Detailed information for compound 252309

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 404.41 | Formula: C21H24O8
  • H donors: 5 H acceptors: 6 LogP: 1.42 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCC1OC(Oc2ccccc2c2cccc(c2)C(C(=O)O)C)C(C(C1O)O)O
  • InChi: 1S/C21H24O8/c1-11(20(26)27)12-5-4-6-13(9-12)14-7-2-3-8-15(14)28-21-19(25)18(24)17(23)16(10-22)29-21/h2-9,11,16-19,21-25H,10H2,1H3,(H,26,27)
  • InChiKey: XUAXMFACEQLBHB-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0032 0.0148
Brugia malayi DNA-binding protein D-ETS-3 0.001 0.0001 0.0002
Onchocerca volvulus 0.0046 0.0113 0.0277
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.004 0.0093 0.0807
Echinococcus multilocularis RUN 0.0022 0.0037 0.0041
Echinococcus granulosus Smad4 0.0024 0.0044 0.0048
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.0113 0.0123
Schistosoma mansoni loxhd1 0.0022 0.0037 0.0089
Brugia malayi MH1 domain containing protein 0.0013 0.0012 0.0016
Schistosoma mansoni biogenic amine receptor 0.0046 0.0113 0.0269
Leishmania major RNA polymerase I second largest subunit, putative 0.001 0 0.0003
Brugia malayi Cation transporter family protein 0.0776 0.235 0.3176
Mycobacterium tuberculosis Methionyl-tRNA synthetase MetS (MetRS) (methionine--tRNA ligase) 0.0053 0.0134 0.0205
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0776 0.235 0.3176
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0113 0.0269
Schistosoma mansoni Smad4 0.0011 0.0004 0.0009
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0011 0.0005 0.0005
Brugia malayi DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide 0.0013 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0009 0.0009
Brugia malayi Ets-domain containing protein 0.0068 0.018 0.0243
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Onchocerca volvulus 0.0066 0.0175 0.0429
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0776 0.235 0.2606
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0187 0.086
Schistosoma mansoni neuropeptide receptor 0.0046 0.0113 0.0269
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0367 0.1097 0.1483
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0027 0.003
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0021 0.005
Brugia malayi hypothetical protein 0.0367 0.1097 0.1483
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0119 0.0336 0.4389
Brugia malayi hypothetical protein 0.004 0.0093 0.0126
Onchocerca volvulus 0.0776 0.235 0.577
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Echinococcus granulosus ETS domain containing protein Elk 1 0.001 0.0001 0.0001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Echinococcus multilocularis ETS transcription factor Elf 5 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.005 0.0123 0.0189
Plasmodium vivax importin-beta 2, putative 0.003 0.0062 0.0187
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0033 0.0158
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0042 0.0046
Onchocerca volvulus 0.1338 0.4073 1
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0023 0.0034
Onchocerca volvulus 0.0046 0.0113 0.0277
Echinococcus multilocularis ETS transcription factor Elf 1 0.001 0.0001 0.0001
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Loa Loa (eye worm) phosphatidylinositol 3 0.004 0.0093 0.0093
Mycobacterium ulcerans tryptophan-rich sensory protein 0.1338 0.4073 0.6236
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0013 0.0012 0.0013
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0 0.0002
Brugia malayi N-terminal motif family protein 0.0013 0.0011 0.0015
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0005 0.0006
Entamoeba histolytica hypothetical protein 0.004 0.0093 0.0763
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0111 0.0312 0.0312
Mycobacterium leprae PROBABLE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE NADE (NAD(+) SYNTHASE [GLUTAMINE-HYDROLYSING]) 0.0093 0.0256 0.3032
Loa Loa (eye worm) phosphofructokinase 0.0119 0.0336 0.0336
Schistosoma mansoni lamin 0.0111 0.0312 0.0745
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.0113 0.0125
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0776 0.235 0.3176
Brugia malayi tailless protein 0.0011 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0115 0.0128
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Onchocerca volvulus 0.0776 0.235 0.577
Echinococcus multilocularis expressed protein 0.0388 0.1161 0.1287
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Plasmodium vivax GMP synthetase, putative 0.0037 0.0085 0.0258
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0083 0.0083
Brugia malayi orphan nuclear receptor NR2E1 0.0011 0.0005 0.0006
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Brugia malayi beta-lactamase family protein 0.007 0.0187 0.0253
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0383
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0 0.0001
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0336 0.0336
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0111 0.015
Brugia malayi beta-lactamase 0.007 0.0187 0.0253
Toxoplasma gondii DNA-directed RNA polymerase III RPC2 0.0013 0.0012 0.0103
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.002 0.0031 0.0252
Schistosoma mansoni cpg binding protein 0.0033 0.0071 0.0171
Brugia malayi Isocitrate dehydrogenase 0.0018 0.0025 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0033 0.0079
Echinococcus granulosus glycine receptor subunit beta 0.0776 0.235 0.2566
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0083 0.0091
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus granulosus thyroid hormone receptor alpha 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni hypothetical protein 0.0047 0.0115 0.0276
Trypanosoma brucei RNA polymerase I second largest subunit 0.001 0 0.0003
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0187 0.0286
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Onchocerca volvulus 0.0046 0.0113 0.0277
Brugia malayi hypothetical protein 0.0035 0.008 0.0108
Loa Loa (eye worm) DNA-directed RNA polymerase II second largest subunit 0.0013 0.0012 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0042 0.0057
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0017 0.0018
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0066 0.0175 0.0268
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0383
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0015 0.0017 0.0019
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0 0.0002
Loa Loa (eye worm) apoptosis regulator protein 0.0082 0.0223 0.0223
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0336 0.0803
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0113 0.0125
Echinococcus multilocularis potassium voltage gated channel protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.2055 0.6273 0.6273
Echinococcus granulosus expressed protein 0.0388 0.1161 0.1267
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0262
Echinococcus granulosus allatostatin A receptor 0.0046 0.0113 0.0123
Brugia malayi nuclear receptor NHR-67 0.0011 0.0005 0.0006
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0037 0.0041
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0082 0.0223 0.0247
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0077
Echinococcus multilocularis para nitrobenzyl esterase 0.0024 0.0043 0.0048
Loa Loa (eye worm) hypothetical protein 0.0373 0.1116 0.1116
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0032 0.0068 0.0591
Loa Loa (eye worm) ets-domain-containing protein 0.001 0.0001 0.0001
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.004 0.0093 0.0807
Loa Loa (eye worm) hypothetical protein 0.0052 0.0129 0.0129
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0044 0.0049
Onchocerca volvulus 0.0024 0.0043 0.0107
Brugia malayi DIX domain containing protein 0.0018 0.0027 0.0037
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0336 0.1545
Onchocerca volvulus 0.0046 0.0113 0.0277
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.002 0.0031 0.0047
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0262
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0013 0.0011 0.0051
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0091 0.0438
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.0113 0.0125
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0013 0.0114
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0088 0.0097
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.002 0.0031 0.0267
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.0113 0.0125
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0027 0.003
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0015 0.0017 0.0019
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0265 0.0632
Trypanosoma brucei GMP synthase [glutamine-hydrolysing] 0.0037 0.0085 0.0736
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.002 0.0031 0.0047
Brugia malayi Cation transporter family protein 0.0776 0.235 0.3176
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.0113 0.0113
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0011 0.0005 0.0005
Brugia malayi Cyclic-nucleotide gated cation channel 0.0015 0.0017 0.0023
Plasmodium falciparum DNA-directed RNA polymerase subunit beta, putative 0.007 0.0187 0.0896
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0175 0.0236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0068 0.0314
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0051
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0066 0.0175 0.0268
Loa Loa (eye worm) hypothetical protein 0.0066 0.0175 0.0175
Onchocerca volvulus 0.0046 0.0113 0.0277
Giardia lamblia DNA-directed RNA polymerase RPB2 0.0013 0.0012 0.0451
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0091 0.0101
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Schistosoma mansoni lamin 0.0111 0.0312 0.0745
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0033 0.0036
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0011 0.0005 0.0005
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0028 0.0056 0.0134
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0017 0.004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi excitatory GABA receptor EXP-1A 0.0776 0.235 0.3176
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0159 0.038
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0776 0.235 0.5615
Schistosoma mansoni importin beta-1 0.003 0.0062 0.0148
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0113 0.0125
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0082 0.0223 0.0247
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0018 0.0027 0.0127
Loa Loa (eye worm) RNA binding protein 0.0061 0.0159 0.0159
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0776 0.235 0.235
Trypanosoma cruzi RNA polymerase I second largest subunit, putative 0.001 0 0.0003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.002 0.0031 0.0047
Brugia malayi Melatonin receptor type 1A 0.0046 0.0113 0.0152
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.0113 0.0152
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.0113 0.0123
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.0113 0.0269
Mycobacterium ulcerans hypothetical protein 0.007 0.0187 0.0286
Trypanosoma cruzi NAD+ synthase, putative 0.0093 0.0256 0.2217
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0035
Echinococcus multilocularis neuropeptide s receptor 0.0948 0.2878 0.3192
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0032 0.0036
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0005 0.0011
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.001 0.0001 0.0001
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Onchocerca volvulus 0.1338 0.4073 1
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0776 0.235 0.3176
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Brugia malayi hypothetical protein 0.0127 0.0359 0.0485
Toxoplasma gondii exonuclease III APE 0.002 0.0033 0.0287
Entamoeba histolytica hypothetical protein 0.0024 0.0045 0.0364
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0017
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0012 0.0104
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0175 0.1513
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0018 0.0025 0.0027
Loa Loa (eye worm) 6-phosphofructokinase 0.0119 0.0336 0.0336
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.0113 0.0125
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0009
Echinococcus granulosus acetylcholinesterase 0.014 0.0399 0.0436
Mycobacterium ulcerans leucyl-tRNA synthetase 0.002 0.0033 0.0051
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0265 0.0289
Trichomonas vaginalis DNA-directed RNA polymerase III subunit, putative 0.0013 0.0012 0.0055
Chlamydia trachomatis DNA-directed RNA polymerase subunit beta 0.0259 0.0765 0.3668
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0042 0.0101
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0113 0.0123
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0222 0.065 0.1554
Brugia malayi RNA, U transporter 1 0.0084 0.0229 0.031
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1732 0.5282 0.5858
