Detailed information for compound 1001814

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 389.454 | Formula: C23H26F3NO
  • H donors: 1 H acceptors: 1 LogP: 7.23 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC/C(=C\CCC)/[C@H](c1ccccc1)NC(=O)c1ccc(cc1)C(F)(F)F
  • InChi: 1S/C23H26F3NO/c1-3-5-10-17(9-4-2)21(18-11-7-6-8-12-18)27-22(28)19-13-15-20(16-14-19)23(24,25)26/h6-8,10-16,21H,3-5,9H2,1-2H3,(H,27,28)/b17-10+/t21-/m1/s1
  • InChiKey: YKNPPNZBHNKTMT-AKCCUMBPSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0652 0.0652
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.008 0.0298
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0344 0.3649 0.3648
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0034 0.0032
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0028 0.0191 0.1008
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.008 0.0079
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0003 0.0003
Loa Loa (eye worm) carboxylesterase 0.0923 1 1
Brugia malayi jmjC domain containing protein 0.0015 0.0047 0.0045
Schistosoma mansoni jumonji domain containing protein 0.0057 0.0508 0.0508
Loa Loa (eye worm) carboxylesterase 0.0156 0.1589 0.1588
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0018 0.0018
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0034 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.011 0.0488
Leishmania major cytochrome p450-like protein 0.0021 0.011 0.0186
Echinococcus multilocularis caspase 3 0.0071 0.0657 0.0657
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0134 0.1347 0.8446
Entamoeba histolytica Ran family GTPase 0.0024 0.0139 0.0335
Echinococcus multilocularis dual specificity 0.0386 0.4105 0.4105
Schistosoma mansoni ran 0.0024 0.0139 0.0139
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0003 0.0001
Brugia malayi jmjC domain containing protein 0.0015 0.0047 0.0045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0168 0.0166
Onchocerca volvulus Putative endochitinase 0.0076 0.071 0.2936
Mycobacterium tuberculosis Probable reductase 0.012 0.12 0.7498
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.011 0.0186
Schistosoma mansoni hypothetical protein 0.012 0.1198 0.1198
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus caspase 2 0.0026 0.0163 0.0163
Onchocerca volvulus 0.0231 0.2414 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0156 0.1589 0.1589
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.008 0.0192
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0495 0.5307 0.5307
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0056 0.0055
Brugia malayi steroid hormone receptor 0.0011 0.0003 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.011 0.0488
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0149 0.1232
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0297 0.0721
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0297 0.054
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.008
Loa Loa (eye worm) thioredoxin reductase 0.0053 0.0458 0.0457
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.143 0.143
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0003 0.0001
Echinococcus granulosus para nitrobenzyl esterase 0.0156 0.1589 0.1589
Echinococcus granulosus caspase 0.0097 0.0941 0.0941
Echinococcus multilocularis para nitrobenzyl esterase 0.0156 0.1589 0.1589
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.5307 0.5307
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0003 0.0003
Brugia malayi Carboxylesterase family protein 0.0156 0.1589 0.1588
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.011 0.0683
Loa Loa (eye worm) hypothetical protein 0.0013 0.0018 0.0017
Trypanosoma cruzi metacaspase, putative 0.0026 0.0163 0.0317
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.011 0.0683
Brugia malayi Cell death protein 3 precursor 0.0026 0.0163 0.0162
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0003 0.0003
Onchocerca volvulus 0.012 0.1198 0.4959
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0232 0.0231
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0508 0.0508
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0163 0.0317
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.011 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0056 0.0055
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0191 0.1193
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0198 0.0198
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0089 0.0854 0.2013
Brugia malayi intermediate filament protein 0.0026 0.0168 0.0166
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0089 0.0854 0.2013
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0226 0.0471
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Schistosoma mansoni cytochrome P450 0.0021 0.011 0.011
Echinococcus granulosus mitogen activated protein kinase 15 0.0089 0.0854 0.0854
Echinococcus multilocularis thioredoxin glutathione reductase 0.0053 0.0458 0.0458
Schistosoma mansoni hypothetical protein 0.004 0.0313 0.0313
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0335 0.071
Trypanosoma brucei protein kinase, putative 0.0089 0.0854 0.2013
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Trypanosoma cruzi ion transport protein, putative 0.011 0.109 0.2594
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0012
Brugia malayi follicle stimulating hormone receptor 0.028 0.2945 0.2944
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.4095
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.011 0.0488
Leishmania major hypothetical protein, conserved 0.0015 0.0047 0.0032
Schistosoma mansoni hypothetical protein 0.0036 0.0277 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.011 0.0683
