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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv0885 | OG5_237762 | Conserved hypothetical protein | 762 |
M. tuberculosis | Rv3290c | OG5_129508 | Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysi ... | 752 |
M. tuberculosis | Rv2004c | OG5_142650 | Conserved protein | 717 |
M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) | 714 |
M. tuberculosis | Rv2628 | No group | Hypothetical protein | 679 |
M. tuberculosis | Rv2626c | OG5_130004 | Hypoxic response protein 1 Hrp1 | 657 |
M. tuberculosis | Rv2623 | OG5_126997 | Universal stress protein family protein TB31.7 | 657 |
M. tuberculosis | Rv3340 | OG5_130839 | Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetyl ... | 631 |
M. tuberculosis | Rv2497c | OG5_128261 | Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA | 615 |
M. tuberculosis | Rv2629 | No group | Conserved protein | 613 |
M. tuberculosis | Rv2627c | OG5_239110 | Conserved protein | 610 |
M. tuberculosis | Rv3130c | OG5_133846 | Triacylglycerol synthase (diacylglycerol acyltransferase) Tgs1 | 605 |
M. tuberculosis | Rv2035 | No group | Conserved hypothetical protein | 602 |
M. tuberculosis | Rv2624c | OG5_126997 | Universal stress protein family protein | 601 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 596 |
M. tuberculosis | Rv1813c | OG5_239134 | Conserved hypothetical protein | 594 |
M. tuberculosis | Rv3131 | OG5_179425 | Conserved protein | 591 |
M. tuberculosis | Rv2630 | No group | Hypothetical protein | 580 |
M. tuberculosis | Rv0251c | OG5_126935 | Heat shock protein Hsp (heat-stress-induced ribosome-binding protein A) | 579 |
M. tuberculosis | Rv1285 | OG5_137554 | Probable sulfate adenylyltransferase subunit 2 CysD | 576 |
M. tuberculosis | Rv2830c | No group | Possible antitoxin VapB22 | 569 |
M. tuberculosis | Rv0275c | OG5_179227 | Possible transcriptional regulatory protein (possibly TetR-family) | 566 |
M. tuberculosis | Rv2711 | OG5_132027 | Iron-dependent repressor and activator IdeR | 565 |
M. tuberculosis | Rv3126c | No group | Hypothetical protein | 556 |
M. tuberculosis | Rv3287c | No group | Anti-sigma factor RsbW (sigma negative effector) | 549 |