Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
233 records found | Showing page 9 of 10 (records 201-225) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
M. tuberculosis | Rv3130c | OG5_133846 | Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1 |
M. tuberculosis | Rv3131 | OG5_179425 | Conserved protein |
M. tuberculosis | Rv3134c | OG5_126997 | Universal stress protein family protein |
M. tuberculosis | Rv3173c | OG5_171043 | Probable transcriptional regulatory protein (probably TetR/AcrR-family) |
M. tuberculosis | Rv3269 | OG5_237606 | Conserved protein |
M. tuberculosis | Rv3334 | OG5_132018 | Probable transcriptional regulatory protein (probably MerR-family) |
M. tuberculosis | Rv3371 | OG5_133846 | Possible triacylglycerol synthase (diacylglycerol acyltransferase) |
M. tuberculosis | Rv3380c | OG5_128670 | Probable transposase |
M. tuberculosis | Rv3406 | OG5_129515 | Probable dioxygenase |
M. tuberculosis | Rv3427c | OG5_146634 | Possible transposase |
M. tuberculosis | Rv3437 | No group | Possible conserved transmembrane protein |
M. tuberculosis | Rv3467 | OG5_151920 | Conserved hypothetical protein |
M. tuberculosis | Rv3482c | No group | Probable conserved membrane protein |
M. tuberculosis | Rv3538 | OG5_129142 | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. |
M. tuberculosis | Rv3572 | No group | Unknown protein |
M. tuberculosis | Rv3613c | No group | Hypothetical protein |
M. tuberculosis | Rv3615c | OG5_237582 | ESX-1 secretion-associated protein EspC |
M. tuberculosis | Rv3616c | OG5_237581 | ESX-1 secretion-associated protein A, EspA |
M. tuberculosis | Rv3639c | No group | Conserved hypothetical protein |
M. tuberculosis | Rv3741c | No group | Possible oxidoreductase |
M. tuberculosis | Rv3776 | OG5_166864 | Conserved hypothetical protein |
M. tuberculosis | Rv3830c | No group | Transcriptional regulatory protein (probably TetR-family) |
M. tuberculosis | Rv3832c | OG5_146620 | Conserved protein |
M. tuberculosis | Rv3833 | OG5_136239 | Transcriptional regulatory protein (probably AraC-family) |
M. tuberculosis | Rv3847 | OG5_237545 | Hypothetical protein |