Trypanosoma brucei Metacaspase-4 0.0026 0.0163 0.0317
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.008 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0854 0.2077
Onchocerca volvulus 0.0156 0.1589 0.6582
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus BC026374 protein S09 family 0.0156 0.1589 0.1589
Toxoplasma gondii HEAT repeat-containing protein 0.0032 0.0232 0.0457
Loa Loa (eye worm) hypothetical protein 0.0065 0.0587 0.0586
Schistosoma mansoni ap endonuclease 0.0018 0.008 0.008
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0095 0.092 0.092
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0147
Loa Loa (eye worm) hypothetical protein 0.012 0.1198 0.1196
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0149 0.1232
Plasmodium falciparum MO15-related protein kinase 0.0089 0.0854 0.7125
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0089 0.0854 0.0854
Schistosoma mansoni intermediate filament proteins 0.0026 0.0168 0.0168
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0156 0.1589 1
Trypanosoma cruzi cytochrome P450, putative 0.0032 0.0226 0.0471
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.011 0.0683
Brugia malayi polk-prov protein 0.003 0.0212 0.021
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0028 0.0191 0.1193
Trypanosoma brucei metacaspase MCA2 0.0026 0.0163 0.0317
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0053 0.0458 0.2728
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.011 0.0683
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.143 0.143
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0318 0.1997
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.011 0.0488
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.011 0.0683
Leishmania major trypanothione reductase 0.0053 0.0458 0.1042
Plasmodium vivax hypothetical protein, conserved 0.012 0.1198 1
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.5307 0.5307
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0191 0.0385
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0047 0.0047
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.008 0.0191
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0458 0.1042
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0026 0.0025
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.011 0.0683
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0854 0.1922
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0138
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0003 0.0003
Echinococcus multilocularis 0.0021 0.011 0.011
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.008 0.0112
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0386 0.4105 1
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.008
Plasmodium falciparum thioredoxin reductase 0.0053 0.0458 0.3818
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi metacaspase 5, putative 0.0026 0.0163 0.0317
Schistosoma mansoni caspase-7 (C14 family) 0.0026 0.0163 0.0163
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.008 0.0079
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0258
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.008 0.066
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0003 0.0003
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0198 0.0374
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0089 0.0854 0.7125
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Echinococcus multilocularis cyclin dependent kinase 9 0.0089 0.0854 0.0854
Echinococcus granulosus GPCR family 2 0.0018 0.008 0.008
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.008 0.008
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0277 0.0277
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0003 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0003 0.0001
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0003 0.0003
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.115
Echinococcus multilocularis dna polymerase kappa 0.004 0.0318 0.0318
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.011 0.0155
Echinococcus multilocularis citrate lyase subunit beta protein 0.0028 0.0191 0.0191
Schistosoma mansoni chitinase 0.0011 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0086 0.0817 0.0817
Schistosoma mansoni serine/threonine protein kinase 0.0089 0.0854 0.0854
Trichomonas vaginalis spcc417.12 protein, putative 0.0156 0.1589 0.3869
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0047 0.0045
Onchocerca volvulus Putative endochitinase 0.0085 0.081 0.3351
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Echinococcus multilocularis GPCR, family 2 0.0018 0.008 0.008
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.011 0.0488
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.143 0.1429
Mycobacterium ulcerans chitinase/cellulase 0.0065 0.0587 0.369
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0252 0.2642 0.2641
Brugia malayi Cytochrome P450 family protein 0.0067 0.0615 0.0614
Mycobacterium ulcerans chitinase/cellulase 0.0065 0.0587 0.369
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.008 0.0192
Plasmodium vivax JmjC domain containing protein 0.0015 0.0047 0.038
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0652 0.149
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0047 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.011 0.0488
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.011 0.0186
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0047 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.008 0.0078
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0058 0.0513 0.0512
