records 2226-2250) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
M. tuberculosis   Rv3851     No group Possible membrane protein 46
M. tuberculosis   Rv3857c     No group Possible membrane protein 46
M. tuberculosis   Rv1440   OG5_237595   Probable protein-export membrane protein (translocase subunit) SecG 46
M. tuberculosis   Rv3288c     No group Putative protein UsfY 46
M. tuberculosis   Rv0181c   OG5_133132   Conserved hypothetical protein 41
M. tuberculosis   Rv0796   OG5_128670   Putative transposase for insertion sequence element IS6110 41
M. tuberculosis   Rv1084   OG5_129852   Conserved protein 41
M. tuberculosis   Rv1369c   OG5_128670   Probable transposase 41
M. tuberculosis   Rv1756c   OG5_128670   Putative transposase 41
M. tuberculosis   Rv1764   OG5_128670   Putative transposase 41
M. tuberculosis   Rv2106   OG5_128670   Probable transposase 41
M. tuberculosis   Rv2167c   OG5_128670   Probable transposase 41
M. tuberculosis   Rv2279   OG5_128670   Probable transposase 41
M. tuberculosis   Rv2355   OG5_128670   Probable transposase 41
M. tuberculosis   Rv2407   OG5_126816   Conserved hypothetical protein 41
M. tuberculosis   Rv2479c   OG5_128670   Probable transposase 41
M. tuberculosis   Rv2649   OG5_128670   Probable transposase for insertion sequence element IS6110 41
M. tuberculosis   Rv2814c   OG5_128670   Probable transposase 41
M. tuberculosis   Rv3185   OG5_128670   Probable transposase 41
M. tuberculosis   Rv3187   OG5_128670   Probable transposase 41
M. tuberculosis   Rv3272   OG5_128463   Conserved hypothetical protein 41
M. tuberculosis   Rv3326   OG5_128670   Probable transposase 41
M. tuberculosis   Rv3380c   OG5_128670   Probable transposase 41
M. tuberculosis   Rv3475   OG5_128670   Possible transposase for insertion element IS6110 [second part] 41
M. tuberculosis   Rv3239c   OG5_126664   Probable conserved transmembrane transport protein 31

Showing page 90 (records 2226-2250) of 91