Detailed information for compound 235503

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 373.41 | Formula: C15H11N5O3S2
  • H donors: 3 H acceptors: 4 LogP: 2.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1[nH]c2c(c1/N=N\c1ccc(cc1)S(=O)(=O)N)c1scnc1cc2
  • InChi: 1S/C15H11N5O3S2/c16-25(22,23)9-3-1-8(2-4-9)19-20-13-12-10(18-15(13)21)5-6-11-14(12)24-7-17-11/h1-7,18,21H,(H2,16,22,23)/b20-19+
  • InChiKey: JYEZPRTUGSHLCK-FMQUCBEESA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0082 0.0672 0.0735
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0465 0.0454
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0233 0.0222
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.0672 0.0735
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0233 0.0339
Loa Loa (eye worm) TYRA-2 protein 0.0082 0.0672 0.0735
Entamoeba histolytica cyclin C, putative 0.0024 0.0041 0.0045
Entamoeba histolytica chitinase, putative 0.0156 0.1475 0.2241
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0041 0.0045
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.062 0.6543 1
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus histone deacetylase 3 0.0247 0.2472 0.2464
Mycobacterium ulcerans dehydrogenase 0.0042 0.0233 0.0331
Brugia malayi Cyclin C 0.0094 0.0803 0.0866
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0238 0.026
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.062 0.6543 1
Onchocerca volvulus 0.0037 0.0181 0.0445
Echinococcus multilocularis G-protein coupled receptor, putative 0.0082 0.0672 0.0661
Loa Loa (eye worm) solute carrier family 6 member 4 0.025 0.2499 0.2732
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0042 0.0238 0.0227
Trichomonas vaginalis chitinase, putative 0.0023 0.0026 0.0022
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0238 0.026
Plasmodium vivax histone deacetylase, putative 0.0223 0.2204 0.5509
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0082 0.0672 0.0661
Toxoplasma gondii histone deacetylase HDAC4 0.0106 0.0935 0.1414
Echinococcus granulosus histone deacetylase 7 0.0223 0.2204 0.2195
Plasmodium vivax serine/threonine kinase-1, putative 0.0386 0.3991 1
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0897 0.1356
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0897 0.1356
Brugia malayi Tachykinin-like peptides receptor 99D 0.0082 0.0672 0.0723
Echinococcus multilocularis carboxylesterase 5A 0.0859 0.9147 0.9146
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0042 0.0238 0.0227
Trypanosoma brucei cdc2-related kinase 1 0.0103 0.0897 0.1356
Toxoplasma gondii histone deacetylase HDAC3 0.0247 0.2472 0.3768
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.1472 0.1609
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Echinococcus granulosus G1:S specific cyclin D1 0.0024 0.0041 0.0029
Echinococcus granulosus BC026374 protein S09 family 0.0145 0.1359 0.1349
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Schistosoma mansoni amine GPCR 0.0082 0.0672 0.0735
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0256 0.0614
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0132 0.0132
Plasmodium falciparum cyclin 1 0.0024 0.0041 0.0074
Brugia malayi cell division control protein 2 homolog 0.0103 0.0897 0.0969
Brugia malayi hypothetical protein 0.0652 0.6886 0.7525
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Echinococcus multilocularis cyclin b3 0.0066 0.0496 0.0485
Brugia malayi hypothetical protein 0.0145 0.1359 0.1475
Loa Loa (eye worm) hypothetical protein 0.0363 0.3732 0.408
Loa Loa (eye worm) hypothetical protein 0.0133 0.1225 0.1339
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Giardia lamblia Kinase, CAMK CAMKL 0.0134 0.1237 0.1877
Giardia lamblia Kinase, CMGC GSK 0.0113 0.1008 0.1525
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0377 0.3891 0.594
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0103 0.0897 0.1356
Toxoplasma gondii cyclin 4, putative 0.0024 0.0041 0.0045
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0386 0.3991 0.6093
Loa Loa (eye worm) cyclin C 0.0094 0.0803 0.0878
Brugia malayi Pre-SET motif family protein 0.003 0.0108 0.0105
Entamoeba histolytica hypothetical protein 0.0377 0.3891 0.594
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0233 0.0556
Trypanosoma brucei mitotic cyclin 0.0024 0.0041 0.0045
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0082 0.0672 0.0723
Echinococcus multilocularis BC026374 protein (S09 family) 0.0145 0.1359 0.1349
Brugia malayi hypothetical protein 0.0024 0.0041 0.0032
Loa Loa (eye worm) glycosyl hydrolase family 18 protein 0.0023 0.0026 0.0028
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0248
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0061 0.0438 0.0427
Trypanosoma cruzi histone deacetylase, putative 0.0106 0.0935 0.1414
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0134 0.1237 0.1353
Schistosoma mansoni hypothetical protein 0.0173 0.166 0.1814
Onchocerca volvulus 0.0082 0.0672 0.1852
Brugia malayi Cyclin, N-terminal domain containing protein 0.016 0.1517 0.1648
Echinococcus granulosus nAChR subunit 0.0049 0.0305 0.0294
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Onchocerca volvulus Histone deacetylase 10 homolog 0.0106 0.0935 0.2604
Echinococcus granulosus cyclin dependent kinase 0.0103 0.0897 0.0886
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0082 0.0672 0.0661
Schistosoma mansoni biogenic amine (5HT) receptor 0.0208 0.2044 0.2235
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0081 0.0662 0.0651
Schistosoma mansoni myosin xvIII 0.0082 0.0672 0.0735
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.026
Entamoeba histolytica cyclin, putative 0.0117 0.1055 0.1598
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.0672 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0897 0.0981
Loa Loa (eye worm) hypothetical protein 0.0247 0.2472 0.2703
Entamoeba histolytica hypothetical protein 0.0075 0.0596 0.0894
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0033 0.0132 0.0144
Plasmodium falciparum MO15-related protein kinase 0.0134 0.1237 0.308
Onchocerca volvulus 0.0049 0.0305 0.08
Onchocerca volvulus 0.003 0.0108 0.0234
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0081 0.0662 0.0711
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.3516 0.3844
Loa Loa (eye worm) hypothetical protein 0.0117 0.1055 0.1154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0108 0.0118
Brugia malayi Importin beta-1 subunit 0.0029 0.0096 0.0093
Trichomonas vaginalis cyclins, putative 0.0066 0.0496 0.0742
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Leishmania major UDP-galactopyranose mutase 0.0042 0.0233 0.0339
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0314 0.3198 0.3496
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.046 0.0686
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0386 0.3991 0.6093
Brugia malayi hypothetical protein 0.0213 0.2097 0.2283
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus cyclins 0.0024 0.0041 0.0029
Echinococcus multilocularis histone deacetylase 6 0.0229 0.2273 0.2264
Brugia malayi Sodium:neurotransmitter symporter family protein 0.025 0.2499 0.2723
Schistosoma mansoni amine GPCR 0.0082 0.0672 0.0735
Echinococcus granulosus cyclin G2 0.0024 0.0041 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0305 0.0321
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0388 0.4004 0.4377
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus geminin 0.0173 0.166 0.165
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0049 0.0305 0.0321
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus multilocularis snurportin 1 0.0314 0.3198 0.319
Entamoeba histolytica protein kinase domain containing protein 0.0113 0.1008 0.1525
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.1408 0.1529
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Onchocerca volvulus 0.0082 0.0672 0.1852
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0042 0.0238 0.026
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0343 0.3516 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Entamoeba histolytica protein kinase, putative 0.0113 0.1008 0.1525
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0247 0.2474 0.2465
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.062 0.6543 0.7153
Echinococcus multilocularis cyclin k 0.0024 0.0041 0.0029
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0662 0.0711
Brugia malayi hypoxia-induced factor 1 0.0156 0.1472 0.1598
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0281 0.2843 0.3108
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0343 0.3516 0.3836
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0134 0.1237 0.1877
Onchocerca volvulus 0.0082 0.0672 0.1852
Echinococcus multilocularis fmrfamide receptor 0.0082 0.0672 0.0661
Echinococcus multilocularis fmrfamide receptor 0.0082 0.0672 0.0661
Schistosoma mansoni chitinase 0.0023 0.0026 0.0028
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Echinococcus granulosus peptide allatostatin:somatostatin 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0347
Trypanosoma brucei histone deacetylase 2 0.0106 0.0935 0.1414
Schistosoma mansoni hypothetical protein 0.0082 0.0672 0.0735
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0026 0.0022
