Detailed information for compound 607854

Basic information

Technical information
  • TDR Targets ID: 607854
  • Name: ethyl 1-(2-methyl-4,9-dioxobenzo[f][1]benzoxo le-3-carbonyl)piperidine-4-carboxylate
  • MW: 395.405 | Formula: C22H21NO6
  • H donors: 0 H acceptors: 4 LogP: 2.84 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1CCN(CC1)C(=O)c1c(C)oc2c1C(=O)c1ccccc1C2=O
  • InChi: 1S/C22H21NO6/c1-3-28-22(27)13-8-10-23(11-9-13)21(26)16-12(2)29-20-17(16)18(24)14-6-4-5-7-15(14)19(20)25/h4-7,13H,3,8-11H2,1-2H3
  • InChiKey: YCQRDSJRASINSW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • ethyl 1-(2-methyl-4,9-dioxo-benzo[f]benzofuran-3-carbonyl)piperidine-4-carboxylate
  • 1-[(2-methyl-4,9-dioxo-3-benzo[f]benzofuranyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester
  • 1-(4,9-diketo-2-methyl-benzo[f]benzofuran-3-carbonyl)isonipecotic acid ethyl ester
  • ethyl 1-(2-methyl-4,9-dioxo-benzo[f][1]benzoxol-3-yl)carbonylpiperidine-4-carboxylate
  • MLS000724686
  • SMR000237575
  • ZINC00937963
  • T5466319

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. Starlite/ChEMBL No references
Homo sapiens muscleblind-like splicing regulator 1 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references
Giardia intestinalis Putative fructose-1,6-bisphosphate aldolase Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB Starlite/ChEMBL No references
Homo sapiens Rap guanine nucleotide exchange factor (GEF) 3 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Brugia malayi Muscleblind-like protein Get druggable targets OG5_132352 All targets in OG5_132352
Brugia malayi N-terminal motif family protein Get druggable targets OG5_131726 All targets in OG5_131726
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Mycobacterium ulcerans replicative DNA helicase DnaB Get druggable targets OG5_131890 All targets in OG5_131890
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_131726 All targets in OG5_131726
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis muscleblind protein 1 Get druggable targets OG5_132352 All targets in OG5_132352
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog Get druggable targets OG5_131726 All targets in OG5_131726
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis muscleblind protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Wolbachia endosymbiont of Brugia malayi recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum replicative DNA helicase (dnaB) Get druggable targets OG5_131890 All targets in OG5_131890
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB Get druggable targets OG5_131890 All targets in OG5_131890
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Chlamydia trachomatis replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Chlamydia trachomatis recombinase RecA Get druggable targets OG5_130095 All targets in OG5_130095
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum fructose-bisphosphate aldolase Get druggable targets OG5_129214 All targets in OG5_129214
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum recombinase A Get druggable targets OG5_130095 All targets in OG5_130095
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. Get druggable targets OG5_130095 All targets in OG5_130095
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni Replicative DNA helicase Get druggable targets OG5_131890 All targets in OG5_131890
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132352 All targets in OG5_132352
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. Get druggable targets OG5_130095 All targets in OG5_130095
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis fructose-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative Get druggable targets OG5_129214 All targets in OG5_129214
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.5 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 25.8 %
Candida albicans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 358 aa 22.6 %
Mycobacterium ulcerans fructose-bisphosphate aldolase Putative fructose-1,6-bisphosphate aldolase   323 aa 361 aa 26.9 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni serine/threonine protein kinase 0.00706599 0.015597 0.0155427
Leishmania major hypothetical protein, conserved 0.00368632 0.00469944 0.00691131
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0030568 0.0026696 0.00357031
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Giardia lamblia Cathepsin B precursor 0.0426756 0.130418 0.266528
Brugia malayi cyclin fold protein 1 variant b 0.0062898 0.0130942 0.0130398
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Plasmodium falciparum tubulin beta chain 0.0237345 0.0693438 0.118697
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Loa Loa (eye worm) hypothetical protein 0.00279123 0.00181326 0.00131349
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cathepsin L cysteine proteinase 0.182258 0.580494 0.580284
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.00811809 0.0189894 0.0304318
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0350178 0.105726 0.105279
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0297584 0.0887674 0.0887172
Echinococcus granulosus tyrosine protein kinase Lyn 0.00835651 0.0197582 0.0192674
Brugia malayi P38 map kinase family protein 2 0.0124779 0.0330476 0.0329942
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.00569812 0.0111864 0.0184243
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.00462738 0.00773384 0.00767909
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Cytochrome P450 family protein 0.00278484 0.00179267 0.00173759
Echinococcus multilocularis SWI:SNF matrix associated 0.00618448 0.0127546 0.0122604
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Giardia lamblia Cyclin fold protein 1, putative 0.0062898 0.0130942 0.0258362
Brugia malayi cathepsin L-like precursor 0.12567 0.398031 0.397998
Entamoeba histolytica cysteine proteinase 2 0.099263 0.312881 0.538992
Loa Loa (eye worm) neuropeptide F receptor 0.0350178 0.105726 0.105279
Schistosoma mansoni serine/threonine protein kinase 0.0030568 0.0026696 0.00261457
Loa Loa (eye worm) AUR protein kinase 0.0101101 0.0254124 0.0249245
Schistosoma mansoni serine/threonine protein kinase 0.00426539 0.00656665 0.00651183
Plasmodium vivax serine-repeat antigen (SERA) 0.0426756 0.130418 0.223999
Onchocerca volvulus 0.00480698 0.00831297 0.0134988
Schistosoma mansoni tyrosine kinase 0.0326182 0.0979889 0.0979391
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Echinococcus multilocularis adam 0.00363952 0.00454854 0.00405014
Brugia malayi Protein kinase domain containing protein 0.0107418 0.0274494 0.0273957
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.00368632 0.00469944 0.00723974
Echinococcus granulosus ephrin type A receptor 4 A 0.00461762 0.00770239 0.00720556
Schistosoma mansoni hypothetical protein 0.00266606 0.00140966 0.00135456
Brugia malayi Carboxylesterase family protein 0.0114839 0.0298423 0.0297887
Echinococcus multilocularis thyroid hormone receptor alpha 0.00464976 0.00780602 0.00730925
Trypanosoma brucei protein kinase A regulatory subunit 0.00368632 0.00469944 0.00691131
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.00372914 0.00483753 0.00433927
Trichomonas vaginalis AGC family protein kinase 0.00441872 0.00706103 0.0113115
Mycobacterium ulcerans hypothetical protein 0.00368632 0.00469944 0.10363
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.00269638 0.00150744 0.00100751
Leishmania major cyclic nucleotide-binding protein-like protein 0.00368632 0.00469944 0.00691131
Echinococcus multilocularis sex peptide receptor 0.0350178 0.105726 0.105279
Giardia lamblia 5-AMP-activated protein kinase, beta-1 subunit 0.00324397 0.00327312 0.00568817
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.026092 0.0769454 0.0764833
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Schistosoma mansoni cathepsin s 0.0565873 0.175276 0.175231
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.00603699 0.0122791 0.0117845
Echinococcus multilocularis tubulin subunit beta 0.0237345 0.0693438 0.0688779
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Echinococcus granulosus tyrosine protein kinase ABL1 0.0221958 0.0643824 0.063914
Echinococcus granulosus tachykinin peptides receptor 99D 0.0350178 0.105726 0.105279
Loa Loa (eye worm) cathepsin B 0.153556 0.487948 0.487691
Chlamydia trachomatis serine/threonine protein kinase 0.0142865 0.0388794 0.406575
Echinococcus granulosus cyclin t1 0.0062898 0.0130942 0.0126001
Brugia malayi Protein kinase domain containing protein 0.00480698 0.00831297 0.00825825
Entamoeba histolytica cysteine proteinase, putative 0.099263 0.312881 0.538992
Loa Loa (eye worm) hypothetical protein 0.00950888 0.023474 0.0229851
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.00324397 0.00327312 0.00321812
Loa Loa (eye worm) hypothetical protein 0.00368632 0.00469944 0.00420111
Brugia malayi phosphoinositide-dependent protein kinase I 0.00388268 0.0053326 0.00527771
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114839 0.0298423 0.0297887
Plasmodium vivax aspartyl proteinase, putative 0.0383289 0.116403 0.199834
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0350178 0.105726 0.105279
Plasmodium vivax protein kinase Crk2 0.00706599 0.015597 0.0260289
Trypanosoma cruzi CYC2-like cyclin, putative 0.0491228 0.151207 0.150782
Loa Loa (eye worm) hypothetical protein 0.00768843 0.0176041 0.0171122
Trypanosoma cruzi beta tubulin, putative 0.0237345 0.0693438 0.0688779
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.00569812 0.0111864 0.0111319
Loa Loa (eye worm) CDC7 protein kinase 0.00480698 0.00831297 0.00781645
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Entamoeba histolytica PH domain containing protein kinase, putative 0.00327259 0.00336539 0.00579746
Loa Loa (eye worm) aspartic protease BmAsp-1 0.00950888 0.023474 0.0229851
Mycobacterium ulcerans carboxylesterase, LipT 0.0114839 0.0298423 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.099263 0.312881 0.538594
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Trichomonas vaginalis CMGC family protein kinase 0.0057134 0.0112357 0.0185092
Loa Loa (eye worm) hypothetical protein 0.04587 0.140718 0.140288
Entamoeba histolytica cell division protein kinase 2, putative 0.00760203 0.0173255 0.0298461
Echinococcus granulosus neuropeptide receptor 0.0350178 0.105726 0.105279
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.00388268 0.0053326 0.00483458
Echinococcus granulosus SWI:SNF matrix associated 0.00618448 0.0127546 0.0122604
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Toxoplasma gondii cyclin 4, putative 0.0062898 0.0130942 0.0217137
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0855307 0.268603 0.268236
Plasmodium vivax hypothetical protein, conserved 0.0062898 0.0130942 0.0217137
Echinococcus multilocularis tyrosine protein kinase shark 0.00358585 0.00437548 0.00387698
Onchocerca volvulus Neuropeptide F receptor homolog 0.0350178 0.105726 0.18145
Echinococcus granulosus glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Trichomonas vaginalis adenylate cyclase type III, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis AGC family protein kinase 0.00551764 0.0106045 0.0174209
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.00251948 0.000937031 0.000752763
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Brugia malayi Protein kinase domain containing protein 0.00551764 0.0106045 0.0105499
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057134 0.0112357 0.0107406
Brugia malayi Melatonin receptor type 1A 0.0350178 0.105726 0.105677
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0350178 0.105726 0.105677
Brugia malayi serine/threonine kinase 12 0.0101101 0.0254124 0.0253587
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Schistosoma mansoni protein kinase 0.0101101 0.0254124 0.0253587
Loa Loa (eye worm) hypothetical protein 0.00850189 0.020227 0.0197364
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0260058 0.0766673 0.076205
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0315703 0.0946098 0.0941565
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.00269638 0.00150744 0.00100751
Echinococcus multilocularis patatin phospholipase domain containing protein 0.00368632 0.00469944 0.00420111
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.00551764 0.0106045 0.0101091
Brugia malayi Protein kinase domain containing protein 0.00388268 0.0053326 0.00527771
Loa Loa (eye worm) hypothetical protein 0.00950888 0.023474 0.0229851
Loa Loa (eye worm) cyclin domain-containing protein 0.0062898 0.0130942 0.0126001
Giardia lamblia Aurora kinase 0.0101101 0.0254124 0.0511071
Loa Loa (eye worm) hypothetical protein 0.00768843 0.0176041 0.0171122
Trypanosoma cruzi cytochrome P450, putative 0.00278484 0.00179267 0.00129288
Loa Loa (eye worm) hypothetical protein 0.00429707 0.00666877 0.00617143
Trypanosoma cruzi cysteine peptidase, putative 0.182258 0.580494 0.580284
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.00706599 0.015597 0.0248481
Echinococcus granulosus adam 17 protease 0.0118836 0.0311312 0.0306461
Brugia malayi Tubulin beta-1 chain 0.0237345 0.0693438 0.0692925
Echinococcus multilocularis AMPK beta subunit 0.00324397 0.00327312 0.00277407
Schistosoma mansoni amine GPCR 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.00293736 0.00228446 0.00178492
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0297584 0.0887674 0.0883112
Loa Loa (eye worm) hypothetical protein 0.00511295 0.00929954 0.00880351
Onchocerca volvulus 0.0339089 0.10215 0.175285
Schistosoma mansoni gliotactin 0.0114839 0.0298423 0.0297887
Echinococcus multilocularis BC026374 protein (S09 family) 0.0114839 0.0298423 0.0293565
Echinococcus multilocularis mitogen activated protein kinase 14 0.0124779 0.0330476 0.0325635
Echinococcus granulosus c-Jun N-terminal kinases 0.0108261 0.0277213 0.0272345
Loa Loa (eye worm) CMGC/GSK protein kinase 0.00745194 0.0168415 0.0163493
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0101101 0.0254124 0.0429522
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Brugia malayi cyclin-dependent kinase 9 0.00404895 0.00586872 0.00581386
Trichomonas vaginalis glucosylceramidase, putative 0.00973024 0.0241877 0.0408407
Echinococcus multilocularis Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.00287163 0.00207251 0.00157287
Trichomonas vaginalis tubulin, putative 0.0237345 0.0693438 0.118697
Plasmodium vivax aspartyl proteinase, putative 0.00950888 0.023474 0.03961
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00583583 0.0116304 0.0115759
Loa Loa (eye worm) hypothetical protein 0.188368 0.600196 0.599995
Schistosoma mansoni serine/threonine protein kinase 0.00758997 0.0172866 0.0172323
Echinococcus multilocularis cathepsin b 0.312359 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.153556 0.487948 0.840436
Brugia malayi Papain family cysteine protease containing protein 0.099263 0.312881 0.312844
Brugia malayi Carboxylesterase family protein 0.0679658 0.211965 0.211922
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0383289 0.116403 0.11596
Echinococcus multilocularis beta tubulin 0.0237345 0.0693438 0.0688779
Brugia malayi hypothetical protein 0.0114839 0.0298423 0.0297887
Loa Loa (eye worm) NEK/NEK6 protein kinase 0.0142865 0.0388794 0.0383982
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0339089 0.10215 0.175972
Echinococcus multilocularis ras gtpase 0.00459662 0.00763466 0.0071378
Brugia malayi SWIB/MDM2 domain containing protein 0.00618448 0.0127546 0.0127002
Schistosoma mansoni serine/threonine kinase 0.00551764 0.0106045 0.0105499
Echinococcus multilocularis tyrosine protein kinase Src42A 0.00409535 0.00601835 0.00552068
Loa Loa (eye worm) hypothetical protein 0.00280603 0.001861 0.00136125
Brugia malayi Matrixin family protein 0.00768843 0.0176041 0.0175499
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.00583583 0.0116304 0.0111356
Brugia malayi Serotonin receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Schistosoma mansoni tyrosine kinase 0.0306766 0.0917282 0.091678
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.00632282 0.0132007 0.33812
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0350178 0.105726 0.105279
Brugia malayi Papain family cysteine protease containing protein 0.0426756 0.130418 0.13037
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis protein kinase c epsilon type 0.00684915 0.0148978 0.0144046
Brugia malayi Protein kinase domain containing protein 0.0118228 0.030935 0.0308815
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.00430629 0.00669849 0.0106864
Onchocerca volvulus 0.0350178 0.105726 0.18145
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.00368632 0.00469944 0.00420111
Entamoeba histolytica hypothetical protein 0.0062898 0.0130942 0.022557
Echinococcus multilocularis nAChR subunit 0.00269638 0.00150744 0.00100751
Echinococcus granulosus tm gpcr rhodopsin 0.267042 0.853876 0.853803
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0350178 0.105726 0.18145
Schistosoma mansoni serine/threonine protein kinase 0.0315703 0.0946098 0.0945599
Echinococcus multilocularis rho associated protein kinase 0.0115219 0.029965 0.0294793
Loa Loa (eye worm) hypothetical protein 0.0383289 0.116403 0.11596
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.00462485 0.0077257 0.00722888
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) hypothetical protein 0.00429707 0.00666877 0.00617143
Brugia malayi Cation transporter family protein 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus hyperpolarization activated cyclic 0.00583583 0.0116304 0.0111356
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.00506665 0.00915025 0.00865415
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057134 0.0112357 0.0107406
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0297584 0.0887674 0.0887172
Loa Loa (eye worm) hypothetical protein 0.12567 0.398031 0.397729
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057134 0.0112357 0.0107406
Trichomonas vaginalis conserved hypothetical protein 0.0339089 0.10215 0.175261
Schistosoma mansoni integrin beta subunit 0.018997 0.054068 0.0540158
Loa Loa (eye worm) pigment dispersing factor receptor c 0.00279123 0.00181326 0.00131349
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Schistosoma mansoni hypothetical protein 0.0350178 0.105726 0.105677
Onchocerca volvulus 0.00618448 0.0127546 0.0211567
Echinococcus granulosus tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.00822065 0.0193202 0.0188292
Mycobacterium ulcerans proteasome PrcB 0.00569812 0.0111864 0.334898
Echinococcus multilocularis cyclin dependent kinase 1 0.00706599 0.015597 0.0151042
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Echinococcus multilocularis tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Echinococcus granulosus serine:threonine protein kinase 0.00511295 0.00929954 0.00880351
Trypanosoma cruzi cruzipain precursor, putative 0.190805 0.608055 0.607859
Loa Loa (eye worm) hypothetical protein 0.312359 1 1
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0106516 0.0271588 0.0266717
Entamoeba histolytica protein kinase, putative 0.00328095 0.00339235 0.00584391
Echinococcus granulosus proteasome prosome macropain 0.00569812 0.0111864 0.0106913
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.00551764 0.0106045 0.0101091
Brugia malayi serine/threonine-protein kinase plk-2 0.0855307 0.268603 0.268562
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Onchocerca volvulus 0.0297584 0.0887674 0.152211
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0164023 0.0457014 0.0452236
Schistosoma mansoni tyrosine kinase 0.00474767 0.00812172 0.00806699
Loa Loa (eye worm) matrix metalloproteinase 0.00768843 0.0176041 0.0171122
Giardia lamblia Cathepsin L-like protease 0.0426756 0.130418 0.266528
Echinococcus granulosus integrin beta 2 0.0238023 0.0695623 0.0690965
