TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 264.403 | Formula: C17H28O2
H donors: 0 H acceptors: 0 LogP: 4.98 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: CCCOCCCOc1ccc(cc1)CC(C)(C)C
InChi: 1S/C17H28O2/c1-5-11-18-12-6-13-19-16-9-7-15(8-10-16)14-17(2,3)4/h7-10H,5-6,11-14H2,1-4H3
InChiKey: YFVCPZNXOVONEK-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Brugia malayi	GSG2	0.0495	0.9884	1
Loa Loa (eye worm)	microfilarial chitinase	0.008	0.1385	0.1385
Echinococcus multilocularis	ribosomal protein S6 kinase alpha 3	0.0038	0.0539	0.0546
Entamoeba histolytica	protein kinase, putative	0.0038	0.0539	0.0701
Trichomonas vaginalis	spcc417.12 protein, putative	0.0022	0.0208	0.027
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Echinococcus granulosus	ribosomal protein S6 kinase alpha 3	0.0038	0.0539	0.0546
Echinococcus granulosus	serine:threonine protein kinase haspin	0.0495	0.9884	1
Giardia lamblia	Kinase, CAMK CAMKL	0.0091	0.1619	0.0671
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0036	0.0495	0.0495
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Trichomonas vaginalis	AGC family protein kinase	0.0038	0.0539	0.0701
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0036	0.0495	0.0501
Entamoeba histolytica	serine/threonine- protein kinase 6 , putative	0.0137	0.2564	0.3334
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trypanosoma cruzi	aurora B kinase, putative	0.0137	0.2564	0.2122
Echinococcus granulosus	aurora kinase A	0.0137	0.2564	0.2594
Loa Loa (eye worm)	AGC/DMPK/GEK protein kinase	0.0038	0.0539	0.0539
Echinococcus granulosus	nervana 2	0.0064	0.1068	0.108
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Trichomonas vaginalis	AGC family protein kinase	0.0137	0.2564	0.3334
Schistosoma mansoni	serine/threonine protein kinase	0.0137	0.2564	0.2594
Echinococcus granulosus	neuroligin	0.0022	0.0208	0.021
Loa Loa (eye worm)	CMGC/DYRK/DYRK1 protein kinase	0.0102	0.1836	0.1836
Loa Loa (eye worm)	haspin protein kinase	0.0495	0.9884	0.9884
Brugia malayi	hypothetical protein	0.0022	0.0208	0.021
Brugia malayi	p70 ribosomal S6 kinase beta	0.0103	0.1854	0.1875
Giardia lamblia	Kinase, CMGC DYRK	0.0387	0.7689	1
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Echinococcus multilocularis	Protein kinase C, brain isozyme	0.0038	0.0539	0.0546
Echinococcus granulosus	nervana 2	0.0064	0.1068	0.108
Loa Loa (eye worm)	AUR protein kinase	0.0137	0.2564	0.2564
Trichomonas vaginalis	serine/threonine-protein kinase sgk, putative	0.0033	0.0424	0.0551
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Mycobacterium ulcerans	carboxylesterase, LipT	0.0022	0.0208	0.1757
Echinococcus granulosus	serine threonine protein kinase nrc	0.007	0.1183	0.1197
Loa Loa (eye worm)	AUR protein kinase	0.0137	0.2564	0.2564
Trypanosoma cruzi	dual specificity tyrosine-phosphorylation-regulated kinase 2, putative	0.0387	0.7689	1
Schistosoma mansoni	gliotactin	0.0022	0.0208	0.021
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Entamoeba histolytica	PH domain containing protein kinase, putative	0.007	0.1183	0.1539
Schistosoma mansoni	voltage-gated potassium channel	0.004	0.0563	0.057
Echinococcus granulosus	dual specificity	0.0387	0.7689	0.7779
Echinococcus multilocularis	family S9 non peptidase ue (S09 family)	0.0022	0.0208	0.021
Trichomonas vaginalis	protein kinase atmrk1, putative	0.0091	0.1619	0.2106
Entamoeba histolytica	chitinase, putative	0.0082	0.1429	0.1859
Onchocerca volvulus	Putative endochitinase	0.0082	0.1429	0.592