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0042 0.0233 0.0331
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.3991 0.4363
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.0672 0.0661
Schistosoma mansoni protein kinase 0.0092 0.0783 0.0856
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0937 1 1
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0096 0.0085
Brugia malayi Carboxylesterase family protein 0.0145 0.1359 0.1475
Plasmodium vivax glycogen synthase kinase 3, putative 0.0113 0.1008 0.2503
Onchocerca volvulus 0.0081 0.0662 0.1821
Brugia malayi Endochitinase 0.0175 0.168 0.1826
Echinococcus multilocularis g protein coupled receptor 0.0082 0.0672 0.0661
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0061 0.0438 0.0427
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0238 0.026
Echinococcus multilocularis nischarin 0.0218 0.2153 0.2144
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1237 0.1877
Brugia malayi Carboxylesterase family protein 0.0145 0.1359 0.1475
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0145 0.1359 0.1349
Trichomonas vaginalis CK1 family protein kinase 0.0092 0.0783 0.1182
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0042 0.0238 0.0227
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0081 0.0662 0.0651
Onchocerca volvulus 0.0081 0.0662 0.1821
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Onchocerca volvulus 0.0082 0.0672 0.1852
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0113 0.1008 0.1525
Brugia malayi Serotonin receptor 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Leishmania major protein kinase, putative 0.0028 0.0078 0.0101
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0596 0.0585
Loa Loa (eye worm) hypothetical protein 0.0244 0.2439 0.2667
Trypanosoma cruzi histone deacetylase 1, putative 0.0247 0.2472 0.3768
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni nAChR subunit 0.0033 0.0132 0.0144
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0088 0.0737 0.0806
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0386 0.3991 0.6093
Loa Loa (eye worm) hypothetical protein 0.0363 0.3732 0.408
Trichomonas vaginalis cyclin B, putative 0.0024 0.0041 0.0045
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0033 0.0132 0.012
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0012 0.0013
Leishmania major mitotic cyclin, putative 0.0024 0.0041 0.0045
Echinococcus granulosus protein kinase shaggy 0.0113 0.1008 0.0997
Onchocerca volvulus Putative endochitinase 0.0175 0.168 0.474
Schistosoma mansoni neuropeptide receptor 0.0082 0.0672 0.0735
Echinococcus granulosus serine:threonine protein kinase haspin 0.0652 0.6886 0.6882
Brugia malayi cyclin fold protein 1 variant b 0.0024 0.0041 0.0032
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0238 0.0227
Echinococcus multilocularis cyclin B3 1 0.0066 0.0496 0.0485
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0041 0.0045
Schistosoma mansoni acetylcholine receptor subunit beta 0.0033 0.0132 0.0144
Schistosoma mansoni acetylcholinesterase 0.0145 0.1359 0.1486
Echinococcus granulosus single minded 2 0.0037 0.0181 0.017
Giardia lamblia Hypothetical protein 0.0066 0.0496 0.0742
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0096 0.013
Trypanosoma cruzi casein kinase, putative 0.0092 0.0783 0.1182
Echinococcus granulosus carboxylesterase 5A 0.0859 0.9147 0.9146
Loa Loa (eye worm) hypothetical protein 0.0106 0.0935 0.1022
Trypanosoma brucei histone deacetylase, putative 0.0223 0.2204 0.3357
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.1408 0.1398
Echinococcus multilocularis hypothetical protein 0.0119 0.1078 0.1067
Entamoeba histolytica hypothetical protein 0.0119 0.1078 0.1632
Leishmania major casein kinase, putative 0.0092 0.0783 0.1182
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0145 0.1359 0.1486
Trichomonas vaginalis cyclins, putative 0.0024 0.0041 0.0045
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0082 0.0672 0.0723
Echinococcus granulosus 7TM GPCR rhodopsin 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0208 0.2044 0.2235
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0033 0.0132 0.012
Echinococcus granulosus dual specificity 0.062 0.6543 0.6539
Leishmania major chitinase 0.0156 0.1475 0.2241
Loa Loa (eye worm) microfilarial chitinase 0.0152 0.143 0.1563
Trypanosoma cruzi mitotic cyclin, putative 0.0024 0.0041 0.0045
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0248
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Brugia malayi hypothetical protein 0.0042 0.0233 0.0242
Entamoeba histolytica hypothetical protein 0.0075 0.0596 0.0894
Entamoeba histolytica cyclin family protein 0.0066 0.0496 0.0742
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0094 0.0798 0.0872
Onchocerca volvulus 0.0033 0.0132 0.0304
Trypanosoma cruzi UDP-galactopyranose mutase 0.0042 0.0233 0.0339
Schistosoma mansoni histone deacetylase 4 5 0.0223 0.2204 0.241
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0145 0.1359 0.1486
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0386 0.3991 0.6093
Echinococcus multilocularis serotonin receptor 0.0208 0.2044 0.2035
Loa Loa (eye worm) hypothetical protein 0.0859 0.9147 1
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0108 0.0118
Schistosoma mansoni cyclin G 0.0024 0.0041 0.0045
Schistosoma mansoni acetylcholine receptor-related 0.0033 0.0132 0.0144
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0024 0.0041 0.0045
Echinococcus granulosus casein kinase I delta 0.0092 0.0783 0.0773
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Loa Loa (eye worm) ACC-1 protein 0.0081 0.0662 0.0723
Schistosoma mansoni histone deacetylase 1 2 3 0.0106 0.0935 0.1022
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0108 0.0096
Echinococcus granulosus cyclin t1 0.0024 0.0041 0.0029
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0238 0.0227
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0082 0.0672 0.0661
Schistosoma mansoni histamine h1 receptor 0.0082 0.0672 0.0735
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0063 0.0465 0.0509
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0238 0.026
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0324 0.0354
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0134 0.1237 0.1227
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Trypanosoma cruzi CYC2-like cyclin, putative 0.0117 0.1055 0.1598
Plasmodium falciparum protein serine/threonine kinase-1 0.0386 0.3991 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0145 0.1359 0.2063
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0343 0.3516 0.3508
Echinococcus multilocularis neuropeptide s receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0116 0.1045 0.1142
Loa Loa (eye worm) hypothetical protein 0.025 0.2499 0.2732
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0134 0.1237 0.1877
Plasmodium falciparum transporter, putative 0.0042 0.0238 0.0569
Loa Loa (eye worm) acetylcholine receptor protein 0.0033 0.0132 0.0144
Mycobacterium ulcerans chitinase/cellulase 0.0133 0.1225 0.1921
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0118
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni neuroligin 3 (S09 family) 0.0145 0.1359 0.1486
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.046 0.0503
Onchocerca volvulus 0.0081 0.0662 0.1821
Toxoplasma gondii cyclin dependent kinase binding protein 0.0024 0.0041 0.0045
Trichomonas vaginalis serine/threonine kinase, putative 0.0134 0.1237 0.1877
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0113 0.1008 0.1102
Loa Loa (eye worm) hypothetical protein 0.0372 0.3831 0.4189
Schistosoma mansoni single-minded 0.005 0.0324 0.0354
Onchocerca volvulus Putative nachr subunit 0.0081 0.0662 0.1821
Brugia malayi Cyclin, N-terminal domain containing protein 0.0117 0.1055 0.1143
Entamoeba histolytica cyclin, domain containing protein 0.0024 0.0041 0.0045
Echinococcus granulosus nischarin 0.0218 0.2153 0.2144
Echinococcus multilocularis cyclin A3 4 0.0024 0.0041 0.0029
Brugia malayi neuropeptide F receptor 0.0082 0.0672 0.0723
Plasmodium falciparum protein kinase 5 0.0103 0.0897 0.2225
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0798 0.0872
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0465 0.0704
Onchocerca volvulus 0.0082 0.0672 0.1852
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.0897 0.1356
Echinococcus multilocularis g protein coupled receptor 0.0082 0.0672 0.0661
Plasmodium falciparum chitinase 0.0023 0.0026 0.0036
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0238 0.026
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0113 0.1008 0.1102
Echinococcus multilocularis G1:S specific cyclin D1 0.0024 0.0041 0.0029
Leishmania major protein kinase, putative 0.0028 0.0078 0.0101
Loa Loa (eye worm) LGC-31 protein 0.0081 0.0662 0.0723
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0897 0.0886
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0113 0.1008 0.1102
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0042 0.0233 0.0222
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Trichomonas vaginalis cyclin B3, putative 0.0024 0.0041 0.0045
Onchocerca volvulus 0.0042 0.0238 0.0608
Echinococcus granulosus cyclin G2 0.0024 0.0041 0.0029