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0047 0.0045
Echinococcus multilocularis hypothetical protein 0.0086 0.0817 0.0817
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.008 0.0497
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.011 0.0488
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.011 0.0488
Toxoplasma gondii exonuclease III APE 0.0018 0.008 0.0082
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0534 0.3356
Loa Loa (eye worm) haspin protein kinase 0.0495 0.5307 0.5306
Entamoeba histolytica protein kinase domain containing protein 0.0089 0.0854 0.2077
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0024 0.0139 0.115
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0247 0.2586 0.6268
Echinococcus granulosus dual specificity 0.0386 0.4105 0.4105
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0534 0.0534
Mycobacterium tuberculosis Probable dehydrogenase 0.012 0.12 0.7498
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0163 0.0286
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0318 0.0773
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.011 0.0683
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0534 0.3356
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Loa Loa (eye worm) hypothetical protein 0.0923 1 1
Echinococcus multilocularis neuroligin 0.0156 0.1589 0.1589
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0026 0.0163 0.0163
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0018 0.0018
Brugia malayi jmjC domain containing protein 0.0057 0.0508 0.0507
Leishmania major DNA polymerase kappa, putative 0.0021 0.0104 0.0173
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Echinococcus granulosus lamin dm0 0.0026 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0277 0.0277
Onchocerca volvulus Putative endochitinase 0.0085 0.081 0.3351
Brugia malayi Pre-SET motif family protein 0.0029 0.0198 0.0197
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0534 0.0534
Loa Loa (eye worm) haspin protein kinase 0.0495 0.5307 0.5306
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0386 0.4105 0.4104
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0318 0.0699
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0003 0.0001
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.008 0.008
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0165 0.04
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0386 0.4105 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.008 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0003 0.0001
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.008 0.0655
Brugia malayi Protein kinase domain containing protein 0.0089 0.0854 0.0852
Brugia malayi endochitinase 0.0076 0.071 0.0708
Mycobacterium tuberculosis Conserved protein 0.0028 0.0191 0.1008
Brugia malayi Carboxylesterase family protein 0.0923 1 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2106 0.2105
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0854 0.1922
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0047 0.0047
Schistosoma mansoni jumonji/arid domain-containing protein 0.0057 0.0508 0.0508
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0344 0.3649 0.3649
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0003 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Plasmodium vivax thioredoxin reductase, putative 0.0053 0.0458 0.3818
Brugia malayi nuclear receptor NHR-88 0.0011 0.0003 0.0001
Echinococcus granulosus dna polymerase eta 0.0014 0.0034 0.0034
Entamoeba histolytica hypothetical protein 0.0036 0.0277 0.0672
Trypanosoma brucei metacaspase 5, putative 0.0026 0.0163 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0198 0.0198
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.011 0.0488
Schistosoma mansoni gliotactin 0.0156 0.1589 0.1589
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0058 0.0513 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) hypothetical protein 0.0059 0.0523 0.0521
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0534 0.0533
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) cytochrome P450 family protein 0.0067 0.0615 0.0614
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.4095
Trypanosoma cruzi ion transport protein, putative 0.011 0.109 0.2594
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0318 0.1997
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0318 0.0773
Plasmodium falciparum thioredoxin reductase 0.0018 0.008 0.0655
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0156 0.1589 0.1589
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0024 0.0139 0.0138
Brugia malayi hypothetical protein 0.0016 0.0053 0.0052
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0156 0.1589 0.1589
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0026 0.0165 0.04
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.179 0.4358
Onchocerca volvulus 0.012 0.1198 0.4959
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0534 0.1229
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.008 0.0112
Echinococcus multilocularis BC026374 protein (S09 family) 0.0156 0.1589 0.1589
Trichomonas vaginalis protein kinase atmrk1, putative 0.0089 0.0854 0.2077
Leishmania major cytochrome p450-like protein 0.0021 0.011 0.0186
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0232 0.0487
Schistosoma mansoni hypothetical protein 0.0021 0.011 0.011
Echinococcus granulosus potassium voltage gated channel protein 0.0095 0.092 0.092
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0003 0.0001
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0018 0.008 0.0493
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0003 0.0006