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0113 0.0269
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0013 0.0011 0.0012
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0409 0.1224 0.2925
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0175 0.0268
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.002 0.0031 0.0047
Brugia malayi Doublecortin family protein 0.0022 0.0037 0.005
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0175 0.0236
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.002 0.0031 0.0047
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0018 0.0025 0.0214
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0027 0.0037
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0113 0.0113
Schistosoma mansoni GMP synthetase 0.0037 0.0085 0.0203
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.005 0.0123 0.0123
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0024 0.0043 0.0048
Schistosoma mansoni vesicular amine transporter 0.0011 0.0005 0.0011
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.004 0.0093 0.0223
Treponema pallidum leucyl-tRNA synthetase 0.002 0.0033 0.0432
Schistosoma mansoni elf1 0.001 0.0001 0.0003
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.002 0.0031 0.0047
Echinococcus granulosus microtubule associated protein 2 0.1374 0.4185 0.457
Echinococcus granulosus protein C ets 2 0.001 0.0001 0.0001
Plasmodium vivax replication factor C subunit 1, putative 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0113 0.0123
Brugia malayi regulator of G-protein signaling egl-10 0.0038 0.0088 0.012
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Wolbachia endosymbiont of Brugia malayi DNA-directed RNA polymerase subunit beta/beta' 0.0259 0.0765 0.3668
Echinococcus multilocularis serotonin receptor 0.0046 0.0113 0.0125
Loa Loa (eye worm) dihydrofolate reductase 0.0285 0.0845 0.0845
Mycobacterium ulcerans 6-phosphofructokinase 0.0119 0.0336 0.0514
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0042 0.0042
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0037 0.0178
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0001 0.0001
Onchocerca volvulus 0.0018 0.0027 0.0067
Loa Loa (eye worm) hypothetical protein 0.005 0.0123 0.0123
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0037 0.0041
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0015 0.0017 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0098 0.027 0.0645
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0042 0.0101
Schistosoma mansoni ferritin light chain 0.0017 0.0023 0.0054
Onchocerca volvulus 0.0222 0.065 0.1596
Echinococcus multilocularis acetylcholinesterase 0.014 0.0399 0.0443
Brugia malayi steroid hormone receptor 0.0023 0.0042 0.0057
Onchocerca volvulus 0.0046 0.0113 0.0277
Trichomonas vaginalis conserved hypothetical protein 0.001 0 0.0001
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0077
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0116 0.0535
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi 6-phosphofructokinase 0.0119 0.0336 0.0454
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0042 0.0047
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.214 0.6531 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0011 0.0005 0.0011
Brugia malayi RE15519p 0.0046 0.0113 0.0152
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.025 0.0273
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0042 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0012 0.0055
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.002 0.0031 0.0047
Echinococcus multilocularis cpg binding protein 0.0033 0.0071 0.0079
Trypanosoma cruzi hypothetical protein 0.0013 0.0011 0.0097
Schistosoma mansoni voltage-gated potassium channel 0.0098 0.027 0.0645
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.0113 0.0269
Mycobacterium ulcerans NAD synthetase 0.0093 0.0256 0.0392
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0154 0.0236
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0113 0.0125
Toxoplasma gondii histone lysine methyltransferase SET1 0.007 0.0184 0.1596
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.0113 0.0125
Brugia malayi MH2 domain containing protein 0.0024 0.0044 0.006
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0776 0.235 0.3176
Toxoplasma gondii bifunctional GMP synthase/glutamine amidotransferase protein 0.0037 0.0085 0.0736
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0111 0.0121
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0011 0.0005 0.0006
Entamoeba histolytica acetyltransferase, GNAT family 0.0083 0.0227 0.1852
Brugia malayi nuclear hormone receptor family member odr-7 0.0011 0.0005 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Schistosoma mansoni neurotransmitter gated ion channel 0.0409 0.1224 0.2925
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0025 0.0214
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.0113 0.0123
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0367 0.1097 0.1483
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0025 0.0214
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0042 0.0042
Brugia malayi MH1 domain containing protein 0.0013 0.0012 0.0016
Plasmodium falciparum methionine--tRNA ligase 0.0053 0.0134 0.0643
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0027 0.003
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0083 0.0092
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0033 0.0153
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.006 0.0154 0.1331
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0027 0.0065
Echinococcus multilocularis tumor protein p63 0.0934 0.2834 0.3144
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0093 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0203
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Echinococcus granulosus glycine receptor subunit alpha 1 0.0776 0.235 0.2566
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.0113 0.0152
Brugia malayi phosphofructokinase 0.0119 0.0336 0.0454
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0053 0.0134 0.0642
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0031 0.0267
Echinococcus multilocularis DNA directed RNA polymerase III subunit RPC2 0.0013 0.0012 0.0013
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0036
Plasmodium falciparum GMP synthase [glutamine-hydrolyzing] 0.0037 0.0085 0.0408
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0409 0.1224 0.1654
Brugia malayi Carboxylesterase family protein 0.014 0.0399 0.054
Echinococcus multilocularis glycine receptor subunit beta 0.0776 0.235 0.2606
Brugia malayi DNA-directed RNA polymerase, beta subunit family protein 0.0013 0.0012 0.0016
Trypanosoma cruzi hypothetical protein 0.0013 0.0011 0.0097
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0113 0.0123
Schistosoma mansoni leucyl-tRNA synthetase 0.002 0.0033 0.008
Trypanosoma brucei calpain-like protein, putative 0.0239 0.0703 0.6087
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Echinococcus multilocularis snurportin 1 0.0316 0.094 0.1042
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0043 0.0104
Loa Loa (eye worm) hypothetical protein 0.0082 0.0221 0.0221
Toxoplasma gondii glutamine-dependent NAD(+) synthetase protein, putative 0.0093 0.0256 0.2217
Echinococcus granulosus histone acetyltransferase KAT2B 0.0091 0.025 0.0273
Echinococcus multilocularis smad 0.0024 0.0044 0.0049
Brugia malayi Smad1 0.0024 0.0044 0.006
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.007 0.0602
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0053 0.0134 0.0134
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.025 0.2168
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.0113 0.0269
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0119 0.0336 0.0514
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0017 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0199
Trypanosoma brucei hypothetical protein 0.0239 0.0703 0.6087
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0037 0.017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.002 0.0031 0.0267
Schistosoma mansoni microtubule-associated protein tau 0.1374 0.4185 1
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0043 0.0066
Schistosoma mansoni rab6-interacting 0.0022 0.0037 0.0089
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0017 0.0019
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0044 0.0048
Schistosoma mansoni ets-related 0.001 0.0001 0.0003
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0013 0.0011 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0013 0.0059
Schistosoma mansoni apoferritin-2 0.0017 0.0023 0.0054
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0033
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0044 0.0106
Echinococcus granulosus ETS transcription factor Elf 1 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Echinococcus multilocularis allatostatin A receptor 0.0046 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0066 0.0175 0.0268
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0187 0.0447
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Echinococcus granulosus GA binding protein alpha chain 0.0068 0.018 0.0197
Brugia malayi ecdysteroid receptor 0.0023 0.0042 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.001 0 0.0001
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0012 0.0009 0.0022
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0776 0.235 0.235
Mycobacterium leprae conserved hypothetical protein 0.007 0.0187 0.2214
Onchocerca volvulus 0.0409 0.1224 0.3005
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0013 0.0012 0.0104
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.0113 0.0123
Mycobacterium ulcerans carboxylesterase, LipT 0.0024 0.0043 0.0066
Schistosoma mansoni acetyl-CoA synthetase 0.002 0.0031 0.0074
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0776 0.235 0.2606
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0033 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0012 0.0055
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Plasmodium falciparum glutamine-dependent NAD(+) synthetase, putative 0.0093 0.0256 0.1228
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0154 0.0168
Loa Loa (eye worm) LGC-31 protein 0.0776 0.235 0.235
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0037 0.0041
Echinococcus multilocularis neuropeptide receptor A26 0.0948 0.2878 0.3192
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.1338 0.4073 0.4073
Brugia malayi hypothetical protein 0.054 0.1627 0.2199
Loa Loa (eye worm) hypothetical protein 0.0016 0.0021 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.025 0.0598
Onchocerca volvulus 0.0024 0.0043 0.0106
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0722
Trichomonas vaginalis set domain proteins, putative 0.0719 0.2174 1
Leishmania major DNA-directed RNA polymerase polypeptide, putative 0.0013 0.0012 0.0103
Plasmodium vivax DNA-directed RNA polymerase I subunit RPA2, putative 0.001 0 0.0001
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0477 0.0477
Brugia malayi Cytochrome P450 family protein 0.0018 0.0025 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0042 0.0057
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0113 0.0125
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0033 0.0101
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.002 0.0033 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0012 0.0055
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0044 0.0044
Brugia malayi hypothetical protein 0.0105 0.0294 0.0398
Echinococcus granulosus dihydrofolate reductase 0.0285 0.0845 0.0922
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.0113 0.0123
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0336 0.2744
Loa Loa (eye worm) nuclear factor I 0.0013 0.0012 0.0012
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0477 0.0529
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0386 0.1155 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0722
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.0113 0.0123
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.0113 0.0152
Echinococcus multilocularis methionine tRNA synthetase 0.0053 0.0134 0.0149
Loa Loa (eye worm) hypothetical protein 0.0022 0.0037 0.0037
Brugia malayi hypothetical protein 0.0367 0.1097 0.1483
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0159 0.038
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0042 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0005 0.0011
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0776 0.235 0.2606
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0239 0.0703 0.6087
Echinococcus multilocularis son of sevenless 1 0.0013 0.0011 0.0012
Brugia malayi hypothetical protein 0.0022 0.0037 0.005
Leishmania major phosphatidylinositol 3-kinase, putative 0.0013 0.0012 0.0104
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0013 0.0111
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0047
Echinococcus multilocularis protein C ets 2 0.001 0.0001 0.0001
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0285 0.0845 0.1293
