Detailed information for compound 307925

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 287.403 | Formula: C16H25N5
  • H donors: 0 H acceptors: 3 LogP: 3.69 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1nc2ncnn2c2c1CCN2C(CC(C)(C)C)(C)C
  • InChi: 1S/C16H25N5/c1-11-12-7-8-20(16(5,6)9-15(2,3)4)13(12)21-14(19-11)17-10-18-21/h10H,7-9H2,1-6H3
  • InChiKey: QIPMDBFUGRCGHQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii cell-cycle-associated protein kinase DYRK2, putative 0.0555 0.3768 1
Echinococcus granulosus cyclin y 0.0025 0.0001 0.0001
Entamoeba histolytica cyclin C, putative 0.0025 0.0001 0.0002
Onchocerca volvulus 0.0143 0.0843 0.3618
Echinococcus granulosus neuropeptides capa receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0069 0.0318 0.0317
Echinococcus multilocularis histone deacetylase 6 0.0226 0.1429 0.1429
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1431 1 1
Trypanosoma cruzi CYC2-like cyclin, putative 0.0119 0.0671 0.0671
Brugia malayi hypothetical protein 0.0171 0.104 0.1039
Echinococcus granulosus G protein coupled receptor 139 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0503 0.3398 0.3397
Echinococcus granulosus orexin receptor type 2 0.0069 0.0318 0.0318
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0082 0.0411 0.041
Loa Loa (eye worm) acetylcholinesterase 1 0.0847 0.5845 0.5844
Entamoeba histolytica protein kinase, putative 0.0119 0.0671 0.1781
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0631
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni histamine h1 receptor 0.0069 0.0318 0.0542
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0069 0.0318 0.0318
Echinococcus granulosus cyclin dependent kinase 7 0.0099 0.0533 0.0533
Giardia lamblia Kinase, CAMK CAMKL 0.0123 0.0698 0.185
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Onchocerca volvulus 0.0069 0.0318 0.1361
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Brugia malayi hypothetical protein 0.0033 0.0061 0.006
Brugia malayi Carboxylesterase family protein 0.0143 0.0843 0.0842
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0143 0.0843 0.144
Entamoeba histolytica cell division protein kinase 2, putative 0.0212 0.1333 0.3537
Echinococcus multilocularis casein kinase I alpha 0.0098 0.0523 0.0523
Trypanosoma brucei protein kinase, putative 0.0119 0.0671 0.0671
Plasmodium vivax serine/threonine kinase-1, putative 0.0396 0.2642 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0318 0.0318
Echinococcus granulosus tachykinin peptides receptor 99D 0.0069 0.0318 0.0318
Brugia malayi AKH receptor 0.0069 0.0318 0.0317
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0143 0.0377
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0069 0.0318 0.0542
Echinococcus granulosus cyclins 0.0025 0.0001 0.0001
Trichomonas vaginalis cyclins, putative 0.0067 0.0301 0.0798
Brugia malayi histone deacetylase 3 (HD3) 0.0251 0.1607 0.1606
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.1607 0.4263
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0277 0.0734
Treponema pallidum sodium- and chloride- dependent transporter 0.0342 0.2257 0.5
Schistosoma mansoni hypothetical protein 0.005 0.0185 0.0314
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Echinococcus multilocularis Cyclin L1 0.0025 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0119 0.0671 0.067
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0033 0.0057 0.0057
Echinococcus granulosus hypothetical protein 0.0377 0.2504 0.2504
Loa Loa (eye worm) hypothetical protein 0.0503 0.3398 0.3397
Schistosoma mansoni opsin-like receptor 0.0069 0.0318 0.0542
Schistosoma mansoni amine GPCR 0.0243 0.155 0.265
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0069 0.0318 0.0318
Trichomonas vaginalis cyclin B, putative 0.0119 0.0671 0.1778
Brugia malayi cyclin-dependent kinase 7 homolog 0.0203 0.1267 0.1267
Leishmania major protein kinase, putative 0.0396 0.2642 0.2642
Entamoeba histolytica protein kinase, putative 0.0298 0.1945 0.5161
Trypanosoma cruzi casein kinase, putative 0.0098 0.0523 0.0523
Loa Loa (eye worm) G-protein coupled receptor 0.0069 0.0318 0.0317
Echinococcus granulosus dual specificity 0.0555 0.3768 0.3768
Trypanosoma cruzi cyclin 9, putative 0.0025 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.0152 0.0904 0.0903
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0069 0.0318 0.0542
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Entamoeba histolytica hypothetical protein 0.0298 0.1945 0.5161
Leishmania major histone deacetylase, putative 0.0226 0.1429 0.1429
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0277 0.0277
Echinococcus granulosus cyclin A3 4 0.0025 0.0001 0.0001
Plasmodium falciparum protoporphyrinogen oxidase 0.0063 0.0272 0.1027
Loa Loa (eye worm) hypothetical protein 0.0108 0.0591 0.059
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0069 0.0318 0.0318
Echinococcus granulosus cyclin B3 1 0.0067 0.0301 0.0301
Trypanosoma brucei Mitogen-activated protein kinase 10, putative 0.0123 0.0698 0.0698
Echinococcus multilocularis transfer RNA-Lys 0.0038 0.0094 0.0094
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0082 0.0411 0.041
Trypanosoma cruzi histone deacetylase, putative 0.0226 0.1429 0.1429
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0069 0.0318 0.0317
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0061 0.0103
Brugia malayi RE15519p 0.0069 0.0318 0.0317
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Schistosoma mansoni lipoxygenase 0.0123 0.0703 0.1202
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0352 0.2328 0.2328
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Onchocerca volvulus 0.0033 0.0061 0.0258
Brugia malayi hypothetical protein 0.0033 0.0061 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0045 0.0045
Onchocerca volvulus 0.0143 0.0843 0.3618
Onchocerca volvulus 0.0069 0.0318 0.1361
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus granulosus mitogen activated protein kinase 14 0.1431 1 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0116 0.0309
Onchocerca volvulus 0.0245 0.1565 0.6721
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0058 0.0238 0.0238
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0069 0.0318 0.0317
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Brugia malayi cyclin-dependent kinase 9 0.0066 0.0297 0.0296
Loa Loa (eye worm) histone deacetylase 11 0.0108 0.0591 0.059
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0063 0.0272 0.072
Brugia malayi hypothetical protein 0.0216 0.1359 0.1358
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Brugia malayi Cell division protein kinase 2 0.0123 0.0698 0.0697
Loa Loa (eye worm) hypothetical protein 0.0136 0.0795 0.0794
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni neuropeptide F-like receptor 0.0069 0.0318 0.0542
Brugia malayi hypothetical protein 0.0128 0.0737 0.0736
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Leishmania major histone deacetylase, putative 0.0251 0.1607 0.1607
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0396 0.2642 0.2642
Schistosoma mansoni hypothetical protein 0.0069 0.0318 0.0542
Echinococcus multilocularis casein kinase I delta 0.0098 0.0523 0.0523
Schistosoma mansoni amine GPCR 0.0069 0.0318 0.0542
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0277 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Entamoeba histolytica protein kinase, putative 0.0555 0.3768 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Echinococcus multilocularis casein kinase I alpha 0.0098 0.0523 0.0523
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0631
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0045 0.0075
Leishmania major histone deacetylase, putative 0.0251 0.1607 0.1607
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0318 0.0318
Echinococcus granulosus Cyclin L1 0.0025 0.0001 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0298 0.1945 0.3326
Brugia malayi excitatory GABA receptor EXP-1A 0.0082 0.0411 0.041
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0049 0.0175 0.0175
Plasmodium falciparum histone deacetylase 1 0.0251 0.1607 0.6081
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0268 0.173 0.173
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Brugia malayi hypothetical protein 0.0058 0.0238 0.0238
Entamoeba histolytica cyclin, putative 0.0119 0.0671 0.178
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0277 0.0473
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0082 0.0411 0.0411
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0033 0.0061 0.0061
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Leishmania major protein kinase, putative 0.0033 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Trypanosoma cruzi cyclin, putative 0.0119 0.0671 0.0671
Loa Loa (eye worm) hypothetical protein 0.0026 0.0009 0.0008