Loa Loa (eye worm) chitinase I 0.0076 0.071 0.0708
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.008 0.0191
Echinococcus multilocularis snurportin 1 0.0344 0.3649 0.3649
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.011 0.0488
Trichomonas vaginalis ran, putative 0.0024 0.0139 0.0335
Giardia lamblia DINP protein human, muc B family 0.0021 0.0104 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Schistosoma mansoni hypothetical protein 0.0131 0.131 0.131
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis caspase 2 0.0026 0.0163 0.0163
Echinococcus granulosus lysine specific demethylase 5A 0.0057 0.0508 0.0508
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Schistosoma mansoni voltage-gated potassium channel 0.0095 0.092 0.092
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0003 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0495 0.5307 0.5307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0003 0.0001
Trypanosoma brucei cytochrome P450, putative 0.0032 0.0226 0.0471
Schistosoma mansoni protein kinase 0.0089 0.0854 0.0854
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0386 0.4105 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0057 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Trypanosoma brucei hypothetical protein, conserved 0.0247 0.2586 0.6268
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0335 0.071
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.008 0.0114
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0045
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0015 0.0047 0.0047
Trypanosoma brucei trypanothione reductase 0.0053 0.0458 0.1042
Plasmodium falciparum glutathione reductase 0.0018 0.008 0.0655
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0047 0.0032
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0149 0.0282
Schistosoma mansoni hypothetical protein 0.0495 0.5307 0.5307
Mycobacterium tuberculosis Putative ferredoxin reductase 0.012 0.12 0.7498
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0163 0.0286
Brugia malayi Pre-SET motif family protein 0.0203 0.2106 0.2105
Entamoeba histolytica protein kinase, putative 0.0386 0.4105 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0198 0.0198
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0156 0.1589 1
Entamoeba histolytica hypothetical protein 0.0036 0.0277 0.0672
Toxoplasma gondii thioredoxin reductase 0.0053 0.0458 0.1013
Echinococcus multilocularis lysine specific demethylase 5A 0.0057 0.0508 0.0508
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.011 0.0488
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0149 0.0282
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0003 0.0003
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.008 0.008
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.008 0.008
Echinococcus granulosus phd:f box containing protein 0.0015 0.0047 0.0047
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0198 0.0198
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0335 0.0335
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0212 0.0437
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0089 0.0854 0.7125
Echinococcus multilocularis lamin dm0 0.0026 0.0168 0.0168
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0149 0.1232
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.008 0.066
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Loa Loa (eye worm) acetylcholinesterase 1 0.0923 1 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.008 0.0081
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0318 0.0699
Schistosoma mansoni voltage-gated potassium channel 0.0095 0.092 0.092
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0003 0.0001
Echinococcus multilocularis caspase 0.0097 0.0941 0.0941
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0452 0.045
Schistosoma mansoni caspase-7 (C14 family) 0.0097 0.0941 0.0941
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0187 0.0187
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.011 0.0186
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0198 0.0198
Leishmania major metacaspase, putative 0.0026 0.0163 0.0317
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.012 0.12 0.7498
Loa Loa (eye worm) hypothetical protein 0.0131 0.131 0.1309
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.011 0.0488
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0134 0.1347 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.008 0.0295
Loa Loa (eye worm) hypothetical protein 0.0026 0.0162 0.0161
Plasmodium falciparum metacaspase-like protein 0.0026 0.0163 0.1351
Echinococcus granulosus Glycoside hydrolase chitinase domain containing protein 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) glutathione reductase 0.0053 0.0458 0.0457
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0097 0.0941 0.0941
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0104 0.0454
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.011 0.0683
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0652 0.3972
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.016 0.1635 0.1635
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0003 0.0003
Brugia malayi glutathione reductase 0.0053 0.0458 0.0457
Echinococcus multilocularis musashi 0.0026 0.0168 0.0168
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0003 0.0001
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0032 0.0226 0.1413
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0191 0.0385
Brugia malayi Cytochrome P450 family protein 0.0032 0.0226 0.0224
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0534 0.3217