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0017 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0113 0.0125
Schistosoma mansoni kinase 0.0049 0.012 0.0287
Plasmodium vivax acetyl-CoA synthetase, putative 0.002 0.0031 0.0094
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0776 0.235 0.2566
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0013 0.0011 0.0012
Schistosoma mansoni biogenic amine receptor 0.0046 0.0113 0.0269
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.001 0.0014
Echinococcus multilocularis neuroligin 0.0024 0.0043 0.0048
Echinococcus granulosus 6 phosphofructokinase 0.0119 0.0336 0.0367
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Brugia malayi MH2 domain containing protein 0.0351 0.1047 0.1415
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0111 0.0265
Trypanosoma brucei glucosidase, putative 0.0037 0.0083 0.0722
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0265 0.229
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.007 0.0334
Brugia malayi N-terminal motif family protein 0.0013 0.0011 0.0015
Onchocerca volvulus 0.0776 0.235 0.577
Echinococcus multilocularis thymidylate synthase 0.0222 0.065 0.0721
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0045 0.0205
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.0113 0.0123
Echinococcus multilocularis isocitrate dehydrogenase 0.0018 0.0025 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0082 0.0223 0.0244
Brugia malayi methionyl-tRNA synthetase 0.002 0.0033 0.0045
Trypanosoma cruzi hypothetical protein, conserved 0.001 0 0.0002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0265 0.229
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0383
Toxoplasma gondii methionyl-tRNA synthetase 0.0053 0.0134 0.1161
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0159 0.038
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0776 0.235 0.2566
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0 0.0001
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0031 0.0031
Schistosoma mansoni neuropeptide receptor 0.0046 0.0113 0.0269
Onchocerca volvulus 0.0046 0.0113 0.0277
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0383
Loa Loa (eye worm) hypothetical protein 0.005 0.0123 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0042 0.0057
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0042 0.0046
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.007 0.0333
Plasmodium falciparum importin beta, putative 0.003 0.0062 0.0296
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0013 0.0011 0.0012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0033 0.0033
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0149 0.0428 0.0428
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.004 0.0093 0.0807
Brugia malayi putative neuropeptide receptor 0.0046 0.0113 0.0152
Schistosoma mansoni coup transcription factor 0.0023 0.0042 0.0101
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0336 0.2744
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Brugia malayi larval opioid receptor 0.0046 0.0113 0.0152
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0013 0.0012 0.0029
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0367 0.1097 0.1097
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0042 0.0101
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0113 0.0113
Schistosoma mansoni apoferritin-2 0.0017 0.0023 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Echinococcus multilocularis serotonin receptor 0.0046 0.0113 0.0125
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0017 0.0018
Schistosoma mansoni ras GTP exchange factor 0.0013 0.0011 0.0027
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0115 0.0176
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0386 0.1155 1
Brugia malayi Dopamine receptor protein 1 0.0046 0.0113 0.0152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0043 0.0199
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0019 0.0029 0.0249
Echinococcus multilocularis lamin 0.0111 0.0312 0.0346
Schistosoma mansoni zinc finger protein 0.0011 0.0005 0.0011
Echinococcus granulosus g protein coupled receptor 0.0046 0.0113 0.0123
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.0023 0.0034
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0187 0.0207
Mycobacterium tuberculosis Hypothetical protein 0.0105 0.0294 0.045
Loa Loa (eye worm) transcription factor SMAD2 0.0351 0.1047 0.1047
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0005 0.0005
Echinococcus multilocularis carboxylesterase 5A 0.014 0.0399 0.0443
Mycobacterium ulcerans thymidylate synthase 0.0222 0.065 0.0996
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0015 0.0017 0.0023
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.025 0.0598
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0776 0.235 0.235
Brugia malayi neuropeptide F receptor 0.0046 0.0113 0.0152
Onchocerca volvulus 0.0066 0.0173 0.0425
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.005 0.0123 0.059
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0239 0.0703 0.6087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0113 0.0125
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0042 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.001 0 0.0002
Brugia malayi RasGEF domain containing protein 0.0013 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Entamoeba histolytica hypothetical protein 0.002 0.0032 0.0262
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0062 0.0534
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Schistosoma mansoni neuropeptide receptor 0.0046 0.0113 0.0269
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0025 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.0294 0.1353
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.007 0.0568
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0187 0.0286
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0042 0.0057
Echinococcus granulosus glycine receptor subunit alpha 1 0.0776 0.235 0.2566
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.006 0.0154 0.0236
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0032 0.0032
Brugia malayi Nuclear hormone receptor E75 0.0011 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Schistosoma mansoni neuroligin 3 (S09 family) 0.0024 0.0043 0.0104
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0011 0.0005 0.0005
Schistosoma mansoni z-protein (S1r protein) 0.0038 0.0088 0.0211
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0017 0.004
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.0113 0.0123
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0175 0.0268
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0013 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0116 0.0535
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Leishmania major importin beta-1 subunit, putative 0.0024 0.0045 0.0386
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0776 0.235 0.3176
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.004 0.0093 0.0762
Schistosoma mansoni polycystin 1-related 0.0022 0.0037 0.0089
Brugia malayi methionyl-tRNA synthetase 0.0053 0.0134 0.0181
Mycobacterium ulcerans acetyl-CoA synthetase 0.002 0.0031 0.0047
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0043
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0084 0.0228 0.0249
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0044 0.0049
Echinococcus multilocularis dnaJ subfamily B 0.0866 0.2627 0.2914
Onchocerca volvulus 0.0046 0.0113 0.0277
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0024 0.0043 0.02
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0042 0.0042
Onchocerca volvulus 0.0091 0.025 0.0615
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0011 0.0027
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0042 0.0057
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0187 0.0286
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.002 0.0031 0.0267
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0042 0.0047
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.0113 0.0269
Brugia malayi AMP-binding enzyme family protein 0.0066 0.0175 0.0236
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0011 0.0005 0.0005
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.002 0.0031 0.0267
Echinococcus multilocularis dihydrofolate reductase 0.0285 0.0845 0.0937
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Plasmodium vivax hypothetical protein, conserved 0.002 0.0033 0.0101
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0082 0.0223 0.0244
Plasmodium vivax SET domain protein, putative 0.0091 0.025 0.076
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.014 0.0399 0.0955
Onchocerca volvulus 0.0024 0.0043 0.0107
Schistosoma mansoni nAChR subunit 0.0367 0.1097 0.2621
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.0113 0.0125
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0115 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0037 0.017
Schistosoma mansoni dishevelled 0.0018 0.0027 0.0065
Toxoplasma gondii DNA-directed RNA polymerase I RPA2 0.001 0 0.0003
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0015 0.0017 0.004
Schistosoma mansoni lipoxygenase 0.006 0.0156 0.0374
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0776 0.235 0.2606
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.002 0.0031 0.0047
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.002 0.0033 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0037 0.017
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0285 0.0845 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0013 0.0105
Brugia malayi N-terminal motif family protein 0.0373 0.1116 0.1508
Brugia malayi cytoplasmic intermediate filament protein 0.006 0.0154 0.0208
Echinococcus granulosus g protein coupled receptor 0.0046 0.0113 0.0123
Schistosoma mansoni nuclear receptor 0.0011 0.0005 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0017 0.0018
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Brugia malayi hypothetical protein 0.0367 0.1097 0.1483
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0033 0.0431
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0033 0.0271
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0042 0.0101
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0033 0.0036
Onchocerca volvulus 0.0024 0.0043 0.0107
Loa Loa (eye worm) hypothetical protein 0.0066 0.0175 0.0175
Brugia malayi AKH receptor 0.0046 0.0113 0.0152
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0042 0.0047
Loa Loa (eye worm) hypothetical protein 0.0038 0.0088 0.0088
Loa Loa (eye worm) acetylcholinesterase 1 0.014 0.0399 0.0399
Trypanosoma cruzi target of rapamycin kinase 3 0.0032 0.0068 0.0591
Schistosoma mansoni intermediate filament proteins 0.0111 0.0312 0.0745
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0011 0.0027
Echinococcus multilocularis lamin dm0 0.0111 0.0312 0.0346
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0017 0.0019
Onchocerca volvulus 0.0046 0.0113 0.0277
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0013 0.0012 0.0104
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0265 0.0293
Echinococcus granulosus carboxylesterase 5A 0.014 0.0399 0.0436
Trichomonas vaginalis methionine-tRNA synthetase, putative 0.0053 0.0134 0.0617
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.004 0.0093 0.0807
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0036
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0159 0.0159
Brugia malayi AMP-binding enzyme family protein 0.002 0.0031 0.0042
Brugia malayi Cytochrome P450 family protein 0.0028 0.0058 0.0078
Brugia malayi MH1 domain containing protein 0.0024 0.0044 0.006
Plasmodium falciparum DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0012 0.0057
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.0113 0.0125
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0033 0.0037
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0265 0.229
Brugia malayi Carboxylesterase family protein 0.0024 0.0043 0.0059
Loa Loa (eye worm) D-ets-2 protein 0.001 0.0001 0.0001
Trichomonas vaginalis nh(3)-dependent NAD(+) synthetase, putative 0.0093 0.0256 0.1178
Loa Loa (eye worm) hypothetical protein 0.0137 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0082 0.0223 0.0223
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0024 0.0043 0.0047
Echinococcus multilocularis ewsr:fli fusion protein type 0.001 0.0001 0.0001
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0091 0.025 0.2163
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.0113 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.069 0.2085 0.3193
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0 0.0002
Echinococcus multilocularis GA binding protein alpha chain 0.0068 0.018 0.02
Loa Loa (eye worm) carboxylesterase 0.014 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.2423 0.7399 0.7399
Loa Loa (eye worm) hypothetical protein 0.0586 0.1766 0.1766
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0042 0.0057
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0013 0.0012 0.0104
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0012 0.0055
