TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 420.374 | Formula: C18H13N4NaO5S
H donors: 3 H acceptors: 6 LogP: 3.21 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: [O-]C(=O)c1cc(/N=N/c2ccc(cc2)S(=O)(=O)Nc2ccccn2)ccc1O.[Na+]
InChi: 1S/C18H14N4O5S.Na/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17;/h1-11,23H,(H,19,22)(H,24,25);/q;+1/p-1/b21-20+;
InChiKey: RDHFCNKNCNJWHC-ANVLNOONSA-M

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Echinococcus multilocularis	caspase	0.0464	0.139	0.139
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.2206	0.9148	0.9148
Brugia malayi	calpain family protein 1	0.2206	0.9148	0.9148
Onchocerca volvulus		0.0672	0.2315	0.4254
Plasmodium falciparum	metacaspase 1	0.0175	0.0101	0.0291
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Trypanosoma cruzi	conserved protein	0.025	0.0437	0.0437
Trypanosoma brucei	calpain-like protein, putative	0.0832	0.3029	0.9512
Trypanosoma brucei	kinesin, putative	0.0582	0.1915	0.6014
Brugia malayi	fibroinase precursor	0.0182	0.0133	0.0133
Loa Loa (eye worm)	proteasome A-type and B-type family protein	0.016	0.0034	0.0034
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0672	0.2315	1
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Plasmodium falciparum	serine repeat antigen 9	0.0182	0.0133	0.0434
Trichomonas vaginalis	hypothetical protein	0.025	0.0437	0.1373
Entamoeba histolytica	cysteine proteinase, putative	0.0469	0.1411	0.6094
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Brugia malayi	calpain 7	0.0832	0.3029	0.3029
Schistosoma mansoni	cathepsin F (C01 family)	0.0469	0.1411	0.1411
Brugia malayi	Papain family cysteine protease containing protein	0.0182	0.0133	0.0133
Leishmania major	hypothetical protein, unknown function	0.025	0.0437	0.1373
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0182	0.0133	0.0439
Trichomonas vaginalis	set domain proteins, putative	0.0229	0.0345	0.1083
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Loa Loa (eye worm)	hypothetical protein	0.0203	0.0227	0.0227
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.9512
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0867	0.3185	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0672	0.2315	0.2315
Schistosoma mansoni	calpain (C02 family)	0.0832	0.3029	0.3029
Onchocerca volvulus	Cathepsin L homolog	0.0672	0.2315	0.4254
Toxoplasma gondii	hypothetical protein	0.025	0.0437	0.1373
Trypanosoma cruzi	cysteine peptidase, putative	0.0203	0.0227	0.0227
Mycobacterium tuberculosis	Proteasome beta subunit PrcB; assembles with alpha subunit PrcA.	0.016	0.0034	0.5
Giardia lamblia	Cysteine protease	0.0182	0.0133	0.0418
Loa Loa (eye worm)	hypothetical protein	0.025	0.0437	0.0437
Loa Loa (eye worm)	hypothetical protein	0.1374	0.5442	0.5442
Leishmania major	metacaspase, putative	0.0175	0.0101	0.0316
Leishmania major	cathepsin L-like protease	0.0725	0.2553	0.8018
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Echinococcus multilocularis	family C2 unassigned peptidase (C02 family)	0.2354	0.9809	0.9809
Giardia lamblia	Cathepsin B precursor	0.0182	0.0133	0.0418
Loa Loa (eye worm)	calpain	0.0832	0.3029	0.3029
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Brugia malayi	mucosa associated lymphoid tissue lymphoma translocation protein 1	0.0175	0.0101	0.0101
Echinococcus multilocularis	cathepsin L	0.0182	0.0133	0.0133
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0385	0.1037	0.4398
Trypanosoma brucei	metacaspase MCA2	0.0175	0.0101	0.0316
Trypanosoma brucei	Metacaspase-4	0.0175	0.0101	0.0316
Trypanosoma cruzi	cruzipain precursor, putative	0.0725	0.2553	0.2553
Giardia lamblia	Cathepsin B precursor	0.0182	0.0133	0.0418
Trypanosoma cruzi	kinesin, putative	0.0582	0.1915	0.1915
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0385	0.1037	0.3257
Onchocerca volvulus	Cell death protein 3 homolog	0.0335	0.0815	0.1498
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.0832	0.3029	0.3029
Trypanosoma cruzi	cruzipain precursor, putative	0.0203	0.0227	0.0227
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0182	0.0133	0.0418
Echinococcus multilocularis	cathepsin L cysteine protease	0.0672	0.2315	0.2315
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Onchocerca volvulus		0.0469	0.1411	0.2592
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.3029
