Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
233 records found | Showing page 10 of 10 (records 226-233) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv3866 | No group | ESX-1 secretion-associated protein EspG1 |
M. tuberculosis | Rv3876 | OG5_152910 | ESX-1 secretion-associated protein EspI. Conserved proline and alanine rich prot ... |
M. tuberculosis | Rv2710 | OG5_237645 | RNA polymerase sigma factor SigB |
M. tuberculosis | Rv1221 | OG5_132054 | Alternative RNA polymerase sigma factor SigE |
M. tuberculosis | Rv2623 | OG5_126997 | Universal stress protein family protein TB31.7 |
M. tuberculosis | Rv1174c | No group | Low molecular weight T-cell antigen TB8.4 |
M. tuberculosis | Rv3914 | OG5_126613 | Thioredoxin TrxC (TRX) (MPT46) |
M. tuberculosis | Rv3416 | OG5_237579 | Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster. |