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0069 0.0318 0.0317
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0069 0.0318 0.0318
Echinococcus granulosus tm gpcr rhodopsin 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypoxia-induced factor 1 0.0158 0.0946 0.0945
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0143 0.0843 0.1048
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0095 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0411 0.0411
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.003 0.0037 0.0036
Echinococcus granulosus sex peptide receptor 0.0069 0.0318 0.0318
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.0671 0.1781
Giardia lamblia Kinase, CMGC CLK 0.0396 0.2642 0.701
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Leishmania major cyclin 0.0119 0.0671 0.0671
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0013 0.0046
Trichomonas vaginalis cyclins, putative 0.0119 0.0671 0.1778
Brugia malayi Importin beta-1 subunit 0.003 0.0037 0.0036
Brugia malayi larval opioid receptor 0.0069 0.0318 0.0317
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0143 0.0843 0.144
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0105 0.0104
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0069 0.0318 0.0318
Trypanosoma cruzi histone deacetylase 1, putative 0.0251 0.1607 0.1607
Echinococcus granulosus acetylcholinesterase 0.0847 0.5845 0.5845
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0318 0.0542
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0396 0.2642 0.2642
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0352 0.2328 1
Echinococcus granulosus snurportin 1 0.0318 0.2086 0.2086
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0069 0.0318 0.0542
Onchocerca volvulus Neuropeptide F receptor homolog 0.0069 0.0318 0.1361
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0082 0.0411 0.0411
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0098 0.0523 0.0522
Schistosoma mansoni histone deacetylase hda2 0.0108 0.0591 0.101
Onchocerca volvulus 0.0082 0.0411 0.1761
Plasmodium vivax amine transporter, putative 0.0058 0.0238 0.0899
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Plasmodium vivax histone deacetylase 2, putative 0.0226 0.1429 0.541
Echinococcus multilocularis cyclin b3 0.0067 0.0301 0.0301
Brugia malayi Dopamine receptor protein 1 0.0503 0.3398 0.3397
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0352 0.2328 0.2327
Loa Loa (eye worm) hypothetical protein 0.0254 0.163 0.1629
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0069 0.0318 0.1361
Brugia malayi Carboxylesterase family protein 0.0143 0.0843 0.0842
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0058 0.0238 0.0238
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0277 0.0277
Loa Loa (eye worm) hypothetical protein 0.0171 0.104 0.1039
Onchocerca volvulus 0.0069 0.0318 0.1361
Schistosoma mansoni opsin-like receptor 0.0069 0.0318 0.0542
Schistosoma mansoni serine/threonine protein kinase 0.0123 0.0698 0.1193
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) cytochrome P450 family protein 0.004 0.0112 0.0111
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0025 0.0001 0.0001
Onchocerca volvulus Putative endochitinase 0.0179 0.1099 0.4719
Plasmodium falciparum glycogen synthase kinase 3 0.0119 0.0671 0.2538
Onchocerca volvulus 0.0143 0.0843 0.3618
Echinococcus granulosus Hepatocellular carcinoma associated antigen 59 0.0254 0.163 0.163
Onchocerca volvulus 0.0033 0.0061 0.0258
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0598 0.1022
Mycobacterium ulcerans protoporphyrinogen oxidase 0.0063 0.0272 0.0294
Brugia malayi casein kinase I 0.0098 0.0523 0.0522
Mycobacterium ulcerans chitinase/cellulase 0.0136 0.0795 0.1155
Loa Loa (eye worm) solute carrier family 6 member 4 0.0342 0.2257 0.2257
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Brugia malayi Cation transporter family protein 0.0082 0.0411 0.041
Echinococcus granulosus cyclin dependent kinase 9 0.017 0.1032 0.1032
Loa Loa (eye worm) hypothetical protein 0.0118 0.0664 0.0663
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0069 0.0318 0.0318
Echinococcus granulosus hypothetical protein 0.0069 0.0318 0.0318
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0082 0.0411 0.0701
Brugia malayi Histone deacetylase 1 0.0251 0.1607 0.1606
Loa Loa (eye worm) hypothetical protein 0.0279 0.1807 0.1807
Trypanosoma cruzi casein kinase, putative 0.0098 0.0523 0.0523
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0143 0.0843 0.2234
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Onchocerca volvulus 0.0058 0.0238 0.1021
Brugia malayi Pre-SET motif family protein 0.0215 0.1354 0.1353
Echinococcus granulosus 7TM GPCR rhodopsin 0.0069 0.0318 0.0318
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0281 0.0017
Plasmodium vivax casein kinase 1, putative 0.0098 0.0523 0.1978
Echinococcus granulosus cyclin t1 0.0025 0.0001 0.0001
Trypanosoma brucei histone deacetylase, putative 0.0226 0.1429 0.1429
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0238 0.0899
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0263 0.0262
Loa Loa (eye worm) haspin protein kinase 0.0578 0.3935 0.3934
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0411 0.041
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0277 0.0473
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0069 0.0318 0.0542
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0411 0.0701
Brugia malayi putative neuropeptide receptor NPR1 0.0069 0.0318 0.0317
Echinococcus multilocularis orexin receptor type 2 0.0069 0.0318 0.0318
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0396 0.2642 0.2642
Trypanosoma brucei protein kinase, putative 0.0123 0.0698 0.0698
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0281 0.0281
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0069 0.0318 0.0317
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0892 0.6164 1
Brugia malayi intracellular kinase 0.0119 0.0671 0.067
Plasmodium falciparum casein kinase 1 0.0098 0.0523 0.1978
Plasmodium vivax hypothetical protein, conserved 0.0254 0.163 0.6167
Loa Loa (eye worm) hypothetical protein 0.0052 0.0195 0.0194
Echinococcus granulosus casein kinase i 0.0098 0.0523 0.0523
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0045 0.0045
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Loa Loa (eye worm) hypothetical protein 0.034 0.2243 0.2242
Entamoeba histolytica chitinase, putative 0.016 0.0962 0.2553
Brugia malayi SWIRM domain containing protein 0.0063 0.0272 0.0271
Schistosoma mansoni hypothetical protein 0.0069 0.0318 0.0542
Brugia malayi Cyclin, N-terminal domain containing protein 0.0119 0.0671 0.067
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0069 0.0318 0.0318
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Trypanosoma cruzi casein kinase, putative 0.0098 0.0523 0.0523
Trichomonas vaginalis cyclin H, putative 0.0066 0.0297 0.0786
Echinococcus granulosus tm gpcr rhodopsin 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Loa Loa (eye worm) CMGC/CDK/CRK7 protein kinase 0.0123 0.0698 0.0697
Echinococcus multilocularis nAChR subunit 0.0049 0.0175 0.0175
Giardia lamblia Kinase, CMGC GSK 0.0119 0.0671 0.1779
Onchocerca volvulus 0.0119 0.0671 0.2879
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0533 0.091
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Onchocerca volvulus 0.0069 0.0318 0.1361
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0098 0.0523 0.0522
Onchocerca volvulus 0.0069 0.0318 0.1361
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Loa Loa (eye worm) cyclin domain-containing protein 0.0162 0.0976 0.0975
Schistosoma mansoni biogenic amine receptor 0.0069 0.0318 0.0542
Loa Loa (eye worm) hypothetical protein 0.0089 0.0461 0.046
Brugia malayi Cation transporter family protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0197 0.1224 0.1223
Echinococcus granulosus neuropeptide Y receptor 0.0069 0.0318 0.0318
Leishmania major cytochrome p450-like protein 0.0039 0.0105 0.0105
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0411 0.0411
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0143 0.0843 0.0843
Echinococcus granulosus para nitrobenzyl esterase 0.0143 0.0843 0.0843
Echinococcus multilocularis Cell division cycle 2 protein kinase 0.0123 0.0698 0.0698
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) carboxylesterase 0.0143 0.0843 0.0842
Entamoeba histolytica cell division protein kinase 2, putative 0.0109 0.0598 0.1588
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0377 0.2504 0.2504
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Plasmodium falciparum importin beta, putative 0.003 0.0037 0.0138
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0352 0.2328 0.2328
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Schistosoma mansoni amine GPCR 0.0069 0.0318 0.0542