Leishmania major	kinesin, putative	0.0582	0.1915	0.6014
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0672	0.2315	0.2315
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0182	0.0133	0.0418
Giardia lamblia	Cysteine protease	0.0182	0.0133	0.0418
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0182	0.0133	0.0439
Echinococcus multilocularis	apoptotic protease activating factor 1	0.016	0.0038	0.0038
Leishmania major	calpain, putative,cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.9512
Onchocerca volvulus		0.023	0.0346	0.0636
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Loa Loa (eye worm)	calpain D	0.025	0.0437	0.0437
Schistosoma mansoni	proteasome catalytic subunit 3 (T01 family)	0.016	0.0034	0.0034
Trypanosoma brucei	calpain-like protein, putative	0.0832	0.3029	0.9512
Entamoeba histolytica	cysteine protease, putative	0.0672	0.2315	1
Trypanosoma brucei	Calpain-like protein 2	0.025	0.0437	0.1373
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0182	0.0133	0.0418
Echinococcus multilocularis	calpain 7 (C02 family)	0.0832	0.3029	0.3029
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0182	0.0133	0.0439
Schistosoma mansoni	cathepsin F (C01 family)	0.0672	0.2315	0.2315
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0867	0.3185	0.3185
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0182	0.0133	0.0418
Leishmania major	cysteine peptidase A (CPA)	0.0672	0.2315	0.7269
Trypanosoma cruzi	cysteine peptidase, putative	0.0672	0.2315	0.2315
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0182	0.0133	0.0418
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0182	0.0133	0.0418
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Trypanosoma cruzi	metacaspase, putative	0.0175	0.0101	0.0101
Trypanosoma brucei	metacaspase 5, putative	0.0175	0.0101	0.0316
Brugia malayi	calpain 5	0.0582	0.1915	0.1915
Trypanosoma brucei	metacaspase	0.0175	0.0101	0.0316
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.2397	1	1
Brugia malayi	cathepsin L precursor	0.0182	0.0133	0.0133
Toxoplasma gondii	cathepsin CPC2	0.0182	0.0133	0.0418
Trichomonas vaginalis	conserved hypothetical protein	0.025	0.0437	0.1373
Schistosoma mansoni	caspase-7 (C14 family)	0.0335	0.0815	0.0815
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0182	0.0133	0.0575
Trichomonas vaginalis	Family T1, proteasome beta subunit, threonine peptidase	0.016	0.0034	0.0107
Plasmodium vivax	proteasome subunit beta type-5, putative	0.016	0.0034	0.0113
Trypanosoma brucei	antigen, putative	0.0832	0.3029	0.9512
Trypanosoma brucei	Calpain-like protein CALP1.3	0.025	0.0437	0.1373
Entamoeba histolytica	calpain family cysteine protease, putative	0.025	0.0437	0.1889
Onchocerca volvulus		0.0672	0.2315	0.4254
Entamoeba histolytica	hypothetical protein	0.0182	0.0133	0.0575
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Plasmodium vivax	serine-repeat antigen (SERA)	0.0182	0.0133	0.0439
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0182	0.0133	0.0418
Entamoeba histolytica	calpain large subunit domain III containing protein	0.0582	0.1915	0.8273
Brugia malayi	calpain D	0.025	0.0437	0.0437
Schistosoma mansoni	caspase-7 (C14 family)	0.0464	0.139	0.139
Brugia malayi	Cathepsin L-like precursor	0.0469	0.1411	0.1411
Trypanosoma cruzi	cysteine proteinase, putative	0.0385	0.1037	0.1037
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0175	0.0101	0.0316
Schistosoma mansoni	cathepsin B (C01 family)	0.0182	0.0133	0.0133
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0182	0.0133	0.0133
Brugia malayi	calpain family protein 1	0.2206	0.9148	0.9148
Trichomonas vaginalis	conserved hypothetical protein	0.0182	0.0133	0.0418
Plasmodium vivax	metacaspase 1, putative	0.0175	0.0101	0.0332
Echinococcus granulosus	caspase 2	0.0335	0.0815	0.0815
Onchocerca volvulus		0.0672	0.2315	0.4254
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Onchocerca volvulus	Cathepsin L homolog	0.0182	0.0133	0.0245
Echinococcus granulosus	calpain A	0.2358	0.9825	0.9825
Onchocerca volvulus		0.016	0.0038	0.007
Echinococcus granulosus	calpain 7 C02 family	0.0832	0.3029	0.3029
Giardia lamblia	Cathepsin B precursor	0.0867	0.3185	1
Plasmodium falciparum	serine repeat antigen 2	0.0182	0.0133	0.0434
Giardia lamblia	Cathepsin B precursor	0.0182	0.0133	0.0418