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi G-protein coupled receptor 0.0082 0.0672 0.0723
Onchocerca volvulus 0.0049 0.0305 0.08
Echinococcus multilocularis lysine specific demethylase 5A 0.0061 0.0438 0.0427
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0264 0.2658 0.2906
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0103 0.0897 0.0981
Leishmania major protein kinase, putative 0.0386 0.3991 0.6093
Entamoeba histolytica protein kinase, putative 0.062 0.6543 1
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0119 0.1078 0.1067
Echinococcus granulosus dual specificity 0.0377 0.3891 0.3884
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Echinococcus granulosus cyclin B 0.0117 0.1055 0.1045
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Toxoplasma gondii hypothetical protein 0.0042 0.0238 0.0347
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0081 0.0662 0.0711
Echinococcus granulosus hypothetical protein 0.0082 0.0672 0.0661
Entamoeba histolytica hypothetical protein 0.0075 0.0596 0.0894
Echinococcus granulosus 7tm_1 domain containing protein 0.0082 0.0672 0.0661
Brugia malayi hypothetical protein 0.0075 0.0596 0.0639
Echinococcus multilocularis cyclin y 0.0024 0.0041 0.0029
Echinococcus multilocularis histone deacetylase 6 0.0223 0.2204 0.2195
Loa Loa (eye worm) haspin protein kinase 0.0667 0.7045 0.7702
Trypanosoma cruzi histone deacetylase, putative 0.0223 0.2204 0.3357
Loa Loa (eye worm) haspin protein kinase 0.0652 0.6886 0.7528
Echinococcus granulosus histone deacetylase 6 0.0223 0.2204 0.2195
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.006 0.0121
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0081 0.0662 0.0651
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0256 0.0374
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0134 0.1237 0.1227
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0082 0.0672 0.0735
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0092 0.0783 0.0856
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0127 0.1156 0.1264
Echinococcus multilocularis neuroligin 0.0145 0.1359 0.1349
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.046 0.0695
Echinococcus granulosus biogenic amine 5HT receptor 0.0208 0.2044 0.2035
Echinococcus multilocularis survival motor neuron protein 1 0.0244 0.2439 0.2431
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1008 0.1525
Echinococcus granulosus cyclin dependent kinase 5 0.0103 0.0897 0.0886
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0041 0.0045
Echinococcus multilocularis protein kinase shaggy 0.0113 0.1008 0.0997
Brugia malayi hypothetical protein 0.0042 0.0238 0.0248
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Loa Loa (eye worm) carboxylesterase 0.0145 0.1359 0.1486
Plasmodium falciparum conserved protein, unknown function 0.0247 0.2474 0.6187
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0095 0.0084
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0103 0.0897 0.1356
Trypanosoma cruzi cyclin, putative 0.0117 0.1055 0.1598
Trichomonas vaginalis cyclins, putative 0.0117 0.1055 0.1598
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0082 0.0672 0.0661
Toxoplasma gondii histone deacetylase HDAC1 0.0223 0.2204 0.3357
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0033 0.0132 0.0144
Schistosoma mansoni opsin-like receptor 0.0082 0.0672 0.0735
Entamoeba histolytica hypothetical protein 0.0075 0.0596 0.0894
Loa Loa (eye worm) hypothetical protein 0.025 0.2499 0.2732
Loa Loa (eye worm) histone deacetylase 0.0223 0.2204 0.241
Entamoeba histolytica hypothetical protein 0.0065 0.0489 0.0732
Onchocerca volvulus 0.0078 0.0624 0.1713
Onchocerca volvulus 0.0081 0.0662 0.1821
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0033 0.0132 0.0132
Onchocerca volvulus 0.0145 0.1359 0.382
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0386 0.3991 0.4363
Plasmodium vivax cyclin 4, putative 0.0024 0.0041 0.0074
Echinococcus granulosus histone deacetylase 1 0.0247 0.2472 0.2464
Schistosoma mansoni hypothetical protein 0.0173 0.166 0.1814
Brugia malayi Protein kinase domain containing protein 0.0103 0.0897 0.0969
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0028
Onchocerca volvulus Putative endochitinase 0.0175 0.168 0.474
Onchocerca volvulus 0.0145 0.1359 0.382
Leishmania major serine/threonine kinase-like protein, putative 0.0134 0.1237 0.1877
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0096 0.013
Plasmodium falciparum importin beta, putative 0.0029 0.0096 0.0213
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0033 0.0132 0.012
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.0672 0.0661
Schistosoma mansoni gliotactin 0.0145 0.1359 0.1486
Brugia malayi Cyclin, N-terminal domain containing protein 0.0181 0.1749 0.1902
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Onchocerca volvulus 0.0082 0.0672 0.1852
Schistosoma mansoni cyclins 0.0066 0.0496 0.0542
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.046 0.0695
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) haspin protein kinase 0.0652 0.6886 0.7528
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0041 0.0074
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Echinococcus granulosus neuropeptides capa receptor 0.0082 0.0672 0.0661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Echinococcus granulosus histone deacetylase 6 0.0229 0.2273 0.2264
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2472 0.3768
Mycobacterium ulcerans monoamine oxidase 0.0042 0.0233 0.0331
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0042 0.0238 0.026
Brugia malayi Cell division protein kinase 2 0.0134 0.1237 0.1342
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0248
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0897 0.1356
Schistosoma mansoni hypothetical protein 0.0652 0.6886 0.7528
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Echinococcus multilocularis dro:myosuppressin receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Entamoeba histolytica protein kinase domain containing protein 0.0061 0.0441 0.0657
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0078 0.0101
Echinococcus granulosus casein kinase I delta 0.0092 0.0783 0.0773
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0024 0.0041 0.0074
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Echinococcus multilocularis glycine receptor subunit beta 0.0081 0.0662 0.0651
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.046 0.0695
Brugia malayi AKH receptor 0.0082 0.0672 0.0723
Trichomonas vaginalis cyclin D, putative 0.0024 0.0041 0.0045
Mycobacterium ulcerans oxidoreductase 0.0042 0.0233 0.0331
Brugia malayi GnHR receptor homolog 0.0082 0.0672 0.0723
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Onchocerca volvulus 0.0082 0.0672 0.1852
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0042 0.0233 0.0255
Brugia malayi hypothetical protein 0.0023 0.0026 0.0016
Toxoplasma gondii hypothetical protein 0.0247 0.2474 0.377
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0024 0.0041 0.0045
Onchocerca volvulus 0.0081 0.0662 0.1821
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Entamoeba histolytica protein kinase domain containing protein 0.0113 0.1008 0.1525
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0024 0.0041 0.0045
Echinococcus granulosus importin subunit beta 1 0.0029 0.0096 0.0085
Echinococcus multilocularis casein kinase I alpha 0.0092 0.0783 0.0773
Echinococcus multilocularis histone deacetylase 0.0223 0.2204 0.2195
Schistosoma mansoni opsin-like receptor 0.0082 0.0672 0.0735
Brugia malayi Endochitinase 0.0023 0.0026 0.0016
Schistosoma mansoni hypothetical protein 0.0082 0.0672 0.0735
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0377 0.3891 0.594
Onchocerca volvulus 0.0247 0.2474 0.7014
Loa Loa (eye worm) acetyltransferase 0.015 0.1408 0.154
Entamoeba histolytica hypothetical protein 0.0024 0.0041 0.0045
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0082 0.0672 0.0735
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0082 0.0672 0.0661
Echinococcus granulosus tachykinin peptides receptor 99D 0.0082 0.0672 0.0661
Schistosoma mansoni hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Brugia malayi hypothetical protein 0.0026 0.006 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.0672 0.0661
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.006 0.0121
Loa Loa (eye worm) chitinase I 0.0156 0.1475 0.1613
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.0672 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Giardia lamblia Hypothetical protein 0.0024 0.0041 0.0045
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0081 0.0662 0.0711
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.0672 0.0661
Schistosoma mansoni cyclin B3 0.0181 0.1749 0.1912
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0092 0.0783 0.1182
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0042 0.0238 1
Loa Loa (eye worm) histone deacetylase 11 0.0106 0.0935 0.1022
Brugia malayi cyclin-dependent kinase 7 homolog 0.0213 0.21 0.2286
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0024 0.0041 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0216 0.0313
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0081 0.0662 0.0723