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1431 1 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Leishmania major protein kinase, putative,dual-specificity protein kinase, putative 0.0555 0.3768 0.3768
Echinococcus multilocularis cyclin dependent kinase 1 0.0109 0.0598 0.0598
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0268 0.173 0.173
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus multilocularis dual specificity 0.0555 0.3768 0.3768
Echinococcus granulosus g-protein coupled receptor 0.0069 0.0318 0.0318
Onchocerca volvulus 0.0069 0.0318 0.1361
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0143 0.0377
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Echinococcus granulosus biogenic amine 5HT receptor 0.0197 0.1224 0.1224
Echinococcus granulosus Pfam-B_8186 domain containing protein 0.0103 0.056 0.056
Echinococcus granulosus acetylcholinesterase 0.0847 0.5845 0.5845
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Loa Loa (eye worm) carboxylesterase 0.0143 0.0843 0.0842
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0082 0.0411 0.0411
Trichomonas vaginalis set domain proteins, putative 0.0245 0.1565 0.4151
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) histone deacetylase 3 0.0251 0.1607 0.1606
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0215 0.1354 0.1353
Echinococcus granulosus allatostatin A receptor 0.0069 0.0318 0.0318
Brugia malayi sulfakinin receptor protein 0.0069 0.0318 0.0317
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0119 0.0671 0.1147
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0063 0.0272 0.1027
Schistosoma mansoni g1/s-specific cyclin C 0.0095 0.0504 0.0861
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0119 0.0671 0.1779
Echinococcus granulosus lysine specific histone demethylase 1A 0.0063 0.0272 0.0272
Brugia malayi histone deacetylase 11 0.0108 0.0591 0.059
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0026 0.0009 0.0009
Onchocerca volvulus Putative endochitinase 0.0179 0.1099 0.4719
Trichomonas vaginalis cyclin D, putative 0.0067 0.0301 0.0798
Entamoeba histolytica protein kinase domain containing protein 0.0298 0.1945 0.5161
Entamoeba histolytica protein kinase domain containing protein 0.0123 0.0698 0.1852
Echinococcus multilocularis snurportin 1 0.0318 0.2086 0.2086
Trichomonas vaginalis protein kinase atmrk1, putative 0.0123 0.0698 0.185
Trichomonas vaginalis CK1 family protein kinase 0.0098 0.0523 0.1386
Onchocerca volvulus 0.0069 0.0318 0.1361
Schistosoma mansoni acetylcholine receptor-related 0.0033 0.0061 0.0103
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0069 0.0318 0.0318
Schistosoma mansoni nAChR subunit 0.0033 0.0061 0.0103
Entamoeba histolytica histone deacetylase, putative 0.0251 0.1607 0.4264
Echinococcus multilocularis importin subunit beta 1 0.003 0.0037 0.0037
Echinococcus multilocularis cyclin B 0.0119 0.0671 0.0671
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1431 1 1
Onchocerca volvulus 0.0079 0.0386 0.1654
Brugia malayi GnHR receptor homolog 0.0069 0.0318 0.0317
Loa Loa (eye worm) GABA receptor subunit 0.0049 0.0175 0.0175
Echinococcus multilocularis dual specificity 0.0555 0.3768 0.3768
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0631
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis acetylcholinesterase 0.0847 0.5845 0.5845
Loa Loa (eye worm) hypothetical protein 0.0379 0.2518 0.2517
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0066 0.0297 0.0296
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0075
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0318 0.0542
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0411 0.041
Schistosoma mansoni importin beta-1 0.003 0.0037 0.0062
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0396 0.2642 0.701
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0082 0.0411 0.0411
Trichomonas vaginalis G protein-coupled receptor kinase, putative 0.0123 0.0698 0.185
Toxoplasma gondii histone deacetylase HDAC4 0.0108 0.0591 0.1567
Echinococcus multilocularis 0.0063 0.0272 0.0272
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0143 0.0377
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0411 0.0701
Echinococcus granulosus histone deacetylase 1 0.0251 0.1607 0.1607
Echinococcus granulosus cyclins 0.0067 0.0301 0.0301
Onchocerca volvulus 0.0069 0.0318 0.1361
Echinococcus multilocularis dual specificity 0.0298 0.1945 0.1945
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni cyclin B 0.0119 0.0671 0.1146
Leishmania major casein kinase, putative 0.0098 0.0523 0.0523
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0238 0.0238
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0098 0.0523 0.0522
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0272 0.1027
Trypanosoma cruzi casein kinase, putative 0.0098 0.0523 0.0523
Schistosoma mansoni neuropeptide receptor 0.0069 0.0318 0.0542
Echinococcus granulosus biogenic amine 5HT receptor 0.0463 0.3118 0.3118
Loa Loa (eye worm) hypothetical protein 0.0128 0.0737 0.0736
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0411 0.0701
Echinococcus multilocularis dual specificity protein kinase clk2 0.0396 0.2642 0.2642
Mycobacterium ulcerans monoamine oxidase 0.0063 0.0272 0.0294
Entamoeba histolytica hypothetical protein 0.0066 0.0297 0.0788
Brugia malayi amine oxidase, flavin-containing family protein 0.0063 0.0272 0.0271
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0105 0.0105
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus granulosus casein kinase I alpha 0.0098 0.0523 0.0523
Echinococcus granulosus g protein coupled receptor 0.0069 0.0318 0.0318
Trypanosoma brucei mitotic cyclin 0.0025 0.0001 0.0001
Giardia lamblia Histone deacetylase 0.0251 0.1607 0.4263
Onchocerca volvulus 0.0049 0.0175 0.075
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0185 0.0184
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0396 0.2642 0.701
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0061 0.006
Echinococcus granulosus cyclins 0.0067 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0049 0.0175 0.0299
Echinococcus multilocularis cyclin dependent kinase 5 0.0109 0.0598 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni myosin xvIII 0.0069 0.0318 0.0542
Loa Loa (eye worm) haspin protein kinase 0.0559 0.3798 0.3797
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0298 0.1945 0.1945
Echinococcus granulosus somatostatin receptor 0.0069 0.0318 0.0318
Plasmodium vivax histone deacetylase 1, putative 0.0251 0.1607 0.6081
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0045 0.0117
Brugia malayi Serotonin receptor 0.0069 0.0318 0.0317
Echinococcus granulosus fmrfamide receptor 0.0069 0.0318 0.0318
Trypanosoma cruzi casein kinase, putative 0.0098 0.0523 0.0523
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Echinococcus multilocularis cyclin k 0.0025 0.0001 0.0001
Echinococcus granulosus cyclins 0.0067 0.0301 0.0301
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0281 0.0281
Brugia malayi jmjC domain containing protein 0.0062 0.0263 0.0262
Schistosoma mansoni lipoxygenase 0.0086 0.0439 0.075
Echinococcus granulosus neuropeptide s receptor 0.0069 0.0318 0.0318
Schistosoma mansoni amine oxidase 0.0063 0.0272 0.0464
Trypanosoma brucei cdc2-related kinase 3 0.0109 0.0598 0.0598
Schistosoma mansoni serine/threonine protein kinase 0.0555 0.3768 0.6447
Echinococcus granulosus neuroligin 0.0143 0.0843 0.0843
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0063 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0281 0.0309
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0698 0.185
Giardia lamblia Cyclin A 0.0067 0.0301 0.0798
Brugia malayi hypothetical protein 0.0143 0.0843 0.0842
Trypanosoma brucei cyclin 9 0.0025 0.0001 0.0001
Echinococcus granulosus casein kinase I delta 0.0098 0.0523 0.0523
Brugia malayi hypothetical protein 0.0033 0.0061 0.006
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0123 0.0698 0.0698
Echinococcus granulosus dual specificity 0.0555 0.3768 0.3768
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0082 0.0411 0.0701
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Brugia malayi hypothetical protein 0.0247 0.1585 0.1584
Echinococcus multilocularis protoporphyrinogen oxidase 0.0063 0.0272 0.0272
Schistosoma mansoni neurotransmitter gated ion channel 0.0033 0.0061 0.0103
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Echinococcus granulosus histone deacetylase 3 0.0251 0.1607 0.1607
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0076 0.0367 0.0367
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0037 0.0037
Entamoeba histolytica hypothetical protein 0.0103 0.056 0.1487
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.0598 0.1022
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Brugia malayi hypothetical protein 0.0033 0.0061 0.006
Echinococcus multilocularis histone deacetylase 3 0.0251 0.1607 0.1607