Giardia lamblia	Cathepsin B precursor	0.0182	0.0133	0.0418
Leishmania major	proteasome beta 5 subunit, putative	0.016	0.0034	0.0107
Leishmania major	hypothetical protein, conserved	0.025	0.0437	0.1373
Echinococcus multilocularis	cysteine protease	0.0672	0.2315	0.2315
Schistosoma mansoni	subfamily C14A unassigned peptidase (C14 family)	0.0175	0.0101	0.0101
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0385	0.1037	0.1037
Loa Loa (eye worm)	hypothetical protein	0.2397	1	1
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Trypanosoma brucei	calpain, putative	0.025	0.0437	0.1373
Brugia malayi	Papain family cysteine protease containing protein	0.0182	0.0133	0.0133
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0867	0.3185	1
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0202	0.0221	0.0221
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0175	0.0101	0.0316
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0182	0.0133	0.0434
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Schistosoma mansoni	hypothetical protein	0.016	0.0038	0.0038
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.2397	1	1
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Toxoplasma gondii	cathepsin CPL	0.0672	0.2315	0.7269
Entamoeba histolytica	protein kinase, putative	0.0582	0.1915	0.8273
Plasmodium vivax	unspecified product	0.0385	0.1037	0.3425
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0182	0.0133	0.0133
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Echinococcus multilocularis	cathepsin b	0.2397	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0725	0.2553	0.2553
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trichomonas vaginalis	conserved hypothetical protein	0.0182	0.0133	0.0418
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Giardia lamblia	Cathepsin L-like protease	0.0182	0.0133	0.0418
Loa Loa (eye worm)	hypothetical protein	0.0203	0.0227	0.0227
Trypanosoma brucei	hypothetical protein	0.025	0.0437	0.1373
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Trypanosoma cruzi	cysteine peptidase, putative	0.0725	0.2553	0.2553
Schistosoma mansoni	caspase-3 (C14 family)	0.0464	0.139	0.139
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Loa Loa (eye worm)	hypothetical protein	0.0469	0.1411	0.1411
Brugia malayi	Cathepsin L-like precursor	0.0469	0.1411	0.1411
Schistosoma mansoni	cathepsin F (C01 family)	0.0672	0.2315	0.2315
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0182	0.0133	0.0418
Echinococcus granulosus	cathepsin L	0.0385	0.1037	0.1037
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.025	0.0437	0.1373
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0182	0.0133	0.0434
Trypanosoma cruzi	major cysteine proteinase, putative	0.0182	0.0133	0.0133
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Toxoplasma gondii	cathepsin CPC1	0.0182	0.0133	0.0418
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0182	0.0133	0.0133
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0182	0.0133	0.0133
Brugia malayi	cathepsin L-like precursor	0.0469	0.1411	0.1411
Loa Loa (eye worm)	cysteine protease	0.0672	0.2315	0.2315
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Brugia malayi	calpain 5	0.025	0.0437	0.0437
Brugia malayi	Papain family cysteine protease containing protein	0.0672	0.2315	0.2315
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Leishmania major	calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Plasmodium vivax	serine-repeat antigen (SERA)	0.0182	0.0133	0.0439
Trypanosoma cruzi	calpain cysteine peptidase, putative	0.025	0.0437	0.0437
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0182	0.0133	0.0133
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0182	0.0133	0.0418
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0867	0.3185	0.3185
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0182	0.0133	0.0434
Plasmodium falciparum	metacaspase-like protein	0.0175	0.0101	0.0291
Toxoplasma gondii	ICE family protease (caspase) p20 domain-containing protein	0.0175	0.0101	0.0316
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0385	0.1037	0.3257
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0672	0.2315	0.2315
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Mycobacterium ulcerans	proteasome PrcB	0.016	0.0034	0.5