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0386 0.4105 0.4104
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.008 0.0112
Loa Loa (eye worm) hypothetical protein 0.0026 0.0168 0.0166
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.011 0.0488
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.012 0.1198 0.1196
Echinococcus multilocularis dual specificity 0.0386 0.4105 0.4105
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0003 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0226 0.0224
Leishmania major cytochrome p450-like protein 0.0032 0.0226 0.0471
Entamoeba histolytica protein kinase domain containing protein 0.0386 0.4105 1
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0095 0.092 0.0919
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.012 0.1198 0.1198
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0047 0.0047
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0034 0.0034
Brugia malayi RNA, U transporter 1 0.0092 0.0883 0.0882
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.011 0.0488
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.008 0.0192
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.008 0.0655
Plasmodium vivax SET domain protein, putative 0.0029 0.0198 0.1648
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2414 0.5878
Brugia malayi Latrophilin receptor protein 2 0.0018 0.008 0.0078
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0047 0.0032
Echinococcus multilocularis caspase 8 0.0026 0.0163 0.0163
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0003 0.0001
Echinococcus granulosus lamin 0.0026 0.0168 0.0168
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.011 0.0683
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.008 0.0078
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.008 0.008
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0156 0.1589 0.3869
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0026 0.0163 0.0286
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus acetylcholinesterase 0.0923 1 1
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Onchocerca volvulus Putative endochitinase 0.0076 0.071 0.2936
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0034 0.0033
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0923 1 1
Toxoplasma gondii hypothetical protein 0.012 0.1198 0.2835
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0003 0.0006
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0028 0.0191 0.1193
Brugia malayi Cell division protein kinase 2 0.0089 0.0854 0.0852
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0089 0.0854 0.2013
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0034 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis dual specificity 0.0386 0.4105 0.4105
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.012 0.12 0.7498
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.008 0.0001
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0258
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0018 0.008 0.0493
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0047 0.0047
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0003 0.0003
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0003 0.0001
Mycobacterium ulcerans hypothetical protein 0.0028 0.0191 0.1193
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.011 0.0683
Schistosoma mansoni neuroligin 3 (S09 family) 0.0156 0.1589 0.1589
Echinococcus granulosus caspase 8 0.0026 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0025 0.0149 0.0147
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Giardia lamblia Kinase, CMGC DYRK 0.0386 0.4105 1
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.011 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Echinococcus multilocularis acetylcholinesterase 0.0923 1 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0104 0.0173
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0277 0.0277
Schistosoma mansoni caspase-3 (C14 family) 0.0097 0.0941 0.0941
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0034 0.0034
Plasmodium falciparum metacaspase 1 0.0026 0.0163 0.1351
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0024 0.0139 0.0258
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.1386 0.1386
Plasmodium falciparum conserved protein, unknown function 0.012 0.1198 1
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0089 0.0854 0.0852
Onchocerca volvulus 0.0029 0.0198 0.0817
Schistosoma mansoni coup transcription factor 0.0011 0.0003 0.0003
Trypanosoma brucei importin beta-1 subunit, putative 0.0032 0.0232 0.0487
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0047 0.038
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0168 0.0166
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0003 0.0003
Onchocerca volvulus 0.0156 0.1589 0.6582
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0652 0.0652
Brugia malayi jmjC domain containing protein 0.0057 0.0508 0.0507
Brugia malayi jmjC domain containing protein 0.0015 0.0047 0.0045
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0003 0.0001
Brugia malayi Cytochrome P450 family protein 0.0021 0.011 0.0108
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0047 0.0045
Entamoeba histolytica chitinase, putative 0.0076 0.071 0.1726
Echinococcus granulosus importin subunit beta 1 0.0032 0.0232 0.0232
Schistosoma mansoni lamin 0.0026 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0003 0.0003
Echinococcus granulosus small conductance calcium activated potassium 0.0131 0.131 0.131
Loa Loa (eye worm) hypothetical protein 0.0026 0.0163 0.0162
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0058 0.0513 0.0512
