Target list

Search results for query: PLoS NTD Query 7 (P. falciparum apicoplast)

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  • Score for genes in query #245 (Pfa NOT in humans): 50
  • Score for genes in query #235 (Pfa Enzymes (EC + functional category)): 100
  • Score for genes in query #241 (Pfa compound desirability >0.2): 10
  • Score for genes in query #249 (Pfa assayable): 20
  • Score for genes in query #247 (Pfa any genetic validation): -50
  • Score for genes in query #242 (Pfa Pubmed): -20
  • Score for genes in query #236 (Pfa any essentiality): 50
  • Score for genes in query #244 (Pfa Modbase structure models): 10
  • Score for genes in query #238 (Pfa expression in any RBC stage (80-100%)): 25
  • Score for genes in query #251 (Curated list of nuclear encode apicoplast targeted gene from Stuart Ralph): 1000
  • Score for genes in query #248 (Pfa Dindex >=0.4): 20
  • Score for genes in query #240 (Pfa uploaded weighted list for molecular weight): 0
  • Score for genes in query #243 (Pfa PDB structures): -100
  • Score for genes in query #239 (Pfa uploaded weighted list for Isoelectric point): 0
  • Score for genes in query #246 (Pfa ortholog in taxon (Pvi)): 50
  • Score for genes in query #237 (Pfa all proteins): 1

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

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4804 records found | Showing page 192 of 193 (records 4776-4800) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1031000   OG5_156053   25 kDa ookinete surface antigen precursor 11
P. falciparum   PF3D7_1126100   OG5_128264   autophagy-related protein 7, putative 11
P. falciparum   PF3D7_1302200   OG5_167441   early transcribed membrane protein 13 11
P. falciparum   PF3D7_1335900   OG5_144162   thrombospondin-related anonymous protein 11
P. falciparum   PF3D7_1462000   OG5_134420   thioredoxin-like protein 11
P. falciparum   PF3D7_0612900   OG5_127411   nucleolar GTP-binding protein 1, putative 11
P. falciparum   PF3D7_1245100   OG5_127200   kinesin-13, putative 11
P. falciparum   PF3D7_1249500   OG5_128186   cutA, putative 11
P. falciparum   PF3D7_0715100   OG5_129799   C-Myc-binding protein, putative 1
P. falciparum   PF3D7_1470000   OG5_130185   autophagy-related protein 12, putative 1
P. falciparum   PF3D7_0213400   OG5_145294   protein kinase 7 -9
P. falciparum   PF3D7_1351100   OG5_128549   conserved protein, unknown function -14
P. falciparum   PF3D7_0802200   OG5_126593   1-cys peroxiredoxin -14
P. falciparum   PF3D7_1033900   OG5_128230   ubiquitin-conjugating enzyme E2, putative -14
P. falciparum   PF3D7_1035400   OG5_173153   merozoite surface protein 3 -14
P. falciparum   PF3D7_1132800   OG5_126615   aquaglyceroporin -14
P. falciparum   PF3D7_1144900   OG5_127256   ras-related protein Rab-6 -14
P. falciparum   PF3D7_1302100     No group gamete antigen 27/25 -14
P. falciparum   PF3D7_1477800   OG5_127366   acyl-CoA binding protein -14
P. falciparum   PF3D7_0206800   OG5_160444   merozoite surface protein 2 -14
P. falciparum   PF3D7_0305700   OG5_127771   ubiquitin-conjugating enzyme E2, putative -14
P. falciparum   PF3D7_0207600   OG5_132467   serine repeat antigen 5 -34
P. falciparum   PF3D7_1406700   OG5_127553   vacuolar protein sorting-associated protein 29 -39
P. falciparum   PF3D7_1457200   OG5_126613   thioredoxin 1 -39
P. falciparum   PF3D7_1200600   OG5_128193   erythrocyte membrane protein 1, PfEMP1 -39

Showing page 192 (records 4776-4800) of 193