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0379 0.2518 0.4307
Schistosoma mansoni histone deacetylase hda2 0.0232 0.1475 0.2523
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus cyclin k 0.0025 0.0001 0.0001
Brugia malayi Carboxylesterase family protein 0.0847 0.5845 0.5844
Loa Loa (eye worm) hypothetical protein 0.0285 0.1851 0.1851
Plasmodium vivax SET domain protein, putative 0.0031 0.0045 0.0166
Brugia malayi ORL1-like opioid receptor 0.0069 0.0318 0.0317
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0069 0.0318 0.0542
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0342 0.2257 0.2257
Echinococcus multilocularis cyclin dependent kinase 1 0.0109 0.0598 0.0598
Echinococcus granulosus histone deacetylase 0.0226 0.1429 0.1429
Brugia malayi Serotonin receptor 0.1002 0.6951 0.695
Echinococcus multilocularis G-protein coupled receptor, putative 0.0069 0.0318 0.0318
Echinococcus multilocularis cyclin B3 1 0.0067 0.0301 0.0301
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0411 0.0411
Echinococcus granulosus cyclin B 0.0119 0.0671 0.0671
Schistosoma mansoni neuropeptide f receptor 76f 0.0069 0.0318 0.0542
Leishmania major UDP-galactopyranose mutase 0.0063 0.0272 0.0272
Schistosoma mansoni hypothetical protein 0.0076 0.0367 0.0626
Loa Loa (eye worm) LGC-31 protein 0.0082 0.0411 0.041
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0082 0.0411 0.041
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0082 0.0411 0.041
Schistosoma mansoni histone deacetylase 0.0251 0.1607 0.2748
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Entamoeba histolytica hypothetical protein 0.0076 0.0367 0.0974
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0281 0.028
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0277 0.0303
Brugia malayi hypothetical protein 0.0559 0.3798 0.3797
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0298 0.1945 0.1944
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0411 0.0411
Entamoeba histolytica hypothetical protein 0.0076 0.0367 0.0974
Brugia malayi Melatonin receptor type 1A 0.0069 0.0318 0.0317
Plasmodium falciparum conserved protein, unknown function 0.0254 0.163 0.6167
Brugia malayi Cyclin, N-terminal domain containing protein 0.0119 0.0671 0.067
Schistosoma mansoni biogenic amine receptor 0.0069 0.0318 0.0542
Brugia malayi Cytochrome P450 family protein 0.0039 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0268 0.173 0.2958
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni histone deacetylase 4 5 0.0226 0.1429 0.2445
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0598 0.1585
Trypanosoma brucei histone deacetylase 1 0.0251 0.1607 0.1607
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0318 0.2086 0.2085
Echinococcus granulosus metabotropic glutamate receptor 5 0.0026 0.0009 0.0009
Echinococcus multilocularis hypothetical protein 0.0103 0.056 0.056
Echinococcus multilocularis mitogen activated protein kinase 11 0.1431 1 1
Leishmania major mitotic cyclin, putative 0.0025 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0069 0.0318 0.0318
Echinococcus granulosus protein kinase shaggy 0.0119 0.0671 0.0671
Giardia lamblia Kinase, CMGC DYRK 0.0555 0.3768 1
Echinococcus multilocularis carboxylesterase 5A 0.0847 0.5845 0.5845
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0033 0.0057 0.0057
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.2642 0.4519
Echinococcus multilocularis dro:myosuppressin receptor 0.0069 0.0318 0.0318
Trypanosoma brucei cytochrome P450, putative 0.0039 0.0105 0.0105
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0119 0.0671 0.0671
Brugia malayi RNA, U transporter 1 0.0085 0.0428 0.0427
Entamoeba histolytica hypothetical protein 0.0049 0.0175 0.0466
Loa Loa (eye worm) TYRA-2 protein 0.0069 0.0318 0.0317
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0063 0.0272 0.1027
Trichomonas vaginalis conserved hypothetical protein 0.0067 0.0301 0.0798
Schistosoma mansoni hypothetical protein 0.0559 0.3798 0.6497
Giardia lamblia Kinase, CAMK CAMKL 0.0123 0.0698 0.185
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0379 0.2518 0.2517
Echinococcus granulosus cyclin dependent kinase 5 0.0109 0.0598 0.0598
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0009 0.0014
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0411 0.041
Echinococcus multilocularis cyclin t1 0.0025 0.0001 0.0001
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Onchocerca volvulus 0.0143 0.0843 0.3618
Trichomonas vaginalis CK1 family protein kinase 0.0098 0.0523 0.1386
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0069 0.0318 0.0542
Brugia malayi putative neuropeptide receptor 0.0069 0.0318 0.0317
Trichomonas vaginalis cyclin D, putative 0.0067 0.0301 0.0798
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0063 0.0272 0.1027
Echinococcus granulosus neuropeptides capa receptor 0.0069 0.0318 0.0318
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.1607 0.4263
Echinococcus multilocularis fmrfamide receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0268 0.173 0.1729
Trypanosoma brucei histone deacetylase 3 0.0226 0.1429 0.1429
Brugia malayi endochitinase 0.0179 0.1099 0.1098
Schistosoma mansoni neuropeptide receptor 0.0069 0.0318 0.0542
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0238 0.0406
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0069 0.0318 0.0318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0069 0.0318 0.0318
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0082 0.0411 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) neuropeptide F receptor 0.0069 0.0318 0.0317
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.1585 0.1585
Loa Loa (eye worm) chitinase I 0.016 0.0962 0.0961
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0095 0.0504 0.0504
Toxoplasma gondii histone deacetylase HDAC1 0.0226 0.1429 0.3792
Echinococcus granulosus lysine specific histone demethylase 1A 0.0063 0.0272 0.0272
Echinococcus multilocularis histone deacetylase 1 0.0251 0.1607 0.1607
Schistosoma mansoni gliotactin 0.0143 0.0843 0.144
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0079 0.0386 0.0386
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus granulosus casein kinase I alpha 0.0098 0.0523 0.0523
Onchocerca volvulus 0.0063 0.0272 0.1165
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0082 0.0411 0.0411
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0013 0.0033
Echinococcus multilocularis neuroligin 0.0143 0.0843 0.0843
Brugia malayi G-protein coupled receptor 0.0069 0.0318 0.0317
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis histone deacetylase 0.0226 0.1429 0.1429
Brugia malayi Protein kinase domain containing protein 0.0298 0.1945 0.1944
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0013 0.0013
Echinococcus multilocularis neuropeptide receptor 0.0069 0.0318 0.0318
Echinococcus multilocularis cyclin dependent kinase 9 0.0066 0.0297 0.0297
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0251 0.1607 0.4263
Entamoeba histolytica hypothetical protein 0.0076 0.0367 0.0974
Onchocerca volvulus 0.0031 0.0045 0.0189
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0037 0.0037
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0277 0.0277
Echinococcus multilocularis cyclin G2 0.0025 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis mitogen activated protein kinase 14 0.1431 1 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0838 0.5779 0.5779
Echinococcus multilocularis allatostatin A receptor 0.0069 0.0318 0.0318
Brugia malayi hypothetical protein 0.0026 0.0013 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0238
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0238 0.0238
Trypanosoma cruzi histone deacetylase, putative 0.0108 0.0591 0.0591
Entamoeba histolytica casein kinase 1, putative 0.0098 0.0523 0.1388
Echinococcus multilocularis histone deacetylase 6 0.0232 0.1475 0.1475
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0026 0.0013 0.0012
Echinococcus multilocularis mitogen activated protein kinase 11 0.1431 1 1
Schistosoma mansoni histone deacetylase 1 2 3 0.0108 0.0591 0.101
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Entamoeba histolytica protein kinase domain containing protein 0.0555 0.3768 1
Echinococcus granulosus serine:threonine protein kinase haspin 0.0559 0.3798 0.3798
Echinococcus granulosus Cell division cycle 2 protein kinase 0.0123 0.0698 0.0698
Schistosoma mansoni cyclins 0.0067 0.0301 0.0514
Brugia malayi G protein-coupled receptor 0.0069 0.0318 0.0317
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0045 0.0045
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0263 0.0449
Trypanosoma cruzi histone deacetylase 1, putative 0.0251 0.1607 0.1607
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0062 0.0263 0.0263