Onchocerca volvulus	Putative endochitinase	0.0092	0.1631	0.6758
Brugia malayi	Carboxylesterase family protein	0.0022	0.0208	0.021
Echinococcus multilocularis	Cell division cycle 2 protein kinase	0.0091	0.1619	0.1638
Entamoeba histolytica	protein kinase domain containing protein	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	NDR protein kinase	0.0038	0.0539	0.0546
Entamoeba histolytica	protein kinase domain containing protein	0.0387	0.7689	1
Echinococcus granulosus	cyclin dependent kinase 9	0.0091	0.1619	0.1638
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Trypanosoma cruzi	serine/threonine protein kinase, putative	0.0091	0.1619	0.0671
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0038	0.0539	0.0546
Loa Loa (eye worm)	carboxylesterase	0.0131	0.2444	0.2444
Plasmodium vivax	hypothetical protein, conserved	0.013	0.2414	0.9416
Onchocerca volvulus		0.0022	0.0208	0.086
Brugia malayi	Carboxylesterase family protein	0.0022	0.0208	0.021
Echinococcus granulosus	ribosomal protein s6 kinase beta 1	0.0038	0.0539	0.0546
Echinococcus granulosus	mitogen activated protein kinase 15	0.0091	0.1619	0.1638
Loa Loa (eye worm)	hypothetical protein	0.013	0.2414	0.2414
Echinococcus granulosus	sodium:potassium dependent atpase beta subunit	0.0064	0.1068	0.108
Echinococcus granulosus	serine:threonine protein kinase N2	0.0038	0.0539	0.0546
Echinococcus multilocularis	protein kinase c iota type	0.0038	0.0539	0.0546
Echinococcus multilocularis	serine:threonine protein kinase haspin	0.0495	0.9884	1
Echinococcus granulosus	Pfam-B_8186 domain containing protein	0.0085	0.1504	0.1521
Schistosoma mansoni	hypothetical protein	0.013	0.2414	0.2442
Onchocerca volvulus	Putative endochitinase	0.0092	0.1631	0.6758
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Echinococcus granulosus	protein kinase c iota type	0.0038	0.0539	0.0546
Leishmania major	mitogen-activated protein kinase, putative,map kinase-like protein	0.0091	0.1619	0.0304
Loa Loa (eye worm)	cuticular endochitinase	0.0082	0.1429	0.1429
Trichomonas vaginalis	CMGC family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	serine/threonine-protein kinase	0.007	0.1183	0.1197
Echinococcus multilocularis	serine:threonine protein kinase N2	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Entamoeba histolytica	protein kinase, putative	0.0137	0.2564	0.3334
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Echinococcus granulosus	dual specificity	0.0387	0.7689	0.7779
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	AGC family protein kinase	0.0038	0.0539	0.0701
Brugia malayi	endochitinase	0.0082	0.1429	0.1446
Trichomonas vaginalis	AGC family protein kinase	0.0137	0.2564	0.3334
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Brugia malayi	hypothetical protein	0.0495	0.9884	1
Entamoeba histolytica	hypothetical protein	0.0085	0.1504	0.1956
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Brugia malayi	Endochitinase	0.0092	0.1631	0.165
Onchocerca volvulus		0.0022	0.0208	0.086
Toxoplasma gondii	aurora kinase	0.0137	0.2564	0.1217
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	voltage-gated potassium channel	0.004	0.0563	0.057
Loa Loa (eye worm)	acetylcholinesterase 1	0.0131	0.2444	0.2444
Echinococcus granulosus	Ribosomal protein S6 kinase beta 2	0.0038	0.0539	0.0546
Plasmodium vivax	cyclin dependent kinase 7 (cdk7), putative	0.0091	0.1619	0.6317
Toxoplasma gondii	hypothetical protein	0.013	0.2414	0.096
Brugia malayi	Protein kinase domain containing protein	0.0102	0.1836	0.1858
Loa Loa (eye worm)	AGC/PDK1 protein kinase	0.0091	0.1619	0.1619