Echinococcus granulosus	cathepsin b	0.2397	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0182	0.0133	0.0418
Echinococcus granulosus	cysteine protease	0.0385	0.1037	0.1037
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0182	0.0133	0.0133
Echinococcus granulosus	calpain 5	0.0832	0.3029	0.3029
Mycobacterium leprae	proteasome (beta subunit) PrcB	0.016	0.0034	0.5
Trypanosoma brucei	metacaspase MCA3	0.0175	0.0101	0.0316
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0867	0.3185	1
Echinococcus granulosus	cathepsin l1	0.0672	0.2315	0.2315
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2397	1	1
Brugia malayi	Papain family cysteine protease containing protein	0.0385	0.1037	0.1037
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.3029
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.025	0.0437	0.0437
Brugia malayi	hypothetical protein	0.016	0.0038	0.0038
Giardia lamblia	Cathepsin B precursor	0.0867	0.3185	1
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Leishmania major	cathepsin L-like protease	0.0672	0.2315	0.7269
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0182	0.0133	0.0439
Trichomonas vaginalis	calpain, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Trypanosoma brucei	calpain-like protein, putative	0.0832	0.3029	0.9512
Schistosoma mansoni	cathepsin C	0.0182	0.0133	0.0133
Loa Loa (eye worm)	calpain 5	0.0582	0.1915	0.1915
Schistosoma mansoni	calpain-7 (C02 family)	0.0832	0.3029	0.3029
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0182	0.0133	0.0439
Giardia lamblia	Cathepsin B precursor	0.0867	0.3185	1
Onchocerca volvulus	Cathepsin F homolog	0.0672	0.2315	0.4254
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Entamoeba histolytica	cysteine proteinase 1, putative	0.0385	0.1037	0.4481
Echinococcus multilocularis	calpain A	0.2358	0.9825	0.9825
Plasmodium vivax	hypothetical protein, conserved	0.0175	0.0101	0.0332
Plasmodium vivax	unspecified product	0.0182	0.0133	0.0439
Echinococcus granulosus	cathepsin l1	0.0469	0.1411	0.1411
Entamoeba histolytica	cysteine proteinase, putative	0.0385	0.1037	0.4481
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Giardia lamblia	Cysteine protease	0.0182	0.0133	0.0418
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0182	0.0133	0.0133
Giardia lamblia	Hypothetical protein	0.0182	0.0133	0.0418
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0672	0.2315	1
Schistosoma mansoni	calpain-7 (C02 family)	0.0832	0.3029	0.3029
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.3029
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.3029
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Echinococcus multilocularis	cathepsin L	0.0385	0.1037	0.1037
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0182	0.0133	0.0133
Leishmania major	cathepsin L-like protease	0.0672	0.2315	0.7269
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Echinococcus multilocularis	caspase 8	0.0175	0.0101	0.0101
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Trypanosoma cruzi	cysteine protease, putative	0.0385	0.1037	0.1037
Onchocerca volvulus		0.0672	0.2315	0.4254
Schistosoma mansoni	cathepsin s	0.0203	0.0227	0.0227
Trypanosoma cruzi	major cysteine proteinase, putative	0.0235	0.0372	0.0372
Giardia lamblia	Encystation-specific protease	0.0182	0.0133	0.0418
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Loa Loa (eye worm)	hypothetical protein	0.0203	0.0227	0.0227
Loa Loa (eye worm)	hypothetical protein	0.0175	0.0101	0.0101
Brugia malayi	cathepsin L-like cysteine proteinase	0.0182	0.0133	0.0133
Schistosoma mansoni	cathepsin S (C01 family)	0.0182	0.0133	0.0133
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0203	0.0227	0.0227
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Giardia lamblia	Cathepsin B precursor	0.0182	0.0133	0.0418
Giardia lamblia	Proteasome subunit beta type 5 precursor	0.016	0.0034	0.0107
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.9512
Toxoplasma gondii	cathepsin B	0.0867	0.3185	1
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0203	0.0227	0.0227
Entamoeba histolytica	cysteine proteinase, putative	0.0672	0.2315	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0182	0.0133	0.0418
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0672	0.2315	0.2315
Plasmodium falciparum	serine repeat antigen 3	0.0182	0.0133	0.0434
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2397	1	1