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Schistosoma mansoni biogenic amine receptor 0.0082 0.0672 0.0735
Giardia lamblia Kinase, CAMK CAMKL 0.0134 0.1237 0.1877
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0092 0.0783 0.0856
Schistosoma mansoni hypothetical protein 0.005 0.0319 0.0349
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0081 0.0662 0.0651
Echinococcus granulosus serine:threonine protein kinase NLK 0.0134 0.1237 0.1227
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0081 0.0662 0.0723
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0264 0.2658 0.265
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni adenoreceptor 0.0082 0.0672 0.0735
Schistosoma mansoni serine/threonine kinase 0.0134 0.1237 0.1353
Trypanosoma brucei cdc2-related kinase 3 0.0103 0.0897 0.1356
Mycobacterium tuberculosis Carboxylesterase LipT 0.0145 0.1359 0.2019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0662 0.0723
Brugia malayi larval opioid receptor 0.0082 0.0672 0.0723
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Echinococcus multilocularis sodium and chloride dependent glycine 0.0042 0.0238 0.0227
Giardia lamblia Kinase, CMGC DYRK 0.062 0.6543 1
Brugia malayi Carboxylesterase family protein 0.0145 0.1359 0.1475
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Schistosoma mansoni lipoxygenase 0.0085 0.0704 0.077
Onchocerca volvulus 0.0081 0.0662 0.1821
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0652 0.6886 0.6882
Brugia malayi Glycosyl hydrolases family 18 protein 0.0023 0.0026 0.0016
Onchocerca volvulus Nischarin homolog 0.0213 0.2097 0.5936
Echinococcus multilocularis cyclin y 0.0024 0.0041 0.0029
Echinococcus granulosus tm gpcr rhodopsin 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Trypanosoma brucei protein kinase, putative 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Entamoeba histolytica cyclin, putative 0.0066 0.0496 0.0742
Loa Loa (eye worm) hypothetical protein 0.051 0.5336 0.5834
Loa Loa (eye worm) carboxylesterase 0.0145 0.1359 0.1486
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0081 0.0662 0.0651
Schistosoma mansoni biogenic amine (5HT) receptor 0.0471 0.4912 0.537
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Echinococcus granulosus neuropeptide receptor 0.0082 0.0672 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus cyclin dependent kinase 1 0.0103 0.0897 0.0886
Echinococcus multilocularis histone deacetylase 8 0.0106 0.0935 0.0924
Schistosoma mansoni sodium/chloride dependent transporter 0.0057 0.0398 0.0435
Echinococcus granulosus casein kinase i 0.0092 0.0783 0.0773
Echinococcus multilocularis 0.0372 0.3831 0.3824
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0132 0.0132
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0238 0.0227
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0081 0.0662 0.0711
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0897 0.0981
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0081 0.0662 0.0723
Leishmania major histone deacetylase, putative 0.0223 0.2204 0.3357
Toxoplasma gondii hypothetical protein 0.0042 0.0238 0.0347
Brugia malayi G-protein coupled receptor 0.0082 0.0672 0.0723
Plasmodium vivax hypothetical protein, conserved 0.0247 0.2474 0.6187
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0082 0.0672 0.0735
Trypanosoma cruzi mitotic cyclin, putative 0.0024 0.0041 0.0045
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0081 0.0662 0.0711
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0078 0.0101
Echinococcus multilocularis acetylcholinesterase 0.0859 0.9147 0.9146
Schistosoma mansoni cyclin G2 0.0024 0.0041 0.0045
Brugia malayi Pre-SET motif family protein 0.0212 0.209 0.2275
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0596 0.0651
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0029 0.0096 0.0105
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0041 0.0045
Brugia malayi Carboxylesterase family protein 0.0859 0.9147 1
Onchocerca volvulus 0.0113 0.1008 0.2813
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Trypanosoma cruzi casein kinase, putative 0.0092 0.0783 0.1182
Treponema pallidum sodium- and chloride- dependent transporter 0.025 0.2499 0.5
Toxoplasma gondii casein kinase I 0.0092 0.0783 0.1182
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus multilocularis cyclin dependent kinase 9 0.018 0.1743 0.1733
Echinococcus multilocularis dual specificity 0.062 0.6543 0.6539
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Plasmodium vivax chitinase 0.0023 0.0026 0.0036
Echinococcus granulosus g-protein coupled receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0024 0.0041 0.0045
Echinococcus multilocularis glycine receptor subunit beta 0.0081 0.0662 0.0651
Echinococcus multilocularis geminin 0.0173 0.166 0.165
Echinococcus granulosus cyclin dependent kinase 7 0.0094 0.0798 0.0787
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0033 0.0132 0.0132
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Trichomonas vaginalis cyclin B, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0122 0.1104 0.1094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0108 0.0118
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0897 0.1356
Brugia malayi hypothetical protein 0.0244 0.2439 0.2658
Echinococcus granulosus orexin receptor type 2 0.0082 0.0672 0.0661
Echinococcus granulosus snurportin 1 0.0314 0.3198 0.319
Echinococcus multilocularis neuropeptide FF receptor 2 0.0082 0.0672 0.0661
Echinococcus granulosus cyclin k 0.0024 0.0041 0.0029
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0096 0.013
Echinococcus granulosus cyclin A3 4 0.0024 0.0041 0.0029
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0264 0.2658 0.2906
Schistosoma mansoni hypothetical protein 0.0247 0.2474 0.2705
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Brugia malayi Serotonin receptor 0.0557 0.5854 0.6396
Schistosoma mansoni histone deacetylase 4 5 0.0223 0.2204 0.241
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Entamoeba histolytica protein kinase domain containing protein 0.0134 0.1237 0.1877
Echinococcus granulosus nAChR subunit 0.0081 0.0662 0.0651
Brugia malayi Melatonin receptor type 1A 0.0082 0.0672 0.0723
Trichomonas vaginalis cyclin A, putative 0.0024 0.0041 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0081 0.0662 0.0723
Schistosoma mansoni neurotransmitter gated ion channel 0.0049 0.0305 0.0334
Echinococcus granulosus Glycoside hydrolase chitinase domain containing protein 1 0.0023 0.0026 0.0014
Echinococcus granulosus G protein coupled receptor 139 0.0082 0.0672 0.0661
Echinococcus multilocularis nAChR subunit 0.0081 0.0662 0.0651
Echinococcus granulosus glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.0672 0.0661
Trichomonas vaginalis cyclins, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis neuropeptide receptor 0.0082 0.0672 0.0661
Mycobacterium tuberculosis Possible chitinase 0.0133 0.1225 0.1778
Echinococcus granulosus casein kinase I alpha 0.0092 0.0783 0.0773
Echinococcus granulosus allatostatin A receptor 0.0082 0.0672 0.0661
Plasmodium vivax protein kinase Crk2 0.0103 0.0897 0.2225
Giardia lamblia Cyclin B-like protein 0.0024 0.0041 0.0045
Echinococcus granulosus cyclins 0.0066 0.0496 0.0485
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0036 0.0037
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Trypanosoma cruzi histone deacetylase, putative 0.0106 0.0935 0.1414
Brugia malayi Protein kinase domain containing protein 0.0386 0.3991 0.4356
Brugia malayi hypothetical protein 0.0169 0.1614 0.1754
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0438 0.0479
Trichomonas vaginalis cyclin B, putative 0.0066 0.0496 0.0742
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0233 0.0556
Entamoeba histolytica hypothetical protein 0.0024 0.0036 0.0037
Echinococcus granulosus histone deacetylase 8 0.0106 0.0935 0.0924
Entamoeba histolytica hypothetical protein 0.0049 0.0305 0.045
Echinococcus multilocularis orexin receptor type 2 0.0082 0.0672 0.0661
Brugia malayi neuropeptide F receptor 0.0082 0.0672 0.0723
Plasmodium falciparum amino acid transporter, putative 0.0042 0.0238 0.0569
Onchocerca volvulus 0.0082 0.0672 0.1852
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0783 0.0856
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0256 0.0374
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0438 0.0479
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0122 0.1104 0.1094
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Echinococcus multilocularis cyclin G2 0.0024 0.0041 0.0029
Echinococcus multilocularis dual specificity 0.062 0.6543 0.6539
Echinococcus multilocularis histone deacetylase 1 0.0247 0.2472 0.2464
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0181 0.0186
Brugia malayi hypothetical protein 0.0024 0.0041 0.0032
Brugia malayi hypothetical protein 0.0127 0.1156 0.1252
Trichomonas vaginalis CK1 family protein kinase 0.0092 0.0783 0.1182
Onchocerca volvulus 0.0082 0.0672 0.1852
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0033 0.0132 0.012
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.026
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0132 0.0144
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0049 0.0305 0.0321
Loa Loa (eye worm) hypothetical protein 0.0247 0.2474 0.2705