Echinococcus multilocularis	serine:threonine protein kinase NLK	0.0091	0.1619	0.1638
Loa Loa (eye worm)	AGC/PKC/ETA protein kinase	0.0038	0.0539	0.0539
Echinococcus granulosus	protein kinase c epsilon type	0.0038	0.0539	0.0546
Schistosoma mansoni	acetylcholinesterase	0.0022	0.0208	0.021
Echinococcus multilocularis	nervana 2	0.0064	0.1068	0.108
Brugia malayi	Protein kinase domain containing protein	0.0038	0.0539	0.0546
Loa Loa (eye worm)	hypothetical protein	0.0096	0.1721	0.1721
Entamoeba histolytica	protein kinase, putative	0.0103	0.1854	0.2411
Schistosoma mansoni	BC026374 protein (S09 family)	0.0022	0.0208	0.021
Loa Loa (eye worm)	carboxylesterase	0.0022	0.0208	0.0208
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	serine/threonine protein kinase	0.0091	0.1619	0.1638
Plasmodium vivax	serine/threonine protein kinase KIN, putative	0.0091	0.1619	0.6317
Entamoeba histolytica	PH domain containing protein kinase, putative	0.007	0.1183	0.1539
Echinococcus multilocularis	dual specificity	0.0102	0.1836	0.1858
Loa Loa (eye worm)	hypothetical protein	0.0096	0.1721	0.1721
Brugia malayi	Protein kinase domain containing protein	0.0103	0.1854	0.1875
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0034	0.0446	0.058
Schistosoma mansoni	hypothetical protein	0.0495	0.9884	1
Trichomonas vaginalis	AGC family protein kinase	0.0124	0.229	0.2978
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Mycobacterium ulcerans	chitinase/cellulase	0.007	0.1182	1
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0102	0.1836	0.1004
Echinococcus granulosus	serine:threonine protein kinase 12 B	0.0137	0.2564	0.2594
Loa Loa (eye worm)	chitinase I	0.0082	0.1429	0.1429
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Echinococcus multilocularis	ribosomal protein s6 kinase beta 1	0.0038	0.0539	0.0546
Brugia malayi	serine/threonine kinase 12	0.0137	0.2564	0.2594
Schistosoma mansoni	atypical protein kinase C	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Plasmodium vivax	serine/threonine protein kinase 6, putative	0.0137	0.2564	1
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	AUR protein kinase	0.0137	0.2564	0.2564
Echinococcus multilocularis	serine threonine protein kinase nrc serine threonine protein kinase gad	0.007	0.1183	0.1197
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Echinococcus multilocularis	acetylcholinesterase	0.0131	0.2444	0.2472
Brugia malayi	protein kinase C II.	0.0038	0.0539	0.0546
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Entamoeba histolytica	serine/threonine- protein kinase 6, putative	0.0137	0.2564	0.3334
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0102	0.1836	0.1004
Onchocerca volvulus	Putative endochitinase	0.0092	0.1631	0.6758
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Schistosoma mansoni	serine/threonine-protein kinase	0.007	0.1183	0.1197
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Brugia malayi	Dual-specificity tyrosine-phosphorylation regulated kinase 2	0.0387	0.7689	0.7779
Echinococcus multilocularis	Hepatocellular carcinoma associated antigen 59	0.013	0.2414	0.2442
Echinococcus multilocularis	rac serine:threonine kinase	0.007	0.1183	0.1197
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0131	0.2444	0.2472
Trichomonas vaginalis	CMGC family protein kinase	0.0091	0.1619	0.2106
Brugia malayi	Protein kinase domain containing protein	0.0038	0.0539	0.0546
Echinococcus granulosus	serine:threonine protein kinase NLK	0.0091	0.1619	0.1638
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	acetylcholinesterase	0.0131	0.2444	0.2472