Brugia malayi jmjC domain containing protein 0.0015 0.0047 0.0045
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0652 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.012 0.1198 0.1198
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0089 0.0854 0.2077
Echinococcus granulosus serine:threonine protein kinase NLK 0.0089 0.0854 0.0854
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0104 0.0173
Onchocerca volvulus Putative endochitinase 0.0085 0.081 0.3351
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.011 0.0488
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Brugia malayi hypothetical protein 0.0036 0.0277 0.0276
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0297 0.2472
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.011 0.0683
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0018 0.008 0.5
Brugia malayi cyclin-dependent kinase 7 homolog 0.0089 0.0854 0.0852
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0003 0.0001
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0003 0.0003
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0018 0.008 0.0493
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0089 0.0854 0.0854
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0003 0.0001
Echinococcus granulosus caspase 3 0.0071 0.0657 0.0657
Loa Loa (eye worm) cytochrome P450 0.0021 0.011 0.0108
Brugia malayi Endochitinase 0.0085 0.081 0.0808
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0248 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.008 0.0112
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0047 0.0047
Schistosoma mansoni calcium-activated potassium channel 0.0131 0.131 0.131
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0198 0.0198
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0047 0.0047
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0508 0.0507
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0335 0.279
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.008 0.0114
Echinococcus multilocularis lamin 0.0026 0.0168 0.0168
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0047 0.0047
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.008 0.008
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.008 0.0112
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.011 0.0186
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Brugia malayi endochitinase 0.0085 0.081 0.0808
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0003 0.0003
Onchocerca volvulus Glucosylceramidase homolog 0.0165 0.1692 0.7009
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.011 0.0683
Loa Loa (eye worm) hypothetical protein 0.0923 1 1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0015 0.0047 0.0047
Loa Loa (eye worm) microfilarial chitinase 0.0074 0.0687 0.0686
Schistosoma mansoni ran 0.0024 0.0139 0.0139
Echinococcus multilocularis potassium voltage gated channel protein 0.0095 0.092 0.092
Loa Loa (eye worm) hypothetical protein 0.003 0.0212 0.021
Loa Loa (eye worm) hypothetical protein 0.0029 0.0198 0.0197
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0034 0.0034
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0252 0.2642 0.2641
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0318 0.0699
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.011 0.0683
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0318 0.0699
Echinococcus granulosus acetylcholinesterase 0.0923 1 1
Brugia malayi hypothetical protein 0.0025 0.0149 0.0147
Echinococcus granulosus GTP binding nuclear protein Ran 0.0024 0.0139 0.0139
Echinococcus multilocularis carboxylesterase 5A 0.0923 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Entamoeba histolytica hypothetical protein 0.0026 0.0165 0.04
Loa Loa (eye worm) cuticular endochitinase 0.0076 0.071 0.0708
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.011 0.0488
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0318 0.0699
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0086 0.0817 0.0817
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0335 0.0813
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.4105 0.4105
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0198 0.0198
Echinococcus multilocularis acetylcholinesterase 0.0923 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0003 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0018 0.008 0.0078
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0034 0.0079
Trypanosoma cruzi metacaspase, putative 0.0026 0.0163 0.0317
Brugia malayi hypothetical protein 0.0156 0.1589 0.1588
Trichomonas vaginalis importin beta-1, putative 0.0026 0.0165 0.04
Entamoeba histolytica hypothetical protein 0.0036 0.0277 0.0672
Echinococcus granulosus serine:threonine protein kinase haspin 0.0495 0.5307 0.5307
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.008
Entamoeba histolytica cell division protein kinase 2, putative 0.0089 0.0854 0.2077
Onchocerca volvulus 0.0026 0.0168 0.0689
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0212 0.0437
Mycobacterium ulcerans hypothetical protein 0.0028 0.0191 0.1193
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.011 0.0683
Onchocerca volvulus 0.0156 0.1589 0.6582
Onchocerca volvulus 0.0026 0.0168 0.0689
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0047 0.0047
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.008 0.008
Echinococcus granulosus intermediate filament protein 0.0026 0.0168 0.0168
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0028 0.0191 0.0461
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Giardia lamblia Kinase, CAMK CAMKL 0.0089 0.0854 0.1922
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.008 0.0078