Onchocerca volvulus 0.0114839 0.0298423 0.0506176
Trichomonas vaginalis AGC family protein kinase 0.00388268 0.0053326 0.00833141
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00583583 0.0116304 0.0191899
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0350178 0.105726 0.105279
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.00388268 0.0053326 0.00483458
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0030568 0.0026696 0.00357031
Entamoeba histolytica cysteine proteinase, putative 0.099263 0.312881 0.538992
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0114839 0.0298423 0.0293565
Trichomonas vaginalis cyclins, putative 0.0491228 0.151207 0.259842
Echinococcus multilocularis cathepsin L 0.099263 0.312881 0.312537
Loa Loa (eye worm) serotonin transporter b 0.04587 0.140718 0.140288
Echinococcus granulosus glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Plasmodium falciparum transporter, putative 0.0297584 0.0887674 0.152186
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0491228 0.151207 0.248054
Trypanosoma cruzi regulatory subunit of protein kinase a-like protein, putative 0.00368632 0.00469944 0.00420111
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.00309933 0.00280674 0.00230746
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.00618448 0.0127546 0.0211282
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.00269638 0.00150744 0.00100751
Onchocerca volvulus 0.0350178 0.105726 0.18145
Entamoeba histolytica cysteine proteinase, putative 0.099263 0.312881 0.538992
Loa Loa (eye worm) hypothetical protein 0.00452414 0.00740096 0.00690398
Echinococcus granulosus mitogen activated protein kinase 14 0.0124779 0.0330476 0.0325635
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.00368632 0.00469944 0.00420111
Echinococcus granulosus sodium and chloride dependent glycine 0.138316 0.438808 0.438527
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Trichomonas vaginalis CMGC family protein kinase 0.0057134 0.0112357 0.0185092
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.00745194 0.0168415 0.0163493
Entamoeba histolytica PH domain containing protein kinase, putative 0.00638181 0.0133909 0.0230682
Echinococcus multilocularis mitogen activated protein kinase 14 0.0124779 0.0330476 0.0325635
Echinococcus granulosus Dipeptidyl peptidase 9 0.00811809 0.0189894 0.0184983
Trichomonas vaginalis cyclin D, putative 0.0229919 0.0669495 0.114569
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Entamoeba histolytica protein kinase, putative 0.00301562 0.00253681 0.0043701
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0339089 0.10215 0.101701
Onchocerca volvulus Glucosylceramidase homolog 0.00771694 0.017696 0.0296761
Echinococcus multilocularis para nitrobenzyl esterase 0.0114839 0.0298423 0.0293565
Echinococcus granulosus g protein coupled receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.00719882 0.0160253 0.0155327
Brugia malayi brahma associated protein 60 kDa 0.00618448 0.0127546 0.0127002
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0105036 0.0266814 0.0451679
Onchocerca volvulus Cathepsin L homolog 0.182258 0.580494 1
Brugia malayi casein kinase I 0.00238408 0.000500434 0.000445284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Schistosoma mansoni growth factor receptor-bound protein 0.00280603 0.001861 0.00180593
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0350178 0.105726 0.105677
Giardia lamblia Kinase, CMGC GSK 0.00745194 0.0168415 0.0335238
Trypanosoma cruzi cAMP binding protein, putative 0.00371334 0.00478657 0.00428828
Schistosoma mansoni hypothetical protein 0.0062898 0.0130942 0.0130398
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Leishmania major developmentally regulated phosphoprotein-like protein 0.00593037 0.0119353 0.0188211
Echinococcus multilocularis c src tyrosine kinase 0.00474767 0.00812172 0.0076251
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus granulosus raf serine:threonine protein kinase 0.00324612 0.00328006 0.00278101
Giardia lamblia Beta tubulin 0.0237345 0.0693438 0.141233
Brugia malayi excitatory GABA receptor EXP-1A 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) CAMK/PKD protein kinase 0.00675925 0.0146079 0.0141146
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.00616602 0.0126951 0.0210256
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Schistosoma mansoni protein kinase subunit beta 0.00324397 0.00327312 0.00321812
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0855307 0.268603 0.441281
Echinococcus granulosus nervana 2 0.00500833 0.0089622 0.00846601
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.138316 0.438808 0.438527
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0350178 0.105726 0.105677
Toxoplasma gondii AGC kinase 0.0030568 0.0026696 0.00373998
Schistosoma mansoni protein kinase 0.00402932 0.00580544 0.00575058
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0112626 0.0291288 0.974563
Loa Loa (eye worm) hypothetical protein 0.0379341 0.11513 0.114686
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.00328095 0.00339235 0.00289337
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0350178 0.105726 0.105279
Schistosoma mansoni serine/threonine protein kinase 0.0057134 0.0112357 0.0111811
Brugia malayi SH2 domain containing protein 0.00358585 0.00437548 0.00432054
Echinococcus multilocularis ephrin type A receptor 4 A 0.00461762 0.00770239 0.00720556
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Toxoplasma gondii cAMP-dependent protein kinase regulatory subunit 0.00368632 0.00469944 0.00723974
Trypanosoma cruzi cdc2-related kinase 1 0.00706599 0.015597 0.0151042
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0297584 0.0887674 0.0883112
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.00745194 0.0168415 0.0163493
Plasmodium falciparum protein kinase, putative 0.00309933 0.00280674 0.00397643
Entamoeba histolytica cysteine proteinase, putative 0.182258 0.580494 1
Plasmodium falciparum plasmepsin I 0.0383289 0.116403 0.199834
Echinococcus multilocularis acetylcholinesterase 0.0679658 0.211965 0.211571
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.0416292 0.127044 0.126607
Chlamydia trachomatis DNA topoisomerase I 0.00618448 0.0127546 0.0958178
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.00569812 0.0111864 0.0106913
Onchocerca volvulus 0.0297584 0.0887674 0.152211
Echinococcus granulosus protein kinase c epsilon type 0.00684915 0.0148978 0.0144046
Giardia lamblia Cysteine protease 0.0426756 0.130418 0.266528
Echinococcus granulosus beta tubulin 0.0237345 0.0693438 0.0688779
Loa Loa (eye worm) CAMK/PKD protein kinase 0.00545476 0.0104017 0.00990622
Loa Loa (eye worm) cyclin domain-containing protein 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.0221037 0.0640852 0.0636166
Echinococcus multilocularis G protein coupled receptor 139 0.0350178 0.105726 0.105279
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Schistosoma mansoni hypothetical protein 0.0350178 0.105726 0.105677
Echinococcus multilocularis glycine receptor subunit beta 0.00269638 0.00150744 0.00100751
Plasmodium vivax unspecified product 0.0565873 0.175276 0.301341
Trypanosoma cruzi cAMP response protein 1, putative 0.00368632 0.00469944 0.00420111
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni serine/threonine protein kinase 0.00706599 0.015597 0.0155427
Schistosoma mansoni integrin alpha-ps 0.00612794 0.0125723 0.0125178
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0108361 0.0277536 0.0272668
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Echinococcus granulosus alpha 1A adrenergic receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.138316 0.438808 0.438527
Plasmodium vivax glycogen synthase kinase 3, putative 0.00745194 0.0168415 0.0281746
Echinococcus multilocularis voltage gated potassium channel 0.00850189 0.020227 0.0197364
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.00506665 0.00915025 0.00865415
Trichomonas vaginalis cyclins, putative 0.0324206 0.0973518 0.166987
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.182258 0.580494 1
Brugia malayi Papain family cysteine protease containing protein 0.099263 0.312881 0.312844
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.00569812 0.0111864 0.258005
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062898 0.0130942 0.0130398
Schistosoma mansoni 60S ribosomal protein L21 0.00481557 0.00834066 0.00828594
Brugia malayi serine/threonine-protein kinase PAK 7 0.0134094 0.0360512 0.035998
Brugia malayi Protein kinase domain containing protein 0.00358585 0.00437548 0.00432054
Loa Loa (eye worm) hypothetical protein 0.00396329 0.00559253 0.00509465
Entamoeba histolytica cyclin C, putative 0.0062898 0.0130942 0.022557
Echinococcus granulosus mitogen activated protein kinase 11 0.0124779 0.0330476 0.0325635
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.152186
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0133443 0.0358412 0.035788
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.00950888 0.023474 0.03961
Schistosoma mansoni protein kinase 0.00938104 0.0230618 0.0230079
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.00768843 0.0176041 0.0175499
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Schistosoma mansoni integrin alpha 0.00612794 0.0125723 0.0125178
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426756 0.130418 0.223999
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.00404489 0.00585564 0.0100873
Echinococcus granulosus beta tubulin 0.0237345 0.0693438 0.0688779
Leishmania major hypothetical protein, conserved 0.00324397 0.00327312 0.00456367
Echinococcus granulosus Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Echinococcus granulosus cAMP dependent protein kinase type II regulatory 0.00368632 0.00469944 0.00420111
Schistosoma mansoni cathepsin B (C01 family) 0.0426756 0.130418 0.13037
Loa Loa (eye worm) hypothetical protein 0.00630888 0.0131557 0.0126616
Schistosoma mansoni cathepsin F (C01 family) 0.182258 0.580494 0.580471
Onchocerca volvulus 0.00950888 0.023474 0.039638
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Echinococcus multilocularis hypothetical protein 0.0031077 0.00283372 0.00233446
Toxoplasma gondii cathepsin CPC1 0.0426756 0.130418 0.223999
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.00608225 0.012425 0.0119305
Echinococcus multilocularis cysteine protease 0.182258 0.580494 0.580284
Trypanosoma brucei beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus granulosus tyrosine protein kinase HCK 0.00439278 0.00697741 0.00648022
Schistosoma mansoni neuropeptide receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.0120774 0.0317559 0.0312711
Giardia lamblia Kinase, CMGC CDK 0.00706599 0.015597 0.0309707
Trypanosoma cruzi cysteine peptidase, putative 0.0565873 0.175276 0.174863
Brugia malayi Carboxylesterase family protein 0.0114839 0.0298423 0.0297887
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0426756 0.130418 0.129983
Loa Loa (eye worm) hypothetical protein 0.0107729 0.0275497 0.0270628
Giardia lamblia Cathepsin B precursor 0.0426756 0.130418 0.266528
Toxoplasma gondii cathepsin CPC2 0.0426756 0.130418 0.223999
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0426756 0.130418 0.13037
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.00593037 0.0119353 0.0114406
Brugia malayi Fibronectin type III domain containing protein 0.00462485 0.0077257 0.00767095
Echinococcus multilocularis tyrosine kinase 0.00358585 0.00437548 0.00387698
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.00269638 0.00150744 0.00100751
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Trichomonas vaginalis tubulin epsilon chain, putative 0.0237345 0.0693438 0.118697
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.00618448 0.0127546 0.0211282
Trypanosoma brucei polo-like protein kinase 0.0855307 0.268603 0.441281
Entamoeba histolytica cyclin, domain containing protein 0.0062898 0.0130942 0.022557
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.00745194 0.0168415 0.0281746
Trypanosoma cruzi cyclin, putative 0.0491228 0.151207 0.150782
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.00404489 0.00585564 0.0100873
Schistosoma mansoni nck2/grb4 0.00280603 0.001861 0.00180593
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.00279187 0.00181533 0.00131555
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0426756 0.130418 0.223999
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Schistosoma mansoni protein kinase 0.00402932 0.00580544 0.00575058
Loa Loa (eye worm) hypothetical protein 0.0416292 0.127044 0.126607
Brugia malayi 5'-AMP-activated protein kinase, beta subunit, complex-interacting region containing protein 0.00324397 0.00327312 0.00321812
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.04587 0.140718 0.140671
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.00368632 0.00469944 0.00723974
Giardia lamblia Cathepsin B precursor 0.0426756 0.130418 0.266528
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426756 0.130418 0.13037
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) cytochrome P450 family protein 0.00278484 0.00179267 0.00129288
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.0223194 0.064781 0.0643127
Entamoeba histolytica cyclin, putative 0.0491228 0.151207 0.26048
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0117673 0.0307561 0.0302709
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis conserved hypothetical protein 0.0426756 0.130418 0.223999
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057134 0.0112357 0.0176696
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0426756 0.130418 0.223999
Echinococcus granulosus neuropeptides capa receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0124779 0.0330476 0.0325635
Brugia malayi cathepsin F-like cysteine proteinase 0.0565873 0.175276 0.175231
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0426756 0.130418 0.223999
Plasmodium falciparum NIMA related kinase 1 0.00689943 0.0150599 0.0251029
Brugia malayi beta-tubulin, identical 0.0237345 0.0693438 0.0692925
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.153556 0.487948 0.487691
Onchocerca volvulus Cyclin L homolog 0.0062898 0.0130942 0.0217422
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0426756 0.130418 0.223999
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Schistosoma mansoni hypothetical protein 0.0350178 0.105726 0.105677
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Schistosoma mansoni adenoreceptor 0.0350178 0.105726 0.105677
Trypanosoma brucei beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0073472 0.0165038 0.0160113
Echinococcus granulosus neuropeptide receptor A26 0.0386352 0.11739 0.116948
Echinococcus multilocularis calcium activated potassium channel 0.00641491 0.0134976 0.0130037
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.00811809 0.0189894 0.0184983
Echinococcus multilocularis cyclin B 0.0491228 0.151207 0.150782
Trichomonas vaginalis CMGC family protein kinase 0.00480698 0.00831297 0.01347
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.00280603 0.001861 0.00180593
Giardia lamblia Kinase, NEK 0.00689943 0.0150599 0.0298689
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0237345 0.0693438 0.0688779
Schistosoma mansoni vav2 0.00316448 0.0030168 0.00296179
Trypanosoma cruzi serine carboxypeptidase S28, putative 0.0339089 0.10215 0.101701
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Brugia malayi cAMP-dependent protein kinase regulatory chain, putative 0.00368632 0.00469944 0.00464452
Loa Loa (eye worm) hypothetical protein 0.00783841 0.0180877 0.017596
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Onchocerca volvulus 0.00368632 0.00469944 0.00726867
Loa Loa (eye worm) hypothetical protein 0.00583583 0.0116304 0.0111356
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Echinococcus multilocularis G-protein coupled receptor, putative 0.0350178 0.105726 0.105279
Echinococcus granulosus para nitrobenzyl esterase 0.0114839 0.0298423 0.0293565
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0855307 0.268603 0.268236
Brugia malayi hypothetical protein 0.00462485 0.0077257 0.00767095
Toxoplasma gondii cyclin domain protein, cyclin H family protein 0.0062898 0.0130942 0.0217137
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Schistosoma mansoni cell polarity protein 0.00459662 0.00763466 0.00757991
Echinococcus multilocularis cathepsin l cysteine peptidase 0.182258 0.580494 0.580284
Entamoeba histolytica cysteine protease, putative 0.182258 0.580494 1
Plasmodium vivax vivapain-3 0.099263 0.312881 0.538594
Plasmodium falciparum plasmepsin VIII, putative 0.00950888 0.023474 0.03961
Loa Loa (eye worm) G-protein coupled receptor 0.0350178 0.105726 0.105279
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Schistosoma mansoni adapter molecule crk 0.00280603 0.001861 0.00180593
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0210869 0.0608067 0.0603364
Onchocerca volvulus 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.026092 0.0769454 0.0764833
Brugia malayi Furin-like cysteine rich region family protein 0.0522689 0.161351 0.161305
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0427026 0.130506 0.130458
Brugia malayi SRC-1 0.00719882 0.0160253 0.015971
Brugia malayi hypothetical protein 0.00480528 0.00830747 0.00825276
Echinococcus multilocularis g protein coupled receptor 0.0350178 0.105726 0.105279
Plasmodium falciparum plasmepsin X 0.00950888 0.023474 0.03961
Giardia lamblia CAMP-dependent protein kinase regulatory chain 0.00368632 0.00469944 0.00861427
Trichomonas vaginalis cyclin A, putative 0.0491228 0.151207 0.259842
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Brugia malayi Protein kinase domain containing protein 0.0210869 0.0608067 0.0607549
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0350178 0.105726 0.105279
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Trichomonas vaginalis AGC family protein kinase 0.00605368 0.0123329 0.020401
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0315703 0.0946098 0.0941565
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0297584 0.0887674 0.0883112
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.12567 0.398031 0.685405
Plasmodium falciparum serine repeat antigen 3 0.0426756 0.130418 0.223999
Schistosoma mansoni serine/threonine protein kinase 0.00903343 0.0219409 0.021887
Echinococcus multilocularis cyclin dependent kinase 1 0.00706599 0.015597 0.0151042
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Plasmodium falciparum serine repeat antigen 1 0.0426756 0.130418 0.223999
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Echinococcus multilocularis serine:threonine protein kinase 0.00511295 0.00929954 0.00880351
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Onchocerca volvulus 0.0107729 0.0275497 0.0466649
Loa Loa (eye worm) hypothetical protein 0.0565873 0.175276 0.174863
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) fibroinase 0.182258 0.580494 0.580284
Leishmania major protein kinase A regulatory subunit, putative 0.00368632 0.00469944 0.00691131
Trichomonas vaginalis tubulin beta chain, putative 0.0237345 0.0693438 0.118697
Leishmania major cysteine peptidase A (CPA) 0.182258 0.580494 0.954635
Mycobacterium ulcerans hypothetical protein 0.00368632 0.00469944 0.10363
Schistosoma mansoni hypothetical protein 0.0350178 0.105726 0.105677
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0333527 0.100357 0.0999067
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.00811809 0.0189894 0.0304318
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0426756 0.130418 0.223999
Brugia malayi C1-like domain containing protein 0.00675925 0.0146079 0.0145536
Trichomonas vaginalis cyclin B, putative 0.0229919 0.0669495 0.114569
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Toxoplasma gondii aspartyl protease ASP1 0.0383289 0.116403 0.199834