Brugia malayi Intermediate filament tail domain containing protein 0.0111 0.0312 0.0421
Schistosoma mansoni hypothetical protein 0.0082 0.0223 0.0533
Plasmodium falciparum methionine--tRNA ligase, putative 0.002 0.0033 0.016
Schistosoma mansoni acetylcholine receptor subunit beta 0.0367 0.1097 0.2621
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0001 0.0001
Brugia malayi Calcitonin receptor-like protein seb-1 0.0149 0.0428 0.0578
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Loa Loa (eye worm) RecQ helicase 0.0021 0.0034 0.0034
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0776 0.235 0.2606
Schistosoma mansoni adenoreceptor 0.0046 0.0113 0.0269
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Mycobacterium tuberculosis Conserved protein 0.007 0.0187 0.0286
Loa Loa (eye worm) hypothetical protein 0.0013 0.0011 0.0011
Entamoeba histolytica hypothetical protein 0.004 0.0093 0.0763
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Loa Loa (eye worm) Smad1 0.0024 0.0044 0.0044
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.002 0.0031 0.0365
Brugia malayi hypothetical protein 0.0035 0.008 0.0108
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0042 0.0046
Schistosoma mansoni dep domain containing protein 0.0018 0.0027 0.0065
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0013 0.0011 0.0012
Brugia malayi Ets-domain containing protein 0.001 0.0001 0.0002
Onchocerca volvulus 0.0046 0.0113 0.0277
Giardia lamblia Leucyl-tRNA synthetase 0.002 0.0033 0.1258
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0042 0.0047
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0013 0.0011 0.0027
Brugia malayi PXA domain containing protein 0.002 0.0032 0.0043
Brugia malayi Bloom's syndrome protein homolog 0.0021 0.0034 0.0046
Loa Loa (eye worm) hypothetical protein 0.014 0.0399 0.0399
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Loa Loa (eye worm) carboxylesterase 0.0024 0.0043 0.0043
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0113 0.0123
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0025 0.0214
Echinococcus multilocularis shaker cognate 0.0011 0.0005 0.0005
Brugia malayi nuclear receptor RXR 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Brugia malayi latrophilin 2 splice variant baaae 0.0102 0.0283 0.0383
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0015 0.0017 0.0018
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.002 0.0031 0.0365
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.0113 0.0123
Plasmodium vivax tryptophan-rich antigen (Pv-fam-a) 0.1085 0.3296 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0005 0.0005
Brugia malayi CXXC zinc finger family protein 0.0031 0.0066 0.0089
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0111 0.0121
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0011 0.0005 0.0011
Brugia malayi acetyltransferase, GNAT family protein 0.0309 0.0919 0.1243
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0042 0.0057
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0113 0.0125
Schistosoma mansoni hypothetical protein 0.004 0.0093 0.0223
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0012 0.0029
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0013 0.0111
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0027
Echinococcus granulosus fmrfamide receptor 0.0046 0.0113 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0009 0.0012
Toxoplasma gondii DNA-directed RNA polymerase II RPB2 0.0013 0.0012 0.0103
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.002 0.0031 0.0047
Schistosoma mansoni apoptosis regulator bax 0.0082 0.0223 0.0533
Echinococcus multilocularis ferritin 0.0017 0.0023 0.0025
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0004 0.0004
Schistosoma mansoni acetylcholine receptor-related 0.0367 0.1097 0.2621
Onchocerca volvulus 0.0719 0.2174 0.5338
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0056 0.0142 0.034
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0017 0.004
Mycobacterium ulcerans lipase LipD 0.007 0.0187 0.0286
Loa Loa (eye worm) hypothetical protein 0.0102 0.0283 0.0283
Plasmodium falciparum histone acetyltransferase GCN5 0.0083 0.0227 0.1087
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0027 0.0037
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.001 0 0.0001
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.069 0.2085 0.6326
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0004 0.0004
Trichomonas vaginalis DNA-directed RNA polymerase I subunit, putative 0.0013 0.0012 0.0055
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0033 0.0079
Trichomonas vaginalis esterase, putative 0.007 0.0187 0.086
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Plasmodium falciparum acetyl-CoA synthetase, putative 0.002 0.0031 0.0148
Echinococcus granulosus jun protein 0.0084 0.0228 0.0249
Treponema pallidum methionyl-tRNA synthetase 0.002 0.0033 0.0432
Schistosoma mansoni glutamine-dependent NAD(+) synthetase 0.0093 0.0256 0.0612
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0066 0.0175 0.0268
Loa Loa (eye worm) histone methyltransferase 0.0013 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) carboxylesterase 0.0024 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Leishmania major NAD synthase, putative 0.0093 0.0256 0.2217
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.0023 0.0034
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0367 0.1097 0.1198
Brugia malayi GMP synthase 0.0037 0.0085 0.0115
Schistosoma mansoni smad 0.0024 0.0044 0.0106
Echinococcus multilocularis musashi 0.0111 0.0312 0.0346
Brugia malayi hypothetical protein 0.002 0.0032 0.0043
Brugia malayi follicle stimulating hormone receptor 0.0533 0.1606 0.2171
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.0113 0.0269
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Loa Loa (eye worm) hypothetical protein 0.0098 0.027 0.027
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.005 0.0123 0.0123
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Echinococcus multilocularis DNA directed RNA polymerase I subunit RPA2 0.0013 0.0012 0.0013
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0032 0.0036
Plasmodium vivax acyl-CoA synthetase, putative 0.005 0.0123 0.0374
Echinococcus multilocularis nAChR subunit 0.0409 0.1224 0.1358
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0009 0.0009
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0776 0.235 0.2566
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0017 0.0078
Echinococcus granulosus tar DNA binding protein 0.0061 0.0159 0.0174
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Plasmodium vivax DNA-directed RNA polymerase II subunit RPB2, putative 0.0013 0.0012 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0042 0.0042
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0083 0.0383
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0681
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0082 0.0223 0.0302
Brugia malayi hypothetical protein 0.0018 0.0027 0.0037
Echinococcus granulosus acetylcholinesterase 0.014 0.0399 0.0436
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0011 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0031
Schistosoma mansoni ets 0.001 0.0001 0.0003
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0154 0.0208
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0042 0.0057
Brugia malayi nuclear receptor NHR-88 0.0023 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0004 0.0004
Schistosoma mansoni gliotactin 0.0024 0.0043 0.0104
Loa Loa (eye worm) hypothetical protein 0.0018 0.0027 0.0027
Schistosoma mansoni amine GPCR 0.0046 0.0113 0.0269
Brugia malayi PXA domain containing protein 0.002 0.0032 0.0043
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.0113 0.0125
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0032 0.0036
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0042 0.0047
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Onchocerca volvulus 0.007 0.0187 0.0459
Onchocerca volvulus 0.0096 0.0264 0.0648
Loa Loa (eye worm) phosphatidylinositol 3 0.0013 0.0012 0.0012
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0042 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0042 0.0057
Schistosoma mansoni hypothetical protein 0.051 0.1536 0.367
Giardia lamblia DNA-directed RNA polymerase subunit B 0.001 0 0.0015
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0015 0.0017 0.0017
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Loa Loa (eye worm) hypothetical protein 0.0014 0.0013 0.0013
Echinococcus multilocularis nAChR subunit 0.0776 0.235 0.2606
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0477 0.0521
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0238 0.026
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0009
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0042 0.0042
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0017 0.0017
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.0113 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.025 0.0598
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0776 0.235 0.5615
Entamoeba histolytica NAD synthetase, putative 0.0093 0.0256 0.2092
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0042 0.0057
Schistosoma mansoni cpg binding protein 0.0031 0.0066 0.0158
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0091 0.0123
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0037 0.0041
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0066 0.0175 0.0268
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.002 0.0031 0.0047
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0031
Echinococcus granulosus axis inhibition protein axin 0.002 0.0032 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0037 0.017
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0042 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Echinococcus multilocularis nuclear receptor nhr 48 0.0011 0.0005 0.0005
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.0113 0.0277
Echinococcus multilocularis GMP synthase (glutamine hydrolyzing) 0.0037 0.0085 0.0094
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0042 0.0101
Loa Loa (eye worm) RNA polymerase III 128kD subunit-PA 0.0013 0.0012 0.0012
Echinococcus multilocularis ETS transcription factor Elf 2 0.001 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0111 0.0312 0.034
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0113 0.0269
Echinococcus granulosus geminin 0.051 0.1536 0.1677
Brugia malayi dihydrofolate reductase family protein 0.0285 0.0845 0.1141
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0023 0.0042 0.0103
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.0113 0.0123
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.004 0.0093 0.0126
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0239 0.0703 0.6087
Brugia malayi Ets-domain containing protein 0.0068 0.018 0.0243
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0017 0.0023 0.0107
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0156 0.0173
Toxoplasma gondii propionate-CoA ligase 0.002 0.0031 0.0267
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0042 0.0047
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0013 0.0011 0.0012
Brugia malayi RasGEF domain containing protein 0.0013 0.0011 0.0015
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0336 0.2907
Echinococcus multilocularis BC026374 protein (S09 family) 0.0024 0.0043 0.0048
Echinococcus granulosus GPCR family 2 0.0047 0.0115 0.0126
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Entamoeba histolytica recQ family helicase, putative 0.0011 0.0005 0.0039
Echinococcus granulosus hyperpolarization activated cyclic 0.0015 0.0017 0.0018
Mycobacterium tuberculosis Conserved protein 0.007 0.0187 0.0286
Echinococcus granulosus glycine receptor subunit beta 0.0776 0.235 0.2566
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0098 0.027 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Schistosoma mansoni histamine h1 receptor 0.0046 0.0113 0.0269
Echinococcus multilocularis glycine receptor subunit beta 0.0776 0.235 0.2606
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.004 0.0093 0.0102
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.0113 0.0152
Echinococcus granulosus potassium voltage gated channel protein 0.0011 0.0005 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0042 0.0101
Schistosoma mansoni hypothetical protein 0.0039 0.0091 0.0218
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0367 0.1097 0.1217
Giardia lamblia Replication factor C, subunit 1 0.001 0 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0175 0.1513
Echinococcus granulosus ewsr:fli fusion protein type 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0012 0.0055
Echinococcus granulosus orexin receptor type 2 0.0046 0.0113 0.0123
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0042 0.0046
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0031 0.0142
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0025 0.0215
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0062 0.0534
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0032 0.0035
