Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
233 records found | Showing page 1 of 10 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv1916 | OG5_129572 | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg |
M. tuberculosis | Rv1862 | OG5_126661 | Probable alcohol dehydrogenase AdhA |
M. tuberculosis | Rv2428 | OG5_126593 | Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C) |
M. tuberculosis | Rv2429 | OG5_165107 | Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D) |
M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) |
M. tuberculosis | Rv0768 | OG5_127004 | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+ ... |
M. tuberculosis | Rv0711 | OG5_126989 | Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) |
M. tuberculosis | Rv1876 | OG5_135716 | Probable bacterioferritin BfrA |
M. tuberculosis | Rv3841 | OG5_127547 | Bacterioferritin BfrB |
M. tuberculosis | Rv2641 | OG5_178694 | Cadmium inducible protein CadI |
M. tuberculosis | Rv2066 | OG5_135738 | Probable bifunctional protein, CobI-COBJ fusion protein: S-adenosyl-L-methionine ... |
M. tuberculosis | Rv3484 | OG5_213861 | Possible conserved protein CpsA |
M. tuberculosis | Rv0806c | OG5_135833 | Possible UDP-glucose-4-epimerase CpsY (galactowaldenase) (UDP-galactose-4-epimer ... |
M. tuberculosis | Rv2266 | OG5_132455 | Probable cytochrome P450 124 Cyp124 |
M. tuberculosis | Rv3518c | OG5_132455 | Probable cytochrome P450 monooxygenase 142 Cyp142 |
M. tuberculosis | Rv0764c | OG5_129288 | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lano ... |
M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD |
M. tuberculosis | Rv1286 | OG5_168022 | Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + ... |
M. tuberculosis | Rv3132c | OG5_153508 | Two component sensor histidine kinase DevS |
M. tuberculosis | Rv2364c | OG5_127948 | Probable GTP-binding protein Era |
M. tuberculosis | Rv3874 | OG5_178673 | 10 kDa culture filtrate antigen EsxB (LHP) (CFP10) |
M. tuberculosis | Rv0859 | OG5_159023 | Possible acyl-CoA thiolase FadA |
M. tuberculosis | Rv3556c | OG5_147360 | Probable acetyl-CoA acetyltransferase FadA6 (acetoacetyl-CoA thiolase) |
M. tuberculosis | Rv1750c | OG5_239145 | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA ... |