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Echinococcus granulosus tubulin beta 1 chain 0.0237345 0.0693438 0.0688779
Brugia malayi Serine carboxypeptidase S28 family protein 0.188368 0.600196 0.600174
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) carboxylesterase 0.0679658 0.211965 0.211571
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.00506665 0.00915025 0.0142371
Brugia malayi Protein kinase domain containing protein 0.00506665 0.00915025 0.00909558
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Brugia malayi hypothetical protein 0.0297584 0.0887674 0.0887172
Trypanosoma brucei cdc2-related kinase 3 0.00706599 0.015597 0.0248481
Giardia lamblia Beta tubulin 0.0237345 0.0693438 0.141233
Giardia lamblia Beta tubulin 0.0237345 0.0693438 0.141233
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Plasmodium vivax CAMP-dependent protein kinase regulatory subunit, putative 0.00368632 0.00469944 0.00723974
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.00246218 0.000752262 0.000251955
Onchocerca volvulus 0.0426756 0.130418 0.224022
Trichomonas vaginalis conserved hypothetical protein 0.00618448 0.0127546 0.0211282
Trichomonas vaginalis cyclin B, putative 0.0491228 0.151207 0.259842
Echinococcus granulosus c src tyrosine kinase 0.00474767 0.00812172 0.0076251
Giardia lamblia Cathepsin B precursor 0.153556 0.487948 1
Echinococcus multilocularis cyclin G2 0.0062898 0.0130942 0.0126001
Trypanosoma brucei rac serine-threonine kinase, putative 0.0107418 0.0274494 0.0443563
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.00368632 0.00469944 0.00723974
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) TK/INSR protein kinase 0.033252 0.100032 0.0995818
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0383289 0.116403 0.199834
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.00304314 0.00262556 0.00212619
Brugia malayi Kelch motif family protein 0.00480528 0.00830747 0.00825276
Trichomonas vaginalis CMGC family protein kinase 0.00706599 0.015597 0.0260289
Onchocerca volvulus Putative nachr subunit 0.00269638 0.00150744 0.00176532
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0315703 0.0946098 0.0941565
Brugia malayi hypothetical protein 0.0062898 0.0130942 0.0130398
Schistosoma mansoni tyrosine kinase 0.0306766 0.0917282 0.091678
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0260058 0.0766673 0.076205
Giardia lamblia Kinase, NEK 0.00689943 0.0150599 0.0298689
Leishmania major cathepsin L-like protease 0.182258 0.580494 0.954635
Trypanosoma cruzi cdc2-related kinase 3 0.00706599 0.015597 0.0151042
Trypanosoma cruzi cyclin 6, putative 0.0491228 0.151207 0.150782
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0105036 0.0266814 0.026194
Echinococcus multilocularis serine:threonine protein kinase 0.00511295 0.00929954 0.00880351
Giardia lamblia Kinase, CDC7 0.00480698 0.00831297 0.0160275
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0354179 0.107016 0.106569
Schistosoma mansoni pyruvate dehydrogenase 0.00593037 0.0119353 0.0118807
Echinococcus multilocularis cAMP dependent protein kinase regulatory 0.00368632 0.00469944 0.00420111
Echinococcus multilocularis serotonin transporter 0.04587 0.140718 0.140288
Loa Loa (eye worm) hypothetical protein 0.0107729 0.0275497 0.0270628
Onchocerca volvulus 0.182258 0.580494 1
Entamoeba histolytica protein kinase 2, putative 0.00616602 0.0126951 0.0218695
Echinococcus multilocularis myosin iiia 0.00404489 0.00585564 0.00535788
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0357744 0.108166 0.107719
Loa Loa (eye worm) hypothetical protein 0.00997685 0.0249829 0.0244948
Echinococcus granulosus cathepsin l1 0.182258 0.580494 0.580284
Schistosoma mansoni cathepsin S (C01 family) 0.0426756 0.130418 0.13037
Loa Loa (eye worm) hypothetical protein 0.00630888 0.0131557 0.0126616
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Giardia lamblia Cathepsin B precursor 0.153556 0.487948 1
Loa Loa (eye worm) neuropeptide F receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Trichomonas vaginalis CMGC family protein kinase 0.00745194 0.0168415 0.0281746
Onchocerca volvulus 0.00429707 0.00666877 0.010664
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.00404489 0.00585564 0.00535788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) matrixin family protein 0.0170525 0.0477982 0.0473214
Echinococcus granulosus G protein coupled receptor 139 0.0350178 0.105726 0.105279
Echinococcus granulosus dual specificity testis-specific protein kinase 0.00938104 0.0230618 0.0225726
Schistosoma mansoni serine/threonine protein kinase 0.00246218 0.000752262 0.000697126
Brugia malayi Hemopexin family protein 0.00903945 0.0219603 0.0219064
Onchocerca volvulus 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Schistosoma mansoni Cyclin fold protein 0.0062898 0.0130942 0.0130398
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Plasmodium vivax aspartyl protease, putative 0.00950888 0.023474 0.03961
Echinococcus multilocularis cyclin b3 0.0229919 0.0669495 0.0664823
Onchocerca volvulus 0.00560155 0.010875 0.017916
Echinococcus multilocularis fmrfamide receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cyclins 0.0229919 0.0669495 0.0664823
Plasmodium falciparum amino acid transporter, putative 0.0297584 0.0887674 0.152186
Schistosoma mansoni neuroligin 3 (S09 family) 0.0114839 0.0298423 0.0297887
Entamoeba histolytica protein kinase domain containing protein 0.00404895 0.00586872 0.0101099
Echinococcus multilocularis integrin alpha 3 0.00293736 0.00228446 0.00178492
Trypanosoma brucei 5'-AMP-activated protein kinase subunit beta 0.00324397 0.00327312 0.00456367
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Onchocerca volvulus 0.0297584 0.0887674 0.152211
Brugia malayi GTP-binding protein, identical 0.00459662 0.00763466 0.00757991
Brugia malayi putative neuropeptide receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni cyclin d 0.0062898 0.0130942 0.0130398
Onchocerca volvulus 0.0114839 0.0298423 0.0506176
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.00402932 0.00580544 0.00530766
Brugia malayi Matrixin family protein 0.00768843 0.0176041 0.0175499
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.00618448 0.0127546 0.0211282
Loa Loa (eye worm) cysteine protease 0.182258 0.580494 0.580284
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Brugia malayi cyclin-dependent kinase 7 homolog 0.00661829 0.0141534 0.014099
Schistosoma mansoni biogenic amine receptor 0.0350178 0.105726 0.105677
Onchocerca volvulus Matrilysin homolog 0.00768843 0.0176041 0.0295176
Echinococcus multilocularis hyperpolarization activated cyclic 0.00583583 0.0116304 0.0111356
Loa Loa (eye worm) hypothetical protein 0.00319058 0.00310096 0.00260183
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Schistosoma mansoni serine/threonine protein kinase 0.0030568 0.0026696 0.00261457
Trichomonas vaginalis cyclin B3, putative 0.0062898 0.0130942 0.0217137
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Schistosoma mansoni serine/threonine protein kinase 0.00328095 0.00339235 0.00333736
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Echinococcus granulosus serine:threonine protein kinase N2 0.00551764 0.0106045 0.0101091
Mycobacterium leprae Conserved hypothetical protein 0.00368632 0.00469944 0.118683
Brugia malayi MAP kinase sur-1 0.0057134 0.0112357 0.0111811
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus multilocularis cathepsin l cysteine peptidase 0.182258 0.580494 0.580284
Trypanosoma cruzi Protein kinase B 0.00638181 0.0133909 0.0128969
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Echinococcus multilocularis serine:threonine protein kinase N2 0.00551764 0.0106045 0.0101091
Brugia malayi putative neuropeptide receptor NPR1 0.0350178 0.105726 0.105677
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.00811809 0.0189894 0.0189353
Plasmodium falciparum cGMP-dependent protein kinase 0.00484401 0.00843236 0.0136759
Loa Loa (eye worm) carboxylesterase 0.0114839 0.0298423 0.0293565
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.00279123 0.00181326 0.00175818
Entamoeba histolytica protein kinase, putative 0.00279984 0.00184102 0.00317147
Brugia malayi Hypothetical UPF0028 protein ZK370.4 in chromosome III, putative 0.00368632 0.00469944 0.00464452
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Loa Loa (eye worm) tubulin beta-4 chain 0.0237345 0.0693438 0.0688779
Entamoeba histolytica protein kinase domain containing protein 0.00745194 0.0168415 0.0290124
Schistosoma mansoni serine/threonine protein kinase 0.00238718 0.000510436 0.000455287
Schistosoma mansoni cyclin B 0.0491228 0.151207 0.15116
Brugia malayi SH2 domain containing protein 0.00358585 0.00437548 0.00432054
Toxoplasma gondii protein kinase G AGC kinase family member PKG 0.00484401 0.00843236 0.0136759
Loa Loa (eye worm) hypothetical protein 0.12567 0.398031 0.397729
Giardia lamblia Kinase, CMGC MAPK 0.0057134 0.0112357 0.0220234
Echinococcus granulosus cGMP dependent protein kinase 1 0.00484401 0.00843236 0.0079359
Toxoplasma gondii aurora kinase 0.0101101 0.0254124 0.0429522
Trypanosoma cruzi protein kinase A regulatory subunit 0.00368632 0.00469944 0.00420111
Leishmania major protein kinase A catalytic subunit isoform 1 0.0030568 0.0026696 0.00357031
Plasmodium vivax plasmepsin V, putative 0.00950888 0.023474 0.03961
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.00500833 0.0089622 0.00846601
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) melatonin receptor type 1A 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) CYL-1 protein 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.00706599 0.015597 0.0151042
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trypanosoma brucei mitotic cyclin 0.0062898 0.0130942 0.0207286
Entamoeba histolytica protein kinase, putative 0.00551764 0.0106045 0.018268
Schistosoma mansoni sodium-dependent amino acid transporter 0.0297584 0.0887674 0.0887172
Trypanosoma brucei proteasome subunit beta type-5, putative 0.00569812 0.0111864 0.0175885
Echinococcus granulosus cyclin 0.0106516 0.0271588 0.0266717
Trichomonas vaginalis cyclin B, putative 0.0062898 0.0130942 0.0217137
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) hypothetical protein 0.00390896 0.00541733 0.00491936
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062898 0.0130942 0.0130398
Trypanosoma cruzi cysteine peptidase, putative 0.190805 0.608055 0.607859
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.00246218 0.000752262 0.000251955
Schistosoma mansoni cyclin l 0.0062898 0.0130942 0.0130398
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Brugia malayi Pepsin A precursor 0.00950888 0.023474 0.0234201
Schistosoma mansoni neuropeptide F-like receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426756 0.130418 0.13037
Loa Loa (eye worm) hypothetical protein 0.00545865 0.0104142 0.00991877
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0030568 0.0026696 0.00217025
Trypanosoma cruzi aurora B kinase, putative 0.0101101 0.0254124 0.0249245
Trypanosoma cruzi cysteine peptidase, putative 0.099263 0.312881 0.312537
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.00569812 0.0111864 0.0106913
Schistosoma mansoni tyrosine kinase 0.033252 0.100032 0.0999827
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.0883112
Onchocerca volvulus 0.0350178 0.105726 0.18145
Brugia malayi Cyclin, N-terminal domain containing protein 0.0491228 0.151207 0.15116
Echinococcus granulosus protein kinase c iota type 0.00682213 0.0148107 0.0143174
Onchocerca volvulus 0.0114839 0.0298423 0.0506176
Trichomonas vaginalis conserved hypothetical protein 0.0339089 0.10215 0.175261
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0087495 0.0210254 0.0205353
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.00404489 0.00585564 0.00535788
Onchocerca volvulus Protein CNPPD1 homolog 0.0062898 0.0130942 0.0217422
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0350178 0.105726 0.105677
Echinococcus granulosus cyclin dependent kinase 0.00706599 0.015597 0.0151042
Brugia malayi cell division control protein 2 homolog 0.00706599 0.015597 0.0155427
Echinococcus granulosus g protein coupled receptor 0.0350178 0.105726 0.105279
Trypanosoma cruzi cdc2-related kinase 3 0.00706599 0.015597 0.0151042
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trypanosoma brucei cyclin 9 0.0062898 0.0130942 0.0207286
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.00269638 0.00150744 0.00145234
Onchocerca volvulus 0.00745194 0.0168415 0.0282029
Echinococcus granulosus acetylcholinesterase 0.0679658 0.211965 0.211571
Echinococcus granulosus tyrosine protein kinase shark 0.00358585 0.00437548 0.00387698
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0416292 0.127044 0.126996
Brugia malayi Protein kinase domain containing protein 0.00758997 0.0172866 0.0172323
Toxoplasma gondii cyclin dependent kinase binding protein 0.0062898 0.0130942 0.0217137
Echinococcus multilocularis serotonin receptor 0.0379341 0.11513 0.114686
Onchocerca volvulus 0.0115219 0.029965 0.0508292
Loa Loa (eye worm) ctsf protein 0.182258 0.580494 0.580284
Echinococcus multilocularis raf serine:threonine protein kinase 0.00324612 0.00328006 0.00278101
Entamoeba histolytica cyclin family protein 0.0229919 0.0669495 0.115332
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Loa Loa (eye worm) sex muscle abnormal protein 5 0.00280603 0.001861 0.00136125
Toxoplasma gondii aspartyl protease 0.00950888 0.023474 0.03961
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus granulosus sodium and chloride dependent glycine 0.138316 0.438808 0.438527
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0383289 0.116403 0.199834
Brugia malayi Papain family cysteine protease containing protein 0.0426756 0.130418 0.13037
Schistosoma mansoni brg-1 associated factor 0.00618448 0.0127546 0.0127002
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) hypothetical protein 0.00390896 0.00541733 0.00491936
Loa Loa (eye worm) TK protein kinase 0.00439278 0.00697741 0.00648022
Onchocerca volvulus Cathepsin L homolog 0.0426756 0.130418 0.224022
Entamoeba histolytica cysteine proteinase, putative 0.182258 0.580494 1
Echinococcus granulosus adam 0.00363952 0.00454854 0.00405014
Schistosoma mansoni acetylcholinesterase 0.0114839 0.0298423 0.0297887
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426756 0.130418 0.223999
Plasmodium vivax unspecified product 0.099263 0.312881 0.538594
Echinococcus multilocularis neuropeptides capa receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Echinococcus multilocularis proteasome (prosome, macropain) 0.00569812 0.0111864 0.0106913
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.00488926 0.00857828 0.0132957
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0350178 0.105726 0.105279
Entamoeba histolytica cyclin, domain containing protein 0.0062898 0.0130942 0.022557
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.00616602 0.0126951 0.0210256
Trichomonas vaginalis hypothetical protein 0.00266606 0.00140966 0.00156765
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0350178 0.105726 0.105677
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.00745194 0.0168415 0.0268964
Brugia malayi aspartic protease BmAsp-2, identical 0.00950888 0.023474 0.0234201
Echinococcus granulosus AMPK beta subunit 0.00324397 0.00327312 0.00277407
Echinococcus granulosus cathepsin b 0.312359 1 1
Schistosoma mansoni serine/threonine-protein kinase 0.00638181 0.0133909 0.0133365
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0339089 0.10215 0.175261
Schistosoma mansoni protein kinase 0.00938104 0.0230618 0.0230079
Onchocerca volvulus 0.0491228 0.151207 0.259863
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Trypanosoma cruzi cruzipain precursor, putative 0.0565873 0.175276 0.174863
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.00511295 0.00929954 0.00880351
Onchocerca volvulus 0.0114839 0.0298423 0.0506176
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0855307 0.268603 0.268236
Echinococcus multilocularis nervana 2 0.00500833 0.0089622 0.00846601
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Echinococcus multilocularis rac serine:threonine kinase 0.00638181 0.0133909 0.0128969
Schistosoma mansoni serine/threonine protein kinase 0.0210869 0.0608067 0.0607549
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Trypanosoma cruzi cyclin, putative 0.0491228 0.151207 0.150782
Echinococcus multilocularis cyclin y 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis cyclin B, putative 0.0491228 0.151207 0.259842
Echinococcus granulosus activin receptor type 0.00309933 0.00280674 0.00230746
Brugia malayi aspartic protease BmAsp-1, identical 0.00950888 0.023474 0.0234201
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.00388268 0.0053326 0.00483458
Schistosoma mansoni lysosomal Pro-Xaa carboxypeptidase (S28 family) 0.188368 0.600196 0.600174
Trichomonas vaginalis adenylate cyclase type III, putative 0.00266606 0.00140966 0.00156765
Leishmania major mitotic cyclin, putative 0.0062898 0.0130942 0.0207286
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0459497 0.140976 0.140545
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Plasmodium vivax hypothetical protein, conserved 0.00618448 0.0127546 0.0211282
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426756 0.130418 0.13037
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Loa Loa (eye worm) hypothetical protein 0.00452911 0.00741697 0.00692
Echinococcus granulosus defective proboscis extension response 0.00452414 0.00740096 0.00690398
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Leishmania major protein kinase, putative 0.00484401 0.00843236 0.0130555
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.00294869 0.002321 0.00226595
Plasmodium falciparum serine/threonine protein kinase, putative 0.0101101 0.0254124 0.0429522
Plasmodium falciparum plasmepsin V 0.00950888 0.023474 0.03961
Echinococcus granulosus serine:threonine protein kinase 0.00511295 0.00929954 0.00880351
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.00719882 0.0160253 0.0155327
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.00294869 0.002321 0.00182148
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0164023 0.0457014 0.0452236
Echinococcus granulosus aurora kinase A 0.0101101 0.0254124 0.0249245
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Giardia lamblia Kinase, STE STE20 0.00404489 0.00585564 0.0109862
Echinococcus multilocularis cysteine protease 0.182258 0.580494 0.580284
Brugia malayi hypothetical protein 0.00950888 0.023474 0.0234201
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.00725625 0.0162105 0.0157179
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.00506665 0.00915025 0.00865415
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.00551764 0.0106045 0.0101091
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Echinococcus granulosus Protein kinase C brain isozyme 0.0087495 0.0210254 0.0205353
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cGMP dependent protein kinase 1 0.00484401 0.00843236 0.0079359
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Trichomonas vaginalis CMGC family protein kinase 0.00480698 0.00831297 0.01347
Trichomonas vaginalis cyclin B3, putative 0.0062898 0.0130942 0.0217137
Brugia malayi Variant SH3 domain containing protein 0.00280603 0.001861 0.00180593
Schistosoma mansoni serine/threonine protein kinase 0.00246218 0.000752262 0.000697126
Brugia malayi Cation transporter family protein 0.00269638 0.00150744 0.00145234
Plasmodium falciparum serine repeat antigen 8 0.0426756 0.130418 0.223999
Schistosoma mansoni sodium/chloride dependent transporter 0.04587 0.140718 0.140671
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0297584 0.0887674 0.0887172
Loa Loa (eye worm) hypothetical protein 0.00319058 0.00310096 0.00260183
Entamoeba histolytica cyclin, putative 0.0229919 0.0669495 0.115332
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.00368632 0.00469944 0.00420111