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Toxoplasma gondii hypothetical protein 0.0018 0.0027 0.0237
Brugia malayi hypothetical protein 0.0022 0.0037 0.005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0013 0.0011 0.0027
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0111 0.0312 0.0312
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0409 0.1224 0.1654
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0776 0.235 0.235
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Echinococcus granulosus para nitrobenzyl esterase 0.0024 0.0043 0.0047
Brugia malayi neuropeptide F receptor 0.0046 0.0113 0.0152
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0187 0.086
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0111 0.0111
Brugia malayi RNA binding protein 0.0061 0.0159 0.0215
Echinococcus multilocularis voltage gated potassium channel 0.0015 0.0017 0.0019
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.0123 0.0189
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0367 0.1097 0.1198
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0042 0.0042
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.007 0.0907
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0053 0.0134 0.0205
Brugia malayi sulfakinin receptor protein 0.0046 0.0113 0.0152
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0005
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0013 0.0111
Trichomonas vaginalis ferritin, putative 0.0017 0.0023 0.0104
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0113 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0077
Loa Loa (eye worm) GABA receptor subunit 0.0409 0.1224 0.1224
Plasmodium vivax SET domain containing protein 0.0012 0.0007 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.005 0.0232
Mycobacterium tuberculosis Possible penicillin-binding protein 0.045 0.1351 0.2068
Loa Loa (eye worm) hypothetical protein 0.0037 0.0085 0.0085
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0083 0.0383
Echinococcus granulosus histone acetyltransferase KAT2B 0.0301 0.0893 0.0975
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0533 0.1606 0.1606
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0336 0.1545
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Brugia malayi bZIP transcription factor family protein 0.0084 0.0228 0.0308
Giardia lamblia Histone acetyltransferase GCN5 0.0083 0.0227 0.8567
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0367 0.1097 0.1217
Schistosoma mansoni nuclear receptor nhr-48 0.0011 0.0005 0.0011
Onchocerca volvulus 0.0111 0.0312 0.0766
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.0113 0.0269
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0091 0.0123
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0027 0.003
Loa Loa (eye worm) DNA-directed RNA polymerase 0.0011 0.0005 0.0005
Plasmodium falciparum acyl-CoA synthetase 0.005 0.0123 0.0591
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0033 0.0045
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0265 0.065
Onchocerca volvulus Putative nachr subunit 0.0776 0.235 0.577
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0027 0.0067
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0013 0.0017
Brugia malayi Cation transporter family protein 0.0776 0.235 0.3176
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0045 0.0205
Loa Loa (eye worm) ACC-1 protein 0.0776 0.235 0.235
Echinococcus multilocularis potassium voltage gated channel protein 0.0011 0.0005 0.0005
Plasmodium vivax methionine--tRNA ligase, putative 0.0053 0.0134 0.0407
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.0113 0.0123
Onchocerca volvulus 0.0033 0.0072 0.0176
Entamoeba histolytica fatty acid elongase, putative 0.009 0.0246 0.2006
Schistosoma mansoni hypothetical protein 0.0047 0.0115 0.0276
Echinococcus granulosus neuropeptide receptor 0.0046 0.0113 0.0123
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0039 0.0091 0.079
Echinococcus multilocularis somatostatin receptor 0.0046 0.0113 0.0125
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.007 0.0211
Onchocerca volvulus 0.0046 0.0113 0.0277
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.0113 0.0123
Brugia malayi hypothetical protein 0.0367 0.1097 0.1483
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0031 0.0267
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0187 0.0286
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Schistosoma mansoni neuropeptide receptor 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis Smad4 0.0024 0.0044 0.0049
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0187 0.086
Brugia malayi transcription factor E74 isoform 0.001 0.0001 0.0002
Brugia malayi hypothetical protein 0.002 0.0032 0.0043
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0066 0.0175 0.0268
Schistosoma mansoni ets-related 0.0207 0.0606 0.1448
Schistosoma mansoni biogenic amine receptor 0.0046 0.0113 0.0269
Brugia malayi hypothetical protein 0.0011 0.0005 0.0006
Loa Loa (eye worm) CYP4Cod1 0.0018 0.0025 0.0025
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0776 0.235 0.5615
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0159 0.038
Echinococcus granulosus nAChR subunit 0.0776 0.235 0.2566
Brugia malayi hypothetical protein 0.0011 0.0005 0.0006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0024 0.0043 0.0104
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0113 0.0123
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0113 0.0269
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0027 0.003
Brugia malayi Dihydrofolate reductase 0.0285 0.0845 0.1141
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.0113 0.0113
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0042 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0336 0.1545
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0011 0.0005 0.0005
Mycobacterium leprae DNA-DIRECTED RNA POLYMERASE (BETA CHAIN) RPOB (TRANSCRIPTASE BETA CHAIN) (RNA POLYMERASE BETA SUBUNIT) 0.0259 0.0765 0.9058
Brugia malayi G-protein coupled receptor 0.0046 0.0113 0.0152
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0018 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0022 0.0037 0.0037
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0033 0.0079
Schistosoma mansoni hypothetical protein 0.0046 0.0113 0.0269
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0077
Schistosoma mansoni smad1 5 8 and 0.0024 0.0044 0.0106
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Giardia lamblia DNA-directed RNA polymerase subunit B 0.0013 0.0012 0.0451
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0013 0.0012 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0631 0.1907 0.1907
Schistosoma mansoni hypothetical protein 0.0046 0.0113 0.0269
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.0113 0.0125
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0088 0.0098
Trypanosoma cruzi DNA-directed RNA polymerase III, putative 0.0013 0.0012 0.0103
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0367 0.1097 0.1483
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0042 0.0101
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0776 0.235 0.5615
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0009 0.002
Schistosoma mansoni hypothetical protein 0.051 0.1536 0.367
Toxoplasma gondii ABC1 family protein 0.007 0.0187 0.1618
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0017 0.004
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0239 0.0703 0.6087
Mycobacterium ulcerans acyl-CoA synthetase 0.0066 0.0175 0.0268
Leishmania major leucyl-tRNA synthetase, putative 0.002 0.0033 0.0288
Loa Loa (eye worm) hypothetical protein 0.0054 0.0135 0.0135
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0033 0.0287
Treponema pallidum DNA-directed RNA polymerase subunit beta 0.0259 0.0765 1
Schistosoma mansoni topbp1 0.001 0 0.0001
Loa Loa (eye worm) beta-lactamase 0.007 0.0187 0.0187
Echinococcus granulosus ferritin 0.0017 0.0023 0.0025
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0367 0.1097 0.1217
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0187 0.086
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Onchocerca volvulus 0.0011 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0042 0.0101 0.0101
Echinococcus granulosus tumor protein p63 0.0934 0.2834 0.3095
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0047
Schistosoma mansoni ferritin light chain 0.0017 0.0023 0.0054
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Entamoeba histolytica DNA-directed RNA polymerase III subunit 127.6 kDa polypeptide, putative 0.0013 0.0012 0.0098
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0013 0.0059
Brugia malayi ORL1-like opioid receptor 0.0046 0.0113 0.0152
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Schistosoma mansoni regulator of G protein signaling 0.0038 0.0088 0.0211
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0058 0.0058
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Loa Loa (eye worm) hypothetical protein 0.0066 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0039 0.0091 0.0091
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0083 0.0113
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0011 0.0005 0.0005
Mycobacterium ulcerans hypothetical protein 0.0066 0.0175 0.0268
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0105 0.0294 0.2546
Onchocerca volvulus 0.0022 0.0037 0.0091
Onchocerca volvulus 0.0776 0.235 0.577
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0042 0.0057
Leishmania major ATP-dependent phosphofructokinase 0.0119 0.0336 0.2907
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0012 0.0098
Brugia malayi nuclear hormone receptor 0.0023 0.0042 0.0057
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0037 0.017
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0068 0.018 0.018
Schistosoma mansoni Smad4 0.0024 0.0044 0.0106
Loa Loa (eye worm) hypothetical protein 0.0024 0.0043 0.0043
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0367 0.1097 0.1483
Brugia malayi Dopamine receptor 0.0046 0.0113 0.0152
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0367 0.1097 0.1097
Echinococcus granulosus nAChR subunit 0.0409 0.1224 0.1337
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0033 0.0153
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.007 0.0333
Brugia malayi nuclear hormone receptor 0.0011 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0042 0.0046
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0047
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0142 0.0142
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.006 0.0154 0.0368
Loa Loa (eye worm) AMP-binding enzyme family protein 0.002 0.0031 0.0031
Giardia lamblia Methionyl-tRNA synthetase 0.0053 0.0134 0.507
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0037 0.017
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0011 0.0051
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0239 0.0703 0.6087
Schistosoma mansoni ferritin 0.0017 0.0023 0.0054
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0265 0.0265
Loa Loa (eye worm) hypothetical protein 0.1338 0.4073 0.4073
Giardia lamblia Kinase, PLK 0.0096 0.0265 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0042 0.0042
Schistosoma mansoni ferritin 0.0017 0.0023 0.0054
Toxoplasma gondii tRNA ligases class I (M) protein 0.002 0.0033 0.0288
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Brugia malayi Serotonin receptor 0.2013 0.6143 0.8302
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0032 0.0043
Schistosoma mansoni peripheral-type benzodiazepine receptor 0.1338 0.4073 0.9732
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0035
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.2423 0.7399 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0013 0.0059
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0017 0.0022 0.0188
Echinococcus granulosus lamin 0.0111 0.0312 0.034
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0 0.0001
Echinococcus granulosus son of sevenless 1 0.0013 0.0011 0.0012
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0175 0.1428
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0367 0.1097 0.1483
Chlamydia trachomatis methionine--tRNA ligase 0.002 0.0033 0.0159
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0187 0.1618
Trypanosoma brucei DNA-directed RNA polymerase III, putative 0.0013 0.0012 0.0103
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Loa Loa (eye worm) MH2 domain-containing protein 0.0351 0.1047 0.1047
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0013 0.0011 0.0012
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.004 0.0093 0.0807
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.0113 0.0125
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.0113 0.0152
Entamoeba histolytica fatty acid elongase, putative 0.009 0.0246 0.2006
Onchocerca volvulus 0.0023 0.0042 0.0103
Echinococcus multilocularis bloom syndrome protein 0.0021 0.0034 0.0038
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0032 0.0043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0054 0.0135 0.015
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0386 0.1155 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0025 0.0027