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0069 0.0318 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0109 0.0598 0.0597
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0119 0.0671 0.0671
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0075
Trypanosoma brucei cyclin 3 0.0025 0.0001 0.0001
Entamoeba histolytica cyclin, domain containing protein 0.0025 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Entamoeba histolytica cyclin, putative 0.0067 0.0301 0.08
Echinococcus granulosus serotonin receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus dro:myosuppressin receptor 0.0069 0.0318 0.0318
Echinococcus multilocularis somatostatin receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0216 0.1359 0.1358
Onchocerca volvulus 0.0069 0.0318 0.1361
Trichomonas vaginalis cyclins, putative 0.0077 0.037 0.0981
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.0904 0.1545
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0037 0.0097
Loa Loa (eye worm) hypothetical protein 0.0251 0.1607 0.1606
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0082 0.0411 0.041
Onchocerca volvulus 0.0058 0.0238 0.1021
Entamoeba histolytica protein kinase domain containing protein 0.0066 0.0297 0.0788
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0559 0.3798 0.3798
Loa Loa (eye worm) hypothetical protein 0.0847 0.5845 0.5844
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0123 0.0703 0.0703
Brugia malayi Protein kinase domain containing protein 0.0396 0.2642 0.2641
Onchocerca volvulus 0.0082 0.0411 0.1761
Echinococcus multilocularis Hepatocellular carcinoma associated antigen 59 0.0254 0.163 0.163
Trypanosoma cruzi mitotic cyclin, putative 0.0025 0.0001 0.0001
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0143 0.0143
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus multilocularis BC026374 protein (S09 family) 0.0143 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Echinococcus multilocularis serotonin receptor 0.0197 0.1224 0.1224
Brugia malayi hypothetical protein 0.0033 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus granulosus cyclin dependent kinase 0.0109 0.0598 0.0598
Brugia malayi Cyclin, N-terminal domain containing protein 0.0183 0.1129 0.1128
Leishmania major mitogen-activated protein kinase, putative,map kinase-like protein 0.0123 0.0698 0.0698
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni sodium/chloride dependent transporter 0.0058 0.0238 0.0406
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0049 0.0175 0.0175
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0082 0.0411 0.041
Leishmania major cyclin 9, putative 0.0025 0.0001 0.0001
Toxoplasma gondii hypothetical protein 0.0254 0.163 0.4323
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0671 0.1779
Chlamydia trachomatis protoporphyrinogen oxidase 0.0063 0.0272 1
Echinococcus multilocularis sex peptide receptor 0.0069 0.0318 0.0318
Echinococcus granulosus g protein coupled receptor 0.0069 0.0318 0.0318
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0069 0.0318 0.0542
Leishmania major protein kinase, putative 0.0033 0.0057 0.0057
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0143 0.0377
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0847 0.5845 1
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0281 0.0281
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Schistosoma mansoni aryl hydrocarbon receptor 0.0051 0.0188 0.0319
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0058 0.0238 0.0238
Onchocerca volvulus 0.0143 0.0843 0.3618
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0175 0.0175
Toxoplasma gondii histone deacetylase HDAC3 0.0251 0.1607 0.4263
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0109 0.0598 0.0597
Plasmodium falciparum transporter, putative 0.0058 0.0238 0.0899
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0082 0.0411 0.041
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0297 0.0506
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0001 0.0001
Onchocerca volvulus 0.0033 0.0061 0.0258
Echinococcus granulosus casein kinase I alpha 0.0098 0.0523 0.0523
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0069 0.0318 0.0318
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0892 0.6164 1
Plasmodium vivax histone deacetylase, putative 0.0226 0.1429 0.541
Loa Loa (eye worm) hypothetical protein 0.0247 0.1585 0.1584
Entamoeba histolytica hypothetical protein 0.0076 0.0367 0.0974
Echinococcus granulosus neuropeptide Y receptor 0.0069 0.0318 0.0318
Toxoplasma gondii hypothetical protein 0.0058 0.0238 0.0631
Echinococcus multilocularis neuropeptide FF receptor 2 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Onchocerca volvulus 0.0069 0.0318 0.1361
Brugia malayi Pre-SET motif family protein 0.0031 0.0045 0.0044
Trypanosoma cruzi histone deacetylase, putative 0.0226 0.1429 0.1429
Loa Loa (eye worm) carboxylesterase 0.0847 0.5845 0.5844
Schistosoma mansoni neurotransmitter gated ion channel 0.0049 0.0175 0.0299
Echinococcus granulosus serine:threonine protein kinase NLK 0.0123 0.0698 0.0698
Toxoplasma gondii histone deacetylase HDAC2 0.0251 0.1607 0.4263
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0025 0.0001 0.0001
Trichomonas vaginalis cyclins, putative 0.0119 0.0671 0.1778
Toxoplasma gondii histone deacetylase HDAC5 0.0108 0.0591 0.1567
Trypanosoma brucei mitotic cyclin 6 0.0119 0.0671 0.0671
Plasmodium vivax serine/threonine protein kinase KIN, putative 0.0123 0.0698 0.2639
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0076 0.0367 0.0367
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0396 0.2642 0.2641
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0411 0.0411
Schistosoma mansoni amine GPCR 0.0069 0.0318 0.0542
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0277 0.0303
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Onchocerca volvulus 0.0098 0.0523 0.2244
Echinococcus granulosus serine:threonine protein kinase haspin 0.0559 0.3798 0.3798
Loa Loa (eye worm) hypothetical protein 0.0503 0.3398 0.3397
Trypanosoma brucei histone deacetylase 2 0.0108 0.0591 0.0591
Loa Loa (eye worm) serotonin transporter b 0.0342 0.2257 0.2257
Trichomonas vaginalis cyclin B, putative 0.0119 0.0671 0.1778
Schistosoma mansoni neuroligin 3 (S09 family) 0.0143 0.0843 0.144
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0263 0.0263
Echinococcus multilocularis casein kinase i 0.0098 0.0523 0.0523
Trypanosoma cruzi Mitogen-activated protein kinase 10, putative 0.0123 0.0698 0.0698
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0598 0.1585
Trichomonas vaginalis cyclin B, putative 0.0119 0.0671 0.1778
Trichomonas vaginalis cyclin B, putative 0.0067 0.0301 0.0798
Brugia malayi Histone deacetylase family protein 0.0226 0.1429 0.1429
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0298 0.1945 0.1945
Onchocerca volvulus 0.0069 0.0318 0.1361
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus multilocularis neuropeptide Y receptor 0.0069 0.0318 0.0318
Trypanosoma cruzi cyclin, putative 0.0119 0.0671 0.0671
Brugia malayi Protein kinase domain containing protein 0.0109 0.0598 0.0597
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0123 0.0698 0.0697
Entamoeba histolytica protein kinase, putative 0.0298 0.1945 0.5161
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0033 0.0061 0.006
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0033 0.0061 0.006
Echinococcus granulosus histone deacetylase 6 0.0232 0.1475 0.1475
Echinococcus granulosus g protein coupled receptor 0.0069 0.0318 0.0318
Brugia malayi Protein kinase domain containing protein 0.0123 0.0698 0.0697
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni alpha-1 adrenergic receptor 0.0069 0.0318 0.0542
Mycobacterium ulcerans oxidoreductase 0.0063 0.0272 0.0294
Loa Loa (eye worm) haspin protein kinase 0.0559 0.3798 0.3797
Giardia lamblia Kinase, CK1 Casein kinase 0.0098 0.0523 0.1386
Loa Loa (eye worm) G-protein coupled receptor 0.0069 0.0318 0.0317
Schistosoma mansoni survival motor neuron protein 0.005 0.0185 0.0314
Echinococcus multilocularis serine:threonine protein kinase haspin 0.0559 0.3798 0.3798
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Echinococcus granulosus cyclin dependent kinase 9 0.0066 0.0297 0.0297
Echinococcus multilocularis histone deacetylase 7 0.0226 0.1429 0.1429
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Echinococcus multilocularis fmrfamide receptor 0.0069 0.0318 0.0318
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0099 0.0533 0.0532
Trypanosoma brucei dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0555 0.3768 0.3768
Loa Loa (eye worm) hypothetical protein 0.0119 0.0671 0.067
Brugia malayi Tachykinin-like peptides receptor 99D 0.0069 0.0318 0.0317
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0082 0.0411 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0098 0.0523 0.0523
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0298 0.1945 0.1945