Brugia malayi serine/threonine protein kinase 6 0.0101101 0.0254124 0.0253587
Schistosoma mansoni serine/threonine protein kinase 0.0047456 0.00811506 0.00806033
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Giardia lamblia Thymus-specific serine protease precursor 0.0339089 0.10215 0.208536
Schistosoma mansoni serine/threonine protein kinase 0.00484401 0.00843236 0.00837765
Brugia malayi RhoGAP domain containing protein 0.00294869 0.002321 0.00226595
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis adenylyl cyclase type V, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cyclin G2 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.12567 0.398031 0.397729
Brugia malayi Serine/threonine-protein kinase Pim-3 0.00758997 0.0172866 0.0172323
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0260058 0.0766673 0.0766164
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Trypanosoma brucei aurora B kinase 0.0101101 0.0254124 0.0410037
Schistosoma mansoni tyrosine kinase 0.00474767 0.00812172 0.00806699
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.00500833 0.0089622 0.00846601
Brugia malayi hypothetical protein 0.00358585 0.00437548 0.00432054
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cyclins 0.0229919 0.0669495 0.0664823
Loa Loa (eye worm) CAMK/PIM protein kinase 0.00758997 0.0172866 0.0167945
Loa Loa (eye worm) prolyl oligopeptidase 0.0105036 0.0266814 0.026194
Loa Loa (eye worm) tubulin beta chain 0.0237345 0.0693438 0.0688779
Echinococcus multilocularis serine:threonine protein kinase 3 0.0123321 0.0325773 0.0320929
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) AUR protein kinase 0.0101101 0.0254124 0.0249245
Echinococcus multilocularis integrin beta 2 0.0238023 0.0695623 0.0690965
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.0887172
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni neuropeptide receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.00568972 0.0111593 0.0111048
Brugia malayi p70 ribosomal S6 kinase beta 0.010526 0.0267536 0.0266999
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Loa Loa (eye worm) cytochrome P450 family protein 0.00278484 0.00179267 0.00129288
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.00583583 0.0116304 0.0111356
Echinococcus multilocularis neuroglian 0.00537437 0.0101425 0.00964686
Leishmania major cathepsin L-like protease 0.182258 0.580494 0.954635
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0124779 0.0330476 0.0535707
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0030568 0.0026696 0.00373998
Trichomonas vaginalis STE family protein kinase 0.00402932 0.00580544 0.00914666
Trichomonas vaginalis cyclin B, putative 0.0062898 0.0130942 0.0217137
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0565873 0.175276 0.175231
Loa Loa (eye worm) hypothetical protein 0.0261308 0.0770706 0.0766085
Echinococcus granulosus NDR protein kinase 0.00551764 0.0106045 0.0101091
Schistosoma mansoni biogenic amine (5HT) receptor 0.0475169 0.146029 0.145982
Echinococcus granulosus tyrosine protein kinase Fps85D 0.00358585 0.00437548 0.00387698
Schistosoma mansoni tyrosine kinase 0.00916122 0.022353 0.022299
Schistosoma mansoni voltage-gated potassium channel 0.00583583 0.0116304 0.0115759
Schistosoma mansoni tyrosine kinase 0.0522689 0.161351 0.161305
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0426756 0.130418 0.223999
Schistosoma mansoni serine/threonine protein kinase 0.00684915 0.0148978 0.0148435
Brugia malayi cathepsin F-like cysteine proteinase 0.0426756 0.130418 0.13037
Loa Loa (eye worm) hypothetical protein 0.0030568 0.0026696 0.00217025
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0426756 0.130418 0.223999
Echinococcus multilocularis cyclin dependent kinase 5 0.00706599 0.015597 0.0151042
Loa Loa (eye worm) TK/EGFR protein kinase 0.0522689 0.161351 0.160931
Brugia malayi Serotonin receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.00758997 0.0172866 0.0167945
Chlamydia trachomatis SWIB complex protein 0.00618448 0.0127546 0.0958178
Echinococcus granulosus glycine receptor subunit beta 0.00269638 0.00150744 0.00100751
Brugia malayi Protein kinase domain containing protein 0.00246218 0.000752262 0.000697126
Echinococcus multilocularis Cyclin L1 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis conserved hypothetical protein 0.0229919 0.0669495 0.114569
Echinococcus multilocularis basement membrane specific heparan sulfate 0.00452414 0.00740096 0.00690398
Echinococcus multilocularis neuropeptide receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Trypanosoma cruzi polo-like protein kinase, putative 0.0855307 0.268603 0.268236
Brugia malayi brahma associated protein 60 kDa 0.00618448 0.0127546 0.0127002
Brugia malayi G protein-coupled receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.00903343 0.0219409 0.0214512
Echinococcus multilocularis sodium and chloride dependent glycine 0.138316 0.438808 0.438527
Echinococcus multilocularis cathepsin L 0.0426756 0.130418 0.129983
Plasmodium falciparum plasmepsin IV 0.0383289 0.116403 0.199834
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0112626 0.0291288 0.971622
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00583583 0.0116304 0.0191899
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.04587 0.140718 0.140288
Brugia malayi Protein kinase domain containing protein 0.00358585 0.00437548 0.00432054
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Echinococcus granulosus tyrosine protein kinase Src42A 0.00719882 0.0160253 0.0155327
Brugia malayi ORL1-like opioid receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni serine/threonine protein kinase 0.00426539 0.00656665 0.00651183
Schistosoma mansoni growth hormone secretagogue receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.00269638 0.00150744 0.00100751
Echinococcus multilocularis acetylcholinesterase 0.0679658 0.211965 0.211571
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0124779 0.0330476 0.0535707
Entamoeba histolytica cysteine proteinase, putative 0.099263 0.312881 0.538992
Schistosoma mansoni similar to Protein C20orf152 homolog 0.00368632 0.00469944 0.00464452
Echinococcus granulosus tyrosine kinase 0.00603699 0.0122791 0.0117845
Loa Loa (eye worm) beta-tubulin 0.0237345 0.0693438 0.0688779
Entamoeba histolytica SH2-protein kinase domain containing protein 0.00358585 0.00437548 0.00753751
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426756 0.130418 0.223999
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Trypanosoma cruzi rac serine-threonine kinase, putative 0.00616602 0.0126951 0.0122008
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0062898 0.0130942 0.0126001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Trichomonas vaginalis CAMK family protein kinase 0.0855307 0.268603 0.46225
Echinococcus granulosus cyclin y 0.0062898 0.0130942 0.0126001
Plasmodium vivax cyclin 4, putative 0.0062898 0.0130942 0.0217137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.00569812 0.0111864 0.0192705
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0030568 0.0026696 0.00217025
Brugia malayi Protein kinase domain containing protein 0.00706599 0.015597 0.0155427
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057134 0.0112357 0.0176696
Trichomonas vaginalis mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative 0.00238718 0.000510436 0.0000172453
Loa Loa (eye worm) hypothetical protein 0.00560155 0.010875 0.0103798
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0350178 0.105726 0.105279
Echinococcus multilocularis epidermal growth factor receptor 0.0326182 0.0979889 0.0975372
Trypanosoma brucei STE group serine/threonine-protein kinase, putative 0.00382375 0.00514258 0.0076407
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Onchocerca volvulus 0.0350178 0.105726 0.18145
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426756 0.130418 0.13037
Trichomonas vaginalis cyclin H, putative 0.0040655 0.00592209 0.00934779
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.153556 0.487948 0.802309
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.00618448 0.0127546 0.0211282
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Echinococcus multilocularis tyrosine protein kinase Abl 0.0118633 0.0310656 0.0305804
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0101101 0.0254124 0.0437773
Loa Loa (eye worm) CMGC/GSK protein kinase 0.00745194 0.0168415 0.0163493
Schistosoma mansoni protein kinase C mu 0.00675925 0.0146079 0.0145536
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426756 0.130418 0.266528
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.00269638 0.00150744 0.00100751
Toxoplasma gondii preprocathepsin c precursor, putative 0.0426756 0.130418 0.223999
Echinococcus granulosus cysteine protease 0.099263 0.312881 0.312537
Schistosoma mansoni pyruvate dehydrogenase 0.00561136 0.0109066 0.0108521
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Echinococcus granulosus tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Brugia malayi G-protein coupled receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni biogenic amine receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.00320484 0.00314693 0.00264782
Brugia malayi neuropeptide F receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Trypanosoma brucei mitotic cyclin 6 0.0491228 0.151207 0.248054
Schistosoma mansoni camp-dependent protein kinase type II-alpha regulatory subunit 0.00368632 0.00469944 0.00464452
Loa Loa (eye worm) AGC/NDR protein kinase 0.00551764 0.0106045 0.0101091
Brugia malayi Protein kinase domain 0.00402932 0.00580544 0.00575058
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0073472 0.0165038 0.0160113
Brugia malayi Cyclin, N-terminal domain containing protein 0.0212608 0.0613675 0.0613157
Loa Loa (eye worm) SRC-1 0.00719882 0.0160253 0.0155327
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0297584 0.0887674 0.0883112
Trichomonas vaginalis conserved hypothetical protein 0.0426756 0.130418 0.223999
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0062898 0.0130942 0.0126001
Echinococcus multilocularis neuropeptide s receptor 0.0386352 0.11739 0.116948
Giardia lamblia Kinase, AGC AKT 0.00467348 0.00788248 0.0151443
Onchocerca volvulus 0.0350178 0.105726 0.18145
Trichomonas vaginalis adenylate cyclase type IX, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus cyclin B3 1 0.0229919 0.0669495 0.0664823
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.00269638 0.00150744 0.00100751
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Schistosoma mansoni tyrosine kinase 0.0306766 0.0917282 0.091678
Echinococcus multilocularis tyrosine protein kinase Fyn 0.00603699 0.0122791 0.0117845
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0350178 0.105726 0.105279
Plasmodium vivax aspartyl protease, putative 0.00950888 0.023474 0.03961
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus granulosus tubulin subunit beta 0.0237345 0.0693438 0.0688779
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis N chimaerin 0.00294869 0.002321 0.00182148
Trypanosoma cruzi cysteine proteinase, putative 0.099263 0.312881 0.312537
Echinococcus granulosus serine/threonine protein kinase 0.00638181 0.0133909 0.0128969
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Trichomonas vaginalis STE family protein kinase 0.00404489 0.00585564 0.00923321
Schistosoma mansoni hypothetical protein 0.00903945 0.0219603 0.0219064
Echinococcus multilocularis cAMP dependent protein kinase type I beta 0.00368632 0.00469944 0.00420111
Plasmodium falciparum cyclin dependent kinase binding protein, putative 0.0062898 0.0130942 0.0217137
Loa Loa (eye worm) hypothetical protein 0.0297584 0.0887674 0.0883112
Echinococcus granulosus glycogen synthase kinase 3 beta 0.00745194 0.0168415 0.0163493
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Onchocerca volvulus 0.182258 0.580494 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0164023 0.0457014 0.0456487
Plasmodium falciparum plasmepsin II 0.0383289 0.116403 0.199834
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Mycobacterium ulcerans transmembrane transport protein 0.00368632 0.00469944 0.10363
Brugia malayi ribosomal protein S6 kinase alpha 3 0.00467348 0.00788248 0.00782774
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.00327957 0.00338792 0.00288893
Giardia lamblia Kinase, STE STE20 0.00402932 0.00580544 0.0108832
Schistosoma mansoni neuropeptide receptor 0.0350178 0.105726 0.105677
Onchocerca volvulus 0.00480698 0.00831297 0.0134988
Echinococcus granulosus cyclic nucleotide gated cation channel 0.00583583 0.0116304 0.0111356
Schistosoma mansoni serine/threonine kinase 0.00480143 0.00829508 0.00824036
Echinococcus granulosus cyclin dependent kinase 9 0.00404895 0.00586872 0.00537097
Schistosoma mansoni sodium/chloride dependent transporter 0.139474 0.442541 0.44251
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Leishmania major cathepsin L-like protease 0.182258 0.580494 0.954635
Schistosoma mansoni neuropeptide receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni serine/threonine protein kinase 0.0087495 0.0210254 0.0209714
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.00551764 0.0106045 0.0101091
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Brugia malayi cathepsin B-like cysteine proteinase 0.312359 1 1
Loa Loa (eye worm) cyclin domain-containing protein 0.0229919 0.0669495 0.0664823
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Plasmodium falciparum cyclin 1 0.0062898 0.0130942 0.0217137
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.00758997 0.0172866 0.0167945
Echinococcus granulosus tyrosine protein kinase Src42A 0.00409535 0.00601835 0.00552068
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Loa Loa (eye worm) dihydrofolate reductase 0.0112626 0.0291288 0.0286427
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.099263 0.312881 0.514161
Schistosoma mansoni neuropeptide f receptor 76f 0.0350178 0.105726 0.105677
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Echinococcus granulosus g-protein coupled receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis cathepsin L cysteine protease 0.182258 0.580494 0.580284
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0117673 0.0307561 0.0302709
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0101101 0.0254124 0.0249245
Schistosoma mansoni g1/s-specific cyclin C 0.0106516 0.0271588 0.0271051
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.00269638 0.00150744 0.00100751
Schistosoma mansoni opsin-like receptor 0.0350178 0.105726 0.105677
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0030568 0.0026696 0.00357031
Brugia malayi neuropeptide F receptor 0.0350178 0.105726 0.105677
Echinococcus multilocularis PAK box P21 Rho binding 0.00279984 0.00184102 0.00134126
Giardia lamblia Cysteine protease 0.0426756 0.130418 0.266528
Schistosoma mansoni hypothetical protein 0.00618448 0.0127546 0.0127002
Loa Loa (eye worm) solute carrier family 6 member 4 0.04587 0.140718 0.140288
Onchocerca volvulus 0.0350178 0.105726 0.18145
Plasmodium vivax vivapain-2 0.182258 0.580494 1
Onchocerca volvulus 0.0350178 0.105726 0.18145
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.00676128 0.0146145 0.0145601
Loa Loa (eye worm) cyclin domain-containing protein 0.0212608 0.0613675 0.0608976
Trypanosoma brucei cytochrome P450, putative 0.00278484 0.00179267 0.00212694
Brugia malayi fibroinase precursor 0.0426756 0.130418 0.13037
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.00452414 0.00740096 0.00734619
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis adam 17 protease 0.0105956 0.0269782 0.026491
Loa Loa (eye worm) acetylcholinesterase 1 0.0679658 0.211965 0.211571
Schistosoma mansoni thyroid hormone receptor 0.00464976 0.00780602 0.00775128
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.00616602 0.0126951 0.0122008
Onchocerca volvulus 0.0350178 0.105726 0.18145
Leishmania major cathepsin L-like protease 0.190805 0.608055 1
Schistosoma mansoni BC026374 protein (S09 family) 0.0114839 0.0298423 0.0297887
Schistosoma mansoni tyrosine kinase 0.00372638 0.00482861 0.0047737
Echinococcus granulosus neuropeptide Y receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.0491228 0.151207 0.150782
Echinococcus granulosus hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Plasmodium falciparum serine repeat antigen 4 0.0426756 0.130418 0.223999
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Echinococcus granulosus cathepsin L 0.0426756 0.130418 0.129983
Leishmania major protein kinase A catalytic subunit 0.0030568 0.0026696 0.00357031
Echinococcus granulosus neuroglian 0.00537437 0.0101425 0.00964686
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0426756 0.130418 0.223999
Brugia malayi hypothetical protein 0.00396329 0.00559253 0.00553766
Brugia malayi Tachykinin-like peptides receptor 99D 0.0350178 0.105726 0.105677
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.00294869 0.002321 0.00226595
Brugia malayi Integrin alpha pat-2 precursor 0.00612794 0.0125723 0.0125178
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0426756 0.130418 0.223999
Echinococcus granulosus rho-associated protein kinase 1 0.0115219 0.029965 0.0294793
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Echinococcus granulosus Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Trichomonas vaginalis conserved hypothetical protein 0.0062898 0.0130942 0.0217137
Loa Loa (eye worm) TYRA-2 protein 0.0350178 0.105726 0.105279
Echinococcus granulosus g protein coupled receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.0679658 0.211965 0.211571
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.00569812 0.0111864 0.0106913
Echinococcus multilocularis Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus multilocularis cyclin 0.0106516 0.0271588 0.0266717
Loa Loa (eye worm) AGC/PKA protein kinase 0.0030568 0.0026696 0.00217025
Brugia malayi Cathepsin L-like precursor 0.0565873 0.175276 0.175231
Echinococcus multilocularis serine threonine protein kinase 0.00744502 0.0168192 0.0163269
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.152186
Echinococcus granulosus serine:threonine protein kinase MARK2 0.00822065 0.0193202 0.0188292
Trichomonas vaginalis CMGC family protein kinase 0.0057134 0.0112357 0.0185092
Trypanosoma brucei beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.00402932 0.00580544 0.00530766
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0297584 0.0887674 1
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.00402932 0.00580544 0.00530766
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis cyclins, putative 0.0491228 0.151207 0.259842
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Echinococcus multilocularis protein kinase shaggy 0.00745194 0.0168415 0.0163493
Brugia malayi Serine protease Z688.6 precursor 0.0339089 0.10215 0.102101
Echinococcus granulosus serotonin receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis STE family protein kinase 0.00279984 0.00184102 0.00231138
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.00402932 0.00580544 0.00530766
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.00583583 0.0116304 0.0111356
Onchocerca volvulus 0.00768843 0.0176041 0.0295176
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00583583 0.0116304 0.0115759
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Entamoeba histolytica protein kinase, putative 0.00402932 0.00580544 0.0100009
Echinococcus granulosus cyclin dependent kinase 5 0.00706599 0.015597 0.0151042
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.182258 0.580494 0.580284
Echinococcus granulosus tyrosine kinase 0.00358585 0.00437548 0.00387698
Trypanosoma cruzi cysteine peptidase, putative 0.190805 0.608055 0.607859
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus granulosus fibroblast growth factor receptor 4 0.0108361 0.0277536 0.0272668