Schistosoma mansoni hypothetical protein 0.0018 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0058 0.0513 0.0512
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.008 0.0114
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0091 0.0875 0.0875
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0003 0.0003
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0047 0.0047
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0089 0.0854 0.2013
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis serine/threonine kinase, putative 0.0089 0.0854 0.2077
Plasmodium vivax importin-beta 2, putative 0.0032 0.0232 0.1929
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Echinococcus granulosus carboxylesterase 5A 0.0923 1 1
Schistosoma mansoni lamin 0.0026 0.0168 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0003 0.0001
Brugia malayi Cytochrome P450 family protein 0.0032 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.004 0.0313 0.0311
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.011 0.0488
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Mycobacterium tuberculosis Probable oxidoreductase 0.0134 0.1347 0.8446
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0163 0.1351
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0026 0.0163 0.0162
Echinococcus granulosus dna polymerase kappa 0.004 0.0318 0.0318
Schistosoma mansoni calcium-activated potassium channel 0.0124 0.124 0.124
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.011 0.0683
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0534 0.0534
Brugia malayi Carboxylesterase family protein 0.0156 0.1589 0.1588
Leishmania major serine/threonine kinase-like protein, putative 0.0089 0.0854 0.2013
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0149 0.0251
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Plasmodium vivax metacaspase 1, putative 0.0026 0.0163 0.1351
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0028 0.0191 0.0385
Schistosoma mansoni ap endonuclease 0.0018 0.008 0.008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0057 0.0508 0.0508
Echinococcus granulosus neuroligin 0.0156 0.1589 0.1589
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0003 0.0003
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.011 0.011
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0089 0.0854 0.0854
Leishmania major hypothetical protein, conserved 0.0025 0.0149 0.0282
Onchocerca volvulus 0.0156 0.1589 0.6582
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0386 0.4105 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.008 0.0114
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0313 0.0311
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.008 0.0112
Onchocerca volvulus 0.0011 0.0003 0.0006
Brugia malayi Carboxylesterase family protein 0.0156 0.1589 0.1588
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.008 0.008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0003 0.0001
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0652 0.0652
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.008 0.0655
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0156 0.1589 0.1589
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0003 0.0001
Leishmania major ion transport protein-like protein 0.011 0.109 0.2594
Schistosoma mansoni importin beta-1 0.0032 0.0232 0.0232
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0156 0.1589 0.1589
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Echinococcus multilocularis dna polymerase eta 0.0014 0.0034 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0247 0.2586 0.6268
Loa Loa (eye worm) hypothetical protein 0.0026 0.0163 0.0162
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.008 1
Loa Loa (eye worm) carboxylesterase 0.0156 0.1589 0.1588
Trichomonas vaginalis AGC family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.008 0.0112
Loa Loa (eye worm) acetyltransferase 0.0141 0.143 0.1429
Onchocerca volvulus Cell death protein 3 homolog 0.0026 0.0163 0.067
Entamoeba histolytica hypothetical protein 0.0086 0.0817 0.1987
Mycobacterium tuberculosis Carboxylesterase LipT 0.0156 0.1589 1
Leishmania major hypothetical protein, conserved 0.0247 0.2586 0.6268
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0335 0.0813
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0045
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.008 0.0081
Leishmania major GTP-binding protein, putative 0.0024 0.0139 0.0258
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0003 0.0001
Brugia malayi cytochrome P450 0.0021 0.011 0.0108
Echinococcus granulosus thioredoxin glutathione reductase 0.0053 0.0458 0.0458
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.011 0.0488
Echinococcus granulosus citrate lyase subunit beta protein 0.0028 0.0191 0.0191
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0024 0.0139 0.0139
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Loa Loa (eye worm) hypothetical protein 0.012 0.1198 0.1196
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Plasmodium falciparum importin beta, putative 0.0032 0.0232 0.1929
Trichomonas vaginalis CMGC family protein kinase 0.0089 0.0854 0.2077
Onchocerca volvulus 0.0156 0.1589 0.6582
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.008 0.0112
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.179 0.4358
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0134 0.1347 0.8446
Loa Loa (eye worm) haspin protein kinase 0.0498 0.5343 0.5343
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.4105 1
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.011 0.0683
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0003 0.0001