Onchocerca volvulus 0.0082 0.0672 0.1852
Loa Loa (eye worm) norepinephrine transporter 0.025 0.2499 0.2732
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Loa Loa (eye worm) hypothetical protein 0.0127 0.1156 0.1264
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.0672 0.0735
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.006 0.0073
Echinococcus granulosus g protein coupled receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Trichomonas vaginalis cyclin D, putative 0.0066 0.0496 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.0377 0.3891 0.4254
Echinococcus multilocularis protoporphyrinogen oxidase 0.0042 0.0233 0.0222
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0897 0.1356
Echinococcus multilocularis 0.0042 0.0233 0.0222
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Trypanosoma cruzi cdc2-related kinase 3 0.0103 0.0897 0.1356
Trypanosoma brucei histone deacetylase 4 0.0223 0.2204 0.3357
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Loa Loa (eye worm) histone deacetylase 1 0.0247 0.2472 0.2703
Echinococcus granulosus biogenic amine 5HT receptor 0.0471 0.4912 0.4906
Echinococcus multilocularis cyclin 0.0094 0.0803 0.0792
Loa Loa (eye worm) hypothetical protein 0.0025 0.0054 0.0059
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Leishmania major hypothetical protein, conserved 0.0026 0.006 0.0073
Toxoplasma gondii histone lysine-specific demethylase 0.0042 0.0233 0.0339
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.046 0.0449
Loa Loa (eye worm) neuropeptide F receptor 0.0082 0.0672 0.0735
Brugia malayi Histone deacetylase family protein 0.0223 0.2204 0.24
Entamoeba histolytica protein kinase, putative 0.0377 0.3891 0.594
Leishmania major histone deacetylase, putative 0.0247 0.2472 0.3768
Brugia malayi GSG2 0.0652 0.6886 0.7525
Schistosoma mansoni Cyclin fold protein 0.0024 0.0041 0.0045
Onchocerca volvulus Cyclin L homolog 0.0024 0.0041 0.0043
Loa Loa (eye worm) CYL-1 protein 0.0024 0.0041 0.0045
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0595 0.6268 1
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Toxoplasma gondii hypothetical protein 0.0024 0.0041 0.0045
Echinococcus granulosus para nitrobenzyl esterase 0.0145 0.1359 0.1349
Giardia lamblia Kinase, CK1 Casein kinase 0.0092 0.0783 0.1182
Onchocerca volvulus 0.0033 0.0132 0.0304
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0042 0.0233 0.0556
Leishmania major histone deacetylase, putative 0.0223 0.2204 0.3357
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0471 0.4912 0.4906
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.0672 0.0735
Onchocerca volvulus 0.0042 0.0238 0.0608
Brugia malayi endochitinase 0.0156 0.1475 0.1602
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Loa Loa (eye worm) GABA receptor subunit 0.0049 0.0305 0.0334
Loa Loa (eye worm) hypothetical protein 0.0117 0.1055 0.1154
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0082 0.0672 0.0735
Onchocerca volvulus 0.0024 0.0041 0.0043
Echinococcus multilocularis cyclin dependent kinase 5 0.0103 0.0897 0.0886
Toxoplasma gondii histone deacetylase HDAC5 0.0106 0.0935 0.1414
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0859 0.9147 1
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0247 0.2474 0.2465
Onchocerca volvulus 0.0033 0.0132 0.0304
Leishmania major mitotic cyclin, putative 0.0024 0.0041 0.0045
Echinococcus granulosus neuropeptide FF receptor 2 0.0082 0.0672 0.0661
Onchocerca volvulus 0.025 0.2499 0.7088
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.046 0.0406
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0081 0.0662 0.0723
Plasmodium vivax SET domain protein, putative 0.003 0.0108 0.0241
Echinococcus multilocularis casein kinase I alpha 0.0092 0.0783 0.0773
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus cyclins 0.0066 0.0496 0.0485
Echinococcus granulosus serotonin transporter 0.025 0.2499 0.2491
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Onchocerca volvulus 0.0082 0.0672 0.1852
Schistosoma mansoni histone deacetylase hda2 0.0229 0.2273 0.2486
Loa Loa (eye worm) cyclin domain-containing protein 0.0181 0.1749 0.1912
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus granulosus serotonin receptor 0.0082 0.0672 0.0661
Trypanosoma cruzi histone deacetylase, putative 0.0223 0.2204 0.3357
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0049 0.0305 0.0334
Onchocerca volvulus 0.0117 0.1055 0.295
Schistosoma mansoni hypothetical protein 0.0119 0.1078 0.1178
Brugia malayi ORL1-like opioid receptor 0.0082 0.0672 0.0723
Schistosoma mansoni sodium-dependent amino acid transporter 0.0042 0.0238 0.026
Trypanosoma cruzi casein kinase, putative 0.0092 0.0783 0.1182
Echinococcus multilocularis cyclin B 0.0117 0.1055 0.1045
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0134 0.1237 0.1227
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Plasmodium vivax casein kinase 1, putative 0.0092 0.0783 0.1939
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0386 0.3991 0.6093
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Echinococcus multilocularis casein kinase I delta 0.0092 0.0783 0.0773
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0496 0.0742
Echinococcus granulosus cyclins 0.0066 0.0496 0.0485
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0247 0.2474 0.2705
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0033 0.0132 0.0132
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Leishmania major histone deacetylase, putative 0.0247 0.2472 0.3768
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.046 0.0449
Entamoeba histolytica protein kinase, putative 0.0377 0.3891 0.594
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0256 0.0374
Brugia malayi putative neuropeptide receptor NPR1 0.0082 0.0672 0.0723
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.006 0.0073
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0082 0.0672 0.0661
Brugia malayi cyclin-dependent kinase 9 0.0061 0.0441 0.047
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0024 0.0041 0.0074
Schistosoma mansoni opsin-like receptor 0.0082 0.0672 0.0735
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0347
Loa Loa (eye worm) hypothetical protein 0.0388 0.4004 0.4377
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0042 0.0238 0.0227
Loa Loa (eye worm) G-protein coupled receptor 0.0082 0.0672 0.0735
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0377 0.3891 0.4254
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.062 0.6543 1
Mycobacterium ulcerans chitinase/cellulase 0.0133 0.1225 0.1921
Brugia malayi Glycosyl hydrolases family 18 protein 0.0023 0.0026 0.0016
Echinococcus multilocularis cyclin dependent kinase 1 0.0103 0.0897 0.0886
Brugia malayi Cation transporter family protein 0.0081 0.0662 0.0711
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0256 0.0374
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0082 0.0672 0.0661
Echinococcus multilocularis dual specificity protein kinase clk2 0.0386 0.3991 0.3984
Onchocerca volvulus Cyclin L homolog 0.0024 0.0041 0.0043
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0082 0.0672 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus fmrfamide receptor 0.0082 0.0672 0.0661
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0036 0.0037
Plasmodium falciparum protoporphyrinogen oxidase 0.0042 0.0233 0.0556
Entamoeba histolytica casein kinase 1, putative 0.0092 0.0783 0.1182
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0082 0.0672 0.0735
Loa Loa (eye worm) cyclin domain-containing protein 0.0024 0.0041 0.0045
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0117 0.1055 0.1598
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0082 0.0672 0.0735
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0134 0.1237 0.1877
Echinococcus granulosus somatostatin receptor 0.0082 0.0672 0.0661
Trypanosoma brucei cyclin 3 0.0024 0.0041 0.0045
Schistosoma mansoni neuropeptide receptor 0.0082 0.0672 0.0735
Trichomonas vaginalis cyclins, putative 0.0076 0.06 0.0901
Schistosoma mansoni metabotropic glutamate receptor 0.0025 0.0054 0.0059
Entamoeba histolytica cyclin, domain containing protein 0.0024 0.0041 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0438 0.0479
Schistosoma mansoni hypothetical protein 0.0075 0.0596 0.0651
Loa Loa (eye worm) hypothetical protein 0.025 0.2499 0.2732
Leishmania major cyclin 9, putative 0.0024 0.0041 0.0045
Loa Loa (eye worm) hypothetical protein 0.0208 0.2044 0.2235
Echinococcus granulosus neuropeptide Y receptor 0.0082 0.0672 0.0661
Echinococcus multilocularis histone deacetylase 3 0.0247 0.2472 0.2464
Brugia malayi jmjC domain containing protein 0.0061 0.0438 0.0467
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0081 0.0662 0.0651
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1237 0.1877
Brugia malayi Dopamine receptor 0.0082 0.0672 0.0723
Plasmodium falciparum histone deacetylase, putative 0.0223 0.2204 0.5509
Onchocerca volvulus 0.0082 0.0672 0.1852
Loa Loa (eye worm) hypothetical protein 0.0169 0.1614 0.1765
Echinococcus multilocularis somatostatin receptor 0.0082 0.0672 0.0661
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0042 0.0233 0.0556
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0081 0.0662 0.0651