Loa Loa (eye worm) histone deacetylase 7A 0.0226 0.1429 0.1429
Echinococcus multilocularis neuropeptide receptor A26 0.0069 0.0318 0.0318
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1431 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0143 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Schistosoma mansoni biogenic amine (5HT) receptor 0.0197 0.1224 0.2092
Brugia malayi Dual-specificity tyrosine-phosphorylation regulated kinase 2 0.0555 0.3768 0.3768
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0082 0.0411 0.0411
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0109 0.0598 0.0598
Giardia lamblia Kinase, CMGC CDK 0.0109 0.0598 0.1585
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0238
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0116 0.0437
Brugia malayi Protein kinase domain containing protein 0.0352 0.2328 0.2327
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0277 0.0303
Schistosoma mansoni serine/threonine protein kinase 0.0098 0.0523 0.0894
Leishmania major serine/threonine kinase-like protein, putative 0.0123 0.0698 0.0698
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Onchocerca volvulus 0.0058 0.0238 0.1021
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0033 0.0061 0.0061
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0069 0.0318 0.0542
Trypanosoma cruzi mitotic cyclin, putative 0.0025 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0936 0.6478 0.6478
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.1585 0.1585
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trypanosoma cruzi histone deacetylase, putative 0.0108 0.0591 0.0591
Schistosoma mansoni hypothetical protein 0.0254 0.163 0.2787
Echinococcus granulosus cyclin 0.0095 0.0504 0.0504
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Plasmodium vivax hypothetical protein, conserved 0.0063 0.0272 0.1027
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0033 0.0057 0.0057
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0082 0.0411 0.041
Schistosoma mansoni biogenic amine receptor 0.0069 0.0318 0.0542
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0238 0.0238
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus multilocularis g protein coupled receptor 0.0069 0.0318 0.0318
Brugia malayi G-protein coupled receptor 0.0069 0.0318 0.0317
Echinococcus granulosus dual specificity 0.0555 0.3768 0.3768
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0069 0.0318 0.0542
Loa Loa (eye worm) hypothetical protein 0.0254 0.163 0.1629
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0128 0.0737 0.0736
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0033 0.0061 0.006
Leishmania major histone deacetylase, putative 0.0226 0.1429 0.1429
Onchocerca volvulus 0.0069 0.0318 0.1361
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0183 0.1129 0.1129
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0396 0.2642 0.2642
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0119 0.0671 0.067
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0119 0.0671 0.0671
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0109 0.0598 0.0598
Toxoplasma gondii casein kinase I 0.0098 0.0523 0.1386
Onchocerca volvulus 0.0082 0.0411 0.1761
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trypanosoma cruzi cyclin 6, putative 0.0119 0.0671 0.0671
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus granulosus cyclins 0.0067 0.0301 0.0301
Echinococcus granulosus cyclins 0.0067 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Toxoplasma gondii hypothetical protein 0.0042 0.0126 0.0333
Echinococcus multilocularis histone deacetylase 8 0.0108 0.0591 0.0591
Loa Loa (eye worm) cyclin domain-containing protein 0.0183 0.1129 0.1128
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Entamoeba histolytica cyclin, domain containing protein 0.0025 0.0001 0.0002
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0033 0.0061 0.006
Echinococcus multilocularis serotonin transporter 0.0342 0.2257 0.2257
Onchocerca volvulus 0.0082 0.0411 0.1761
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Loa Loa (eye worm) hypothetical protein 0.0342 0.2257 0.2257
Plasmodium vivax protein kinase Crk2 0.0109 0.0598 0.2262
Echinococcus granulosus cyclin G2 0.0025 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Echinococcus multilocularis neuropeptide Y receptor 0.0069 0.0318 0.0318
Plasmodium falciparum histone deacetylase, putative 0.0226 0.1429 0.541
Trypanosoma brucei cdc2-related kinase 1 0.0109 0.0598 0.0598
Entamoeba histolytica casein kinase, putative 0.0098 0.0523 0.1388
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0411 0.0411
Plasmodium falciparum MO15-related protein kinase 0.0123 0.0698 0.2639
Echinococcus granulosus nAChR subunit 0.0082 0.0411 0.0411
Trypanosoma brucei casein kinase I, isoform 2 0.0098 0.0523 0.0523
Onchocerca volvulus Nischarin homolog 0.0216 0.1359 0.5837
Schistosoma mansoni opsin-like receptor 0.0069 0.0318 0.0542
Echinococcus granulosus alpha 1A adrenergic receptor 0.0069 0.0318 0.0318
Echinococcus multilocularis sodium and chloride dependent glycine 0.0058 0.0238 0.0238
Brugia malayi Dopamine receptor protein 2 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0063 0.0272 0.1027
Onchocerca volvulus 0.0342 0.2257 0.9697
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Mycobacterium tuberculosis Possible chitinase 0.0136 0.0795 0.096
Schistosoma mansoni histone deacetylase 4 5 0.0226 0.1429 0.2445
Trichomonas vaginalis CK1 family protein kinase 0.0098 0.0523 0.1386
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0069 0.0318 0.0317
Echinococcus multilocularis cyclin A3 4 0.0025 0.0001 0.0001
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Leishmania major chitinase 0.016 0.0962 0.0962
Echinococcus granulosus dual specificity protein kinase clk2 0.0396 0.2642 0.2642
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0411 0.0411
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0025 0.0003 0.0003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) hypothetical protein 0.0031 0.0045 0.0044
Onchocerca volvulus Putative nachr subunit 0.0082 0.0411 0.1761
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus granulosus geminin 0.0175 0.107 0.107
Schistosoma mansoni neuropeptide receptor 0.0069 0.0318 0.0542
Echinococcus multilocularis cyclin y 0.0025 0.0001 0.0001
Echinococcus multilocularis nAChR subunit 0.0082 0.0411 0.0411
Echinococcus granulosus 7tm_1 domain containing protein 0.0069 0.0318 0.0318
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0045 0.0075
Echinococcus granulosus neuropeptide receptor A26 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0224 0.0223
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0058 0.0238 0.0238
Brugia malayi G protein-coupled receptor F59B2.13 0.0069 0.0318 0.0317
Echinococcus multilocularis para nitrobenzyl esterase 0.0143 0.0843 0.0843
Brugia malayi hypothetical protein 0.0076 0.0367 0.0366
Loa Loa (eye worm) histone deacetylase 0.0226 0.1429 0.1429
Schistosoma mansoni transcription factor LCR-F1 0.0076 0.0367 0.0626
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Schistosoma mansoni sodium/chloride dependent transporter 0.0077 0.0376 0.0642
Schistosoma mansoni BC026374 protein (S09 family) 0.0143 0.0843 0.144
Onchocerca volvulus 0.0069 0.0318 0.1361
Echinococcus multilocularis neuropeptide s receptor 0.0069 0.0318 0.0318
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0143 0.0843 0.144
Trichomonas vaginalis CMGC family protein kinase 0.0555 0.3768 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus multilocularis cyclin 0.0095 0.0504 0.0504
Onchocerca volvulus Putative endochitinase 0.016 0.0962 0.413
Echinococcus granulosus serine:threonine protein kinase haspin 0.0559 0.3798 0.3798
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175
Trypanosoma cruzi cdc2-related kinase 3 0.0109 0.0598 0.0598
Mycobacterium ulcerans chitinase/cellulase 0.0136 0.0795 0.1155
Echinococcus granulosus mitogen activated protein kinase 15 0.0123 0.0698 0.0698
Giardia lamblia Hypothetical protein 0.0067 0.0301 0.0798
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Schistosoma mansoni amine oxidase 0.0063 0.0272 0.0464
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0847 0.5845 0.5844
Echinococcus multilocularis casein kinase I alpha 0.0098 0.0523 0.0523
Onchocerca volvulus 0.0069 0.0318 0.1361
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0033 0.0061 0.006
Schistosoma mansoni histone deacetylase 0.0251 0.1607 0.2748
Loa Loa (eye worm) hypothetical protein 0.0143 0.0843 0.0842
Echinococcus multilocularis neuropeptides capa receptor 0.0069 0.0318 0.0318
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0082 0.0411 0.0411
Giardia lamblia Kinase, CMGC CDK 0.0109 0.0598 0.1585
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0119 0.0671 0.0671