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0101101 0.0254124 0.0249245
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.00441872 0.00706103 0.00656388
Echinococcus granulosus G1:S specific cyclin D1 0.0062898 0.0130942 0.0126001
Leishmania major proteasome beta 5 subunit, putative 0.00569812 0.0111864 0.0175885
Echinococcus multilocularis growth factor receptor bound protein 2 0.00280603 0.001861 0.00136125
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.00545865 0.0104142 0.00991877
Schistosoma mansoni cyclin G2 0.0062898 0.0130942 0.0130398
Echinococcus multilocularis cGMP dependent protein kinase 1 0.00484401 0.00843236 0.0079359
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Schistosoma mansoni cyclic nucleotide-gated ion channel 0.00368632 0.00469944 0.00464452
Brugia malayi hypothetical protein 0.0062898 0.0130942 0.0130398
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0124779 0.0330476 0.0325635
Loa Loa (eye worm) GTP-binding protein 0.00459662 0.00763466 0.0071378
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Loa Loa (eye worm) CYP4Cod1 0.00278484 0.00179267 0.00129288
Trichomonas vaginalis cAMP-dependent protein kinase type I-beta regulatory subunit, putative 0.00368632 0.00469944 0.00723974
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426756 0.130418 0.223999
Trichomonas vaginalis AGC family protein kinase 0.00573343 0.0113002 0.0186206
Onchocerca volvulus Matrix metalloproteinase homolog 0.0170525 0.0477982 0.0815755
Loa Loa (eye worm) TK/ABL protein kinase 0.0221958 0.0643824 0.063914
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni opsin-like receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus neuroligin 0.0114839 0.0298423 0.0293565
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Echinococcus granulosus cyclin G2 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.00358585 0.00437548 0.00387698
Schistosoma mansoni amine GPCR 0.0350178 0.105726 0.105677
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0383289 0.116403 0.116354
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0426756 0.130418 0.129983
Echinococcus granulosus neuropeptide receptor 0.0350178 0.105726 0.105279
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.00372914 0.00483753 0.00433927
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0383289 0.116403 0.11596
Brugia malayi Kinase associated domain 1 family protein 0.0031077 0.00283372 0.0027787
Entamoeba histolytica casein kinase 1, putative 0.00238408 0.000500434 0.000862083
Brugia malayi Protein kinase c protein 2 0.00438955 0.00696698 0.00691219
Giardia lamblia Kinase, AGC PKA 0.0030568 0.0026696 0.00445005
Trichomonas vaginalis CAMK family protein kinase 0.0860668 0.270331 0.46523
Brugia malayi Protein kinase domain containing protein 0.00358585 0.00437548 0.00432054
Loa Loa (eye worm) hypothetical protein 0.00293736 0.00228446 0.00178492
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.00402932 0.00580544 0.00530766
Trichomonas vaginalis prolylcarboxypeptidase, putative 0.0339089 0.10215 0.175261
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.00309933 0.00280674 0.00379604
Schistosoma mansoni serine/threonine-protein kinase 0.00638181 0.0133909 0.0133365
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus multilocularis neuropeptides capa receptor 0.0350178 0.105726 0.105279
Schistosoma mansoni ste20-related kinase 0.0094449 0.0232677 0.0232138
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0030568 0.0026696 0.00373998
Echinococcus multilocularis sodium and chloride dependent glycine 0.138316 0.438808 0.438527
Echinococcus granulosus integrin alpha 3 0.00293736 0.00228446 0.00178492
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.00238718 0.000510436 0.0000100072
Onchocerca volvulus 0.0350178 0.105726 0.18145
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00368632 0.00469944 0.00464452
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.312359 1 1
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062898 0.0130942 0.0130398
Loa Loa (eye worm) hypothetical protein 0.00783841 0.0180877 0.017596
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Entamoeba histolytica protein kinase, putative 0.0101101 0.0254124 0.0437773
Echinococcus multilocularis CDC7 cell division cycle 7 0.00480698 0.00831297 0.00781645
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.00689943 0.0150599 0.0251029
Schistosoma mansoni kinase 0.00404895 0.00586872 0.00581386
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.00474767 0.00812172 0.00806699
Schistosoma mansoni cathepsin F (C01 family) 0.182258 0.580494 0.580471
Echinococcus multilocularis Immunoglobulin 0.00452414 0.00740096 0.00690398
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.00616602 0.0126951 0.0122008
Mycobacterium ulcerans transcriptional regulatory protein 0.00368632 0.00469944 0.10363
Loa Loa (eye worm) hypothetical protein 0.0162905 0.045341 0.044863
Trypanosoma cruzi p21-activated kinase 3, putative 0.00238718 0.000510436 0.0000100072
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.00269638 0.00150744 0.00100751
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0426756 0.130418 0.13037
Loa Loa (eye worm) cyclin domain-containing protein 0.0062898 0.0130942 0.0126001
Echinococcus multilocularis tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Schistosoma mansoni ephrin receptor 0.00461762 0.00770239 0.00764764
Loa Loa (eye worm) LGC-31 protein 0.00269638 0.00150744 0.00100751
Brugia malayi Cathepsin L-like cysteine proteinase 0.12567 0.398031 0.397998
Echinococcus granulosus cyclin dependent kinase 1 0.00706599 0.015597 0.0151042
Schistosoma mansoni tyrosine kinase 0.00358378 0.00436881 0.00431388
Plasmodium falciparum glycogen synthase kinase 3 0.00745194 0.0168415 0.0281746
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Loa Loa (eye worm) papain family cysteine protease containing protein 0.182258 0.580494 0.580284
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Echinococcus granulosus calcium activated potassium channel 0.00641491 0.0134976 0.0130037
Echinococcus multilocularis insulin receptor 0.033252 0.100032 0.0995818
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062898 0.0130942 0.0130398
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.00850189 0.020227 0.0197364
Plasmodium vivax cyclin homologue, putative 0.0062898 0.0130942 0.0217137
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Echinococcus granulosus cyclin k 0.0062898 0.0130942 0.0126001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.00811809 0.0189894 0.0184983
Onchocerca volvulus 0.0350178 0.105726 0.18145
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Plasmodium vivax vivapain-2 0.182258 0.580494 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.099263 0.312881 0.538594
Giardia lamblia Hypothetical protein 0.0426756 0.130418 0.266528
Leishmania major cytochrome p450-like protein 0.00278484 0.00179267 0.00212694
Echinococcus multilocularis nervana 2 0.00500833 0.0089622 0.00846601
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Brugia malayi Matrixin family protein 0.0167279 0.0467513 0.0466987
Schistosoma mansoni serine/threonine protein kinase 0.00551764 0.0106045 0.0105499
Echinococcus granulosus cathepsin L cysteine protease 0.099263 0.312881 0.312537
Loa Loa (eye worm) hypothetical protein 0.00503224 0.00903931 0.00854315
Schistosoma mansoni sodium/chloride dependent transporter 0.138316 0.438808 0.438777
Plasmodium falciparum cysteine proteinase falcipain 2b 0.182258 0.580494 1
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.00269638 0.00150744 0.00145234
Plasmodium falciparum plasmepsin VII 0.00950888 0.023474 0.03961
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0114839 0.0298423 1
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0426756 0.130418 0.223999
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0105036 0.0266814 0.026194
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Trichomonas vaginalis cyclins, putative 0.0062898 0.0130942 0.0217137
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0297584 0.0887674 0.0883112
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0426756 0.130418 0.223999
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057134 0.0112357 0.0176696
Loa Loa (eye worm) ACC-1 protein 0.00269638 0.00150744 0.00100751
Brugia malayi Cyclic-nucleotide gated cation channel 0.00583583 0.0116304 0.0115759
Onchocerca volvulus Cyclin L homolog 0.0062898 0.0130942 0.0217422
Schistosoma mansoni atypical protein kinase C 0.00682213 0.0148107 0.0147563
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Brugia malayi protein kinase C3,putative 0.00246218 0.000752262 0.000697126
Brugia malayi Hr1 repeat family protein 0.00551764 0.0106045 0.0105499
Trichomonas vaginalis AGC family protein kinase 0.0030568 0.0026696 0.00373998
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.00358585 0.00437548 0.00387698
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.0456793 0.140104 0.139673
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0028019 0.00184768 0.00318295
Echinococcus multilocularis SWI:SNF matrix associated 0.00618448 0.0127546 0.0122604
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.0297584 0.0887674 0.0883112
Trichomonas vaginalis conserved hypothetical protein 0.0062898 0.0130942 0.0217137
Echinococcus granulosus neuropeptide Y receptor 0.0350178 0.105726 0.105279
Onchocerca volvulus Matrilysin homolog 0.0170525 0.0477982 0.0815755
Echinococcus granulosus neuropeptide s receptor 0.0386352 0.11739 0.116948
Echinococcus multilocularis roundabout 2 0.00640959 0.0134805 0.0129866
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0426756 0.130418 0.224668
Schistosoma mansoni serine/threonine protein kinase 0.0142865 0.0388794 0.0388263
Loa Loa (eye worm) TK protein kinase 0.0116864 0.0304951 0.0300097
Echinococcus granulosus Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Giardia lamblia Hypothetical protein 0.0062898 0.0130942 0.0258362
Schistosoma mansoni amine GPCR 0.0350178 0.105726 0.105677
Loa Loa (eye worm) brahma associated protein 0.00618448 0.0127546 0.0122604
Brugia malayi Matrixin family protein 0.00768843 0.0176041 0.0175499
Schistosoma mansoni serine/threonine protein kinase 0.00480698 0.00831297 0.00825825
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Trypanosoma cruzi cysteine peptidase, putative 0.190805 0.608055 0.607859
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.00462738 0.00773384 0.00723703
Echinococcus granulosus integrin alpha ps 0.00293736 0.00228446 0.00178492
Brugia malayi Papain family cysteine protease containing protein 0.182258 0.580494 0.580471
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0238562 0.0697363 0.119374
Entamoeba histolytica p21-activated kinase 0.00424511 0.00650123 0.0111995
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.12567 0.398031 0.685405
Loa Loa (eye worm) tubulin beta-2A chain 0.0237345 0.0693438 0.0688779
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.00309933 0.00280674 0.00397643
Echinococcus granulosus cyclin y 0.0062898 0.0130942 0.0126001
Entamoeba histolytica cysteine proteinase 1, putative 0.099263 0.312881 0.538992
Echinococcus granulosus NCK adaptor protein 0.00280603 0.001861 0.00136125
Toxoplasma gondii beta-tubulin, putative 0.0237345 0.0693438 0.118697
Brugia malayi Serine protease Z688.6 precursor 0.0339089 0.10215 0.102101
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Trichomonas vaginalis CMGC family protein kinase 0.00745194 0.0168415 0.0281746
Plasmodium falciparum protein kinase 5 0.00706599 0.015597 0.0260289
Entamoeba histolytica protein kinase domain containing protein 0.0101101 0.0254124 0.0437773
Schistosoma mansoni hypothetical protein 0.00293736 0.00228446 0.00222941
Echinococcus multilocularis fmrfamide receptor 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) RhoGAP domain-containing protein 0.00294869 0.002321 0.00182148
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Brugia malayi Cathepsin L-like precursor 0.12567 0.398031 0.397998
Schistosoma mansoni hypothetical protein 0.0031077 0.00283372 0.0027787
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.188368 0.600196 0.599995
Echinococcus multilocularis integrin alpha ps 0.00293736 0.00228446 0.00178492
Toxoplasma gondii cathepsin CPL 0.182258 0.580494 1
Loa Loa (eye worm) carboxylesterase 0.0114839 0.0298423 0.0293565
Echinococcus multilocularis mitogen activated protein kinase 11 0.0124779 0.0330476 0.0325635
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00583583 0.0116304 0.0115759
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0679658 0.211965 0.211922
Echinococcus granulosus cyclins 0.0229919 0.0669495 0.0664823
Schistosoma mansoni Neurotrimin precursor (hNT) 0.00452414 0.00740096 0.00734619
Schistosoma mansoni amine GPCR 0.0350178 0.105726 0.105677
Onchocerca volvulus 0.182258 0.580494 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0350178 0.105726 0.105279
Brugia malayi N-terminal motif family protein 0.00368632 0.00469944 0.00464452
Echinococcus granulosus dual specificity 0.00506665 0.00915025 0.00865415
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.00368632 0.00469944 0.00464452
Echinococcus granulosus cathepsin l1 0.12567 0.398031 0.397729
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Plasmodium falciparum plasmepsin IX 0.00950888 0.023474 0.03961
Trichomonas vaginalis STE family protein kinase 0.00402932 0.00580544 0.00914666
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.00269638 0.00150744 0.00145234
Echinococcus granulosus growth factor receptor bound protein 2 0.00280603 0.001861 0.00136125
Onchocerca volvulus 0.0350178 0.105726 0.18145
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.00368632 0.00469944 0.00464452
Schistosoma mansoni serine/threonine protein kinase 0.00238718 0.000510436 0.000455287
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.00404489 0.00585564 0.00881435
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.00279187 0.00181533 0.00131555
Plasmodium falciparum plasmepsin VI 0.0383289 0.116403 0.199834
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0030568 0.0026696 0.00217025
Echinococcus multilocularis Glutaredoxin protein 5 0.00500833 0.0089622 0.00846601
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0426756 0.130418 0.224668
Loa Loa (eye worm) hypothetical protein 0.188368 0.600196 0.599995
Entamoeba histolytica protein kinase, putative 0.00506665 0.00915025 0.0157629
Echinococcus multilocularis cyclin y 0.0062898 0.0130942 0.0126001
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Echinococcus multilocularis cathepsin b 0.312359 1 1
Schistosoma mansoni hypothetical protein 0.00618448 0.0127546 0.0127002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.099263 0.312881 0.312844
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis neuroligin 0.0114839 0.0298423 0.0293565
Loa Loa (eye worm) BEN-1 protein 0.0237345 0.0693438 0.0688779
Echinococcus multilocularis dual specificity 0.00506665 0.00915025 0.00865415
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Loa Loa (eye worm) hypothetical protein 0.00768843 0.0176041 0.0171122
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426756 0.130418 0.266528
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Schistosoma mansoni myosin xvIII 0.0350178 0.105726 0.105677
Entamoeba histolytica protein kinase, putative 0.0107418 0.0274494 0.0472862
Chlamydia trachomatis dihydrofolate reductase 0.0112626 0.0291288 0.29059
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.00426539 0.00656665 0.00606925
Entamoeba histolytica protein kinase , putative 0.0101101 0.0254124 0.0437773
Entamoeba histolytica protein kinase domain containing protein 0.00745194 0.0168415 0.0290124
Echinococcus multilocularis activin receptor type 0.00309933 0.00280674 0.00230746
Plasmodium vivax tubulin beta chain, putative 0.0237345 0.0693438 0.118697
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.00452414 0.00740096 0.00690398
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.00725625 0.0162105 0.0157179
Schistosoma mansoni serine/threonine protein kinase 0.00822065 0.0193202 0.0192661
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.00269638 0.00150744 0.00100751
Brugia malayi RE15519p 0.0350178 0.105726 0.105677
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.00269638 0.00150744 0.00145234
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0350178 0.105726 0.105279
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0855307 0.268603 0.268236
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.00719882 0.0160253 0.0155327
Schistosoma mansoni hypothetical protein 0.00372914 0.00483753 0.00478262
Trichomonas vaginalis CAMK family protein kinase 0.00511295 0.00929954 0.0151711
Echinococcus granulosus tubulin beta 4A class IVa 0.0237345 0.0693438 0.0688779
Brugia malayi Egg laying defective protein 4 0.00484401 0.00843236 0.00837765
Loa Loa (eye worm) hypothetical protein 0.0059083 0.0118641 0.0113694
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.00593037 0.0119353 0.0114406
Loa Loa (eye worm) cytochrome P450 family protein 0.00311638 0.00286171 0.00236246
Loa Loa (eye worm) integrin beta-2 0.0290669 0.0865379 0.0860805
Schistosoma mansoni serine/threonine protein kinase 0.0108261 0.0277213 0.0276676
Echinococcus granulosus a disintegrin and metalloproteinase with 0.00462738 0.00773384 0.00723703
Giardia lamblia Encystation-specific protease 0.0426756 0.130418 0.266528
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis beta tubulin 0.0237345 0.0693438 0.0688779
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Brugia malayi Cyclin, N-terminal domain containing protein 0.0229919 0.0669495 0.066898
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.00368632 0.00469944 0.00464452
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Brugia malayi Variant SH3 domain containing protein 0.00280603 0.001861 0.00180593
Echinococcus granulosus tm gpcr rhodopsin 0.0631579 0.196462 0.19606
Brugia malayi Proteasome A-type and B-type family protein 0.00569812 0.0111864 0.0111319
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057134 0.0112357 0.0185092
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0350178 0.105726 0.105279
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.00811809 0.0189894 0.0304318
Onchocerca volvulus 0.0350178 0.105726 0.18145
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0426756 0.130418 0.13037
Echinococcus multilocularis g-protein coupled receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis neuropeptide Y receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.00269638 0.00150744 0.00100751
Echinococcus multilocularis mitogen activated protein kinase 11 0.0124779 0.0330476 0.0325635
Trichomonas vaginalis adenylate cyclase type, putative 0.00266606 0.00140966 0.00156765
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Plasmodium vivax aspartyl protease, putative 0.00950888 0.023474 0.03961
Loa Loa (eye worm) hypothetical protein 0.182258 0.580494 0.580284
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.00368632 0.00469944 0.00691131
Plasmodium falciparum serine repeat antigen 2 0.0426756 0.130418 0.223999
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057134 0.0112357 0.0107406
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.00675925 0.0146079 0.0145536
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.00758997 0.0172866 0.0289703
Schistosoma mansoni integrin alpha-4 0.0308423 0.0922625 0.0922124
Trypanosoma brucei developmentally regulated phosphoprotein 0.00593037 0.0119353 0.0188211
Trichomonas vaginalis AGC family protein kinase 0.0101101 0.0254124 0.0429522
Schistosoma mansoni camp-dependent protein kinase regulatory chain 0.00368632 0.00469944 0.00464452
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis G1:S specific cyclin D1 0.0062898 0.0130942 0.0126001
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.099263 0.312881 0.312844