Loa Loa (eye worm) cytochrome P450 family protein 0.0032 0.0226 0.0224
Loa Loa (eye worm) hypothetical protein 0.0095 0.092 0.0919
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0003 0.0001
Trypanosoma cruzi metacaspase, putative 0.0026 0.0163 0.0317
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0163 0.0394
Mycobacterium ulcerans carboxylesterase, LipT 0.0156 0.1589 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.008 0.0655
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0003 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Echinococcus multilocularis importin subunit beta 1 0.0032 0.0232 0.0232
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.011 0.0683
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis glucosylceramidase, putative 0.0165 0.1692 0.412
Trypanosoma brucei metacaspase MCA3 0.0026 0.0163 0.0317
Trypanosoma brucei unspecified product 0.0034 0.0248 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi importin beta-1 subunit, putative 0.0026 0.0165 0.0323
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0149 0.0282
Loa Loa (eye worm) CYP4Cod1 0.0032 0.0226 0.0224
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0097 0.0941 0.0941
Mycobacterium tuberculosis Possible chitinase 0.0065 0.0587 0.3558
Plasmodium vivax glutathione reductase, putative 0.0053 0.0458 0.3818
Echinococcus multilocularis small conductance calcium activated potassium 0.0131 0.131 0.131
Echinococcus granulosus snurportin 1 0.0344 0.3649 0.3649
Brugia malayi ecdysteroid receptor 0.0011 0.0003 0.0001
Echinococcus granulosus dual specificity 0.0386 0.4105 0.4105
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.011 0.0186
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0003 0.0001
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0168 0.0166
Echinococcus multilocularis Glycoside hydrolase, chitinase domain containing protein 1 0.0011 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0014 0.0034 0.0033
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.011 0.0683
Echinococcus granulosus dual specificity 0.0386 0.4105 0.4105
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0001
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0089 0.0854 0.0852
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0026 0.0025
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0012
Brugia malayi nuclear hormone receptor 0.0011 0.0003 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0026 0.0163 0.0394
Loa Loa (eye worm) hypothetical protein 0.0015 0.0047 0.0045
Leishmania major importin beta-1 subunit, putative 0.0026 0.0165 0.0323
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0156 0.1589 0.1588
Brugia malayi Carboxylesterase family protein 0.0156 0.1589 0.1588
Leishmania major chitinase 0.0076 0.071 0.166
Loa Loa (eye worm) follicle stimulating hormone receptor 0.028 0.2945 0.2944
Brugia malayi Thioredoxin reductase 0.0053 0.0458 0.0457
Plasmodium falciparum glutathione reductase 0.0053 0.0458 0.3818
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.011 0.0683
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0652 0.4095
Loa Loa (eye worm) hypothetical protein 0.0065 0.0596 0.0595
Brugia malayi Importin beta-1 subunit 0.0032 0.0232 0.0231
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0003 0.0003
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0318 0.0699
Entamoeba histolytica hypothetical protein 0.0036 0.0277 0.0672
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0047 0.0032
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.008 0.0112
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.012 0.12 0.8809
Trypanosoma brucei metacaspase 0.0026 0.0163 0.0317
Brugia malayi GSG2 0.0495 0.5307 0.5306
Brugia malayi hypothetical protein 0.0495 0.5307 0.5306
Echinococcus granulosus cyclin dependent kinase 9 0.0089 0.0854 0.0854
Schistosoma mansoni acetylcholinesterase 0.0156 0.1589 0.1589
Schistosoma mansoni DNA polymerase eta 0.0014 0.0034 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0089 0.0854 0.2077
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0089 0.0854 0.2013
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.012 0.12 0.7498
Trypanosoma cruzi metacaspase, putative 0.0026 0.0163 0.0317
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0318 0.0699
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0024 0.0139 0.0227
Trichomonas vaginalis glucosylceramidase, putative 0.0252 0.2642 0.6435
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0652 0.1517
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0047 0.0047
Schistosoma mansoni serine/threonine kinase 0.0089 0.0854 0.0854

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 10 % Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 0.2 uM by fluorescence polarization assay ChEMBL. 19356928
Activity (binding) = 11 % Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 1 uM by fluorescence polarization assay ChEMBL. 19356928
Activity (binding) = 16 % Displacement of fluorescein-labeled estradiol from human recombinant ERbeta at 5 uM by fluorescence polarization assay ChEMBL. 19356928
Activity (binding) = 47 % Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 0.2 uM by fluorescence polarization assay ChEMBL. 19356928
Activity (binding) = 59 % Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 1 uM by fluorescence polarization assay ChEMBL. 19356928
Activity (binding) = 68 % Displacement of fluorescein-labeled estradiol from human recombinant ERalpha at 5 uM by fluorescence polarization assay ChEMBL. 19356928

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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