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.025 0.0278
Schistosoma mansoni DNA-directed RNA polymerase I subunit 0.001 0 0.0001
Chlamydia trachomatis dihydrofolate reductase 0.0285 0.0845 0.405
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0018 0.0025 0.0214
Schistosoma mansoni hypothetical protein 0.0082 0.0223 0.0533
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0156 0.0171
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.0113 0.0269
Mycobacterium tuberculosis Conserved protein 0.007 0.0187 0.0286
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0015 0.0017 0.004
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0187 0.1618
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Echinococcus granulosus importin subunit beta 1 0.003 0.0062 0.0067
Echinococcus granulosus voltage gated potassium channel 0.0015 0.0017 0.0018
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0776 0.235 0.3176
Echinococcus multilocularis geminin 0.051 0.1536 0.1704
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.006 0.0154 0.0236
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0113 0.0125
Mycobacterium leprae Probable methionyl-tRNA synthase MetS 0.0053 0.0134 0.1588
Echinococcus granulosus snurportin 1 0.0316 0.094 0.1026
Leishmania major hypothetical protein, conserved 0.007 0.0187 0.1618
Schistosoma mansoni ferritin 0.0017 0.0023 0.0054
Echinococcus multilocularis neuropeptide receptor 0.0046 0.0113 0.0125
Echinococcus granulosus RUN 0.0022 0.0037 0.0041
Trichomonas vaginalis ras GTP exchange factor, putative 0.0013 0.0011 0.0051
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0383
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.007 0.2629
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0 0.0001
Mycobacterium tuberculosis DNA-directed RNA polymerase (beta chain) RpoB (transcriptase beta chain) (RNA polymerase beta subunit) 0.0063 0.0165 0.0253
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0014 0.0014 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0012 0.0055
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.0113 0.0123
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0009 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.0075 0.0347
Echinococcus granulosus hypothetical protein 0.2997 0.9158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0265 0.0358
Echinococcus multilocularis Protein son of sevenless 0.0013 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0033
Brugia malayi hypothetical protein 0.0024 0.0043 0.0059
Brugia malayi TAR-binding protein 0.0061 0.0159 0.0215
Schistosoma mansoni topbp1 0.001 0 0.0001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0018 0.0025 0.0119
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.004 0.0093 0.0762
Schistosoma mansoni DNA-directed rna polymerase II subunit 0.0013 0.0012 0.0029
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0033 0.0033
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0159 0.0159
Trypanosoma cruzi NAD+ synthase, putative 0.0093 0.0256 0.2217
Schistosoma mansoni voltage-gated potassium channel 0.0015 0.0017 0.004
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0025 0.0215
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0068 0.0314
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0004 0.0005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0054 0.0135 0.0148
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0187 0.0286
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0 0.0002
Schistosoma mansoni acetylcholinesterase 0.0024 0.0043 0.0104
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.007 0.0211
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0776 0.235 0.2566
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0386 0.1155 1
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0015 0.0017 0.0017
Brugia malayi Dopamine receptor protein 2 0.0046 0.0113 0.0152
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Trypanosoma brucei calpain, putative 0.0239 0.0703 0.6087
Echinococcus granulosus shaker cognate 0.0011 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.002 0.0031 0.0042
Chlamydia trachomatis oxoacyl-ACP synthase III 0.069 0.2085 1
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0011 0.0005 0.0006
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.002 0.0031 0.0267
Echinococcus granulosus potassium voltage gated channel protein 0.0098 0.027 0.0295
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0032 0.0035
Schistosoma mansoni gabp alpha 0.0068 0.018 0.043
Brugia malayi MH2 domain containing protein 0.0011 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi 6-phosphofructokinase 0.0119 0.0336 0.0454
Mycobacterium ulcerans DNA-directed RNA polymerase subunit beta 0.0259 0.0765 0.1171
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0025 0.0025
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0011 0.0004 0.0009
Trypanosoma brucei cytochrome P450, putative 0.0018 0.0025 0.0215
Wolbachia endosymbiont of Brugia malayi leucyl-tRNA synthetase 0.002 0.0033 0.0159
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.0175 0.207
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0187 0.0286
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0115 0.0176
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.0113 0.0125
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0083 0.0681
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0187 0.0447
Plasmodium vivax glutamine-dependent NAD(+) synthetase, putative 0.0093 0.0256 0.0777
Loa Loa (eye worm) fli-1 protein 0.0207 0.0606 0.0606
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0015 0.0017 0.0019
Brugia malayi Importin beta-1 subunit 0.003 0.0062 0.0083
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0285 0.0845 0.1293
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.214 0.6531 1
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.001 0.0001 0.0003
Brugia malayi acetyl-Coenzyme A synthetase 2 0.002 0.0031 0.0042
Onchocerca volvulus 0.007 0.0187 0.0459
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Brugia malayi Cytochrome P450 family protein 0.0018 0.0025 0.0034
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0037 0.0041
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0111 0.0265
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0015 0.0017 0.0078
Onchocerca volvulus Bile acid receptor homolog 0.0023 0.0042 0.0103
Onchocerca volvulus 0.0776 0.235 0.577
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Schistosoma mansoni hypothetical protein 0.0068 0.018 0.043
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0093 0.0104
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0027 0.0027
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.069 0.2085 1
Trichomonas vaginalis phosphofructokinase, putative 0.0119 0.0336 0.1545
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Onchocerca volvulus 0.0046 0.0113 0.0277
Echinococcus granulosus neuropeptide receptor A26 0.0948 0.2878 0.3143
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0013 0.0059
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0115 0.0126
Schistosoma mansoni hypothetical protein 0.0102 0.0283 0.0676
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0776 0.235 0.2566
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0776 0.235 0.5615
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0009
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0018 0.0025 0.0038
Schistosoma mansoni myosin xvIII 0.0046 0.0113 0.0269
Trypanosoma brucei acetyl-CoA synthetase, putative 0.002 0.0031 0.0267
Echinococcus granulosus expressed protein 0.0017 0.0023 0.0025
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0013 0.0012 0.0013
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0187 0.0286
Schistosoma mansoni hypothetical protein 0.0046 0.0113 0.0269
Loa Loa (eye worm) acetyltransferase 0.0309 0.0919 0.0919
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.007 0.0334
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.007 0.0602
Schistosoma mansoni Smad4 0.0011 0.0004 0.0009
Entamoeba histolytica phosphofructokinase, putative 0.0119 0.0336 0.2744
Echinococcus multilocularis acetylcholinesterase 0.014 0.0399 0.0443
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.0023 0.0034
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0409 0.1224 0.1654
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0033 0.0045
Loa Loa (eye worm) intermediate filament protein 0.0111 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.0015 0.0017 0.0017
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0053 0.0134 0.1161
Echinococcus granulosus DNA directed RNA polymerase II subunit RPB2 0.0013 0.0012 0.0013
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0149 0.0428 0.0578
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0005 0.0005
Echinococcus granulosus sex peptide receptor 0.0046 0.0113 0.0123
Schistosoma mansoni hypothetical protein 0.0047 0.0115 0.0276
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.007 0.0602
Echinococcus granulosus translocator protein 0.1338 0.4073 0.4447
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0776 0.235 0.2606
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Brugia malayi G-protein coupled receptor 0.0046 0.0113 0.0152
Echinococcus granulosus Nuclear hormone receptor HR96 0.0011 0.0005 0.0005
Onchocerca volvulus 0.001 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Trypanosoma brucei polo-like protein kinase 0.0096 0.0265 0.229
Chlamydia trachomatis leucine--tRNA ligase 0.002 0.0033 0.0159
Loa Loa (eye worm) hypothetical protein 0.007 0.0187 0.0187
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0015 0.0017 0.0018
Loa Loa (eye worm) voltage-gated potassium channel 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0033 0.0159
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0409 0.1224 0.2925
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni smad1 5 8 and 0.0024 0.0044 0.0106
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.002 0.0031 0.0047
Echinococcus multilocularis translocator protein 0.1338 0.4073 0.4517
Brugia malayi conserved hypotetical protein 0.0011 0.0005 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Schistosoma mansoni hypothetical protein 0.0022 0.0037 0.0089
Onchocerca volvulus 0.0046 0.0113 0.0277
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0042 0.0101
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0776 0.235 0.2606
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.002 0.0031 0.0034
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0776 0.235 0.2566
Loa Loa (eye worm) acetylcholine receptor protein 0.0367 0.1097 0.1097
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0265 0.2162
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0159 0.038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0203
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0083 0.0383
Echinococcus granulosus ETS transcription factor Elf 2 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.002 0.0033 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0159 0.0215
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.004 0.0093 0.0807
Schistosoma mansoni methionine-tRNA synthetase 0.002 0.0033 0.008
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0038 0.0088 0.0088
Echinococcus granulosus ETS transcription factor Elf 5 0.001 0.0001 0.0001
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0011 0.0005 0.0005
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0115 0.0115
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0776 0.235 0.3176
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0042 0.0046
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0011 0.0011
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0776 0.235 0.2566
Trichomonas vaginalis DNA helicase recq, putative 0.0011 0.0005 0.0022
Plasmodium falciparum DNA-directed RNA polymerase I subunit RPA2, putative 0.001 0 0.0002
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.002 0.0033 0.0037
Echinococcus multilocularis microtubule associated protein 2 0.1374 0.4185 0.4642
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0309 0.0919 0.102
Loa Loa (eye worm) RasGEF domain-containing protein 0.0013 0.0011 0.0011
Schistosoma mansoni axis inhibition protein axin 0.002 0.0032 0.0077
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Brugia malayi Pre-SET motif family protein 0.0631 0.1907 0.2577
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0018 0.0025 0.0214
Entamoeba histolytica acyl-CoA synthetase, putative 0.0066 0.0175 0.1428
Loa Loa (eye worm) hypothetical protein 0.1338 0.4073 0.4073
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0042 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0083 0.0383
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0005 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0093 0.0429
Echinococcus granulosus neuropeptide receptor 0.0046 0.0113 0.0123
Loa Loa (eye worm) hypothetical protein 0.0058 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.004 0.0093 0.0763