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0145 0.1359 0.2019
Plasmodium falciparum histone deacetylase 2 0.0223 0.2204 0.5509
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0082 0.0672 0.0723
Loa Loa (eye worm) histone deacetylase 7A 0.0223 0.2204 0.241
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Loa Loa (eye worm) cyclin domain-containing protein 0.0024 0.0041 0.0045
Trypanosoma cruzi histone deacetylase, putative 0.0223 0.2204 0.3357
Brugia malayi histone deacetylase 11 0.0106 0.0935 0.1011
Giardia lamblia Hypothetical protein 0.0024 0.0041 0.0045
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.006 0.0073
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.0672 0.0735
Brugia malayi SWIRM domain containing protein 0.0042 0.0233 0.0242
Giardia lamblia Kinase, CMGC CDK 0.0103 0.0897 0.1356
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi excitatory GABA receptor EXP-1A 0.0081 0.0662 0.0711
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Echinococcus granulosus cyclin y 0.0024 0.0041 0.0029
Onchocerca volvulus 0.0082 0.0672 0.1852
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Onchocerca volvulus 0.0042 0.0233 0.0593
Trichomonas vaginalis CK1 family protein kinase 0.0092 0.0783 0.1182
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0042 0.0238 0.026
Echinococcus multilocularis cyclin dependent kinase 0.0103 0.0897 0.0886
Trypanosoma cruzi cyclin 9, putative 0.0024 0.0041 0.0045
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0042 0.0238 0.0347
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Plasmodium vivax histone deacetylase 2, putative 0.0223 0.2204 0.5509
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0042 0.0238 0.0227
Loa Loa (eye worm) carboxylesterase 0.0859 0.9147 1
Trypanosoma brucei mitotic cyclin 6 0.0117 0.1055 0.1598
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.062 0.6543 0.7149
Schistosoma mansoni ran 0.0022 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0036 0.0037
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0042 0.0233 0.0556
Brugia malayi metabotropic glutamate receptor type 2 0.0025 0.0054 0.0046
Trichomonas vaginalis cyclin B, putative 0.0024 0.0041 0.0045
Loa Loa (eye worm) hypothetical protein 0.0859 0.9147 1
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Schistosoma mansoni serine/threonine protein kinase 0.0094 0.0798 0.0872
Entamoeba histolytica protein kinase domain containing protein 0.062 0.6543 1
Trichomonas vaginalis cyclin B3, putative 0.0066 0.0496 0.0742
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0553 0.5811 1
Toxoplasma gondii histone deacetylase HDAC2 0.0247 0.2472 0.3768
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.0672 0.0661
Trichomonas vaginalis cyclins, putative 0.0117 0.1055 0.1598
Echinococcus granulosus neuropeptide receptor A26 0.0082 0.0672 0.0661
Schistosoma mansoni biogenic amine receptor 0.0082 0.0672 0.0735
Brugia malayi histone deacetylase 3 (HD3) 0.0247 0.2472 0.2694
Schistosoma mansoni biogenic amine receptor 0.0082 0.0672 0.0735
Schistosoma mansoni nAChR subunit 0.0033 0.0132 0.0144
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.046 0.0503
Echinococcus granulosus g protein coupled receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Trypanosoma brucei protein kinase, putative 0.0113 0.1008 0.1525
Schistosoma mansoni survival motor neuron protein 0.005 0.0319 0.0349
Echinococcus granulosus g protein coupled receptor 0.0082 0.0672 0.0661
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0081 0.0662 0.0651
Echinococcus multilocularis acetylcholinesterase 0.0859 0.9147 0.9146
Entamoeba histolytica cell division protein kinase 2, putative 0.0222 0.2199 0.3349
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0343 0.3516 0.3844
Trichomonas vaginalis CMGC family protein kinase 0.0103 0.0897 0.1356
Echinococcus multilocularis nAChR subunit 0.0049 0.0305 0.0294
Schistosoma mansoni serine/threonine protein kinase 0.0061 0.0441 0.0482
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni neuropeptide receptor 0.0082 0.0672 0.0735
Trypanosoma brucei histone deacetylase 1 0.0247 0.2472 0.3768
Echinococcus granulosus dual specificity 0.062 0.6543 0.6539
Echinococcus multilocularis cyclin dependent kinase 9 0.0061 0.0441 0.043
Loa Loa (eye worm) hypothetical protein 0.051 0.5336 0.5834
Schistosoma mansoni neuropeptide receptor 0.0082 0.0672 0.0735
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Loa Loa (eye worm) cyclin domain-containing protein 0.0024 0.0041 0.0045
Onchocerca volvulus 0.0042 0.0238 0.0608
Loa Loa (eye worm) histone deacetylase 3 0.0247 0.2472 0.2703
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Schistosoma mansoni nAChR subunit 0.0081 0.0662 0.0723
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0092 0.0783 0.0856
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi Protein kinase domain containing protein 0.0134 0.1237 0.1342
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0082 0.0672 0.0735
Echinococcus granulosus cyclin y 0.0024 0.0041 0.0029
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0082 0.0672 0.0661
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0103 0.0897 0.1356
Entamoeba histolytica protein kinase domain containing protein 0.0377 0.3891 0.594
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Onchocerca volvulus 0.0241 0.2409 0.683
Brugia malayi histone deacetylase 1 (HD1) 0.0247 0.2472 0.2694
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Onchocerca volvulus 0.0082 0.0672 0.1852
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0049 0.0305 0.0334
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0063 0.0465 0.0417
Plasmodium falciparum glycogen synthase kinase 3 0.0113 0.1008 0.2503
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.062 0.6543 1
Loa Loa (eye worm) hypothetical protein 0.051 0.5336 0.5834
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Echinococcus multilocularis cyclin dependent kinase 7 0.0094 0.0798 0.0787
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.025 0.2499 0.2732
Giardia lamblia Histone deacetylase 0.0247 0.2472 0.3768
Echinococcus multilocularis histone deacetylase 7 0.0223 0.2204 0.2195
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0103 0.0897 0.0886
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Plasmodium vivax cyclin homologue, putative 0.0024 0.0041 0.0074
Loa Loa (eye worm) acetylcholinesterase 1 0.0859 0.9147 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0081 0.0662 0.0651
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus dual specificity 0.062 0.6543 0.6539
Trichomonas vaginalis cyclin H, putative 0.0065 0.0489 0.0732
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0319 0.0336
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0377 0.3891 0.594
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0081 0.0662 0.0723
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0042 0.0238 0.0227
Giardia lamblia G2/mitotic-specific cyclin B 0.0117 0.1055 0.1598
Brugia malayi putative neuropeptide receptor 0.0082 0.0672 0.0723
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132
Brugia malayi Cation transporter family protein 0.0081 0.0662 0.0711
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0081 0.0662 0.0723
Brugia malayi amine oxidase, flavin-containing family protein 0.0042 0.0233 0.0242
Trypanosoma brucei histone deacetylase 3 0.0223 0.2204 0.3357
Echinococcus granulosus acetylcholinesterase 0.0859 0.9147 0.9146
Schistosoma mansoni amine GPCR 0.0082 0.0672 0.0735
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Echinococcus granulosus cyclin B3 1 0.0066 0.0496 0.0485
Trichomonas vaginalis cyclins, putative 0.0024 0.0041 0.0045
Leishmania major cyclin 0.0117 0.1055 0.1598
Schistosoma mansoni amine oxidase 0.0042 0.0233 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.0134 0.1237 0.1353
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0063 0.0465 0.0704
Schistosoma mansoni alpha-1 adrenergic receptor 0.0082 0.0672 0.0735
Echinococcus multilocularis serotonin receptor 0.0208 0.2044 0.2035
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0305 0.0321
Echinococcus granulosus cyclin 0.0094 0.0803 0.0792
Trichomonas vaginalis cyclin D, putative 0.0066 0.0496 0.0742
Giardia lamblia Kinase, CAMK CAMKL 0.0134 0.1237 0.1877
Echinococcus granulosus histone deacetylase 0.0223 0.2204 0.2195
Brugia malayi hypothetical protein 0.0023 0.0026 0.0016
Plasmodium falciparum histone deacetylase 1 0.0247 0.2472 0.6184
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0094 0.0803 0.0792
Brugia malayi PAS domain containing protein 0.005 0.0324 0.0342
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0024 0.0041 0.0045
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0061 0.0441 0.0482
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0028 0.0078 0.0101
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0216 0.0513
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0349 0.3587 0.3922
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0134 0.1237 0.308
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0134 0.1237 0.1353
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Loa Loa (eye worm) hypothetical protein 0.0026 0.006 0.0065
Loa Loa (eye worm) melatonin receptor type 1A 0.0082 0.0672 0.0735