Loa Loa (eye worm)	AGC/AKT protein kinase	0.0103	0.1854	0.1854
Echinococcus multilocularis	hypothetical protein	0.0085	0.1504	0.1521
Loa Loa (eye worm)	CMGC/DYRK/DYRK2 protein kinase	0.0387	0.7689	0.7689
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	serine:threonine protein kinase haspin	0.0495	0.9884	1
Brugia malayi	Carboxylesterase family protein	0.0022	0.0208	0.021
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Loa Loa (eye worm)	AGC/RSK/MSK protein kinase	0.0038	0.0539	0.0539
Plasmodium falciparum	serine/threonine protein kinase, putative	0.0137	0.2564	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus multilocularis	BC026374 protein (S09 family)	0.0022	0.0208	0.021
Loa Loa (eye worm)	AGC/NDR protein kinase	0.0038	0.0539	0.0539
Onchocerca volvulus		0.013	0.2414	1
Loa Loa (eye worm)	AGC/PKN protein kinase	0.0038	0.0539	0.0539
Echinococcus multilocularis	para nitrobenzyl esterase	0.0022	0.0208	0.021
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0036	0.0495	0.0501
Trichomonas vaginalis	CMGC family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	BC026374 protein S09 family	0.0022	0.0208	0.021
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	AGC family protein kinase	0.0137	0.2564	0.3334
Echinococcus granulosus	Cell division cycle 2 protein kinase	0.0091	0.1619	0.1638
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Giardia lamblia	Kinase, CAMK CAMKL	0.0091	0.1619	0.0671
Echinococcus multilocularis	serine:threonine protein kinase 12 B	0.0137	0.2564	0.2594
Onchocerca volvulus		0.013	0.2414	1
Echinococcus granulosus	Protein kinase C brain isozyme	0.0038	0.0539	0.0546
Trypanosoma cruzi	Mitogen-activated protein kinase 10, putative	0.0091	0.1619	0.0671
Entamoeba histolytica	protein kinase domain containing protein	0.0137	0.2564	0.3334
Trichomonas vaginalis	serine/threonine kinase, putative	0.0091	0.1619	0.2106
Echinococcus multilocularis	aurora kinase A	0.0137	0.2564	0.2594
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	CMGC/CDK/CRK7 protein kinase	0.0091	0.1619	0.1619
Entamoeba histolytica	protein kinase, putative	0.0137	0.2564	0.3334
Leishmania major	serine/threonine kinase-like protein, putative	0.0091	0.1619	0.0304
Plasmodium falciparum	RAC-beta serine/threonine protein kinase	0.007	0.1183	0.4615
Entamoeba histolytica	protein kinase, putative	0.0387	0.7689	1
Echinococcus multilocularis	dual specificity	0.0387	0.7689	0.7779
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0397	0.0397
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Entamoeba histolytica	protein kinase, putative	0.0103	0.1854	0.2411
Plasmodium falciparum	MO15-related protein kinase	0.0091	0.1619	0.6317
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	carboxylesterase	0.0022	0.0208	0.0208
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	hypothetical protein	0.0131	0.2444	0.2444
Brugia malayi	Cell division protein kinase 2	0.0091	0.1619	0.1638
Echinococcus multilocularis	dual specificity	0.0387	0.7689	0.7779
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	hypothetical protein	0.0085	0.1504	0.1521
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Giardia lamblia	Kinase, CAMK CAMKL	0.0091	0.1619	0.0671
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Loa Loa (eye worm)	AGC/RSK/P70 protein kinase	0.0103	0.1854	0.1854
Schistosoma mansoni	protein kinase	0.0137	0.2564	0.2594
Echinococcus multilocularis	dual specificity	0.0387	0.7689	0.7779