Echinococcus granulosus potassium voltage gated channel protein 0.0011 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.014 0.0399 0.0399
Trichomonas vaginalis bromodomain-containing protein, putative 0.0091 0.025 0.115
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0776 0.235 0.235
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0187 0.0286
Onchocerca volvulus 0.007 0.0187 0.0459
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0044 0.0048
Brugia malayi MH2 domain containing protein 0.0024 0.0044 0.006
Echinococcus multilocularis hyperpolarization activated cyclic 0.0015 0.0017 0.0019
Onchocerca volvulus 0.0046 0.0113 0.0277
Echinococcus granulosus DNA directed RNA polymerase III subunit RPC2 0.0013 0.0012 0.0013
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.002 0.0031 0.0047
Schistosoma mansoni smad1 5 8 and 0.0024 0.0044 0.0106
Echinococcus granulosus glycine receptor subunit alpha 1 0.0776 0.235 0.2566
Onchocerca volvulus 0.0024 0.0043 0.0107
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.0113 0.0152
Schistosoma mansoni alpha-glucosidase 0.0142 0.0407 0.0972
Loa Loa (eye worm) thymidylate synthase 0.0222 0.065 0.065
Echinococcus granulosus g protein coupled receptor 0.0046 0.0113 0.0123
Brugia malayi small heat shock protein 0.0586 0.1766 0.2387
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.002 0.0031 0.0047
Echinococcus granulosus neuropeptide s receptor 0.0948 0.2878 0.3143
Loa Loa (eye worm) isocitrate dehydrogenase 0.0018 0.0025 0.0025
Loa Loa (eye worm) DR-78 0.0011 0.0005 0.0005
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.004 0.0093 0.0103
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0053 0.0134 0.1161
Echinococcus multilocularis ras GTP exchange factor 0.0013 0.0011 0.0012
Onchocerca volvulus 0.0011 0.0005 0.0011
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0 0.0003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0113 0.0269
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0083 0.0722
Loa Loa (eye worm) nuclear receptor NHR-67 0.0011 0.0005 0.0005
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Giardia lamblia GTOR 0.004 0.0093 0.3524
Schistosoma mansoni jun-related protein 0.0068 0.018 0.043
Onchocerca volvulus 0.0776 0.235 0.577
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0033 0.0051
Schistosoma mansoni DNA ligase IV 0.001 0 0.0001
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0032 0.0032
Mycobacterium tuberculosis Glutamine-dependent NAD(+) synthetase NadE (NAD(+) synthase [glutamine-hydrolysing]) 0.0093 0.0256 0.0392
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0091 0.025 0.2163
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.0113 0.0269
Brugia malayi Carboxylesterase family protein 0.014 0.0399 0.054
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0776 0.235 0.2606
Entamoeba histolytica hypothetical protein 0.001 0 0.0002
Schistosoma mansoni neurotransmitter gated ion channel 0.0367 0.1097 0.2621
Trypanosoma brucei DNA-directed RNA polymerase II subunit 2, putative 0.0013 0.0012 0.0103
Mycobacterium ulcerans GMP synthase 0.0037 0.0085 0.013
Schistosoma mansoni regulator of G protein signaling 0.002 0.0032 0.0077
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.069 0.2085 0.3193
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0032 0.0148
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.0113 0.0277
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.0113 0.0113
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.002 0.0031 0.0047
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0013 0.0059
Loa Loa (eye worm) tyrosyl-tRNA synthetase 0.0033 0.0072 0.0072
Trichomonas vaginalis antibiotic synthetase, putative 0.002 0.0031 0.0142
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0027 0.003
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.0113 0.0123
Schistosoma mansoni 6-phosphofructokinase 0.0119 0.0336 0.0803
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0309 0.0919 0.2197
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0013 0.0011 0.0097
Schistosoma mansoni methionine-tRNA synthetase 0.0053 0.0134 0.0321
Onchocerca volvulus 0.002 0.0031 0.0076
Echinococcus multilocularis conserved hypothetical protein 0.295 0.9016 1
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0031 0.0267
Schistosoma mansoni ap endonuclease 0.002 0.0033 0.0079
Entamoeba histolytica acyl-coA synthetase, putative 0.0066 0.0175 0.1428
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0031 0.0042
Echinococcus multilocularis importin subunit beta 1 0.003 0.0062 0.0068
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0187 0.0286
Schistosoma mansoni amine GPCR 0.0046 0.0113 0.0269
Schistosoma mansoni ferritin 0.0017 0.0023 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0053 0.0244
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.025 0.0598
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0018 0.0025 0.0075
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0013 0.0032
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.0025 0.0038
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Schistosoma mansoni alpha glucosidase 0.0037 0.0083 0.0199
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0011 0.0005 0.0005
Entamoeba histolytica hypothetical protein 0.0013 0.0011 0.0091
Brugia malayi hypothetical protein 0.0046 0.0113 0.0152
Schistosoma mansoni hypothetical protein 0.0047 0.0115 0.0276
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0365
Brugia malayi hypothetical protein 0.0367 0.1097 0.1483
Brugia malayi NC domain containing protein 0.0042 0.0101 0.0137
Schistosoma mansoni smad 0.0011 0.0004 0.0009
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.005 0.0123 0.0123
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0003
Echinococcus granulosus neuroligin 0.0024 0.0043 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0115 0.0176
Echinococcus multilocularis regulator of G protein signaling 7 0.0038 0.0088 0.0098
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0119 0.0336 0.2907
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0044 0.0203
Leishmania major 4-coumarate:coa ligase-like protein 0.0066 0.0175 0.1513
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0776 0.235 0.2606
Schistosoma mansoni hypothetical protein 0.0316 0.094 0.2246
Mycobacterium leprae Probable lipase LipE 0.007 0.0187 0.2214
Schistosoma mansoni nuclear receptor 0.0011 0.0005 0.0011
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0042 0.0057
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0119 0.0336 0.3977
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0115 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Loa Loa (eye worm) nuclear hormone receptor 0.0011 0.0005 0.0005
Echinococcus granulosus ras GTP exchange factor 0.0013 0.0011 0.0012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0042 0.0046
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Echinococcus granulosus cpg binding protein 0.0033 0.0071 0.0078
Treponema pallidum bacterioferrin (TpF1) 0.0017 0.0023 0.0291
Echinococcus granulosus nuclear receptor nhr 48 0.0011 0.0005 0.0005
Trichomonas vaginalis spcc417.12 protein, putative 0.0024 0.0043 0.02
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0111 0.0123
Schistosoma mansoni opsin-like receptor 0.0046 0.0113 0.0269
Brugia malayi Carboxylesterase family protein 0.0024 0.0043 0.0059
Brugia malayi isocitrate dehydrogenase 0.0018 0.0025 0.0033
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0042 0.0046
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0187 0.086
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0776 0.235 0.235
Schistosoma mansoni dihydrofolate reductase 0.0285 0.0845 0.2018
Onchocerca volvulus 0.0111 0.0312 0.0766
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0033 0.1255
Echinococcus granulosus GMP synthase glutamine hydrolyzing 0.0037 0.0085 0.0093
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0222 0.065 0.7699
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0239 0.0703 0.6087
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0023 0.0034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0776 0.235 0.5615
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0015 0.0017 0.0018
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0032 0.0036
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.002 0.0031 0.0034
Schistosoma mansoni ap endonuclease 0.002 0.0033 0.0079
Schistosoma mansoni cpg binding protein 0.0033 0.0071 0.0171
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0042 0.0101
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0068 0.0314
Echinococcus multilocularis DNA directed RNA polymerase II subunit RPB2 0.0013 0.0012 0.0013
Schistosoma mansoni nAChR subunit 0.0776 0.235 0.5615
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.007 0.032
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0113 0.0123
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0091 0.025 0.115
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0373 0.1116 0.2739
Echinococcus multilocularis fmrfamide receptor 0.0046 0.0113 0.0125
Echinococcus granulosus Protein son of sevenless 0.0013 0.0011 0.0012
Onchocerca volvulus 0.002 0.0031 0.0076
Schistosoma mansoni hypothetical protein 0.0866 0.2627 0.6278
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0024 0.0043 0.0066
Entamoeba histolytica DNA-directed RNA polymerase subunit, putative 0.0013 0.0012 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0111 0.0265
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0011 0.0005 0.0005
Schistosoma mansoni lipoxygenase 0.0022 0.0037 0.0089
Brugia malayi hypothetical protein 0.0018 0.0027 0.0037
Schistosoma mansoni dishevelled 0.0018 0.0027 0.0065
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0015 0.0017 0.0018
Onchocerca volvulus UPF0528 protein homolog 0.0042 0.0101 0.0248
Onchocerca volvulus 0.0409 0.1224 0.3005
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0015 0.0017 0.0019
Onchocerca volvulus 0.0046 0.0113 0.0277
Schistosoma mansoni amine GPCR 0.0046 0.0113 0.0269
Brugia malayi protein ZK524.3 0.002 0.0033 0.0045
Schistosoma mansoni hypothetical protein 0.0046 0.0113 0.0269
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0477 0.0529
Onchocerca volvulus 0.1338 0.4073 1
Mycobacterium ulcerans beta-lactamase 0.007 0.0187 0.0286
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0776 0.235 0.2566
Onchocerca volvulus 0.0367 0.1097 0.2693
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0009 0.0009
Onchocerca volvulus 0.0046 0.0113 0.0277
Brugia malayi ecdysone receptor 0.0011 0.0005 0.0006
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0091 0.025 0.0758
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0018 0.0025 0.0027
Schistosoma mansoni BC026374 protein (S09 family) 0.0024 0.0043 0.0104
Onchocerca volvulus 0.0367 0.1097 0.2693
Brugia malayi GnHR receptor homolog 0.0046 0.0113 0.0152
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0239 0.0703 0.6087
Plasmodium vivax DNA-directed RNA polymerase III subunit, putative 0.0013 0.0012 0.0036
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.0113 0.0113
Plasmodium falciparum DNA-directed RNA polymerase III subunit RPC2, putative 0.0013 0.0012 0.0057
Onchocerca volvulus 0.0022 0.0037 0.0091
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0033 0.0033
Schistosoma mansoni DNA-directed RNA polymerase III subunit 0.0013 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0187 0.0253
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0011 0.0005 0.0006
Echinococcus multilocularis leucyl tRNA synthetase 0.002 0.0033 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0021 0.0037 0.017
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0265 0.1217
Schistosoma mansoni amine GPCR 0.0046 0.0113 0.0269
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Brugia malayi G protein-coupled receptor 0.0046 0.0113 0.0152
Trichomonas vaginalis DNA helicase recq1, putative 0.0021 0.0034 0.0157
Brugia malayi intermediate filament protein 0.0111 0.0312 0.0421
Echinococcus multilocularis potassium voltage gated channel protein 0.0098 0.027 0.0299
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.0113 0.0152
Onchocerca volvulus 0.0013 0.0011 0.0027
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.0113 0.0269
Entamoeba histolytica fatty acid elongase, putative 0.009 0.0246 0.2006
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0066 0.0066
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0032 0.0077
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0093 0.0429
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.0113 0.0123
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0062 0.0534
Echinococcus granulosus regulator of G protein signaling 7 0.0038 0.0088 0.0097
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0187 0.0204
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0042 0.0057
Loa Loa (eye worm) ACC-1 protein 0.0776 0.235 0.235
Leishmania major methionyl-tRNA synthetase, putative 0.0053 0.0134 0.1161
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0316 0.094 0.094
Brugia malayi beta-lactamase family protein 0.007 0.0187 0.0253
Schistosoma mansoni alpha-glucosidase 0.0142 0.0407 0.0972