Echinococcus granulosus	caspase 3 apoptosis cysteine peptidase	0.0464	0.139	0.139
Plasmodium falciparum	serine repeat antigen 8	0.0182	0.0133	0.0434
Echinococcus granulosus	proteasome prosome macropain	0.016	0.0034	0.0034
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Echinococcus multilocularis	calpain	0.0832	0.3029	0.3029
Brugia malayi	Pre-SET motif family protein	0.0202	0.0221	0.0221
Brugia malayi	Cathepsin L-like precursor	0.0672	0.2315	0.2315
Entamoeba histolytica	cysteine proteinase 2	0.0385	0.1037	0.4481
Giardia lamblia	Dipeptidyl-peptidase I precursor	0.0182	0.0133	0.0418
Echinococcus multilocularis	calpain family protein 1, d	0.1624	0.6556	0.6556
Trypanosoma brucei	cytoskeleton-associated protein CAP5.5, putative	0.025	0.0437	0.1373
Leishmania major	cathepsin L-like protease	0.0672	0.2315	0.7269
Trypanosoma cruzi	cysteine peptidase, putative	0.0385	0.1037	0.1037
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.2354	0.9809	0.9809
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0385	0.1037	0.3257
Brugia malayi	Proteasome A-type and B-type family protein	0.016	0.0034	0.0034
Echinococcus granulosus	caspase	0.0464	0.139	0.139
Echinococcus multilocularis	survival motor neuron protein 1	0.0229	0.0343	0.0343
Toxoplasma gondii	proteasome subunit beta type, putative	0.016	0.0034	0.0107
Echinococcus granulosus	calpain	0.0832	0.3029	0.3029
Leishmania major	calpain protease-like protein	0.025	0.0437	0.1373
Echinococcus multilocularis	caspase 3, apoptosis cysteine peptidase	0.0464	0.139	0.139
Loa Loa (eye worm)	hypothetical protein	0.2206	0.9148	0.9148
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.025	0.0437	0.0437
Brugia malayi	Papain family cysteine protease containing protein	0.0182	0.0133	0.0133
Entamoeba histolytica	cysteine proteinase, putative	0.0385	0.1037	0.4481
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Trypanosoma cruzi	cysteine peptidase, putative	0.0725	0.2553	0.2553
Trypanosoma cruzi	metacaspase, putative	0.0175	0.0101	0.0101
Onchocerca volvulus		0.0672	0.2315	0.4254
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0522	0.1649	0.1649
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0672	0.2315	1
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0672	0.2315	0.7269
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.3029
Onchocerca volvulus	Cathepsin L homolog	0.0672	0.2315	0.4254
Giardia lamblia	Hypothetical protein	0.0182	0.0133	0.0418
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Brugia malayi	Cell death protein 3 precursor	0.0335	0.0815	0.0815
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0182	0.0133	0.0133
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Onchocerca volvulus		0.0182	0.0133	0.0245
Echinococcus multilocularis	caspase 2	0.0335	0.0815	0.0815
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Brugia malayi	cathepsin F-like cysteine proteinase	0.0203	0.0227	0.0227
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Trypanosoma brucei	proteasome subunit beta type-5, putative	0.016	0.0034	0.0107
Plasmodium falciparum	serine repeat antigen 1	0.0182	0.0133	0.0434
Plasmodium falciparum	serine repeat antigen 6	0.0182	0.0133	0.0434
Onchocerca volvulus		0.0672	0.2315	0.4254
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Plasmodium vivax	vivapain-3	0.0385	0.1037	0.3425
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0469	0.1411	0.1411
Loa Loa (eye worm)	hypothetical protein	0.1624	0.6556	0.6556
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0182	0.0133	0.0133
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.3029
Loa Loa (eye worm)	calpain family protein 1	0.1624	0.6556	0.6556
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0182	0.0133	0.0418
Echinococcus multilocularis	calpain 5	0.0832	0.3029	0.3029
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0385	0.1037	0.1037
Trypanosoma brucei	cysteine peptidase, putative	0.025	0.0437	0.1373
Entamoeba histolytica	cysteine proteinase, putative	0.0385	0.1037	0.4481
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Echinococcus multilocularis	cathepsin b	0.2397	1	1
Leishmania major	cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Plasmodium vivax	calpain, putative	0.0832	0.3029	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Leishmania major	cathepsin L-like protease	0.0672	0.2315	0.7269