Trypanosoma brucei cyclin 3 0.0062898 0.0130942 0.0207286
Loa Loa (eye worm) cyclin domain-containing protein 0.0147171 0.0402678 0.0397873
Echinococcus granulosus tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Onchocerca volvulus 0.00238408 0.000500434 0.0000291402
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0326182 0.0979889 0.0975372
Echinococcus granulosus biogenic amine 5HT receptor 0.0475169 0.146029 0.145601
Entamoeba histolytica hypothetical protein 0.00506665 0.00915025 0.0157629
Loa Loa (eye worm) CAMK/PIM protein kinase 0.00758997 0.0172866 0.0167945
Schistosoma mansoni serine/threonine protein kinase 0.00404895 0.00586872 0.00581386
Brugia malayi Cathepsin L-like precursor 0.182258 0.580494 0.580471
Echinococcus multilocularis tyrosine protein kinase HCK 0.00439278 0.00697741 0.00648022
Echinococcus granulosus cyclins 0.0229919 0.0669495 0.0664823
Entamoeba histolytica PH domain containing protein kinase, putative 0.00638181 0.0133909 0.0230682
Loa Loa (eye worm) hypothetical protein 0.00267598 0.00144167 0.000941709
Trypanosoma brucei protein kinase, putative 0.00309933 0.00280674 0.00379604
Plasmodium vivax hypothetical protein, conserved 0.0297584 0.0887674 0.152186
Trypanosoma cruzi mitotic cyclin, putative 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.0565873 0.175276 0.174863
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.00706599 0.015597 0.0151042
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Leishmania major cathepsin L-like protease 0.190805 0.608055 1
Onchocerca volvulus 0.0280176 0.0831545 0.142534
Echinococcus multilocularis tyrosine protein kinase Srms 0.00603699 0.0122791 0.0117845
Brugia malayi cathepsin Z-like cysteine proteinase 0.0426756 0.130418 0.13037
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00373998
Giardia lamblia Kinase, CMGC GSK 0.00745194 0.0168415 0.0335238
Leishmania major cathepsin L-like protease 0.182258 0.580494 0.954635
Echinococcus granulosus cyclin B 0.0491228 0.151207 0.150782
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.312359 1 1
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Echinococcus granulosus glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Echinococcus granulosus orexin receptor type 2 0.0350178 0.105726 0.105279
Toxoplasma gondii hypothetical protein 0.0062898 0.0130942 0.0217137
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Echinococcus multilocularis Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Giardia lamblia Cysteine protease 0.0426756 0.130418 0.266528
Loa Loa (eye worm) cyclin domain-containing protein 0.0062898 0.0130942 0.0126001
Echinococcus granulosus cyclins 0.0229919 0.0669495 0.0664823
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.00719882 0.0160253 0.0155327
Onchocerca volvulus Alicorn homolog 0.00281804 0.00189972 0.00244165
Onchocerca volvulus 0.04587 0.140718 0.24178
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Echinococcus granulosus serotonin transporter 0.04587 0.140718 0.140288
Echinococcus granulosus cyclin dependent kinase 9 0.00458499 0.00759715 0.00710027
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.00294869 0.002321 0.00182148
Echinococcus multilocularis tubulin beta 1 chain 0.0237345 0.0693438 0.0688779
Echinococcus granulosus tm gpcr rhodopsin 0.0350178 0.105726 0.105279
Trypanosoma cruzi cysteine protease, putative 0.099263 0.312881 0.312537
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.010323 0.0260992 0.0256116
Schistosoma mansoni protein kinase 0.00279984 0.00184102 0.00178594
Schistosoma mansoni serine/threonine protein kinase 0.00608225 0.012425 0.0123705
Trichomonas vaginalis cAMP-dependent protein kinase regulatory subunit, putative 0.00368632 0.00469944 0.00723974
Plasmodium falciparum cyclin 0.0229919 0.0669495 0.114569
Plasmodium vivax vivapain-1 0.099263 0.312881 0.538594
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus allatostatin A receptor 0.0350178 0.105726 0.105279
Onchocerca volvulus Tyrosine kinase homolog 0.0308095 0.0921567 0.158054
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0426756 0.130418 0.223999
Trypanosoma cruzi hypothetical protein, conserved 0.00368632 0.00469944 0.00420111
Schistosoma mansoni cyclin B3 0.0229919 0.0669495 0.066898
Giardia lamblia Kinase, NEK 0.00689943 0.0150599 0.0298689
Echinococcus granulosus serine threonine protein kinase nrc 0.00616602 0.0126951 0.0122008
Echinococcus multilocularis neuropeptide receptor A26 0.0386352 0.11739 0.116948
Schistosoma mansoni serine/threonine protein kinase 0.00426539 0.00656665 0.00651183
Toxoplasma gondii hypothetical protein 0.0297584 0.0887674 0.152186
Echinococcus granulosus biogenic amine 5HT receptor 0.0379341 0.11513 0.114686
Echinococcus granulosus dihydrofolate reductase 0.0112626 0.0291288 0.0286427
Entamoeba histolytica cysteine proteinase, putative 0.12567 0.398031 0.685676
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.00435995 0.00687153 0.0109848
Schistosoma mansoni cell adhesion molecule 0.00555936 0.010739 0.0106844
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trypanosoma cruzi cAMP response protein 1 0.00368632 0.00469944 0.00420111
Brugia malayi STE20-like kinase MST 0.0123321 0.0325773 0.0325239
Echinococcus granulosus cyclin A3 4 0.0062898 0.0130942 0.0126001
Echinococcus granulosus serine:threonine protein kinase Chk2 0.00328095 0.00339235 0.00289337
Toxoplasma gondii hypothetical protein 0.0297584 0.0887674 0.152186
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0339089 0.10215 0.175972
Trichomonas vaginalis tubulin alpha chain, putative 0.0237345 0.0693438 0.118697
Onchocerca volvulus 0.0350178 0.105726 0.18145
Schistosoma mansoni serine/threonine protein kinase 0.00238408 0.000500434 0.000445284
Trichomonas vaginalis adenylate cyclase type VI, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Eukaryotic aspartyl protease family protein 0.00950888 0.023474 0.0234201
Echinococcus multilocularis allatostatin A receptor 0.0350178 0.105726 0.105279
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.00822065 0.0193202 0.0188292
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Brugia malayi Protein kinase domain containing protein 0.00551764 0.0106045 0.0105499
Entamoeba histolytica protein kinase, putative 0.0028019 0.00184768 0.00318295
Echinococcus granulosus potassium voltage gated channel subfamily H 0.00850189 0.020227 0.0197364
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0101101 0.0254124 0.0437773
Toxoplasma gondii beta tubulin 0.0237345 0.0693438 0.118697
Schistosoma mansoni serine/threonine protein kinase 0.0115219 0.029965 0.0299115
Brugia malayi intracellular kinase 0.00745194 0.0168415 0.0167872
Giardia lamblia Kinase, PLK 0.0855307 0.268603 0.550013
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.134218 0.425593 0.425305
Brugia malayi protein kinase C II. 0.00684915 0.0148978 0.0148435
Loa Loa (eye worm) matrixin family protein 0.0167279 0.0467513 0.046274
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0426756 0.130418 0.223999
Mycobacterium ulcerans hypothetical protein 0.00368632 0.00469944 0.10363
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0350178 0.105726 0.105677
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0133443 0.0358412 0.0353585
Echinococcus granulosus cyclin dependent kinase 7 0.00608225 0.012425 0.0119305
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.00269638 0.00150744 0.00100751
Echinococcus granulosus tyrosine protein kinase Srms 0.00358585 0.00437548 0.00387698
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.312359 1 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0350178 0.105726 0.105279
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Schistosoma mansoni tyrosine kinase 0.00719882 0.0160253 0.015971
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0221958 0.0643824 0.063914
Trypanosoma cruzi cytochrome P450, putative 0.00278484 0.00179267 0.00129288
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0112626 0.0291288 1
Echinococcus multilocularis aurora kinase A 0.0101101 0.0254124 0.0249245
Trichomonas vaginalis glucosylceramidase, putative 0.00973024 0.0241877 0.0408407
Loa Loa (eye worm) TK protein kinase 0.00603699 0.0122791 0.0117845
Schistosoma mansoni voltage-gated potassium channel 0.00850189 0.020227 0.0201729
Schistosoma mansoni cathepsin D (A01 family) 0.116695 0.369091 0.369056
Trypanosoma cruzi rac serine-threonine kinase, putative 0.00638181 0.0133909 0.0128969
Brugia malayi cathepsin Z-like cysteine proteinase 0.0426756 0.130418 0.13037
Echinococcus multilocularis tyrosine protein kinase Blk 0.00603699 0.0122791 0.0117845
Giardia lamblia Cathepsin L-like protease 0.0426756 0.130418 0.266528
Entamoeba histolytica protein kinase, putative 0.0107418 0.0274494 0.0472862
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0030568 0.0026696 0.00217025
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Giardia lamblia Hypothetical protein 0.0426756 0.130418 0.266528
Onchocerca volvulus 0.00903945 0.0219603 0.0370283
Echinococcus granulosus cGMP dependent protein kinase 0.00484401 0.00843236 0.0079359
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.00269638 0.00150744 0.00100751
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.00368632 0.00469944 0.00420111
Toxoplasma gondii proteasome subunit beta type, putative 0.00569812 0.0111864 0.0184243
Schistosoma mansoni tyrosine kinase 0.033252 0.100032 0.0999827
Brugia malayi kinase, mitochondrial precursor 0.00593037 0.0119353 0.0118807
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00368632 0.00469944 0.00723974
Toxoplasma gondii AGC kinase 0.010526 0.0267536 0.0452645
Trypanosoma brucei protein kinase, putative 0.00745194 0.0168415 0.0268964
Leishmania major hypothetical protein, conserved 0.00368632 0.00469944 0.00691131
Loa Loa (eye worm) hypothetical protein 0.0297584 0.0887674 0.0883112
Brugia malayi Protein kinase domain containing protein 0.00426539 0.00656665 0.00651183
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00583583 0.0116304 0.0115759
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.00551764 0.0106045 0.0101091
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Cathepsin L-like precursor 0.12567 0.398031 0.397998
Echinococcus granulosus Cyclin L1 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) G-protein coupled receptor 0.0350178 0.105726 0.105279
Trypanosoma brucei cAMP response protein 1, putative 0.00368632 0.00469944 0.00691131
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0030568 0.0026696 0.00261457
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.099263 0.312881 0.312844
Loa Loa (eye worm) tubulin beta-1 chain 0.0237345 0.0693438 0.0688779
Brugia malayi sulfakinin receptor protein 0.0350178 0.105726 0.105677
Echinococcus granulosus twitchin 0.00653206 0.0138754 0.0133817
Giardia lamblia G2/mitotic-specific cyclin B 0.0491228 0.151207 0.309175
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Trypanosoma cruzi cdc2-related kinase 1 0.00706599 0.015597 0.0151042
Trypanosoma brucei cdc2-related kinase 1 0.00706599 0.015597 0.0248481
Trypanosoma cruzi mitotic cyclin, putative 0.0062898 0.0130942 0.0126001
Brugia malayi Integrin alpha cytoplasmic region family protein 0.00293736 0.00228446 0.00222941
Toxoplasma gondii cyclic nucleotide-binding domain-containing protein 0.00368632 0.00469944 0.00723974
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.00706599 0.015597 0.0248481
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.04587 0.140718 0.140288
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Schistosoma mansoni camp-dependent protein kinase type I-beta regulatory subunit 0.00368632 0.00469944 0.00464452
Brugia malayi G-protein coupled receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Brugia malayi Sodium:neurotransmitter symporter family protein 0.04587 0.140718 0.140671
Echinococcus multilocularis SWI:SNF matrix associated 0.00618448 0.0127546 0.0122604
Schistosoma mansoni voltage-gated potassium channel 0.0286718 0.0852639 0.0852134
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.00583583 0.0116304 0.0111356
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Schistosoma mansoni biogenic amine (5HT) receptor 0.0379341 0.11513 0.115081
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0297584 0.0887674 0.0883112
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.00936412 0.0230072 0.022518
Loa Loa (eye worm) variant SH3 domain-containing protein 0.00280603 0.001861 0.00136125
Echinococcus multilocularis cyclin t1 0.0062898 0.0130942 0.0126001
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0108361 0.0277536 0.0272668
Echinococcus multilocularis neuropeptide FF receptor 2 0.0350178 0.105726 0.105279
Plasmodium falciparum cysteine proteinase falcipain 1 0.099263 0.312881 0.538594
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.00368632 0.00469944 0.00723974
Trypanosoma brucei protein kinase, putative 0.00624944 0.0129641 0.0205145
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.00936412 0.0230072 0.728152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0297584 0.0887674 0.0883112
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.00551764 0.0106045 0.0101091
Brugia malayi Protein kinase domain containing protein 0.033252 0.100032 0.0999827
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis STE family protein kinase 0.00402932 0.00580544 0.00914666
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.00430629 0.00669849 0.00620116
Echinococcus granulosus peptide allatostatin:somatostatin 0.0350178 0.105726 0.105279
Schistosoma mansoni biogenic amine receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.03044 0.0909652 0.0905101
Giardia lamblia Cathepsin B precursor 0.153556 0.487948 1
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Schistosoma mansoni serine/threonine protein kinase 0.0056673 0.011087 0.0110324
Echinococcus granulosus Lysosomal Pro X carboxypeptidase 0.0456793 0.140104 0.139673
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.00719882 0.0160253 0.0155327
Loa Loa (eye worm) STE/STE20/PAKA protein kinase 0.00238718 0.000510436 0.0000100072
Echinococcus multilocularis dro:myosuppressin receptor 0.0350178 0.105726 0.105279
Onchocerca volvulus 0.00358585 0.00437548 0.00671013
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0350178 0.105726 0.105279
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Entamoeba histolytica protein kinase domain containing protein 0.00309933 0.00280674 0.00483509
Echinococcus granulosus cathepsin l cysteine peptidase 0.182258 0.580494 0.580284
Echinococcus granulosus mitogen activated protein kinase 3 0.0057134 0.0112357 0.0107406
Trichomonas vaginalis AGC family protein kinase 0.0101101 0.0254124 0.0429522
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0426756 0.130418 0.266528
Plasmodium vivax cyclin dependent kinase binding protein, putative 0.0062898 0.0130942 0.0217137
Plasmodium falciparum serine repeat antigen 6 0.0426756 0.130418 0.223999
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0416292 0.127044 0.126996
Echinococcus granulosus nAChR subunit 0.00269638 0.00150744 0.00100751
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis glycine receptor subunit beta 0.00269638 0.00150744 0.00100751
Schistosoma mansoni serine/threonine protein kinase 0.00484401 0.00843236 0.00837765
Loa Loa (eye worm) AGC/AKT protein kinase 0.0107418 0.0274494 0.0269624
Echinococcus granulosus cathepsin b 0.312359 1 1
Schistosoma mansoni serine/threonine protein kinase 0.00484401 0.00843236 0.00837765
Onchocerca volvulus 0.182258 0.580494 1
Brugia malayi Cyclin C 0.0106516 0.0271588 0.0271051
Onchocerca volvulus 0.0350178 0.105726 0.18145
Brugia malayi Immunoglobulin I-set domain containing protein 0.0116864 0.0304951 0.0304416
Schistosoma mansoni nephrin 0.00547508 0.0104672 0.0104126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Leishmania major protein kinase, putative 0.00309933 0.00280674 0.00379604
Leishmania major protein kinase A catalytic subunit isoform 2 0.0030568 0.0026696 0.00357031
Echinococcus granulosus 7TM GPCR rhodopsin 0.0350178 0.105726 0.105279
Onchocerca volvulus 0.12567 0.398031 0.685414
Brugia malayi prolyl oligopeptidase family protein 0.0105036 0.0266814 0.0266277
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.00269638 0.00150744 0.00145234
Echinococcus granulosus cyclic nucleotide gated cation channel 0.00368632 0.00469944 0.00420111
Echinococcus granulosus sex peptide receptor 0.0350178 0.105726 0.105279
Entamoeba histolytica protein kinase, putative 0.00301562 0.00253681 0.0043701
Onchocerca volvulus 0.0114839 0.0298423 0.0506176
Toxoplasma gondii cyclin, N-terminal domain-containing protein 0.0062898 0.0130942 0.0217137
Leishmania major hypothetical protein, conserved 0.00371334 0.00478657 0.00705472
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0108361 0.0277536 0.0272668
Trichomonas vaginalis CAMK family protein kinase 0.00426539 0.00656665 0.0104591
Loa Loa (eye worm) hypothetical protein 0.0339089 0.10215 0.101701
Echinococcus granulosus serine:threonine protein kinase 3 0.0123321 0.0325773 0.0320929
Brugia malayi Stress-activated protein kinase jnk-1 0.0108261 0.0277213 0.0276676
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus granulosus mitogen activated protein kinase 0.0057134 0.0112357 0.0107406
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0238562 0.0697363 0.119374
Trichomonas vaginalis cyclin D, putative 0.0062898 0.0130942 0.0217137
Onchocerca volvulus 0.00581734 0.0115708 0.0191157
Brugia malayi G protein-coupled receptor F59B2.13 0.0350178 0.105726 0.105677
Echinococcus multilocularis serotonin receptor 0.0379341 0.11513 0.114686
Entamoeba histolytica protein kinase, putative 0.0101101 0.0254124 0.0437773
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.00309933 0.00280674 0.00230746
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0114839 0.0298423 1
Echinococcus granulosus serine:threonine protein kinase MARK2 0.00822065 0.0193202 0.0188292
Trichomonas vaginalis conserved hypothetical protein 0.00368632 0.00469944 0.00723974
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0124779 0.0330476 0.0325635
Loa Loa (eye worm) hypothetical protein 0.0297584 0.0887674 0.0883112
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.00238718 0.000510436 0.0000100072
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Entamoeba histolytica tubulin family protein 0.0237345 0.0693438 0.119457
Trichomonas vaginalis STE family protein kinase 0.00402932 0.00580544 0.00914666
Echinococcus multilocularis orexin receptor type 2 0.0350178 0.105726 0.105279
Echinococcus granulosus cyclic nucleotide gated cation channel 0.00583583 0.0116304 0.0111356
Echinococcus multilocularis cathepsin L cysteine protease 0.182258 0.580494 0.580284
Brugia malayi cathepsin L-like cysteine proteinase 0.0426756 0.130418 0.13037
Trypanosoma brucei cyclic nucleotide-binding domain containing protein, putative 0.00368632 0.00469944 0.00691131
Brugia malayi Protein kinase domain containing protein 0.00358585 0.00437548 0.00432054
Brugia malayi Protein kinase domain containing protein 0.00511295 0.00929954 0.00924488
Loa Loa (eye worm) ACC-1 protein 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Trypanosoma brucei cysteine peptidase C (CPC) 0.153556 0.487948 0.802309
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.099263 0.312881 0.312537
Loa Loa (eye worm) integrin alpha pat-2 0.00612794 0.0125723 0.0120779
Onchocerca volvulus 0.182258 0.580494 1
Schistosoma mansoni voltage-gated potassium channel 0.0286718 0.0852639 0.0852134
Trichomonas vaginalis cyclins, putative 0.0491228 0.151207 0.259842
Brugia malayi Carboxylesterase family protein 0.0114839 0.0298423 0.0297887
Schistosoma mansoni kinase 0.0521877 0.16109 0.161043
Brugia malayi Carboxylesterase family protein 0.0114839 0.0298423 0.0297887
Giardia lamblia Serine peptidase, putative 0.0339089 0.10215 0.208536