Echinococcus granulosus methionine tRNA synthetase 0.0053 0.0134 0.0146
Trypanosoma brucei NAD+ synthase, putative 0.0093 0.0256 0.2217
Trichomonas vaginalis conserved hypothetical protein 0.001 0 0.0001
Toxoplasma gondii isocitrate dehydrogenase 0.0018 0.0025 0.0214
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0013 0.0111
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0013 0.0012 0.0016
Echinococcus granulosus bloom syndrome protein 0.0021 0.0034 0.0037
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0032 0.0043
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.006 0.0154 0.0154
Toxoplasma gondii hypothetical protein 0.0042 0.0101 0.0875
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0115 0.0128
Echinococcus granulosus BC026374 protein S09 family 0.0024 0.0043 0.0047
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0068 0.0314
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0033 0.0051
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0032 0.0068 0.0591
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Brugia malayi thymidylate synthase 0.0222 0.065 0.0879
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0093 0.0257 0.0285
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0159 0.0176
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0045 0.0386
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0032 0.0036
Onchocerca volvulus 0.0137 0.039 0.0958
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.0113 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0011 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0187 0.1618
Loa Loa (eye worm) hypothetical protein 0.0149 0.0428 0.0428
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0111 0.0123
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0004 0.0004
Onchocerca volvulus 0.002 0.0031 0.0076
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0013 0.0012 0.0104
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0011 0.0005 0.0041
Echinococcus multilocularis transfer RNA-Gly 0.0011 0.0005 0.0005
Leishmania major GMP synthase, putative,glutamine amidotransferase, putative 0.0037 0.0085 0.0736
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0044 0.0044
Toxoplasma gondii ATPase, AAA family protein 0.001 0 0.0002
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0 0.0002
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.0113 0.0125
Onchocerca volvulus 0.0046 0.0113 0.0277
Mycobacterium ulcerans acyl-CoA synthetase 0.002 0.0031 0.0047
Entamoeba histolytica hypothetical protein 0.0409 0.1224 1
Loa Loa (eye worm) hypothetical protein 0.0367 0.1097 0.1097
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.0039 0.0091 0.0277
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0239 0.0703 0.6087
Brugia malayi Fli-1 protein 0.0207 0.0606 0.0819
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0082 0.0223 0.0533
Loa Loa (eye worm) hypothetical protein 0.0409 0.1224 0.1224
Brugia malayi Serotonin receptor 0.0046 0.0113 0.0152
Entamoeba histolytica fatty acid elongase, putative 0.009 0.0246 0.2006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.0113 0.0152
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0098 0.027 0.0295
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.0113 0.0123
Loa Loa (eye worm) hypothetical protein 0.0023 0.0042 0.0042
Echinococcus multilocularis 6 phosphofructokinase 0.0119 0.0336 0.0373
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0005 0.0005
Echinococcus multilocularis sex peptide receptor 0.0046 0.0113 0.0125
Mycobacterium tuberculosis Carboxylesterase LipT 0.0024 0.0043 0.0066
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.002 0.0031 0.0047
Brugia malayi nuclear receptor RXR 0.0011 0.0005 0.0006
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0222 0.065 0.0996
Echinococcus granulosus g-protein coupled receptor 0.0046 0.0113 0.0123
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0039 0.0091 0.0123
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Schistosoma mansoni amine GPCR 0.0046 0.0113 0.0269
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0037 0.0037
Brugia malayi Carboxylesterase family protein 0.0024 0.0043 0.0059
Schistosoma mansoni hypothetical protein 0.001 0.0001 0.0003
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.0113 0.0269
Schistosoma mansoni neurotransmitter gated ion channel 0.0367 0.1097 0.2621
Echinococcus granulosus DNA directed RNA polymerase I subunit RPA2 0.0013 0.0012 0.0013
Brugia malayi hypothetical protein 0.0066 0.0173 0.0234
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0066 0.0175 0.207
Leishmania major acetyl-CoA synthetase, putative 0.002 0.0031 0.0267
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.0113 0.0269
Loa Loa (eye worm) hypothetical protein 0.0109 0.0306 0.0306
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.0113 0.0125
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0083 0.0722
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0042 0.0057
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0084 0.0228 0.0253
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0033 0.0037
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0033 0.0287
Trichomonas vaginalis conserved hypothetical protein 0.001 0 0.0001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.002 0.0031 0.0267
Echinococcus multilocularis ets variant gene 4 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0062 0.0285
Brugia malayi TspO/MBR family protein 0.1338 0.4073 0.5505
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0115 0.0156
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0025 0.0025
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0776 0.235 0.3176
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Echinococcus multilocularis ETS domain containing protein Elk 1 0.001 0.0001 0.0001
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0093 0.0223
Leishmania major cytochrome p450-like protein 0.0018 0.0025 0.0215
Loa Loa (eye worm) hypothetical protein 0.0012 0.0009 0.0009
Echinococcus multilocularis expressed protein 0.0017 0.0023 0.0025
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.0023 0.0266
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.025 0.0278
Schistosoma mansoni hypothetical protein 0.0082 0.0223 0.0533
Echinococcus granulosus somatostatin receptor 0.0046 0.0113 0.0123
Brugia malayi nuclear receptor NHR-88 0.0011 0.0005 0.0006
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Echinococcus granulosus lamin dm0 0.0111 0.0312 0.034
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.0113 0.0123
Echinococcus granulosus serotonin receptor 0.0046 0.0113 0.0123
Onchocerca volvulus Protein ultraspiracle homolog 0.0023 0.0042 0.0103
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0367 0.1097 0.1483
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0037 0.0113
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0004 0.0017
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.069 0.2085 0.3193
Entamoeba histolytica fatty acid elongase, putative 0.009 0.0246 0.2006
Brugia malayi nuclear hormone receptor family member nhr-6 0.0011 0.0005 0.0006
Treponema pallidum NAD synthetase 0.0093 0.0256 0.3345
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Loa Loa (eye worm) hypothetical protein 0.0091 0.025 0.025
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0776 0.235 0.2606
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.069 0.2085 0.3193
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0013 0.0059
Brugia malayi hypothetical protein 0.0012 0.0009 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.0113 0.0269
Toxoplasma gondii target of rapamycin (TOR), putative 0.003 0.0062 0.0536
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0183 0.0437
Brugia malayi MH1 domain containing protein 0.0024 0.0044 0.006
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0776 0.235 0.3176
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0011 0.0005 0.0011
Schistosoma mansoni nAChR subunit 0.0367 0.1097 0.2621
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.0113 0.0123
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0776 0.235 0.3176
Loa Loa (eye worm) oxidoreductase 0.002 0.0031 0.0031
Schistosoma mansoni cellular tumor antigen P53 0.0137 0.039 0.0932
Schistosoma mansoni rab6-interacting 0.0022 0.0037 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0013 0.0059
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0 0.0001
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.0113 0.0269
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.002 0.0031 0.0047
Loa Loa (eye worm) hypothetical protein 0.0052 0.0129 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.0113 0.0125
Brugia malayi Carboxylesterase family protein 0.0024 0.0043 0.0059
Loa Loa (eye worm) RGS-3 protein 0.002 0.0032 0.0032
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0046 0.0113 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.007 0.032
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.002 0.0031 0.0042
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.0113 0.0113
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.0113 0.0125
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0033 0.0287
Echinococcus multilocularis jun protein 0.0084 0.0228 0.0253
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0 0.0001
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.006 0.0154 0.0171
Echinococcus granulosus thymidylate synthase 0.0222 0.065 0.071
Onchocerca volvulus 0.1338 0.4073 1
Echinococcus granulosus dnaJ subfamily B 0.0866 0.2627 0.2869
Giardia lamblia NH3-dependent NAD+ synthetase 0.0093 0.0256 0.9678
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0115 0.0156
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0005 0.0005
Echinococcus multilocularis g protein coupled receptor 0.0046 0.0113 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.0113 0.0269
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0045 0.0205
Entamoeba histolytica hypothetical protein 0.004 0.0093 0.0763
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0386 0.1155 0.5541
Loa Loa (eye worm) hypothetical protein 0.1338 0.4073 0.4073
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0093 0.0429
Schistosoma mansoni opsin-like receptor 0.0046 0.0113 0.0269
Brugia malayi RasGEF domain containing protein 0.0013 0.0011 0.0015
Brugia malayi DNA-directed RNA polymerase II second largest subunit, putative 0.0013 0.0012 0.0016
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.069 0.2085 1
Onchocerca volvulus 0.0367 0.1097 0.2693
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0013 0.0011 0.0091
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0042 0.0047
Echinococcus multilocularis GPCR, family 2 0.0047 0.0115 0.0128
Loa Loa (eye worm) hypothetical protein 0.0047 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0776 0.235 0.235
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0477 0.0645
Echinococcus multilocularis orexin receptor type 2 0.0046 0.0113 0.0125
Trichomonas vaginalis DNA helicase recq, putative 0.0021 0.0034 0.0157
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0018 0.0025 0.0027
Echinococcus granulosus smad 0.0024 0.0044 0.0048
Brugia malayi Pre-SET motif family protein 0.0091 0.025 0.0338
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0409 0.1224 0.1654
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0032 0.0077
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0386 0.1155 0.3505
Schistosoma mansoni opsin-like receptor 0.0046 0.0113 0.0269
Onchocerca volvulus 0.0031 0.0066 0.0162
Plasmodium vivax hypothetical protein, conserved 0.007 0.0187 0.0567
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.033 0.0982 0.0982
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0037 0.0041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0068 0.0314
Onchocerca volvulus 0.0024 0.0043 0.0107
Plasmodium vivax methionine--tRNA ligase, putative 0.002 0.0033 0.0101
Echinococcus granulosus mixed lineage leukemia protein mll 0.0011 0.0005 0.0005
Brugia malayi AMP-binding enzyme family protein 0.002 0.0031 0.0042

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 20 mM In vitro inhibitory activity against sialyl Lewisx expressing HL60 cell binding Selectin P ChEMBL. 8544173
IC50 (binding) = 20 mM In vitro inhibition of HL60 (human leukaemia) cell binding to human recombinant e-selectin. ChEMBL. 8544173
Inhibition (binding) = 0 % In vitro inhibitory activity against sialyl Lewisx expressing HL60 cell binding to recombinant human E-selectin at 40 mM concentration ChEMBL. 8544173
Inhibition (binding) = 0 % In vitro inhibitory activity against sialyl Lewisx expressing HL60 cell binding to Selectin L at 6 mM concentration ChEMBL. 8544173
Inhibition (binding) = 30 % In vitro inhibitory activity against sialyl Lewisx expressing HL60 cell binding Selectin P at 10 mM concentration ChEMBL. 8544173
Inhibition (binding) = 40 % In vitro inhibitory activity against sialyl Lewisx expressing HL60 cell binding to Selectin L at 6 mM concentration ChEMBL. 8544173

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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