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0108 0.0147
Echinococcus granulosus alpha 1A adrenergic receptor 0.0082 0.0672 0.0661
Echinococcus granulosus histone deacetylase 6 0.0223 0.2204 0.2195
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Schistosoma mansoni hypothetical protein 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0082 0.0672 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0388 0.4004 0.437
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0081 0.0662 0.0651
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0438 0.0427
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0082 0.0672 0.0735
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0081 0.0662 0.0651
Brugia malayi Histone deacetylase 1 0.0247 0.2472 0.2694
Brugia malayi intracellular kinase 0.0113 0.1008 0.109
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0042 0.0233 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus glycine receptor subunit beta 0.0081 0.0662 0.0651
Brugia malayi Cyclin, N-terminal domain containing protein 0.0024 0.0041 0.0032
Trichomonas vaginalis cyclin A, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0063 0.0465 0.0497
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0108 0.0118
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Brugia malayi jmjC domain containing protein 0.0061 0.0438 0.0467
Echinococcus multilocularis g protein coupled receptor 0.0082 0.0672 0.0661
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0082 0.0672 0.0661
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0063 0.0465 0.0695
Echinococcus granulosus mitogen activated protein kinase 15 0.0134 0.1237 0.1227
Echinococcus granulosus dual specificity protein kinase clk2 0.0386 0.3991 0.3984
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi RNA, U transporter 1 0.0084 0.0687 0.074
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2472 0.3768
Brugia malayi RE15519p 0.0082 0.0672 0.0723
Loa Loa (eye worm) serotonin transporter b 0.025 0.2499 0.2732
Schistosoma mansoni cyclin k 0.0024 0.0041 0.0045
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0081 0.0662 0.0651
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.006 0.0073
Entamoeba histolytica histone deacetylase, putative 0.0247 0.2472 0.3768
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Brugia malayi Dopamine receptor protein 1 0.051 0.5336 0.5829
Onchocerca volvulus Protein CNPPD1 homolog 0.0024 0.0041 0.0043
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0042 0.0233 0.0339
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Echinococcus multilocularis casein kinase i 0.0092 0.0783 0.0773
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0033 0.0132 0.012
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.1363 0.1352
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0181 0.1749 0.174
Trypanosoma cruzi casein kinase, putative 0.0092 0.0783 0.1182
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0081 0.0662 0.0651
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0041 0.0045
Echinococcus granulosus cyclins 0.0066 0.0496 0.0485
Echinococcus granulosus sex peptide receptor 0.0082 0.0672 0.0661
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0081 0.0662 0.0651
Onchocerca volvulus 0.0082 0.0672 0.1852
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0377 0.3891 0.594
Onchocerca volvulus 0.0092 0.0783 0.217
Schistosoma mansoni cyclin B 0.0117 0.1055 0.1154
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.209 0.2285
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0081 0.0662 0.0651
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0386 0.3991 0.6093
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0081 0.0662 0.0711
Loa Loa (eye worm) cuticular endochitinase 0.0156 0.1475 0.1613
Trichomonas vaginalis cyclin B, putative 0.0117 0.1055 0.1598
Brugia malayi Carboxylesterase family protein 0.0859 0.9147 1
Schistosoma mansoni cyclin d 0.0024 0.0041 0.0045
Echinococcus multilocularis dual specificity 0.062 0.6543 0.6539
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0024 0.0041 0.0029
Echinococcus multilocularis g-protein coupled receptor 0.0082 0.0672 0.0661
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0134 0.1237 0.1877
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0024 0.0041 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0082 0.0672 0.0735
Onchocerca volvulus 0.0082 0.0672 0.1852
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0081 0.0662 0.0711
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0652 0.6886 0.6882
Toxoplasma gondii hypothetical protein 0.0042 0.0231 0.0335
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0113 0.1008 0.1525
Schistosoma mansoni serine/threonine protein kinase 0.0386 0.3991 0.4363
Loa Loa (eye worm) hypothetical protein 0.0023 0.0026 0.0028
Echinococcus granulosus cyclin dependent kinase 9 0.018 0.1743 0.1733
Trichomonas vaginalis CMGC family protein kinase 0.0113 0.1008 0.1525
Echinococcus multilocularis serotonin transporter 0.025 0.2499 0.2491
Brugia malayi Histone deacetylase family protein 0.0223 0.2204 0.24
Echinococcus multilocularis G protein coupled receptor 139 0.0082 0.0672 0.0661
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0081 0.0662 0.0651
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0041 0.0074
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0595 0.6268 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni BC026374 protein (S09 family) 0.0145 0.1359 0.1486
Trypanosoma cruzi casein kinase, putative 0.0092 0.0783 0.1182
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0081 0.0662 0.0723
Brugia malayi G protein-coupled receptor 0.0082 0.0672 0.0723
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Echinococcus multilocularis cyclins 0.0066 0.0496 0.0485
Trichomonas vaginalis cyclin B3, putative 0.0024 0.0041 0.0045
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0181 0.0249
Schistosoma mansoni hypothetical protein 0.0024 0.0041 0.0045
Echinococcus multilocularis allatostatin A receptor 0.0082 0.0672 0.0661
Onchocerca volvulus 0.0145 0.1359 0.382
Echinococcus granulosus Cyclin L1 0.0024 0.0041 0.0029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Leishmania major protein kinase, putative 0.0386 0.3991 0.6093
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0113 0.1008 0.0997
Loa Loa (eye worm) hypothetical protein 0.0033 0.0132 0.0144
Echinococcus multilocularis dual specificity 0.0377 0.3891 0.3884
Schistosoma mansoni jumonji domain containing protein 0.0061 0.0438 0.0479
Onchocerca volvulus 0.0247 0.2474 0.7014
Schistosoma mansoni hypothetical protein 0.0314 0.3198 0.3496
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis cyclins, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis neuropeptides capa receptor 0.0082 0.0672 0.0661
Brugia malayi casein kinase I 0.0092 0.0783 0.0845
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0063 0.0465 0.0454
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus multilocularis neuropeptide receptor A26 0.0082 0.0672 0.0661
Schistosoma mansoni amine GPCR 0.0253 0.2538 0.2775
Schistosoma mansoni amine oxidase 0.0042 0.0233 0.0255
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.006 0.0121
Onchocerca volvulus 0.005 0.0319 0.084
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0145 0.1359 0.2019
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0113 0.1008 0.0997
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0216 0.0313
Trypanosoma cruzi cyclin, putative 0.0117 0.1055 0.1598
Trichomonas vaginalis set domain proteins, putative 0.0241 0.2409 0.3671
Plasmodium falciparum cyclin 0.0066 0.0496 0.1217
Trypanosoma brucei casein kinase I, isoform 2 0.0092 0.0783 0.1182
Loa Loa (eye worm) ACC-1 protein 0.0081 0.0662 0.0723
Plasmodium vivax histone deacetylase, putative 0.0106 0.0935 0.232
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Onchocerca volvulus Neuropeptide F receptor homolog 0.0082 0.0672 0.1852
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Echinococcus multilocularis neuropeptide receptor 0.0082 0.0672 0.0661
Loa Loa (eye worm) cyclin domain-containing protein 0.0024 0.0041 0.0045
Echinococcus granulosus cyclin dependent kinase 9 0.0061 0.0441 0.043
Plasmodium vivax amine transporter, putative 0.0042 0.0238 0.0569
Brugia malayi G protein-coupled receptor F59B2.13 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Loa Loa (eye worm) hypothetical protein 0.0213 0.2097 0.2293
Echinococcus granulosus glycine receptor subunit beta 0.0081 0.0662 0.0651
Schistosoma mansoni serine/threonine protein kinase 0.062 0.6543 0.7153
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0042 0.0238 0.0248
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0238 0.0569
Trichomonas vaginalis cyclin B, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0827 0.8791 0.879
Entamoeba histolytica casein kinase, putative 0.0092 0.0783 0.1182
Plasmodium vivax histone deacetylase 1, putative 0.0247 0.2472 0.6184
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.026
Echinococcus granulosus casein kinase I alpha 0.0092 0.0783 0.0773
Giardia lamblia Kinase, CMGC CLK 0.0386 0.3991 0.6093
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0078 0.0624 0.0937