Trypanosoma brucei	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.9512
Onchocerca volvulus		0.1374	0.5442	1
Plasmodium vivax	vivapain-1	0.0385	0.1037	0.3425
Loa Loa (eye worm)	hypothetical protein	0.016	0.0038	0.0038
Loa Loa (eye worm)	hypothetical protein	0.1955	0.8034	0.8034
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0182	0.0133	0.0575
Trypanosoma brucei	Calpain-like protein 1.2	0.025	0.0437	0.1373
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0672	0.2315	0.7269
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Trypanosoma brucei	calpain-like protein, putative	0.0832	0.3029	0.9512
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Trypanosoma cruzi	metacaspase, putative	0.0175	0.0101	0.0101
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.2397	1	1
Trypanosoma brucei	glucosamine 6-phosphate n-acetyltransferase	0.025	0.0437	0.1373
Trypanosoma cruzi	metacaspase 5, putative	0.0175	0.0101	0.0101
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0182	0.0133	0.0418
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.3029
Schistosoma mansoni	calpain-2 (C02 family)	0.025	0.0437	0.0437
Loa Loa (eye worm)	hypothetical protein	0.0335	0.0815	0.0815
Echinococcus multilocularis	hypothetical protein	0.0832	0.3029	0.3029
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Leishmania major	calpain family cysteine protease-like protein	0.025	0.0437	0.1373
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Schistosoma mansoni	calpain C (C02 family)	0.0832	0.3029	0.3029
Toxoplasma gondii	calpain family cysteine protease domain-containing protein	0.025	0.0437	0.1373
Trypanosoma brucei	calpain, putative	0.025	0.0437	0.1373
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Trichomonas vaginalis	calpain, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0182	0.0133	0.0418
Loa Loa (eye worm)	hypothetical protein	0.0469	0.1411	0.1411
Entamoeba histolytica	cysteine protease, putative	0.0182	0.0133	0.0575
Brugia malayi	cathepsin F-like cysteine proteinase	0.0182	0.0133	0.0133
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Entamoeba histolytica	proteasome subunit beta type 5 precursor, putative	0.016	0.0034	0.0148
Echinococcus granulosus	cathepsin L cysteine protease	0.0385	0.1037	0.1037
Plasmodium vivax	vivapain-2	0.0672	0.2315	0.7642
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.0437
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Trypanosoma cruzi	kinesin, putative	0.0582	0.1915	0.1915
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0182	0.0133	0.0439
Plasmodium falciparum	serine repeat antigen 4	0.0182	0.0133	0.0434
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0725	0.2553	0.8018
Brugia malayi	hypothetical protein	0.0229	0.0343	0.0343
Echinococcus granulosus	family C2 unassigned peptidase C02 family	0.2354	0.9809	0.9809
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0182	0.0133	0.0439
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Plasmodium falciparum	serine repeat antigen 5	0.0182	0.0133	0.0434
Schistosoma mansoni	hypothetical protein	0.025	0.0437	0.0437
Loa Loa (eye worm)	hypothetical protein	0.0672	0.2315	0.2315
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Entamoeba histolytica	cysteine proteinase, putative	0.0385	0.1037	0.4481
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Loa Loa (eye worm)	cathepsin B	0.0867	0.3185	0.3185
Echinococcus granulosus	survival motor neuron protein 1	0.0229	0.0343	0.0343
Echinococcus multilocularis	proteasome (prosome, macropain)	0.016	0.0034	0.0034
Brugia malayi	Papain family cysteine protease containing protein	0.0385	0.1037	0.1037
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Plasmodium vivax	vivapain-2	0.0672	0.2315	0.7642
Loa Loa (eye worm)	hypothetical protein	0.0469	0.1411	0.1411
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0385	0.1037	0.1037
Trypanosoma cruzi	metacaspase 5, putative	0.0175	0.0101	0.0101
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0182	0.0133	0.0439
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Trypanosoma brucei	Calpain-like protein 1.1	0.025	0.0437	0.1373
Entamoeba histolytica	cysteine proteinase, putative	0.0672	0.2315	1
Giardia lamblia	Cathepsin L precursor	0.0182	0.0133	0.0418