Trichomonas vaginalis	G protein-coupled receptor kinase, putative	0.0091	0.1619	0.2106
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	AGC family protein kinase	0.0137	0.2564	0.3334
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	serine/threonine kinase	0.0091	0.1619	0.1638
Echinococcus multilocularis	serine:threonine protein kinase haspin	0.0495	0.9884	1
Trypanosoma brucei	dual specificity tyrosine-phosphorylation-regulated kinase 2, putative	0.0387	0.7689	1
Echinococcus multilocularis	protein kinase c epsilon type	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Entamoeba histolytica	serine/threonine protein kinase 6, putative	0.0137	0.2564	0.3334
Echinococcus granulosus	carboxylesterase 5A	0.0131	0.2444	0.2472
Entamoeba histolytica	hypothetical protein	0.0102	0.1836	0.2388
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0208	0.0208
Trichomonas vaginalis	carboxylesterase domain containing protein, putative	0.0022	0.0208	0.027
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0036	0.0495	0.0501
Echinococcus multilocularis	neuroligin	0.0022	0.0208	0.021
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Brugia malayi	serine/threonine protein kinase 6	0.0137	0.2564	0.2594
Mycobacterium ulcerans	chitinase/cellulase	0.007	0.1182	1
Leishmania major	protein kinase, putative,dual-specificity protein kinase, putative	0.0387	0.7689	1
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Loa Loa (eye worm)	AGC/RSK/RSK protein kinase	0.0038	0.0539	0.0539
Entamoeba histolytica	protein kinase, putative	0.0102	0.1836	0.2388
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Schistosoma mansoni	serine/threonine protein kinase	0.0387	0.7689	0.7779
Trypanosoma brucei	rac serine-threonine kinase, putative	0.0103	0.1854	0.0386
Brugia malayi	Carboxylesterase family protein	0.0131	0.2444	0.2472
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Loa Loa (eye worm)	hypothetical protein	0.0131	0.2444	0.2444
Onchocerca volvulus		0.0022	0.0208	0.086
Entamoeba histolytica	protein kinase, putative	0.0102	0.1836	0.2388
Leishmania major	serine/threonine-protein kinase, putative,protein kinase, putative	0.0102	0.1836	0.065
Echinococcus multilocularis	serine threonine protein kinase	0.0038	0.0539	0.0546
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	para nitrobenzyl esterase	0.0022	0.0208	0.021
Entamoeba histolytica	protein kinase , putative	0.0137	0.2564	0.3334
Schistosoma mansoni	serine/threonine protein kinase	0.0102	0.1836	0.1858
Trypanosoma cruzi	Mitogen-activated protein kinase 10, putative	0.0091	0.1619	0.0671
Plasmodium falciparum	conserved protein, unknown function	0.013	0.2414	0.9416
Brugia malayi	Carboxylesterase family protein	0.0131	0.2444	0.2472
Schistosoma mansoni	neuroligin 3 (S09 family)	0.0022	0.0208	0.021
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Onchocerca volvulus		0.0022	0.0208	0.086
Entamoeba histolytica	protein kinase 2, putative	0.007	0.1183	0.1539
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	Hepatocellular carcinoma associated antigen 59	0.013	0.2414	0.2442
Echinococcus multilocularis	cyclin dependent kinase 9	0.0091	0.1619	0.1638
Onchocerca volvulus	Putative endochitinase	0.0082	0.1429	0.592
Echinococcus multilocularis	carboxylesterase 5A	0.0131	0.2444	0.2472
Trichomonas vaginalis	AGC family protein kinase	0.0091	0.1619	0.2106
Entamoeba histolytica	protein kinase domain containing protein	0.0102	0.1836	0.2388
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Toxoplasma gondii	cell-cycle-associated protein kinase DYRK2, putative	0.0387	0.7689	1