Trichomonas vaginalis adenylate cyclase type IX, putative 0.00266606 0.00140966 0.00156765
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.00618448 0.0127546 0.0122604
Echinococcus granulosus acetylcholinesterase 0.0679658 0.211965 0.211571
Entamoeba histolytica hypothetical protein 0.0426756 0.130418 0.224668
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.00745194 0.0168415 0.0167872
Plasmodium falciparum proteasome subunit beta type-5 0.00569812 0.0111864 0.0184243
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0134094 0.0360512 0.0355685
Onchocerca volvulus Cathepsin F homolog 0.182258 0.580494 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0114839 0.0298423 1
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.00684915 0.0148978 0.0144046
Plasmodium vivax plasmepsin IV, putative 0.0383289 0.116403 0.199834
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057134 0.0112357 0.0107406
Mycobacterium ulcerans hydrolase 0.00936412 0.0230072 0.756323
Loa Loa (eye worm) hypothetical protein 0.0114839 0.0298423 0.0293565
Loa Loa (eye worm) TK/EPH protein kinase 0.00535127 0.010068 0.00957235
Trichomonas vaginalis CMGC family protein kinase 0.00480698 0.00831297 0.01347
Onchocerca volvulus 0.00269638 0.00150744 0.00176532
Trypanosoma cruzi major cysteine proteinase, putative 0.0426756 0.130418 0.129983
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.00246218 0.000752262 0.000251955
Brugia malayi protein-tyrosine kinase 0.00603699 0.0122791 0.0122246
Trichomonas vaginalis cyclin A, putative 0.0062898 0.0130942 0.0217137
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0105036 0.0266814 0.0266277
Trichomonas vaginalis CAMK family protein kinase 0.0406902 0.124017 0.212961
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Giardia lamblia Cyclin B-like protein 0.0062898 0.0130942 0.0258362
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Schistosoma mansoni hypothetical protein 0.0031077 0.00283372 0.0027787
Schistosoma mansoni voltage-gated potassium channel 0.00481557 0.00834066 0.00828594
Brugia malayi Dopamine receptor protein 2 0.0350178 0.105726 0.105677
Schistosoma mansoni neuropeptide F-like receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus multilocularis carboxylesterase 5A 0.0679658 0.211965 0.211571
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Echinococcus multilocularis epidermal growth factor receptor 0.0522689 0.161351 0.160931
Leishmania major cyclin 0.0491228 0.151207 0.248054
Trichomonas vaginalis conserved hypothetical protein 0.00287163 0.00207251 0.00271051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis cyclin dependent kinase 0.00706599 0.015597 0.0151042
Brugia malayi Tyrosine-protein kinase abl-1 0.0118633 0.0310656 0.0310121
Entamoeba histolytica hypothetical protein 0.0040655 0.00592209 0.0102018
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0106516 0.0271588 0.0266717
Echinococcus multilocularis Dipeptidyl peptidase 9 0.00811809 0.0189894 0.0184983
Plasmodium falciparum serine repeat antigen 7 0.0426756 0.130418 0.223999
Mycobacterium ulcerans epoxide hydrolase EphA 0.00632282 0.0132007 0.40671
Onchocerca volvulus 0.00950888 0.023474 0.039638
Toxoplasma gondii serine carboxypeptidase s28 protein 0.0339089 0.10215 0.175261
Echinococcus multilocularis Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Trypanosoma brucei cAMP binding protein, putative 0.00371334 0.00478657 0.00705472
Brugia malayi Dopamine receptor protein 1 0.0350178 0.105726 0.105677
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Echinococcus granulosus Glutaredoxin protein 5 0.00500833 0.0089622 0.00846601
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114839 0.0298423 0.0297887
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0426756 0.130418 0.223999
Loa Loa (eye worm) hypothetical protein 0.0443762 0.135902 0.135469
Loa Loa (eye worm) hypothetical protein 0.0491228 0.151207 0.150782
Loa Loa (eye worm) cAMP-dependent protein kinase regulatory subunit 0.00368632 0.00469944 0.00420111
Trichomonas vaginalis adenylate cyclase type IX, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) hypothetical protein 0.0164023 0.0457014 0.0452236
Schistosoma mansoni pyruvate dehydrogenase 0.00561136 0.0109066 0.0108521
Schistosoma mansoni tubulin subunit beta 0.0237345 0.0693438 0.0692925
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.00404895 0.00586872 0.00537097
Loa Loa (eye worm) hypothetical protein 0.00988112 0.0246743 0.0241859
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Giardia lamblia Cathepsin B precursor 0.0426756 0.130418 0.266528
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0426756 0.130418 0.266528
Brugia malayi hypothetical protein 0.00950888 0.023474 0.0234201
Treponema pallidum sodium- and chloride- dependent transporter 0.04587 0.140718 1
Echinococcus granulosus Immunoglobulin 0.00452414 0.00740096 0.00690398
Brugia malayi Dopamine receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trypanosoma cruzi hypothetical protein, conserved 0.0062898 0.0130942 0.0126001
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.00269638 0.00150744 0.00100751
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0350178 0.105726 0.105677
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.267042 0.853876 0.853803
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Trichomonas vaginalis conserved hypothetical protein 0.0062898 0.0130942 0.0217137
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Brugia malayi follicle stimulating hormone receptor 0.0350178 0.105726 0.105677
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0108261 0.0277213 0.0272345
Schistosoma mansoni serine/threonine protein kinase 0.0855307 0.268603 0.268562
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) hypothetical protein 0.138316 0.438808 0.438527
Schistosoma mansoni growth factor receptor-bound protein 0.00280603 0.001861 0.00180593
Trichomonas vaginalis AGC family protein kinase 0.0101101 0.0254124 0.0429522
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.00269638 0.00150744 0.00100751
Schistosoma mansoni serine/threonine protein kinase 0.00608225 0.012425 0.0123705
Echinococcus granulosus integrin alpha ps 0.00612794 0.0125723 0.0120779
Brugia malayi ephrin receptor 1 precursor 0.00320274 0.00314015 0.00308515
Leishmania major cathepsin L-like protease 0.190805 0.608055 1
Entamoeba histolytica protein kinase, putative 0.00328095 0.00339235 0.00584391
Echinococcus granulosus protein kinase C gamma type 0.00744502 0.0168192 0.0163269
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.00593037 0.0119353 0.0114406
Toxoplasma gondii AGC kinase 0.0030568 0.0026696 0.00373998
Echinococcus multilocularis tyrosine protein kinase Src42A 0.00719882 0.0160253 0.0155327
Leishmania major protein kinase, putative 0.00404489 0.00585564 0.00881435
Loa Loa (eye worm) cyclin C 0.0106516 0.0271588 0.0266717
Schistosoma mansoni tyrosine kinase 0.0326182 0.0979889 0.0979391
Echinococcus multilocularis glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Brugia malayi Variant SH3 domain containing protein 0.00294869 0.002321 0.00226595
Entamoeba histolytica tubulin family protein 0.0237345 0.0693438 0.119457
Plasmodium vivax proteasome subunit beta type-5, putative 0.00569812 0.0111864 0.0184243
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) AGC/PKN protein kinase 0.00551764 0.0106045 0.0101091
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.152186
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Schistosoma mansoni protein kinase 0.00309933 0.00280674 0.00275172
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0260058 0.0766673 0.076205
Echinococcus multilocularis serine:threonine protein kinase N2 0.00551764 0.0106045 0.0101091
Giardia lamblia Cathepsin L precursor 0.0426756 0.130418 0.266528
Brugia malayi Protein kinase domain containing protein 0.0130632 0.0349347 0.0348814
Trypanosoma cruzi Flagellar Member 6 0.00368632 0.00469944 0.00420111
Schistosoma mansoni serine/threonine protein kinase 0.00551764 0.0106045 0.0105499
Trichomonas vaginalis AGC family protein kinase 0.00388268 0.0053326 0.00833141
Plasmodium falciparum cAMP-dependent protein kinase regulatory subunit 0.00368632 0.00469944 0.00723974
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0350178 0.105726 0.105677
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Entamoeba histolytica cyclin family protein 0.0229919 0.0669495 0.115332
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0426756 0.130418 0.223999
Trypanosoma cruzi 5'-AMP-activated protein kinase subunit beta, putative 0.00324397 0.00327312 0.00277407
Echinococcus granulosus cAMP dependent protein kinase type I beta 0.00368632 0.00469944 0.00420111
Loa Loa (eye worm) TK/FER protein kinase 0.00358585 0.00437548 0.00387698
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.00269638 0.00150744 0.00145234
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.00936412 0.0230072 0.0229533
Entamoeba histolytica serine carboxypeptidase (S28) family protein 0.0339089 0.10215 0.175972
Echinococcus multilocularis glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Brugia malayi GnHR receptor homolog 0.0475251 0.146056 0.146008
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0114839 0.0298423 0.0293565
Loa Loa (eye worm) norepinephrine transporter 0.04587 0.140718 0.140288
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.00269638 0.00150744 0.00145234
Onchocerca volvulus Cathepsin L homolog 0.182258 0.580494 1
Echinococcus granulosus insulin receptor 0.033252 0.100032 0.0995818
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.00506665 0.00915025 0.0142371
Leishmania major protein kinase, putative 0.00484401 0.00843236 0.0130555
Echinococcus granulosus ras gtpase 0.00459662 0.00763466 0.0071378
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.00593037 0.0119353 0.0114406
Leishmania major mitotic cyclin, putative 0.0062898 0.0130942 0.0207286
Brugia malayi casein kinase 1, delta 0.00238408 0.000500434 0.000445284
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Brugia malayi Tyrosine-protein kinase abl-1 0.0114944 0.0298762 0.0298227
Brugia malayi Cyclin, N-terminal domain containing protein 0.0062898 0.0130942 0.0130398
Schistosoma mansoni integrin alpha-ps 0.00319058 0.00310096 0.00304595
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis glucosylceramidase, putative 0.0133443 0.0358412 0.0609331
Echinococcus granulosus roundabout 2 0.00640959 0.0134805 0.0129866
Echinococcus granulosus protein kinase shaggy 0.00745194 0.0168415 0.0163493
Trichomonas vaginalis AGC family protein kinase 0.00551764 0.0106045 0.0174209
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Mycobacterium leprae PROBABLE HYDROLASE 0.00936412 0.0230072 0.779158
Echinococcus multilocularis cyclin k 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis tubulin epsilon chain, putative 0.0237345 0.0693438 0.118697
Brugia malayi Cyclin, N-terminal domain containing protein 0.0147171 0.0402678 0.0402149
Brugia malayi hypothetical protein 0.00783841 0.0180877 0.0180335
Loa Loa (eye worm) 5'-AMP-activated protein kinase 0.00324397 0.00327312 0.00277407
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Schistosoma mansoni neuropathy target esterase/swiss cheese-related protein 0.00368632 0.00469944 0.00464452
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.00269638 0.00150744 0.00100751
Loa Loa (eye worm) aspartyl protease 6 0.00950888 0.023474 0.0229851
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.00583583 0.0116304 0.0111356
Trypanosoma brucei Flagellar Member 6 0.00368632 0.00469944 0.00691131
Schistosoma mansoni cyclin k 0.0062898 0.0130942 0.0130398
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0350178 0.105726 0.105677
Echinococcus granulosus tyrosine protein kinase Btk29A 0.010323 0.0260992 0.0256116
Schistosoma mansoni dihydrofolate reductase 0.0112626 0.0291288 0.0290752
Schistosoma mansoni cyclin G 0.0062898 0.0130942 0.0130398
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Brugia malayi dihydrofolate reductase family protein 0.0112626 0.0291288 0.0290752
Echinococcus granulosus patatin phospholipase domain containing protein 0.00368632 0.00469944 0.00420111
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0631579 0.196462 0.19606
Echinococcus granulosus neuropeptide FF receptor 2 0.0350178 0.105726 0.105279
Echinococcus granulosus tyrosine protein kinase Src64B 0.00719882 0.0160253 0.0155327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0350178 0.105726 0.105677
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.00266606 0.00140966 0.00135456
Trichomonas vaginalis cyclin B, putative 0.0491228 0.151207 0.259842
Leishmania major regulatory subunit of protein kinase a-like protein 0.00368632 0.00469944 0.00691131
Brugia malayi larval opioid receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni opsin-like receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.312359 1 1
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.00583583 0.0116304 0.0111356
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0475169 0.146029 0.145601
Schistosoma mansoni tyrosine kinase 0.0205516 0.0590808 0.0590289
Loa Loa (eye worm) hypothetical protein 0.00905722 0.0220177 0.021528
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.00618448 0.0127546 0.0211282
Echinococcus granulosus single minded 2 0.00266606 0.00140966 0.00090968
Echinococcus multilocularis cyclin G2 0.0062898 0.0130942 0.0126001
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Plasmodium vivax rap guanine nucleotide exchange factor, putative 0.00368632 0.00469944 0.00723974
Trichomonas vaginalis AGC family protein kinase 0.00689943 0.0150599 0.0251029
Brugia malayi Matrixin family protein 0.00768843 0.0176041 0.0175499
Brugia malayi GTP-binding protein 0.00459662 0.00763466 0.00757991
Trichomonas vaginalis adenylate cyclase type, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus epidermal growth factor receptor 0.0522689 0.161351 0.160931
Trypanosoma brucei cyclin dependent kinase-binding protein, putative 0.0062898 0.0130942 0.0207286
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.00368632 0.00469944 0.00464452
Echinococcus multilocularis cyclin dependent kinase 9 0.00458499 0.00759715 0.00710027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Trichomonas vaginalis glucosylceramidase, putative 0.00771694 0.017696 0.0296478
Loa Loa (eye worm) kelch domain-containing protein family protein 0.00480528 0.00830747 0.00781095
Brugia malayi Protein kinase domain containing protein 0.0357744 0.108166 0.108117
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.00689943 0.0150599 0.0251029
Echinococcus granulosus hyperpolarization activated cyclic 0.00583583 0.0116304 0.0111356
Echinococcus multilocularis cyclin A3 4 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.00415479 0.00621002 0.00571244
Plasmodium falciparum plasmepsin III 0.00950888 0.023474 0.03961
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Echinococcus granulosus dro:myosuppressin receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Schistosoma mansoni cathepsin F (C01 family) 0.12567 0.398031 0.397998
Echinococcus multilocularis NCK adaptor protein 0.00280603 0.001861 0.00136125
Trypanosoma cruzi putative prolyl carboxypeptidase, putative 0.0339089 0.10215 0.101701
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0114839 0.0298423 0.0505899
Trichomonas vaginalis adenylate cyclase type, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Integrin beta pat-3 precursor 0.0290669 0.0865379 0.0864875
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0383289 0.116403 0.11596
Entamoeba histolytica cysteine protease, putative 0.0426756 0.130418 0.224668
Giardia lamblia Cyclin A 0.0229919 0.0669495 0.136321
Trypanosoma cruzi cyclic nucleotide-binding domain containing protein, putative 0.00368632 0.00469944 0.00420111
Echinococcus multilocularis mitogen activated protein kinase 0.0057134 0.0112357 0.0107406
Loa Loa (eye worm) AGC/PKA protein kinase 0.0030568 0.0026696 0.00217025
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Schistosoma mansoni cyclins 0.0229919 0.0669495 0.066898
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Trichomonas vaginalis cyclin B, putative 0.0491228 0.151207 0.259842
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0350178 0.105726 0.105279
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0123321 0.0325773 0.0320929
Echinococcus granulosus carboxylesterase 5A 0.0679658 0.211965 0.211571
Loa Loa (eye worm) hypothetical protein 0.0107729 0.0275497 0.0270628
Loa Loa (eye worm) hypothetical protein 0.0379341 0.11513 0.114686
Schistosoma mansoni serine/threonine protein kinase 0.0087495 0.0210254 0.0209714
Trichomonas vaginalis cyclins, putative 0.0491228 0.151207 0.259842
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0565873 0.175276 0.174863
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.00706599 0.015597 0.0151042
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0297584 0.0887674 0.0887172
Schistosoma mansoni histamine h1 receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Loa Loa (eye worm) hypothetical protein 0.00480528 0.00830747 0.00781095
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.312359 1 1
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.00583583 0.0116304 0.0115759
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0426756 0.130418 0.13037
Schistosoma mansoni tyrosine kinase 0.0108361 0.0277536 0.0277
Brugia malayi Cyclic-nucleotide gated cation channel, C. elegans tax-4 ortholog 0.00368632 0.00469944 0.00464452
Schistosoma mansoni hypothetical protein 0.0062898 0.0130942 0.0130398
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Mycobacterium leprae proteasome (beta subunit) PrcB 0.00569812 0.0111864 0.352708
Giardia lamblia Hypothetical protein 0.0229919 0.0669495 0.136321
Schistosoma mansoni serine/threonine protein kinase 0.00506665 0.00915025 0.00909558
Entamoeba histolytica protein kinase, putative 0.00388268 0.0053326 0.00918631
Echinococcus granulosus BC026374 protein S09 family 0.0114839 0.0298423 0.0293565
Brugia malayi Immunoglobulin I-set domain containing protein 0.0354179 0.107016 0.106967
Leishmania major hypothetical protein, unknown function 0.00368632 0.00469944 0.00691131
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Giardia lamblia Kinase, CMGC CDK 0.00706599 0.015597 0.0309707
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0108261 0.0277213 0.0272345
Loa Loa (eye worm) hypothetical protein 0.0031077 0.00283372 0.00233446
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus granulosus cAMP dependent protein kinase regulatory 0.00368632 0.00469944 0.00420111
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Brugia malayi Immunoglobulin I-set domain containing protein 0.00462485 0.0077257 0.00767095
Mycobacterium ulcerans hypothetical protein 0.00368632 0.00469944 0.10363
Schistosoma mansoni tyrosine kinase 0.00719882 0.0160253 0.015971
Loa Loa (eye worm) TK/ALK protein kinase 0.0130556 0.0349102 0.034427
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) BEN-1 protein 0.0237345 0.0693438 0.0688779
Echinococcus granulosus tyrosine protein kinase Blk 0.00603699 0.0122791 0.0117845
Echinococcus granulosus 7tm_1 domain containing protein 0.0350178 0.105726 0.105279
Schistosoma mansoni voltage-gated potassium channel 0.00850189 0.020227 0.0201729
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Toxoplasma gondii aspartyl protease ASP3 0.00950888 0.023474 0.03961
Echinococcus granulosus nervana 2 0.00500833 0.0089622 0.00846601
Brugia malayi Dihydrofolate reductase 0.0112626 0.0291288 0.0290752
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.00269638 0.00150744 0.00145234
Echinococcus granulosus cathepsin L 0.099263 0.312881 0.312537
Leishmania major protein kinase, putative 0.0101101 0.0254124 0.0410037
Brugia malayi cathepsin L precursor 0.0426756 0.130418 0.13037