Brugia malayi PAS domain containing protein 0.0051 0.0188 0.0187
Schistosoma mansoni sodium/chloride dependent transporter 0.0342 0.2257 0.3861
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Plasmodium vivax glycogen synthase kinase 3, putative 0.0119 0.0671 0.2538
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0013 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0281 0.0309
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0062 0.0263 0.0263
Onchocerca volvulus Histone deacetylase 10 homolog 0.0108 0.0591 0.2537
Schistosoma mansoni nAChR subunit 0.0033 0.0061 0.0103
Plasmodium falciparum protein serine/threonine kinase-1 0.0396 0.2642 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0143 0.0843 0.2234
Echinococcus granulosus importin subunit beta 1 0.003 0.0037 0.0037
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0379 0.2518 0.2517
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0058 0.0238 0.0238
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.0063 0.0272 0.0464
Echinococcus multilocularis histone deacetylase 6 0.0226 0.1429 0.1429
Schistosoma mansoni neuropeptide receptor 0.0069 0.0318 0.0542
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trichomonas vaginalis CMGC family protein kinase 0.0109 0.0598 0.1585
Trypanosoma cruzi cdc2-related kinase 1 0.0109 0.0598 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus multilocularis protein kinase shaggy 0.0119 0.0671 0.0671
Brugia malayi Endochitinase 0.0179 0.1099 0.1098
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0069 0.0318 0.0318
Schistosoma mansoni cyclin B3 0.0183 0.1129 0.1931
Trichomonas vaginalis cyclins, putative 0.0119 0.0671 0.1778
Onchocerca volvulus 0.0254 0.163 0.6999
Schistosoma mansoni single-minded 0.0051 0.0188 0.0319
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0058 0.0238 0.0406
Echinococcus granulosus peptide allatostatin:somatostatin 0.0069 0.0318 0.0318
Schistosoma mansoni acetylcholinesterase 0.0143 0.0843 0.144
Echinococcus granulosus serotonin transporter 0.0342 0.2257 0.2257
Schistosoma mansoni hypothetical protein 0.0069 0.0318 0.0542
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Onchocerca volvulus 0.0082 0.0411 0.1761
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0342 0.2257 0.2257
Schistosoma mansoni hypothetical protein 0.0175 0.107 0.1829
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0411 0.041
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Trypanosoma cruzi dual specificity tyrosine-phosphorylation-regulated kinase 2, putative 0.0555 0.3768 0.3768
Echinococcus granulosus neuropeptide receptor 0.0069 0.0318 0.0318
Mycobacterium tuberculosis Carboxylesterase LipT 0.0143 0.0843 0.1048
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0352 0.2328 0.2327
Schistosoma mansoni biogenic amine (5HT) receptor 0.0463 0.3118 0.5334
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Loa Loa (eye worm) norepinephrine transporter 0.0342 0.2257 0.2257
Echinococcus granulosus cyclin y 0.0025 0.0001 0.0001
Giardia lamblia Kinase, CAMK CAMKL 0.0123 0.0698 0.185
Echinococcus granulosus histone deacetylase 6 0.0226 0.1429 0.1429
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Schistosoma mansoni jumonji/arid domain-containing protein 0.0062 0.0263 0.0449
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Echinococcus granulosus cyclin b3 0.0067 0.0301 0.0301
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0183 0.1129 0.1129
Brugia malayi hypothetical protein 0.0063 0.0272 0.0271
Loa Loa (eye worm) CMGC/DYRK/DYRK2 protein kinase 0.0555 0.3768 0.3768
Schistosoma mansoni serine/threonine kinase 0.0123 0.0698 0.1193
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0063 0.0272 0.5
Trichomonas vaginalis cyclin B, putative 0.0119 0.0671 0.1778
Brugia malayi Cyclin, N-terminal domain containing protein 0.0162 0.0976 0.0975
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0116 0.0306
Loa Loa (eye worm) hypothetical protein 0.0342 0.2257 0.2257
Echinococcus multilocularis cyclin G2 0.0025 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Schistosoma mansoni hypothetical protein 0.0318 0.2086 0.3567
Loa Loa (eye worm) histone deacetylase 1 0.0251 0.1607 0.1606
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0082 0.0411 0.0701
Trypanosoma cruzi histone deacetylase, putative 0.0226 0.1429 0.1429
Onchocerca volvulus 0.0119 0.0671 0.2881
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0109 0.0598 0.1585
Leishmania major protein kinase, putative 0.0396 0.2642 0.2642
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Plasmodium falciparum histone deacetylase 2 0.0226 0.1429 0.541
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0069 0.0318 0.0542
Schistosoma mansoni sodium-dependent amino acid transporter 0.0058 0.0238 0.0406
Trypanosoma cruzi cdc2-related kinase 1 0.0109 0.0598 0.0598
Echinococcus granulosus nAChR subunit 0.0049 0.0175 0.0175
Brugia malayi Cation transporter family protein 0.0082 0.0411 0.041
Echinococcus granulosus tm gpcr rhodopsin 0.0936 0.6478 0.6478
Echinococcus multilocularis cyclin dependent kinase 0.0109 0.0598 0.0598
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0033 0.0057 0.0057
Echinococcus granulosus neuropeptide receptor 0.0069 0.0318 0.0318
Onchocerca volvulus 0.0082 0.0411 0.1761
Schistosoma mansoni hypothetical protein 0.0175 0.107 0.1829
Echinococcus multilocularis cyclin y 0.0025 0.0001 0.0001
Schistosoma mansoni neuropeptide F-like receptor 0.0069 0.0318 0.0542
Echinococcus multilocularis acetylcholinesterase 0.0847 0.5845 0.5845
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Brugia malayi Dopamine receptor 0.0069 0.0318 0.0317
Echinococcus granulosus lysine specific demethylase 5A 0.0062 0.0263 0.0263
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0058 0.0238 0.0238
Schistosoma mansoni adenoreceptor 0.0069 0.0318 0.0542
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0829 0.5717 1
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0058 0.0238 0.0238
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0143 0.0537
Echinococcus granulosus dual specificity 0.0298 0.1945 0.1945
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0049 0.0175 0.0175
Onchocerca volvulus 0.0254 0.163 0.6999
Trypanosoma cruzi serine/threonine protein kinase, putative 0.0123 0.0698 0.0698
Plasmodium vivax histone deacetylase, putative 0.0108 0.0591 0.2236
Echinococcus granulosus single minded 2 0.0038 0.0094 0.0094
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Echinococcus granulosus BC026374 protein S09 family 0.0143 0.0843 0.0843
Loa Loa (eye worm) hypothetical protein 0.0124 0.071 0.0709
Toxoplasma gondii histone lysine-specific demethylase 0.0063 0.0272 0.072
Entamoeba histolytica cyclin family protein 0.0067 0.0301 0.08
Brugia malayi hypoxia-induced factor 1 0.0158 0.0946 0.0945
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0352 0.2328 0.2327
Brugia malayi cell division control protein 2 homolog 0.0109 0.0598 0.0597
Schistosoma mansoni serine/threonine protein kinase 0.0396 0.2642 0.4519
Echinococcus multilocularis neuropeptides capa receptor 0.0069 0.0318 0.0318
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0025 0.0001 0.0001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0033 0.0061 0.006
Trichomonas vaginalis cyclin A, putative 0.0119 0.0671 0.1778
Brugia malayi Carboxylesterase family protein 0.0143 0.0843 0.0842
Brugia malayi bHLH-PAS transcription factor 0.0038 0.0094 0.0093
Entamoeba histolytica hypothetical protein 0.0025 0.0001 0.0002
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0069 0.0318 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Brugia malayi Hepatocellular carcinoma-associated antigen 59 family protein 0.0254 0.163 0.1629
Echinococcus multilocularis geminin 0.0175 0.107 0.107
Plasmodium vivax importin-beta 2, putative 0.003 0.0037 0.0138
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Brugia malayi Carboxylesterase family protein 0.0847 0.5845 0.5844
Echinococcus granulosus cyclin dependent kinase 1 0.0109 0.0598 0.0598
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Mycobacterium ulcerans dehydrogenase 0.0063 0.0272 0.0294
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0082 0.0411 0.0411
Brugia malayi Cytochrome P450 family protein 0.004 0.0112 0.0111
Echinococcus granulosus cyclin G2 0.0025 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0082 0.0411 0.041
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0411 0.0411
Loa Loa (eye worm) neuropeptide F receptor 0.0069 0.0318 0.0317
Trichomonas vaginalis cyclin B3, putative 0.0067 0.0301 0.0798
Plasmodium falciparum protein kinase 5 0.0109 0.0598 0.2262
Schistosoma mansoni protein kinase 0.0098 0.0523 0.0894
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Echinococcus multilocularis dual specificity 0.0555 0.3768 0.3768
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0123 0.0703 0.0703