Brugia malayi	Hr1 repeat family protein	0.0038	0.0539	0.0546
Entamoeba histolytica	protein kinase, putative	0.0103	0.1854	0.2411
Giardia lamblia	Aurora kinase	0.0137	0.2564	0.2122
Brugia malayi	endochitinase	0.0092	0.1631	0.165
Brugia malayi	Protein kinase domain containing protein	0.0091	0.1619	0.1638
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0539	0.0539
Trypanosoma brucei	CMGC/DYRK protein kinase, putative	0.0102	0.1836	0.0357
Trypanosoma brucei	aurora B kinase	0.0137	0.2564	0.1556
Echinococcus multilocularis	nervana 2	0.0064	0.1068	0.108
Loa Loa (eye worm)	haspin protein kinase	0.0495	0.9884	0.9884
Echinococcus multilocularis	Ribosomal protein S6 kinase beta 2	0.0038	0.0539	0.0546
Echinococcus multilocularis	serine:threonine protein kinase 38	0.0038	0.0539	0.0546
Echinococcus granulosus	acetylcholinesterase	0.0131	0.2444	0.2472
Schistosoma mansoni	protein kinase	0.0091	0.1619	0.1638
Plasmodium vivax	rac-beta serine/threonine protein kinase, putative	0.007	0.1183	0.4615
Loa Loa (eye worm)	hypothetical protein	0.007	0.1182	0.1182
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0022	0.0208	0.021
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0022	0.0208	0.021
Entamoeba histolytica	cell division protein kinase 2, putative	0.0091	0.1619	0.2106
Brugia malayi	serine/threonine-protein kinase 6	0.0137	0.2564	0.2594
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	calcium:calmodulin dependent protein kinase	0.007	0.1183	0.1197
Leishmania major	protein kinase, putative	0.0137	0.2564	0.1812
Trichomonas vaginalis	CMGC family protein kinase	0.0387	0.7689	1
Brugia malayi	cyclin-dependent kinase 7 homolog	0.0091	0.1619	0.1638
Echinococcus granulosus	dual specificity	0.0387	0.7689	0.7779
Echinococcus granulosus	dual specificity	0.0102	0.1836	0.1858
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0034	0.0446	0.058
Echinococcus granulosus	family S9 non peptidase ue S09 family	0.0022	0.0208	0.021
Echinococcus granulosus	protein kinase C gamma type	0.0038	0.0539	0.0546
Trichomonas vaginalis	AGC family protein kinase	0.0103	0.1854	0.2411
Echinococcus granulosus	serine/threonine protein kinase	0.007	0.1183	0.1197
Schistosoma mansoni	serine/threonine kinase	0.0038	0.0539	0.0546
Echinococcus multilocularis	acetylcholinesterase	0.0131	0.2444	0.2472
Schistosoma mansoni	serine/threonine protein kinase	0.0038	0.0539	0.0546
Trichomonas vaginalis	CMGC family protein kinase	0.0091	0.1619	0.2106
Loa Loa (eye worm)	hypothetical protein	0.013	0.2414	0.2414
Trichomonas vaginalis	AGC family protein kinase	0.0038	0.0539	0.0701
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0022	0.0208	0.021
Echinococcus multilocularis	sodium:potassium dependent atpase beta subunit	0.0064	0.1068	0.108
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Echinococcus granulosus	Glutaredoxin protein 5	0.0064	0.1068	0.108
Echinococcus granulosus	serine:threonine protein kinase haspin	0.0495	0.9884	1
Mycobacterium tuberculosis	Possible chitinase	0.007	0.1182	1
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106
Brugia malayi	Hepatocellular carcinoma-associated antigen 59 family protein	0.013	0.2414	0.2442
Onchocerca volvulus		0.0022	0.0208	0.086
Brugia malayi	Carboxylesterase family protein	0.0022	0.0208	0.021
Echinococcus multilocularis	Glutaredoxin protein 5	0.0064	0.1068	0.108
Trichomonas vaginalis	CAMK family protein kinase	0.0091	0.1619	0.2106

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2272173

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1803977