Echinococcus granulosus CDC7 cell division cycle 7 0.00480698 0.00831297 0.00781645
Trichomonas vaginalis AGC family protein kinase 0.0107418 0.0274494 0.0464642
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Echinococcus multilocularis serine:threonine protein kinase 38 0.00551764 0.0106045 0.0101091
Trichomonas vaginalis cyclins, putative 0.0062898 0.0130942 0.0217137
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Loa Loa (eye worm) hypothetical protein 0.00581734 0.0115708 0.0110759
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057134 0.0112357 0.0107406
Brugia malayi prolyl oligopeptidase family protein 0.00811809 0.0189894 0.0189353
Echinococcus multilocularis glycine receptor subunit alpha 1 0.00269638 0.00150744 0.00100751
Plasmodium vivax unspecified product 0.0426756 0.130418 0.223999
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.00327957 0.00338792 0.00288893
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.190805 0.608055 1
Giardia lamblia Proteasome subunit beta type 5 precursor 0.00569812 0.0111864 0.0219223
Schistosoma mansoni serine/threonine protein kinase 0.00324612 0.00328006 0.00322506
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0229919 0.0669495 0.0664823
Trichomonas vaginalis STE family protein kinase 0.00689943 0.0150599 0.0251029
Echinococcus multilocularis Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Echinococcus granulosus Upstream activation factor subunit UAF30 0.00618448 0.0127546 0.0122604
Onchocerca volvulus 0.0350178 0.105726 0.18145
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.00903343 0.0219409 0.0214512
Schistosoma mansoni hypothetical protein 0.00368632 0.00469944 0.00464452
Giardia lamblia Kinase, AGC PKA 0.00616602 0.0126951 0.0250175
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.00266606 0.00140966 0.00156765
Trypanosoma cruzi cysteine proteinase, putative 0.099263 0.312881 0.312537
Loa Loa (eye worm) hypothetical protein 0.00593037 0.0119353 0.0114406
Echinococcus multilocularis neuropeptide receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.182258 0.580494 1
Trichomonas vaginalis AGC family protein kinase 0.0101101 0.0254124 0.0429522
Plasmodium falciparum serine repeat antigen 9 0.0426756 0.130418 0.223999
Schistosoma mansoni vesicular amine transporter 0.00667366 0.014332 0.0142776
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.00402932 0.00580544 0.00530766
Trichomonas vaginalis cyclin B3, putative 0.0229919 0.0669495 0.114569
Echinococcus multilocularis cyclins 0.0229919 0.0669495 0.0664823
Mycobacterium ulcerans regulatory protein 0.00368632 0.00469944 0.10363
Brugia malayi Sodium:neurotransmitter symporter family protein 0.138316 0.438808 0.438777
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.00462738 0.00773384 0.00767909
Brugia malayi Serine/threonine-protein kinase Nek7 0.0142865 0.0388794 0.0388263
Schistosoma mansoni cathepsin C 0.0426756 0.130418 0.13037
Loa Loa (eye worm) hypothetical protein 0.0062898 0.0130942 0.0126001
Loa Loa (eye worm) hypothetical protein 0.0297584 0.0887674 0.0883112
Brugia malayi p21/Cdc42/Rac1-activated kinase 0.00238718 0.000510436 0.000455287
Schistosoma mansoni memapsin-2 (A01 family) 0.00950888 0.023474 0.0234201
Schistosoma mansoni tyrosine kinase 0.00358585 0.00437548 0.00432054
Schistosoma mansoni cell polarity protein 0.00459662 0.00763466 0.00757991
Echinococcus granulosus glycine receptor subunit beta 0.00269638 0.00150744 0.00100751
Schistosoma mansoni serine/threonine protein kinase 0.0030568 0.0026696 0.00261457
Schistosoma mansoni protein kinase 0.00238408 0.000500434 0.000445284
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0426756 0.130418 0.13037
Entamoeba histolytica protein kinase, putative 0.00506665 0.00915025 0.0157629
Echinococcus multilocularis cGMP dependent protein kinase 1 0.00484401 0.00843236 0.0079359
Echinococcus granulosus cyclins 0.0062898 0.0130942 0.0126001
Plasmodium falciparum serine repeat antigen 5 0.0426756 0.130418 0.223999
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0426756 0.130418 0.223999
Echinococcus multilocularis integrin alpha ps 0.00612794 0.0125723 0.0120779
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.00269638 0.00150744 0.00100751
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0062898 0.0130942 0.0217137
Onchocerca volvulus 0.00368632 0.00469944 0.00726867
Entamoeba histolytica protein kinase domain containing protein 0.00506665 0.00915025 0.0157629
Echinococcus granulosus fmrfamide receptor 0.0350178 0.105726 0.105279
Plasmodium falciparum cysteine proteinase falcipain 3 0.182258 0.580494 1
Brugia malayi map kinase activated protein kinase protein 2 0.0315703 0.0946098 0.0945599
Plasmodium falciparum cysteine proteinase falcipain 2a 0.182258 0.580494 1
Onchocerca volvulus 0.0103643 0.0262321 0.0443933
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.00269638 0.00150744 0.00100751
Echinococcus granulosus N chimaerin 0.00294869 0.002321 0.00182148
Echinococcus granulosus voltage gated potassium channel 0.00850189 0.020227 0.0197364
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.00368632 0.00469944 0.00726867
Brugia malayi Cation transporter family protein 0.00269638 0.00150744 0.00145234
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.099263 0.312881 0.514161
Loa Loa (eye worm) hypothetical protein 0.00269638 0.00150744 0.00100751
Entamoeba histolytica protein kinase, putative 0.00439278 0.00697741 0.0120198
Onchocerca volvulus Serine\/threonine kinase homolog 0.0855307 0.268603 0.462266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Echinococcus multilocularis cyclin B3 1 0.0229919 0.0669495 0.0664823
Trichomonas vaginalis cyclin D, putative 0.0229919 0.0669495 0.114569
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis dihydrofolate reductase 0.0112626 0.0291288 0.0286427
Trypanosoma brucei beta tubulin 0.0237345 0.0693438 0.113312
Onchocerca volvulus 0.0350178 0.105726 0.18145
Loa Loa (eye worm) hypothetical protein 0.0426756 0.130418 0.129983
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.00430629 0.00669849 0.0102016
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Trichomonas vaginalis CAMK family protein kinase 0.0406902 0.124017 0.212961
Schistosoma mansoni alpha-1 adrenergic receptor 0.0350178 0.105726 0.105677
Loa Loa (eye worm) hypothetical protein 0.188368 0.600196 0.599995
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.182258 0.580494 1
Echinococcus granulosus somatostatin receptor 0.0350178 0.105726 0.105279
Entamoeba histolytica casein kinase, putative 0.00238408 0.000500434 0.000862083
Brugia malayi serine/threonine-protein kinase 6 0.0101101 0.0254124 0.0253587
Echinococcus multilocularis cyclin dependent kinase 7 0.00608225 0.012425 0.0119305
Loa Loa (eye worm) hypothetical protein 0.00462485 0.0077257 0.00722888
Trichomonas vaginalis spcc417.12 protein, putative 0.0114839 0.0298423 0.0505899
Schistosoma mansoni serine/threonine protein kinase 0.00388268 0.0053326 0.00527771
Giardia lamblia Hypothetical protein 0.0062898 0.0130942 0.0258362
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.00583583 0.0116304 0.0111356
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0350178 0.105726 0.105677
Schistosoma mansoni amine GPCR 0.0350178 0.105726 0.105677
Trypanosoma cruzi cyclin 9, putative 0.0062898 0.0130942 0.0126001
Onchocerca volvulus 0.0350178 0.105726 0.18145
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis CMGC family protein kinase 0.00706599 0.015597 0.0260289
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0105956 0.0269782 0.0269245
Echinococcus multilocularis tyrosine protein kinase Fgr 0.00719882 0.0160253 0.0155327
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0114839 0.0298423 0.0297887
Entamoeba histolytica serine/threonine protein kinase, putative 0.0855307 0.268603 0.462714
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.00950888 0.023474 0.0234201
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0426756 0.130418 0.223999
Plasmodium vivax amine transporter, putative 0.0297584 0.0887674 0.152186
Loa Loa (eye worm) TK/ROR protein kinase 0.00279187 0.00181533 0.00131555
Toxoplasma gondii cathepsin B 0.153556 0.487948 0.840436
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.00269638 0.00150744 0.00100751
Entamoeba histolytica protein kinase, putative 0.00745194 0.0168415 0.0290124
Echinococcus granulosus Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Brugia malayi AKH receptor 0.0350178 0.105726 0.105677
Echinococcus multilocularis dual specificity testis specific protein kinase 0.00938104 0.0230618 0.0225726
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.00269638 0.00150744 0.00145234
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.00308507 0.00276074 0.00226143
Toxoplasma gondii hypothetical protein 0.0167022 0.0466683 0.0796007
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0426756 0.130418 0.129983
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0030568 0.0026696 0.00217025
Schistosoma mansoni nAChR subunit 0.00269638 0.00150744 0.00145234
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0229919 0.0669495 0.0664823
Trypanosoma cruzi major cysteine proteinase, putative 0.0512233 0.15798 0.157559
Trypanosoma cruzi SNF1-related protein kinase regulatory subunit beta, putative 0.00324397 0.00327312 0.00277407
Loa Loa (eye worm) AUR protein kinase 0.0101101 0.0254124 0.0249245
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.00430629 0.00669849 0.0106864
Echinococcus multilocularis tyrosine protein kinase Src64B 0.00719882 0.0160253 0.0155327
Trichomonas vaginalis CMGC family protein kinase 0.00706599 0.015597 0.0260289
Echinococcus multilocularis g protein coupled receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0350178 0.105726 0.105279
Leishmania major cathepsin L-like protease 0.182258 0.580494 0.954635
Loa Loa (eye worm) hypothetical protein 0.0565873 0.175276 0.174863
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0333527 0.100357 0.0999067
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Trichomonas vaginalis lysosomal pro-X carboxypeptidase, putative 0.0339089 0.10215 0.175261
Brugia malayi Papain family cysteine protease containing protein 0.0426756 0.130418 0.13037
Echinococcus multilocularis cyclin dependent kinase 9 0.00404895 0.00586872 0.00537097
Echinococcus multilocularis protein kinase c iota type 0.00682213 0.0148107 0.0143174
Loa Loa (eye worm) hypothetical protein 0.0679658 0.211965 0.211571
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus epidermal growth factor receptor 0.0326182 0.0979889 0.0975372
Leishmania major dihydrofolate reductase-thymidylate synthase 0.00430629 0.00669849 0.0102016
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.00850189 0.020227 0.0201729
Echinococcus granulosus neuropeptides capa receptor 0.0350178 0.105726 0.105279
Schistosoma mansoni cathepsin D (A01 family) 0.116695 0.369091 0.369056
Toxoplasma gondii beta-1 tubulin, putative 0.0237345 0.0693438 0.118697
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Trichomonas vaginalis CMGC family protein kinase 0.0057134 0.0112357 0.0185092
Entamoeba histolytica protein kinase, putative 0.010526 0.0267536 0.0460876
Plasmodium vivax serine-repeat antigen (SERA) 0.0426756 0.130418 0.223999
Brugia malayi Protein kinase domain containing protein 0.00358585 0.00437548 0.00432054
Brugia malayi Cytochrome P450 family protein 0.00278484 0.00179267 0.00173759
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.00618448 0.0127546 0.0122604
Schistosoma mansoni family S28 unassigned peptidase (S28 family) 0.0456793 0.140104 0.140056
Echinococcus granulosus cyclin b3 0.0229919 0.0669495 0.0664823
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.00503614 0.00905187 0.014744
Trichomonas vaginalis conserved hypothetical protein 0.00266606 0.00140966 0.00156765
Echinococcus multilocularis Immunoglobulin 0.00452414 0.00740096 0.00690398
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.010526 0.0267536 0.0262663
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.00706599 0.015597 0.0260289
Entamoeba histolytica cell division protein kinase 2, putative 0.00706599 0.015597 0.0268686
Schistosoma mansoni thyroid hormone receptor 0.00464976 0.00780602 0.00775128
Echinococcus multilocularis expressed conserved protein 0.00484401 0.00843236 0.0079359
Leishmania major cyclin 9, putative 0.0062898 0.0130942 0.0207286
Onchocerca volvulus 0.00267598 0.00144167 0.00165194
Trichomonas vaginalis cyclins, putative 0.0229919 0.0669495 0.114569
Echinococcus multilocularis hyperpolarization activated cyclic 0.00583583 0.0116304 0.0111356
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Brugia malayi Cytochrome P450 family protein 0.00311638 0.00286171 0.00280669
Echinococcus multilocularis Lysosomal Pro X carboxypeptidase 0.188368 0.600196 0.599995
Schistosoma mansoni serine/threonine protein kinase 0.0101101 0.0254124 0.0253587
Trichomonas vaginalis adenylate cyclase type IX, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis adenylate cyclase, putative 0.00266606 0.00140966 0.00156765
Echinococcus granulosus Tubulin beta 2C chain 0.0237345 0.0693438 0.0688779
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Echinococcus multilocularis 0.0155132 0.0428347 0.0423554
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Schistosoma mansoni camp-dependent protein kinase type II regulatory subunit 0.00368632 0.00469944 0.00464452
Echinococcus multilocularis somatostatin receptor 0.0350178 0.105726 0.105279
Trichomonas vaginalis guanylate cyclase, putative 0.00266606 0.00140966 0.00156765
Trichomonas vaginalis Clan SC, family S28, unassigned serine peptidase 0.0339089 0.10215 0.175261
Trichomonas vaginalis tubulin gamma chain, putative 0.0237345 0.0693438 0.118697
Giardia lamblia Cathepsin B precursor 0.0426756 0.130418 0.266528
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.153556 0.487948 0.487919
Entamoeba histolytica PH domain containing protein kinase, putative 0.00327259 0.00336539 0.00579746
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0426756 0.130418 0.223999
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Brugia malayi Sex muscle abnormal protein 5 0.00280603 0.001861 0.00180593
Echinococcus multilocularis tyrosine protein kinase Fyn 0.00719882 0.0160253 0.0155327
Brugia malayi hypothetical protein 0.0350178 0.105726 0.105677
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0101101 0.0254124 0.0437773
Leishmania major beta tubulin 0.0237345 0.0693438 0.113312
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0297584 0.0887674 0.0887172
Loa Loa (eye worm) AGC/PKG protein kinase 0.00484401 0.00843236 0.0079359
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0350178 0.105726 0.105677
Trichomonas vaginalis conserved hypothetical protein 0.0062898 0.0130942 0.0217137
Brugia malayi Cyclin, N-terminal domain containing protein 0.0491228 0.151207 0.15116
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0350178 0.105726 0.105279
Echinococcus multilocularis neuropeptide Y receptor 0.0350178 0.105726 0.105279
Giardia lamblia Cysteine protease 0.0426756 0.130418 0.266528
Echinococcus multilocularis g protein coupled receptor 0.0350178 0.105726 0.105279
Schistosoma mansoni serine/threonine protein kinase 0.00822065 0.0193202 0.0192661
Onchocerca volvulus 0.0062898 0.0130942 0.0217422
Echinococcus multilocularis rhodopsin orphan GPCR 0.0350178 0.105726 0.105279
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.00706599 0.015597 0.0151042
Schistosoma mansoni hypothetical protein 0.00618448 0.0127546 0.0127002
Brugia malayi Calcitonin receptor-like protein seb-1 0.00279123 0.00181326 0.00175818
Entamoeba histolytica cysteine protease, putative 0.099263 0.312881 0.538992
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.00430629 0.00669849 0.0106864
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.00903343 0.0219409 0.0214512
Echinococcus multilocularis integrin alpha ps 0.00612794 0.0125723 0.0120779
Brugia malayi Carboxylesterase family protein 0.0679658 0.211965 0.211922
Echinococcus multilocularis cAMP dependent protein kinase type II regulatory 0.00368632 0.00469944 0.00420111
Loa Loa (eye worm) hypothetical protein 0.0350178 0.105726 0.105279
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.00269638 0.00150744 0.00145234

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) = 2.061 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Inhibitors of DnaB-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] ChEMBL. No reference
AC50 (functional) = 21.02 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Secondary Screen to Identify Non-Covalent Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2223, AID489010, AID492950] ChEMBL. No reference
Activity (functional) NOVARTIS: Antimalarial liver stage activity measured as a greater than 50% reduction in Plasmodium yoelii schizont area in HepG2-A16-CD81 cells at 10uM compound concentration, determined by immuno-fluorescence. ChEMBL. 22096101
CC50 (functional) = 22.18 uM Huh7 cytotoxicity for Pf inhibitors Novartis-GNF Malaria Box. No reference
CC50 = 22.18 uM NOVARTIS: Cytotoxicity against human hepatocellular carcinoma cell line (Huh7) ChEMBL. 18579783
EC50 (functional) = 0.1027 uM W2 Pf proliferation inhibition Novartis-GNF Malaria Box. No reference
EC50 (functional) = 0.1027 uM NOVARTIS: Inhibition of Plasmodium falciparum W2 (drug-resistant) proliferation in erythrocyte-based infection assay ChEMBL. 18579783
EC50 (functional) = 0.2007 uM PF proliferation inhibition 3D7 Novartis-GNF Malaria Box. No reference
EC50 (functional) = 0.2007 uM NOVARTIS: Inhibition of Plasmodium falciparum 3D7 (drug-susceptible) proliferation in erythrocyte-based infection assay ChEMBL. 18579783
EC50 (functional) = 0.645 uM PUBCHEM_BIOASSAY: Fluorescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of RecA-Intein Splicing Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2097, AID2223, AID489010, AID492950] ChEMBL. No reference
IC50 (functional) 155.089 uM PubChem BioAssay. Absorbance-based biochemical high throughput dose response assay to identify inhibitors of Methionine sulfoxide reductase A (MsrA). (Class of assay: confirmatory) ChEMBL. No reference
IFI promiscuity index = 0.07692 IFI promiscuity index Novartis-GNF Malaria Box. No reference
Potency (functional) = 0.1259 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.2936 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 0.4147 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 0.5 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 2.0546 uM PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] ChEMBL. No reference
Potency (functional) 2.0596 uM PubChem BioAssay. qHTS for Inhibitors of TGF-b: Confirmation of Cherry Picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.5119 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.8184 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 3.6898 uM PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] ChEMBL. No reference
Potency (functional) 4.4668 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (binding) 5.0119 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.8048 uM PubChem BioAssay. qHTS for Inhibitors of TGF-b: Hit Validation in HepG2 Cells using COP promoter. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3078 uM PubChem BioAssay. qHTS for Inhibitors of TGF-b: CCL64 Cells Orthogonal Assay for Cherry Picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.9433 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.2 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.2 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS for Agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.5821 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 29.0929 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 79.4328 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 18579783
Homo sapiens ChEMBL23
Giardia lamblia

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.