Trypanosoma cruzi UDP-galactopyranose mutase 0.0063 0.0272 0.0272
Echinococcus granulosus sodium and chloride dependent glycine 0.0058 0.0238 0.0238
Brugia malayi histone deacetylase 1 (HD1) 0.0251 0.1607 0.1606
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0063 0.0272 0.0464
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0238
Onchocerca volvulus 0.005 0.0185 0.0789
Schistosoma mansoni hypothetical protein 0.0103 0.056 0.0958
Onchocerca volvulus 0.0069 0.0318 0.1361
Onchocerca volvulus 0.0069 0.0318 0.1361
Brugia malayi GSG2 0.0559 0.3798 0.3797
Echinococcus granulosus nischarin 0.0221 0.1396 0.1396
Loa Loa (eye worm) CYP4Cod1 0.0039 0.0105 0.0104
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0082 0.0411 0.0411
Plasmodium falciparum amino acid transporter, putative 0.0058 0.0238 0.0899
Brugia malayi metabotropic glutamate receptor type 2 0.0026 0.0009 0.0008
Echinococcus multilocularis cyclin dependent kinase 9 0.017 0.1032 0.1032
Onchocerca volvulus Putative endochitinase 0.0179 0.1099 0.4719
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0033 0.0061 0.0061
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus multilocularis mitogen activated protein kinase 14 0.1431 1 1
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0037 0.0037
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0105 0.0104
Echinococcus granulosus G1:S specific cyclin D1 0.0025 0.0001 0.0001
Trypanosoma brucei histone deacetylase 4 0.0226 0.1429 0.1429
Schistosoma mansoni jumonji domain containing protein 0.0062 0.0263 0.0449
Schistosoma mansoni acetylcholine receptor subunit beta 0.0033 0.0061 0.0103
Echinococcus multilocularis nischarin 0.0221 0.1396 0.1396
Loa Loa (eye worm) microfilarial chitinase 0.0156 0.0932 0.0931
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0463 0.3118 0.3118
Schistosoma mansoni kinase 0.0066 0.0297 0.0506
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Loa Loa (eye worm) cyclin C 0.0095 0.0504 0.0503
Echinococcus granulosus histone deacetylase 6 0.0226 0.1429 0.1429
Echinococcus multilocularis G1:S specific cyclin D1 0.0025 0.0001 0.0001
Trypanosoma cruzi cdc2-related kinase 3 0.0109 0.0598 0.0598
Echinococcus granulosus histone deacetylase 8 0.0108 0.0591 0.0591
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0411 0.041
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0033 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0069 0.0318 0.0317
Echinococcus granulosus neuropeptide FF receptor 2 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0058 0.0238 0.0238
Trichomonas vaginalis cyclins, putative 0.0119 0.0671 0.1778
Schistosoma mansoni hypothetical protein 0.0069 0.0318 0.0542
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0109 0.0598 0.0597
Brugia malayi jmjC domain containing protein 0.0062 0.0263 0.0262
Mycobacterium ulcerans carboxylesterase, LipT 0.0143 0.0843 0.1234
Schistosoma mansoni amine GPCR 0.0069 0.0318 0.0542
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0119 0.0671 0.0671
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0298 0.1945 0.1945
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.0904 0.0903
Brugia malayi neuropeptide F receptor 0.0069 0.0318 0.0317
Loa Loa (eye worm) acetylcholine receptor protein 0.0033 0.0061 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Onchocerca volvulus 0.0038 0.0094 0.0398
Schistosoma mansoni growth hormone secretagogue receptor 0.0069 0.0318 0.0542
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0342 0.2257 0.3861
Brugia malayi Carboxylesterase family protein 0.0143 0.0843 0.0842
Giardia lamblia Kinase, CMGC GSK 0.0119 0.0671 0.1779
Echinococcus multilocularis 0.0377 0.2504 0.2504
Trypanosoma cruzi UDP-galactopyranose mutase 0.0063 0.0272 0.0272
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Leishmania major mitotic cyclin, putative 0.0025 0.0001 0.0001
Echinococcus multilocularis g-protein coupled receptor 0.0069 0.0318 0.0318
Echinococcus multilocularis serine:threonine protein kinase NLK 0.0123 0.0698 0.0698
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Echinococcus multilocularis cyclins 0.0067 0.0301 0.0301
Entamoeba histolytica protein kinase domain containing protein 0.0119 0.0671 0.1781
Echinococcus granulosus rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0063 0.0272 0.0271
Schistosoma mansoni nAChR subunit 0.0082 0.0411 0.0701
Echinococcus multilocularis rhodopsin orphan GPCR 0.0069 0.0318 0.0318
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0396 0.2642 0.2642
Echinococcus multilocularis casein kinase I delta 0.0098 0.0523 0.0523
Loa Loa (eye worm) melatonin receptor type 1A 0.0069 0.0318 0.0317
Brugia malayi Cytochrome P450 family protein 0.0039 0.0105 0.0104
Onchocerca volvulus 0.0069 0.0318 0.1361
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0033 0.0061 0.0061
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0069 0.0318 0.0317
Trichomonas vaginalis histone deacetylase, putative 0.0251 0.1607 0.4263
Loa Loa (eye worm) hypothetical protein 0.0279 0.1807 0.1807
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1431 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0049 0.0175 0.0299
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0396 0.2642 0.2642
Brugia malayi casein kinase 1, delta 0.0098 0.0523 0.0522
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0069 0.0318 0.0318
Loa Loa (eye worm) hypothetical protein 0.0197 0.1224 0.1223
Giardia lamblia G2/mitotic-specific cyclin B 0.0119 0.0671 0.1778
Loa Loa (eye worm) cuticular endochitinase 0.016 0.0962 0.0961
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Toxoplasma gondii hypothetical protein 0.0058 0.0238 0.0631
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0119 0.0671 0.067
Brugia malayi follicle stimulating hormone receptor 0.0069 0.0318 0.0317
Plasmodium vivax cyclin dependent kinase 7 (cdk7), putative 0.0123 0.0698 0.2639
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0411 0.0411
Echinococcus multilocularis G protein coupled receptor 139 0.0069 0.0318 0.0318
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0058 0.0238 0.0238
Echinococcus granulosus histone deacetylase 7 0.0226 0.1429 0.1429
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0058 0.0238 0.0406
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0281 0.048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0069 0.0318 0.0542
Echinococcus granulosus casein kinase I delta 0.0098 0.0523 0.0523
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0143 0.0843 0.1048
Onchocerca volvulus Putative endochitinase 0.016 0.0962 0.413
Trichomonas vaginalis AGC family protein kinase 0.0123 0.0698 0.185
Brugia malayi Histone deacetylase family protein 0.0226 0.1429 0.1429
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0109 0.0598 0.0598
Brugia malayi endochitinase 0.016 0.0962 0.0961
Trichomonas vaginalis CMGC family protein kinase 0.0123 0.0698 0.185
Schistosoma mansoni protein kinase 0.0123 0.0698 0.1193
Loa Loa (eye worm) hypothetical protein 0.0033 0.0061 0.006
Onchocerca volvulus 0.0049 0.0175 0.075
Plasmodium falciparum cyclin 0.0067 0.0301 0.1138
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.0904 0.0904
Echinococcus multilocularis cyclin dependent kinase 7 0.0099 0.0533 0.0533
Echinococcus granulosus mitogen activated protein kinase 11 0.1431 1 1
Brugia malayi Cyclin C 0.0095 0.0504 0.0503
Trichomonas vaginalis CAMK family protein kinase 0.0123 0.0698 0.185
Trichomonas vaginalis serine/threonine kinase, putative 0.0123 0.0698 0.185
Echinococcus granulosus histone acetyltransferase KAT2B 0.0147 0.0874 0.0874
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0533 0.091
Trichomonas vaginalis CMGC family protein kinase 0.0119 0.0671 0.1779
Leishmania major hypothetical protein, conserved 0.0026 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0082 0.0411 0.041
Echinococcus granulosus carboxylesterase 5A 0.0847 0.5845 0.5845
Echinococcus multilocularis serotonin receptor 0.0197 0.1224 0.1224
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0039 0.0105 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0352 0.2328 0.3982
Brugia malayi neuropeptide F receptor 0.0069 0.0318 0.0317
Brugia malayi hypothetical protein 0.0069 0.0318 0.0317
Trypanosoma cruzi cytochrome P450, putative 0.0039 0.0105 0.0105
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0013 0.0046
Entamoeba histolytica cyclin family protein 0.0067 0.0301 0.08
Loa Loa (eye worm) hypothetical protein 0.0049 0.0175 0.0175

Activities

Activity type Activity value Assay description Source Reference
IVP (functional) = 32 Integrated vasodilating potency (IVP) (the product of compound-induced maximum percent decrease in the perfusion pressure and the duration of the effect in minutes at 100 ug (ia)) ChEMBL. 7401118

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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