Trichomonas vaginalis	calpain, putative	0.025	0.0437	0.1373
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.016	0.0034	0.0034
Echinococcus multilocularis	caspase 3	0.0289	0.0613	0.0613
Trichomonas vaginalis	conserved hypothetical protein	0.0175	0.0101	0.0316
Echinococcus multilocularis	cysteine protease	0.0672	0.2315	0.2315
Echinococcus multilocularis	cathepsin L cysteine protease	0.0672	0.2315	0.2315
Giardia lamblia	Cathepsin B-like cysteine proteinase 3 precursor	0.0182	0.0133	0.0418
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0469	0.1411	0.443
Echinococcus granulosus	caspase 3	0.0289	0.0613	0.0613
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.3029
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0182	0.0133	0.0418
Echinococcus granulosus	cathepsin L	0.0182	0.0133	0.0133
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0182	0.0133	0.0133
Trypanosoma brucei	cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0182	0.0133	0.0439
Loa Loa (eye worm)	fibroinase	0.0672	0.2315	0.2315
Plasmodium falciparum	serine repeat antigen 7	0.0182	0.0133	0.0434
Trypanosoma cruzi	cytoskeleton-associated protein CAP5.5, putative	0.025	0.0437	0.0437
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0182	0.0133	0.0133
Trichomonas vaginalis	Clan CA, family C2, calpain-like cysteine peptidase	0.025	0.0437	0.1373
Echinococcus granulosus	calpain A	0.0832	0.3029	0.3029
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0672	0.2315	0.2315
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0182	0.0133	0.0439
Plasmodium vivax	unspecified product	0.0203	0.0227	0.0751
Loa Loa (eye worm)	hypothetical protein	0.0229	0.0343	0.0343
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0385	0.1037	0.1037
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0385	0.1037	0.3257
Schistosoma mansoni	family C2 unassigned peptidase (C02 family)	0.2354	0.9809	0.9809
Trypanosoma cruzi	metacaspase, putative	0.0175	0.0101	0.0101
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.0832	0.3029	0.3029
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0469	0.1411	0.443
Onchocerca volvulus		0.0672	0.2315	0.4254
Leishmania major	cathepsin L-like protease	0.0672	0.2315	0.7269
Loa Loa (eye worm)	ctsf protein	0.0672	0.2315	0.2315
Trichomonas vaginalis	Clan CD, family C14, metacaspase-like cysteine peptidase	0.0175	0.0101	0.0316
Echinococcus granulosus	caspase 8	0.0175	0.0101	0.0101
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0672	0.2315	0.7269
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Loa Loa (eye worm)	calpain family protein 1	0.2206	0.9148	0.9148
Leishmania major	cathepsin L-like protease	0.0725	0.2553	0.8018
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0672	0.2315	0.2315
Brugia malayi	Cathepsin L-like precursor	0.0203	0.0227	0.0227
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Loa Loa (eye worm)	hypothetical protein	0.0182	0.0133	0.0133
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0182	0.0133	0.0133
Echinococcus granulosus	apoptotic protease activating factor 1	0.016	0.0038	0.0038
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0182	0.0133	0.0133
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0182	0.0133	0.0133
Schistosoma mansoni	Mername-AA248 (C02 family)	0.0832	0.3029	0.3029
Trypanosoma cruzi	cysteine proteinase, putative	0.0385	0.1037	0.1037
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.0832	0.3029	0.9512
Trypanosoma cruzi	proteasome subunit beta type-5, putative	0.016	0.0034	0.0034
Leishmania major	calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative	0.025	0.0437	0.1373
Giardia lamblia	Cysteine protease	0.0182	0.0133	0.0418
Trypanosoma cruzi	calpain-like cysteine peptidase, putative	0.025	0.0437	0.0437
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0672	0.2315	0.7269
Entamoeba histolytica	cysteine protease, putative	0.0385	0.1037	0.4481
Echinococcus granulosus	cathepsin b	0.2397	1	1
Giardia lamblia	Cathepsin L-like protease	0.0182	0.0133	0.0418
Leishmania major	cathepsin L-like protease	0.0725	0.2553	0.8018
Plasmodium falciparum	calpain	0.025	0.0437	0.1768

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

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External resources for this compound

ChEMBL: CHEMBL2311115

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1699107