Echinococcus granulosus rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0051 0.0335 0.0366
Echinococcus granulosus lysine specific histone demethylase 1A 0.0042 0.0233 0.0222
Echinococcus granulosus acetylcholinesterase 0.0859 0.9147 0.9146
Schistosoma mansoni serine/threonine protein kinase 0.0343 0.3516 0.3844
Echinococcus granulosus sodium and chloride dependent glycine 0.0042 0.0238 0.0227
Echinococcus granulosus metabotropic glutamate receptor 5 0.0025 0.0054 0.0042
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0103 0.0897 0.0981
Trichomonas vaginalis CMGC family protein kinase 0.062 0.6543 1
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0145 0.1359 0.1349
Trypanosoma cruzi cyclin 6, putative 0.0117 0.1055 0.1598
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.0897 0.0981
Echinococcus granulosus hypothetical protein 0.0372 0.3831 0.3824
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0081 0.0662 0.0711
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0094 0.0803 0.0792
Schistosoma mansoni sodium/chloride dependent transporter 0.0042 0.0238 0.026
Brugia malayi endochitinase 0.0175 0.168 0.1826
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0181 0.017
Onchocerca volvulus 0.0145 0.1359 0.382
Schistosoma mansoni neuropeptide f receptor 76f 0.0082 0.0672 0.0735
Echinococcus granulosus serine:threonine protein kinase haspin 0.0652 0.6886 0.6882
Onchocerca volvulus 0.0145 0.1359 0.382
Schistosoma mansoni importin beta-1 0.0029 0.0096 0.0105
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0247 0.2474 0.2695
Echinococcus multilocularis Glycoside hydrolase, chitinase domain containing protein 1 0.0023 0.0026 0.0014
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0596 0.0585
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Loa Loa (eye worm) hypothetical protein 0.0388 0.4004 0.4377
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0082 0.0672 0.0735
Brugia malayi follicle stimulating hormone receptor 0.0082 0.0672 0.0723
Brugia malayi hypothetical protein 0.0082 0.0672 0.0723
Entamoeba histolytica cyclin family protein 0.0066 0.0496 0.0742
Echinococcus multilocularis casein kinase I alpha 0.0092 0.0783 0.0773
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.1408 0.154
Schistosoma mansoni amine GPCR 0.0082 0.0672 0.0735
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0036 0.0037
Echinococcus granulosus neuropeptide receptor 0.0082 0.0672 0.0661
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0132 0.0132
Loa Loa (eye worm) cyclin domain-containing protein 0.0024 0.0041 0.0045
Mycobacterium ulcerans carboxylesterase, LipT 0.0145 0.1359 0.2136
Loa Loa (eye worm) hypothetical protein 0.0145 0.1359 0.1486
Onchocerca volvulus 0.0082 0.0672 0.1852
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0662 0.0711
Onchocerca volvulus Putative endochitinase 0.0175 0.168 0.474
Giardia lamblia Cyclin A 0.0066 0.0496 0.0742
Schistosoma mansoni sodium/chloride dependent transporter 0.025 0.2499 0.2732
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0082 0.0672 0.0661
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0343 0.3516 0.3508
Schistosoma mansoni g1/s-specific cyclin C 0.0094 0.0803 0.0878
Echinococcus multilocularis casein kinase I delta 0.0092 0.0783 0.0773
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0082 0.0672 0.0735
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Echinococcus multilocularis rhodopsin orphan GPCR 0.0082 0.0672 0.0661
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0132 0.0144
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi sulfakinin receptor protein 0.0082 0.0672 0.0723
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0108 0.0096
Trichomonas vaginalis CMGC family protein kinase 0.0386 0.3991 0.6093
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0082 0.0672 0.0661
Echinococcus granulosus serine:threonine protein kinase haspin 0.0652 0.6886 0.6882
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0247 0.2472 0.3768
Brugia malayi Protein kinase domain containing protein 0.0343 0.3516 0.3836
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0386 0.3991 0.6093
Schistosoma mansoni histone deacetylase 0.0247 0.2472 0.2703
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0042 0.0233 0.0556
Echinococcus granulosus dro:myosuppressin receptor 0.0082 0.0672 0.0661
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.046 0.0686
Echinococcus granulosus neuropeptide s receptor 0.0082 0.0672 0.0661
Echinococcus multilocularis histone deacetylase 6 0.0223 0.2204 0.2195
Loa Loa (eye worm) hypothetical protein 0.0049 0.0305 0.0334
Trypanosoma brucei cyclin 9 0.0024 0.0041 0.0045
Brugia malayi Cation transporter family protein 0.0081 0.0662 0.0711
Schistosoma mansoni neuropeptide F-like receptor 0.0082 0.0672 0.0735
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0108 0.0096
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Brugia malayi Protein kinase domain containing protein 0.0377 0.3891 0.4247
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0113 0.1008 0.1525
Echinococcus multilocularis sex peptide receptor 0.0082 0.0672 0.0661
Brugia malayi Carboxylesterase family protein 0.0145 0.1359 0.1475
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0082 0.0672 0.1852
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0145 0.1359 0.1486
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0082 0.0672 0.0723
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0025 0.0054 0.0042
Giardia lamblia Kinase, CMGC GSK 0.0113 0.1008 0.1525
Echinococcus multilocularis cyclin t1 0.0024 0.0041 0.0029
Trichomonas vaginalis spcc417.12 protein, putative 0.0145 0.1359 0.2063
Leishmania major importin beta-1 subunit, putative 0.0024 0.0036 0.0037
Echinococcus multilocularis cyclin G2 0.0024 0.0041 0.0029
Trichomonas vaginalis cyclin B, putative 0.0117 0.1055 0.1598
Echinococcus multilocularis Cyclin L1 0.0024 0.0041 0.0029
Schistosoma mansoni histone deacetylase hda2 0.0106 0.0935 0.1022
Loa Loa (eye worm) hypothetical protein 0.0081 0.0662 0.0723
Giardia lamblia Cyclin fold protein 1, putative 0.0024 0.0041 0.0045
Onchocerca volvulus Putative endochitinase 0.0156 0.1475 0.4153
Brugia malayi casein kinase 1, delta 0.0092 0.0783 0.0845
Trypanosoma cruzi histone deacetylase 1, putative 0.0247 0.2472 0.3768
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0081 0.0662 0.0711
Trichomonas vaginalis histone deacetylase, putative 0.0247 0.2472 0.3768
Schistosoma mansoni growth hormone secretagogue receptor 0.0082 0.0672 0.0735
Schistosoma mansoni protein kinase 0.0134 0.1237 0.1353
Plasmodium falciparum casein kinase 1 0.0092 0.0783 0.1939
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0256 0.0244
Trypanosoma cruzi cdc2-related kinase 1 0.0103 0.0897 0.1356
Schistosoma mansoni lipoxygenase 0.0122 0.1104 0.1207
Brugia malayi Dopamine receptor protein 2 0.0082 0.0672 0.0723
Schistosoma mansoni ran 0.0022 0.0012 0.0013
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0081 0.0662 0.0723
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0264 0.2658 0.265
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0181 0.1749 0.174
Echinococcus multilocularis neuropeptide Y receptor 0.0082 0.0672 0.0661
Schistosoma mansoni hypothetical protein 0.0024 0.0041 0.0045
Echinococcus granulosus casein kinase I alpha 0.0092 0.0783 0.0773
Schistosoma mansoni kinase 0.0061 0.0441 0.0482
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Loa Loa (eye worm) hypothetical protein 0.0042 0.0233 0.0255
Echinococcus multilocularis para nitrobenzyl esterase 0.0145 0.1359 0.1349
Echinococcus granulosus cyclins 0.0066 0.0496 0.0485
Loa Loa (eye worm) hypothetical protein 0.0082 0.0672 0.0735
Onchocerca volvulus Putative endochitinase 0.0156 0.1475 0.4153
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0378 0.0414
Plasmodium vivax importin-beta 2, putative 0.0029 0.0096 0.0213
Trichomonas vaginalis CAMK family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis protein kinase atmrk1, putative 0.0134 0.1237 0.1877
Echinococcus granulosus cyclin b3 0.0066 0.0496 0.0485
Trichomonas vaginalis AGC family protein kinase 0.0134 0.1237 0.1877
Trichomonas vaginalis CMGC family protein kinase 0.0134 0.1237 0.1877
Echinococcus granulosus neuroligin 0.0145 0.1359 0.1349
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0042 0.0233 0.0255
Brugia malayi Cyclin, N-terminal domain containing protein 0.0117 0.1055 0.1143
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0028 0.0078 0.0101
Schistosoma mansoni histone deacetylase 0.0247 0.2472 0.2703
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0134 0.1237 0.308
Loa Loa (eye worm) hypothetical protein 0.0123 0.1114 0.1218
Echinococcus granulosus survival motor neuron protein 1 0.0244 0.2439 0.2431
Loa Loa (eye worm) cyclin domain-containing protein 0.016 0.1517 0.1658
Schistosoma mansoni cyclin l 0.0024 0.0041 0.0045
Brugia malayi hypothetical protein 0.0033 0.0132 0.0132

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 7.1 nM Inhibitory activity against human cyclin-dependent kinase 2 (CDK2) ChEMBL. 11728181
IC50 (binding) = 43 nM Inhibitory activity against human cyclin-dependent kinase 1 (CDK1) ChEMBL. 11728181

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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